Raphaël Roduit

Publications | Mémoires et thèses

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58 publications

2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1994 |
2021
CNGB3 Missense Variant Causes Recessive Achromatopsia in Original Braunvieh Cattle.
Häfliger I.M., Marchionatti E., Stengård M., Wolf-Hofstetter S., Paris J.M., Jacinto JGP, Watté C., Voelter K., Occelli L.M., Komáromy A.M. et al., 2021/11/18. International journal of molecular sciences, 22 (22) p. 12440. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B10B7C6B7425]
GSH-Independent Induction of ER Stress during Hypoglycaemia in the Retinal Cells of Mice
Fresia Daria, Cannizzaro Enrica, Borgo Angelica, Roduit Raphaël, 2021/06/07. Journal of Clinical Medicine, 10 (11) p. 2529.
[URN][DOI][WoS][Pmid][serval:BIB_FC8785D6DC79]
2020
Molecular Biomarkers of Neovascular Age-Related Macular Degeneration With Incomplete Response to Anti-Vascular Endothelial Growth Factor Treatment.
Mantel I., Borgo A., Guidotti J., Forestier E., Kirsch O., Derradji Y., Waridel P., Burdet F., Mehl F., Schweizer C. et al., 2020. Frontiers in pharmacology, 11 p. 594087. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_548B1E9F5D9F]
2019
 
Role of ER stress in hypoglycemia-induced mouse retina cell death
Daria Fresia, Cannizzaro Enrica, Borgo Angelica, Roduit Raphael (eds.), 2019/09/16., EASD meeting 2019, Barcelona, Spain.
[URN][serval:BIB_19A84CA6FB91]
 
Role of ER stress in hypoglycemia-induced mouse retina cell death.
Roduit Raphael (eds.), 2019/05/16., EASDec Meeting 2019, Amsterdam, Holland.
[serval:BIB_1ED80AC0BD49]
2018
 
Role of ER stress in hypoglycemia-induced mouse retina cell death
Fresia Daria, Cannizzaro Enrica, Roduit Raphael (eds.), 2018/09/03., RD meeting 2018, Killarney, Irlande.
[serval:BIB_C405EF6C077B]
2017
Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.
Pyakurel A., Balmer D., Saba-El-Leil M.K., Kizilyaprak C., Daraspe J., Humbel B.M., Voisin L., Le Y.Z., von Lintig J., Meloche S. et al., 2017/12/15. Molecular and cellular biology, 37 (24) pp. e00295-17. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_A339F680887A]
Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis.
Balmer D., Bapst-Wicht L., Pyakurel A., Emery M., Nanchen N., Bochet C.G., Roduit R., 2017. Frontiers in aging neuroscience, 9 p. 43. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F834CBD92641]
2016
Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina.
Emery M., Nanchen N., Preitner F., Ibberson M., Roduit R., 2016. Plos One, 11 (2) pp. e0150266. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_147AACF8356C]
2015
 
Biological Characterization of Gene Response to Insulin-induced Hypoglycemia in Mouse Retina
Emery Martine, Ibberson Mark, Preitner Frederic, Thorens Bernard, Schorderet Daniel, Roduit Raphael (eds.), 2015., American Diabetes Association, Boston.
[serval:BIB_768EDE5A768D]
2014
 
A2E induce a decrease of ERK1 /2 phosphorylation possibly via bFGF autocrine effect
Balmer D., Wicht L., Emery M., Schorderet D.F., Roduit R., 2014/07., 16th Internation Symposium on Retinal Degeneration RD 2014 dans A2E induce a decrease of ERK1 /2 phosphorylation possibly via bFGF autocrine effect. Peer-reviewed.
[serval:BIB_6C06C07B2434]
 
Complement Factor B Polymorphism and the Phenotype of Early Age-related Macular Degeneration.
Mantel I., Ambresin A., Moetteli L., Droz I., Roduit R., Munier F.L., Schorderet D.F., 2014. Ophthalmic Genetics, 35 (1) pp. 12-17. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_51AA14B02CD8]
 
Hypoglycemia and Retinal Cell Death
Roduit R., Balmer D., Ibberson M., Schorderet D.F., 2014. 10, Victor R. Preedy, Elsevier.
[DOI][serval:BIB_5D24A31AB6C1]
2013
 
Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells
Roduit R., Balmer D., Emery M., Andreux P., Auwerx J., Ginet V., Puyal J., Schorderet D.F., 2013/09., ISOCB Ocular Cell Biology Conference dans Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells. Peer-reviewed.
[WoS][Pmid][serval:BIB_9507DD6209D1]
Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells.
Balmer D., Emery M., Andreux P., Auwerx J., Ginet V., Puyal J., Schorderet D.F., Roduit R., 2013. PLoS One, 8 (9) pp. e74162. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9AAD44EE651C]
 
ERK1/2 pathway is activated in degenerated Rpe65-deficient mice.
Métrailler S., Emery M., Schorderet D.F., Cottet S., Roduit R., 2013. Experimental Eye Research, 116C pp. 86-95. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6FC1C3C8157A]
2012
 
Deciphering the effects of the bisretinoid A2E on mitogen-activated protein kinse in the retinal pigmented epithelium
Wicht Linda, Emery Martine, Schorderet Daniel, Roduit Raphael (eds.), 2012., XVth International Symposium on Retinal Degeneration.
[serval:BIB_5856544E63AF]
2011
Acute hypoglycemia induces retinal cell death in mouse.
Emery M., Schorderet D.F., Roduit R., 2011. Plos One, 6 (6) pp. e21586. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A2CBBC46E7C4]
 
Deciphering the effects of the bisretinoid A2E on mitogen-activated protein kinase on the retinal pigmented epithelium
Wicht Linda, Emery Martine, Schorderet Daniel, Roduit Raphael (eds.), 2011., 8th Lemanic Neuroscience Annual Meeting.
[serval:BIB_8E42AA171D6B]
2010
 
Acute hypoglycemia induces retinal cells death in mouse
Emery M., Agosti C., Schorderet D.F., Roduit R., 2010/07., 14th International Symposium on Retinal Degeneration dans Acute hypoglycemia induces retinal cells death in mouse. Peer-reviewed.
[WoS][Pmid][serval:BIB_6844AC6E5092]
 
Transcriptional Activation and Receptor Dimerization is Affected by Mutations in the NR2E3 Ligand-Binding Domain
Escher P., Von Alpen D., Voirol N., Favez T., Roduit R., Schorderet D., 2010., ARVO E-Abstrat 4077/A504 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
[serval:BIB_203A69696733]
2009
 
Glucose represses PPARα gene expression via AMP-activated protein kinase but not via p38 mitogen-activated protein kinase in the pancreatic β-cell.
Joly E., Roduit R., Peyot M.L., Habinowski S.A., Ruderman N.B., Witters L.A., Prentki M., 2009/12. Journal of diabetes, 1 (4) pp. 263-272. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_802A55897AFA]
 
Functional analysis of disease-causing NR2E3 mutations
Escher P., Voirol N., Favez T., Roduit R., Schorderet D.F., 2009., ARVO E-Abstract 2296 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
[serval:BIB_53B4AD4865BD]
Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family.
Escher P., Gouras P., Roduit R., Tiab L., Bolay S., Delarive T., Chen S., Tsai C.C., Hayashi M., Zernant J. et al., 2009. Human Mutation, 30 (3) pp. 342-351. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_07CD9A3E0C0E]
Mutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRX.
Roduit R., Escher P., Schorderet D.F., 2009. PloS one, 4 (10) pp. e7379. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B57E2853EAE3]
 
Rpe65 microarrays, from genes to phosphorylated proteins
Bolay S., Roduit R., Cottet S., Schorderet D.F., 2009., ARVO E-Abstract 1930 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
[serval:BIB_9A4A70496D76]
 
The DNA-binding domain (DBD) is essential for NR2E3 dimerization and interaction with Crx
Roduit R., Escher P., Emery M., Voirol N., Favez T., Schorderet D.F., 2009., ARVO E-Abstract 5459 dans Investigative ophthalmology and visual science. Peer-reviewed.
[serval:BIB_DA7E20779EE6]
2008
 
DNA-binding domain (DBD) is essential for NR2E3 dimerization and Crx interaction
Roduit R., Escher P., Emery M., Voirol N., Schorderet D.F., 2008/09., International Society for Ocular Cell Biology (ISOCB) dans DNA-binding domain (DBD) is essential for NR2E3 dimerization and Crx interaction. Peer-reviewed.
[WoS][Pmid][serval:BIB_42495CED7524]
 
Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases.
Maedler K., Schulthess F.T., Bielman C., Berney T., Bonny C., Prentki M., Donath M.Y., Roduit R., 2008. FASEB Journal, 22 (6) pp. 1905-1913. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2D2F8F842C76]
 
Ischémies et atteintes neuronales - apoptose
Roduit R., Schorderet D., 2008. pp. 184-194 dans Pournaras C.J. (eds.) Pathologies vasculaires oculaires, Masson.
[serval:BIB_2674B92A0A84]
MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells.
Roduit R., Schorderet D.F., 2008. Apoptosis, 13 (3) pp. 343-353. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1FF6934DDA79]
 
Modulation de l'apoptose à l'aide de peptides intracellulaires
Allaman-Pillet N., Roduit R., Produit-Zengaffinen N., Schorderet D.F., 2008. pp. 793-796 dans Pournaras C.J. (eds.) Pathologies vasculaires oculaires, Masson.
[serval:BIB_7237C8F9527B]
2007
 
Role of MAP kinase pathways in UV-induced retinal pigment epithelium apoptosis
Roduit R., Emery M., Despond A., Schorderet D.F., 2007/11., Neurosciences, Changins 11/07 dans Role of MAP kinase pathways in UV-induced retinal pigment epithelium apoptosis.
[serval:BIB_4A7FFCAFF46B]
 
Atrophins are corepressors for NR2E3
Escher P., Roduit R., Favez T., Voirol N., Chen S., Tsai C.C., Schorderet D.F., 2007/05., ARVO Annual Meeting 2007 dans Atrophins are corepressors for NR2E3. Peer-reviewed, Investigate ophtalmology and visual science IOVS.
[serval:BIB_558F89CF88AA]
2006
 
Homogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates
Guenat S., Rouleau N., Bielmann C., Bedard J., Maurer F., Allaman-Pillet N., Nicod P., Bielefeld-Sevigny M., Beckmann J. S., Bonny C. et al., 2006/12. Journal of Biomolecular Screening, 11 (8) pp. 1015-26. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_95855612ABCB]
 
A unique set of SH3-SH3 interactions controls IB1 homodimerization.
Kristensen O., Guenat S., Dar I., Allaman-Pillet N., Abderrahmani A., Ferdaoussi M., Roduit R., Maurer F., Beckmann J.S., Kastrup J.S. et al., 2006. EMBO Journal, 25 (4) pp. 785-797. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8020128E6107]
2005
 
Malonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes.
Joly E., Bendayan M., Roduit R., Saha A.K., Ruderman N.B., Prentki M., 2005/12/05. FEBS letters, 579 (29) pp. 6581-6586. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_065F31F66709]
 
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.
Gremlich S., Nolan C., Roduit R., Burcelin R., Peyot M.L., Delghingaro-Augusto V., Desvergne B., Michalik L., Prentki M., Wahli W., 2005. Endocrinology, 146 (1) pp. 375-382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA00C2E702BB]
2004
 
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure
Abdelli S., Ansite J., Roduit R., Borsello T., Matsumoto I., Sawada T., Allaman-Pillet N., Henry H., Beckmann J. S., Hering B. J. et al., 2004/11. Diabetes, 53 (11) pp. 2815-23. Peer-reviewed.
[WoS][Pmid][serval:BIB_A39BC6421470]
 
Circadian regulation of islet genes involved in insulin production and secretion
Allaman-Pillet N., Roduit R., Oberson A., Abdelli S., Ruiz J., Beckmann J. S., Schorderet D. F., Bonny C., 2004/10. Molecular and Cellular Endocrinology, 226 (1-2) pp. 59-66. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0132435CECDD]
 
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.
Roduit R., Nolan C., Alarcon C., Moore P., Barbeau A., Delghingaro-Augusto V., Przybykowski E., Morin J., Massé F., Massie B. et al., 2004/04. Diabetes, 53 (4) pp. 1007-1019. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_55AB112846A9]
2003
 
Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.
Allaman-Pillet N., Størling J., Oberson A., Roduit R., Negri S., Sauser C., Nicod P., Beckmann J.S., Schorderet D.F., Mandrup-Poulsen T. et al., 2003/12. Journal of Biological Chemistry, 278 (49) pp. 48720-48726. Peer-reviewed.
[DOI][Pmid][serval:BIB_68939E882CF2]
 
DcR3/TR6 effectively prevents islet primary nonfunction after transplantation.
Wu Y., Han B., Luo H., Roduit R., Salcedo T.W., Moore P.A., Zhang J., Wu J., 2003/09. Diabetes, 52 (9) pp. 2279-2286. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_854D5CAB2E54]
 
Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death.
El-Assaad W., Buteau J., Peyot M.L., Nolan C., Roduit R., Hardy S., Joly E., Dbaibo G., Rosenberg L., Prentki M., 2003/09. Endocrinology, 144 (9) pp. 4154-4163. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CA5F8F5127F4]
2002
 
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes.
Prentki M., Joly E., El-Assaad W., Roduit R., 2002/12. Diabetes, 51 Suppl 3 pp. S405-13. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CE4D39ED85C8]
2001
 
A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice.
Roduit R., Masiello P., Wang S.P., Li H., Mitchell G.A., Prentki M., 2001/09. Diabetes, 50 (9) pp. 1970-1975. Peer-reviewed.
[WoS][Pmid][serval:BIB_BDCD70C7E210]
 
Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes.
Roh C., Roduit R., Thorens B., Fried S., Kandror K.V., 2001. Journal of Biological Chemistry, 276 (38) pp. 35990-35994.
[DOI][WoS][Pmid][serval:BIB_51C4A6E63228]
2000
 
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.
Roduit R., Morin J., Massé F., Segall L., Roche E., Newgard C.B., Assimacopoulos-Jeannet F., Prentki M., 2000/11/17. The Journal of biological chemistry, 275 (46) pp. 35799-35806. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7A52B4B54C22]
 
Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta -D-ribofuranoside.
Saha A.K., Schwarsin A.J., Roduit R., Masse F., Kaushik V., Tornheim K., Prentki M., Ruderman N.B., 2000/08/11. The Journal of biological chemistry, 275 (32) pp. 24279-24283. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6B8BB8DDA696]
1999
 
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells.
Buteau J., Roduit R., Susini S., Prentki M., 1999/07. Diabetologia, 42 (7) pp. 856-864. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6FE113E9F1AC]
 
Cloning and expression of rat pancreatic beta-cell malonyl-CoA decarboxylase.
Voilley N., Roduit R., Vicaretti R., Bonny C., Waeber G., Dyck J.R., Lopaschuk G.D., Prentki M., 1999. Biochemical journal, 340 (1) pp. 213-217. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2D74DBB3F265]
1998
 
Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland.
Pralong F.P., Roduit R., Waeber G., Castillo E., Mosimann F., Thorens B., Gaillard R.C., 1998. Endocrinology, 139 (10) pp. 4264-4268. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A5433DF9B2B1]
1997
 
Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin.
Roduit R., Thorens B., 1997/09/29. FEBS letters, 415 (2) pp. 179-182. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B9247F5BEEC7]
 
Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic beta cells. Comparison with the effects of fatty acids.
Gremlich S., Roduit R., Thorens B., 1997/02. Journal of Biological Chemistry, 272 (6) pp. 3216-3222. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_730623A8A041]
 
Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.
Waeber G., Calandra T., Roduit R., Haefliger J.A., Bonny C., Thompson N., Thorens B., Temler E., Meinhardt A., Bacher M. et al., 1997. Proceedings of the National Academy of Sciences of the United States of America, 94 (9) pp. 4782-4787. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_00FEA018BE42]
 
The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors.
Bonny C., Roduit R., Gremlich S., Nicod P., Thorens B., Waeber G., 1997. Molecular and Cellular Endocrinology, 135 (1) pp. 59-65. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5F54DCA36FB6]
1996
 
Prix Apollinaire Bouchardat 1996. Aspects moléculaires du contrôle de la sécrétion d'insuline [1996 Apollinaire Bouchardat Prize. Molecular aspects of control of insulin secretion].
Thorens B., Gremlich S., Roduit R., Widmann C., 1996. Journées Annuelles de Diabétologie De L'hôtel-dieu pp. 55-68.
[Pmid][serval:BIB_40D71E297088]
1994
 
Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells.
Thorens B., Roduit R., 1994/08. Biochemical Society Transactions, 22 (3) pp. 684-687.
[WoS][Pmid][serval:BIB_19429CB88950]
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