Thierry Roger

Publications | Phd and Masters theses

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164 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1998 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 |
2024
 
Author Correction: Using weight loss to predict outcome and define a humane endpoint in preclinical sepsis studies.
Brochut M., Heinonen T., Snäkä T., Gilbert C., Le Roy D., Roger T., 2024/10/24. Scientific reports, 14 (1) p. 25245. Peer-reviewed.
[DOI][Pmid][serval:BIB_F5E9472F7B95]
Using weight loss to predict outcome and define a humane endpoint in preclinical sepsis studies.
Brochut M., Heinonen T., Snäkä T., Gilbert C., Le Roy D., Roger T., 2024/09/10. Scientific reports, 14 (1) p. 21150. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7BC6B7F85EE9]
 
Towards personalized medicine: a scoping review of immunotherapy in sepsis.
Slim M.A., van Mourik N., Bakkerus L., Fuller K., Acharya L., Giannidis T., Dionne J.C., Oczkowski SJW, Netea M.G., Pickkers P. et al., 2024/05/28. Critical care, 28 (1) p. 183. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3C6BCD297355]
Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients.
Schrijver I.T., Herderschee J., Théroude C., Kritikos A., Leijte G., Le Roy D., Brochut M., Chiche J.D., Perreau M., Pantaleo G. et al., 2024/02/08. Cells, 13 (4). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AAE7B79746C8]
2023
 
Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations.
Katzmarski N., Domínguez-Andrés J., Cirovic B., Renieris G., Ciarlo E., Le Roy D., Lepikhov K., Kattler K., Gasparoni G., Händler K. et al., 2023/02..
[DOI][WoS][Pmid][serval:BIB_69516D01373A]
Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity.
Pfefferlé M., Dubach I.L., Buzzi R.M., Dürst E., Schulthess-Lutz N., Baselgia L., Hansen K., Imhof L., Koernig S., Le Roy D. et al., 2023/01. Journal for immunotherapy of cancer, 11 (1) pp. e005718. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_255273ACC947]
Dysregulated monocyte-derived macrophage response to Group B Streptococcus in newborns.
Ravi D., Ntinopoulou E., Guetta N., Weier M., Vogel V., Spellerberg B., Sendi P., Gremlich S., Roger T., Giannoni E., 2023. Frontiers in immunology, 14 p. 1268804. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1B4D508C3CFE]
Editorial: Beneficial and pathological roles of myeloid cells during COVID-19.
Sharma L., Sengupta S., Roger T., 2023. Frontiers in immunology, 14 p. 1194826. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BCCBC012906E]
2022
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis.
Peters VBM, Arulkumaran N., Melis M.J., Gaupp C., Roger T., Shankar-Hari M., Singer M., 2022/12/06. Life, 12 (12) p. 2034. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_21B64ED7EB7B]
COVID-19 rapidly increases MDSCs and prolongs innate immune dysfunctions.
Schrijver I.T., Théroude C., Antonakos N., Regina J., Le Roy D., Bart P.A., Chiche J.D., Perreau M., Pantaleo G., Calandra T. et al., 2022/10. European journal of immunology, 52 (10) pp. 1676-1679. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CE51282F926C]
Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome: a randomized clinical trial.
Karakike E., Scicluna B.P., Roumpoutsou M., Mitrou I., Karampela N., Karageorgos A., Psaroulis K., Massa E., Pitsoulis A., Chaloulis P. et al., 2022/06/18. Critical care, 26 (1) p. 183. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AD06BCD240B9]
High-dimensional immune phenotyping of blood cells by mass cytometry in patients infected with hepatitis C virus.
Herderschee J., Heinonen T., Fenwick C., Schrijver I.T., Ohmiti K., Moradpour D., Cavassini M., Pantaleo G., Roger T., Calandra T. et al., 2022/04. Clinical microbiology and infection, 28 (4) pp. 611.e1-611.e7. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_300AF1BADC64]
Stapled Porcine Pericardium Displays Lower Infectivity In Vitro Than Native and Sutured Porcine Pericardium.
Del Tatto B., Le Roy D., Lambelet M., Corpataux J.M., Chakfé N., Giulieri S., Allagnat F., Roger T., Saucy F., 2022/04. The Journal of surgical research, 272 pp. 132-138. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17ED46F3E2BE]
High levels of monocytic myeloid-derived suppressor cells are associated with favorable outcome in patients with pneumonia and sepsis with multi-organ failure.
Schrijver I.T., Karakike E., Théroude C., Baumgartner P., Harari A., Giamarellos-Bourboulis E.J., Calandra T., Roger T., 2022/02/11. Intensive care medicine experimental, 10 (1) p. 5. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_79AC142AD176]
Macrophage migration inhibitory factor is overproduced through EGR1 in TET2<sup>low</sup> resting monocytes.
Pronier E., Imanci A., Selimoglu-Buet D., Badaoui B., Itzykson R., Roger T., Jego C., Naimo A., Francillette M., Breckler M. et al., 2022/02/03. Communications biology, 5 (1) p. 110. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_36E9A0EE1C81]
Reply to: 'Lack of evidence for intergenerational inheritance of immune resistance to infections'.
Katzmarski N., Domínguez-Andrés J., Cirovic B., Renieris G., Ciarlo E., Le Roy D., Lepikhov K., Kattler K., Gasparoni G., Händler K. et al., 2022/02. Nature immunology, 23 (2) pp. 208-209. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_253CFE3F8D18]
Modes of action and diagnostic value of miRNAs in sepsis.
Antonakos N., Gilbert C., Théroude C., Schrijver I.T., Roger T., 2022. Frontiers in immunology, 13 p. 951798. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4DC5945A7D32]
2021
 
Transmission of trained immunity and heterologous resistance to infections across generations.
Katzmarski N., Domínguez-Andrés J., Cirovic B., Renieris G., Ciarlo E., Le Roy D., Lepikhov K., Kattler K., Gasparoni G., Händler K. et al., 2021/11. Nature immunology, 22 (11) pp. 1382-1390. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_66EB4A759670]
The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients.
Perreau M., Suffiotti M., Marques-Vidal P., Wiedemann A., Levy Y., Laouénan C., Ghosn J., Fenwick C., Comte D., Roger T. et al., 2021/08/09. Nature communications, 12 (1) p. 4888. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D985FAB1BA6B]
Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway.
Ives A., Le Roy D., Théroude C., Bernhagen J., Roger T., Calandra T., 2021/05. FASEB journal, 35 (5) pp. e21418. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8D96EF9801E0]
Editorial: Macrophage Plasticity in Sterile and Pathogen-Induced Inflammation.
Kourtzelis I., Hewitson J., Roger T., 2021. Frontiers in immunology, 12 p. 823023. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D36347678BC5]
The Long Pentraxin PTX3 Controls Klebsiella Pneumoniae Severe Infection.
Asgari F., Supino D., Parente R., Polentarutti N., Stravalaci M., Porte R., Pasqualini F., Barbagallo M., Perucchini C., Recordati C. et al., 2021. Frontiers in immunology, 12 p. 666198. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6D2FF85E1166]
Trained Immunity Confers Prolonged Protection From Listeriosis.
Théroude C., Reverte M., Heinonen T., Ciarlo E., Schrijver I.T., Antonakos N., Maillard N., Pralong F., Le Roy D., Roger T., 2021. Frontiers in immunology, 12 p. 723393. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4EC9EEDD0004]
2020
Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections.
Ciarlo E., Heinonen T., Théroude C., Asgari F., Le Roy D., Netea M.G., Roger T., 2020/11/09. The Journal of infectious diseases, 222 (11) pp. 1869-1881. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_98E5CDC87421]
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality.
Demarco B., Grayczyk J.P., Bjanes E., Le Roy D., Tonnus W., Assenmacher C.A., Radaelli E., Fettrelet T., Mack V., Linkermann A. et al., 2020/11. Science advances, 6 (47) pp. eabc3465. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1DC0C3FF12E6]
Editorial: The Immunology of Sepsis-Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment.
Schlapbach L.J., Trück J., Roger T., 2020. Frontiers in immunology, 11 p. 1263. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_D062C43F2CDE]
2019
Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.
Giel-Moloney M., Esteban M., Oakes B.H., Vaine M., Asbach B., Wagner R., Mize G.J., Spies A.G., McElrath J., Perreau M. et al., 2019/12/27. Scientific reports, 9 (1) p. 20005. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_576063A9C68A]
Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes.
Alibashe-Ahmed M., Roger T., Serre-Beinier V., Berishvili E., Reith W., Bosco D., Berney T., 2019/06/28. Scientific reports, 9 (1) p. 9380. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9509A2FF11D8]
Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia.
Heinonen T., Ciarlo E., Rigoni E., Regina J., Le Roy D., Roger T., 2019. Frontiers in immunology, 10 p. 2713. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_393C04540461]
Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.
Heinonen T., Ciarlo E., Le Roy D., Roger T., 2019. Frontiers in immunology, 10 p. 2341. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4761B3798751]
Myeloid-Derived Suppressor Cells in Sepsis.
Schrijver I.T., Théroude C., Roger T., 2019. Frontiers in immunology, 10 p. 327. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_31178C23B5D8]
2018
 
The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size.
Fuchs K., Cardona Gloria Y., Wolz O.O., Herster F., Sharma L., Dillen C.A., Täumer C., Dickhöfer S., Bittner Z., Dang T.M. et al., 2018/12. EMBO reports, 19 (12). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DF9779D4CD31]
 
Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) Activation Balance Astrocyte Polarization into a Proinflammatory Phenotype.
Rosciszewski G., Cadena V., Murta V., Lukin J., Villarreal A., Roger T., Ramos A.J., 2018/05. Molecular neurobiology, 55 (5) pp. 3875-3888. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C927CCACF783]
IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns.
Schneider A., Weier M., Herderschee J., Perreau M., Calandra T., Roger T., Giannoni E., 2018. Frontiers in immunology, 9 p. 1597. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_655C09751DD5]
Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections.
Heinonen T., Ciarlo E., Théroude C., Pelekanou A., Herderschee J., Le Roy D., Roger T., 2018. Frontiers in immunology, 9 p. 2675. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_39701912842C]
2017
Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X.
Ferreira Lopes S., Vacher G., Ciarlo E., Savova-Bianchi Dessislava, Roger T., Niculita-Hirzel Hélène, 2017/10/25. Toxins, 9 (11) pp. 337 [1-14]. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B864F309B1AF]
Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.
Ciarlo E., Heinonen T., Lugrin J., Acha-Orbea H., Le Roy D., Auwerx J., Roger T., 2017/06/20. Scientific reports, 7 (1) p. 3853. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CE9836DB152C]
Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life.
Roger T., Schlapbach L.J., Schneider A., Weier M., Wellmann S., Marquis P., Vermijlen D., Sweep F.C., Leng L., Bucala R. et al., 2017. Frontiers in immunology, 8 p. 26. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_41DBC4B46D6E]
Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination.
Choteau L., Vancraeyneste H., Le Roy D., Dubuquoy L., Romani L., Jouault T., Poulain D., Sendid B., Calandra T., Roger T. et al., 2017. Gut pathogens, 9 p. 9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_98BFEF63331E]
Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection.
Ciarlo E., Heinonen T., Théroude C., Herderschee J., Mombelli M., Lugrin J., Pfefferlé M., Tyrrell B., Lensch S., Acha-Orbea H. et al., 2017. Frontiers in immunology, 8 p. 1037. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_82B331441F15]
The Anticancer Peptide TAT-RasGAP317-326 Exerts Broad Antimicrobial Activity.
Heulot M., Jacquier N., Aeby S., Le Roy D., Roger T., Trofimenko E., Barras D., Greub G., Widmann C., 2017. Frontiers in microbiology, 8 p. 994. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_949E09781E9B]
2016
Frequent occupational exposure to Fusarium mycotoxins of workers in the Swiss grain industry
Niculita-Hirzel Hélène, Hantier Grégoire, Storti Ferdinand, Plateel Gregory, Roger Thierry, 2016/12/12. Toxins, 8 (370) pp. [1-10]. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4EEAB411CCBE]
Le facteur d’inhibition de la migration des macrophages (MIF), un régulateur de la réponse immunitaire innée néonatale [Macrophage migration inhibitory factor (MIF), a regulator of neonatal innate immune response]
Giannoni É., Schneider A., Calandra T., Roger T., 2016/12. Medecine sciences : M/S, 32 (12) pp. 1062-1064. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0D720EF0B4DF]
Impact of the microbial derived short chain fatty acid propionate on host susceptibility to bacterial and fungal infections in vivo.
Ciarlo E., Heinonen T., Herderschee J., Fenwick C., Mombelli M., Le Roy D., Roger T., 2016/11/29. Scientific reports, 6 p. 37944. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CB627C7BE2E8]
Novel strategies for targeting innate immune responses to influenza.
Shirey K.A., Lai W., Patel M.C., Pletneva L.M., Pang C., Kurt-Jones E., Lipsky M., Roger T., Calandra T., Tracey K.J. et al., 2016/09. Mucosal immunology, 9 (5) pp. 1173-1182. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_0694E43E4827]
Innate immune defects in HIV permissive cell lines.
Rausell A., Muñoz M., Martinez R., Roger T., Telenti A., Ciuffi A., 2016/06/27. Retrovirology, 13 (1) p. 43. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_9559801F9747]
Effets toxiques des trichotecens de type B sur les cellules respiratoires humaines
Niculita-Hirzel Hélène, Ferreira Silvia, Vacher Gaëlle, Roger Thierry, 2016. p. 32 dans Mycotoxines 2016 : 6ème journée Mycotoxines, 15 et 16 mars 2016, Ecole nationale supérieure d'agronomie, Toulouse.
[URN][serval:BIB_AE089A13301C]
Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis.
Savva A., Brouwer M.C., Roger T., Valls Serón M., Le Roy D., Ferwerda B., van der Ende A., Bochud P.Y., van de Beek D., Calandra T., 2016. Proceedings of the National Academy of Sciences of the United States of America, 113 (13) pp. 3597-3602. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5662A8140129]
 
High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates.
Roger T., Schneider A., Weier M., Sweep F.C., Le Roy D., Bernhagen J., Calandra T., Giannoni E., 2016. Proceedings of the National Academy of Sciences of the United States of America, 113 (8) pp. E997-E1005. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FFABE5545203]
Mouse Model of Respiratory Tract Infection Induced by Waddlia chondrophila.
Pilloux L., LeRoy D., Brunel C., Roger T., Greub G., 2016. Plos One, 11 (3) pp. e0150909. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EF5484090AE6]
 
Screening the Impact of Sirtuin Inhibitors on Inflammatory and Innate Immune Responses of Macrophages and in a Mouse Model of Endotoxic Shock.
Ciarlo E., Roger T., 2016. Methods in molecular biology, 1436 pp. 313-334. Peer-reviewed.
[DOI][Pmid][serval:BIB_6089D37EA0E6]
Study of Early Elevated Gas6 Plasma Level as a Predictor of Mortality in a Prospective Cohort of Patients with Sepsis.
Stalder G., Que Y.A., Calzavarini S., Burnier L., Kosinski C., Ballabeni P., Roger T., Calandra T., Duchosal M.A., Liaudet L. et al., 2016. PloS one, 11 (10) pp. e0163542. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_AE9847158368]
2015
 
Emerging single-cell technologies in immunology.
Herderschee J., Fenwick C., Pantaleo G., Roger T., Calandra T., 2015. Journal of Leukocyte Biology, 98 (1) pp. 23-32. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B577FB613E4C]
Immune responses to airborne fungi and non-invasive airway diseases.
Vacher Gaëlle, Niculita-Hirzel Hélène, Roger Thierry, 2015. Seminars in Immunopathology, 37 (2) pp. 83-96.
[URN][DOI][WoS][Pmid][serval:BIB_8A4D897B60AF]
 
Innate immune sensing of Fusarium culmorum by mouse dendritic cells
Vacher Gaëlle, Ciarlo E., Savova-Bianchi Dessislava, Le Roy D., Hantier Grégoire, Niculita-Hirzel Hélène, Roger T., 2015. Journal of Toxicology and Environmental Health. Part A, 78 (13-14) pp. 871-885. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_024086D0C669]
Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins.
Delaloye J., Filali-Mouhim A., Cameron M.J., Haddad E.K., Harari A., Goulet J.P., Gomez C.E., Perdiguero B., Esteban M., Pantaleo G. et al., 2015. Journal of Virology, 89 (7) pp. 3819-3832. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3F54B19290C2]
TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26.
Meller S., Di Domizio J., Voo K.S., Friedrich H.C., Chamilos G., Ganguly D., Conrad C., Gregorio J., Le Roy D., Roger T. et al., 2015. Nature Immunology, 16 (9) pp. 970-979. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8915C0704772]
 
Virological and Immunological Characterization of Novel NYVAC-Based HIV/AIDS Vaccine Candidates Expressing Clade C Trimeric Soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as Virus-Like Particles.
Perdiguero B., Gómez C.E., Cepeda V., Sánchez-Sampedro L., García-Arriaza J., Mejías-Pérez E., Jiménez V., Sánchez C., Sorzano C.Ó., Oliveros J.C. et al., 2015. Journal of Virology, 89 (2) pp. 970-988. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5051C6A40F15]
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.
Ives A., Nomura J., Martinon F., Roger T., LeRoy D., Miner J.N., Simon G., Busso N., So A., 2015. Nature Communications, 6 p. 6555.
[URN][DOI][WoS][Pmid][serval:BIB_2EC23A4A7881]
2014
 
Bivalent NYVAC-based Vaccine Candidates against HIV/AIDS Expressing Clade C Trimeric Soluble gp140(ZM96) and Gag(ZM96)-Pol-Nef(CN54) as VLPs.
Perdiguero B., Gómez C.E., Cepeda M.V., Sánchez-Sampedro L., García-Arriaza J., Mejías-Pérez E., Jiménez V., Sánchez C., Sorzano C.O., Delaloye J. et al., 2014. pp. A119 dans Aids Research and Human Retroviruses. Peer-reviewed.
[DOI][Pmid][serval:BIB_A173C82FBCD3]
Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders.
Perreau M., Vigano S., Bellanger F., Pellaton C., Buss G., Comte D., Roger T., Lacabaratz C., Bart P.A., Levy Y. et al., 2014. Journal of Experimental Medicine, 211 (10) pp. 2033-2045. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4C2E49D53264]
Health risks following wheat dust exposure during agricultural work : focus on Fusarium spp
Vacher Gaëlle, Niculita-Hirzel Hélène, Roger Thierry, 2014. pp. 41-42 dans 3rd International Congress on Environmental Health 2014, Porto, 24th to 26th September 2014 : proceedings book, Porto : ESTSP-IPP.
[URN][serval:BIB_88721E24328E]
2013
Deletion of the Vaccinia Virus Gene A46R, Encoding for an Inhibitor of TLR Signalling, Is an Effective Approach to Enhance the Immunogenicity in Mice of the HIV/AIDS Vaccine Candidate NYVAC-C.
Perdiguero B., Gómez C.E., Di Pilato M., Sorzano C.O., Delaloye J., Roger T., Calandra T., Pantaleo G., Esteban M., 2013. Plos One, 8 (9) pp. e74831. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E338A0FB5AA2]
 
Epigenetics in sepsis: targeting histone deacetylases.
Ciarlo E., Savva A., Roger T., 2013. International Journal of Antimicrobial Agents, 42 (Suppl.) pp. S8-S12.
[DOI][WoS][Pmid][serval:BIB_681D67C12F26]
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Balamurugan K., Sharan S., Klarmann K.D., Zhang Y., Coppola V., Summers G.H., Roger T., Morrison D.K., Keller J.R., Sterneck E., 2013. Nature Communications, 4 p. 1662.
[URN][DOI][WoS][Pmid][serval:BIB_74C4B858B27D]
IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction.
Bibert S., Roger T., Calandra T., Bochud M., Cerny A., Semmo N., Duong F.H., Gerlach T., Malinverni R., Moradpour D. et al., 2013. Journal of Experimental Medicine, 210 (6) pp. 1109-1116. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6445CEECC43D]
 
IL28B Rna Expression Depends On A Novel Tt/-G Polymorphism Associated With Improved Hcv Clearance Prediction
Bibert S., Roger T., Calandra T., Bochud M., Cerny A., Semmo N., Duong F.H., Gerlach T., Malinverni R., Moradpour D. et al., 2013. pp. S571 dans Abstracts of The International Liver Congress 2013 - 48th Annual Meeting of the European Association for the Study of the Liver, Journal of Hepatology.
[DOI][WoS][serval:BIB_9DBE632C4182]
 
Lack of Mycobacterium tuberculosis-specific interleukin-17A-producing CD4(+) T cells in active disease.
Perreau M., Rozot V., Welles H.C., Belluti-Enders F., Vigano S., Maillard M., Dorta G., Mazza-Stalder Jesica, Bart P.A., Roger T. et al., 2013. European Journal of Immunology, 43 (4) pp. 939-948.
[DOI][WoS][Pmid][serval:BIB_E956D462F256]
Macrophage Migration Inhibitory Factor Deficiency Is Associated With Impaired Killing of Gram-Negative Bacteria by Macrophages and Increased Susceptibility to Klebsiella pneumoniae Sepsis.
Roger T., Delaloye J., Chanson A.L., Giddey M., Le Roy D., Calandra T., 2013. Journal of Infectious Diseases, 207 (2) pp. 331-339.
[URN][DOI][WoS][Pmid][serval:BIB_128D1C9ED56C]
 
Pancreatic stone protein as a novel marker for neonatal sepsis.
Schlapbach L.J., Graf R., Woerner A., Fontana M., Zimmermann-Baer U., Glauser D., Giannoni E., Roger T., Müller C., Nelle M. et al., 2013. Intensive Care Medicine, 39 (4) pp. 754-763.
[DOI][WoS][Pmid][serval:BIB_5694EF7D83D0]
 
Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.
Tawadros T., Alonso F., Jichlinski P., Clarke N., Calandra T., Haefliger J.A., Roger T., 2013. Endocrine-Related Cancer, 20 (1) pp. 137-149.
[DOI][WoS][Pmid][serval:BIB_4EBA811E0FF4]
Targeting Toll-Like Receptors: Promising Therapeutic Strategies for the Management of Sepsis-Associated Pathology and Infectious Diseases.
Savva A., Roger T., 2013. Frontiers in Immunology, 4 p. 387. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F8A91FB09BA8]
 
The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock.
Lugrin J., Ciarlo E., Santos A., Grandmaison G., dos Santos I., Le Roy D., Roger T., 2013. Biochimica et Biophysica Acta, 1833 (6) pp. 1498-1510.
[DOI][WoS][Pmid][serval:BIB_0F6F53429C86]
 
Use of a human-like low-grade bacteremia model of experimental endocarditis to study the role of Staphylococcus aureus adhesins and platelet aggregation in early endocarditis.
Veloso T.R., Chaouch A., Roger T., Giddey M., Vouillamoz J., Majcherczyk P., Que Y.A., Rousson V., Moreillon P., Entenza J.M., 2013. Infection and Immunity, 81 (3) pp. 697-703. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_055F07556E9F]
2012
 
A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease.
Renner Pascal, Roger Thierry, Bochud Pierre-Yves, Sprong Tom, Sweep Fred C.G.J., Bochud Murielle, Faust Saul N., Haralambous Elene, Betts Helen, Chanson Anne-Laure et al., 2012. Faseb Journal, 26 (2) pp. 907-916. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F5DFBCC583E6]
Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.
Perdiguero B., Gómez C.E., Nájera J.L., Sorzano C.O., Delaloye J., González-Sanz R., Jiménez V., Roger T., Calandra T., Pantaleo G. et al., 2012. Plos One, 7 (10) pp. e48524. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CA881424A3B7]
 
Epigenetic control of MIF expression
Roger T., Lugrin J., Ding X.C., Calandra T., 2012. pp. 121-128 dans Bucala R. (eds.) The MIF Handbook, World Scientific Publishing.
[serval:BIB_5A841BFF79D2]
Hepatitis B Virus e Antigen Physically Associates With Receptor-Interacting Serine/Threonine Protein Kinase 2 and Regulates IL-6 Gene Expression.
Wu S., Kanda T., Imazeki F., Nakamoto S., Tanaka T., Arai M., Roger T., Shirasawa H., Nomura F., Yokosuka O., 2012. Journal of Infectious Diseases, 206 (3) pp. 415-420.
[URN][DOI][WoS][Pmid][serval:BIB_98603AB7AD12]
 
Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection.
Delaloye J., De Bruin I.J., Darling K.E., Reymond M.K., Sweep F.C., Roger T., Calandra T., Cavassini M., 2012. Cytokine, 60 (2) pp. 338-340. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E4B458967B9E]
 
Macrophage migration inhibitory factor is involved in a positive feedback loop increasing aromatase expression in endometriosis.
Veillat V., Sengers V., Metz C.N., Roger T., Leboeuf M., Mailloux J., Akoum A., 2012. American Journal of Pathology, 181 (3) pp. 917-927. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_87ADFD6D82E4]
 
Modulation of human memory T-cell function by different antigen-presenting cells.
Perreau M., Welles H.C., Harari A., Calandra T., Roger T., Pantaleo G., 2012. European Journal of Immunology, 42 (3) pp. 799-802.
[DOI][WoS][Pmid][serval:BIB_426696050FC2]
 
Neutralization of Macrophage Migration Inhibitory Factor (MIF) by Fully Human Antibodies Correlates with Their Specificity for the β-Sheet Structure of MIF.
Kerschbaumer R.J., Rieger M., Völkel D., Le Roy D., Roger T., Garbaraviciene J., Boehncke W.H., Müllberg J., Hoet R.M., Wood C.R. et al., 2012. Journal of Biological Chemistry, 287 (10) pp. 7446-7455.
[DOI][WoS][Pmid][serval:BIB_73FC2C8192D5]
Species-Specific Recognition of Aspergillus fumigatus by Toll-like Receptor 1 and Toll-like Receptor 6.
Rubino I., Coste A., Le Roy D., Roger T., Jaton K., Boeckh M., Monod M., Latgé J.P., Calandra T., Bochud P.Y., 2012. Journal of Infectious Diseases, 205 (6) pp. 944-954. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5B3E6BB03173]
Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.
Gómez C.E., Perdiguero B., Jiménez V., Filali-Mouhim A., Ghneim K., Haddad E.K., Quakkelaar E.D., Quakkerlaar E.D., Delaloye J., Harari A. et al., 2012. Plos One, 7 (4) pp. e35485.
[URN][DOI][WoS][Pmid][serval:BIB_C791C445724A]
The glucocorticoid-induced leucine zipper (gilz/tsc22d3-2) gene locus plays a crucial role in male fertility.
Suarez P.E., Rodriguez E.G., Soundararajan R., Mérillat A.M., Stehle J.C., Rotman S., Roger T., Voirol M.J., Wang J., Gross O. et al., 2012. Molecular Endocrinology, 26 (6) pp. 1000-1013.
[URN][DOI][WoS][Pmid][serval:BIB_413D486D499A]
2011
A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses.
García-Arriaza J., Nájera J.L., Gómez C.E., Tewabe N., Sorzano C.O., Calandra T., Roger T., Esteban M., 2011. Plos One, 6 (8) pp. e24244.
[URN][DOI][WoS][Pmid][serval:BIB_B0A1E2688D7A]
 
A Candidate HIV/AIDS Vaccine (MVA-B) that Enhances the Magnitude and Polyfunctionality of Memory HIV-1-Specific T-Cell Responses
Garcia-Arriaza J., Najera J., Gomez C.E., Tewabe N., Sorzano C.S., Calandra T., Roger T., Esteban M., 2011. pp. A108-A109 dans AIDS Vaccine 2011 Conference, Aids Research and Human Retroviruses. Peer-reviewed.
[WoS][serval:BIB_E38DE33A0E89]
 
Basic calcium phosphate crystals induce monocyte/macrophage IL-1(beta) secretion through the NLRP3 inflammasome in vitro.
Pazár B., Ea H.K., Narayan S., Kolly L., Bagnoud N., Chobaz V., Roger T., Lioté F., So A., Busso N., 2011. Journal of Immunology, 186 (4) pp. 2495-2502.
[DOI][WoS][Pmid][serval:BIB_5814AFB917ED]
 
Biliverdin inhibits Toll-like receptor-4 (TLR4) expression through nitric oxide-dependent nuclear translocation of biliverdin reductase.
Wegiel B., Gallo D., Csizmadia E., Roger T., Kaczmarek E., Harris C., Zuckerbraun B.S., Otterbein L.E., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (46) pp. 18849-18854. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_517302667305]
 
Estradiol and progesterone strongly inhibit the innate immune response of mononuclear cells in newborns.
Giannoni E., Guignard L., Knaup Reymond M., Perreau M., Roth-Kleiner M., Calandra T., Roger T., 2011. Infection and Immunity, 79 (7) pp. 2690-2698.
[DOI][WoS][Pmid][serval:BIB_6802E9F344A6]
 
Growth arrest-specific gene 6 (GAS6) as an intra-hospital mortality predictor for patients in septic shock
Stalder G., Kosinski C., Delodder F., Ternon B., Roger T., Calandra T., Duchosal M.A., Eggimann P., Angelillo-Scherrer A., 2011. p. 14 dans ISTH 2011, 23rd Congress of the International Society on Thrombosis and Haemostasis, 57th Annual SSC Meeting (Scientific and Standardization Committee), Journal of Thrombosis and Haemostasis. Peer-reviewed.
[WoS][serval:BIB_61DF0559A106]
Hepatitis C Virus Nonstructural 5A Protein Inhibits Lipopolysaccharide-Mediated Apoptosis of Hepatocytes by Decreasing Expression of Toll-Like Receptor 4.
Tamura R., Kanda T., Imazeki F., Wu S., Nakamoto S., Tanaka T., Arai M., Fujiwara K., Saito K., Roger T. et al., 2011. Journal of Infectious Diseases, 204 (5) pp. 793-801.
[URN][DOI][WoS][Pmid][serval:BIB_8D7AA67EB4A2]
Histone deacetylase inhibitors impair antibacterial defenses of macrophages.
Mombelli M., Lugrin J., Rubino I., Chanson A.L., Giddey M., Calandra T., Roger T., 2011. Journal of Infectious Diseases, 204 (9) pp. 1367-1374.
[URN][DOI][WoS][Pmid][serval:BIB_B919DFAC5DBD]
 
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection.
Roger T., Lugrin J., Le Roy D., Goy G., Mombelli M., Koessler T., Ding X.C., Chanson A.L., Reymond M.K., Miconnet I. et al., 2011. Blood, 117 (4) pp. 1205-1217.
[DOI][WoS][Pmid][serval:BIB_9A8960742F27]
 
Impact of Pre-Existing Immunity on the Selection of Rare Adenovirus Vector Candidates: Implications for HIV Vaccine Development
Perreau M., Welles H.C., Harari A., Potin L., Martin R., Bibert S., Roger T., Calandra T., Bett A., Gall J. et al., 2011. pp. A109 dans AIDS Vaccine 2011 Conference, Aids Research and Human Retroviruses. Peer-reviewed.
[WoS][serval:BIB_52448710FD7A]
 
Malignant lymphoma cells induce tolerance of T cells
Hilmenyuk T., Roger T., Calandra T., Ruepp M. D., Ochsenbein A. F., 2011. p. 90 dans Annual Congress SGAI-SSAI, Advances in immunology and allergology: from research to diagnosis and therapy, Allergologie. Peer-reviewed.
[WoS][serval:BIB_C0A30C6A5F0A]
 
Umbilical venous concentrations of estradiol in infants with early-onset neonatal sepsis and chorioamnionitis.
Schlapbach L.G., Frey S., Roger T., Calandra T., Nelle M., Aebi C., Giannoni E., 2011. Journal of Neonatal-Perinatal Medicine, 4 (2) pp. 147-154. Peer-reviewed.
[DOI][serval:BIB_7283A5E3529E]
2010
 
Role of MyD88 and Toll-like receptors 2 and 4 in the sensing of Parachlamydia acanthamoebae.
Roger T., Casson N., Croxatto A., Entenza J.M., Pusztaszeri M., Akira S., Reymond M.K., Le Roy D., Calandra T., Greub G., 2010/12. Infection and immunity, 78 (12) pp. 5195-5201. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C3E61D584C70]
 
Adiponectin and heme oxygenase-1 suppress TLR4/MyD88-independent signaling in rat Kupffer cells and in mice after chronic ethanol exposure.
Mandal P., Roychowdhury S., Park P.H., Pratt B.T., Roger T., Nagy L.E., 2010. Journal of Immunology, 185 (8) pp. 4928-4937.
[DOI][WoS][Pmid][serval:BIB_ED8549D63D2F]
Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.
Wiersinga W. Joost , Calandra Thierry, Kager Liesbeth M., van der Windt Gerritje J.W., Roger Thierry, le Roy Didier, Florquin Sandrine, Peacock Sharon J., Sweep Fred C.G.J., van der Poll Tom, 2010. Plos Neglected Tropical Diseases, 4 (2) p. 605.
[URN][DOI][WoS][Pmid][serval:BIB_DD36723B235A]
 
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action.
Ouertatani-Sakouhi H., El-Turk F., Fauvet B., Cho M.K., Pinar Karpinar D., Le Roy D., Dewor M., Roger T., Bernhagen J., Calandra T. et al., 2010. Journal of Biological Chemistry, 285 (34) pp. 26581-26598.
[DOI][WoS][Pmid][serval:BIB_C6DDF1D68B64]
 
Interleukin-33 safeguards neutrophils in sepsis.
Roger Thierry, Calandra Thierry, 2010. Nature Medicine, 16 (6) pp. 638-639.
[DOI][WoS][Pmid][serval:BIB_03B9897D1A3D]
 
Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice.
Serre-Beinier V., Toso C., Morel P., Gonelle-Gispert C., Veyrat-Durebex C., Rohner-Jeanrenaud F., Calandra T., Roger T., James R.W., Montet X. et al., 2010. Journal of Endocrinology, 206 (3) pp. 297-306.
[DOI][WoS][Pmid][serval:BIB_9176461B94ED]
 
Phenotypical Characterization of GILZ-Deficient Mice.
Suarez P. E., Rodriguez E. Gonzalez , Stehle J. C., Rotman S., Wang J., Soundararajan R., Gross O., Petrilli V., Wilson A., Roger T. et al., 2010. pp. - dans 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), Endocrine Reviews. Peer-reviewed.
[WoS][serval:BIB_0BE523C3169A]
 
Possible roles of gonadotropins in endometriosis
Akoum A., Bourcier N., Rao CV., Metz C., Roger T., Al-Akoum M., 2010. pp. 208-215 dans Kumar A., Rao C.V., Chaturvedi P.K., Halder A., Rahman N. (eds.) Gonadal and Nongonadal Actions of Gonadotropins, Narosa.
[serval:BIB_A36BCB41CF18]
2009
 
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.
Roger T., Froidevaux C., Le Roy D., Reymond M.K., Chanson A.L., Mauri D., Burns K., Riederer B.M., Akira S., Calandra T., 2009/02. Proceedings of the National Academy of Sciences of the United States of America, 106 (7) pp. 2348-2352. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7916D743A3A0]
A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.
Ouertatani-Sakouhi H., El-Turk F., Fauvet B., Roger T., Le Roy D., Karpinar D.P., Leng L., Bucala R., Zweckstetter M., Calandra T. et al., 2009. Biochemistry, 48 (41) pp. 9858-9870. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BE829752AEE3]
Glucocorticoid-induced MIF expression by human CEM T cells.
Leng Lin, Wang Wenkui, Roger Thierry, Merk Melanie, Wuttke Martina, Calandra Thierry, Bucala Richard, 2009. Cytokine, 48 (3) pp. 177-185. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DB9CCAFA5DD3]
 
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation.
Lugrin J., Ding X.C., Le Roy D., Chanson A.L., Sweep F.C., Calandra T., Roger T., 2009. Biochimica et Biophysica Acta-Molecular Cell Research, 1793 (11) pp. 1749-1758. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67828ECF621D]
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.
Delaloye J., Roger T., Steiner-Tardivel Q.G., Le Roy D., Knaup Reymond M., Akira S., Petrilli V., Gomez C.E., Perdiguero B., Tschopp J. et al., 2009. PLoS Pathogens, 5 (6) pp. e1000480.
[URN][DOI][WoS][Pmid][serval:BIB_C705291364B8]
 
Involvement of nuclear factor-kappaB in macrophage migration inhibitory factor gene transcription up-regulation induced by interleukin- 1 beta in ectopic endometrial cells.
Veillat V., Lavoie C.H., Metz C.N., Roger T., Labelle Y., Akoum A., 2009. Fertility and Sterility, 91 (5 Suppl) pp. 2148-2156.
[DOI][WoS][Pmid][serval:BIB_2859A3D6F4E4]
 
The dexamethasone-induced inhibition of proliferation, migration, and invasion in glioma cell lines is antagonized by macrophage migration inhibitory factor (MIF) and can be enhanced by specific MIF inhibitors.
Piette C., Deprez M., Roger T., Noël A., Foidart J.M., Munaut C., 2009. Journal of Biological Chemistry, 284 (47) pp. 32483-32492.
[DOI][WoS][Pmid][serval:BIB_7F24F5DD7ECB]
 
TLR2-mediated neutrophil depletion exacerbates bacterial sepsis.
Roger T., Calandra T., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (17) pp. 6889-6890.
[DOI][WoS][Pmid][serval:BIB_87229D9BE033]
2008
 
Gas6 and its receptors are implicated in sepsis as modulators of innate immunity
Burnier Laurent, Sugamele Rocco, Le Roy Didier, Roger Thierry, Fumeaux Thierry, Chanson Marc, Borgel Delphine, Lemke Greg, Matsushima Glenn K., Earp Shelton et al., 2008., American Society of Hematology pp. 711A-711A dans 49th Annual Meeting of the American Society of Hematology, Blood. Peer-reviewed.
[WoS][serval:BIB_0AB3075124E1]
 
Growth Arrest-Specific Gene 6 product modulates innate immunity in sepsis
Burnier L., Sugamele R., Leroy D., Roger T., Fumeaux T., Clauser S., Chanson M., Rignault S., Carmeliet P., Pugin J. et al., 2008. p. 43 dans 42nd Annual Scientific Meeting of the European Society for Clinical Investigation, European Journal of Clinical Investigation. Peer-reviewed.
[WoS][serval:BIB_8AC3405959F3]
 
Inhibitors of histone deacetylases impair innate immune responses of macrophages : P215
Mombelli M., Francois P., Giddey M., Reymond M.K., Lugrin J., Schrenzel J., Calandra T., Roger T., 2008. pp. 49S-50S dans Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery, Swiss Medical Weekly. Peer-reviewed.
[WoS][serval:BIB_8F2C57277CB6]
 
Innate immune responses of macrophages and dendritic cells to poxvirus : P199
Delaloye J., Roger T., Esteban M., Steiner-Tardivel Q., Calandra T., 2008. pp. 46S dans Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery, Swiss Medical Weekly. Peer-reviewed.
[WoS][serval:BIB_D4D3F0146A8C]
 
The inhibitor of histone deacetylases (HDI) trichostatin A (TSA) down-regulates macrophage migration inhibitory factor (MIF) gene expression through a local deacetylation of the MIF promoter
Roger T., Ding X., Lugrin J., Le Poy D., Chanson A.L., Calandra T., 2008. pp. 49S dans Annual Joint Meeting of the Swiss Societies for Pneumology, Paediatric Pneumology, Allergology and Immunology, Thoracic Surgery, Swiss Medical Weekly. Peer-reviewed.
[WoS][serval:BIB_FB1DF694BD9F]
 
The role of macrophage migration inhibitory factor in mouse islet transplantation.
Toso C., Serre-Beinier V., Emamaullee J., Merani S., Armanet M., Wojtusciszyn A., Bosco D., Calandra T., Roger T., Morel P. et al., 2008. Transplantation, 86 (10) pp. 1361-1369. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D9FDD47F8FEA]
2007
 
Regulation of human lung adenocarcinoma cell migration and invasion by macrophage migration inhibitory factor.
Rendon B.E., Roger T., Teneng I., Zhao M., Al-Abed Y., Calandra T., Mitchell R.A., 2007/10. Journal of Biological Chemistry, 282 (41) pp. 29910-29918. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_181C58A0779E]
 
Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.
Bondeva T., Roger T., Wolf G., 2007. American Journal of Nephrology, 27 (3) pp. 308-314.
[DOI][WoS][Pmid][serval:BIB_1F5837DADABB]
 
MIF in innate immunity and infectious diseases
Kaech C., Roger T., Calandra T. , 2007. p. 3 dans Bucala R. (eds.) MIF: a most interesting factor, World Scientific Publishing Co.
[serval:BIB_9D44D212E386]
 
Regulation of constitutive and microbial pathogen-induced human macrophage migration inhibitory factor (MIF) gene expression.
Roger T., Ding X., Chanson A.L., Renner P., Calandra T., 2007. European Journal of Immunology, 37 (12) pp. 3509-3521. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_05823E3002EA]
2006
 
Histone acetyltransferase HBO1 inhibits NF-kappaB activity by coactivator sequestration
Contzler R., Regamey A., Favre B., Roger T., Hohl D., Huber M., 2006/11. Biochemical and Biophysical Research Communications, 350 (1) pp. 208-13.
[DOI][WoS][Pmid][serval:BIB_D8925C4B9B42]
 
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity
Lue H., Kapurniotu A., Fingerle-Rowson G., Roger T., Leng L., Thiele M., Calandra T., Bucala R., Bernhagen J., 2006/05. Cellular Signalling, 18 (5) pp. 688-703.
[DOI][WoS][Pmid][serval:BIB_34EA77FC28E0]
 
Angiotensin II upregulates toll-like receptor 4 on mesangial cells.
Wolf G., Bohlender J., Bondeva T., Roger T., Thaiss F., Wenzel U.O., 2006. Journal of the American Society of Nephrology : Jasn, 17 (6) pp. 1585-1593.
[DOI][WoS][Pmid][serval:BIB_37AB51EADBB3]
 
Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1.
Tsatsanis C., Androulidaki A., Alissafi T., Charalampopoulos I., Dermitzaki E., Roger T., Gravanis A., Margioris A.N., 2006. Journal of Immunology, 176 (3) pp. 1869-1877.
[WoS][Pmid][serval:BIB_74C8564C5583]
Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB.
Cao W.G., Morin M., Sengers V., Metz C., Roger T., Maheux R., Akoum A., 2006. Human Reproduction (oxford, England), 21 (2) pp. 421-428.
[URN][DOI][WoS][Pmid][serval:BIB_138741830708]
2005
 
Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1
Roger T., Chanson A. L., Knaup-Reymond M., Calandra T., 2005/12. European Journal of Immunology, 35 (12) pp. 3405-13.
[DOI][WoS][Pmid][serval:BIB_D7B5E76087E9]
Macrophage migration inhibitory factor: gene polymorphisms and susceptibility to inflammatory diseases
Renner P., Roger T., Calandra T., 2005/11. Clinical Infectious Diseases, 41 Suppl 7 pp. S513-9.
[URN][DOI][WoS][Pmid][serval:BIB_5A232E2AFB66]
 
Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression.
Roger T., Miconnet I., Schiesser A.L., Kai H., Miyake K., Calandra T., 2005. The Biochemical journal, 387 (Pt 2) pp. 355-65.
[DOI][WoS][Pmid][serval:BIB_B353B81B94B3]
2004
 
Exaggerated IL-8 and IL-6 responses to TNF-alpha by parainfluenza virus type 4-infected NCI-H292 cells.
Roger T., Bresser P., Snoek M., van der Sluijs K., van den Berg A., Nijhuis M., Jansen H.M., Lutter R., 2004/11. American Journal of Physiology. Lung Cellular and Molecular Physiology, 287 (5) pp. L1048-1055. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4C07CF5FF419]
2003
The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor
Regamey A., Hohl D., Liu J. W., Roger T., Kogerman P., Toftgard R., Huber M., 2003/12. Journal of Experimental Medicine, 198 (12) pp. 1959-64.
[URN][DOI][WoS][Pmid][serval:BIB_1D52738E52B5]
 
Mechanisms that potentially underlie virus-induced exaggerated inflammatory responses by airway epithelial cells
Lutter R., van Wissen M., Roger T., Bresser P., van der Sluijs K., Nijhuis M., Jansen H. M., 2003/03. Chest, 123 (3 Suppl) pp. 391S-2S.
[DOI][WoS][Pmid][serval:BIB_FE88BB589B11]
 
Macrophage migration inhibitory factor (MIF) regulates host responses to endotoxin through modulation of Toll-like receptor 4 (TLR4).
Roger T., Froidevaux C., Martin C., Calandra T., 2003. Journal of Endotoxin Research, 9 (2) pp. 119-123. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FB1FD57C4BD3]
Macrophage migration inhibitory factor and host innate immune defenses against bacterial sepsis.
Calandra T., Froidevaux C., Martin C., Roger T., 2003. The Journal of infectious diseases, 187 Suppl 2 pp. S385-90. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_19D02A04C9E2]
Macrophage migration inhibitory factor: a regulator of innate immunity.
Calandra T., Roger T., 2003. Nature reviews. Immunology, 3 (10) pp. 791-800. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2CA3902B3091]
2002
 
Initial responses to endotoxins and Gram-negative bacteria
Heumann D., Roger T., 2002/09. Clinica Chimica Acta, 323 (1-2) pp. 59-72.
[DOI][WoS][Pmid][serval:BIB_1BAA41567071]
 
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
Lue H., Kleemann R., Calandra T., Roger T., Bernhagen J., 2002/04. Microbes and Infection, 4 (4) pp. 449-60.
[DOI][WoS][Pmid][serval:BIB_69373A259847]
2001
 
MIF regulates innate immune responses through modulation of Toll-like receptor 4
Roger T., David J., Glauser M. P., Calandra T., 2001/12. Nature, 414 (6866) pp. 920-4.
[DOI][WoS][Pmid][serval:BIB_B388FA9C2E51]
 
Macrophage migration inhibitory factor and innate immune responses to bacterial infections
Froidevaux C., Roger T., Martin C., Glauser M. P., Calandra T., 2001/07. Critical Care Medicine, 29 (7 Suppl) pp. S13-5.
[DOI][WoS][Pmid][serval:BIB_08F503AF60AE]
 
Macrophage migration inhibitory (MIF): a pro-inflammatory mediator of sepsis
Martin C., Roger T., Calandra T., 2001. pp. 45-67 dans Eichaker P.Q., Pugin J. (eds.) Evolving concepts in sepsis and sepsis shock, Kluwer Academic Publishers.
[serval:BIB_E595B225EF4D]
 
Macrophage migration inhibitory factor (MIF) modulates innate immune responses induced by endotoxin and Gram-negative bacteria
Roger T., Glauser M. P., Calandra T., 2001. Journal of Endotoxin Research, 7 (6) pp. 456-60.
[WoS][Pmid][serval:BIB_B92F6EE5F331]
2000
 
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
Kleemann R., Hausser A., Geiger G., Mischke R., Burger-Kentischer A., Flieger O., Johannes F. J., Roger T., Calandra T., Kapurniotu A. et al., 2000/11. Nature, 408 (6809) pp. 211-6.
[DOI][WoS][Pmid][serval:BIB_7A0C6CAC86B2]
 
IL-6 protein production by airway epithelial(-like) cells disabled in IL-6 mRNA degradation
Lutter R., Loman S., Snoek M., Roger T., Out T. A., Jansen H. M., 2000/08. Cytokine, 12 (8) pp. 1275-9.
[DOI][WoS][Pmid][serval:BIB_C2F497F455D7]
1998
 
Superinduction of interleukin-6 mRNA in lung epithelial H292 cells depends on transiently increased C/EBP activity and durable increased mRNA stability
Roger T., Out T. A., Jansen H. M., Lutter R., 1998/07. Biochimica et Biophysica Acta-Gene Structure and Expression, 1398 (3) pp. 275-84. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_011337FF9BCC]
 
Enhanced AP-1 and NF-kappaB activities and stability of interleukin 8 (IL-8) transcripts are implicated in IL-8 mRNA superinduction in lung epithelial H292 cells
Roger T., Out T., Mukaida N., Matsushima K., Jansen H., Lutter R., 1998/02. Biochemical Journal, 330 (1) pp. 429-435.
[WoS][Pmid][serval:BIB_F6185CFD417F]
1996
 
Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes
Roger T., Morisset J., Seman M., 1996. Immunogenetics, 43 (3) pp. 165-6.
[WoS][Pmid][serval:BIB_773CDB940535]
1995
 
Critical role of endogenous Mtv in acute lethal graft-versus-host disease
Miconnet I., Roger T., Seman M., Bruley-Rosset M., 1995/02. European Journal of Immunology, 25 (2) pp. 364-8.
[DOI][WoS][Pmid][serval:BIB_8A695FC9BE3F]
1994
 
Coding sequence polymorphism of Tcrg-V1, -V2, and -V4 genes in mice bearing Tcr-gA and -gC haplotypes
Roger T., Miconnet I., Bruley-Rosset M., Seman M., 1994. Immunogenetics, 39 (1) pp. 68-70.
[WoS][Pmid][serval:BIB_C771B6D080E4]
 
Etude de la différenciation des lymphocytes T
Roger T. Boudaly S., 1994. Biopédago, 15 pp. 28-45.
[serval:BIB_A594DDE2D035]
 
Etude des propriétés physiologiques des lymphocytes T et des lymphocytes B murins
Boudaly S. Roger T., 1994. Biopédago, 15 pp. 12-27.
[serval:BIB_A60950925B8F]
 
Negative segregation of Mtv loci in H-2E+ mice selected for high antibody response
Roger T., Boudaly S., Seman M., 1994. Immunogenetics, 40 (2) pp. 123-8.
[WoS][Pmid][serval:BIB_4DCDCDC9607C]
1993
 
Mls-1 and Mls-2 superantigens do not control susceptibility to collagen-induced arthritis in HI and HII mice
Roger T., Boudaly S., Couderc J., Seman M., 1993/12. Immunology, 80 (4) pp. 661-3.
[WoS][Pmid][serval:BIB_1CE5CE7A1CB6]
 
Rearrangement by chromosomal inversion in the T cell receptor gamma locus in a murine alpha beta T cell clone
Roger T., Miconnet I., Bruley-Rosset M., Seman M., 1993/12. Molecular Immunology, 30 (17) pp. 1617-20.
[DOI][WoS][Pmid][serval:BIB_658C6B6415D2]
 
Preferential V delta 1 expression among TcR gamma/delta-bearing T cells in human oral epithelium
Pepin L. F., Roger T., Morisset J., Seman M., 1993/03. Scandinavian Journal of Immunology, 37 (3) pp. 289-94.
[DOI][WoS][Pmid][serval:BIB_3269012DECA2]
 
Comparison of the repertoire of T-cell lines and clones specific for minor histocompatibility antigens derived from immunized mice and from mice developing a graft-versus-host reaction
Bruley-Rosset M., Miconnet I., Roger T., Seman M., Halle-Pannenko O., 1993/02. Transplantation Proceedings, 25 (1 Pt 1) pp. 94-5.
[WoS][Pmid][serval:BIB_3F670551A2F0]
 
Co-selection of the rare T cell receptor-gamma B haplotype in mouse lines selected for low responsiveness to red blood cell antigens
Roger T., Pepin L. F., Couderc J., De Franco M., Seman M., 1993/01. European Journal of Immunology, 23 (1) pp. 287-90.
[DOI][WoS][Pmid][serval:BIB_016EDF9E13D8]
 
New T-cell receptor gamma haplotypes in wild mice and evidence for limited Tcrg-V gene polymorphism
Roger T., Pepin L. F., Jouvin-Marche E., Cazenave P. A., Seman M., 1993. Immunogenetics, 37 (3) pp. 161-9.
[WoS][Pmid][serval:BIB_179002E0A170]
1992
 
Polymorphism of the Tcrg-V1-V2 region in mice: identification of a new Vg1 allele in DBA/2
Roger T., Seman M., 1992. Immunogenetics, 36 (1) pp. 67-9.
[DOI][WoS][Pmid][serval:BIB_37FA2CC05886]
1991
 
Resistance to collagen-induced arthritis in Biozzi mice is not associated with T cell receptor V beta gene polymorphism
Vidard L., Roger T., Bouvet J. P., Couderc J., Seman M., 1991/07. European Journal of Immunology, 21 (7) pp. 1783-5.
[DOI][WoS][Pmid][serval:BIB_E985C5B02940]
1990
 
Autoreactive T cells in normal mice: unrestricted recognition of self peptides on dendritic cell I-A molecules by CD4-CD8- T cell receptor alpha/beta+ T cell clones expressing V beta 8.1 gene segments
Seman M., Boudaly S., Roger T., Morisset J., Pham G., 1990/06. European Journal of Immunology, 20 (6) pp. 1265-72.
[DOI][WoS][Pmid][serval:BIB_B659314C75FE]
 
Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness
Vidard L., Roger T., Pham G., Couderc J., Bouthillier Y., Mevel J. C., Mouton D., Seman M., 1990. Immunogenetics, 32 (1) pp. 27-33.
[DOI][WoS][Pmid][serval:BIB_088849D78156]
1989
 
Analyse génétique et moléculaire
Roger T., 1989. pp. 87-109 dans Debré P., Seman M. (eds.) Clonage des lymphocytes T, éditions INSERM.
[serval:BIB_DF20A704A609]
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