Leonardo Scarpellino

Publications | Mémoires et thèses

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37 publications

2023 | 2022 | 2020 | 2019 | 2018 | 2017 | 2016 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2005 | 2004 | 2003 | 2000 | 1999 | 1997 | 1996 | 1993 | 1992 | 1991 | 1990 |
2023
Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination.
Juilland M., Alouche N., Ubezzi I., Gonzalez M., Rashid H.O., Scarpellino L., Erdmann T., Grau M., Lenz G., Luther S.A. et al., 2023/12/26. Proceedings of the National Academy of Sciences of the United States of America, 120 (52) pp. e2301155120. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_9C724DAA6D7C]
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Corria-Osorio J., Carmona S.J., Stefanidis E., Andreatta M., Ortiz-Miranda Y., Muller T., Rota I.A., Crespo I., Seijo B., Castro W. et al., 2023/05. Nature immunology, 24 (5) pp. 869-883. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B6529135A8DD]
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx A.F., Kallert S.M., Brunner T.M., Villegas J.A., Geier F., Fixemer J., Abreu-Mota T., Reuther P., Bonilla W.V., Fadejeva J. et al., 2023/04/11. Immunity, 56 (4) pp. 813-828.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_796365D38E1A]
2022
In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B., Reverte M., Ronet C., Prevel F., Morgenthaler F.D., Desponds C., Lye L.F., Owens K.L., Scarpellino L., Dubey L.K. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941860. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2B104E1E8C7E]
2020
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.
Pais Ferreira D., Silva J.G., Wyss T., Fuertes Marraco S.A., Scarpellino L., Charmoy M., Maas R., Siddiqui I., Tang L., Joyce J.A. et al., 2020/11/17. Immunity, 53 (5) pp. 985-1000.e11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A0FD9237651F]
2019
 
TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.
Ronet C., Passelli K., Charmoy M., Scarpellino L., Myburgh E., Hauyon La Torre Y., Turco S., Mottram J.C., Fasel N., Luther S.A. et al., 2019/06. The Journal of investigative dermatology, 139 (6) pp. 1318-1328. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8AC775CA2A74]
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I., Schaeuble K., Chennupati V., Fuertes Marraco S.A., Calderon-Copete S., Pais Ferreira D., Carmona S.J., Scarpellino L., Gfeller D., Pradervand S. et al., 2019/01/15. Immunity, 50 (1) pp. 195-211.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8DBCBF3E53B5]
2018
 
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.
Huang H.Y., Rivas-Caicedo A., Renevey F., Cannelle H., Peranzoni E., Scarpellino L., Hardie D.L., Pommier A., Schaeuble K., Favre S. et al., 2018. Proceedings of the National Academy of Sciences of the United States of America, 115 (29) pp. E6826-E6835. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_32DF0F646EFA]
2017
Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.
Schaeuble K., Britschgi M.R., Scarpellino L., Favre S., Xu Y., Koroleva E., Lissandrin TKA, Link A., Matloubian M., Ware C.F. et al., 2017/11/28. Cell reports, 21 (9) pp. 2500-2514. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BD5BF80996B]
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J., Ebens C.L., Perkey E., Radojcic V., Koch U., Scarpellino L., Tong A., Allen F., Wood S., Feng J. et al., 2017. Journal of Clinical Investigation, 127 (4) pp. 1574-1588. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7C9AA9DC3589]
2016
 
Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.
Chennupati V., Koch U., Coutaz M., Scarpellino L., Tacchini-Cottier F., Luther S.A., Radtke F., Zehn D., MacDonald H.R., 2016/08/01. Journal of immunology, 197 (3) pp. 771-782. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D6B2134FFAED]
2014
 
Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes.
Yang C.Y., Vogt T.K., Favre S., Scarpellino L., Huang H.Y., Tacchini-Cottier F., Luther S.A., 2014. Proceedings of the National Academy of Sciences of the United States of America, 111 (1) pp. E109-E118.
[DOI][WoS][Pmid][serval:BIB_02A4AEE7F513]
2013
 
Inducible gene expression in fetal thymic epithelium: A new BAC transgenic model.
Fiorini E., Ferrero I., Poisson C., Scarpellino L., Luther S.A., Macdonald H.R., 2013. Genesis, 51 (10) pp. 717-724.
[DOI][WoS][Pmid][serval:BIB_3195E93EBE2A]
2011
Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.
Siegert S., Huang H.Y., Yang C.Y., Scarpellino L., Carrie L., Essex S., Nelson P.J., Heikenwalder M., Acha-Orbea H., Buckley C.D. et al., 2011. PLoS One, 6 (11) pp. e27618.
[URN][DOI][WoS][Pmid][serval:BIB_E37A5F5E8F2F]
2010
 
Probing the interactions of NK cell receptors with ligand expressed in trans and cis.
Back J., Scarpellino L., Held W., 2010. Methods in Molecular Biology, 612 pp. 313-323.
[DOI][WoS][Pmid][serval:BIB_4031ECF390EE]
2009
 
A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education.
Chalifour A., Scarpellino L., Back J., Brodin P., Devèvre E., Gros F., Lévy F., Leclercq G., Höglund P., Beermann F. et al., 2009. Immunity, 30 (3) pp. 337-347. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_891F521C981B]
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
Back J., Malchiodi E.L., Cho S., Scarpellino L., Schneider P., Kerzic M.C., Mariuzza R.A., Held W., 2009. Immunity, 31 (4) pp. 598-608. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B901DC34A80]
2008
 
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin
Jeannet G., Scheller M., Scarpellino L., Duboux S., Gardiol N., Back J., Kuttler F., Malanchi I., Birchmeier W., Leutz A. et al., 2008. Blood, 111 (1) pp. 142-149. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6996BFD53E08]
 
Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways
Coudert J. D., Scarpellino L., Gros F., Vivier E., Held W., 2008. Blood, 111 (7) pp. 3571-3578. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E3AF42B65712]
2007
 
Interactions of Ly49 family receptors with MHC class I ligands in trans and cis.
Scarpellino L., Oeschger F., Guillaume P., Coudert J.D., Lévy F., Leclercq G., Held W., 2007. Journal of immunology, 178 (3) pp. 1277-1284. Peer-reviewed.
[WoS][Pmid][serval:BIB_B4CA2A35F031]
 
Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact.
Back J., Chalifour A., Scarpellino L., Held W., 2007. Proceedings of the National Academy of Sciences of the United States of America, 104 (10) pp. 3978-3983. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E7C8E1827B15]
2005
 
Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.
Goux D., Coudert J.D., Maurice D., Scarpellino L., Jeannet G., Piccolo S., Weston K., Huelsken J., Held W., 2005. Blood, 106 (5) pp. 1726-1733. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D7D4A7A31084]
2004
 
Cis association of Ly49A with MHC class I restricts natural killer cell inhibition.
Doucey M.A., Scarpellino L., Zimmer J., Guillaume P., Luescher I.F., Bron C., Held W., 2004. Nature Immunology, 5 (3) pp. 328-336. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_84274940A2AD]
2003
 
Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1.
Ioannidis V., Kunz B., Tanamachi D.M., Scarpellino L., Held W., 2003. Journal of immunology, 171 (2) pp. 769-775. Peer-reviewed.
[WoS][Pmid][serval:BIB_DF924B269DD1]
2000
 
Pseudoprolines: Targeting a cis Conformation in a Mimetic of the gp120 V3 Loop of HIV-1 We are grateful to Dipl.-Biol. Raymond Jacquet for helpful advice. This work was supported by the Swiss National Science Foundation.
Wittelsberger A., Keller M., Scarpellino L., Patiny L., Acha-Orbea H., Mutter M., 2000. Angewandte Chemie, 39 (6) pp. 1111-1115.
[DOI][WoS][Pmid][serval:BIB_395B402DAEA5]
1999
 
Interplays between mouse mammary tumor virus and the cellular and humoral immune response.
Acha-Orbea H., Finke D., Attinger A., Schmid S., Wehrli N., Vacheron S., Xenarios I., Scarpellino L., Toellner K.M., MacLennan I.C. et al., 1999. Immunological Reviews, 168 pp. 287-303.
[DOI][WoS][Pmid][serval:BIB_FD0A307D70FA]
1997
 
Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells.
Luther S.A., Maillard I., Luthi F., Scarpellino L., Diggelmann H., Acha-Orbea H., 1997. Journal of Immunology, 159 (6) pp. 2807-2814.
[WoS][Pmid][serval:BIB_661]
1996
 
CD28/CTLA4-B7 interaction is dispensable for T cell stimulation by mouse mammary tumor virus superantigen but not for B cell differentiation and virus dissemination.
Champagne E., Scarpellino L., Lane P., Acha-Orbea H., 1996. European Journal of Immunology, 26 (7) pp. 1595-1602.
[DOI][WoS][Pmid][serval:BIB_0BA06B1850C3]
1993
 
Exogenous and endogenous mouse mammary tumor virus superantigens.
Acha-Orbea H., Held W., Waanders G.A., Shakhov A.N., Scarpellino L., Lees R.K., MacDonald H.R., 1993. Immunological Reviews, 131 (1) pp. 5-25.
[DOI][WoS][Pmid][serval:BIB_8C4921C5AC29]
 
Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission.
Held W., Waanders G.A., Shakhov A.N., Scarpellino L., Acha-Orbea H., MacDonald H.R., 1993. Cell, 74 (3) pp. 529-540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_958C4C50E223]
Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus.
Held W., Shakhov A.N., Izui S., Waanders G.A., Scarpellino L., MacDonald H.R., Acha-Orbea H., 1993. Journal of Experimental Medicine, 177 (2) pp. 359-366. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_80C31902CC51]
1992
An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv-7).
Held W., Shakhov A.N., Waanders G., Scarpellino L., Luethy R., Kraehenbuhl J.P., MacDonald H.R., Acha-Orbea H., 1992. Journal of Experimental Medicine, 175 (6) pp. 1623-1633.
[URN][DOI][WoS][Pmid][serval:BIB_34B1C10DA8A9]
Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein.
Acha-Orbea H., Scarpellino L., Shakhov A.N., Held W., MacDonald H.R., 1992. Journal of Experimental Medicine, 176 (6) pp. 1769-1772.
[URN][DOI][WoS][Pmid][serval:BIB_35F3DCDA65DB]
 
Mls: a link between immunology and retrovirology.
Acha-Orbea H., Held W., Scarpellino L., Shakhov A.N., 1992. International Reviews of Immunology, 8 (4) pp. 327-336.
[Pmid][serval:BIB_52CCC12C0007]
1991
 
Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus.
Acha-Orbea H., Shakhov A.N., Scarpellino L., Kolb E., Müller V., Vessaz-Shaw A., Fuchs R., Blöchlinger K., Rollini P., Billotte J. et al., 1991. Nature, 350 (6315) pp. 207-211.
[DOI][WoS][Pmid][serval:BIB_8A25A981E53A]
 
Nonobese diabetic and nonobese nondiabetic mice have unique MHC class II haplotypes.
Acha-Orbea H., Scarpellino L., 1991. Immunogenetics, 34 (1) pp. 57-59.
[DOI][WoS][Pmid][serval:BIB_5CB06B871A71]
1990
 
Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides.
Acha-Orbea H., Scarpellino L., Hertig S., Dupuis M., Tschopp J., 1990. EMBO Journal, 9 (12) pp. 3815-3819.
[WoS][Pmid][serval:BIB_80CCB8A48F89]
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