Leonore Wigger

Publications | Phd and Masters theses

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15 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2015 | 2013 |
Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner.
Kompotis K., Mang G.M., Hubbard J., Jimenez S., Emmenegger Y., Polysopoulos C., Hor C.N., Wigger L., Hébert S.S., Mongrain V. et al., 2024/01/16. Proceedings of the National Academy of Sciences of the United States of America, 121 (3) pp. e2220532121. Peer-reviewed.
 
Assessment of the Cardiac Noncoding Transcriptome by Single-Cell RNA Sequencing Identifies FIXER, a Conserved Profibrogenic Long Noncoding RNA.
Aghagolzadeh P., Plaisance I., Bernasconi R., Treibel T.A., Pulido Quetglas C., Wyss T., Wigger L., Nemir M., Sarre A., Chouvardas P. et al., 2023/08/29. Circulation, 148 (9) pp. 778-797. Peer-reviewed.
Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock.
Bignon Y., Wigger L., Ansermet C., Weger B.D., Lagarrigue S., Centeno G., Durussel F., Götz L., Ibberson M., Pradervand S. et al., 2023/04/17. The Journal of clinical investigation, 133 (8) pp. e167133. Peer-reviewed.
A combination of plasma membrane sterol biosynthesis and autophagy is required for shade-induced hypocotyl elongation.
Ince Y.Ç., Krahmer J., Fiorucci A.S., Trevisan M., Galvão V.C., Wigger L., Pradervand S., Fouillen L., Van Delft P., Genva M. et al., 2022/10/10. Nature communications, 13 (1) p. 5659. Peer-reviewed.
Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.
Sánchez-Archidona A.R., Cruciani-Guglielmacci C., Roujeau C., Wigger L., Lallement J., Denom J., Barovic M., Kassis N., Mehl F., Weitz J. et al., 2021/12. Molecular metabolism, 54 p. 101355. Peer-reviewed.
 
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes.
Wigger L., Barovic M., Brunner A.D., Marzetta F., Schöniger E., Mehl F., Kipke N., Friedland D., Burdet F., Kessler C. et al., 2021/07. Nature metabolism, 3 (7) pp. 1017-1031. Peer-reviewed.
 
Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patients.
Fontana P., Ibberson M., Stevenson B., Wigger L., Daali Y., Niknejad A., Mach F., Docquier M., Xenarios I., Cuisset T. et al., 2020/06. Journal of thrombosis and haemostasis, 18 (6) pp. 1425-1434. Peer-reviewed.
 
Dairy consumption is associated with lower plasma dihydroceramides in women from the D.E.S.I.R. cohort.
Fumeron F., Nicolas A., Bastard J.P., Fellahi S., Wigger L., Ibberson M., Cruciani-Guglielmacci C., Le Stunff H., Velho G., Magnan C. et al., 2020/04. Diabetes & metabolism, 46 (2) pp. 144-149. Peer-reviewed.
Sensory neuron lineage mapping and manipulation in the Drosophila olfactory system.
Chai P.C., Cruchet S., Wigger L., Benton R., 2019/02/07. Nature Communications, 10 (1) p. 643. Peer-reviewed.
System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells.
Wigger L., Casals-Casas C., Baruchet M., Trang K.B., Pradervand S., Naldi A., Desvergne B., 2019. PloS one, 14 (8) pp. e0220894. Peer-reviewed.
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.
Solimena M., Schulte A.M., Marselli L., Ehehalt F., Richter D., Kleeberg M., Mziaut H., Knoch K.P., Parnis J., Bugliani M. et al., 2018/03. Diabetologia, 61 (3) pp. 641-657. Peer-reviewed.
Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for <i>Elovl2</i> in glucose-induced insulin secretion.
Cruciani-Guglielmacci C., Bellini L., Denom J., Oshima M., Fernandez N., Normandie-Levi P., Berney X.P., Kassis N., Rouch C., Dairou J. et al., 2017/04. Molecular metabolism, 6 (4) pp. 340-351. Peer-reviewed.
Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.
Wigger L., Cruciani-Guglielmacci C., Nicolas A., Denom J., Fernandez N., Fumeron F., Marques-Vidal P., Ktorza A., Kramer W., Schulte A. et al., 2017/02/28. Cell reports, 18 (9) pp. 2269-2279. Peer-reviewed.
A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.
Mang G.M., Pradervand S., Du N.H., Arpat A.B., Preitner F., Wigger L., Gatfield D., Franken P., 2015. PLoS One, 10 (1) pp. e0116760.
 
Malaria haplotype frequency estimation.
Wigger L., Vogt J.E., Roth V., 2013. Statistics in Medicine, 32 (21) pp. 3737-3751.
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