Haithem Chtioui

Publications | Mémoires et thèses

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56 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2007 | 2006 | 2005 |
2024
Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use.
Dao K., Buettcher M., Golhen K., Kost J., Schittny A., Duthaler U., Atkinson A., Haefliger D., Guidi M., Bardinet C. et al., 2024/10. Journal of clinical pharmacology, 64 (10) pp. 1295-1303. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6FBF4894C204]
 
Population Pharmacokinetics of Trametinib and Impact of Nonadherence on Drug Exposure in Oncology Patients as Part of the Optimizing Oral Targeted Anticancer Therapies Study.
Ravix A., Bandiera C., Cardoso E., Lata-Pedreira A., Chtioui H., Decosterd L.A., Wagner A.D., Schneider M.P., Csajka C., Guidi M., 2024/06/11. Cancers, 16 (12). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3DC9393D4173]
 
Immunomodulation profile of the biosimilar trastuzumab MYL-1401O in a bioequivalence phase I study.
Audran R., Chtioui H., Thierry A.C., Mayor C.E., Vallotton L., Dao K., Rothuizen L.E., Maghraoui A., Pennella E.J., Brunner-Ferber F. et al., 2024/06/04. Scientific reports, 14 (1) p. 12872. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_728141A25F81]
 
Pharmacovigilance. Sevrage et effet rebond: pas seulement avec les psychotropes [Pharmacovigilance. Withdrawal and rebound effects: not just with psychotropic drugs]
Marouf R., Chtioui H., Girardin F.R., Buclin T., Diezi L., 2024/01/17. Revue medicale suisse, 20 (856-7) pp. 96-101. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_22BF36045EE8]
2023
5-Fluorouracil-associated severe hypertriglyceridaemia with positive rechallenge.
Giacomuzzi Moore B., Durigova A., Lamine F., Chtioui H., Salati E., 2023/12/19. BMJ case reports, 16 (12). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_E970BBCD043C]
Elevated liver function tests in a patient with breast cancer.
Neftel C., Zaman K., Chtioui H., Moradpour D., Sempoux C., Fraga M., 2023/09. Journal of hepatology, 79 (3) pp. e109-e111. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E70D878557D9]
An innovative ethosuximide granule formulation designed for pediatric use: Comparative pharmacokinetics, safety, tolerability, and palatability profile versus reference syrup.
Diezi L., Dao K., Jullien V., Roussel-Maupetit C., Burton I., André P., Bardinet C., Rothuizen L.E., Chtioui H., Manso-Silvan M.A. et al., 2023/02. Pharmacology research & perspectives, 11 (1) pp. e01032. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8A3E445B0338]
Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V., Guinchard S., Marques S., Vocat A., Moulfi F., Versace F., Huser-Pitteloud J., Ivanyuk A., Bardinet C., Makarov V. et al., 2023/01/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1215 p. 123555. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_405A2D6AF487]
Estimating glomerular filtration rate from serum creatinine concentration in children with augmented renal clearance: all formulas are equivocal, but some are more equivocal than others.
André P., Chtioui H., Dao K., Rothuizen L.E., Di Paolo E.R., Diezi M., Crisinel P.A., Cachat F., Chehade H., Buclin T., 2023/01. Kidney international, 103 (1) pp. 225-226. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E06602D511F4]
2022
Systematic comparison with autoimmune liver disease identifies specific histological features of immune checkpoint inhibitor-related adverse events.
Coukos A., Vionnet J., Obeid M., Bouchaab H., Peters S., Latifyan S., Wicky A., Michielin O., Chtioui H., Moradpour D. et al., 2022/10. Journal for immunotherapy of cancer, 10 (10) pp. e005635. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F836C2B098EA]
 
Hepatitis B reactivation during ruxolitinib treatment.
Sjoblom M., Chtioui H., Fraga M., Stalder G., Grandoni F., Blum S., 2022/09. Annals of hematology, 101 (9) pp. 2081-2086. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_97208521780E]
Métabolisme et suivi thérapeutique de l’azathioprine en gastroentérologie et hépatologie [Metabolism and therapeutic monitoring of azathioprine in gastroenterology and hepatology]
Bianchetti D., Salvador Nunes L., André P., Schoepfer A., Moradpour D., Chtioui H., 2022/08/31. Revue medicale suisse, 18 (793) pp. 1588-1593. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8BF7916B0E8B]
Quantification of serotonin and eight of its metabolites in plasma of healthy volunteers by mass spectrometry.
Eugster P.J., Dunand M., Grund B., Ivanyuk A., Fogarasi Szabo N., Bardinet C., Abid K., Buclin T., Grouzmann E., Chtioui H., 2022/08/10. Clinica chimica acta; international journal of clinical chemistry, 535 pp. 19-26. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7C0E1266F726]
Population Pharmacokinetics of Palbociclib and Its Correlation with Clinical Efficacy and Safety in Patients with Advanced Breast Cancer.
Courlet P., Cardoso E., Bandiera C., Stravodimou A., Zurcher J.P., Chtioui H., Locatelli I., Decosterd L.A., Darnaud L., Blanchet B. et al., 2022/06/21. Pharmaceutics, 14 (7) p. 1317. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E7FBC59504B2]
Development of an assay by liquid chromatography coupled to tandem mass spectrometry for thiopurines drugs in whole blood and application for their Therapeutic Drug Monitoring
Nguyen N., Da Silva Pereira Clara J. A., Mercier T., Desfontaines V., Ceppi F., Moradpour D., Chtioui H., André P., Buclin T., Decosterd L. A. et al., 2022/06/01. dans 6ème Congrès de printemps de la Société Suisse de Médecine Interne Générale du 1er juin 2022.
[URN][serval:BIB_144D7BE019DE]
Pharmacovigilance - Vaccins à ARNm contre le Covid-19 : le point sur les effets indésirables [Pharmacovigilance - mRNA COVID-19 vaccines : current state of knowledge on their adverse effects]
Favre V., Ekobena P., Chtioui H., Rothuizen L.E., Livio F., Genton B., Buclin T., 2022/02/02. Revue medicale suisse, 18 (767) pp. 190-197. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C87F5371DEBD]
 
Ensuring Sufficient Trough Plasma Concentrations for Broad-Spectrum Beta-Lactam Antibiotics in Children With Malignancies: Beware of Augmented Renal Clearance!
André P., Diezi L., Dao K., Crisinel P.A., Rothuizen L.E., Chtioui H., Decosterd L.A., Diezi M., Asner S., Buclin T., 2022. Frontiers in pediatrics, 9 p. 768438. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B465A6064AF2]
Iberogast®-Induced Acute Liver Injury-A Case Report.
Leroy A., Perrin H., Porret R., Sempoux C., Chtioui H., Fraga M., Bart P.A., 2022. Gastro hep advances, 1 (4) pp. 601-603. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_5E2F0FB82317]
 
Safety, tolerability and pharmacokinetic profile of Macozinone (PBTZ169) formulated as native crystal powder: multiple ascendingdoses, phase-Ib trial in healthy volunteers
Chtioui H., Prod'Hom S., Desfontaine V., André P., Moulfi F., Bardinet C., Abo-Loha C., Tessieras J., Rothuizen L.E., Diezi L. et al., 2022. dans 15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT) - June 2022 Athens. European Journal of Clinical Pharmacology, 2022, 78: 1-163.
[serval:BIB_F1F116FD908F]
 
Safety, tolerability, pharmacokinetic profile and ex-vivo antitubercular acativity of macozinone formulated as spraydredi dispersion (SDD) versus native crystal powder (NCO?: single ascending doses, randomized, placebo-controlled, cross-ouver phase la trial in healthy volunteers
Rothuizen L.E., Ciullini L., Huser-Pitteloud J., Guidi M., Chtioui H., Ivanyuk A., André P., Bardinet C., Decosterd L.A., Spaggiari D. et al., 2022. dans SGAIM/SSMIG 6th Spring Congress Lausanne, June 2022. Primary and Hospital Care 2022: 22 (Suppl. 12), 173.
[serval:BIB_B502CD64B984]
2021
 
Spontaneous Partial Remission in a Child With B-Lineage Acute Lymphoblastic Leukemia and Chickenpox: A Role For Acyclovir?
Chtioui H., Ceppi F., Renella R., Diezi M., 2021/07/01. Journal of pediatric hematology/oncology, 43 (5) pp. e711-e714. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4886CE725DDF]
Case Report: Colchicine Toxicokinetic Analysis in a Poisoned Child Requiring Extracorporeal Life Support.
Pérez Marín M., Prod'hom S., de Villiers S.F., Ferry T., Amiet V., Natterer J., Perez M.H., Buclin T., Chtioui H., Longchamp D., 2021. Frontiers in pediatrics, 9 p. 658347. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D8ECE281A973]
2020
Hepatocellular type II fibrinogen inclusions in a patient with severe COVID-19 and hepatitis.
Fraga M., Moradpour D., Artru F., Romailler E., Tschopp J., Schneider A., Chtioui H., Neerman-Arbez M., Casini A., Alberio L. et al., 2020/10. Journal of hepatology, 73 (4) pp. 967-970. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B2C6A0D6E007]
2019
Combined immune checkpoint inhibitor therapy with nivolumab and ipilimumab causing acute-onset type 1 diabetes mellitus following a single administration: two case reports.
Zezza M., Kosinski C., Mekoguem C., Marino L., Chtioui H., Pitteloud N., Lamine F., 2019/12/23. BMC endocrine disorders, 19 (1) p. 144. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CB7AD473C23D]
 
High concentration of plasma methoxytyramine: dopamine-producing tumour or Parkinson's disease therapy?
Chtioui H., Sadowski S.M., Winzeler B., Tschopp O., Grouzmann E., Abid K., 2019/07. Annals of clinical biochemistry, 56 (4) pp. 466-471. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_50EB460BE1AC]
 
Défis dans la prise en charge du diabète en hémodialyse chronique [Challenges in managing diabetes in chronic hemodialysis]
Lamine F., Chtioui H., Schwotzer N., Pruijm M., Nobre D., Phan O., Ammor N., Andrey M., Grangier-Bernard P., Zanchi A., 2019/05/29. Revue medicale suisse, 15 (653) pp. 1132-1139. Peer-reviewed.
[Pmid][serval:BIB_3C34A5DC9916]
Sofosbuvir add-on to ribavirin for chronic hepatitis E in a cirrhotic liver transplant recipient: a case report.
Fraga M., Gouttenoire J., Sahli R., Chtioui H., Marcu C., Pascual M., Moradpour D., Vionnet J., 2019/05/24. BMC gastroenterology, 19 (1) p. 76. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_10FD0B1931C2]
 
Sub-picomolar quantification of PTH 1-34 in plasma by UHPLC-MS/MS after subcutaneous injection of teriparatide and identification of PTH 1-33, its degradation product.
Eugster P.J., Chtioui H., Herren A., Dunand M., Cappelle D., Bourquin J., Buclin T., Grouzmann E., 2019/03/20. Journal of pharmaceutical and biomedical analysis, 166 pp. 205-212. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4CDAF4AA5D52]
2018
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9AD89D587A49]
2017
 
OATP1B1 and DAA treatment for hepatitis C in patients with hepatocellular carcinoma.
Chtioui H., 2017/12. Hepatology, 66 (6) p. 2091. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F7349E17A46]
 
Pharmacokinetics of Pomalidomide in a Patient Receiving Hemodialysis Using a High-Cutoff Filter.
Dao K., Chtioui H., Lu Y., Peer C.J., Figg W.D., Pruijm M., Buclin T., Kissling S., 2017/04. American journal of kidney diseases, 69 (4) pp. 553-554. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0C3837BAEF06]
 
Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies
Bondallaz P., Chtioui H., Favrat B., Fornari E., Giroud C., Maeder P., 2017. pp. 379-390 dans Handbook of Cannabis and Related Pathologies chap. 39, Elsevier BV.
[DOI][WoS][serval:BIB_841EA21B373A]
2016
 
Cannabis and its effects on driving skills.
Bondallaz P., Favrat B., Chtioui H., Fornari E., Maeder P., Giroud C., 2016/11. Forensic science international, 268 pp. 92-102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7667A10BF648]
 
Pharmacovigilance [Pharmacovigilance update]
Dao K., Chtioui H., Rothuizen L.E., Diezi L., Prod'hom S., Winterfeld U., Buclin T., Livio F., 2016/01/13. Revue medicale suisse, 12 (500) pp. 75-79.
[Pmid][serval:BIB_61D54069EC5E]
 
Therapeutic drug monitoring for sofosbuvir and daclatasvir in transplant recipients with chronic hepatitis C and advanced renal disease.
Vionnet J., Saouli A.C., Pascual M., Stucker F., Decosterd L.A., Moradpour D., Chtioui H., 2016. Journal of Hepatology, 65 (5) pp. 1063-1065. Peer-reviewed.
[DOI][Pmid][serval:BIB_D327874A3973]
2015
 
Pharmacokinetics in hepatic impairment: Mind the protein binding.
Chtioui H., Buclin T., 2015. Journal of Hepatology, 63 (6) pp. 1539-1540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_57D522F33942]
 
Pharmacovigilance [Pharmacovigilance update].
Fogarasi Szabo N., Diezi L., Delenclos L., Renard D., Chtioui H., Rothuizen L.E., Buclin T., Livio F., 2015/01. Revue Médicale Suisse, 11 (456-457) pp. 124-128.
[URN][Pmid][serval:BIB_D8A2874AB9AF]
Sofosbuvir and ribavirin before liver re-transplantation for graft failure due to recurrent hepatitis C: a case report.
Vionnet J., Pascual M., Chtioui H., Giostra E., Majno P.E., Decosterd L.A., Moradpour D., 2015. BMC Gastroenterology, 15 (1) p. 38. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2416C6CBDE27]
2014
 
Nouveaux traitements de l'hépatite C: aspects pharmacologiques et potentiel d'interaction [New hepatitis C treatments: pharmacological considerations and potential for drug interactions].
Chtioui H., Buclin T., Moradpour D., 2014/09. Revue Médicale Suisse, 10 (440) pp. 1600-4, 1606.
[URN][Pmid][serval:BIB_137CFB3E0910]
Long-term effects of cannabis on brain structure.
Battistella G., Fornari E., Annoni J.M., Chtioui H., Dao K., Fabritius M., Favrat B., Mall J.F., Maeder P., Giroud C., 2014/08. Neuropsychopharmacology, 39 (9) pp. 2041-2048. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_14EC6BEB80DF]
 
Fitness to drive and cannabis: Experimental and real-life case study validation of two blood THCCOOH thresholds to distinguish occasional users from heavy smokers
Giroud C., Fabritius M., Augsburger M., Chtioui H., Favrat B., 2014. pp. S20 dans Analytical, Clinical and Forensic Toxicology International Meeting, Toxicologie Analytique et Clinique.
[DOI][serval:BIB_F335ECC92BD4]
 
Fitness to drive and cannabis: Validation of two blood THCCOOH thresholds to distinguish occasional users from heavy smokers.
Fabritius M., Augsburger M., Chtioui H., Favrat B., Giroud C., 2014. Forensic Science International, 242 pp. 1-8. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_084A609F03F9]
2013
 
THCCOOH concentrations in whole blood: are they useful in discriminating occasional from heavy smokers?
Fabritius M., Favrat B., Chtioui H., Battistella G., Annoni J.M., Appenzeller M., Dao K., Fornari E., Lauer E., Mall J.F. et al., 2013/10/31. Drug testing and analysis, 6 (1-2) pp. 155-163. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_476BC61913C2]
Intravenous streptomycin dosing regimen in a patient undergoing hemodialysis: Plasma level monitoring and pharmacokinetic simulation
Chtioui H., Zbinden D., Manuel O., Entenza J., Decosterd L.A., Buclin T., 2013/08. pp. e106 dans 11th Conference of the European Association for Clinical Pharmacology and Therapeutics, Clinical Therapeutics.
[URN][DOI][serval:BIB_7147B1F82056]
Comparison of cannabinoid concentrations in oral fluid and whole blood between occasional and regular cannabis smokers prior to and after smoking a cannabis joint.
Fabritius M., Chtioui H., Battistella G., Annoni J.M., Dao K., Favrat B., Fornari E., Lauer E., Maeder P., Giroud C., 2013. Analytical and Bioanalytical Chemistry, 405 (30) pp. 9791-9803.
[URN][DOI][WoS][Pmid][serval:BIB_F01DAEEAD312]
Weed or wheel! FMRI, behavioural, and toxicological investigations of how cannabis smoking affects skills necessary for driving.
Battistella G., Fornari E., Thomas A., Mall J.F., Chtioui H., Appenzeller M., Annoni J.M., Favrat B., Maeder P., Giroud C., 2013/01. Plos One, 8 (1) pp. e52545. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EF6F5D1419B9]
2011
 
Teriparatide therapy for osteonecrosis of the jaw.
Chtioui H., Lamine F., Daghfous R., 2011/03/17. The New England journal of medicine, 364 (11) pp. 1081-2; author reply 1082. Peer-reviewed.
[DOI][Pmid][serval:BIB_A98C00D2F74B]
2010
 
Macro-AST in an asymptomatic young patient.
Chtioui H., Mauerhofer O., Günther B., Dufour J.F., 2010. Annals of hepatology, 9 (1) pp. 93-95. Peer-reviewed.
[Pmid][serval:BIB_BA1CAE06E7C6]
 
Plasma and urine profiles of Delta9-tetrahydrocannabinol and its metabolites 11-hydroxy-Delta9-tetrahydrocannabinol and 11-nor-9-carboxy-Delta9-tetrahydrocannabinol after cannabis smoking by male volunteers to estimate recent consumption by athletes.
Brenneisen R., Meyer P., Chtioui H., Saugy M., Kamber M., 2010. Analytical and Bioanalytical Chemistry, 396 (7) pp. 2493-2502. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_45ACB61BAE86]
2009
 
Concomitant treatment with lamivudine renders cladribine inactive by inhibition of its phosphorylation.
Chtioui H., Millius C., Lämmle B., Lauterburg B.H., 2009/01. British journal of haematology, 144 (1) pp. 136-137. Peer-reviewed.
[DOI][Pmid][serval:BIB_D42DCB9F064B]
 
Interactions médicamenteuses dans le traitement de la douleur
Chtioui H., Tamches E., 2009. Dolor 09.2 pp. 1-4.
[serval:BIB_8079D9489E01]
2007
 
Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis.
Chtioui H., Semela D., Ledermann M., Zimmermann A., Dufour J.F., 2007/08. Liver international : official journal of the International Association for the Study of the Liver, 27 (6) pp. 764-771. Peer-reviewed.
[DOI][Pmid][serval:BIB_CA37D046B1A6]
 
The Textbook of Hepatology: From Basic Science to Clinical Practice; Section 14 Toxic liver injury -Hepatic injury due to physical agents-
Lauterburg B.H., Chtioui H, 2007/06., Blackwell Publishing.
[serval:BIB_68E54B92D17C]
2006
 
Cellular immunity in healthy volunteers treated with an octavalent conjugate Pseudomonas aeruginosa vaccine.
Zuercher A.W., Imboden M.A., Jampen S., Bosse D., Ulrich M., Chtioui H., Lauterburg B.H., Lang A.B., 2006. Clinical and Experimental Immunology, 143 (1) pp. 132-138. Peer-reviewed.
[DOI][Pmid][serval:BIB_ED5A89805A38]
2005
 
Cellular immunity in healthy volunteers treated with an octavalent conjugate Pseudomonas aeruginosa vaccine.
Zuercher A.W., Imboden M.A., Jampen S., Bosse D., Ulrich M., Chtioui H., Lauterburg B.H., Lang A.B., 2005/11. Clinical and experimental immunology, 142 (2) pp. 381-387. Peer-reviewed.
[DOI][Pmid][serval:BIB_A2BB8B972E45]
 
Unusual evolution of posterior reversible encephalopathy syndrome (PRES) one year after liver transplantation.
Chtioui H., Zimmermann A., Dufour J.F., 2005/05. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 11 (5) pp. 588-590.
[DOI][Pmid][serval:BIB_6ECE5164A5E4]
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