Marie-Gabrielle Zurich Fontanellaz

Publications | Phd and Masters theses

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61 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2015 | 2014 | 2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1987 | 1986 |
2024
Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.
Chandrasekaran V., Wellens S., Bourguignon A., Djidrovski I., Fransen L., Ghosh S., Mazidi Z., Murphy C., Nunes C., Singh P. et al., 2024/06. Toxicology in vitro, 98 p. 105826. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_17CE74341EA3]
Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility.
Pamies D., Ekert J., Zurich M.G., Frey O., Werner S., Piergiovanni M., Freedman B.S., Keong Teo A.K., Erfurth H., Reyes D.R. et al., 2024/05/14. Stem cell reports, 19 (5) pp. 604-617. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_1C641B815478]
Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments.
Hopf N.B., Suter-Dick L., Huwyler J., Borgatta M., Hegg L., Pamies D., Paschoud H., Puligilla R.D., Reale E., Werner S. et al., 2024/01/18. JMIR research protocols, 13 pp. e50300. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_41A06BB224C8]
2023
Digoxin Induces Human Astrocyte Reaction In Vitro.
Pamies D., Vujić T., Schvartz D., Boccard J., Repond C., Nunes C., Rudaz S., Sanchez J.C., González-Ruiz V., Zurich M.G., 2023/01. Molecular neurobiology, 60 (1) pp. 84-97. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F7961A5E222B]
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone.
Nunes C., Proença S., Ambrosini G., Pamies D., Thomas A., Kramer N.I., Zurich M.G., 2023. Frontiers in pharmacology, 14 p. 1248882. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5026E918AA69]
2022
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
Nunes C., Singh P., Mazidi Z., Murphy C., Bourguignon A., Wellens S., Chandrasekaran V., Ghosh S., Zana M., Pamies D. et al., 2022/06. Toxicology in vitro, 81 p. 105333. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FEAAC77037C3]
2021
 
Human IPSC-Derived Model to Study Myelin Disruption.
Chesnut M., Paschoud H., Repond C., Smirnova L., Hartung T., Zurich M.G., Hogberg H.T., Pamies D., 2021/08/31. International journal of molecular sciences, 22 (17) p. 9473. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_45BEDBE1924C]
 
Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro.
Pamies D., Sartori C., Schvartz D., González-Ruiz V., Pellerin L., Nunes C., Tavel D., Maillard V., Boccard J., Rudaz S. et al., 2021/04/14. International journal of molecular sciences, 22 (8). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E8DC218E471]
2020
 
Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem.
Pamies D., Zurich M.G., Hartung T., 2020/10/23. iScience, 23 (10) p. 101633. Peer-reviewed.
[DOI][Pmid][serval:BIB_3EDD5151369D]
2019
 
Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures.
Schvartz D., González-Ruiz V., Walter N., Antinori P., Jeanneret F., Tonoli D., Boccard J., Zurich M.G., Rudaz S., Monnet-Tschudi F. et al., 2019/10. Toxicology in vitro, 60 pp. 281-292. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_71CF0C89DD43]
 
Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity.
Calderazzo S., Tavel D., Zurich M.G., Kopp-Schneider A., 2019/09. Archives of toxicology, 93 (9) pp. 2635-2644. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F8E7E90B5212]
 
Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity.
Bal-Price A., Hogberg H.T., Crofton K.M., Daneshian M., FitzGerald R.E., Fritsche E., Heinonen T., Hougaard Bennekou S., Klima S., Piersma A.H. et al., 2019. ALTEX, 36 (3) p. 506. Peer-reviewed.
[DOI][Pmid][serval:BIB_EBFAC34BBDB0]
2018
 
Longitudinal investigation of the metabolome of 3D aggregating brain cell cultures at different maturation stages by <sup>1</sup>H HR-MAS NMR.
Diserens G., Vermathen M., Zurich M.G., Vermathen P., 2018/10. Analytical and bioanalytical chemistry, 410 (26) pp. 6733-6749. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9CD73DA5A938]
 
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Bal-Price A., Hogberg H.T., Crofton K.M., Daneshian M., FitzGerald R.E., Fritsche E., Heinonen T., Hougaard Bennekou S., Klima S., Piersma A.H. et al., 2018. ALTEX, 35 (3) pp. 306-352. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_866FEC6DF239]
2017
 
3D in vitro models for developmental neurotoxicity (DNT)
Stoppini Luc, von Tobel Jenny, Charvet Igor, Zurich Marie-Gabrielle, Sundstom Lars, Maonnet-Tschudi F, 2017/06/26., Wang, C and Slikker, W, Jr.
[serval:BIB_BBC6AEE49B76]
2015
 
Amiodarone biokinetics, the formation of its major oxidative metabolite and neurotoxicity after acute and repeated exposure of brain cell cultures.
Pomponio G., Zurich M.G., Schultz L., Weiss D.G., Romanelli L., Gramowski-Voss A., Di Consiglio E., Testai E., 2015. Toxicology In Vitro : An International Journal Published In Association With Bibra, 30 (1 Pt A) pp. 192-202. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EBB6D8809FA2]
Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures.
Vichi S., Sandström von Tobel J., Gemma S., Stanzel S., Kopp-Schneider A., Monnet-Tschudi F., Testai E., Zurich M.G., 2015. Toxicology In Vitro : An International Journal Published In Association With Bibra, 30 (1 Pt A) pp. 176-184. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A6C4F3AA22F9]
 
Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood-brain barrier.
Bellwon P., Culot M., Wilmes A., Schmidt T., Zurich M.G., Schultz L., Schmal O., Gramowski-Voss A., Weiss D.G., Jennings P. et al., 2015. Toxicology In Vitro : An International Journal Published In Association With Bibra, 30 (1 Pt A) pp. 166-175. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7942021B330D]
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
Schultz L., Zurich M.G., Culot M., da Costa A., Landry C., Bellwon P., Kristl T., Hörmann K., Ruzek S., Aiche S. et al., 2015. Toxicology In Vitro : An International Journal Published In Association With Bibra, 30 (1 Pt A) pp. 138-165. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9B8DF2911C50]
 
The in vitro biokinetics of chlorpromazine and diazepam in aggregating rat brain cell cultures after repeated exposure.
Broeders J.J., Hermens J.L., Blaauboer B.J., Zurich M.G., 2015. Toxicology In Vitro, 30 (1 Pt A) pp. 185-191. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1CD7D37A6F02]
2014
 
Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype.
von Tobel J.S., Antinori P., Zurich M.G., Rosset R., Aschner M., Glück F., Scherl A., Monnet-Tschudi F., 2014. Neurotoxicology, 44 pp. 61-70. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9537E43E3E52]
State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.
Alépée N., Bahinski A., Daneshian M., De Wever B., Fritsche E., Goldberg A., Hansmann J., Hartung T., Haycock J., Hogberg H. et al., 2014. Altex, 31 (4) pp. 441-477. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9EA7D2F80BEE]
2013
 
Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity.
Zurich M.G., Stanzel S., Kopp-Schneider A., Prieto P., Honegger P., 2013. Toxicology in Vitro, 27 (4) pp. 1416-1424. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_283C4C88FCBB]
Stochastic time-concentration activity models for cytotoxicity in 3D brain cell cultures.
Renner M., Zurich M.G., Kopp-Schneider A., 2013. Theoretical Biology and Medical Modelling, 10 p. 19.
[URN][DOI][WoS][Pmid][serval:BIB_1C9FA7FAAB0D]
 
The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox.
Prieto P., Kinsner-Ovaskainen A., Stanzel S., Albella B., Artursson P., Campillo N., Cecchelli R., Cerrato L., Díaz L., Di Consiglio E. et al., 2013. Toxicology in Vitro, 27 (4) pp. 1357-1376.
[DOI][WoS][Pmid][serval:BIB_1549CBC633C4]
2011
 
Methods to assess neuroinflammation.
Monnet-Tschudi F., Defaux A., Braissant O., Cagnon L., Zurich M.G., 2011. pp. Unit12.19 dans Current protocols in Toxicology chap. 12, Wiley.
[DOI][Pmid][serval:BIB_6DD0BF1E70AC]
 
Minocycline promotes remyelination in aggregating rat brain cell cultures after interferon-γ plus lipopolysaccharide-induced demyelination.
Defaux A., Zurich M.G., Honegger P., Monnet-Tschudi F., 2011. Neuroscience, 187 pp. 84-92.
[DOI][WoS][Pmid][serval:BIB_BC1F95F80AB9]
 
Ochratoxin A at nanomolar concentration perturbs the homeostasis of neural stem cells in highly differentiated but not in immature three-dimensional brain cell cultures.
Zurich M.G., Honegger P., 2011. Toxicology Letters, 205 (2) pp. 203-208.
[DOI][WoS][Pmid][serval:BIB_FB2B373ECF67]
 
Preparation and use of serum-free aggregating brain cell cultures for routine neurotoxicity screening
Honegger P., Zurich. M.-G. , 2011. pp. 105-128 dans Aschner M., Suñol C., Bal-Price A. (eds.) Cell culture techniques chap. 5, Humana Press.
[DOI][serval:BIB_3E876168524E]
 
Preparation, maintenance, and use of serum-free aggregating brain cell cultures.
Honegger P., Defaux A., Monnet-Tschudi F., Zurich M.G., 2011. Methods in Molecular Biology, 758 pp. 81-97.
[DOI][WoS][Pmid][serval:BIB_AB1CFAE11B60]
2010
 
Aggregating brain cell cultures for neurotoxicity tests.
Honegger P., Monnet-Tschudi F., Zurich M.G., 2010. pp. 41-60 dans Maguire T., Novik E. (eds.) Alternative technologies to animal testing chap. 3, Artech House.
[serval:BIB_7131E16A11AA]
 
Inflammatory responses in aggregating rat brain cell cultures subjected to different demyelinating conditions.
Defaux A., Zurich M.G., Honegger P., Monnet-Tschudi F., 2010. Brain Research, 1353 pp. 213-224.
[DOI][WoS][Pmid][serval:BIB_50F1DC1455BD]
 
Probable involvement of heavy metal-induced neuroinflammation in neurodegeneration.
Monnet-Tschudi F., Defaux A., Zurich M.G., 2010. pp. 1-13 dans Metals and Neurodegeneration, Huang S..
[serval:BIB_954D4A0B9D54]
2009
 
Contribution of in vitro neurotoxicology studies to the elucidation of neurodegenerative processes.
Zurich M.G., Monnet-Tschudi F., 2009. Brain Research Bulletin, 80 (4-5) pp. 211-216.
[DOI][WoS][Pmid][serval:BIB_88160209025E]
Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination.
Defaux A., Zurich M.G., Braissant O., Honegger P., Monnet-Tschudi F., 2009. Journal of Neuroinflammation, 6 p. 15.
[URN][DOI][WoS][Pmid][serval:BIB_A74CAED83BA4]
 
Neuronal in vitro models for the estimation of acute systemic toxicity.
Forsby A., Bal-Price A.K., Camins A., Coecke S., Fabre N., Gustafsson H., Honegger P., Kinsner-Ovaskainen A., Pallas M., Rimbau V. et al., 2009. Toxicology in Vitro, 23 (8) pp. 1564-1569.
[DOI][WoS][Pmid][serval:BIB_48DC6DF28660]
2008
 
Delta-9-tetrahydrocannabinol accumulation, metabolism and cell-type-specific adverse effects in aggregating brain cell cultures.
Monnet-Tschudi F., Hazekamp A., Perret N., Zurich M.G., Mangin P., Giroud C., Honegger P., 2008. Toxicology and Applied Pharmacology, 228 (1) pp. 8-16.
[DOI][WoS][Pmid][serval:BIB_392FC4D85CA2]
2007
 
Neurotoxicant-induced inflammatory response in three-dimensional brain cell cultures.
Monnet-Tschudi F., Zurich M.G., Honegger P., 2007/04. Human and Experimental Toxicology, 26 (4) pp. 339-346.
[DOI][WoS][Pmid][serval:BIB_6CBE69625C7B]
2006
 
Involvement of environmental mercury and lead in the etiology of neurodegenerative diseases.
Monnet-Tschudi F., Zurich M.G., Boschat C., Corbaz A., Honegger P., 2006/06. Reviews on Environmental Health, 21 (2) pp. 105-117.
[Pmid][serval:BIB_2B9A43D58900]
2005
 
Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures.
Zurich M.G., Lengacher S., Braissant O., Monnet-Tschudi F., Pellerin L., Honegger P., 2005. Neuroscience, 134 (3) pp. 771-782.
[DOI][WoS][Pmid][serval:BIB_35682]
2004
 
Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos.
Zurich M.G., Honegger P., Schilter B., Costa L.G., Monnet-Tschudi F., 2004/12. Toxicology and Applied Pharmacology, 201 (2) pp. 97-104.
[DOI][WoS][Pmid][serval:BIB_759E42496F83]
 
Aggregating brain cell cultures for neurotoxicological studies.
Zurich M.G., Monnet-Tschudi F., Costa L.G., Schilter B., Honegger P., 2004. pp. 243-266 dans Tiffany-Castiglioni E. (eds.) In vitro neurotoxicology : principles and challenges, Humana Press.
[DOI][serval:BIB_26853]
 
Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones.
Uldry M., Steiner P., Zurich M.G., Béguin P., Hirling H., Dolci W., Thorens B., 2004. The EMBO Journal, 23 (3) pp. 531-540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88BF8D7B4578]
2003
 
Regulation of peptidase activity in a three-dimensional aggregate model of brain tumor vasculature.
Juillerat-Jeanneret L., Monnet-Tschudi F., Zurich M.G., Lohm S., Duijvestijn A.M., Honegger P., 2003/01. Cell and Tissue Research, 311 (1) pp. 53-59.
[DOI][WoS][Pmid][serval:BIB_C57E6044ACAE]
2002
Ammonium-induced impairment of axonal growth is prevented through glial creatine.
Braissant O., Henry H., Villard A.M., Zurich M.G., Loup M., Eilers B., Parlascino G., Matter E., Boulat O., Honegger P. et al., 2002/11/15. The Journal of neuroscience, 22 (22) pp. 9810-9820. Peer-reviewed.
[URN][WoS][Pmid][serval:BIB_5EC36D0C3C26]
Alteration of amino acid metabolism in neuronal aggregate cultures exposed to hypoglycaemic conditions.
Honegger P., Braissant O., Henry H., Boulat O., Bachmann C., Zurich M.G., Pardo B., 2002/06. Journal of Neurochemistry, 81 (6) pp. 1141-1151.
[URN][DOI][WoS][Pmid][serval:BIB_92DA4F5C8FC8]
 
Maturation-dependent neurotoxicity of lead acetate in vitro: implication of glial reactions.
Zurich M.G., Eskes C., Honegger P., Bérode M., Monnet-Tschudi F., 2002. Journal of Neuroscience Research, 70 (1) pp. 108-116. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_23011]
2000
 
Use of aggregating brain cell cultures to study developmental effects of organophosphorus insecticides.
Zurich M.G., Honegger P., Schilter B., Costa L.G., Monnet-Tschudi F., 2000/08. Neurotoxicology, 21 (4) pp. 599-605.
[WoS][Pmid][serval:BIB_F265CF96D9A2]
 
Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures.
Monnet-Tschudi F., Zurich M.G., Schilter B., Costa L.G., Honegger P., 2000/06. Toxicology and Applied Pharmacology, 165 (3) pp. 175-183.
[DOI][WoS][Pmid][serval:BIB_6EFB7968844C]
1999
 
The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture.
Monnet-Tschudi F., Zurich M.G., Sorg O., Matthieu J.M., Honegger P., Schilter B., 1999/02. Neurotoxicology, 20 (1) pp. 41-48. Peer-reviewed.
[WoS][Pmid][serval:BIB_2B01C2FA42D1]
1998
 
Lead acetate toxicity in vitro: Dependence on the cell composition of the cultures.
Zurich M.G., Monnet-Tschudi F., Bérode M., Honegger P., 1998. Toxicology in Vitro, 12 (2) pp. 191-196. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_644CF6AA2437]
1997
 
Effects of the naturally occurring food mycotoxin ochratoxin A on brain cells in culture.
Monnet-Tschudi F., Sorg O., Honegger P., Zurich M.G., Huggett A.C., Schilter B., 1997. Neurotoxicology, 18 (3) pp. 831-839.
[WoS][Pmid][serval:BIB_075F1E456981]
1996
 
Comparison of the developmental effects of two mercury compounds on glial cells and neurons in aggregate cultures of rat telencephalon.
Monnet-Tschudi F., Zurich M.G., Honegger P., 1996. Brain Research, 741 (1-2) pp. 52-59.
[DOI][WoS][Pmid][serval:BIB_D520144213CE]
1995
 
Microglial responsiveness as a sensitive marker for trimethyltin (TMT) neurotoxicity.
Monnet-Tschudi F., Zurich M.G., Pithon E., van Melle G., Honegger P., 1995/08. Brain Research, 690 (1) pp. 8-14.
[DOI][WoS][Pmid][serval:BIB_B14ABBFC01A6]
 
Effects of trimethyltin (TMT) on glial and neuronal cells in aggregate cultures: dependence on the developmental stage.
Monnet-Tschudi F., Zurich M.G., Riederer B.M., Honegger P., 1995. Neurotoxicology, 16 (1) pp. 97-104.
[WoS][Pmid][serval:BIB_E4F7640C942E]
1994
 
Long-term treatment of aggregating brain cell cultures with low concentrations of lead acetate.
Zurich M.G., Monnet-Tschudi F., Honegger P., 1994. Neurotoxicology, 15 (3) pp. 715-719.
[WoS][Pmid][serval:BIB_9C9F41A9F94D]
1993
 
Evaluation of the toxicity of different metal compounds in the developing brain using aggregating cell cultures as a model.
Monnet-Tschudi F., Zurich M.G., Honegger P., 1993. Toxicology In Vitro, 7 (4) pp. 335-339.
[WoS][Pmid][serval:BIB_C11CA6057B93]
 
Glial hyaluronate-binding protein expression in aggregating brain cell cultures.
Monnet-Tschudi F., Zurich M.G., Asher R., Honegger P., 1993. Developmental Neuroscience, 15 (6) pp. 395-402.
[DOI][WoS][Pmid][serval:BIB_F66F9E05AA18]
 
Improvement of culture conditions for aggregating brain cells to study remyelination.
Zurich M.G., Matthieu J.M., Honegger P., 1993. Schweizer Archiv für Neurologie und Psychiatrie, 144 (3) pp. 228-232.
[Pmid][serval:BIB_B99591788CAC]
1987
 
Influence of sex and age on T3 receptors and T3 concentration in the pituitary gland of the rat: consequences on TSH secretion.
Donda A., Reymond M.J., Zürich M.G., Lemarchand-Béraud T., 1987/11. Molecular and Cellular Endocrinology, 54 (1) pp. 29-34.
[DOI][WoS][Pmid][serval:BIB_5FCB58673101]
1986
 
Dose and time effects of treatment with low doses of a LRH agonist on testicular axis and accessory sex organs in rats.
Lemarchand-Béraud T., Jaussan V., Zürich M.G., 1986. Acta Endocrinologica, 112 (4) pp. 595-602.
[WoS][Pmid][serval:BIB_99BED81ABD4E]
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