Hector Gallart Ayala

Publications | Mémoires et thèses

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71 publications

Sous presse | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 |
 
ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH.
Liu Y.J., Kimura M., Li X., Sulc J., Wang Q., Rodríguez-López S., Scantlebery AML, Strotjohann K., Gallart-Ayala H., Vijayakumar A. et al. Journal of hepatology. Peer-reviewed.
 
Circulating amino acid signature features urea cycle alterations associated with coronary artery disease.
Prechtl L., Carrard J., Gallart-Ayala H., Borreggine R., Teav T., Königstein K., Wagner J., Knaier R., Infanger D., Streese L. et al., 2024/10/28. Scientific reports, 14 (1) p. 25848. Peer-reviewed.
 
Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards.
Torta F., Hoffmann N., Burla B., Alecu I., Arita M., Bamba T., Bennett SAL, Bertrand-Michel J., Brügger B., Cala M.P. et al., 2024/10/03. Nature communications, 15 (1) p. 8562. Peer-reviewed.
E2F transcription factor-1 modulates expression of glutamine metabolic genes in mouse embryonic fibroblasts and uterine sarcoma cells.
Huber K., Giralt A., Dreos R., Michenthaler H., Geller S., Barquissau V., Ziegler D.V., Tavernari D., Gallart-Ayala H., Krajina K. et al., 2024/06. Biochimica et biophysica acta. Molecular cell research, 1871 (5) p. 119721. Peer-reviewed.
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction.
Wohlwend M., Laurila P.P., Goeminne LJE, Lima T., Daskalaki I., Li X., von Alvensleben G., Crisol B., Mangione R., Gallart-Ayala H. et al., 2024/03/20. eLife, 12. Peer-reviewed.
Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in Drosophila.
Cavigliasso F., Savitsky M., Koval A., Erkosar B., Savary L., Gallart-Ayala H., Ivanisevic J., Katanaev V.L., Kawecki T.J., 2024/03. PLoS genetics, 20 (3) pp. e1011204. Peer-reviewed.
Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)-Protocol for a randomised controlled exercise trial.
Carrard J., Hofer M., Prechtl L., Fleischlin E., Huber M., Gallart-Ayala H., Teav T., Infanger D., Höchsmann C., Koehler K. et al., 2024. PloS one, 19 (5) pp. e0302477. Peer-reviewed.
Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila.
Erkosar B., Dupuis C., Cavigliasso F., Savary L., Kremmer L., Gallart-Ayala H., Ivanisevic J., Kawecki T.J., 2023/10/17. eLife, 12 pp. e92465. Peer-reviewed.
Experimental evolution of metabolism under nutrient restriction: enhanced amino acid catabolism and a key role of branched-chain amino acids
Cavigliasso F., Savary L., Spangenberg J. E, Gallart-Ayala H., Ivanisevic J., Kawecki T. J., 2023/05/18. Evolution Letters, 7 pp. 273–284. Peer-reviewed.
 
Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.
Lima T.I., Laurila P.P., Wohlwend M., Morel J.D., Goeminne LJE, Li H., Romani M., Li X., Oh C.M., Park D. et al., 2023/05/17. Science translational medicine, 15 (696) pp. eade6509. Peer-reviewed.
 
Omic-Scale High-Throughput Quantitative LC-MS/MS Approach for Circulatory Lipid Phenotyping in Clinical Research.
Medina J., Borreggine R., Teav T., Gao L., Ji S., Carrard J., Jones C., Blomberg N., Jech M., Atkins A. et al., 2023/02/14. Analytical chemistry, 95 (6) pp. 3168-3179. Peer-reviewed.
Divergence in metabolomic profile in clownfish and damselfish skin mucus
Heim S., Teav T., Gallart-Ayala H., Ivanisevic J., Salamin N., 2023/02/07. Frontiers in Ecology and Evolution, 11.
PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition.
Triscott J., Reist M., Küng L., Moselle F.C., Lehner M., Gallon J., Ravi A., Arora G.K., de Brot S., Lundquist M. et al., 2023/02/03. Science advances, 9 (5) pp. eade8641. Peer-reviewed.
Molecular insights into sex-specific metabolic alterations in Alzheimer's mouse brain using multi-omics approach.
Strefeler A., Jan M., Quadroni M., Teav T., Rosenberg N., Chatton J.Y., Guex N., Gallart-Ayala H., Ivanisevic J., 2023/01/09. Alzheimer's research & therapy, 15 (1) p. 8. Peer-reviewed.
 
Immunoediting instructs tumor metabolic reprogramming to support immune evasion.
Tsai C.H., Chuang Y.M., Li X., Yu Y.R., Tzeng S.F., Teoh S.T., Lindblad K.E., Di Matteo M., Cheng W.C., Hsueh P.C. et al., 2023/01/03. Cell metabolism, 35 (1) pp. 118-133.e7. Peer-reviewed.
 
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila P.P., Wohlwend M., Imamura de Lima T., Luan P., Herzig S., Zanou N., Crisol B., Bou-Sleiman M., Porcu E., Gallart-Ayala H. et al., 2022/12. Nature aging, 2 (12) pp. 1159-1175. Peer-reviewed.
A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation.
Ince Y.Ç., Krahmer J., Fiorucci A.S., Trevisan M., Galvão V.C., Wigger L., Pradervand S., Fouillen L., Van Delft P., Genva M. et al., 2022/10/10. Nature communications, 13 (1) p. 5659. Peer-reviewed.
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
Li Hao, Perino Alessia, Huang Qingyao, Von Alvensleben Giacomo V.G., Banaei-Esfahani Amir, Velazquez-Villegas Laura A., Gariani Karim, Korbelius Melanie, Bou Sleiman Maroun, Imbach Jéromine et al., 2022/10. Cell Metabolism, 34 (10) pp. 1594-1610.e4.
Investigating the circulating sphingolipidome response to a single high-intensity interval training session within healthy females and males in their twenties (SphingoHIIT): Protocol for a randomised controlled trial.
Carrard J., Angst T., Weber N., Bienvenue J., Infanger D., Streese L., Hinrichs T., Croci I., Schmied C., Gallart-Ayala H. et al., 2022/06. F1000Research, 11 p. 1565. Peer-reviewed.
Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.
ElMokh O., Matsumoto S., Biniecka P., Bellotti A., Schaeuble K., Piacente F., Gallart-Ayala H., Ivanisevic J., Stamenkovic I., Nencioni A. et al., 2022/04/08. Cell death & disease, 13 (4) p. 320. Peer-reviewed.
 
PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Raines L.N., Zhao H., Wang Y., Chen H.Y., Gallart-Ayala H., Hsueh P.C., Cao W., Koh Y., Alamonte-Loya A., Liu P.S. et al., 2022/03. Nature immunology, 23 (3) pp. 431-445. Peer-reviewed.
The Metabolic Signature of Cardiorespiratory Fitness: A Systematic Review.
Carrard J., Guerini C., Appenzeller-Herzog C., Infanger D., Königstein K., Streese L., Hinrichs T., Hanssen H., Gallart-Ayala H., Ivanisevic J. et al., 2022/03. Sports medicine, 52 (3) pp. 527-546. Peer-reviewed.
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila P.P., Luan P., Wohlwend M., Zanou N., Crisol B., Imamura de Lima T., Goeminne LJE, Gallart-Ayala H., Shong M., Ivanisevic J. et al., 2022/01/28. Science advances, 8 (4) pp. eabh4423. Peer-reviewed.
 
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study
Reinke Stacey N., Naz Shama, Chaleckis Romanas, Gallart-Ayala Hector, Kolmert Johan, Kermani Nazanin Z., Tiotiu Angelica, Broadhurst David I., Lundqvist Anders, Olsson Henric et al., 2022. European Respiratory Journal, 59 (6).
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G., Tsai C.H., Gallart-Ayala H., Yu Y.R., Franco F., Zaffalon L., Xie X., Li X., Xiao Z., Raines L.N. et al., 2021/11. Nature immunology, 22 (11) pp. 1403-1415. Peer-reviewed.
Sex-specific alterations in NAD+ metabolism in 3xTg Alzheimer's disease mouse brain assessed by quantitative targeted LC-MS.
van der Velpen V., Rosenberg N., Maillard V., Teav T., Chatton J.Y., Gallart-Ayala H., Ivanisevic J., 2021/10. Journal of neurochemistry, 159 (2) pp. 378-388. Peer-reviewed.
How Ceramides Orchestrate Cardiometabolic Health-An Ode to Physically Active Living.
Carrard J., Gallart-Ayala H., Weber N., Colledge F., Streese L., Hanssen H., Schmied C., Ivanisevic J., Schmidt-Trucksäss A., 2021/09/30. Metabolites, 11 (10) p. 675. Peer-reviewed.
 
The fate of orally administered sialic acid: First insights from patients with N-acetylneuraminic acid synthase deficiency and control subjects.
Tran C., Turolla L., Ballhausen D., Buros S.C., Teav T., Gallart-Ayala H., Ivanisevic J., Faouzi M., Lefeber D.J., Ivanovski I. et al., 2021/09. Molecular genetics and metabolism reports, 28 p. 100777. Peer-reviewed.
Metabolic View on Human Healthspan: A Lipidome-Wide Association Study.
Carrard J., Gallart-Ayala H., Infanger D., Teav T., Wagner J., Knaier R., Colledge F., Streese L., Königstein K., Hinrichs T. et al., 2021/04/30. Metabolites, 11 (5) p. 287. Peer-reviewed.
Metabolic Impairment in Coronary Artery Disease: Elevated Serum Acylcarnitines Under the Spotlights.
Gander J., Carrard J., Gallart-Ayala H., Borreggine R., Teav T., Infanger D., Colledge F., Streese L., Wagner J., Klenk C. et al., 2021. Frontiers in cardiovascular medicine, 8 p. 792350. Peer-reviewed.
The metabolic signature of cardiorespiratory fitness: a protocol for a systematic review and meta-analysis.
Carrard J., Guerini C., Appenzeller-Herzog C., Infanger D., Königstein K., Streese L., Hinrichs T., Hanssen H., Gallart-Ayala H., Ivanisevic J. et al., 2021. BMJ open sport & exercise medicine, 7 (1) pp. e001008. Peer-reviewed.
Single-Step Extraction Coupled with Targeted HILIC-MS/MS Approach for Comprehensive Analysis of Human Plasma Lipidome and Polar Metabolome.
Medina J., van der Velpen V., Teav T., Guitton Y., Gallart-Ayala H., Ivanisevic J., 2020/12/02. Metabolites, 10 (12) p. 495. Peer-reviewed.
 
Metabolomics meets lipidomics: Assessing the small molecule component of metabolism.
Gallart-Ayala H., Teav T., Ivanisevic J., 2020/12. BioEssays, 42 (12) pp. e2000052. Peer-reviewed.
Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models.
Hadadi N., Pandey V., Chiappino-Pepe A., Morales M., Gallart-Ayala H., Mehl F., Ivanisevic J., Sentchilo V., Meer JRV, 2020. NPJ systems biology and applications, 6 (1) p. 1. Peer-reviewed.
Systemic and central nervous system metabolic alterations in Alzheimer's disease
van der Velpen Vera, Teav Tony, Gallart-Ayala Héctor, Mehl Florence, Konz Ioana, Clark Christopher, Oikonomidi Aikaterini, Peyratout Gwendoline, Henry Hugues, Delorenzi Mauro et al., 2019/12. Alzheimer's Research & Therapy, 11 (1). Peer-reviewed.
MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma.
Oliynyk G., Ruiz-Pérez M.V., Sainero-Alcolado L., Dzieran J., Zirath H., Gallart-Ayala H., Wheelock C.E., Johansson H.J., Nilsson R., Lehtiö J. et al., 2019/11/22. iScience, 21 pp. 188-204. Peer-reviewed.
 
Merged Targeted Quantification and Untargeted Profiling for Comprehensive Assessment of Acylcarnitine and Amino Acid Metabolism.
Teav T., Gallart-Ayala H., van der Velpen V., Mehl F., Henry H., Ivanisevic J., 2019/09/17. Analytical chemistry, 91 (18) pp. 11757-11769. Peer-reviewed.
 
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cianciaruso C., Beltraminelli T., Duval F., Nassiri S., Hamelin R., Mozes A., Gallart-Ayala H., Ceada Torres G., Torchia B., Ries C.H. et al., 2019/06/04. Cell reports, 27 (10) pp. 3062-3080.e11. Peer-reviewed.
 
A global HILIC-MS approach to measure polar human cerebrospinal fluid metabolome: Exploring gender-associated variation in a cohort of elderly cognitively healthy subjects.
Gallart-Ayala H., Konz I., Mehl F., Teav T., Oikonomidi A., Peyratout G., van der Velpen V., Popp J., Ivanisevic J., 2018/12/11. Analytica chimica acta, 1037 pp. 327-337. Peer-reviewed.
LC-HRMS data as a result of untargeted metabolomic profiling of human cerebrospinal fluid.
Mehl F., Gallart-Ayala H., Konz I., Teav T., Oikonomidi A., Peyratout G., van der Velpen V., Popp J., Ivanisevic J., 2018/12. Data in brief, 21 pp. 1358-1362. Peer-reviewed.
 
Metabolomics: a tool to characterize the effect of phthalates and bisphenol A
Gómez Cristina, Gallart-Ayala Hector, 2018/12. Environmental Reviews, 26 (4) pp. 351-357.
 
New in vitro model derived from brain-specific Mut-/- mice confirms cerebral ammonium accumulation in methylmalonic aciduria.
Remacle N., Forny P., Cudré-Cung H.P., Gonzalez-Melo M., do Vale-Pereira S., Henry H., Teav T., Gallart-Ayala H., Braissant O., Baumgartner M. et al., 2018/08. Molecular genetics and metabolism, 124 (4) pp. 266-277. Peer-reviewed.
 
Development of an LC-HRMS metabolomics method with high specificity for metabolite identification using all ion fragmentation (AIF) acquisition
Naz Shama, Gallart-Ayala Hector, Reinke Stacey, Mathon Caroline, Blankley Richard, Chaleckis Romanas, Wheelock Craig Edward, 2017/06/22. Analytical Chemistry.
 
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
Lefaudeux D., De Meulder B., Loza M.J., Peffer N., Rowe A., Baribaud F., Bansal A.T., Lutter R., Sousa A.R., Corfield J. et al., 2017/06. The Journal of allergy and clinical immunology, 139 (6) pp. 1797-1807. Peer-reviewed.
 
Metabolomics analysis identifies different metabotypes of asthma severity.
Reinke S.N., Gallart-Ayala H., Gómez C., Checa A., Fauland A., Naz S., Kamleh M.A., Djukanović R., Hinks T.S., Wheelock C.E., 2017/03. The European respiratory journal, 49 (3).
 
A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing.
Roci I., Gallart-Ayala H., Watrous J., Jain M., Wheelock C.E., Nilsson R., 2017/02/04. Journal of visualized experiments : JoVE 120.
 
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Loza M.J., Djukanovic R., Chung K.F., Horowitz D., Ma K., Branigan P., Barnathan E.S., Susulic V.S., Silkoff P.E., Sterk P.J. et al., 2016/12/15. Respiratory research, 17 (1) p. 165.
 
Ultra-high-performance liquid chromatography-high-resolution mass spectrometry based metabolomics as a strategy for beer characterization : Metabolomics in beer characterization
Gallart-Ayala Hector, Kamleh Muhammad Anas, Hernández-Cassou Santiago, Saurina Javier, Checa Antonio, 2016/07. Journal of the Institute of Brewing, 122 (3) pp. 430-436.
 
Metabolite Profiling and Stable Isotope Tracing in Sorted Subpopulations of Mammalian Cells.
Roci I., Gallart-Ayala H., Schmidt A., Watrous J., Jain M., Wheelock C.E., Nilsson R., 2016/03/01. Analytical chemistry, 88 (5) pp. 2707-2713.
 
Told through the wine: A liquid chromatography-mass spectrometry interplatform comparison reveals the influence of the global approach on the final annotated metabolites in non-targeted metabolomics.
Díaz R., Gallart-Ayala H., Sancho J.V., Nuñez O., Zamora T., Martins C.P., Hernández F., Hernández-Cassou S., Saurina J., Checa A., 2016/02/12. Journal of chromatography. A, 1433 pp. 90-97.
 
Hydrophilic interaction (HILIC) and reverse phase liquid chromatography (RPLC)–high resolution MS for characterizing lipids profile disruption in serum of anabolic implanted bovines
Nzoughet J. Kouassi, Gallart-Ayala H., Biancotto G., Hennig K., Dervilly-Pinel G., Le Bizec B., 2015/12. Metabolomics, 11 (6) pp. 1884-1895.
 
Potential of mass spectrometry metabolomics for chemical food safety.
Gallart-Ayala H., Chéreau S., Dervilly-Pinel G., Le Bizec B., 2015. Bioanalysis, 7 (1) pp. 133-146.
 
New branches in the degradation pathway of monochlorocatechols by Aspergillus nidulans: a metabolomics analysis.
Martins T.M., Núñez O., Gallart-Ayala H., Leitão M.C., Galceran M.T., Silva Pereira C., 2014/03/15. Journal of hazardous materials, 268 pp. 264-272.
 
Versatile lipid profiling by liquid chromatography-high resolution mass spectrometry using all ion fragmentation and polarity switching. Preliminary application for serum samples phenotyping related to canine mammary cancer.
Gallart-Ayala H., Courant F., Severe S., Antignac J.P., Morio F., Abadie J., Le Bizec B., 2013/09/24. Analytica chimica acta, 796 pp. 75-83.
 
State-of-the-art in fast liquid chromatography-mass spectrometry for bio-analytical applications.
Núñez O., Gallart-Ayala H., Martins C.P., Lucci P., Busquets R., 2013/05/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 927 pp. 3-21.
 
The response of Mucor plumbeus to pentachlorophenol: a toxicoproteomics study.
Carvalho M.B., Martins I., Medeiros J., Tavares S., Planchon S., Renaut J., Núñez O., Gallart-Ayala H., Galceran M.T., Hursthouse A. et al., 2013/01/14. Journal of proteomics, 78 pp. 159-171.
 
Strategies for the multi-residue analysis of 100 pesticides by liquid chromatography-triple quadrupole mass spectrometry.
Núñez O., Gallart-Ayala H., Ferrer I., Moyano E., Galceran M.T., 2012/08/03. Journal of chromatography. A, 1249 pp. 164-180.
 
Liquid Chromatography Coupled to Electrochemical Detection and Mass Spectrometry for the Determination of Phenolic Compounds in Food and Beverages
Cortina-Puig Montserrat, Gallart-Ayala Hector, Lacorte Sílvia, 2012/08/01. Current Analytical Chemistry, 8 (4) pp. 436-455.
 
Atmospheric pressure photoionization mass spectrometry of fullerenes.
Núñez O., Gallart-Ayala H., Martins C.P., Moyano E., Galceran M.T., 2012/06/19. Analytical chemistry, 84 (12) pp. 5316-5326.
 
New trends in fast liquid chromatography for food and environmental analysis.
Núñez O., Gallart-Ayala H., Martins C.P., Lucci P., 2012/03/09. Journal of chromatography. A, 1228 pp. 298-323.
 
Degradation pathway of pentachlorophenol by Mucor plumbeus involves phase II conjugation and oxidation-reduction reactions.
Carvalho M.B., Tavares S., Medeiros J., Núñez O., Gallart-Ayala H., Leitão M.C., Galceran M.T., Hursthouse A., Pereira C.S., 2011/12/30. Journal of hazardous materials, 198 pp. 133-142.
 
Preventing false negatives with high-resolution mass spectrometry: the benzophenone case.
Gallart-Ayala H., Nuñez O., Moyano E., Galceran M.T., Martins C.P., 2011/10/30. Rapid communications in mass spectrometry : RCM, 25 (20) pp. 3161-3166.
 
Fast liquid chromatography-tandem mass spectrometry for the analysis of bisphenol A-diglycidyl ether, bisphenol F-diglycidyl ether and their derivatives in canned food and beverages.
Gallart-Ayala H., Moyano E., Galceran M.T., 2011/03/25. Journal of chromatography. A, 1218 (12) pp. 1603-1610.
 
Analysis of UV ink photoinitiators in packaged food by fast liquid chromatography at sub-ambient temperature coupled to tandem mass spectrometry.
Gallart-Ayala H., Núñez O., Moyano E., Galceran M.T., 2011/01/21. Journal of chromatography. A, 1218 (3) pp. 459-466.
 
Analysis of bisphenols in soft drinks by on-line solid phase extraction fast liquid chromatography-tandem mass spectrometry.
Gallart-Ayala H., Moyano E., Galceran M.T., 2011/01/10. Analytica chimica acta, 683 (2) pp. 227-233.
 
Multiple-stage mass spectrometry analysis of bisphenol A diglycidyl ether, bisphenol F diglycidyl ether and their derivatives.
Gallart-Ayala H., Moyano E., Galceran M.T., 2010/12/15. Rapid communications in mass spectrometry : RCM, 24 (23) pp. 3469-3477.
 
On-line solid phase extraction fast liquid chromatography-tandem mass spectrometry for the analysis of bisphenol A and its chlorinated derivatives in water samples.
Gallart-Ayala H., Moyano E., Galceran M.T., 2010/05/21. Journal of chromatography. A, 1217 (21) pp. 3511-3518.
 
Field-amplified sample injection-micellar electrokinetic capillary chromatography for the analysis of bisphenol A, bisphenol F, and their diglycidyl ethers and derivatives in canned soft drinks.
Gallart-Ayala H., Núñez O., Moyano E., Galceran M.T., 2010/05. Electrophoresis, 31 (9) pp. 1550-1559.
 
Recent advances in mass spectrometry analysis of phenolic endocrine disruptors and related compounds.
Gallart-Ayala H., Moyano E., Galceran M.T., 2010. Mass spectrometry reviews, 29 (5) pp. 776-805.
 
Liquid chromatography/tandem mass spectrometry (highly selective selected reaction monitoring) for the analysis of isopropylthioxanthone in packaged food.
Gallart-Ayala H., Moyano E., Galceran M.T., 2008/10/24. Journal of chromatography. A, 1208 (1-2) pp. 182-188.
 
Liquid chromatography/multi-stage mass spectrometry of bisphenol A and its halogenated derivatives.
Gallart-Ayala H., Moyano E., Galceran M.T., 2007. Rapid communications in mass spectrometry : RCM, 21 (24) pp. 4039-4048.
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