Ping-Chih Ho

Publications | Mémoires et thèses

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105 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2012 | 2011 | 2009 | 2008 |
2024
TAM-tastic: from resistance to resilience in cancer.
Low J.T., Ho P.C., Matsushita M., 2024/11. Trends in pharmacological sciences, 45 (11) pp. 953-954. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_55DD4DDBA3E0]
 
A pinch of salt boosts T cell function.
Hajdu K.L., Rousseau L., Ho P.C., 2024/10. Nature immunology, 25 (10) pp. 1772-1774. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_686BF083E201]
 
PPARβ/δ-orchestrated metabolic reprogramming supports the formation and maintenance of memory CD8+ T cells.
Bevilacqua A., Franco F., Lu Y.T., Rahiman N., Kao K.C., Chuang Y.M., Zhu Y., Held W., Xie X., Gunsalus K.C. et al., 2024/08/23. Science immunology, 9 (98) pp. eadn2717. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EBC9ACE2A41D]
PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells.
Morotti M., Grimm A.J., Hope H.C., Arnaud M., Desbuisson M., Rayroux N., Barras D., Masid M., Murgues B., Chap B.S. et al., 2024/05. Nature, 629 (8011) pp. 426-434. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5FCB44D6E4AA]
 
Metabolic interplay: tumor macrophages and regulatory T cells.
Vilbois S., Xu Y., Ho P.C., 2024/03. Trends in cancer, 10 (3) pp. 242-255. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0E0F7603EBDF]
Immunosurveillance encounters cancer metabolism.
Chuang Y.M., Tzeng S.F., Ho P.C., Tsai C.H., 2024/02. EMBO reports, 25 (2) pp. 471-488. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A1C1A9A9C8FE]
2023
 
Re-"Formate" T-cell Antitumor Responses.
Lin M.C., Moller S.H., Ho P.C., 2023/12/12. Cancer discovery, 13 (12) pp. 2507-2509. Peer-reviewed.
[DOI][Pmid][serval:BIB_312479403733]
 
About the Rising Star.
Ho Ping-Chih, 2023/10/04. Cancer immunology research, 11 (10) p. 1302. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_29D688A5F0A8]
 
Mitochondria Dictate Function and Fate of HSCs and T Cells.
Xu Y., Chiang Y.H., Ho P.C., Vannini N., 2023/10/04. Cancer immunology research, 11 (10) pp. 1303-1313. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0B5C977CFB5B]
 
Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8<sup>+</sup> T cell formation.
Franco F., Bevilacqua A., Wu R.M., Kao K.C., Lin C.P., Rousseau L., Peng F.T., Chuang Y.M., Peng J.J., Park J. et al., 2023/09/29. Science immunology, 8 (87) pp. eadf7579. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_22AAC08FD04B]
Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming.
Zeng W., Li F., Jin S., Ho P.C., Liu P.S., Xie X., 2023/09/23. Journal of experimental & clinical cancer research, 42 (1) p. 245. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_620795DC3E45]
Author Correction: CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions.
Liu P.S., Chen Y.T., Li X., Hsueh P.C., Tzeng S.F., Chen H., Shi P.Z., Xie X., Parik S., Planque M. et al., 2023/09. Nature immunology, 24 (9) p. 1591. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_01B6D00F5286]
 
cDC1 craves glutamine for its glory.
Vilbois S., Park J., Ho P.C., 2023/09. Nature immunology, 24 (9) pp. 1405-1406. Peer-reviewed.
[DOI][Pmid][serval:BIB_EA0B54BB2ABB]
 
Control of immune cell function by the unfolded protein response.
Di Conza G., Ho P.C., Cubillos-Ruiz J.R., Huang S.C., 2023/09. Nature reviews. Immunology, 23 (9) pp. 546-562. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_84EB04B67D6F]
Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems.
Girotra M., Chiang Y.H., Charmoy M., Ginefra P., Hope H.C., Bataclan C., Yu Y.R., Schyrr F., Franco F., Geiger H. et al., 2023/09. Nature aging, 3 (9) pp. 1057-1066. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E2F47D89B9B9]
 
Reductive carboxylation epigenetically instructs T cell differentiation.
Jaccard A., Wyss T., Maldonado-Pérez N., Rath J.A., Bevilacqua A., Peng J.J., Lepez A., Von Gunten C., Franco F., Kao K.C. et al., 2023/09. Nature, 621 (7980) pp. 849-856. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D1AE6E79E2FB]
A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8<sup>+</sup> T cells.
Chang Y.W., Hsiao H.W., Chen J.P., Tzeng S.F., Tsai C.H., Wu C.Y., Hsieh H.H., Carmona S.J., Andreatta M., Di Conza G. et al., 2023/08/15. Cell reports. Medicine, 4 (8) p. 101154. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_21D296C123A7]
 
The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages.
Dang B., Gao Q., Zhang L., Zhang J., Cai H., Zhu Y., Zhong Q., Liu J., Niu Y., Mao K. et al., 2023/05/30. Cell reports, 42 (5) p. 112471. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2E097BAB796F]
 
Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report.
Cable J., Rathmell J.C., Pearce E.L., Ho P.C., Haigis M.C., Mamedov M.R., Wu M.J., Kaech S.M., Lynch L., Febbraio M.A. et al., 2023/05. Annals of the New York Academy of Sciences, 1523 (1) pp. 38-50. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_545ECF7E63DA]
 
Metabolic challenges and interventions in CAR T cell therapy.
Peng J.J., Wang L., Li Z., Ku C.L., Ho P.C., 2023/04/14. Science immunology, 8 (82) pp. eabq3016. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AC84BA282FC0]
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions.
Liu P.S., Chen Y.T., Li X., Hsueh P.C., Tzeng S.F., Chen H., Shi P.Z., Xie X., Parik S., Planque M. et al., 2023/03. Nature immunology, 24 (3) pp. 452-462. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E5287AECF4CC]
 
Microenvironment-driven metabolic adaptations guiding CD8<sup>+</sup> T cell anti-tumor immunity.
Park J., Hsueh P.C., Li Z., Ho P.C., 2023/01/10. Immunity, 56 (1) pp. 32-42. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E95E539D455E]
 
Immunoediting instructs tumor metabolic reprogramming to support immune evasion.
Tsai C.H., Chuang Y.M., Li X., Yu Y.R., Tzeng S.F., Teoh S.T., Lindblad K.E., Di Matteo M., Cheng W.C., Hsueh P.C. et al., 2023/01/03. Cell metabolism, 35 (1) pp. 118-133.e7. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E4E3E6C91256]
2022
CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation.
Fernández-García J., Franco F., Parik S., Altea-Manzano P., Pane A.A., Broekaert D., van Elsen J., Vermeire I., Schalley T., Planque M. et al., 2022/11/15. Cell reports, 41 (7) p. 111639. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_DCE101C7865A]
 
Metabolic communication in the tumour-immune microenvironment.
Kao K.C., Vilbois S., Tsai C.H., Ho P.C., 2022/11. Nature cell biology, 24 (11) pp. 1574-1583. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EA98D2D63E56]
Metabolic guidance and stress in tumors modulate antigen-presenting cells.
Park J., Wang L., Ho P.C., 2022/10/16. Oncogenesis, 11 (1) p. 62. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6BDDFB239E9D]
 
IFNα Potentiates Immune-Checkpoint Blockade by Rewiring Metabolic Cross-talk.
Kao K.C., Jaccard A., Ho P.C., 2022/07/06. Cancer discovery, 12 (7) pp. 1615-1616. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_255996E55B3C]
 
Androgen effects cause sex-biased impairment of CD8<sup>+</sup> T cell antitumor activity.
Bevilacqua A., Ho P.C., 2022/07. Science immunology, 7 (73) pp. eabq6783. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F61374C6BB9B]
Lipid-loaded macrophages as new therapeutic target in cancer.
Marelli G., Morina N., Portale F., Pandini M., Iovino M., Di Conza G., Ho P.C., Di Mitri D., 2022/07. Journal for immunotherapy of cancer, 10 (7) pp. e004584. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FD2BFB720D7B]
The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
Wenes M., Jaccard A., Wyss T., Maldonado-Pérez N., Teoh S.T., Lepez A., Renaud F., Franco F., Waridel P., Yacoub Maroun C. et al., 2022/05/03. Cell metabolism, 34 (5) pp. 731-746.e9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17EB92736564]
Metabolic dynamics instruct CD8<sup>+</sup> T-cell differentiation and functions.
Bevilacqua A., Li Z., Ho P.C., 2022/04. European journal of immunology, 52 (4) pp. 541-549. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B5AE6597A0A]
Metabolic programming in dendritic cells tailors immune responses and homeostasis.
Møller S.H., Wang L., Ho P.C., 2022/03. Cellular & molecular immunology, 19 (3) pp. 370-383. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_28FD58401C9C]
 
Metabolic programs tailor T cell immunity in viral infection, cancer, and aging.
Møller S.H., Hsueh P.C., Yu Y.R., Zhang L., Ho P.C., 2022/03/01. Cell metabolism, 34 (3) pp. 378-395. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3C4C3CF20FD3]
 
PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Raines L.N., Zhao H., Wang Y., Chen H.Y., Gallart-Ayala H., Hsueh P.C., Cao W., Koh Y., Alamonte-Loya A., Liu P.S. et al., 2022/03. Nature immunology, 23 (3) pp. 431-445. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8642BC35A947]
2021
 
Challenges and opportunities in 2021.
Akkari L., Finley S.D., Ho P.C., Jenkins M., Maier B.B., McGranahan N., Mutebi M., Perera R.M., Robles-Espinoza C.D., Vardhana S. et al., 2021/12. Nature cancer, 2 (12) pp. 1278-1283. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88181154656E]
 
Fueling T-cell Antitumor Immunity: Amino Acid Metabolism Revisited.
Han C., Ge M., Ho P.C., Zhang L., 2021/12. Cancer immunology research, 9 (12) pp. 1373-1382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A31A9CC09CD4]
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G., Tsai C.H., Gallart-Ayala H., Yu Y.R., Franco F., Zaffalon L., Xie X., Li X., Xiao Z., Raines L.N. et al., 2021/11. Nature immunology, 22 (11) pp. 1403-1415. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_38FF542D6B24]
 
Glutamine gluttony of efferocytes.
Jaccard A., Li X., Ho P.C., 2021/10. Nature metabolism, 3 (10) pp. 1280-1281. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0E25E488861C]
DCision-making in tumors governs T cell anti-tumor immunity.
Alfei F., Ho P.C., Lo W.L., 2021/08. Oncogene, 40 (34) pp. 5253-5261. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A205E6D27239]
 
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8<sup>+</sup> T cells in tumors.
Xu S., Chaudhary O., Rodríguez-Morales P., Sun X., Chen D., Zappasodi R., Xu Z., Pinto AFM, Williams A., Schulze I. et al., 2021/07/13. Immunity, 54 (7) pp. 1561-1577.e7. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7490E53D6718]
Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.
Dumauthioz N., Tschumi B., Wenes M., Marti B., Wang H., Franco F., Li W., Lopez-Mejia I.C., Fajas L., Ho P.C. et al., 2021/07. Cellular & molecular immunology, 18 (7) pp. 1761-1771. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D554C59D6F3C]
 
Can tumor cells take it all away?
Kohl A., Kao K.C., Ho P.C., 2021/06/01. Cell metabolism, 33 (6) pp. 1071-1072. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C38ABD4E6369]
Metabolic reprogramming of terminally exhausted CD8<sup>+</sup> T cells by IL-10 enhances anti-tumor immunity.
Guo Y., Xie Y.Q., Gao M., Zhao Y., Franco F., Wenes M., Siddiqui I., Bevilacqua A., Wang H., Yang H. et al., 2021/06. Nature immunology, 22 (6) pp. 746-756. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C5D0B4808515]
Rapid Noninvasive Skin Monitoring by Surface Mass Recording and Data Learning.
Zhu Y., Lesch A., Li X., Lin T.E., Gasilova N., Jović M., Pick H.M., Ho P.C., Girault H.H., 2021/05/24. JACS Au, 1 (5) pp. 598-611. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2FC489BC0711]
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Ercolano G., Gomez-Cadena A., Dumauthioz N., Vanoni G., Kreutzfeldt M., Wyss T., Michalik L., Loyon R., Ianaro A., Ho P.C. et al., 2021/05/05. Nature communications, 12 (1) p. 2538. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_976017D4D887]
 
Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer.
Xin G., Chen Y., Topchyan P., Kasmani M.Y., Burns R., Volberding P.J., Wu X., Cohn A., Chen Y., Lin C.W. et al., 2021/04. Cancer immunology research, 9 (4) pp. 454-469. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2606CDB8F028]
CTLA-4 blockade drives loss of T<sub>reg</sub> stability in glycolysis-low tumours.
Zappasodi R., Serganova I., Cohen I.J., Maeda M., Shindo M., Senbabaoglu Y., Watson M.J., Leftin A., Maniyar R., Verma S. et al., 2021/03. Nature, 591 (7851) pp. 652-658. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_73853A7202A4]
 
Lactate modulation of immune responses in inflammatory versus tumour microenvironments.
Certo M., Tsai C.H., Pucino V., Ho P.C., Mauro C., 2021/03. Nature reviews. Immunology, 21 (3) pp. 151-161. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EEC32C274BAF]
Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis.
Ma M., Ghosh S., Tavernari D., Katarkar A., Clocchiatti A., Mazzeo L., Samarkina A., Epiney J., Yu Y.R., Ho P.C. et al., 2021/02/01. The Journal of experimental medicine, 218 (2) pp. e20201137. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3B2A745CA757]
2020
Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Shang M., Cappellesso F., Amorim R., Serneels J., Virga F., Eelen G., Carobbio S., Rincon M.Y., Maechler P., De Bock K. et al., 2020/11. Nature, 587 (7835) pp. 626-631. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3434B6E6C298]
 
Metabolic and epigenetic regulation of T-cell exhaustion.
Franco F., Jaccard A., Romero P., Yu Y.R., Ho P.C., 2020/10. Nature metabolism, 2 (10) pp. 1001-1012. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C6CC159592FD]
 
The hidden side of PD-L1.
Jaccard A., Ho P.C., 2020/09. Nature cell biology, 22 (9) pp. 1031-1032. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CDDD22AA09ED]
A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts.
Krasny L., Bland P., Burns J., Lima N.C., Harrison P.T., Pacini L., Elms M.L., Ning J., Martinez V.G., Yu Y.R. et al., 2020/07/14. Disease models & mechanisms, 13 (7) pp. dmm044586. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AECF31D38959]
Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4<sup>+</sup> T cells.
Rath J.A., Bajwa G., Carreres B., Hoyer E., Gruber I., Martínez-Paniagua M.A., Yu Y.R., Nouraee N., Sadeghi F., Wu M. et al., 2020/07. Science advances, 6 (27) pp. eaaz7809. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D26F38B87AE4]
 
Metabolic adaptation orchestrates tissue context-dependent behavior in regulatory T cells.
Wang H., Lu C.H., Ho P.C., 2020/05. Immunological reviews, 295 (1) pp. 126-139. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_06F683976602]
miR-155 Overexpression in OT-1 CD8<sup>+</sup> T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen.
Monnot G.C., Martinez-Usatorre A., Lanitis E., Lopes S.F., Cheng W.C., Ho P.C., Irving M., Coukos G., Donda A., Romero P., 2020/03/27. Molecular therapy oncolytics, 16 pp. 111-123. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_39DC24C5C585]
ER Stress Responses: An Emerging Modulator for Innate Immunity.
Di Conza G., Ho P.C., 2020/03/12. Cells, 9 (3) p. 695. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A1E25DB37FD0]
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Wang H., Franco F., Tsui Y.C., Xie X., Trefny M.P., Zappasodi R., Mohmood S.R., Fernández-García J., Tsai C.H., Schulze I. et al., 2020/03. Nature immunology, 21 (3) pp. 298-308. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B4EB98E7D705]
 
Immunity, Hypoxia, and Metabolism-the Ménage à Trois of Cancer: Implications for Immunotherapy.
Riera-Domingo C., Audigé A., Granja S., Cheng W.C., Ho P.C., Baltazar F., Stockmann C., Mazzone M., 2020/01/01. Physiological reviews, 100 (1) pp. 1-102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6448AD630AF8]
2019
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.
Salomé B., Gomez-Cadena A., Loyon R., Suffiotti M., Salvestrini V., Wyss T., Vanoni G., Ruan D.F., Rossi M., Tozzo A. et al., 2019/11/26. Blood advances, 3 (22) pp. 3674-3687. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BC26C680B22]
 
Tape-Stripping Electrochemical Detection of Melanoma.
Darvishi S., Pick H., Lin T.E., Zhu Y., Li X., Ho P.C., Girault H.H., Lesch A., 2019/10/15. Analytical chemistry, 91 (20) pp. 12900-12908. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4B5AE89097F4]
 
Fifty Shades of α-Ketoglutarate on Cellular Programming.
Di Conza G., Tsai C.H., Ho P.C., 2019/10/03. Molecular cell, 76 (1) pp. 1-3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CB375784E0F9]
 
Firing Up Cold Tumors.
Cheng W.C., Ho P.C., 2019/09. Trends in cancer, 5 (9) pp. 528-530. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F50ED56DE9EB]
 
Sculpting tumor microenvironment with immune system: from immunometabolism to immunoediting.
Yu Y.R., Ho P.C., 2019/08. Clinical and experimental immunology, 197 (2) pp. 153-160. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F2A32ECC9A7]
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.
Ayeni D., Miller B., Kuhlmann A., Ho P.C., Robles-Oteiza C., Gaefele M., Levy S., de Miguel F.J., Perry C., Guan T. et al., 2019/07/10. Journal for immunotherapy of cancer, 7 (1) p. 172. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_765E95D84B97]
 
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy.
Li X., Wenes M., Romero P., Huang S.C., Fendt S.M., Ho P.C., 2019/07. Nature reviews. Clinical oncology, 16 (7) pp. 425-441. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F7C5AE601718]
 
MALDI Detection of Exosomes: A Potential Tool for Cancer Studies
Zhu Yingdi, Pick Horst, Gasilova Natalia, Li Xiaoyun, Lin Tzu-En, Laeubli Heinz Philipp, Zippelius Alfred, Ho Ping-Chih, Girault Hubert H., 2019/05. Chem, 5 (5) pp. 1318-1336.
[DOI][WoS][serval:BIB_05812E4472A3]
 
Publisher Correction: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/04..
[DOI][WoS][Pmid][serval:BIB_2453C5C48240]
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret C., Miah SMS, Rota G., Fonta N.P., Wang H., Held W., Birchmeier W., Sexl V., Yang W., Vivier E. et al., 2019/03/29. Nature communications, 10 (1) p. 1444. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1D70F1981844]
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Vannini N., Campos V., Girotra M., Trachsel V., Rojas-Sutterlin S., Tratwal J., Ragusa S., Stefanidis E., Ryu D., Rainer P.Y. et al., 2019/03/07. Cell stem cell, 24 (3) pp. 405-418.e7. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9C9755E6E69D]
 
Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/02. Nature immunology, 20 (2) pp. 206-217. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A10BFBC01F0D]
 
Determining Macrophage Polarization upon Metabolic Perturbation
Liu Pu-Ste, Ho Ping-Chih, 2019. pp. 173-186 dans Metabolic Signaling, Springer New York.
[DOI][WoS][Pmid][serval:BIB_5B2518331659]
2018
 
Sparks Fly in PGE2-Modulated Macrophage Polarization.
Franco F., Wenes M., Ho P.C., 2018/12/18. Immunity, 49 (6) pp. 987-989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_843A58D94237]
Immunometabolism in cancer at a glance.
Singer K., Cheng W.C., Kreutz M., Ho P.C., Siska P.J., 2018/08/02. Disease models & mechanisms, 11 (8) pp. -. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4132BB530AE6]
 
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Castro W., Chelbi S.T., Niogret C., Ramon-Barros C., Welten SPM, Osterheld K., Wang H., Rota G., Morgado L., Vivier E. et al., 2018/08. Nature immunology, 19 (8) pp. 809-820. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A76D5C40117C]
A transcriptionally and functionally distinct PD-1<sup>+</sup> CD8<sup>+</sup> T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.
Thommen D.S., Koelzer V.H., Herzig P., Roller A., Trefny M., Dimeloe S., Kiialainen A., Hanhart J., Schill C., Hess C. et al., 2018/07. Nature medicine, 24 (7) pp. 994-1004. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D581A7793334]
 
Mitochondria: A master regulator in macrophage and T cell immunity.
Liu P.S., Ho P.C., 2018/07. Mitochondrion, 41 pp. 45-50. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F5461A5E94DF]
 
Metabolic adaptation of macrophages in chronic diseases.
Di Conza G., Ho P.C., 2018/02/01. Cancer letters, 414 pp. 250-256. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_886BEAF4AAA4]
2017
 
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Liu P.S., Wang H., Li X., Chao T., Teav T., Christen S., Di Conza G., Cheng W.C., Chou C.H., Vavakova M. et al., 2017/09. Nature immunology, 18 (9) pp. 985-994. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CA3F4F3BEF1D]
 
Metabolic Regulation of Tregs in Cancer: Opportunities for Immunotherapy.
Wang H., Franco F., Ho P.C., 2017/08. Trends in cancer, 3 (8) pp. 583-592. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_49A26876BD66]
 
Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries.
Ho P.C., Kaech S.M., 2017/06. Current opinion in immunology, 46 pp. 38-44. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38C4B8D3BCD4]
Editorial: Immunometabolic Regulations in Adaptive and Innate Immune Cells Shapes and Re-Directs Host Immunity.
Ho P.C., Hess C., 2017. Frontiers in immunology, 8 p. 852. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED9C27EAFE82]
Mitochondrial Control and Guidance of Cellular Activities of T Cells.
Chao T., Wang H., Ho P.C., 2017. Frontiers in immunology, 8 p. 473. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_16BAFFED261C]
2016
Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.
Coutaz M., Hurrell B.P., Auderset F., Wang H., Siegert S., Eberl G., Ho P.C., Radtke F., Tacchini-Cottier F., 2016/12/15. Scientific reports, 6 p. 39117. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6327A7D47779]
Metabolic communication in tumors: a new layer of immunoregulation for immune evasion.
Ho P.C., Liu P.S., 2016. Journal For Immunotherapy of Cancer, 4 p. 4. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_DD5E2FA95B5C]
 
Metabolic tug-of-war in tumors results in diminished T cell antitumor immunity.
Cheng W.C., Ho P.C., 2016. Oncoimmunology, 5 (4) pp. e1119355. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_054469C5F3CE]
 
Regulatory circuits of T cell function in cancer.
Speiser D.E., Ho P.C., Verdeil G., 2016. Nature Reviews. Immunology, 16 (10) pp. 599-611. Peer-reviewed.
[DOI][Pmid][serval:BIB_8F2CE0F06A85]
2015
 
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray J.P., Staron M.M., Shyer J.A., Ho P.C., Marshall H.D., Gray S.M., Laidlaw B.J., Araki K., Ahmed R., Kaech S.M. et al., 2015/10/20. Immunity, 43 (4) pp. 690-702. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E99535EA33C0]
 
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ho P.C., Bihuniak J.D., Macintyre A.N., Staron M., Liu X., Amezquita R., Tsui Y.C., Cui G., Micevic G., Perales J.C. et al., 2015/09/10. Cell, 162 (6) pp. 1217-1228. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_37B3D0EAAAF9]
 
IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity.
Cui G., Staron M.M., Gray S.M., Ho P.C., Amezquita R.A., Wu J., Kaech S.M., 2015/05/07. Cell, 161 (4) pp. 750-761. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DB78287233DC]
2014
 
BRAF-targeted therapy alters the functions of intratumoral CD4<sup>+</sup> T cells to inhibit melanoma progression.
Ho P.C., Kaech S.M., 2014/06/18. Oncoimmunology, 3 pp. e29126. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7C3678EE2D42]
 
Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ.
Ho P.C., Meeth K.M., Tsui Y.C., Srivastava B., Bosenberg M.W., Kaech S.M., 2014/06/15. Cancer research, 74 (12) pp. 3205-3217. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F7875BCF67D2]
2012
 
Biological activities of receptor-interacting protein 140 in adipocytes and metabolic diseases.
Ho P.C., Wei L.N., 2012/11. Current diabetes reviews, 8 (6) pp. 452-457. Peer-reviewed.
[Pmid][serval:BIB_7926EFF7E0DD]
 
Endothelin-1 promotes cytoplasmic accumulation of RIP140 through a ET(A)-PLCβ-PKCε pathway.
Ho P.C., Tsui Y.C., Lin Y.W., Persaud S.D., Wei L.N., 2012/04/04. Molecular and cellular endocrinology, 351 (2) pp. 176-183. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5452504C33B2]
 
NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance.
Ho P.C., Tsui Y.C., Feng X., Greaves D.R., Wei L.N., 2012/03/04. Nature immunology, 13 (4) pp. 379-386. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_782F81CF4A06]
 
Negative regulation of adiponectin secretion by receptor interacting protein 140 (RIP140).
Ho P.C., Wei L.N., 2012/01. Cellular signalling, 24 (1) pp. 71-76. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DAE87D031B96]
2011
 
Cytoplasmic receptor-interacting protein 140 (RIP140) interacts with perilipin to regulate lipolysis.
Ho P.C., Chuang Y.S., Hung C.H., Wei L.N., 2011/08. Cellular signalling, 23 (8) pp. 1396-1403. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D68189D09B30]
 
Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production.
Ho P.C., Chang K.C., Chuang Y.S., Wei L.N., 2011/05. FASEB journal, 25 (5) pp. 1758-1766. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38B1930CA3D9]
 
Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter.
Chuang Y.S., Huang W.H., Park S.W., Persaud S.D., Hung C.H., Ho P.C., Wei L.N., 2011/04. Stem cells, 29 (4) pp. 660-669. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CFEFC5ED8B13]
2009
 
A negative regulatory pathway of GLUT4 trafficking in adipocyte: new function of RIP140 in the cytoplasm via AS160.
Ho P.C., Lin Y.W., Tsui Y.C., Gupta P., Wei L.N., 2009/12. Cell metabolism, 10 (6) pp. 516-523. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_92591F2734B4]
 
HDAC3 as a molecular chaperone for shuttling phosphorylated TR2 to PML: a novel deacetylase activity-independent function of HDAC3.
Gupta P., Ho P.C., Ha S.G., Lin Y.W., Wei L.N., 2009. PloS one, 4 (2) pp. e4363. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E31150359498]
2008
 
Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation.
Ho P.C., Gupta P., Tsui Y.C., Ha S.G., Huq M., Wei L.N., 2008/10. Cellular signalling, 20 (10) pp. 1911-1919. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_09813B29D7AF]
 
Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression.
Gupta P., Ho P.C., Huq M.M., Ha S.G., Park S.W., Khan A.A., Tsai N.P., Wei L.N., 2008/08/12. Proceedings of the National Academy of Sciences of the United States of America, 105 (32) pp. 11424-11429. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B568741255C3]
 
PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation.
Gupta P., Ho P.C., Huq M.D., Khan A.A., Tsai N.P., Wei L.N., 2008/07/16. PloS one, 3 (7) pp. e2658. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_32B570616A7C]
 
Regulation of stress granule dynamics by Grb7 and FAK signalling pathway.
Tsai N.P., Ho P.C., Wei L.N., 2008/03/05. The EMBO journal, 27 (5) pp. 715-726. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_494A8AA751D5]
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