Nicolas Fasel

Publications | Mémoires et thèses

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126 publications

2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2006 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1987 | 1986 | 1985 | 1983 | 1982 | 1980 |
2022
 
The Dangerous Liaisons in the Oxidative Stress Response to Leishmania Infection.
Reverte M., Snäkä T., Fasel N., 2022/03/28. Pathogens, 11 (4) p. 409. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2097C71271EF]
Dissection of the macrophage response towards infection by the Leishmania-viral endosymbiont duo and dynamics of the type I interferon response.
Bekkar A., Isorce N., Snäkä T., Claudinot S., Desponds C., Kopelyanskiy D., Prével F., Reverte M., Xenarios I., Fasel N. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941888. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8E5B725F389C]
In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B., Reverte M., Ronet C., Prevel F., Morgenthaler F.D., Desponds C., Lye L.F., Owens K.L., Scarpellino L., Dubey L.K. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941860. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2B104E1E8C7E]
Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont.
Kopelyanskiy D., Desponds C., Prevel F., Rossi M., Migliorini R., Snäkä T., Eren R.O., Claudinot S., Lye L.F., Pasparakis M. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 944819. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A72D8B03FFC4]
Sex-Biased Control of Inflammation and Metabolism by a Mitochondrial Nod-Like Receptor.
Snäkä T., Bekkar A., Desponds C., Prével F., Claudinot S., Isorce N., Teixeira F., Grasset C., Xenarios I., Lopez-Mejia I.C. et al., 2022. Frontiers in immunology, 13 p. 882867. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6C22CA5A408C]
2021
 
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
Reverte Marta, Eren Remzi Onur, Jha Baijayanti, Desponds Chantal, Snäkä Tiia, Prevel Florence, Isorce Nathalie, Lye Lon-Fye, Owens Katherine L., Gazos Lopes Ulisses et al., 2021/03/25. PLOS Pathogens, 17 (3) pp. e1009422.
[DOI][WoS][Pmid][serval:BIB_0AB06B72AE21]
2020
Viruses of protozoan parasites and viral therapy: Is the time now right?
Barrow P., Dujardin J.C., Fasel N., Greenwood A.D., Osterrieder K., Lomonossoff G., Fiori P.L., Atterbury R., Rossi M., Lalle M., 2020/09/29. Virology journal, 17 (1) p. 142. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C4D5A7E05A6B]
 
Viral Double-Stranded RNA Detection by DNase I and Nuclease S1 digestions in Leishmania parasites.
Isorce N., Fasel N., 2020/05/05. Bio-protocol, 10 (9) pp. e3598. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E819D1295762]
 
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases.
Minina E.A., Staal J., Alvarez V.E., Berges J.A., Berman-Frank I., Beyaert R., Bidle K.D., Bornancin F., Casanova M., Cazzulo J.J. et al., 2020/03/05. Molecular cell, 77 (5) pp. 927-929. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DC38FFDBB184]
Behind the Scenes: Nod-Like Receptor X1 Controls Inflammation and Metabolism.
Snäkä T., Fasel N., 2020. Frontiers in cellular and infection microbiology, 10 p. 609812. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9F6D9AD00CD7]
2019
 
Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.
Rath C.T., Schnellrath L.C., Damaso C.R., de Arruda L.B., Vasconcelos PFDC, Gomes C., Laurenti M.D., Calegari Silva T.C., Vivarini Á.C., Fasel N. et al., 2019/06. PLoS neglected tropical diseases, 13 (6) pp. e0007500. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_75870B3A26CF]
 
TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.
Ronet C., Passelli K., Charmoy M., Scarpellino L., Myburgh E., Hauyon La Torre Y., Turco S., Mottram J.C., Fasel N., Luther S.A. et al., 2019/06. The Journal of investigative dermatology, 139 (6) pp. 1318-1328. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8AC775CA2A74]
Leishmania Parasite Quantification by Bioluminescence in Murine Models
Reverte Marta, Fasel Nicolas, 2019. BIO-PROTOCOL, 9 (22).
[URN][DOI][WoS][serval:BIB_2144CB5E6247]
2018
The criminal association of Leishmania parasites and viruses.
Rossi M., Fasel N., 2018/12. Current opinion in microbiology, 46 pp. 65-72. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_02E69DE6AF21]
Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): a novel parasite evasion mechanism.
Calegari-Silva T.C., Vivarini Á.C., Pereira RMS, Dias-Teixeira K.L., Rath C.T., Pacheco ASS, Silva GBL, Pinto CAS, Dos Santos J.V., Saliba A.M. et al., 2018/07. European journal of immunology, 48 (7) pp. 1188-1198. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BD77F8A82A7]
How to master the host immune system? Leishmania parasites have the solutions!
Rossi M., Fasel N., 2018/03/10. International immunology, 30 (3) pp. 103-111. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8774637093C2]
Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite <i>Leishmania</i>.
Grybchuk D., Akopyants N.S., Kostygov A.Y., Konovalovas A., Lye L.F., Dobson D.E., Zangger H., Fasel N., Butenko A., Frolov A.O. et al., 2018/01/16. Proceedings of the National Academy of Sciences of the United States of America, 115 (3) pp. E506-E515. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C3DDB4066142]
Development of a semi-automated image-based high-throughput drug screening system.
Eren R.O., Kopelyanskiy D., Moreau D., Chapalay J.B., Chambon M., Turcatti G., Lye L.F., Beverley S.M., Fasel N., 2018/01/01. Frontiers in bioscience, 10 pp. 242-253. Peer-reviewed.
[URN][Pmid][serval:BIB_EC1B59732AE2]
Guidelines and recommendations on yeast cell death nomenclature
Carmona-Gutierez D, Fasel N, 2018. Microbial Cell, 5 (1) pp. 4-31. Peer-reviewed.
[URN][DOI][serval:BIB_4C2F0F02B2F3]
Importance of polyphosphate in the <i>Leishmania</i> life cycle.
Kohl K., Zangger H., Rossi M., Isorce N., Lye L.F., Owens K.L., Beverley S.M., Mayer A., Fasel N., 2018. Microbial Cell, 5 (8) pp. 371-384. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2707EAA051B6]
Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β.
Hartley M.A., Eren R.O., Rossi M., Prevel F., Castiglioni P., Isorce N., Desponds C., Lye L.F., Beverley S.M., Drexler S.K. et al., 2018. Microbial Cell, 5 (3) pp. 137-149. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_7AE1E45D5F8B]
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
Chennupati V., Veiga D.F., Maslowski K.M., Andina N., Tardivel A., Yu E.C., Stilinovic M., Simillion C., Duchosal M.A., Quadroni M. et al., 2018. The Journal of Clinical Investigation, 128 (4) pp. 1597-1614. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1F54AD670B3B]
2017
Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis.
Dias-Teixeira K.L., Calegari-Silva T.C., Medina J.M., Vivarini Á.C., Cavalcanti Á., Teteo N., Santana AKM, Real F., Gomes C.M., Pereira RMS et al., 2017/12/06. Scientific reports, 7 (1) p. 17074. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E02D5E2D0E4B]
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter.
Klompmaker S.H., Kohl K., Fasel N., Mayer A., 2017/12/01. Nature communications, 8 (1) p. 1879. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_578DBAD79CB3]
Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.
Rossi M., Castiglioni P., Hartley M.A., Eren R.O., Prével F., Desponds C., Utzschneider D.T., Zehn D., Cusi M.G., Kuhlmann F.M. et al., 2017/05/09. Proceedings of the National Academy of Sciences of the United States of America, 114 (19) pp. 4987-4992. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1563502F5904]
 
Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.
Kuhlmann F.M., Robinson J.I., Bluemling G.R., Ronet C., Fasel N., Beverley S.M., 2017/01/31. Proceedings of the National Academy of Sciences of the United States of America, 114 (5) pp. E811-E819. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9466129FAB72]
Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid.
Castiglioni P., Hartley M.A., Rossi M., Prevel F., Desponds C., Utzschneider D.T., Eren R.O., Zangger H., Brunner L., Collin N. et al., 2017. PLoS Neglected Tropical Diseases, 11 (1) pp. e0005240. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_18963158FCAB]
Macrophage Survival Assay Using High Content Microscopy
Eren R.O., Fasel N., 2017. Bio-protocol, 7 (16) pp. e2509. Peer-reviewed.
[URN][DOI][serval:BIB_4B76DFD4ED3B]
Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis
Vivarini Á.C., Calegari-Silva T.C., Saliba A.M., Boaventura V.S., França-Costa J., Khouri R., Dierckx T., Dias-Teixeira K. L., Fasel N., Barral Aldina M.P. et al., 2017. Frontiers in Immunology, 8 p. 1127. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_013A41738B07]
2016
Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response.
Brettmann E.A., Shaik J.S., Zangger H., Lye L.F., Kuhlmann F.M., Akopyants N.S., Oschwald D.M., Owens K.L., Hickerson S.M., Ronet C. et al., 2016/10/25. Proceedings of the National Academy of Sciences of the United States of America, 113 (43) pp. 11998-12005. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0768C7F7DFC1]
Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence.
Eren R.O., Reverte M., Rossi M., Hartley M.A., Castiglioni P., Prevel F., Martin R., Desponds C., Lye L.F., Drexler S.K. et al., 2016/09/14. Cell host & microbe, 20 (3) pp. 318-328. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_58680551DAFF]
Raptor hunted by caspases.
Martin R., Thome M., Martinon F., Fasel N., 2016/06/02. Cell death & disease, 7 (6) pp. e2242. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F08DA0F683EB]
A functional BH3 domain in an aquaporin from Leishmania infantum.
Genes C.M., de Lucio H., González V.M., Sánchez-Murcia P.A., Rico E., Gago F., Fasel N., Jiménez-Ruiz A., 2016. Cell Death Discovery, 2 p. 16043. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_2E2A6BEB3117]
Caspase-mediated cleavage of raptor participates in the inactivation of mTORC1 during cell death.
Martin R., Desponds C., Eren R.O., Quadroni M., Thome M., Fasel N., 2016. Cell Death Discovery, 2 p. 16024. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C5D8230CED35]
Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A.
Hartley M.A., Bourreau E., Rossi M., Castiglioni P., Eren R.O., Prevel F., Couppié P., Hickerson S.M., Launois P., Beverley S.M. et al., 2016. PLoS Pathogens, 12 (9) pp. e1005852. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A071D03EE498]
 
Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic Relapse.
Bourreau E., Ginouves M., Prévot G., Hartley M.A., Gangneux J.P., Robert-Gangneux F., Dufour J., Sainte-Marie D., Bertolotti A., Pratlong F. et al., 2016. Journal of Infectious Diseases, 213 (1) pp. 105-111. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C7B01273E737]
Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus.
Parmentier L., Cusini A., Müller N., Zangger H., Hartley M.A., Desponds C., Castiglioni P., Dubach P., Ronet C., Beverley S.M. et al., 2016. American Journal of Tropical Medicine and Hygiene, 94 (4) pp. 840-843. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7E8DF9B328A6]
Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection - Future Perspectives.
Dias-Teixeira K.L., Pereira R.M., Silva J.S., Fasel N., Aktas B.H., Lopes U.G., 2016. Frontiers In Immunology, 7 p. 283. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_92413F78E100]
2015
Implication of different domains of the Leishmania major metacaspase in cell death and autophagy.
Casanova M., Gonzalez I.J., Sprissler C., Zalila H., Dacher M., Basmaciyan L., Späth G.F., Azas N., Fasel N., 2015. Cell Death and Disease, 6 pp. e1933. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_97502941E4E6]
2014
 
Cross-presenting dendritic cells are required for control of Leishmania major infection.
Ashok D., Schuster S., Ronet C., Rosa M., Mack V., Lavanchy C., Marraco S.F., Fasel N., Murphy K.M., Tacchini-Cottier F. et al., 2014. European Journal of Immunology, 44 (5) pp. 1422-1432.
[DOI][WoS][Pmid][serval:BIB_465FF447B9AD]
Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response.
Zangger H., Hailu A., Desponds C., Lye L.F., Akopyants N.S., Dobson D.E., Ronet C., Ghalib H., Beverley S.M., Fasel N., 2014. PLoS Neglected Tropical Diseases, 8 (4) pp. e2836.
[URN][DOI][WoS][Pmid][serval:BIB_41643375CE22]
Leishmania metacaspase: an arginine-specific peptidase.
Martin R., Gonzalez I., Fasel N., 2014. Methods in Molecular Biology, 1133 pp. 189-202. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B3F360C931E2]
MyD88 and TLR9 dependent immune responses mediate resistance to Leishmania guyanensis infections, irrespective of Leishmania RNA virus burden.
Ives A., Masina S., Castiglioni P., Prével F., Revaz-Breton M., Hartley M.A., Launois P., Fasel N., Ronet C., 2014. PLoS One, 9 (5) pp. e96766.
[URN][DOI][WoS][Pmid][serval:BIB_B423F40036EF]
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Hartley M.A., Drexler S., Ronet C., Beverley S.M., Fasel N., 2014. Trends in Parasitology, 30 (8) pp. 412-422.
[URN][DOI][WoS][Pmid][serval:BIB_D4BCA71B0F2E]
2013
Detection of Leishmania RNA virus in Leishmania parasites.
Zangger H., Ronet C., Desponds C., Kuhlmann F.M., Robinson J., Hartley M.A., Prevel F., Castiglioni P., Pratlong F., Bastien P. et al., 2013. PLoS Neglected Tropical Diseases, 7 (1) pp. e2006.
[URN][DOI][WoS][Pmid][serval:BIB_E43BDA8FBC99]
 
Role of Toll-Like Receptor 9 Signaling in Experimental Leishmania braziliensis Infection.
Weinkopff T., Mariotto A., Simon G., Hauyon-La Torre Y., Auderset F., Schuster S., Zangger H., Fasel N., Barral A., Tacchini-Cottier F., 2013. Infection and Immunity, 81 (5) pp. 1575-1584.
[DOI][WoS][Pmid][serval:BIB_F092C2E76EAC]
 
The therapeutic potential of immune cross-talk in leishmaniasis.
Hartley M.A., Kohl K., Ronet C., Fasel N., 2013. Clinical Microbiology and Infection, 19 (2) pp. 119-130.
[URN][DOI][WoS][Pmid][serval:BIB_954DC4DB3EFA]
2012
 
Backseat drivers: the hidden influence of microbial viruses on disease.
Hartley M.A., Ronet C., Fasel N., 2012. Current Opinion in Microbiology, 15 (4) pp. 538-545. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8EBB90AB458E]
Leishmania RNA virus: when the host pays the toll.
Hartley M.A., Ronet C., Zangger H., Beverley S.M., Fasel N., 2012. Frontiers in Cellular and Infection Microbiology, 2 p. 99.
[URN][DOI][WoS][Pmid][serval:BIB_8945E9A0E9AD]
2011
Are protozoan metacaspases potential parasite killers?
Meslin B., Zalila H., Fasel N., Picot S., Bienvenu A.L., 2011. Parasites and Vectors, 4 pp. 26-32.
[URN][DOI][WoS][Pmid][serval:BIB_FAEC08ECD46B]
Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis.
Ives A., Ronet C., Prevel F., Ruzzante G., Fuertes-Marraco S., Schutz F., Zangger H., Revaz-Breton M., Lye L.F., Hickerson S.M. et al., 2011. Science, 331 (6018) pp. 775-778.
[URN][DOI][WoS][Pmid][serval:BIB_8FAE2070D6E0]
 
Muco-cutaneous leishmaniasis in the New World: The ultimate subversion.
Ronet C., Beverley S.M., Fasel N., 2011. Virulence, 2 (6) pp. 547-552.
[DOI][WoS][Pmid][serval:BIB_27E4CD94CE76]
Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death.
Meslin B., Beavogui A.H., Fasel N., Picot S., 2011. PLoS One, 6 (8) pp. e23867.
[URN][DOI][WoS][Pmid][serval:BIB_57F5537D6872]
Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major.
Zalila H., González I.J., El-Fadili A.K., Delgado M.B., Desponds C., Schaff C., Fasel N., 2011. Molecular Microbiology, 79 (1) pp. 222-239.
[URN][DOI][WoS][Pmid][serval:BIB_E32299FE64F3]
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
Fuertes Marraco S.A., Scott C.L., Bouillet P., Ives A., Masina S., Vremec D., Jansen E.S., O'Reilly L.A., Schneider P., Fasel N. et al., 2011. PLoS One, 6 (6) pp. e20189.
[URN][DOI][WoS][Pmid][serval:BIB_C67177D06725]
Un virus, hôte indésirable de L. guyanensis, détermine la gravité de la forme mucocutanée de la leishmaniose [Mucocutaneous leishmaniasis and an undesired passenger].
Ronet C., Beverley S.M., Fasel N., 2011. Médecine Sciences : M/S, 27 (11) pp. 924-926.
[URN][DOI][WoS][Pmid][serval:BIB_10455CDCCBCA]
2010
Apoptotic markers in protozoan parasites.
Jiménez-Ruiz A., Alzate J.F., Macleod E.T., Lüder C.G., Fasel N., Hurd H., 2010. Parasites and Vectors, 3 p. 104.
[URN][DOI][WoS][Pmid][serval:BIB_42C7F8FDC79A]
Cathepsin B-like and cell death in the unicellular human pathogen Leishmania.
El-Fadili A.K., Zangger H., Desponds C., Gonzalez I.J., Zalila H., Schaff C., Ives A., Masina S., Mottram J.C., Fasel N., 2010. Cell Death and Disease, 1 (9) pp. e71.
[URN][DOI][WoS][Pmid][serval:BIB_1CDC93F3BF21]
 
Immune responses to Leishmania guyanensis infection in humans and animal models
Ronet C., Ives A., Bourreau E., Fasel N., Launois P., Masina S., 2010. pp. 165-176 dans Jirillo E., Brandonisio O. (eds.) Protozoa chap. 11, Bentham eBooks.
[serval:BIB_988CEC8D2BC6]
Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.
Smirlis D., Duszenko M., Ruiz A.J., Scoulica E., Bastien P., Fasel N., Soteriadou K., 2010. Parasites and Vectors, 3 p. 107.
[URN][DOI][WoS][Pmid][serval:BIB_44B9C3A49489]
2008
 
An essential role for the Leishmania major metacaspase in cell cycle progression.
Ambit A., Fasel N., Coombs G.H., Mottram J.C., 2008. Cell Death and Differentiation, 15 (1) pp. 113-122. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_482A40DCFB1C]
 
The Leishmania Proteome
Fasel N., Acestor N., El Fadili-Kündig A., Gonzalez I., Masina S., 2008. pp. 55-74 dans Myler P.J., Fasel N. (eds.) Leishmania : after the genome chap. 4, Caister Academic Press.
[serval:BIB_682C6CB71A75]
 
The proteolytic activity of the paracaspase MALT1 is key in T cell activation
Rebeaud F., Hailfinger S., Posevitz-Fejfar A., Tapernoux M., Moser R., Rueda D., Gaide O., Guzzardi M., Iancu E. M., Rufer N. et al., 2008. Nature Immunology, 9 (3) pp. 272-281. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_68ADE902DD96]
2007
 
Histone H1 regulates chromatin condensation in Leishmania parasites.
Masina S., Zangger H., Rivier D., Fasel N., 2007. Experimental Parasitology, 116 (1) pp. 83-87.
[DOI][WoS][Pmid][serval:BIB_721FF45AC3A7]
Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis.
Moreno J., Nieto J., Masina S., Cañavate C., Cruz I., Chicharro C., Carrillo E., Napp S., Reymond C., Kaye P.M. et al., 2007. Vaccine, 25 (29) pp. 5290-5300.
[URN][DOI][WoS][Pmid][serval:BIB_6EA17DB53517]
 
Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity.
González I.J., Desponds C., Schaff C., Mottram J.C., Fasel N., 2007. International Journal for Parasitology, 37 (2) pp. 161-172.
[DOI][WoS][Pmid][serval:BIB_47B56F543DA7]
2006
 
Comparative protein profiling identifies elongation factor-1beta and tryparedoxin peroxidase as factors associated with metastasis in Leishmania guyanensis.
Walker J., Acestor N., Gongora R., Quadroni M., Segura I., Fasel N., Saravia N.G., 2006. Molecular and Biochemical Parasitology, 145 (2) pp. 254-264. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8B1C88A8B619]
Resistance to oxidative stress is associated with metastasis in mucocutaneous leishmaniasis.
Acestor N., Masina S., Ives A., Walker J., Saravia N.G., Fasel N., 2006. Journal of Infectious Diseases, 194 (8) pp. 1160-1167.
[URN][DOI][WoS][Pmid][serval:BIB_13078567BBE1]
2004
 
A recombinant rubella virus E1 glycoprotein as a rubella vaccine candidate.
Perrenoud G., Messerli F., Thierry A.C., Beltraminelli N., Cousin P., Fasel N., Vallet V., Demotz S., Duchosal M.A., Moulon C., 2004. Vaccine, 23 (4) pp. 480-488.
[DOI][WoS][Pmid][serval:BIB_AFA406FAAEB9]
 
Genomic organization and gene expression in a chromosomal region of Leishmania major.
Monnerat S., Martinez-Calvillo S., Worthey E., Myler P.J., Stuart K.D., Fasel N., 2004. Molecular and Biochemical Parasitology, 134 (2) pp. 233-243.
[DOI][WoS][Pmid][serval:BIB_5A58A742D42C]
 
Humoral and cellular immune responses against Type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population.
Nakhaee A., Taheri T., Taghikhani M., Mohebali M., Salmanian A.H., Fasel N., Rafati S., 2004. Veterinary Parasitology, 119 (2-3) pp. 107-123.
[DOI][WoS][Pmid][serval:BIB_5B8514AF5BB6]
 
Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis.
Rafati S., Salmanian A.H., Taheri T., Masina S., Schaff C., Taslimi Y., Fasel N., 2004. Molecular and Biochemical Parasitology, 135 (1) pp. 13-20.
[DOI][WoS][Pmid][serval:BIB_6B968DA46DB7]
2003
 
Enhanced sensitivity detection of protein immobilization by fluorescent interference on oxidized silicon.
Volle J.N., Chambon G., Sayah A., Reymond C., Fasel N., Gijs M.A., 2003. Biosensors and Bioelectronics, 19 (5) pp. 457-464.
[DOI][WoS][Pmid][serval:BIB_736547BDF053]
 
Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis.
Rafati S., Nakhaee A., Taheri T., Ghashghaii A., Salmanian A.H., Jimenez M., Mohebali M., Masina S., Fasel N., 2003. Experimental Parasitology, 103 (3-4) pp. 143-151.
[DOI][WoS][Pmid][serval:BIB_C3AD4F90D519]
 
Leishmania cysteine proteinases: from gene to subunit vaccine.
Rafati S., Fasel N., Masina S., 2003. Current Genomics, 4 (3) pp. 253-261. Peer-reviewed.
[DOI][serval:BIB_26473]
Life after death: are trypanosomatids programmed to die for the survival of their partners?
Fasel N., Masina M.S., 2003. Kinetoplastid Biology and Disease, 2 (1) p. 4.
[URN][DOI][Pmid][serval:BIB_CDD7940126FF]
 
Mapping the proteome of Leishmania Viannia parasites using two-dimensional polyacrylamide gel electrophoresis and associated technologies.
Góngora R., Acestor N., Quadroni M., Fasel N., Saravia N.G., Walker J., 2003. Biomédica, 23 (2) pp. 153-160.
[Pmid][serval:BIB_3F25E1FD8F6A]
Protection against cutaneous leishmaniasis in outbred vervet monkeys using a recombinant histone H1 antigen.
Masina S., Gicheru M.M., Demotz S.O., Fasel N.J., 2003. Journal of Infectious Diseases, 188 (8) pp. 1250-1257.
[URN][DOI][WoS][Pmid][serval:BIB_CAC86D46812C]
 
Sense and antisense transcripts in the histone H1 (HIS-1) locus of Leishmania major.
Belli S.I., Monnerat S., Schaff C., Masina S., Noll T., Myler P.J., Stuart K., Fasel N., 2003. International Journal for Parasitology, 33 (9) pp. 965-975.
[DOI][WoS][Pmid][serval:BIB_775E759B416E]
2002
 
Establishing two-dimensional gels for the analysis of Leishmania proteomes.
Acestor N., Masina S., Walker J., Saravia N.G., Fasel N., Quadroni M., 2002/07. Proteomics, 2 (7) pp. 877-879. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_33D358FBBC78]
 
Cell death in Leishmania induced by stress and differentiation: programmed cell death or necrosis?
Zangger H., Mottram J.C., Fasel N., 2002. Cell Death and Differentiation, 9 (10) pp. 1126-1139.
[DOI][WoS][Pmid][serval:BIB_B00EEE5ED777]
 
Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration.
Johnson-Léger C.A., Aurrand-Lions M., Beltraminelli N., Fasel N., Imhof B.A., 2002. Blood, 100 (7) pp. 2479-2486.
[DOI][WoS][Pmid][serval:BIB_3503717C64CA]
2001
 
A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major.
Rafati S., Salmanian A.H., Taheri T., Vafa M., Fasel N., 2001. Vaccine, 19 (25-26) pp. 3369-3375.
[DOI][WoS][Pmid][serval:BIB_184E809001B1]
 
Identification of Leishmania major cysteine proteinases as targets of the immune response in humans.
Rafati S., Salmanian A.H., Hashemi K., Schaff C., Belli S., Fasel N., 2001. Molecular and Biochemical Parasitology, 113 (1) pp. 35-43.
[DOI][WoS][Pmid][serval:BIB_5CAE97E74F6C]
 
Long synthetic peptides as biologically active proteins: the example of the chemokines.
Thierry A.C., Pinaud S., Bigler N., Perrenoud G., Denis B., Roggero M.A., Fasel N., Moulon C., Demotz S., 2001. Biologicals : Journal of the International Association of Biological Standardization, 29 (3-4) pp. 259-263.
[DOI][WoS][Pmid][serval:BIB_F8C31B6E07F2]
 
Native-like, long synthetic peptides as components of sub-unit vaccines: practical and theoretical considerations for their use in humans.
Demotz S., Moulon C., Roggero M.A., Fasel N., Masina S., 2001. Molecular Immunology, 38 (6) pp. 415-422.
[DOI][WoS][Pmid][serval:BIB_0A3FA4743FE0]
2000
 
Expression and one-step purification of Plasmodium proteins in dictyostelium.
van Bemmelen M.X., Beghdadi-Rais C., Desponds C., Vargas E., Herrera S., Reymond C.D., Fasel N., 2000. Molecular and Biochemical Parasitology, 111 (2) pp. 377-390.
[DOI][WoS][Pmid][serval:BIB_660D23EDC3B1]
1999
 
Leishmania major: histone H1 gene expression from the sw3 locus.
Belli S., Formenton A., Noll T., Ivens A., Jacquet R., Desponds C., Hofer D., Fasel N., 1999. Experimental Parasitology, 91 (2) pp. 151-160.
[DOI][WoS][Pmid][serval:BIB_DCC78D24A5DA]
 
The protective capacities of histone H1 against experimental murine cutaneous leishmaniasis.
Solioz N., Blum-Tirouvanziam U., Jacquet R., Rafati S., Corradin G., Mauël J., Fasel N., 1999. Vaccine, 18 (9-10) pp. 850-859.
[DOI][WoS][Pmid][serval:BIB_31AFF7AE0546]
1998
Purification of recombinant proteins by chemical removal of the affinity tag.
Rais-Beghdadi C., Roggero M.A., Fasel N., Reymond C.D., 1998. Applied Biochemistry and Biotechnology, 74 (2) pp. 95-103.
[URN][DOI][WoS][Pmid][serval:BIB_66D77565FEDE]
 
The Complete Chromosomal Organization of the Reference Strain of the Leishmania Genome Project, L. major ;Friedlin'.
Ravel C., Dubessay P., Bastien P., Blackwell J.M., Ivens A.C., The Leishmania Genome Network, 1998. Parasitology Today, 14 (8) pp. 301-303.
[DOI][WoS][Pmid][serval:BIB_365FB9BF4A3D]
1997
 
Histone H1 expression varies during the Leishmania major life cycle.
Noll T.M., Desponds C., Belli S.I., Glaser T.A., Fasel N.J., 1997. Molecular and Biochemical Parasitology, 84 (2) pp. 215-227.
[DOI][WoS][Pmid][serval:BIB_F08D44C51460]
1996
 
Cell surface expression of a functional rubella virus E1 glycoprotein by addition of a GPI anchor.
Bernasconi E., Fasel N., Wittek R., 1996/06. Journal of Cell Science, 109 (6) pp. 1195-1201.
[WoS][Pmid][serval:BIB_20CC54E3DFD4]
1995
 
Anchoring of an immunogenic Plasmodium falciparum circumsporozoite protein on the surface of Dictyostelium discoideum.
Reymond C.D., Beghdadi-Rais C., Roggero M., Duarte E.A., Desponds C., Bernard M., Groux D., Matile H., Bron C., Corradin G. et al., 1995. Journal of Biological Chemistry, 270 (21) pp. 12941-12947.
[DOI][WoS][Pmid][serval:BIB_345099EB55B9]
 
Fatty acids regulate Thy-1 antigen mRNA stability in T lymphocyte precursors.
Déglon N., Wilson A., Desponds C., Laurent P., Bron C., Fasel N., 1995. European Journal of Biochemistry, 231 (3) pp. 687-696.
[DOI][WoS][Pmid][serval:BIB_76CA8C1BCA75]
 
Localization of HLA-A2.1-restricted T cell epitopes in the circumsporozoite protein of Plasmodium falciparum.
Blum-Tirouvanziam U., Servis C., Habluetzel A., Valmori D., Men Y., Esposito F., Del Nero L., Holmes N., Fasel N., Corradin G., 1995. Journal of Immunology, 154 (8) pp. 3922-3931.
[WoS][Pmid][serval:BIB_AA72CA2FD058]
 
Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein.
Roggero M.A., Filippi B., Church P., Hoffman S.L., Blum-Tirouvanziam U., Lopez J.A., Esposito F., Matile H., Reymond C.D., Fasel N. et al., 1995. Molecular Immunology, 32 (17-18) pp. 1301-1309.
[DOI][WoS][Pmid][serval:BIB_DF6578240513]
 
The polymeric immunoglobulin receptor: signals for polarized expression.
Poulain-Godefroy O., Hirt R.P., Fasel N., Kraehenbühl J.P., 1995. Advances in Experimental Medicine and Biology, 371A pp. 217-220.
[WoS][Pmid][serval:BIB_515F30917C85]
1994
 
A trap system for the isolation of amino acid sequences inducing GPI anchor addition.
Fasel N., Stark H., Bron C., Beghdadi-Rais C., 1994. Brazilian Journal of Medical and Biological Research, 27 (2) pp. 189-193.
[WoS][Pmid][serval:BIB_64698EE58819]
 
Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides.
Blum-Tirouvanziam U., Beghdadi-Rais C., Roggero M.A., Valmori D., Bertholet S., Bron C., Fasel N., Corradin G., 1994. Journal of Immunology, 153 (9) pp. 4134-4141.
[WoS][Pmid][serval:BIB_C014428D5942]
 
Inducible protein expression using a glucocorticoid-sensitive vector.
Hirt R.P., Fasel N., Kraehenbuhl J.P., 1994. pp. 247-262 dans Protein Expression in Animal Cells, Elsevier.
[DOI][WoS][Pmid][serval:BIB_6ABB68D064A5]
 
Minimal membrane and secreted mu poly(A) signals specify developmentally-regulated immunoglobulin heavy chain mRNA ratios without RNA splicing.
Fasel N.J., Deglon N., Beghdadi-Rais C., Law R., Bron C., Wall R., 1994. Molecular Immunology, 31 (7) pp. 563-566.
[WoS][Pmid][serval:BIB_75B17CC01977]
1993
 
Carboxyl terminus structural requirements for glycosyl-phosphatidylinositol anchor addition to cell surface proteins.
Beghdadi-Rais C., Schreyer M., Rousseaux M., Borel P., Eisenberg R.J., Cohen G.H., Bron C., Fasel N., 1993. Journal of Cell Science, 105 (3) pp. 831-840.
[WoS][Pmid][serval:BIB_9771E1D4FCF4]
 
Identification of a histone H1-like gene expressed in Leishmania major.
Fasel N.J., Robyr D.C., Mauel J., Glaser T.A., 1993. Molecular and Biochemical Parasitology, 62 (2) pp. 321-323.
[DOI][WoS][Pmid][serval:BIB_2E1DC2CF8274]
 
Induction of macrophage nitric oxide production by interferon-gamma and tumor necrosis factor-alpha is enhanced by interleukin-10.
Corradin S.B., Fasel N., Buchmüller-Rouiller Y., Ransijn A., Smith J., Mauël J., 1993. European Journal of Immunology, 23 (8) pp. 2045-2048.
[DOI][WoS][Pmid][serval:BIB_A4D61B1FF36D]
1992
 
Dictyostelium discoideum as an expression host for the circumsporozoite protein of Plasmodium falciparum.
Fasel N., Begdadi-Rais C., Bernard M., Bron C., Corradin G., Reymond C.D., 1992. Gene, 111 (2) pp. 157-163.
[DOI][WoS][Pmid][serval:BIB_0645695131F1]
 
Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector.
Hirt R.P., Poulain-Godefroy O., Billotte J., Kraehenbuhl J.P., Fasel N., 1992. Gene, 111 (2) pp. 199-206.
[DOI][WoS][Pmid][serval:BIB_170BE82CCAAF]
 
Membrane mu poly(A) signal and 3' flanking sequences function as a transcription terminator for immunoglobulin-encoding genes.
Fasel N.J., Rousseaux M., Déglon N., Govan H.L., Law R., Bron C., Wall R., 1992. Gene, 122 (2) pp. 297-304.
[DOI][WoS][Pmid][serval:BIB_CBEB3630DA8A]
 
Multi-level regulation of Thy-1 antigen expression in mouse T lymphomas.
Fasel N.J., Déglon N., 1992. Immunogenetics, 35 (2) pp. 126-130.
[DOI][WoS][Pmid][serval:BIB_4BC1457C20AA]
1991
 
Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.
Fasel N., Déglon N., Rousseaux M., Beghdadi-Rais C., Bernard M., Bron C., 1991. Cell Biology International Reports, 15 (11) pp. 1051-1064.
[WoS][Pmid][serval:BIB_2BA8D14627DF]
 
Glycolipid-anchored membrane proteins
Bron C., Fasel N., 1991. Bulletin de l'Institut Pasteur, 89 (1) pp. 59-69. Peer-reviewed.
[WoS][serval:BIB_4F39372E6D11]
 
Isolation from mouse fibroblasts of a cDNA encoding a new form of the fibroblast growth factor receptor (flg).
Fasel N.J., Bernard M., Déglon N., Rousseaux M., Eisenberg R.J., Bron C., Cohen G.H., 1991. Biochemical and Biophysical Research Communications, 178 (1) pp. 8-15.
[DOI][WoS][Pmid][serval:BIB_6648739851BC]
 
Production and use of monoclonal IgA antibodies complexed with recombinant secretory component for passive mucosal protection.
Michetti P., Hirt R., Weltzin R., Fasel N., Schaerer E., Neutra M.R., Kraehenbühl J.P., 1991. Advances in Experimental Medicine and Biology, 310 pp. 183-185.
[Pmid][serval:BIB_848815F2C5B5]
 
Translocation of the yeast dolichol-phosphate-mannose synthase into microsomal membranes.
Déglon N., Krapp A., Bron C., Fasel N., 1991. Biochemical and Biophysical Research Communications, 174 (3) pp. 1337-1342.
[DOI][WoS][Pmid][serval:BIB_0C3D172F7AE0]
1990
 
Polarity of endogenous and exogenous glycosyl-phosphatidylinositol-anchored membrane proteins in Madin-Darby canine kidney cells.
Wilson J.M., Fasel N., Kraehenbuhl J.P., 1990. Journal of Cell Science, 96 (Pt 1) pp. 143-149.
[WoS][Pmid][serval:BIB_1D70632C0F16]
1989
 
In vitro attachment of glycosyl-inositolphospholipid anchor structures to mouse Thy-1 antigen and human decay-accelerating factor.
Fasel N., Rousseaux M., Schaerer E., Medof M.E., Tykocinski M.L., Bron C., 1989. Proceedings of the National Academy of Sciences of the United States of America, 86 (18) pp. 6858-6862.
[DOI][WoS][Pmid][serval:BIB_3A8094F6471B]
1987
 
Control of μ + ∂ gene expression in B lymphocyte development
Fasel N., Briskin M., Carter C., Govan H., Hermanson G., Law R., Wall R., 1987., University of South Florida College of Medicine International Symposium on Antibodies pp. 35-46 dans Szentivanyi A., Maurer P.H., Janicki B.W. (eds.) Antibodies: structure, synthesis, function, and immunologic intervention in disease, University of South Florida international biomedical symposia series, Plenum Press.
[serval:BIB_337D124DB690]
 
Protein-binding site at the immunoglobulin mu membrane polyadenylylation signal: possible role in transcription termination.
Law R., Kuwabara M.D., Briskin M., Fasel N., Hermanson G., Sigman D.S., Wall R., 1987. Proceedings of the National Academy of Sciences of the United States of America, 84 (24) pp. 9160-9164.
[DOI][WoS][Pmid][serval:BIB_22EE4F1C96BF]
 
T cell receptor beta chain gene rearrangements and V beta gene usage in horse cytochrome c-specific T cell hybridomas.
Baumhüter S., Fasel N., Corradin G., Guardiola J., 1987. European Journal of Immunology, 17 (5) pp. 657-661.
[DOI][WoS][Pmid][serval:BIB_91EBC3529248]
1986
 
A novel RNA in which the 5' end is generated by cleavage at the poly(A) site of immunoglobulin heavy-chain secreted mRNA.
Rogers J., Fasel N., Wall R., 1986. Molecular and cellular biology, 6 (12) pp. 4749-4752. Peer-reviewed.
[WoS][Pmid][serval:BIB_B1AE463C5390]
1985
 
A short segment of viral DNA is required for stimulation of transcription of mouse mammary tumor virus genes by glucocorticoid hormones
Diggelmann H, Buetti E., Owen D., Fasel N., Firzlaff J., Vessaz A.L., Pearson K., 1985. pp. 339-353 dans Becker Y. (eds.) Viral messenger RNA : transcription, processing, splicing and molecular structure, Martinus Nijhoff.
[serval:BIB_1AD689011D57]
1983
Nucleotide sequence of the 5' noncoding region and part of the gag gene of mouse mammary tumor virus; identification of the 5' splicing site for subgenomic mRNAs.
Fasel N., Buetti E., Firzlaff J., Pearson K., Diggelmann H., 1983. Nucleic Acids Research, 11 (20) pp. 6943-6955.
[URN][DOI][WoS][Pmid][serval:BIB_4C205CB3597F]
 
The expression of cloned MMTV DNA in transfected cells
Diggelmann H, Buetti E., Fasel N., Owen D., Vessaz A.L., 1983. pp. 303-315 dans Rich M.A., Hager J.C., Furmanski P. (eds.) Understanding breast cancer, Dekker.
[serval:BIB_E863E1B12E3E]
1982
 
Mouse mammary tumor virus : a model system for regulation of gene expression
Diggelmann H., Buetti E., Fasel N, Owen D., Vessaz A., Pearson K., 1982. Jahrbuch der Schweizerischen Naturforschenden Gesellschaft Wissenschaftlicher Teil = Annuaire de la Société Helvétique des Sciences Naturelles. Partie scientifique, 162 pp. 31-34.
[DOI][serval:BIB_79F45FEA4BC0]
 
The region of mouse mammary tumor virus DNA containing the long terminal repeat includes a long coding sequence and signals for hormonally regulated transcription.
Fasel N., Pearson K., Buetti E., Diggelmann H., 1982. EMBO Journal, 1 (1) pp. 3-7. Peer-reviewed.
[URN][WoS][Pmid][serval:BIB_52F8CF964FE1]
1980
 
Embryonic development of NMRI mice: relationship between the weight, age and ossification of embryos.
Fasel N., Schowing J., 1980. Laboratory animals, 14 (3) pp. 243-246. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3BF6AEC6E707]
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