Nicolas Leuenberger

Publications | Phd and Masters theses

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45 publications

In press | 2024 | 2023 | 2022 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 |
In press
 
New Transcriptomic Biomarkers for Detection of the Recombinant Human Erythropoietin (rHuEPO) MirCERA in Horses.
Loup B., André F., Leuenberger N., Marchand A., Barnabé A., Delcourt V., Garcia P., Popot M.A., Bailly-Chouriberry L. Drug testing and analysis. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CC091BF74FB2]
2024
 
mRNA biomarkers sensitive and specific to micro-dose erythropoietin treatment at sea level and altitude.
Loria F., Breenfeldt Andersen A., Bejder J., Bonne T., Grabherr S., Kuuranne T., Leuenberger N., Baastrup Nordsborg N., 2024/11. Drug testing and analysis, 16 (11) pp. 1392-1401. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_69ECAA29DFB9]
 
Characterization of DNA concentration in urine and dried blood samples to detect the c.577 deletion within the EPO gene.
Leuenberger N., Jan N., Kuuranne T., Castella V., 2024/10. Drug testing and analysis, 16 (10) pp. 1225-1233. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E296BBDF60F2]
Comparison between standard hematological parameters and blood doping biomarkers in dried blood spots within the athlete population of Swiss Sport Integrity.
Oliveira J.A., Loria F., Schobinger C., Kuuranne T., Mumenthaler C., Leuenberger N., 2024. Frontiers in sports and active living, 6 p. 1452079. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CE750D2E5EFE]
 
Use of RNA biomarkers in the antidoping field.
Loria F., Grabherr S., Kuuranne T., Leuenberger N., 2024. Bioanalysis, 16 (10) pp. 475-484. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_560507E4D4FC]
2023
The effects of iron injection on blood doping biomarkers in dried blood spots.
Loria F., Maret E., Schobinger C., Kuuranne T., Grabherr S., Leuenberger N., 2023/04. Drug testing and analysis, 15 (4) pp. 444-448. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_11CBF09FF26F]
2022
A fast screening method for the detection of CERA in dried blood spots.
Rocca A., Martin L., Kuuranne T., Ericsson M., Marchand A., Leuenberger N., 2022/05. Drug testing and analysis, 14 (5) pp. 820-825. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1E2F82D48647]
The use of RNA-based 5'-aminolevulinate synthase 2 biomarkers in dried blood spots to detect recombinant human erythropoietin microdoses.
Loria F., Cox H.D., Voss S.C., Rocca A., Miller G.D., Townsend N., Georgakopoulos C., Eichner D., Kuuranne T., Leuenberger N., 2022/05. Drug testing and analysis, 14 (5) pp. 826-832. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F8CDD0BD3732]
Nouveautés dans la pathophysiologie et le traitement de l’anémie rénale [New insights in the pathophysiology and treatment of renal anemia]
Vultaggio P., Loria F., Fakhouri F., Leuenberger N., Pruijm M., 2022/03/02. Revue medicale suisse, 18 (771) pp. 358-363. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C48E5B4F4AB8]
 
Monitoring of hemoglobin and erythropoiesis-related mRNA with dried blood spots in athletes and patients.
Loria F., Stutz A.P., Rocca A., Grabherr S., Kuuranne T., Pruijm M., Leuenberger N., 2022/03. Bioanalysis, 14 (5) pp. 241-251. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3D12A0F09E1E]
2020
Automation of RNA-based biomarker extraction from dried blood spots for the detection of blood doping.
Loria F., Manfredi M., Reverter-Branchat G., Segura J., Kuuranne T., Leuenberger N., 2020/06. Bioanalysis, 12 (11) pp. 729-736. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3A0953F50D55]
Antidoping: From health tests to the athlete biological passport.
Saugy M., Leuenberger N., 2020/05. Drug testing and analysis, 12 (5) pp. 621-628. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_79A5A5E8831E]
Erythroferrone as a sensitive biomarker to detect stimulation of erythropoiesis.
Ramirez Cuevas K., Schobinger C., Gottardo E., Voss SC, Kuuranne T., Tissot JD, Favrat B., Townsend N., Leuenberger N., 2020/02. Drug testing and analysis, 12 (2) pp. 261-267. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B10331793EDC]
2019
 
Detection of Stimulated Erythropoiesis by the RNA-Based 5'-Aminolevulinate Synthase 2 Biomarker in Dried Blood Spot Samples.
Salamin O., Gottardo E., Schobinger C., Reverter-Branchat G., Segura J., Saugy M., Kuuranne T., Tissot J.D., Favrat B., Leuenberger N., 2019/12. Clinical chemistry, 65 (12) pp. 1563-1571. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9D4304062CD1]
2018
 
Erythropoietin as a performance-enhancing drug: Its mechanistic basis, detection, and potential adverse effects.
Salamin O., Kuuranne T., Saugy M., Leuenberger N., 2018/03/15. Molecular and cellular endocrinology, 464 pp. 75-87. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EA5301F9D7AD]
Transcriptomic biomarkers of altered erythropoiesis to detect autologous blood transfusion.
Salamin O., Mignot J., Kuuranne T., Saugy M., Leuenberger N., 2018/03. Drug testing and analysis, 10 (3) pp. 604-608. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D10E2B16EB63]
2017
 
Loop-mediated isothermal amplification (LAMP) as an alternative to PCR: A rapid on-site detection of gene doping.
Salamin O., Kuuranne T., Saugy M., Leuenberger N., 2017/11. Drug testing and analysis, 9 (11-12) pp. 1731-1737. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CEB715255F60]
 
Hepcidin as a potential biomarker for blood doping.
Leuenberger N., Bulla E., Salamin O., Nicoli R., Robinson N., Baume N., Saugy M., 2017/07. Drug testing and analysis, 9 (7) pp. 1093-1097. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_014250D79895]
 
RNA stabilized blood tubes to measure haemoglobin concentration.
Leuenberger N., Schobinger C., Salamin O., Saugy M., Kuuranne T., 2017/06. Drug testing and analysis, 9 (6) pp. 942-943. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_28B6B84A93CD]
2016
 
Impact of blood transfusion on gene expression in human reticulocytes.
Salamin O., Barras L., Robinson N., Baume N., Tissot J.D., Pitsiladis Y., Saugy M., Leuenberger N., 2016/10. American journal of hematology, 91 (10) pp. E460-1. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FB4B70292E18]
 
Autologous Blood Transfusion in Sports: Emerging Biomarkers.
Salamin O., De Angelis S., Tissot J.D., Saugy M., Leuenberger N., 2016/07. Transfusion medicine reviews, 30 (3) pp. 109-115. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F9D2D633F262]
 
Pre-analytical and analytical aspects of EDTA-plasma iron measurement.
Leuenberger N., Baume N., Robinson N., Saugy M., 2016/03. Drug testing and analysis, 8 (10) pp. 1077-1079. Peer-reviewed.
[DOI][Pmid][serval:BIB_F011B70B66BB]
 
Analytical Strategies for Doping Control Purposes: Needs, Challenges, and Perspectives.
Nicoli R., Guillarme D., Leuenberger N., Baume N., Robinson N., Saugy M., Veuthey J.L., 2016. Analytical Chemistry, 88 (1) pp. 508-523. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5578E6B171F0]
Circulating microRNA-122 as Potential Biomarker for Detection of Testosterone Abuse.
Salamin O., Jaggi L., Baume N., Robinson N., Saugy M., Leuenberger N., 2016. Plos One, 11 (5) pp. e0155248. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BF3A69FC165]
Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism.
Rando G., Tan C.K., Khaled N., Montagner A., Leuenberger N., Bertrand-Michel J., Paramalingam E., Guillou H., Wahli W., 2016. Elife, 5 pp. e28536. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FCF36597FFC7]
 
Hepcidin as a new biomarker for detecting autologous blood transfusion.
Leuenberger N., Barras L., Nicoli R., Robinson N., Baume N., Lion N., Barelli S., Tissot J.D., Saugy M., 2016. American Journal of Hematology, 91 (5) pp. 467-472. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2DDE07BF29A7]
 
Methods for Doping Detection.
Ponzetto F., Giraud S., Leuenberger N., Boccard J., Nicoli R., Baume N., Rudaz S., Saugy M., 2016. pp. 153-167 dans Sports Endocrinology, Karger.
[DOI][WoS][Pmid][serval:BIB_D46120D7FBBD]
 
Urinary di-(2-ethylhexyl) phthalate metabolites for detecting transfusion of autologous blood stored in plasticizer-free bags.
Leuenberger N., Barras L., Nicoli R., Robinson N., Baume N., Lion N., Barelli S., Tissot J.D., Saugy M., 2016. Transfusion, 56 (3) pp. 571-578. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_61E3BEE13EE8]
2015
Antidoping programme and biological monitoring before and during the 2014 FIFA World Cup Brazil.
Baume N., Jan N., Emery C., Mandanis B., Schweizer C., Giraud S., Leuenberger N., Marclay F., Nicoli R., Perrenoud L. et al., 2015. British Journal of Sports Medicine, 49 (9) pp. 614-622. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0ED34BBDF614]
 
Circulating microRNAs: The Future of Biomarkers in Anti-doping Field.
Leuenberger N., Saugy M., 2015. Advances In Experimental Medicine and Biology, 888 pp. 401-408. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D8FDA2824657]
2014
 
A fast automated screening method for the detection of blood transfusion in sports.
Leuenberger N., Ansermet C., Pottgiesser T., Baume N., Robinson N., Saugy M., Schumacher Y.O., 2014. Drug Testing and Analysis, 6 (11-12) pp. 1141-1143. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EB7D47262943]
 
Dopage : aspects médico-techniques
Baume N., Jan N., Leuenberger N., Mangin P., Marclay F., Robinson N., Saugy M., 2014. pp. 809-821 dans Droit de la santé et médecine légale chap. 81, Chêne-Bourg : Ed. Médecine et Hygiène.
[serval:BIB_D97EB18DE1B8]
 
Droit de la santé et médecine légale
La Harpe R., Ummel M., Dumoulin JF, Rotman S., Baume N., Egger C., Elger B., Favrat B., Fracasso T., Gehrig C. et al., 2014. 810, Chêne-Bourg : Médecine & Hygiène.
[serval:BIB_4F64621895B0]
2013
Circulating miRNAs: a new generation of anti-doping biomarkers.
Leuenberger N., Robinson N., Saugy M., 2013/12. Analytical and bioanalytical chemistry, 405 (30) pp. 9617-9623. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D1E1A08E5864]
Circulating microRNAs as biomarkers for detection of autologous blood transfusion.
Leuenberger N., Schumacher Y.O., Pradervand S., Sander T., Saugy M., Pottgiesser T., 2013. Plos One, 8 (6) pp. e66309. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_67101E35A815]
2012
 
Detection of erythropoiesis-stimulating agents in human anti-doping control: past, present and future.
Leuenberger N., Reichel C., Lasne F., 2012. Bioanalysis, 4 (13) pp. 1565-1575. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4276B53027BB]
2011
 
Circulating microRNAs as long-term biomarkers for the detection of erythropoiesis-stimulating agent abuse.
Leuenberger N., Jan N., Pradervand S., Robinson N., Saugy M., 2011. Drug Testing and Analysis, 3 (11-12) pp. 771-776. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1956234662DB]
 
How to confirm C.E.R.A. doping in athletes' blood?
Leuenberger N., Lamon S., Robinson N., Giraud S., Saugy M., 2011. Forensic science international, 213 (1-3) pp. 101-3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_47D435872930]
 
Methods for detection and confirmation of Hematide?/peginesatide in anti-doping samples.
Leuenberger N., Saugy J., Mortensen R.B., Schatz P.J., Giraud S., Saugy M., 2011. Forensic science international, 213 (1-3) pp. 15-19. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2FC1672D1C0F]
 
New insights into the role of PPARs.
Montagner A., Rando G., Degueurce G., Leuenberger N., Michalik L., Wahli W., 2011. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 85 (5) pp. 235-243. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AD83D596CCB8]
Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity.
Gachon F., Leuenberger N., Claudel T., Gos P., Jouffe C., Fleury Olela F., de Mollerat du Jeu X., Wahli W., Schibler U., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (12) pp. 4794-4799. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BE2B46D7941]
Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.
Tan C.K., Leuenberger N., Tan M.J., Yan Y.W., Chen Y., Kambadur R., Wahli W., Tan N.S., 2011. Diabetes, 60 (2) pp. 464-476. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2494301CF2DB]
2010
 
PPARα, a key regulator of hepatic energy homeostasis in health and disease
Leuenberger N., Wahli W., 2010. pp. 305-315 dans Dufour J.F., Clavien P.A. (eds.) Signaling Pathways in Liver Diseases, Springer-Verlag.
[DOI][serval:BIB_18B0CAFB2EF5]
 
Rapid affinity purification of erythropoietin from biological samples using disposable monoliths.
Lönnberg Maria, Dehnes Yvette, Drevin Malin, Garle Mats, Lamon Severine, Leuenberger Nicolas, Quach Trikien, Carlsson Jan, 2010. Journal of Chromatography. A, 1217 (45) pp. 7031-7037. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F291F8C35E0]
2009
 
Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice.
Leuenberger N., Pradervand S., Wahli W., 2009. Journal of Clinical Investigation, 119 (10) pp. 3138-3148. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_09D2CA4DF67C]
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