Fabio Martinon

Publications | Mémoires et thèses

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94 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 |
2024
 
The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation.
Ehirchiou D., Bernabei I., Pandian V.D., Nasi S., Chobaz V., Castelblanco M., So A., Martinon F., Li X., Acha-Orbea H. et al., 2024/06/11. Arthritis research & therapy, 26 (1) p. 119. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3A78C4905CEE]
HSP90β controls NLRP3 autoactivation.
Spel L., Hou C., Theodoropoulou K., Zaffalon L., Wang Z., Bertoni A., Volpi S., Hofer M., Gattorno M., Martinon F., 2024/03. Science advances, 10 (9) pp. eadj6289. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D489F461335C]
2023
ER-trafficking triggers NRF1 ubiquitination to promote its proteolytic activation.
Chavarria C., Zaffalon L., Ribeiro S.T., Op M., Quadroni M., Iatrou M.S., Chapuis C., Martinon F., 2023/10/20. iScience, 26 (10) p. 107777. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_85F1CAE98072]
NLRP3 leucine-rich repeats control induced and spontaneous inflammasome activation in cryopyrin-associated periodic syndrome.
Theodoropoulou K., Spel L., Zaffalon L., Delacrétaz M., Hofer M., Martinon F., 2023/01. The Journal of allergy and clinical immunology, 151 (1) pp. 222-232.e9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17138F05CB5E]
2022
CDC42 regulates PYRIN inflammasome assembly.
Spel L., Zaffalon L., Hou C., Nganko N., Chapuis C., Martinon F., 2022/11/15. Cell reports, 41 (7) p. 111636. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8264D9307A8A]
The protease DDI2 regulates NRF1 activation in response to cadmium toxicity.
Ribeiro S.T., de Gassart A., Bettigole S., Zaffalon L., Chavarria C., Op M., Nugraha K., Martinon F., 2022/10/21. iScience, 25 (10) p. 105227. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F504A8AA7323]
The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma.
Op M., Ribeiro S.T., Chavarria C., De Gassart A., Zaffalon L., Martinon F., 2022/05/19. Cell death & disease, 13 (5) p. 475. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A9FBE08A94DB]
2021
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G., Tsai C.H., Gallart-Ayala H., Yu Y.R., Franco F., Zaffalon L., Xie X., Li X., Xiao Z., Raines L.N. et al., 2021/11. Nature immunology, 22 (11) pp. 1403-1415. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_38FF542D6B24]
Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING.
Bruand M., Barras D., Mina M., Ghisoni E., Morotti M., Lanitis E., Fahr N., Desbuisson M., Grimm A., Zhang H. et al., 2021/07/20. Cell reports, 36 (3) p. 109412. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_745449157CA6]
Detection of viruses by inflammasomes.
Spel L., Martinon F., 2021/02. Current opinion in virology, 46 pp. 59-64. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_72676FF55EC7]
2020
Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis.
Jarosz-Griffiths H.H., Scambler T., Wong C.H., Lara-Reyna S., Holbrook J., Martinon F., Savic S., Whitaker P., Etherington C., Spoletini G. et al., 2020/03/02. eLife, 9 pp. e54556. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E0016C3B6120]
Inflammasomes contributing to inflammation in arthritis.
Spel L., Martinon F., 2020/03. Immunological reviews, 294 (1) pp. 48-62. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DE14124731A8]
2019
ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis.
Scambler T., Jarosz-Griffiths H.H., Lara-Reyna S., Pathak S., Wong C., Holbrook J., Martinon F., Savic S., Peckham D., McDermott M.F., 2019/09/18. eLife, 8. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_106C52DF162A]
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.
Lara-Reyna S., Scambler T., Holbrook J., Wong C., Jarosz-Griffiths H.H., Martinon F., Savic S., Peckham D., McDermott M.F., 2019. Frontiers in immunology, 10 p. 1789. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_68FA118EDC28]
2018
 
Gasdermin D opens the way for NETs.
Spel L., Martinon F., 2018/12. Nature reviews. Rheumatology, 14 (12) pp. 690-692. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1E30AF593244]
A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate.
Jamilloux Y., Lagrange B., Di Micco A., Bourdonnay E., Provost A., Tallant R., Henry T., Martinon F., 2018/08/10. The Journal of biological chemistry, 293 (32) pp. 12563-12575. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9D6C34A7651F]
Inflammation initiated by stressed organelles.
Martinon F., 2018/07. Joint, bone, spine, 85 (4) pp. 423-428. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_18E9EB64E09E]
 
Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation.
Castelblanco M., Lugrin J., Ehirchiou D., Nasi S., Ishii I., So A., Martinon F., Busso N., 2018/02/16. The Journal of biological chemistry, 293 (7) pp. 2546-2557. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_61000D21C5FD]
The AIM2 inflammasome: Sensor of pathogens and cellular perturbations.
Lugrin J., Martinon F., 2018/01. Immunological reviews, 281 (1) pp. 99-114. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0AE0392EBD49]
2017
Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth.
Bujisic B., De Gassart A., Tallant R., Demaria O., Zaffalon L., Chelbi S., Gilliet M., Bertoni F., Martinon F., 2017/04/27. Blood, 129 (17) pp. 2420-2428. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AC6D5644ABF2]
 
IRE1 gives weight to obesity-associated inflammation.
Bujisic B., Martinon F., 2017/04/18. Nature immunology, 18 (5) pp. 479-480. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C4E37AD3DCD4]
Translating the anticancer properties of eEF2K.
De Gassart A., Martinon F., 2017/02/16. Cell cycle, 16 (4) pp. 299-300. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D4C7CFCABC1C]
 
Detection of ASC Oligomerization by Western Blotting.
Lugrin J., Martinon F., 2017. Bio-Protocol, 7 (10) pp. NA. Peer-reviewed.
[DOI][Pmid][serval:BIB_93717B76B904]
Inflammation in gout: mechanisms and therapeutic targets.
So A.K., Martinon F., 2017. Nature Reviews. Rheumatology, 13 (11) pp. 639-647. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F8C4ACBA5649]
 
Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome.
Cheung M.S., Theodoropoulou K., Lugrin J., Martinon F., Busso N., Hofer M., 2017. Journal of Immunology, 198 (5) pp. 2063-2069. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BDA5612B871D]
2016
Pharmacological eEF2K activation promotes cell death and inhibits cancer progression.
De Gassart A., Demaria O., Panes R., Zaffalon L., Ryazanov A.G., Gilliet M., Martinon F., 2016/10. EMBO reports, 17 (10) pp. 1471-1484. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1DC620721907]
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A., Frera G., Lugrin J., Jamilloux Y., Hsu E.T., Tardivel A., De Gassart A., Zaffalon L., Bujisic B., Siegert S. et al., 2016/08/09. Proceedings of the National Academy of Sciences of the United States of America, 113 (32) pp. E4671-80. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_29BEBCA2CFB2]
Raptor hunted by caspases.
Martin R., Thome M., Martinon F., Fasel N., 2016/06/02. Cell death & disease, 7 (6) pp. e2242. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F08DA0F683EB]
An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.
De Gassart A., Bujisic B., Zaffalon L., Decosterd L.A., Di Micco A., Frera G., Tallant R., Martinon F., 2016. Proceedings of the National Academy of Sciences of the United States of America, 113 (2) pp. E117-E126.
[URN][DOI][WoS][Pmid][serval:BIB_C26C4352CC95]
 
Cell-Free Assay for Inflammasome Activation.
Jamilloux Y., Martinon F., 2016. Methods in molecular biology, 1417 pp. 207-215. Peer-reviewed.
[DOI][Pmid][serval:BIB_2191EA9C70BB]
2015
 
New players driving inflammation in monogenic autoinflammatory diseases.
Martinon F., Aksentijevich I., 2015. Nature Reviews. Rheumatology, 11 (1) pp. 11-20. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4011C7574B1B]
 
Pathogenesis of adult-onset Still's disease: new insights from the juvenile counterpart.
Jamilloux Y., Gerfaud-Valentin M., Martinon F., Belot A., Henry T., Sève P., 2015. Immunologic Research, 61 (1-2) pp. 53-62.
[DOI][WoS][Pmid][serval:BIB_DAFB009FA0BE]
 
Pyroptosis: Caspase-11 Unlocks the Gates of Death.
de Gassart A., Martinon F., 2015. Immunity, 43 (5) pp. 835-837.
[DOI][WoS][Pmid][serval:BIB_6E958EED3865]
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Demaria O., De Gassart A., Coso S., Gestermann N., Di Domizio J., Flatz L., Gaide O., Michielin O., Hwu P., Petrova T.V. et al., 2015. Proceedings of the National Academy of Sciences of the United States of America, 112 (50) pp. 15408-15413.
[URN][DOI][WoS][Pmid][serval:BIB_572BDFE9D6A6]
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.
Ives A., Nomura J., Martinon F., Roger T., LeRoy D., Miner J.N., Simon G., Busso N., So A., 2015. Nature Communications, 6 p. 6555.
[URN][DOI][WoS][Pmid][serval:BIB_2EC23A4A7881]
2014
 
L'inflammation
Martinon F., 2014. pp. 175-181 dans Cramer P. (eds.) Le défi des maladies infectieuses, Docis.
[serval:BIB_B40382408DAE]
2013
 
Crystal structure of NLRC4 reveals its autoinhibition mechanism.
Hu Z., Yan C., Liu P., Huang Z., Ma R., Zhang C., Wang R., Zhang Y., Martinon F., Miao D. et al., 2013. Science, 341 (6142) pp. 172-175. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5894A71A692A]
 
Did cholera toxin finally get caught?
Martinon F., van der Goot F.G., 2013. Cell Host and Microbe, 13 (5) pp. 501-503.
[DOI][WoS][Pmid][serval:BIB_8B879238588E]
2012
 
Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome.
Martinon F., 2012. Immunity, 36 (3) pp. 313-315.
[DOI][WoS][Pmid][serval:BIB_38FBB482D658]
 
Targeting endoplasmic reticulum signaling pathways in cancer.
Martinon F., 2012. Acta Oncologica, 51 (7) pp. 822-830.
[DOI][WoS][Pmid][serval:BIB_CC94D4E9246F]
The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.
Martinon F., 2012. Microbes and Infection, 14 (14) pp. 1293-1300.
[URN][DOI][WoS][Pmid][serval:BIB_A6EFFA30B665]
2011
 
Innate immunity
Glimcher L.H., Martinon F., Modlin R.L., 2011. Current Opinion in Immunology, 23 (1) pp. 1-2.
[DOI][WoS][Pmid][serval:BIB_CF90D0F29403]
 
Molecular definition of inflammasomes
Pétrilli V., Martinon F., 2011. pp. 1-16 dans Couillin I., Pétrilli V., Martinon F. (eds.) The inflammasomes, Springer.
[DOI][serval:BIB_21D97121A13C]
Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum.
Martinon F., Glimcher L.H., 2011. Current Opinion in Immunology, 23 (1) pp. 35-40. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FAD1260D144C]
 
The inflammasomes
Couillin I., Pétrilli V., Martinon F. (eds.), 2011. Progress in Inflammation Research 224, Springer.
[DOI][serval:BIB_409BD15E067B]
 
The unfolded protein response: integrating stress signals through the stress sensor IRE1α.
Hetz C., Martinon F., Rodriguez D., Glimcher L.H., 2011. Physiological Reviews, 91 (4) pp. 1219-1243.
[DOI][WoS][Pmid][serval:BIB_979BF5228E3F]
2010
 
Mechanisms of uric acid crystal-mediated autoinflammation.
Martinon F., 2010. Immunological Reviews, 233 (1) pp. 218-232.
[DOI][WoS][Pmid][serval:BIB_AA98E86CD2F3]
 
Signaling by ROS drives inflammasome activation.
Martinon F., 2010. European Journal of Immunology, 40 (3) pp. 616-619.
[DOI][WoS][Pmid][serval:BIB_1463B2B8CF67]
 
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.
Martinon F., Chen X., Lee A.H., Glimcher L.H., 2010. Nature Immunology, 11 (5) pp. 411-418.
[DOI][WoS][Pmid][serval:BIB_299B5C2A028A]
 
Update on biology: uric acid and the activation of immune and inflammatory cells.
Martinon F., 2010. Current Rheumatology Reports, 12 (2) pp. 135-141.
[DOI][Pmid][serval:BIB_9B1431934F6D]
2009
 
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha.
Lisbona F., Rojas-Rivera D., Thielen P., Zamorano S., Todd D., Martinon F., Glavic A., Kress C., Lin J.H., Walter P. et al., 2009. Molecular Cell, 33 (6) pp. 679-691.
[DOI][WoS][Pmid][serval:BIB_B63C0573C930]
 
The inflammasomes: guardians of the body.
Martinon F., Mayor A., Tschopp J., 2009. Annual Review of Immunology, 27 pp. 229-265. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_867211B86868]
2008
 
Detection of immune danger signals by NALP3.
Martinon F., 2008. Journal of Leukocyte Biology, 83 (3) pp. 507-511.
[DOI][WoS][Pmid][serval:BIB_8B6362D8B067]
 
Linking inflammasome activation and phagosome maturation.
Lazarevic V., Martinon F., 2008. Cell Host and Microbe, 3 (4) pp. 199-200.
[DOI][WoS][Pmid][serval:BIB_7A2FB72C2BDC]
2007
 
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses.
Mayor A., Martinon F., De Smedt T., Pétrilli V., Tschopp J., 2007. Nature Immunology, 8 (5) pp. 497-503.
[DOI][WoS][Pmid][serval:BIB_F48656689CBF]
 
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity.
Watanabe H., Gaide O., Pétrilli V., Martinon F., Contassot E., Roques S., Kummer J.A., Tschopp J., French L.E., 2007. Journal of Investigative Dermatology, 127 (8) pp. 1956-1963.
[DOI][WoS][Pmid][serval:BIB_1AFD20F9FC00]
 
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.
Pétrilli V., Papin S., Dostert C., Mayor A., Martinon F., Tschopp J., 2007. Cell Death and Differentiation, 14 (9) pp. 1583-1589.
[DOI][WoS][Pmid][serval:BIB_D1658F6AAE62]
 
Cells with defective p53-p21-pRb pathway are susceptible to apoptosis induced by p84N5 via caspase-6.
Garner E., Martinon F., Tschopp J., Beard P., Raj K., 2007. Cancer Research, 67 (16) pp. 7631-7637.
[DOI][WoS][Pmid][serval:BIB_F2437B28EA11]
 
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response.
Kummer J.A., Broekhuizen R., Everett H., Agostini L., Kuijk L., Martinon F., van Bruggen R., Tschopp J., 2007. Journal of Histochemistry and Cytochemistry, 55 (5) pp. 443-452.
[DOI][WoS][Pmid][serval:BIB_6B6909929545]
 
Inflammatory caspases and inflammasomes: master switches of inflammation.
Martinon F., Tschopp J., 2007. Cell Death and Differentiation, 14 (1) pp. 10-22.
[DOI][WoS][Pmid][serval:BIB_4BAF54017B93]
 
NALP inflammasomes: a central role in innate immunity.
Martinon F., Gaide O., Pétrilli V., Mayor A., Tschopp J., 2007. Seminars in Immunopathology, 29 (3) pp. 213-229.
[DOI][WoS][Pmid][serval:BIB_F735595367FC]
 
Orchestration of pathogen recognition by inflammasome diversity: Variations on a common theme.
Martinon F., 2007. European Journal of Immunology, 37 (11) pp. 3003-3006.
[DOI][WoS][Pmid][serval:BIB_2A352905650B]
 
The inflammasome, autoinflammatory diseases, and gout.
Pétrilli V., Martinon F., 2007. Joint, Bone, Spine, 74 (6) pp. 571-576.
[DOI][WoS][Pmid][serval:BIB_7103D8F3D957]
 
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing.
Papin S., Cuenin S., Agostini L., Martinon F., Werner S., Beer H.D., Grütter C., Grütter M., Tschopp J., 2007. Cell Death and Differentiation, 14 (8) pp. 1457-1466.
[DOI][WoS][Pmid][serval:BIB_24E61CE732DE]
2006
 
Intracellular trafficking of interleukin-1 receptor I requires Tollip.
Brissoni B., Agostini L., Kropf M., Martinon F., Swoboda V., Lippens S., Everett H., Aebi N., Janssens S., Meylan E. et al., 2006/11/21. Current biology, 16 (22) pp. 2265-2270. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F91D88EA2918]
 
Gout-associated uric acid crystals activate the NALP3 inflammasome.
Martinon F., Pétrilli V., Mayor A., Tardivel A., Tschopp J., 2006. Nature, 440 (7081) pp. 237-241.
[DOI][WoS][Pmid][serval:BIB_77EB618FD22F]
 
Gout: new insights into an old disease.
Martinon F., Glimcher L.H., 2006. Journal of Clinical Investigation, 116 (8) pp. 2073-2075.
[DOI][WoS][Pmid][serval:BIB_A285918E78E3]
 
Mycobacterium tuberculosis subverts innate immunity to evade specific effectors.
Loeuillet C., Martinon F., Perez C., Munoz M., Thome M., Meylan P.R., 2006. Journal of Immunology, 177 (9) pp. 6245-6255.
[WoS][Pmid][serval:BIB_EF9D927AC4DD]
2005
 
NLRs join TLRs as innate sensors of pathogens.
Martinon F., Tschopp J., 2005. Trends in Immunology, 26 (8) pp. 447-454.
[DOI][WoS][Pmid][serval:BIB_AEC9EA302701]
2004
 
Inflammatory diseases: is ubiquitinated NEMO at the hub?
Burns K.A., Martinon F., 2004/12/29. Current biology, 14 (24) pp. R1040-2. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A845825978C2]
 
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.
Martinon F., Agostini L., Meylan E., Tschopp J., 2004/11/09. Current biology, 14 (21) pp. 1929-1934. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F144620AF94D]
 
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases.
Martinon F., Tschopp J., 2004. Cell, 117 (5) pp. 561-574.
[DOI][WoS][Pmid][serval:BIB_510A7DBBFECF]
 
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Agostini L., Martinon F., Burns K., McDermott M.F., Hawkins P.N., Tschopp J., 2004. Immunity, 20 (3) pp. 319-325.
[DOI][WoS][Pmid][serval:BIB_36A1C5DE1F50]
 
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.
Meylan E., Burns K., Hofmann K., Blancheteau V., Martinon F., Kelliher M., Tschopp J., 2004. Nature Immunology, 5 (5) pp. 503-507.
[DOI][WoS][Pmid][serval:BIB_597ECAB38FE4]
2003
 
NALPs: a novel protein family involved in inflammation.
Tschopp J., Martinon F., Burns K., 2003. Nature Reviews. Molecular Cell Biology, 4 (2) pp. 95-104.
[DOI][WoS][Pmid][serval:BIB_2AC9B00E5AC4]
 
New insights into the mechanism of IL-1beta maturation.
Burns K., Martinon F., Tschopp J., 2003. Current Opinion in Immunology, 15 (1) pp. 26-30.
[DOI][WoS][Pmid][serval:BIB_5DF78B80BEEE]
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
Holler N., Tardivel A., Kovacsovics-Bankowski M., Hertig S., Gaide O., Martinon F., Tinel A., Deperthes D., Calderara S., Schulthess T. et al., 2003. Molecular and Cellular Biology, 23 (4) pp. 1428-1440.
[URN][DOI][WoS][Pmid][serval:BIB_36A07DDFD402]
2002
 
Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation.
Kovacsovics M., Martinon F., Micheau O., Bodmer J.L., Hofmann K., Tschopp J., 2002/05/14. Current biology, 12 (10) pp. 838-843. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CE1131445D35]
 
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis.
Aganna E., Martinon F., Hawkins P.N., Ross J.B., Swan D.C., Booth D.R., Lachmann H.J., Bybee A., Gaudet R., Woo P. et al., 2002. Arthritis and Rheumatism, 46 (9) pp. 2445-2452.
[DOI][WoS][Pmid][serval:BIB_179F75372E7A]
 
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-kappa B and is processed during apoptosis.
Meylan E., Martinon F., Thome M., Gschwendt M., Tschopp J., 2002. EMBO Reports, 3 (12) pp. 1201-1208.
[DOI][WoS][Pmid][serval:BIB_BB6B87F0CE62]
 
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Martinon F., Burns K., Tschopp J., 2002. Molecular Cell, 10 (2) pp. 417-426.
[DOI][WoS][Pmid][serval:BIB_026D9182BA59]
2001
 
The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation.
Martinon F., Hofmann K., Tschopp J., 2001/02/20. Current biology, 11 (4) pp. R118-20. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3A5E24C2A57D]
 
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension.
Kataoka T., Holler N., Micheau O., Martinon F., Tinel A., Hofmann K., Tschopp J., 2001. Journal of Biological Chemistry, 276 (22) pp. 19548-19554.
[DOI][WoS][Pmid][serval:BIB_E3B37A307C3F]
 
Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation.
Gaide O., Martinon F., Micheau O., Bonnet D., Thome M., Tschopp J., 2001. FEBS Letters, 496 (2-3) pp. 121-127.
[DOI][WoS][Pmid][serval:BIB_8AF1F1467937]
Equine herpesvirus protein E10 induces membrane recruitment and phosphorylation of its cellular homologue, bcl-10.
Thome M., Gaide O., Micheau O., Martinon F., Bonnet D., Gonzalez M., Tschopp J., 2001. Journal of Cell Biology, 152 (5) pp. 1115-1122.
[URN][DOI][WoS][Pmid][serval:BIB_800EE5019494]
 
Three adenovirus E3 proteins cooperate to evade apoptosis by tumor necrosis factor-related apoptosis-inducing ligand receptor-1 and -2.
Benedict C.A., Norris P.S., Prigozy T.I., Bodmer J.L., Mahr J.A., Garnett C.T., Martinon F., Tschopp J., Gooding L.R., Ware C.F., 2001. Journal of Biological Chemistry, 276 (5) pp. 3270-3278.
[DOI][WoS][Pmid][serval:BIB_B17DD93186C7]
2000
 
Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP
Martinon F., Holler N., Richard C., Tschopp J., 2000/02. FEBS Letters, 468 (2-3) pp. 134-6.
[DOI][WoS][Pmid][serval:BIB_277D6C76432F]
 
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways.
Kataoka T., Budd R.C., Holler N., Thome M., Martinon F., Irmler M., Burns K., Hahne M., Kennedy N., Kovacsovics M. et al., 2000. Current Biology, 10 (11) pp. 640-648. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F3D9BDE62A23]
 
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.
Burns K., Clatworthy J., Martin L., Martinon F., Plumpton C., Maschera B., Lewis A., Ray K., Tschopp J., Volpe F., 2000. Nature Cell Biology, 2 (6) pp. 346-351.
[DOI][WoS][Pmid][serval:BIB_5BDCD149CA30]
1999
 
Apoptosis: Silencing the death receptors.
Tschopp J., Martinon F., Hofmann K., 1999/05/20. Current biology, 9 (10) pp. R381-4. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_454CDB20B04A]
 
Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway.
Penna D., Müller S., Martinon F., Demotz S., Iwashima M., Valitutti S., 1999. Journal of Immunology, 163 (1) pp. 50-56.
[WoS][Pmid][serval:BIB_65FC75322886]
Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase.
Thome M., Martinon F., Hofmann K., Rubio V., Steiner V., Schneider P., Mattmann C., Tschopp J., 1999. Journal of Biological Chemistry, 274 (15) pp. 9962-9968.
[URN][DOI][WoS][Pmid][serval:BIB_4257D9EF40E8]
1998
 
Identification of CARDIAK, a RIP-like kinase that associates with caspase-1.
Thome M., Hofmann K., Burns K., Martinon F., Bodmer J.L., Mattmann C., Tschopp J., 1998. Current Biology, 8 (15) pp. 885-888.
[DOI][WoS][Pmid][serval:BIB_41D9A6840882]
MyD88, an adapter protein involved in interleukin-1 signaling.
Burns K., Martinon F., Esslinger C., Pahl H., Schneider P., Bodmer J.L., Di Marco F., French L., Tschopp J., 1998. Journal of Biological Chemistry, 273 (20) pp. 12203-12209.
[URN][DOI][WoS][Pmid][serval:BIB_5FF43594B66A]
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