Christine Sempoux

Publications | Mémoires et thèses

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360 publications

Sous presse | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | ...
 
Hyperthermic intrathoracic chemotherapy modulates the immune microenvironment of pleural mesothelioma and improves the impact of dual immune checkpoint inhibition.
Hao Y., Gkasti A., Managh A.J., Dagher J., Sifis A., Tiron L., Chriqui L.E., Marie D.N., De Souza Silva O., Christodoulou M. et al. Cancer immunology research. Peer-reviewed.
 
Rare primary liver cancers: An EASL position paper.
Wege H., Campani C., de Kleine R., Meyer T., Nault J.C., Pawlik T.M., Reig M., Ricke J., Sempoux C., Torzilli G. et al. Journal of hepatology. Peer-reviewed.
 
Editorial for "Beta-Catenin-Mutated Hepatocellular Adenomas at Hepatobiliary Phase MRI: A Systematic Review and Meta-Analysis".
Schmidt S., Sempoux C., 2024/11. Journal of magnetic resonance imaging, 60 (5) pp. 2115-2116. Peer-reviewed.
PD-L1 expression, tumor-infiltrating lymphocytes, and mismatch repair proteins status in digestive neuroendocrine neoplasms: exploring their potential role as theragnostic and prognostic biomarkers.
Multone E., La Rosa S., Sempoux C., Uccella S., 2024/11. Virchows Archiv, 485 (5) pp. 841-851. Peer-reviewed.
 
Maladie hépatique associée à la chirurgie de Fontan [Fontan associated liver disease]
Shams T., Salvador Nunes L., Schmidt S., Gast E., Sempoux C., Moradpour D., Di Bernardo S., Sekarski N., Rutz T., Ladouceur M. et al., 2024/08/28. Revue medicale suisse, 20 (884) pp. 1469-1475. Peer-reviewed.
Spatial transcriptomics profiling of gallbladder adenocarcinoma: a detailed two-case study of progression from precursor lesions to cancer.
Pirenne S., Manzano-Núñez F., Loriot A., Cordi S., Desmet L., Aydin S., Hubert C., Toffoli S., Limaye N., Sempoux C. et al., 2024/08/20. BMC cancer, 24 (1) p. 1025. Peer-reviewed.
High prevalence of short telomeres in idiopathic porto-sinusoidal vascular disorder.
Coukos A., Saglietti C., Sempoux C., Haubitz M., Greuter T., Mittaz-Crettol L., Maurer F., Mdawar-Bailly E., Moradpour D., Alberio L. et al., 2024/08/01. Hepatology communications, 8 (8). Peer-reviewed.
Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors and CAR-T Cell Therapy: A Comprehensive Imaging-Based Review.
Pozzessere C., Mazini B., Omoumi P., Jreige M., Noirez L., Digklia A., Fasquelle F., Sempoux C., Dromain C., 2024/07/19. Cancers, 16 (14). Peer-reviewed.
 
Letter to the Editor There are benefits of subtyping hepatocellular adenoma also in men. Following-up on the publication by González IA et al. Clinicopathologic characterization of hepatocellular adenomas in men: A multicenter experience. Hum Pathol. 2023.
Sempoux C., Balabaud C., Gouw A.S., Bioulac-Sage P., 2024/07. Human pathology, 149 pp. 77-78. Peer-reviewed.
 
Sonic hedgehog hepatocellular adenoma: magnetic resonance imaging features and correlation with histology.
Ducatel A., Trillaud H., Reizine E., Vilgrain V., Sempoux C., Schmidt-Kobbe S., Gouw ASH, de Haas R.J., Julien C., Paradis V. et al., 2024/07. European radiology, 34 (7) pp. 4649-4662. Peer-reviewed.
Increased [<sup>68</sup>Ga]Ga-SST uptake in the uncinate pancreatic process in new digital PET/CT machine and potential association with clinical and histologic factors in NET patients.
Firsova M., Treglia G., Sempoux C., Dromain C., Prior J.O., Schaefer N., Boughdad S., 2024/06/24. EJNMMI reports, 8 (1) p. 18. Peer-reviewed.
 
Primary hepatocellular carcinoma of the spleen.
Saglietti C., Fasquelle F., Barcena C., Schmidt S., Shirata C., Uldry E., Halkic N., Sempoux C., 2024/06. Pathology, 56 (4) pp. 600-601. Peer-reviewed.
The enigma of glutamine synthetase and b-catenin expression in hepatocellular adenoma in familial adenomatous polyposis coli.
Gouw ASH, Sempoux C., Bioulac-Sage P., 2024/04. Virchows Archiv, 484 (4) pp. 553-554. Peer-reviewed.
 
Closing the scissor-shaped curve: Strategies to promote gender equality in academia.
Joyce J.A., Masina S., Michalik L., Pot C., Sempoux C., Amati F., 2024/03/14. Cell, 187 (6) pp. 1335-1342. Peer-reviewed.
 
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanoma.
Barras D., Ghisoni E., Chiffelle J., Orcurto A., Dagher J., Fahr N., Benedetti F., Crespo I., Grimm A.J., Morotti M. et al., 2024/02/02. Science immunology, 9 (92) pp. eadg7995. Peer-reviewed.
 
Prospective evaluation of MR-TRG (Tumor Regression Grade) in esophageal cancer after neo-adjuvant therapy: Preliminary results.
Chapellier P., Fasquelle F., Saglietti C., Kinj R., Mantziari S., Schäfer M., Haefliger L., Jreige M., Vietti Violi N., Sempoux C. et al., 2024/02. European journal of radiology, 171 p. 111263. Peer-reviewed.
Cohort Profile Update: The Swiss Eosinophilic Esophagitis Cohort Study (SEECS).
El-Khoury J.W., Safroneeva E., Saner C., Rossel J.B., Trelle S., Zwahlen M., Biedermann L., Kreienbuehl A., Greuter T., Schreiner P. et al., 2024. Inflammatory intestinal diseases, 9 (1) pp. 165-173. Peer-reviewed.
Macroscopic Characterization of Hepatocellular Carcinoma: An Underexploited Source of Prognostic Factors.
Gonvers S., Martins-Filho S.N., Hirayama A., Calderaro J., Phillips R., Uldry E., Demartines N., Melloul E., Park Y.N., Paradis V. et al., 2024. Journal of hepatocellular carcinoma, 11 pp. 707-719. Peer-reviewed.
Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma.
Calderaro J., Ghaffari Laleh N., Zeng Q., Maille P., Favre L., Pujals A., Klein C., Bazille C., Heij L.R., Uguen A. et al., 2023/12/14. Nature communications, 14 (1) p. 8290. Peer-reviewed.
 
Artificial intelligence-based pathology as a biomarker of sensitivity to atezolizumab-bevacizumab in patients with hepatocellular carcinoma: a multicentre retrospective study.
Zeng Q., Klein C., Caruso S., Maille P., Allende D.S., Mínguez B., Iavarone M., Ningarhari M., Casadei-Gardini A., Pedica F. et al., 2023/12. The Lancet. Oncology, 24 (12) pp. 1411-1422. Peer-reviewed.
 
In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A., Vílchez-Acosta A., Desdín-Micó G., Picó S., Mrabti C., Montenegro-Borbolla E., Maroun C.Y., Haghani A., Brooke R., Del Carmen Maza M. et al., 2023/12. Nature aging, 3 (12) pp. 1509-1520. Peer-reviewed.
 
An Unusual Cause of Severe Granulomatous Hepatitis and Jaundice.
Coukos A., Uldry E., Meylan S., Schmidt S., Fasquelle F., Sempoux C., Fraga M., 2023/11/01. The American journal of gastroenterology, 118 (11) p. 1920. Peer-reviewed.
 
Biliary Tract Cancer: Molecular Biology of Precursor Lesions.
Manzano-Núñez F., Prates Tiago Aguilar L., Sempoux C., Lemaigre F.P., 2023/11. Seminars in liver disease, 43 (4) pp. 472-484. Peer-reviewed.
Impact of positive microscopic resection margins (R1) after gastrectomy in diffuse-type gastric cancer.
Gaspar-Figueiredo S., Allemann P., Borgstein ABJ, Joliat G.R., Luzuy-Guarnero V., Brunel C., Sempoux C., Gisbertz S.S., Demartines N., van Berge Henegouwen M.I. et al., 2023/10. Journal of cancer research and clinical oncology, 149 (13) pp. 11105-11115. Peer-reviewed.
Elevated liver function tests in a patient with breast cancer.
Neftel C., Zaman K., Chtioui H., Moradpour D., Sempoux C., Fraga M., 2023/09. Journal of hepatology, 79 (3) pp. e109-e111. Peer-reviewed.
 
Pathological features in non-neoplastic congenital and adult hyperinsulinism: from nesidioblastosis to current terminology and understanding.
Sempoux C., Klöppel G., 2023/09/01. Endocrine-related cancer, 30 (9) pp. e230034. Peer-reviewed.
MDCT-findings in patients with non-occlusive mesenteric ischemia (NOMI): influence of vasoconstrictor agents.
Topolsky A., Pantet O., Liaudet L., Sempoux C., Denys A., Knebel J.F., Schmidt S., 2023/05. European radiology, 33 (5) pp. 3627-3637. Peer-reviewed.
Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features.
Haefliger S., Hench J., O'Rourke C.J., Meyer-Schaller N., Uzun S., Saldarriaga J., Weber A., Mazzucchelli L., Jermann P., Frank S. et al., 2023/04. Histopathology, 82 (5) pp. 722-730. Peer-reviewed.
Programmed death-ligand1 is a determinant of recurrence in alveolar echinococcosis.
Joliat G.R., Martins-Filho S.N., Haefliger S., Demartines N., Halkic N., Labgaa Ismail, Sempoux C., 2023/04. International journal of infectious diseases, 129 pp. 285-288. Peer-reviewed.
Response to a letter to the editor: a better understanding of Immune Checkpoint Inhibitor-induced cholangitis for better management.
Coukos A., Vionnet J., Sempoux C., Fraga M., 2023/02. Journal for immunotherapy of cancer, 11 (2) pp. e006877. Peer-reviewed.
Immunohistochemistry for hepatitis E virus capsid protein cross-reacts with cytomegalovirus-infected cells: a potential diagnostic pitfall.
Lenggenhager D., Grossmann J., Gouttenoire J., Sempoux C., Weber A., 2023/01. Histopathology, 82 (2) pp. 354-358. Peer-reviewed.
 
Nestin as a diagnostic and prognostic marker for combined hepatocellular-cholangiocarcinoma.
Calderaro J., Di Tommaso L., Maillé P., Beaufrère A., Nguyen C.T., Heij L., Gnemmi V., Graham R.P., Charlotte F., Chartier S. et al., 2022/12. Journal of hepatology, 77 (6) pp. 1586-1597. Peer-reviewed.
Women with Cervical High-Risk Human Papillomavirus: Be Aware of Your Anus! The ANGY Cross-Sectional Clinical Study.
Jacot-Guillarmod M., Balaya V., Mathis J., Hübner M., Grass F., Cavassini M., Sempoux C., Mathevet P., Pache B., 2022/10/18. Cancers, 14 (20) p. 5096. Peer-reviewed.
Porto-sinusoidal vascular disorder.
De Gottardi A., Sempoux C., Berzigotti A., 2022/10. Journal of hepatology, 77 (4) pp. 1124-1135. Peer-reviewed.
Systematic comparison with autoimmune liver disease identifies specific histological features of immune checkpoint inhibitor-related adverse events.
Coukos A., Vionnet J., Obeid M., Bouchaab H., Peters S., Latifyan S., Wicky A., Michielin O., Chtioui H., Moradpour D. et al., 2022/10. Journal for immunotherapy of cancer, 10 (10) pp. e005635. Peer-reviewed.
Towards a national strategy for digital pathology in Switzerland.
Janowczyk A., Baumhoer D., Dirnhofer S., Grobholz R., Kipar A., de Leval L., Merkler D., Michielin O., Moch H., Perren A. et al., 2022/10. Virchows Archiv, 481 (4) pp. 647-652. Peer-reviewed.
MiR-22 Deficiency Fosters Hepatocellular Carcinoma Development in Fatty Liver.
Gjorgjieva M., Ay A.S., Correia de Sousa M., Delangre E., Dolicka D., Sobolewski C., Maeder C., Fournier M., Sempoux C., Foti M., 2022/09/14. Cells, 11 (18) p. 2860. Peer-reviewed.
 
Clinical, histological and molecular profiling of different stages of alcohol-related liver disease.
Ventura-Cots M., Argemi J., Jones P.D., Lackner C., El Hag M., Abraldes J.G., Alvarado E., Clemente A., Ravi S., Alves A. et al., 2022/09. Gut, 71 (9) pp. 1856-1866. Peer-reviewed.
Syndrome des télomères courts chez l’adulte : une entité rare qu’il faut savoir évoquer [Short telomere syndrome in adults: a rare entity that should be evoked]
Coukos A., Daccord C., Lazor R., Blum S., Naveiras O., Unger S., Vionnet J., Gaide O., Koutsokera A., Moschouri E. et al., 2022/08/31. Revue medicale suisse, 18 (793) pp. 1606-1613. Peer-reviewed.
Portal vein recanalisation alone to treat severe portal hypertension in non-cirrhotic patients with chronic extrahepatic portal vein obstruction.
Artru F., Vietti-Violi N., Sempoux C., Vieira Barbosa J., Becce F., Sah N., Marot A., Deltenre P., Moschouri E., Fraga M. et al., 2022/08. JHEP reports, 4 (8) p. 100511. Peer-reviewed.
Etiology, Pathogenesis, Diagnosis, and Practical Implications of Hepatocellular Neoplasms.
Hytiroglou P., Bioulac-Sage P., Theise N.D., Sempoux C., 2022/07/28. Cancers, 14 (15) p. 3670. Peer-reviewed.
Ampullary Neuroendocrine Neoplasms: Identification of Prognostic Factors in a Multicentric Series of 119 Cases.
Vanoli A., Grami O., Klersy C., Milanetto A.C., Albarello L., Fassan M., Luchini C., Grillo F., Spaggiari P., Inzani F. et al., 2022/06. Endocrine pathology, 33 (2) pp. 274-288. Peer-reviewed.
Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth.
Bernier-Latmani J., Cisarovsky C., Mahfoud S., Ragusa S., Dupanloup I., Barras D., Renevey F., Nassiri S., Anderle P., Squadrito M.L. et al., 2022/05. Nature cardiovascular research, 1 (5) pp. 476-490. Peer-reviewed.
Hepatocellular adenoma: what we know, what we do not know, and why it matters.
Bioulac-Sage P., Gouw ASH, Balabaud C., Sempoux C., 2022/05. Histopathology, 80 (6) pp. 878-897. Peer-reviewed.
TIA1 Loss Exacerbates Fatty Liver Disease but Exerts a Dual Role in Hepatocarcinogenesis.
Dolicka D., Zahoran S., Correia de Sousa M., Gjorgjieva M., Sempoux C., Fournier M., Maeder C., Collart M.A., Foti M., Sobolewski C., 2022/03/27. Cancers, 14 (7) p. 1704. Peer-reviewed.
EBV-positive large B-cell lymphoma with an unusual intravascular presentation and associated haemophagocytic syndrome in an HIV-positive patient: report of a case expanding the spectrum of EBV-positive immunodeficiency-associated lymphoproliferative disorders.
Veloza L., Tsai C.Y., Bisig B., Pantet O., Alberio L., Sempoux C., Cavassini M., de Leval L., 2022/03. Virchows Archiv, 480 (3) pp. 699-705. Peer-reviewed.
Role of immunohistochemistry for interobserver agreement of Peritoneal Regression Grading Score in peritoneal metastasis.
Detlefsen S., Windedal T., Bibeau F., Bruhn L.V., Carr N., Graversen M., Markowski K., Mortensen M.B., Neureiter D., Sempoux C. et al., 2022/02. Human pathology, 120 pp. 77-87. Peer-reviewed.
Bile acids contribute to the development of non-alcoholic steatohepatitis in mice.
Gillard J., Clerbaux L.A., Nachit M., Sempoux C., Staels B., Bindels L.B., Tailleux A., Leclercq I.A., 2022/01. JHEP reports, 4 (1) p. 100387. Peer-reviewed.
Histological regression of peritoneal metastases of recurrent tubo-ovarian cancer after systemic chemotherapy.
Pache B., Teixeira Farinha H., Toussaint L., Demartines N., Hastir D., Mathevet P., Sempoux C., Hübner M., 2022. Frontiers in surgery, 9 p. 936613. Peer-reviewed.
Iberogast®-Induced Acute Liver Injury-A Case Report.
Leroy A., Perrin H., Porret R., Sempoux C., Chtioui H., Fraga M., Bart P.A., 2022. Gastro hep advances, 1 (4) pp. 601-603. Peer-reviewed.
Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.
Herrera F.G., Ronet C., Ochoa de Olza M., Barras D., Crespo I., Andreatta M., Corria-Osorio J., Spill A., Benedetti F., Genolet R. et al., 2022/01. Cancer discovery, 12 (1) pp. 108-133. Peer-reviewed.
Partial lipodystrophy, severe dyslipidaemia and insulin resistant diabetes as early signs of Werner syndrome.
Atallah I., McCormick D., Good J.M., Barigou M., Fraga M., Sempoux C., Superti-Furga A., Semple R.K., Tran C., 2022. Journal of clinical lipidology, 16 (5) pp. 583-590. Peer-reviewed.
Prevalence of anal dysplasia and HPV genotypes in gynecology patients: The ANGY cross-sectional prospective clinical study protocol.
Pache B., Balaya V., Mathis J., Hübner M., Sahli R., Cavassini M., Sempoux C., Mathevet P., Jacot-Guillarmod M., 2022. PloS one, 17 (10) pp. e0276438. Peer-reviewed.
 
ASO Visual Abstract: The ‘Real R0': A Resection Margin < 0.1 cm is Associated with Poor Prognosis After Oncological Esophagectomy
St-Amour P., Winiker M., Sempoux C., Fasquelle F., Demartines N., Schäfer M., Mantziari S., 2021/12. Annals of Surgical Oncology, 28 (S3) pp. 497-498. Peer-reviewed.
The "Real R0": A Resection Margin Smaller Than 0.1 cm is Associated with a Poor Prognosis After Oncologic Esophagectomy.
St-Amour P., Winiker M., Sempoux C., Fasquelle F., Demartines N., Schäfer M., Mantziari S., 2021/11. Annals of surgical oncology, 28 (12) pp. 7095-7106. Peer-reviewed.
Focal nodular hyperplasia associated with a giant hepatocellular adenoma: A case report and review of literature.
Gaspar-Figueiredo S., Kefleyesus A., Sempoux C., Uldry E., Halkic N., 2021/10/27. World journal of hepatology, 13 (10) pp. 1450-1458. Peer-reviewed.
Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis.
Correia de Sousa M., Calo N., Sobolewski C., Gjorgjieva M., Clément S., Maeder C., Dolicka D., Fournier M., Vinet L., Montet X. et al., 2021/10/04. Cancers, 13 (19) p. 4983. Peer-reviewed.
Increasing Incidence of Microscopic Colitis in a Population-Based Cohort Study in Switzerland.
Maye H., Safroneeva E., Godat S., Sempoux C., Yan P., Bouzourène H., Seelentag W., Stauffer E., Taminelli L., Seibold F. et al., 2021/10. Clinical gastroenterology and hepatology, 19 (10) pp. 2205-2206. Peer-reviewed.
Histological regression of gastrointestinal peritoneal metastases after systemic chemotherapy.
Toussaint L., Teixeira Farinha H., Barras J.L., Demartines N., Sempoux C., Hübner M., 2021/09. Pleura and peritoneum, 6 (3) pp. 113-119. Peer-reviewed.
Hépatite autoimmune : mise au point 2021 [Autoimmune hepatitis: 2021 update]
Stamm G.M., Sempoux C., Fraga M., Comte D., Aubert V., Moradpour D., Vionnet J., Moschouri E., 2021/09/01. Revue medicale suisse, 17 (748) pp. 1457-1463. Peer-reviewed.
 
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy.
Siwicki M., Gort-Freitas N.A., Messemaker M., Bill R., Gungabeesoon J., Engblom C., Zilionis R., Garris C., Gerhard G.M., Kohl A. et al., 2021/07/02. Science immunology, 6 (61) pp. eabi7083. Peer-reviewed.
CD73 expression in normal, hyperplastic, and neoplastic thyroid: a systematic evaluation revealing CD73 overexpression as a feature of papillary carcinomas.
Monteiro I., Missiaglia E., Sciarra A., Santos J.V., Bouilly J., Romero P., Sempoux C., de Leval L., 2021/07. Virchows Archiv, 479 (1) pp. 209-214. Peer-reviewed.
 
Hepatocellular adenomas: the expanding epidemiology.
Brunt E.M., Sempoux C., Bioulac-Sage P., 2021/07. Histopathology, 79 (1) pp. 20-22. Peer-reviewed.
 
Ictère: recherche de l'agent coupable!
Bennani Alice, Kraege Vanessa, Sempoux Christine, Sartori Claudio, 2021/06/22. Forum Médical Suisse ‒ Swiss Medical Forum, 21 (2526) pp. 441-445. Peer-reviewed.
Rate of Freeze Impacts the Survival and Immune Responses Post Cryoablation of Melanoma.
Yakkala C., Dagher J., Sempoux C., Chiang C.L., Denys A., Kandalaft L.E., Koppolu B., Duran R., 2021/06/03. Frontiers in immunology, 12 p. 695150. Peer-reviewed.
 
Immune cell infiltration in colonic cancer: correlation between biopsy and surgical specimens.
Bordry N., Germann M., Foukas P.G., Sempoux C., Yan P., Dormond O., Speiser D.E., Demartines N., Sauvain M.O., 2021/04/30. The British journal of surgery, 108 (4) pp. 346-350. Peer-reviewed.
Autochthonous hepatitis E as a cause of acute-on-chronic liver failure and death: histopathology can be misleading but transaminases may provide a clue.
Vieira Barbosa J., Müllhaupt B., Brunner F., Filipowicz Sinnreich M., Semela D., Montani M., Cathomas G., Neuweiler J., Gouttenoire J., Artru F. et al., 2021/04/26. Swiss medical weekly, 151 pp. w20502. Peer-reviewed.
Predictive Patterns of Glutamine Synthetase Immunohistochemical Staining in CTNNB1-mutated Hepatocellular Adenomas.
Sempoux C., Gouw ASH, Dunet V., Paradis V., Balabaud C., Bioulac-Sage P., 2021/04/01. The American journal of surgical pathology, 45 (4) pp. 477-487. Peer-reviewed.
Reproducibility of tumor budding assessment in pancreatic cancer based on a multicenter interobserver study.
Karamitopoulou E., Esposito I., Zlobec I., Insilla A.C., Wartenberg M., Schaeffer D.F., Kalloger S., La Rosa S., Sempoux C., Ramos Centeno I. et al., 2021/04. Virchows Archiv, 478 (4) pp. 719-726. Peer-reviewed.
 
Solute carrier family 12 member 2 as a proteomic and histological biomarker of dysplasia and neoplasia in ulcerative colitis.
Merli A.M., Vieujean S., Massot C., Blétard N., Quesada Calvo F., Baiwir D., Mazzucchelli G., Servais L., Wéra O., Oury C. et al., 2021/02/28. Journal of Crohn's & colitis, 15 (2) pp. 287–298. Peer-reviewed.
Personalized Cytokine-Directed Therapy With Tocilizumab for Refractory Immune Checkpoint Inhibitor-Related Cholangiohepatitis.
Moi L., Bouchaab H., Mederos N., Nguyen-Ngoc T., Perreau M., Fenwick C., Vaucher J., Sempoux C., Peters S., Obeid M., 2021/02. Journal of thoracic oncology, 16 (2) pp. 318-326. Peer-reviewed.
Prediction of tumour grade and survival outcome using pre-treatment PET- and MRI-derived imaging features in patients with resectable pancreatic ductal adenocarcinoma.
Dunet V., Halkic N., Sempoux C., Demartines N., Montemurro M., Prior J.O., Schmidt S., 2021/02. European radiology, 31 (2) pp. 992-1001. Peer-reviewed.
 
Autoimmune hepatitis as a sequelae of oxcarbazepine-induced drug reaction with eosinophilia and systemic symptoms.
Droz N., Chevrier F., Lapointe A.K., Sempoux C., Fraga M., Comte D., 2021/01. The journal of allergy and clinical immunology. In practice, 9 (1) pp. 580-581. Peer-reviewed.
Case Report: SARS-CoV-2 as an unexpected causal agent of predominant febrile hepatitis.
Filippidis P., van Ouwenaller F., Cerutti A., Geiger-Jacquod A., Sempoux C., Pantaleo G., Moradpour D., Lamoth F., 2021. F1000Research, 10 p. 400. Peer-reviewed.
The histologic presentation of hepatitis E reflects patients' immune status and pre-existing liver condition.
Lenggenhager D., Pawel S., Honcharova-Biletska H., Evert K., Wenzel J.J., Montani M., Furrer E., Fraga M., Moradpour D., Sempoux C. et al., 2021/01. Modern pathology, 34 (1) pp. 233-248. Peer-reviewed.
 
Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment.
Gannon P.O., Harari A., Auger A., Murgues C., Zangiacomi V., Rubin O., Ellefsen Lavoie K., Guillemot L., Navarro Rodrigo B., Nguyen-Ngoc T. et al., 2020/12. Cytotherapy, 22 (12) pp. 780-791. Peer-reviewed.
Incidence trends of lung and gastroenteropancreatic neuroendocrine neoplasms in Switzerland.
Alwan H., La Rosa S., Andreas Kopp P., Germann S., Maspoli-Conconi M., Sempoux C., Bulliard J.L., 2020/12. Cancer medicine, 9 (24) pp. 9454-9461. Peer-reviewed.
 
Histologic parameter score does not predict short-term survival in severe alcoholic hepatitis.
Dubois M., Sciarra A., Trépo E., Marot A., Saldarriaga J., Moreno C., Sempoux C., Deltenre P., 2020/11. United European gastroenterology journal, 8 (9) pp. 1003-1012. Peer-reviewed.
Hepatocellular type II fibrinogen inclusions in a patient with severe COVID-19 and hepatitis.
Fraga M., Moradpour D., Artru F., Romailler E., Tschopp J., Schneider A., Chtioui H., Neerman-Arbez M., Casini A., Alberio L. et al., 2020/10. Journal of hepatology, 73 (4) pp. 967-970. Peer-reviewed.
 
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development.
Sobolewski C., Abegg D., Berthou F., Dolicka D., Calo N., Sempoux C., Fournier M., Maeder C., Ay A.S., Clavien P.A. et al., 2020/10. Gut, 69 (10) pp. 1841-1854. Peer-reviewed.
Adénomes hépatocellulaires : update 2020 [Hepatocellular adenoma: update 2020]
Romailler E., Schmidt Kobbe S., Moradpour D., Sempoux C., 2020/09/02. Revue medicale suisse, 16 (704) pp. 1554-1559. Peer-reviewed.
 
Molecular classification and therapeutic targets in extrahepatic cholangiocarcinoma.
Montal R., Sia D., Montironi C., Leow W.Q., Esteban-Fabró R., Pinyol R., Torres-Martin M., Bassaganyas L., Moeini A., Peix J. et al., 2020/08. Journal of hepatology, 73 (2) pp. 315-327. Peer-reviewed.
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Moschouri E., Vionnet J., Giostra E., Daccord C., Lazor R., Sciarra A., Letovanec I., Sempoux C., Gonzalez M., Unger S. et al., 2020/06. Liver transplantation, 26 (6) pp. 840-844. Peer-reviewed.
Tumor response and outcome after reverse treatment for patients with synchronous colorectal liver metastasis: a cohort study.
Du Pasquier C., Roulin D., Bize P., Sempoux C., Rebecchini C., Montemurro M., Schäfer M., Halkic N., Demartines N., 2020/04/19. BMC surgery, 20 (1) p. 78. Peer-reviewed.
ASS1 Overexpression: A Hallmark of Sonic Hedgehog Hepatocellular Adenomas; Recommendations for Clinical Practice.
Sala M., Gonzales D., Leste-Lasserre T., Dugot-Senant N., Paradis V., Di Tommaso S., Dupuy J.W., Pitard V., Dourthe C., Sciarra A. et al., 2020/04/11. Hepatology communications, 4 (6) pp. 809-824. Peer-reviewed.
 
Malignant transformation of liver fatty acid binding protein-deficient hepatocellular adenomas: histopathologic spectrum of a rare phenomenon.
Putra J., Ferrell L.D., Gouw ASH, Paradis V., Rishi A., Sempoux C., Balabaud C., Thung S.N., Bioulac-Sage P., 2020/04. Modern pathology, 33 (4) pp. 665-675. Peer-reviewed.
Gallbladder Mixed Neuroendocrine-Non-neuroendocrine Neoplasm (MiNEN) Arising in Intracholecystic Papillary Neoplasm: Clinicopathologic and Molecular Analysis of a Case and Review of the Literature.
Sciarra A., Missiaglia E., Trimech M., Melloul E., Brouland J.P., Sempoux C., La Rosa S., 2020/03. Endocrine pathology, 31 (1) pp. 84-93. Peer-reviewed.
Updates in the diagnosis of combined hepatocellular-cholangiocarcinoma.
Sciarra A., Park Y.N., Sempoux C., 2020/02. Human pathology, 96 pp. 48-55. Peer-reviewed.
Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβ.
Germann M., Zangger N., Sauvain M.O., Sempoux C., Bowler A.D., Wirapati P., Kandalaft L.E., Delorenzi M., Tejpar S., Coukos G. et al., 2020/01/09. EMBO molecular medicine, 12 (1) pp. e10681. Peer-reviewed.
Donor-specific antibodies in liver transplantation.
Vionnet J., Sempoux C., Pascual M., Sánchez-Fueyo A., Colmenero J., 2020/01. Gastroenterologia y hepatologia, 43 (1) pp. 34-45. Peer-reviewed.
Acinar cell carcinoma of the pancreas with thyroid-like follicular features: first description of a new diagnostic challenging subtype.
Saglietti C., Schneider V., Bongiovanni M., Missiaglia E., Bisig B., Dorta G., Demartines N., Sempoux C., La Rosa S., 2019/12. Virchows Archiv, 475 (6) pp. 789-794. Peer-reviewed.
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma.
Sarivalasis A., Boudousquié C., Balint K., Stevenson B.J., Gannon P.O., Iancu E.M., Rossier L., Martin Lluesma S., Mathevet P., Sempoux C. et al., 2019/11/26. Journal of translational medicine, 17 (1) p. 391. Peer-reviewed.
Synchronous tumors of the pancreas and the gallbladder: a case report with targeted NGS evaluation.
Sivade A., Sempoux C., Voutsadakis I., Brunel C., Halkic N., Godat S., Duran R., Digklia A., 2019/11. Annals of translational medicine, 7 (22) p. 696. Peer-reviewed.
ABC des polypes coliques [Abecedary of colonic polyps]
Archanioti P., Bornand A., Sempoux C., Unger S., Schoepfer A., Robert M., David G., 2019/08/28. Revue medicale suisse, 15 (660) pp. 1483-1487. Peer-reviewed.
Syndrome d’Alagille [Alagille Syndrome]
Wakim El-Khoury J., Venetz J.P., Rutz T., Sciarra A., Unger S., Sempoux C., Moradpour D., Fraga M., 2019/08/28. Revue medicale suisse, 15 (660) pp. 1506-1510. Peer-reviewed.
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients
Bassani-Sternberg Michal, Digklia Antonia, Huber Florian, Wagner Dorothea, Sempoux Christine, Stevenson Brian J., Thierry Anne-Christine, Michaux Justine, Pak HuiSong, Racle Julien et al., 2019/08/08. Frontiers in Immunology, 10 p. 1832. Peer-reviewed.
Invasive Ductular Reaction Operates Hepatobiliary Junctions upon Hepatocellular Injury in Rodents and Humans.
Clerbaux L.A., Manco R., Van Hul N., Bouzin C., Sciarra A., Sempoux C., Theise N.D., Leclercq I.A., 2019/08. The American journal of pathology, 189 (8) pp. 1569-1581. Peer-reviewed.
 
Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence?
Haefliger S., Milowich D., Sciarra A., Trimeche M., Bouilly J., Kaiser J., Volpi S., Brouland J.P., Sempoux C., de Leval L., 2019/06. Annals of hematology, 98 (6) pp. 1513-1516. Peer-reviewed.
 
Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.
Manco R., Clerbaux L.A., Verhulst S., Bou Nader M., Sempoux C., Ambroise J., Bearzatto B., Gala J.L., Horsmans Y., van Grunsven L. et al., 2019/06. Journal of hepatology, 70 (6) pp. 1180-1191. Peer-reviewed.
Reproducibility of the peritoneal regression grading score for assessment of response to therapy in peritoneal metastasis.
Solass W., Sempoux C., Carr N.J., Bibeau F., Neureiter D., Jäger T., Di Caterino T., Brunel C., Klieser E., Fristrup C.W. et al., 2019/06. Histopathology, 74 (7) pp. 1014-1024. Peer-reviewed.
CD73 expression in normal and pathological human hepatobiliopancreatic tissues.
Sciarra A., Monteiro I., Ménétrier-Caux C., Caux C., Gilbert B., Halkic N., La Rosa S., Romero P., Sempoux C., de Leval L., 2019/03. Cancer immunology, immunotherapy, 68 (3) pp. 467-478. Peer-reviewed.
 
Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Sciarra Amedeo, Monteiro Inês, Ménétrier-Caux Christine, Caux Christophe, Gilbert Benoit, Halkic Nermin, La Rosa Stefano, Romero Pedro, Sempoux Christine, de Leval Laurence, 2019/03. 1.
 
Lokal fortgeschrittenes mit neoadjuvanter Radiochemotherapie behandeltes Rektumkarzinom (LFRK): Histopathologische Korrelation von diffusionsgewichteter Magnetresonanztomographie und multiparametrischer PET/CT [Response of locally advanced rectal cancer (LARC) to radiochemotherapy: DW-MRI and multiparametric PET/CT in correlation with histopathology]
Cerny M., Dunet V., Rebecchini C., Hahnloser D., Prior J., Sempoux C., Schmidt S., 2019/02. Nuklearmedizin. Nuclear medicine, 58 (1) pp. 28-38. Peer-reviewed.
 
Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.
Bioulac-Sage P., Sempoux C., Frulio N., Le Bail B., Blanc J.F., Castain C., Laurent C., Trillaud H., Chiche L., Balabaud C., 2019/02. Clinics and research in hepatology and gastroenterology, 43 (1) pp. 12-19. Peer-reviewed.
Histology of portal vascular changes associated with idiopathic non-cirrhotic portal hypertension: nomenclature and definition.
Guido M., Alves VAF, Balabaud C., Bathal P.S., Bioulac-Sage P., Colombari R., Crawford J.M., Dhillon A.P., Ferrell L.D., Gill R.M. et al., 2019/01. Histopathology, 74 (2) pp. 219-226. Peer-reviewed.
OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.
Sciarra A., Schmidt S., Pellegrinelli A., Maggioni M., Dondossola D., Pasquier J., Cigala C., Tosi D., Halkic N., Bulfamante G. et al., 2019/01. Liver international, 39 (1) pp. 158-167. Peer-reviewed.
Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre.
Vieira Barbosa J., Fraga M., Saldarriaga J., Hiroz P., Giostra E., Sempoux C., Ferenci P., Moradpour D., 2018/12/17. Swiss medical weekly, 148 pp. w14699. Peer-reviewed.
Local recurrence rate in patients with colorectal cancer liver metastasis after wedge resection or percutaneous radiofrequency ablation.
Vietti Violi N., Duran R., Demartines N., Sempoux C., Guiu B., Bize P.E., Sala N., Halkic N., Knebel J.F., Denys A., 2018/11. International journal of hyperthermia, 34 (7) pp. 1020-1028. Peer-reviewed.
 
β-Klotho deficiency shifts the gut-liver bile acid axis and induces hepatic alterations in mice.
Somm E., Henry H., Bruce S.J., Bonnet N., Montandon S.A., Niederländer N.J., Messina A., Aeby S., Rosikiewicz M., Fajas L. et al., 2018/11/01. American journal of physiology. Endocrinology and metabolism, 315 (5) pp. E833-E847. Peer-reviewed.
 
Impact of biological agents on the prevalence of chemotherapy associated liver injury (CALI): Multicentric study of patients operated for colorectal liver metastases.
Hubert C., Lucidi V., Weerts J., Dili A., Demetter P., Massart B., Komuta M., Navez J., Reding R., Gigot J.F. et al., 2018/10. European journal of surgical oncology, 44 (10) pp. 1532-1538. Peer-reviewed.
Cholangite biliaire primitive : mise à jour [Primary biliary cholangitis : an update]
Vieira Barbosa J., Vionnet J., Sciarra A., Sempoux C., Aubert V., Moradpour D., Fraga Christinet M., 2018/08/29. Revue medicale suisse, 14 (616) pp. 1489-1494. Peer-reviewed.
 
cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation.
Brunt E., Aishima S., Clavien P.A., Fowler K., Goodman Z., Gores G., Gouw A., Kagen A., Klimstra D., Komuta M. et al., 2018/07. Hepatology, 68 (1) pp. 113-126. Peer-reviewed.
 
Hepatocellular nodules in vascular liver diseases.
Sempoux C., Balabaud C., Paradis V., Bioulac-Sage P., 2018/07. Virchows Archiv, 473 (1) pp. 33-44. Peer-reviewed.
 
Vascular liver lesions: contemporary views on long-recognized entities.
Sempoux C., Bioulac-Sage P., 2018/07. Virchows Archiv, 473 (1) pp. 1-2. Peer-reviewed.
 
Acute-on-chronic liver failure 2018: a need for (urgent) liver biopsy?
van Leeuwen D.J., Alves V., Balabaud C., Bhathal P.S., Bioulac-Sage P., Colombari R., Crawford J.M., Dhillon A.P., Ferrell L., Gill R.M. et al., 2018/06. Expert review of gastroenterology & hepatology, 12 (6) pp. 565-573. Peer-reviewed.
 
Quantification of hepatic perfusion and hepatocyte function with dynamic gadoxetic acid-enhanced MRI in patients with chronic liver disease.
Leporq B., Daire J.L., Pastor C.M., Deltenre P., Sempoux C., Schmidt S., Van Beers B.E., 2018/04/16. Clinical science, 132 (7) pp. 813-824. Peer-reviewed.
 
Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis.
Trépo E., Goossens N., Fujiwara N., Song W.M., Colaprico A., Marot A., Spahr L., Demetter P., Sempoux C., Im G.Y. et al., 2018/03. Gastroenterology, 154 (4) pp. 965-975. Peer-reviewed.
 
Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms.
Schoepfer A.M., Simko A., Bussmann C., Safroneeva E., Zwahlen M., Greuter T., Biedermann L., Vavricka S., Godat S., Reinhard A. et al., 2018/03. The American journal of gastroenterology, 113 (3) pp. 348-357. Peer-reviewed.
 
Heterotopic Gastric Mucosa in a Duplication Cyst of the Common Hepatic Duct Mimicking Cholangiocarcinoma.
Sciarra A., Hessler R., Godat S., Fraga M., Dromain C., Duran R., Halkic N., Sempoux C., 2018/02. International journal of surgical pathology, 26 (1) pp. 84-88. Peer-reviewed.
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
 
A case of unusual histiocytic colitis in a chronic alcoholic obese patient with ankylosing spondylitis.
Guerra Diaz N., Sempoux C., Jouret-Mourin A., de Burbure C., Druez P., 2018. Acta gastro-enterologica Belgica, 81 (2) pp. 327-329. Peer-reviewed.
Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review.
Saglietti C., Sciarra A., Abdelrahman K., Schneider V., Karpate A., Nydegger A., Sempoux C., 2018. Frontiers in pediatrics, 6 p. 123. Peer-reviewed.
Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration.
Ciccarelli O., Colson A., De Saeger C., Reding R., Sempoux C., Leclercq I.A., Stärkel P., 2018. OncoTargets and therapy, 11 pp. 7143-7153. Peer-reviewed.
AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.
Carneiro L., Asrih M., Repond C., Sempoux C., Stehle J.C., Leloup C., Jornayvaz F.R., Pellerin L., 2017/12. Molecular metabolism, 6 (12) pp. 1625-1633. Peer-reviewed.
 
Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.
Saldarriaga J., Bisig B., Couchy G., Castain C., Zucman-Rossi J., Balabaud C., Sempoux C., Bioulac-Sage P., 2017/12. Histopathology, 71 (6) pp. 989-993. Peer-reviewed.
 
Liver and systemic hemodynamics in children with cirrhosis: Impact on the surgical management in pediatric living donor liver transplantation.
de Magnée C., Veyckemans F., Pirotte T., Menten R., Dumitriu D., Clapuyt P., Carbonez K., Barrea C., Sluysmans T., Sempoux C. et al., 2017/11. Liver transplantation, 23 (11) pp. 1440-1450. Peer-reviewed.
 
Are we done with the immunohistochemical classification of hepatocellular adenoma? [1618]
Raymond AA, Le Bail B., Paradis V., Ferrell L., Sciarra A., Yeh MM, Clouston AD, Miller G., Sempoux C., Quaglia A. et al., 2017/10/31., 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting pp. 865A-866A dans Hepatology.
 
Reduced hepatocyte uptake of Gd-EOB-DTPA in chronic liver disease is not related to lowered expression of hepatocyte transporters: a radio-pathologic study [625]
Sciarra A., Schmidt S., Daire JL, Leporq B., Van Beers B., Pastor CM, Sempoux C., 2017/10/31., 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting pp. 340A-341A dans Hepathology.
 
06: Visualization of hepatitis E virus RNA and proteins in the human liver
Lenggenhager D, Gouttenoire J., Malehmir M., Bawohl M., Honcharova -Biletska H., Kreutzer S., Semela D., Neuweiler J., Hürlimann S., Aepli P. et al., 2017/10/20. pp. 571-572 dans Swiss Pathology Days, Der Pathologe.
Sterilization of tumor-positive lymph nodes of esophageal cancer by neo-adjuvant treatment is associated with worse survival compared to tumor-negative lymph nodes treated with surgery first.
Mantziari S., Allemann P., Winiker M., Sempoux C., Demartines N., Schäfer M., 2017/09. Journal of surgical oncology, 116 (4) pp. 524-532. Peer-reviewed.
 
Visualization of hepatitis E virus RNA and proteins in the human liver.
Lenggenhager D., Gouttenoire J., Malehmir M., Bawohl M., Honcharova-Biletska H., Kreutzer S., Semela D., Neuweiler J., Hürlimann S., Aepli P. et al., 2017/09. Journal of hepatology, 67 (3) pp. 471-479. Peer-reviewed.
 
Lésions hépatiques focales bénignes : revue clinique, radiologique et pathologique [Benign focal liver lesions: a clinical, radiological and pathological review]
Abdelrahman K., Schmidt S., Sciarra A., Sempoux C., 2017/08/30. Revue medicale suisse, 13 (572) pp. 1474-1479. Peer-reviewed.
 
Hepatocellular Adenomas: Morphology and Genomics.
Bioulac-Sage P., Sempoux C., Balabaud C., 2017/06. Gastroenterology clinics of North America, 46 (2) pp. 253-272. Peer-reviewed.
 
The caspase-3/p120 RasGAP stress-sensing module reduces liver cancer incidence but does not affect overall survival in gamma-irradiated and carcinogen-treated mice.
Vanli G., Sempoux C., Widmann C., 2017/06. Molecular carcinogenesis, 56 (6) pp. 1680-1684. Peer-reviewed.
 
Toxocarose : une maladie négligée en Suisse ? [Toxocariasis, a neglected disease in Switzerland ?]
Duréault A., Perez Valdes C., Weber L., Ogna A., Sempoux C., Manuel O., Delaloye J., 2017/04/12. Revue medicale suisse, 13 (558) pp. 815-819. Peer-reviewed.
Detection and Viability of Colorectal Liver Metastases After Neoadjuvant Chemotherapy: A Multiparametric PET/CT-MRI Study.
Dunet V., Halkic N., Prior J.O., Anaye A., Meuli R.A., Sempoux C., Denys A., Schmidt S., 2017/04. Clinical nuclear medicine, 42 (4) pp. 258-263. Peer-reviewed.
 
Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.
Sempoux C., Bisig B., Couchy G., Balabaud C., Zucman-Rossi J., Bioulac-Sage P., 2017/04. Human pathology, 62 pp. 122-125. Peer-reviewed.
 
Hepatocellular adenoma: Classification, variants and clinical relevance.
Bioulac-Sage P., Sempoux C., Balabaud C., 2017/03. Seminars in diagnostic pathology, 34 (2) pp. 112-125. Peer-reviewed.
 
Validation of the prognostic value of histologic scoring systems in primary sclerosing cholangitis: An international cohort study.
de Vries E.M., de Krijger M., Färkkilä M., Arola J., Schirmacher P., Gotthardt D., Goeppert B., Trivedi P.J., Hirschfield G.M., Ytting H. et al., 2017/03. Hepatology, 65 (3) pp. 907-919. Peer-reviewed.
 
Variant differentiation patterns in primary liver carcinoma.
Sempoux C., Paradis V., Saxena R., 2017/03. Seminars in diagnostic pathology, 34 (2) pp. 176-182. Peer-reviewed.
Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis.
Bussmann C., Schoepfer A.M., Safroneeva E., Haas N., Godat S., Sempoux C., Simon H.U., Straumann A., 2016/12. Endoscopy, 48 (12) pp. 1069-1075. Peer-reviewed.
 
A436: Glutamine synthetase immunohistochemical staining patterns correlate with molecular abnormalities of b-catenin pathway in hepatocellular adenoma
Calderaro J., Sempoux C., Rebouissou S., Bisig B., Cappellen D., Le Bail B., Zucman-Rossi J., Balabaud C., Bioulac-Sage P., 2016/11/15. pp. 221A-222A dans 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Hepatology.
 
Oral valganciclovir for CMV gastritis.
Saouli A.C., Salvade I., Saldarriaga J., Manuel O., Venetz J.P., Golshayan D., Sempoux C., Pascual M., 2016/09. Clinics and research in hepatology and gastroenterology, 40 (4) pp. e50-1. Peer-reviewed.
 
Gastroentérite à éosinophiles [Eosinophilic gastrointestinal disorders]
Burgmann K., Brunel C., Sempoux C., Ribi C., Godat S., Moradpour D., Schoepfer A.M., 2016/08/31. Revue medicale suisse, 13 (528) pp. 1430-1433. Peer-reviewed.
 
Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential.
Gill R.M., Buelow B., Mather C., Joseph N.M., Alves V., Brunt E.M., Liu T.C., Makhlouf H., Marginean C., Nalbantoglu I. et al., 2016/08. Human pathology, 54 pp. 143-151. Peer-reviewed.
Traitement curatif du cancer de l'oesophage: consensus multidisciplinaire multicentrique [Curative treatment for esophageal cancer: results of a multidisciplinary consensus]
Allemann P., Mantziari S., Wagner D., Digklia A., Ozsahin E., De Bari B., Dorta G., Godat S., Montserrat F., Sempoux C. et al., 2016/06/15. Revue medicale suisse, 12 (523) pp. 1165-1169. Peer-reviewed.
 
Relevance of activated hepatic stellate cells in predicting the development of pediatric liver allograft fibrosis.
Venturi C., Reding R., Quinones J.A., Sokal E., Rahier J., Bueno J., Sempoux C., 2016/06. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 22 (6) pp. 822-829. Peer-reviewed.
 
1638: Different Types Of Glutamine Synthetase Immunostaining in Hepatocellular Adenoma
Bioulac-Sage P., Le Bail B., Castain C., Sempoux C., Balabaud C., 2016. pp. 415A-415A dans 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Modern Pathology. Peer-reviewed.
Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.
Demarez C., Hubert C., Sempoux C., Lemaigre F.P., 2016. PloS one, 11 (6) pp. e0157140. Peer-reviewed.
 
Lymph node ratio and surgical quality are strong prognostic factors of rectal cancer: results from a single referral centre.
Leonard D., Remue C., Abbes Orabi N., van Maanen A., Danse E., Dragean A., Debetancourt D., Humblet Y., Jouret-Mourin A., Maddalena F. et al., 2016. Colorectal Disease, 18 (6) pp. O175-O184. Peer-reviewed.
 
Peritoneal sampling and histological assessment of therapeutic response in peritoneal metastasis: proposal of the Peritoneal Regression Grading Score (PRGS)
Solass W., Sempoux C., Detlefsen Sönke., Carr NJ, Bibeau Fr., 2016/01/01. Pleura and Peritoneum, 1 (2). Peer-reviewed.
 
Regorafenib induced severe toxic hepatitis: characterization and discussion.
Sacré A., Lanthier N., Dano H., Aydin S., Leggenhager D., Weber A., Dekairelle A.F., De Cuyper A., Gala J.L., Humblet Y. et al., 2016. Liver International : Official Journal of the International Association For the Study of the Liver, 36 (11) pp. 1590-1594. Peer-reviewed.
 
Review of the quality of total mesorectal excision does not improve the prediction of outcome.
Demetter P., Jouret-Mourin A., Silversmit G., Vandendael T., Sempoux C., Hoorens A., Nagy N., Cuvelier C., Van Damme N., Penninckx F. et al., 2016. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 18 (9) pp. 883-888. Peer-reviewed.
 
Escalating incidence of eosinophilic esophagitis in Canton of Vaud, Switzerland, 1993-2013: a population-based study.
Giriens B., Yan P., Safroneeva E., Zwahlen M., Reinhard A., Nydegger A., Vavricka S., Sempoux C., Straumann A., Schoepfer A.M., 2015/12. Allergy, 70 (12) pp. 1633-1639. Peer-reviewed.
 
Biphenotypic (hepatobiliary) primary liver carcinomas: the work in progress
Brunt EM, Paradis V., Sempoux Christine., Theise ND, 2015/07. Hepatic Oncology, 2 (3) pp. 255-273. Peer-reviewed.
 
Completeness and registration bias in PROCARE, a Belgian multidisciplinary project on cancer of the rectum with participation on a voluntary basis.
Jegou D., Penninckx F., Vandendael T., Bertrand C., Van Eycken E., PROCARE , 2015. European Journal of Cancer (oxford, England : 1990), 51 (9) pp. 1099-1108. Peer-reviewed.
 
Cytological diagnosis of pancreatic neuroendocrine neoplasms
Bongiovanni M., Sempoux C., Nobile A., 2015. pp. 43-50 dans La Rosa S., Sessa F. (eds.) Pancreatic neuroendocrine neoplasms chap. 5, Springer.
 
Extensive profiling of the expression of the indoleamine 2,3-dioxygenase 1 protein in normal and tumoral human tissues.
Théate I., van Baren N., Pilotte L., Moulin P., Larrieu P., Renauld J.C., Hervé C., Gutierrez-Roelens I., Marbaix E., Sempoux C. et al., 2015. Cancer Immunology Research, 3 (2) pp. 161-172. Peer-reviewed.
 
Hepatocellular adenoma management: Call for shared guidelines and multidisciplinary approach.
Blanc J.F., Frulio N., Chiche L., Sempoux C., Annet L., Hubert C., Gouw A.S., de Jong K.P., Bioulac-Sage P., Balabaud C., 2015. Clinics and Research In Hepatology and Gastroenterology, 39 (2) pp. 180-187.
 
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Mu X., Español-Suñer R., Mederacke I., Affò S., Manco R., Sempoux C., Lemaigre F.P., Adili A., Yuan D., Weber A. et al., 2015. Journal of Clinical Investigation, 125 (10) pp. 3891-3903. Peer-reviewed.
 
Hepatocellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders.
Sempoux C., Paradis V., Komuta M., Wee A., Calderaro J., Balabaud C., Quaglia A., Bioulac-Sage P., 2015. Journal of Hepatology, 63 (5) pp. 1173-1180. Peer-reviewed.
 
Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro.
Henquin J.C., Nenquin M., Guiot Y., Rahier J., Sempoux C., 2015. Diabetes, 64 (10) pp. 3543-3553. Peer-reviewed.
 
Impact of Intraoperative Pancreatoscopy with Intraductal Biopsies on Surgical Management of Intraductal Papillary Mucinous Neoplasm of the Pancreas.
Navez J., Hubert C., Gigot J.F., Borbath I., Annet L., Sempoux C., Lannoy V., Deprez P., Jabbour N., 2015. Journal of the American College of Surgeons, 221 (5) pp. 982-987. Peer-reviewed.
 
Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain.
Gurevich M., Guy-Viterbo V., Janssen M., Stephenne X., Smets F., Sokal E., Lefebvre C., Balligand J.L., Pirotte T., Veyckemans F. et al., 2015. Annals of Surgery, 262 (6) pp. 1141-1149. Peer-reviewed.
 
Occult HBV reactivation induced by ibrutinib treatment: a case report.
de Jésus Ngoma P., Kabamba B., Dahlqvist G., Sempoux C., Lanthier N., Shindano T., Van Den Neste E., Horsmans Y., 2015. Acta Gastro-enterologica Belgica, 78 (4) pp. 424-426. Peer-reviewed.
 
Panitumumab as a radiosensitizing agent in KRAS wild-type locally advanced rectal cancer.
Mardjuadi F.I., Carrasco J., Coche J.C., Sempoux C., Jouret-Mourin A., Scalliet P., Goeminne J.C., Daisne J.F., Delaunoit T., Vuylsteke P. et al., 2015. Targeted Oncology, 10 (3) pp. 375-383. Peer-reviewed.
 
Pathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone.
Carrasco J., Gizzi M., Pairet G., Lannoy V., Lefesvre P., Gigot J.F., Hubert C., Jouret-Mourin A., Humblet Y., Canon J.L. et al., 2015. British Journal of Cancer, 113 (9) pp. 1298-1304. Peer-reviewed.
 
Quantitative contribution of prognosticators to oncologic outcome after rectal cancer resection.
Leonard D., Penninckx F., Laenen A., Kartheuser A., PROCARE , 2015. Diseases of the Colon and Rectum, 58 (6) pp. 566-574. Peer-reviewed.
 
Scoring the quality of total mesorectal excision for the prediction of cancer-specific outcome.
Leonard D., Penninckx F., Laenen A., Kartheuser A., PROCARE , 2015. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 17 (5) pp. O115-O122. Peer-reviewed.
 
Solitary extramedullary plasmocytoma of the thyroid: a case report and histological approach to plasma cells infiltrate in the thyroid gland.
Wilmars M.M., Knoops L., Sempoux C., Galant C., Geets X., Poirel H.A., Ameye G., Camboni A., 2015. Acta Clinica Belgica, 70 (2) pp. 133-137. Peer-reviewed.
 
SOX9 regulates ERBB signalling in pancreatic cancer development.
Grimont A., Pinho A.V., Cowley M.J., Augereau C., Mawson A., Giry-Laterrière M., Van den Steen G., Waddell N., Pajic M., Sempoux C. et al., 2015. Gut, 64 (11) pp. 1790-1799. Peer-reviewed.
 
Well-differentiated hepatocellular neoplasm of uncertain malignant potential.
Balabaud C., Bioulac-Sage P., Ferrell L., Kakar S., Paradis V., Quaglia A., Sempoux C., Thung S., Zucman-Rossi J., 2015. Human Pathology, 46 (4) pp. 634-635. Peer-reviewed.
 
Coexistence of inflammatory hepatocellular adenomas with HNF1α-inactivated adenomas: is there an association?
Castain C., Sempoux C., Brunt E.M., Causse O., Heitzmann A., Hernandez-Prera J.C., Le Bail B., Schirmacher P., Thung S.N., Balabaud C. et al., 2014. Histopathology, 64 (6) pp. 890-895. Peer-reviewed.
 
Dynamics of allograft fibrosis in pediatric liver transplantation.
Venturi C., Sempoux C., Quinones J.A., Bourdeaux C., Hoyos S.P., Sokal E., Reding R., 2014. American Journal of Transplantation, 14 (7) pp. 1648-1656. Peer-reviewed.
 
Effect of hospital volume on quality of care and outcome after rectal cancer surgery.
Leonard D., Penninckx F., Kartheuser A., Laenen A., Van Eycken E., PROCARE , 2014. British Journal of Surgery, 101 (11) pp. 1475-1482.
 
Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz mice.
Legry V., Van Rooyen D.M., Lambert B., Sempoux C., Poekes L., Español-Suñer R., Molendi-Coste O., Horsmans Y., Farrell G.C., Leclercq I.A., 2014. Clinical Science, 127 (7) pp. 507-518. Peer-reviewed.
 
Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.
Zhu A.X., Borger D.R., Kim Y., Cosgrove D., Ejaz A., Alexandrescu S., Groeschl R.T., Deshpande V., Lindberg J.M., Ferrone C. et al., 2014. Annals of Surgical Oncology, 21 (12) pp. 3827-3834. Peer-reviewed.
 
Immunohistochemical pitfalls in the diagnosis of focal nodular hyperplasia and inflammatory hepatocellular adenoma.
Bioulac-Sage P., Sempoux C., Balabaud C., 2014. Clinics and Research In Hepatology and Gastroenterology, 38 (3) pp. 245-249. Peer-reviewed.
 
Intraductal biliary polypectomy performed with a nasogastroscope.
Druez A., Kim E., Sempoux C., Deprez P., 2014. Endoscopy International Open, 2 (2) pp. E124-E125. Peer-reviewed.
 
Is 18F-flutemetamol PET/CT able to reveal cardiac amyloidosis?
Lhommel R., Sempoux C., Ivanoiu A., Michaux L., Gerber B., 2014. Clinical Nuclear Medicine, 39 (8) pp. 747-749. Peer-reviewed.
 
Is minimal, [almost] steroid-free immunosuppression a safe approach in adult liver transplantation? Long-term outcome of a prospective, double blind, placebo-controlled, randomized, investigator-driven study.
Lerut J.P., Pinheiro R.S., Lai Q., Stouffs V., Orlando G., Juri J.M., Ciccarelli O., Sempoux C., Roggen F.M., De Reyck C. et al., 2014. Annals of Surgery, 260 (5) pp. 886-91; discussion 891-2. Peer-reviewed.
 
Mesenteric inflammatory myofibroblastic tumor: MRI and CT imaging correlated to anatomical pathology.
Kirchgesner T., Danse E., Sempoux C., Annet L., Dragean C., Trefois P., Abbes Orabi N., Kartheuser A., 2014. Jbr-btr : Organe De La Societe Royale Belge De Radiologie (srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (kbvr), 97 (5) pp. 301-302. Peer-reviewed.
 
Pancreatic neuroendocrine tumour grading on endoscopic ultrasound-guided fine needle aspiration: high reproducibility and inter-observer agreement of the Ki-67 labelling index.
Weynand B., Borbath I., Bernard V., Sempoux C., Gigot J.F., Hubert C., Lannoy V., Deprez P.H., Jouret-Mourin A., 2014. Cytopathology, 25 (6) pp. 389-395. Peer-reviewed.
 
Pictures of focal nodular hyperplasia and hepatocellular adenomas.
Sempoux C., Balabaud C., Bioulac-Sage P., 2014. World Journal of Hepatology, 6 (8) pp. 580-595. Peer-reviewed.
 
Regulation of hepatic EAAT-2 glutamate transporter expression in human liver cholestasis.
Najimi M., Stéphenne X., Sempoux C., Sokal E., 2014. World Journal of Gastroenterology, 20 (6) pp. 1554-1564. Peer-reviewed.
 
Benign hepatocellular nodules: what have we learned using the patho-molecular classification.
Sempoux C., Chang C., Gouw A., Chiche L., Zucman-Rossi J., Balabaud C., Bioulac-Sage P., 2013. Clinics and Research in Hepatology and Gastroenterology, 37 (4) pp. 322-327. Peer-reviewed.
 
Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.
Nollevaux M.C., Rahier J., Marchandise J., Thurion P., Godecharles S., Van den Steen G., Jamart J., Sempoux C., Jacquemin P., Guiot Y., 2013. American Journal of Physiology. Endocrinology and Metabolism, 304 (7) pp. E711-E723.
 
Combination of gemcitabine and cetuximab in patients with advanced cholangiocarcinoma: a phase II study of the Belgian Group of Digestive Oncology.
Borbath I., Ceratti A., Verslype C., Demols A., Delaunoit T., Laurent S., Deleporte A., Vergauwe P., Van Maanen A., Sempoux C. et al., 2013. Annals of Oncology, 24 (11) pp. 2824-2829.
 
Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells.
Henquin J.C., Sempoux C., Marchandise J., Godecharles S., Guiot Y., Nenquin M., Rahier J., 2013. Diabetes, 62 (5) pp. 1689-1696.
 
Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification.
Balabaud C., Al-Rabih W.R., Chen P.J., Evason K., Ferrell L., Hernandez-Prera J.C., Huang S.F., Longerich T., Park Y.N., Quaglia A. et al., 2013. International Journal of Hepatology, 2013 p. 268625.
 
Histological and immunohistochemical revision of hepatocellular adenomas: a learning experience.
Fonseca S., Hoton D., Dardenne S., Annet L., Hubert C., Godecharles S., Jouret-Mourin A., Reding R., Otte J.B., Rahier J. et al., 2013. International Journal of Hepatology, 2013 p. 398308. Peer-reviewed.
 
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.
Lebrun V., Molendi-Coste O., Lanthier N., Sempoux C., Cani P.D., van Rooijen N., Stärkel P., Horsmans Y., Leclercq I.A., 2013. Clinical Science, 125 (11) pp. 501-511.
 
Need for objective and reproducible criteria in histopathological assessment of total mesorectal excision specimens: lessons from a national improvement project.
Demetter P., Vandendael T., Sempoux C., Ectors N., Cuvelier C.A., Nagy N., Hoorens A., Jouret-Mourin A., PROCARE , 2013. Colorectal Disease, 15 (11) pp. 1351-1358.
 
Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context.
Bioulac-Sage P., Sempoux C., Possenti L., Frulio N., Laumonier H., Laurent C., Chiche L., Frédéric Blanc J., Saric J., Trillaud H. et al., 2013. International Journal of Hepatology, 2013 p. 253261.
 
Prevalence of nonalcoholic steatohepatitis among patients with resectable intrahepatic cholangiocarcinoma.
Reddy S.K., Hyder O., Marsh J.W., Sotiropoulos G.C., Paul A., Alexandrescu S., Marques H., Pulitano C., Barroso E., Aldrighetti L. et al., 2013. Journal of Gastrointestinal Surgery, 17 (4) pp. 748-755.
 
Risk adjusted benchmarking of abdominoperineal excision for rectal adenocarcinoma in the context of the Belgian PROCARE improvement project.
Penninckx F., Fieuws S., Beirens K., Demetter P., Ceelen W., Kartheuser A., Molle G., Van de Stadt J., Vindevoghel K., Van Eycken E. et al., 2013. Gut, 62 (7) pp. 1005-1011. Peer-reviewed.
 
Sinusoidal obstruction syndrome (SOS) related to chemotherapy for colorectal liver metastases: factors predictive of severe SOS lesions and protective effect of bevacizumab.
Hubert C., Sempoux C., Humblet Y., van den Eynde M., Zech F., Leclercq I., Gigot J.F., 2013. HPB, 15 (11) pp. 858-864.
 
Commentary: "Cirrhosis or not cirrhosis": should we discontinue the term?
Sempoux C., Rahier J., 2012. Clinics and Research In Hepatology and Gastroenterology, 36 (5) pp. 405-407. Peer-reviewed.
 
Defunctioning stoma and anastomotic leak rate after total mesorectal excision with coloanal anastomosis in the context of PROCARE.
Beirens K., Penninckx F., PROCARE , 2012. Acta Chirurgica Belgica, 112 (1) pp. 10-14. Peer-reviewed.
 
Exploring limits for data registration in the context of PROCARE, a quality improvement project on rectal cancer.
Vandendael T., Penninckx F., Bertrand C., Ceelen W., Danse E., Demetter P., Haustermans K., Laurent S., Molle G., Vandestadt J. et al., 2012. Acta Chirurgica Belgica, 112 (1) pp. 15-23. Peer-reviewed.
 
From interventional radiology to laparoscopic liver resection as complementary strategies in the treatment of hepatic abscess caused by ingested foreign bodies.
Riani E.B., Tancredi I., Sempoux C., Hubert C., Goffette P., Gigots J.F., 2012. Hepato-gastroenterology, 59 (114) pp. 558-560.
 
Human equilibrative nucleoside transporter 1 (hENT1) expression is a potential predictive tool for response to gemcitabine in patients with advanced cholangiocarcinoma.
Borbath I., Verbrugghe L., Lai R., Gigot J.F., Humblet Y., Piessevaux H., Sempoux C., 2012. European Journal of Cancer, 48 (7) pp. 990-996. Peer-reviewed.
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