Vincent Desfontaine

Publications | Mémoires et thèses

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9 publications

2023 | 2022 | 2020 | 2019 |
2023
Population pharmacokinetic modelling to characterize the effect of chronic kidney disease on tenofovir exposure after tenofovir alafenamide administration.
Thoueille P., Alves Saldanha S., Desfontaine V., Kusejko K., Courlet P., Andre P., Cavassini M., Decosterd L.A., Buclin T., Guidi M. et al., 2023/06/01. The Journal of antimicrobial chemotherapy, 78 (6) pp. 1433-1443. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_449BF24E5A20]
Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies.
Biniecka P., Matsumoto S., Belotti A., Joussot J., Bai J.F., Majjigapu S.R., Thoueille P., Spaggiari D., Desfontaine V., Piacente F. et al., 2023/02/16. Molecules, 28 (4) p. 1897. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9D877CB69A0A]
Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V., Guinchard S., Marques S., Vocat A., Moulfi F., Versace F., Huser-Pitteloud J., Ivanyuk A., Bardinet C., Makarov V. et al., 2023/01/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1215 p. 123555. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_405A2D6AF487]
Development and validation of a liquid chromatography coupled to tandem mass spectrometry method for the monitoring of temsavir plasma concentrations in people living with HIV.
Thoueille P., Seybold U., Decosterd L.A., Desfontaine V., 2023/01/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1214 p. 123575. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0B73DC88085D]
2022
 
A battery of tandem mass spectrometry assays with stable isotope-dilution for the quantification of 15 anti-tuberculosis drugs and two metabolites in patients with susceptible-, multidrug-resistant- and extensively drug-resistant tuberculosis.
Mercier T., Desfontaine V., Cruchon S., Da Silva Pereira Clara J.A., Briki M., Mazza-Stalder J., Kajkus A., Burger R., Suttels V., Buclin T. et al., 2022/11/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1211 p. 123456. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8BD27ECE6B02]
 
Safety, tolerability and pharmacokinetic profile of Macozinone (PBTZ169) formulated as native crystal powder: multiple ascendingdoses, phase-Ib trial in healthy volunteers
Chtioui H., Prod'Hom S., Desfontaine V., André P., Moulfi F., Bardinet C., Abo-Loha C., Tessieras J., Rothuizen L.E., Diezi L. et al., 2022. dans 15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT) - June 2022 Athens. European Journal of Clinical Pharmacology, 2022, 78: 1-163.
[serval:BIB_F1F116FD908F]
2020
Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.
Courlet P., Alves Saldanha S., Cavassini M., Marzolini C., Choong E., Csajka C., Günthard H.F., André P., Buclin T., Desfontaine V. et al., 2020/06. Journal of mass spectrometry, 55 (6) pp. e4506. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1D794571C1B2]
2019
 
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Courlet P., Spaggiari D., Desfontaine V., Cavassini M., Alves Saldanha S., Buclin T., Marzolini C., Csajka C., Decosterd L.A., 2019/09/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1125 p. 121733. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_00B59FADA800]
Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma.
Spaggiari D., Desfontaine V., Cruchon S., Guinchard S., Vocat A., Blattes E., Pitteloud J., Ciullini L., Bardinet C., Ivanyuk A. et al., 2019. PloS one, 14 (5) pp. e0217139. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7C866ED75CDD]
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