Valeria Cagno

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59 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 |
Bithiazole inhibitors of PI4KB show broad-spectrum antiviral activity against different viral families.
Martina M.G., Carlen V., Van der Reysen S., Bianchi E., Cabella N., Crespan E., Radi M., Cagno V., 2024/11. Antiviral research, 231 p. 106003. Peer-reviewed.
 
Novel Inhibitors of SARS-CoV-2 RNA Identified through Virtual Screening.
Mathez G., Brancale A., Cagno V., 2024/08/12. Journal of chemical information and modeling, 64 (15) pp. 6190-6196. Peer-reviewed.
 
A reporter virus particle seroneutralization assay for tick-borne encephalitis virus overcomes ELISA limitations.
Ackermann-Gäumann R., Dentand A., Lienhard R., Saeed M., Speiser D.E., MacDonald M.R., Coste A.T., Cagno V., 2024/08. Journal of medical virology, 96 (8) pp. e29843. Peer-reviewed.
 
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections.
Barbieri F., Carlen V., Martina M.G., Sannio F., Cancade S., Perini C., Restori M., Crespan E., Maga G., Docquier J.D. et al., 2024/05/22. RSC medicinal chemistry, 15 (5) pp. 1589-1600. Peer-reviewed.
Benzene with Alkyl Chains Is a Universal Scaffold for Multivalent Virucidal Antivirals.
Zhu Y., Gasbarri M., Zebret S., Pawar S., Mathez G., Diderich J., Valencia-Camargo A.D., Russenberger D., Wang H., Silva PHJ et al., 2024/05/22. ACS central science, 10 (5) pp. 1012-1021. Peer-reviewed.
 
Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff
Han Kang Tee, Gregory Mathez, Valeria Cagno, Aleksandar Antanasijevic, Sophie Clément, Caroline Tapparel, 2024/02/25..
 
A reporter virus particle seroneutralization assay for tick-borne encephalitis virus overcomes ELISA limitations
Ackermann-Gäumann Rahel, Dentand Alexis, Lienhard Reto, Saeed Mohsan, MacDonald Margaret R., Coste Alix T, Cagno Valeria, 2024/01/23..
 
Non-Steroidal Estrogens Inhibit Influenza Virus by Interacting with Hemagglutinin and Preventing Viral Fusion.
Franzi E., Mathez G., Dinant S., Deloizy C., Kaiser L., Tapparel C., Le Goffic R., Cagno V., 2023/10/19. International journal of molecular sciences, 24 (20). Peer-reviewed.
Small Molecules Targeting Viral RNA.
Mathez G., Cagno V., 2023/08/31. International journal of molecular sciences, 24 (17) p. 13500. Peer-reviewed.
 
Variant enterovirus A71 found in immune-suppressed patient binds to heparan sulfate and exhibits neurotropism in B-cell-depleted mice
Weng Kuo-Feng, Tee Han Kang, Tseligka Eirini D., Cagno Valeria, Mathez Gregory, Rosset Stéphane, Nagamine Claude M., Sarnow Peter, Kirkegaard Karla, Tapparel Vu Caroline, 2023/04. Cell Reports.
Alpha and Omicron SARS-CoV-2 Adaptation in an Upper Respiratory Tract Model.
Mathez G., Pillonel T., Bertelli C., Cagno V., 2022/12/20. Viruses, 15 (1) p. 13. Peer-reviewed.
Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed -1 ribosomal frameshifting.
Varricchio C., Mathez G., Pillonel T., Bertelli C., Kaiser L., Tapparel C., Brancale A., Cagno V., 2022/12. Antiviral research, 208 p. 105452. Peer-reviewed.
Lignin: A Sustainable Antiviral Coating Material.
Boarino A., Wang H., Olgiati F., Artusio F., Özkan M., Bertella S., Razza N., Cagno V., Luterbacher J.S., Klok H.A. et al., 2022/10/24. ACS sustainable chemistry & engineering, 10 (42) pp. 14001-14010. Peer-reviewed.
An anti-influenza combined therapy assessed by single cell RNA-sequencing.
Medaglia C., Kolpakov I., Zwygart A.C., Zhu Y., Constant S., Huang S., Cagno V., Dermitzakis E.T., Stellacci F., Xenarios I. et al., 2022/10/10. Communications biology, 5 (1) p. 1075. Peer-reviewed.
 
Polyanionic Amphiphilic Dendritic Polyglycerols as Broad-Spectrum Viral Inhibitors with a Virucidal Mechanism
Mohammadifar Ehsan, Gasbarri Matteo, Cagno Valeria, Achazi Katharina, Tapparel Caroline, Haag Rainer, Stellacci Francesco, 2022/03/14. Biomacromolecules, 23 (3) pp. 983-991.
 
Inhibitors of acyl protein thioesterases against microbial infections
Cagno Valeria, Tapparel Caroline, Mesquita Francisco, Van der Goot Gisou, 2022..
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma.
Fenwick C., Turelli P., Pellaton C., Farina A., Campos J., Raclot C., Pojer F., Cagno V., Nusslé S.G., D'Acremont V. et al., 2021/08/04. Science translational medicine, 13 (605) pp. eabi8452. Peer-reviewed.
Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro.
Cagno V., Medaglia C., Cerny A., Cerny T., Zwygart A.C., Cerny E., Tapparel C., 2021/07/12. Scientific reports, 11 (1) p. 14295. Peer-reviewed.
 
Viruses Like Sugars: How to Assess Glycan Involvement in Viral Attachment.
Mathez G., Cagno V., 2021/06/07. Microorganisms, 9 (6) p. 1238. Peer-reviewed.
 
The tyrosine kinase inhibitor nilotinib inhibits SARS-CoV-2 in vitro.
Cagno V., Magliocco G., Tapparel C., Daali Y., 2021/04. Basic & clinical pharmacology & toxicology, 128 (4) pp. 621-624. Peer-reviewed.
 
Non‐Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo
Kocabiyik Ozgun, Cagno Valeria, Silva Paulo Jacob, Zhu Yong, Sedano Laura, Bhide Yoshita, Mettier Joelle, Medaglia Chiara, Da Costa Bruno, Constant Samuel et al., 2021/02. Advanced Science, 8 (3).
 
A novel anti-influenza combined therapy assessed by single cell RNA-sequencing
Medaglia Chiara, Kolpakov Ilya, Zhu Yong, Constant Samuel, Huang Song, Zwygart Arnaud Charles-Antoine, Cagno Valeria, Dermitzakis Emmanouil T., Stellacci Francesco, Xenarios Ioannis et al., 2021..
Clinical severe acute respiratory syndrome coronavirus 2 isolation and antiviral testing.
Mathez G., Cagno V., 2021. Antiviral chemistry & chemotherapy, 29 p. 20402066211061063. Peer-reviewed.
 
Do we need a contact tracing app?
Maccari Leonardo, Cagno Valeria, 2021/01. Computer Communications, 166 pp. 9-18.
 
SARS-CoV-2 Inhibition by Sulfonated Compounds.
Gasbarri M., V'kovski P., Torriani G., Thiel V., Stellacci F., Tapparel C., Cagno V., 2020/11/30. Microorganisms, 8 (12) p. 1894. Peer-reviewed.
 
Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses.
Cagno V., Gasbarri M., Medaglia C., Gomes D., Clement S., Stellacci F., Tapparel C., 2020/11/17. Antimicrobial agents and chemotherapy, 64 (12). Peer-reviewed.
 
SARS-CoV-2 cellular tropism.
Cagno V., 2020/05. The Lancet. Microbe, 1 (1) pp. e2-e3. Peer-reviewed.
 
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense
Civra Andrea, Colzani Mara, Cagno Valeria, Francese Rachele, Leoni Valerio, Aldini Giancarlo, Lembo David, Poli Giuseppe, 2020/03. Free Radical Biology and Medicine, 149 pp. 30-36.
 
Modified cyclodextrins as broad-spectrum antivirals
Jones Samuel T, Cagno Valeria, Janeček Matej, Ortiz Daniel, Gasilova Natalia, Piret Jocelyne, Gasbarri Matteo, Constant David A., Han Yanxiao, Vuković Lela et al., 2020/01/31. Science Advances.
 
Growth of Zika virus in human reconstituted respiratory, intestinal, vaginal and neural tissues
Cagno V., Tseligka E.D., Bettex Q., Huang S., Constant S., Tapparel C., 2019/08. Clinical Microbiology and Infection, 25 (8) pp. 1042.e1-1042.e4.
 
Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?
Cagno Valeria, Tseligka Eirini D., Jones Samuel T., Tapparel Caroline, 2019/07/01. Viruses, 11 (7) p. 596.
 
Novel broad spectrum virucidal molecules against enveloped viruses
Cagno Valeria, Tintori Cristina, Civra Andrea, Cavalli Roberta, Tiberi Marika, Botta Lorenzo, Brai Annalaura, Poli Giulio, Tapparel Caroline, Lembo David et al., 2018/12/07. PLOS ONE, 13 (12) pp. e0208333.
 
25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes
Civra Andrea, Francese Rachele, Gamba Paola, Testa Gabriella, Cagno Valeria, Poli Giuseppe, Lembo David, 2018/10. Redox Biology, 19 pp. 318-330.
 
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
Tintori Cristina, Iovenitti Giulia, Ceresola Elisa Rita, Ferrarese Roberto, Zamperini Claudio, Brai Annalaura, Poli Giulio, Dreassi Elena, Cagno Valeria, Lembo David et al., 2018/06/05. PLOS ONE, 13 (6) pp. e0198478.
 
Propagation of respiratory viruses in human airway epithelia reveals persistent virus-specific signatures.
Essaidi-Laziosi M., Brito F., Benaoudia S., Royston L., Cagno V., Fernandes-Rocha M., Piuz I., Zdobnov E., Huang S., Constant S. et al., 2018/06. The Journal of allergy and clinical immunology, 141 (6) pp. 2074-2084. Peer-reviewed.
 
The traditional use of Vachellia nilotica for sexually transmitted diseases is substantiated by the antiviral activity of its bark extract against sexually transmitted viruses
Donalisio Manuela, Cagno Valeria, Civra Andrea, Gibellini Davide, Musumeci Giuseppina, Rittà Massimo, Ghosh Manik, Lembo David, 2018/03. Journal of Ethnopharmacology, 213 pp. 403-408.
 
Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism
Cagno Valeria, Andreozzi Patrizia, D'Alicarnasso Marco, Jacob Silva Paulo, Mueller Marie, Galloux Marie, Le Goffic Ronan, Jones Samuel T., Vallino Marta, Hodek Jan et al., 2018/02/01. Nature Materials, 17 (2) pp. 195-203.
 
In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus
Civra Andrea, Francese Rachele, Sinato Davide, Donalisio Manuela, Cagno Valeria, Rubiolo Patrizia, Ceylan Ramazan, Uysal Ahmet, Zengin Gokhan, Lembo David, 2017/12. BMC Complementary and Alternative Medicine, 17 (1).
 
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol
Cagno Valeria, Civra Andrea, Rossin Daniela, Calfapietra Simone, Caccia Claudio, Leoni Valerio, Dorma Nicholas, Biasi Fiorella, Poli Giuseppe, Lembo David, 2017/08. Redox Biology, 12 pp. 522-527.
 
In vitro anti-herpes simplex virus-2 activity of Salvia desoleana Atzei & V. Picci essential oil
Cagno Valeria, Sgorbini Barbara, Sanna Cinzia, Cagliero Cecilia, Ballero Mauro, Civra Andrea, Donalisio Manuela, Bicchi Carlo, Lembo David, Rubiolo Patrizia, 2017/02/16. PLOS ONE, 12 (2) pp. e0172322.
 
M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures
Musumeci Giuseppina, Bon Isabella, Lembo David, Cagno Valeria, Re Maria Carla, Signoretto Caterina, Diani Erica, Lopalco Lucia, Pastori Claudia, Martin Loïc et al., 2017/02/01. Scientific Reports, 7 (1).
 
Ficus religiosa L. bark extracts inhibit infection by herpes simplex virus type 2 in vitro
Ghosh Manik, Civra Andrea, Rittà Massimo, Cagno Valeria, Mavuduru Siva Ganesh, Awasthi Preeti, Lembo David, Donalisio Manuela, 2016/12. Archives of Virology, 161 (12) pp. 3509-3514.
 
Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months
Pelliccia Maria, Andreozzi Patrizia, Paulose Jayson, D'Alicarnasso Marco, Cagno Valeria, Donalisio Manuela, Civra Andrea, Broeckel Rebecca M., Haese Nicole, Jacob Silva Paulo et al., 2016/11/30. Nature Communications, 7 (1).
 
Linear biocompatible glyco-polyamidoamines as dual action mode virus infection inhibitors with potential as broad-spectrum microbicides for sexually transmitted diseases
Mauro Nicolò, Ferruti Paolo, Ranucci Elisabetta, Manfredi Amedea, Berzi Angela, Clerici Mario, Cagno Valeria, Lembo David, Palmioli Alessandro, Sattin Sara, 2016/09/19. Scientific Reports, 6 (1).
 
Oxysterols: An emerging class of broad spectrum antiviral effectors
Lembo David, Cagno Valeria, Civra Andrea, Poli Giuseppe, 2016/06. Molecular Aspects of Medicine, 49 pp. 23-30.
 
The AGMA1 poly(amidoamine) inhibits the infectivity of herpes simplex virus in cell lines, in human cervicovaginal histocultures, and in vaginally infected mice
Donalisio Manuela, Quaranta Paola, Chiuppesi Flavia, Pistello Mauro, Cagno Valeria, Cavalli Roberta, Volante Marco, Bugatti Antonella, Rusnati Marco, Ranucci Elisabetta et al., 2016/04. Biomaterials, 85 pp. 40-53.
 
Hexagonal-shaped chondroitin sulfate self-assemblies have exalted anti-HSV-2 activity
Galus Aurélia, Mallet Jean-Maurice, Lembo David, Cagno Valeria, Djabourov Madeleine, Lortat-Jacob Hugues, Bouchemal Kawthar, 2016/01. Carbohydrate Polymers, 136 pp. 113-120.
 
Ficus religiosa L. bark extracts inhibit human rhinovirus and respiratory syncytial virus infection in vitro
Cagno Valeria, Civra Andrea, Kumar Ravi, Pradhan Subhankar, Donalisio Manuela, Sinha Barij Nayan, Ghosh Manik, Lembo David, 2015/12. Journal of Ethnopharmacology, 176 pp. 252-257.
 
The Agmatine-Containing Poly(Amidoamine) Polymer AGMA1 Binds Cell Surface Heparan Sulfates and Prevents Attachment of Mucosal Human Papillomaviruses
Cagno Valeria, Donalisio Manuela, Bugatti Antonella, Civra Andrea, Cavalli Roberta, Ranucci Elisabetta, Ferruti Paolo, Rusnati Marco, Lembo David, 2015/09. Antimicrobial Agents and Chemotherapy, 59 (9) pp. 5250-5259.
 
In vitro evaluation of the antiviral properties of Shilajit and investigation of its mechanisms of action
Cagno Valeria, Donalisio Manuela, Civra Andrea, Cagliero Cecilia, Rubiolo Patrizia, Lembo David, 2015/05. Journal of Ethnopharmacology, 166 pp. 129-134.
 
Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol
Civra Andrea, Cagno Valeria, Donalisio Manuela, Biasi Fiorella, Leonarduzzi Gabriella, Poli Giuseppe, Lembo David, 2014/12/15. Scientific Reports, 4 (1).
 
Agmatine-Containing Poly(amidoamine)s as a Novel Class of Antiviral Macromolecules: Structural Properties and <i>In Vitro</i> Evaluation of Infectivity Inhibition
Donalisio Manuela, Ranucci Elisabetta, Cagno Valeria, Civra Andrea, Manfredi Amedea, Cavalli Roberta, Ferruti Paolo, Lembo David, 2014/10. Antimicrobial Agents and Chemotherapy, 58 (10) pp. 6315-6319.
 
Auto-associative heparin nanoassemblies: A biomimetic platform against the heparan sulfate-dependent viruses HSV-1, HSV-2, HPV-16 and RSV
Lembo David, Donalisio Manuela, Laine Claire, Cagno Valeria, Civra Andrea, Bianchini Elsa P., Zeghbib Narimane, Bouchemal Kawthar, 2014/09. European Journal of Pharmaceutics and Biopharmaceutics, 88 (1) pp. 275-282.
 
Highly Sulfated K5 Escherichia coli Polysaccharide Derivatives Inhibit Respiratory Syncytial Virus Infectivity in Cell Lines and Human Tracheal-Bronchial Histocultures
Cagno Valeria, Donalisio Manuela, Civra Andrea, Volante Marco, Veccelli Elena, Oreste Pasqua, Rusnati Marco, Lembo David, 2014/08. Antimicrobial Agents and Chemotherapy, 58 (8) pp. 4782-4794.
 
Ethyl 1,8-Naphthyridone-3-carboxylates Downregulate Human Papillomavirus-16 E6 and E7 Oncogene Expression
Donalisio Manuela, Massari Serena, Argenziano Monica, Manfroni Giuseppe, Cagno Valeria, Civra Andrea, Sabatini Stefano, Cecchetti Violetta, Loregian Arianna, Cavalli Roberta et al., 2014/07/10. Journal of Medicinal Chemistry, 57 (13) pp. 5649-5663.
 
Preparation, characterization and in vitro antiviral activity evaluation of foscarnet-chitosan nanoparticles
Russo E., Gaglianone N., Baldassari S., Parodi B., Cafaggi S., Zibana C., Donalisio M., Cagno V., Lembo D., Caviglioli G., 2014/06. Colloids and Surfaces B: Biointerfaces, 118 pp. 117-125.
 
Inactivation of high-risk human papillomaviruses by Holder pasteurization: implications for donor human milk banking
Donalisio Manuela, Cagno Valeria, Vallino Marta, Moro Guido E., Arslanoglu Sertac, Tonetto Paola, Bertino Enrico, Lembo David, 2014/01/01. jpme, 42 (1) pp. 1-8.
 
In vitro anti-Herpes simplex virus activity of crude extract of the roots of Nauclea latifolia Smith (Rubiaceae)
Donalisio Manuela, Nana Huguette Magnifouet, Ngono Ngane Rosalie Annie, Gatsing Donatien, Tiabou Tchinda Alembert, Rovito Roberta, Cagno Valeria, Cagliero Cecilia, Boyom Fabrice Fekam, Rubiolo Patrizia et al., 2013/12. BMC Complementary and Alternative Medicine, 13 (1).
 
Inhibition of Human Respiratory Syncytial Virus Infectivity by a Dendrimeric Heparan Sulfate-Binding Peptide
Donalisio Manuela, Rusnati Marco, Cagno Valeria, Civra Andrea, Bugatti Antonella, Giuliani Andrea, Pirri Giovanna, Volante Marco, Papotti Mauro, Landolfo Santo et al., 2012/10. Antimicrobial Agents and Chemotherapy, 56 (10) pp. 5278-5288.
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