Nadège Zanou

Publications | Mémoires et thèses

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30 publications

En préparation
 
CDK4 deletion in mice prevents fat accumulation and increases endurance capacity through activation of estrogen-related receptor (ERR)-driven oxidative metabolism in skeletal muscle
Barquissau Valentin, Zanou Nadège, Geller Sarah, Castillo-Armengol Judit, Marzetta Flavia, Huber Katharina, Ziegler Dorian, Lopez-Mejia Isabel, Fernandez Joan Blanco, Roger Catherine et al..
[DOI][serval:BIB_2CA3F1A4A423]
 
RyR1 protein content is reduced in inflammatory and mitochondrial myopathies and induces ER stress
Vidal Jeremy, Fernandez Eric Aria, Wohlwend Martin, Laurila Pirkka-Pekka, Lopez Mejia Andrea, Ochala Julien, Lopez Mejia Isabel, Lobrinus Johannes Alexandre, Kayser Bengt, Place Nicolas et al..
[DOI][serval:BIB_CC8524DE5244]
 
CDK4 inactivation balances resistance to apoptosis with heightened metabolic sensitivity in triple negative breast cancer cells
Ziegler Dorian V., Leal-Esteban Lucia, Parashar Kanishka, Castro Wilson, Zanou Nadège, Huber Katharina, López-Alcalá Jaime, Berney Xavier Pascal, Malagón María M, Roger Catherine et al..
[DOI][serval:BIB_20CA91209F3E]
2025
 
CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer.
Ziegler D.V., Parashar K., Leal-Esteban L., López-Alcalá J., Castro W., Zanou N., Martinez-Carreres L., Huber K., Berney X.P., Malagón M.M. et al., 2025/01/09. Nature communications, 16 (1) p. 541. Peer-reviewed.
[DOI][Pmid][serval:BIB_C59FE7AA0BFC]
2024
BCL2L13 at endoplasmic reticulum-mitochondria contact sites regulates calcium homeostasis to maintain skeletal muscle function.
Grepper D., Tabasso C., Zanou N., Aguettaz AKF, Castro-Sepulveda M., Ziegler D.V., Lagarrigue S., Arribat Y., Martinotti A., Ebrahimi A. et al., 2024/08/16. iScience, 27 (8) p. 110510. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B2C6F7B17A6]
Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models.
De Masi A., Zanou N., Strotjohann K., Lee D., Lima T.I., Li X., Jeon J., Place N., Jung H.Y., Auwerx J., 2024/07. Advanced science, 11 (28) pp. e2305927. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0EBEAE2F135F]
Functional hypoxia reduces mitochondrial calcium uptake.
Donnelly C., Komlódi T., Cecatto C., Cardoso LHD, Compagnion A.C., Matera A., Tavernari D., Campiche O., Paolicelli R.C., Zanou N. et al., 2024/05. Redox biology, 71 p. 103037. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_2E8283116312]
Repeated sprint training in hypoxia induces specific skeletal muscle adaptations through S100A protein signaling.
Lanfranchi C., Willis S.J., Laramée L., Conde Alonso S., Pialoux V., Kayser B., Place N., Millet G.P., Zanou N., 2024/04/30. FASEB journal, 38 (8) pp. e23615. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E20962C33F3A]
Effect of 12 weeks of detraining and retraining on the cardiorespiratory fitness in a competitive master athlete: a case study.
Lepers R., Mater A., Assadi H., Zanou N., Gremeaux V., Place N., 2024. Frontiers in physiology, 15 p. 1508642. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B7E421C743FE]
2023
Ryanodine receptor type 1 content decrease-induced endoplasmic reticulum stress is a hallmark of myopathies.
Vidal J., Fernandez E.A., Wohlwend M., Laurila P.P., Lopez-Mejia A., Ochala J., Lobrinus A.J., Kayser B., Lopez-Mejia I.C., Place N. et al., 2023/12. Journal of cachexia, sarcopenia and muscle, 14 (6) pp. 2882-2897. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5FA8F26A1D9D]
Moderate Effects of Hypoxic Training at Low and Supramaximal Intensities on Skeletal Muscle Metabolic Gene Expression in Mice.
Drozdovska S., Zanou N., Lavier J., Mazzolai L., Millet G.P., Pellegrin M., 2023/10/21. Metabolites, 13 (10) p. 1103. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_41015932E21B]
2022
 
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila P.P., Wohlwend M., Imamura de Lima T., Luan P., Herzig S., Zanou N., Crisol B., Bou-Sleiman M., Porcu E., Gallart-Ayala H. et al., 2022/12. Nature aging, 2 (12) pp. 1159-1175. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_05ED6592DE02]
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila P.P., Luan P., Wohlwend M., Zanou N., Crisol B., Imamura de Lima T., Goeminne LJE, Gallart-Ayala H., Shong M., Ivanisevic J. et al., 2022/01/28. Science advances, 8 (4) pp. eabh4423. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_95F002D1A653]
2021
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity.
Zanou N., Dridi H., Reiken S., Imamura de Lima T., Donnelly C., De Marchi U., Ferrini M., Vidal J., Sittenfeld L., Feige J.N. et al., 2021/12/10. Nature communications, 12 (1) p. 7219. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B4985CA147A]
The Muscle-Brain Axis and Neurodegenerative Diseases: The Key Role of Mitochondria in Exercise-Induced Neuroprotection.
Burtscher J., Millet G.P., Place N., Kayser B., Zanou N., 2021/06/17. International journal of molecular sciences, 22 (12) p. 6479. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E543C44B1D59]
 
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy.
Luan P., D'Amico D., Andreux P.A., Laurila P.P., Wohlwend M., Li H., Imamura de Lima T., Place N., Rinsch C., Zanou N. et al., 2021/04/07. Science translational medicine, 13 (588) pp. eabb0319. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5CDD62173D83]
2019
 
Three weeks of sprint interval training improved high-intensity cycling performance and limited ryanodine receptor modifications in recreationally active human subjects.
Schlittler M., Neyroud D., Tanga C., Zanou N., Kamandulis S., Skurvydas A., Kayser B., Westerblad H., Place N., Andersson D.C., 2019/09. European journal of applied physiology, 119 (9) pp. 1951-1958. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DFC7FAB6C019]
2017
 
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia I.C., Lagarrigue S., Giralt A., Martinez-Carreres L., Zanou N., Denechaud P.D., Castillo-Armengol J., Chavey C., Orpinell M., Delacuisine B. et al., 2017. Molecular Cell, 68 (2) pp. 336-349.e6. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F02666506F7E]
2016
 
TRPV4 participates in pressure-induced inhibition of renin secretion by juxtaglomerular cells.
Seghers F., Yerna X., Zanou N., Devuyst O., Vennekens R., Nilius B., Gailly P., 2016/12/15. The Journal of physiology, 594 (24) pp. 7327-7340. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FA79029779B8]
 
Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells.
Lepannetier S., Zanou N., Yerna X., Emeriau N., Dufour I., Masquelier J., Muccioli G., Tajeddine N., Gailly P., 2016/12. Cell calcium, 60 (6) pp. 373-383. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_56F0FD9DD23A]
 
APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.
Stanga S., Zanou N., Audouard E., Tasiaux B., Contino S., Vandermeulen G., René F., Loeffler J.P., Clotman F., Gailly P. et al., 2016/05. FASEB journal, 30 (5) pp. 1696-1711. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B90F72A47146]
2015
 
Osmosensation in TRPV2 dominant negative expressing skeletal muscle fibres.
Zanou N., Mondin L., Fuster C., Seghers F., Dufour I., de Clippele M., Schakman O., Tajeddine N., Iwata Y., Wakabayashi S. et al., 2015/09/01. The Journal of physiology, 593 (17) pp. 3849-3863. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67D2D200F357]
2014
 
Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle.
Plaideau C., Lai Y.C., Kviklyte S., Zanou N., Löfgren L., Andersén H., Vertommen D., Gailly P., Hue L., Bohlooly-Y M. et al., 2014/11/20. Chemistry & biology, 21 (11) pp. 1497-1510. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0F273C4D3BA5]
2013
 
Skeletal muscle hypertrophy and regeneration: interplay between the myogenic regulatory factors (MRFs) and insulin-like growth factors (IGFs) pathways.
Zanou N., Gailly P., 2013/11. Cellular and molecular life sciences, 70 (21) pp. 4117-4130. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C253C8F8A807]
 
Androgen deprivation and androgen receptor competition by bicalutamide induce autophagy of hormone-resistant prostate cancer cells and confer resistance to apoptosis.
Boutin B., Tajeddine N., Vandersmissen P., Zanou N., Van Schoor M., Mondin L., Courtoy P.J., Tombal B., Gailly P., 2013/07. The Prostate, 73 (10) pp. 1090-1102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FEF3D64AE478]
2012
 
Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration.
Zanou N., Schakman O., Louis P., Ruegg U.T., Dietrich A., Birnbaumer L., Gailly P., 2012. Journal of Biological Chemistry, 287 (18) pp. 14524-14534.
[DOI][WoS][Pmid][serval:BIB_ECAA665B46B4]
2010
 
TRPC1: subcellular localization?
Tajeddine N., Zanou N., Van Schoor M., Lebacq J., Gailly P., 2010/01/29. The Journal of biological chemistry, 285 (5) pp. le1; author reply le2. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_79604F51D810]
 
Role of TRPC1 channel in skeletal muscle function.
Zanou N., Shapovalov G., Louis M., Tajeddine N., Gallo C., Van Schoor M., Anguish I., Cao M.L., Schakman O., Dietrich A. et al., 2010/01. American journal of physiology. Cell physiology, 298 (1) pp. C149-62. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A085EB00B0F5]
2009
 
Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions.
Zanou N., Iwata Y., Schakman O., Lebacq J., Wakabayashi S., Gailly P., 2009/11/19. FEBS letters, 583 (22) pp. 3600-3604. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B10C365393D1]
2008
 
TRPC1 regulates skeletal myoblast migration and differentiation.
Louis M., Zanou N., Van Schoor M., Gailly P., 2008/12/01. Journal of cell science, 121 (Pt 23) pp. 3951-3959. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DB611CFE2E1A]
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