Nathalie Busso

Publications | Mémoires et thèses

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106 publications

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A new ex vivo human model of osteoarthritis cartilage calcification.
Faure E., Wegrzyn J., Bernabei I., Falgayrac G., Bertheaume N., Pascart T., Hugle T., Busso N., Nasi S. Rheumatology. Peer-reviewed.
Inhibiting Lysyl Oxidases prevents pathologic cartilage calcification.
Bernabei I., Faure E., Romani M., Wegrzyn J., Brinckmann J., Chobaz V., So A., Hugle T., Busso N., Nasi S., 2024/02. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 171 p. 116075. Peer-reviewed.
 
CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity.
Bernabei I., Hansen U., Ehirchiou D., Brinckmann J., Chobaz V., Busso N., Nasi S., 2023/06/05. International journal of molecular sciences, 24 (11) p. 9776. Peer-reviewed.
 
ITGAM rs1143679 Variant in Systemic Lupus Erythematosus Is Associated with Increased Serum Calcification Propensity.
Halfon M., Zhang L., Ehirchiou D., Pandian V.D., Dahdal S., Huynh-Do U., Pasch A., Ribi C., Busso N., 2023/05/18. Genes, 14 (5) p. 1105. Peer-reviewed.
 
Cartilage calcification in osteoarthritis: mechanisms and clinical relevance.
Bernabei I., So A., Busso N., Nasi S., 2023/01. Nature reviews. Rheumatology, 19 (1) pp. 10-27. Peer-reviewed.
Fibrin deposition associates with cartilage degeneration in arthritis.
Hügle T., Nasi S., Ehirchiou D., Omoumi P., So A., Busso N., 2022/07. EBioMedicine, 81 p. 104081. Peer-reviewed.
The Gasotransmitter Hydrogen Sulfide (H<sub>2</sub>S) Prevents Pathologic Calcification (PC) in Cartilage.
Nasi S., Ehirchiou D., Bertrand J., Castelblanco M., Mitchell J., Ishii I., So A., Busso N., 2021/09/08. Antioxidants, 10 (9) p. 1433. Peer-reviewed.
 
Multi-energy photon-counting computed tomography versus other clinical imaging techniques for the identification of articular calcium crystal deposition.
Bernabei I., Sayous Y., Raja A.Y., Amma M.R., Viry A., Steinmetz S., Falgayrac G., van Heeswijk R.B., Omoumi P., Pascart T. et al., 2021/05/14. Rheumatology, 60 (5) pp. 2483-2485. Peer-reviewed.
Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.
Nasi S., Castelblanco M., Chobaz V., Ehirchiou D., So A., Bernabei I., Kusano T., Nishino T., Okamoto K., Busso N., 2021. Frontiers in cell and developmental biology, 9 p. 612440. Peer-reviewed.
The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H<sub>2</sub>S) pathway against experimental osteoarthritis.
Nasi S., Ehirchiou D., Chatzianastasiou A., Nagahara N., Papapetropoulos A., Bertrand J., Cirino G., So A., Busso N., 2020/03/17. Arthritis research & therapy, 22 (1) p. 49. Peer-reviewed.
 
The role of the gasotransmitter hydrogen sulfide in pathological calcification.
Castelblanco M., Nasi S., Pasch A., So A., Busso N., 2020/02. British journal of pharmacology, 177 (4) pp. 778-792. Peer-reviewed.
CD11b Signaling Prevents Chondrocyte Mineralization and Attenuates the Severity of Osteoarthritis.
Ehirchiou D., Bernabei I., Chobaz V., Castelblanco M., Hügle T., So A., Zhang L., Busso N., Nasi S., 2020. Frontiers in cell and developmental biology, 8 p. 611757. Peer-reviewed.
Increased Prevalence of NLRP3 Q703K Variant Among Patients With Autoinflammatory Diseases: An International Multicentric Study.
Theodoropoulou K., Wittkowski H., Busso N., Von Scheven-Gête A., Moix I., Vanoni F., Hengten V., Horneff G., Haas J.P., Fischer N. et al., 2020. Frontiers in immunology, 11 p. 877. Peer-reviewed.
Febuxostat, a Xanthine Oxidoreductase Inhibitor, Decreases NLRP3-dependent Inflammation in Macrophages by Activating the Purine Salvage Pathway and Restoring Cellular Bioenergetics.
Nomura J., Kobayashi T., So A., Busso N., 2019/11/21. Scientific reports, 9 (1) p. 17314. Peer-reviewed.
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
Kusano T., Ehirchiou D., Matsumura T., Chobaz V., Nasi S., Castelblanco M., So A., Lavanchy C., Acha-Orbea H., Nishino T. et al., 2019/10/28. Nature communications, 10 (1) p. 4904. Peer-reviewed.
 
Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation.
Castelblanco M., Lugrin J., Ehirchiou D., Nasi S., Ishii I., So A., Martinon F., Busso N., 2018/02/16. The Journal of biological chemistry, 293 (7) pp. 2546-2557. Peer-reviewed.
 
CD11b regulates the Treg/Th17 balance in murine arthritis via IL-6.
Stevanin M., Busso N., Chobaz V., Pigni M., Ghassem-Zadeh S., Zhang L., Acha-Orbea H., Ehirchiou D., 2017/04. European journal of immunology, 47 (4) pp. 637-645. Peer-reviewed.
 
Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome.
Cheung M.S., Theodoropoulou K., Lugrin J., Martinon F., Busso N., Hofer M., 2017. Journal of Immunology, 198 (5) pp. 2063-2069. Peer-reviewed.
 
Interleukin-6 and chondrocyte mineralisation act in tandem to promote experimental osteoarthritis.
Nasi S., So A., Combes C., Daudon M., Busso N., 2016/07. Annals of the rheumatic diseases, 75 (7) pp. 1372-1379. Peer-reviewed.
Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis.
Nasi S., Ea H.K., Lioté F., So A., Busso N., 2016. PloS one, 11 (7) pp. e0158196. Peer-reviewed.
Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis.
Grosjean F., Nasi S., Schneider P., Chobaz V., Liu A., Mordasini V., Moullec K., Vezzoni P., Lavanchy C., Busso N. et al., 2015. Plos One, 10 (8) pp. e0133917. Peer-reviewed.
 
Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation.
Nomura J., So A., Tamura M., Busso N., 2015. Journal of Immunology, 195 (12) pp. 5718-5724. Peer-reviewed.
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.
Ives A., Nomura J., Martinon F., Roger T., LeRoy D., Miner J.N., Simon G., Busso N., So A., 2015. Nature Communications, 6 p. 6555.
 
Dispensable role of myeloid differentiation primary response gene 88 (MyD88) and MyD88-dependent toll-like receptors (TLRs) in a murine model of osteoarthritis.
Nasi S., Ea H.K., Chobaz V., van Lent P., Lioté F., So A., Busso N., 2014/07. Joint, Bone, Spine : Revue du Rhumatisme, 81 (4) pp. 320-324.
 
Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.
Holzinger D., Nippe N., Vogl T., Marketon K., Mysore V., Weinhage T., Dalbeth N., Pool B., Merriman T., Baeten D. et al., 2014. Arthritis and Rheumatology, 66 (5) pp. 1327-1339. Peer-reviewed.
 
The concept of the inflammasome and its rheumatologic implications.
So A., Busso N., 2014. Joint, Bone, Spine, 81 (5) pp. 398-402. Peer-reviewed.
Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice.
Nomura J., Busso N., Ives A., Matsui C., Tsujimoto S., Shirakura T., Tamura M., Kobayashi T., So A., Yamanaka Y., 2014. Scientific Reports, 4 p. 4554. Peer-reviewed.
 
Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production.
Kolly L., Busso N., von Scheven-Gete A., Bagnoud N., Moix I., Holzinger D., Simon G., Ives A., Guarda G., So A. et al., 2013/06. The Journal of allergy and clinical immunology, 131 (6) pp. 1635-1643. Peer-reviewed.
Febuxostat, an Inhibitor of Xanthine Oxidase, Suppresses Lipopolysaccharide-Induced MCP-1 Production via MAPK Phosphatase-1-Mediated Inactivation of JNK.
Nomura J., Busso N., Ives A., Tsujimoto S., Tamura M., So A., Yamanaka Y., 2013. Plos One, 8 (9) pp. e75527.
Pathogenic role of basic calcium phosphate crystals in destructive arthropathies.
Ea H.K., Chobaz V., Nguyen C., Nasi S., van Lent P., Daudon M., Dessombz A., Bazin D., McCarthy G., Jolles-Haeberli B. et al., 2013. Plos One, 8 (2) pp. e57352.
Revisiting spatial distribution and biochemical composition of calcium-containing crystals in human osteoarthritic articular cartilage.
Nguyen C., Bazin D., Daudon M., Chatron-Colliet A., Hannouche D., Bianchi A., Côme D., So A., Busso N., Lioté F. et al., 2013. Arthritis Research and Therapy, 15 (5) pp. R103. Peer-reviewed.
 
Targeting inflammasomes in rheumatic diseases.
So A., Ives A., Joosten L.A., Busso N., 2013. Nature Reviews. Rheumatology, 9 (7) pp. 391-399. Peer-reviewed.
Microcrystals as DAMPs and their role in joint inflammation.
Busso N., So A., 2012. Rheumatology (oxford, England), 51 (7) pp. 1154-1160.
 
The mechanisms of inflammation in gout and pseudogout (CPP-induced arthritis).
Busso N., Ea H.K., 2012. Reumatismo, 63 (4) pp. 230-237.
 
Thrombin-sensitive dual fluorescence imaging and therapeutic agent for detection and treatment of synovial inflammation in murine rheumatoid arthritis.
Gabriel D., Lange N., Chobaz-Peclat V., Zuluaga M.F., Gurny R., van den Bergh H., Busso N., 2012. Journal of Controlled Release, 163 (2) pp. 178-186. Peer-reviewed.
 
Update on gout 2012.
So A., Busso N., 2012. Joint, Bone, Spine : Revue du Rhumatisme, 79 (6) pp. 539-543.
 
Octacalcium phosphate crystals induce inflammation in vivo through interleukin-1 but independent of the NLRP3 inflammasome in mice.
Narayan S., Pazar B., Ea H.K., Kolly L., Bagnoud N., Chobaz V., Lioté F., Vogl T., Holzinger D., Kai-Lik So A. et al., 2011/02. Arthritis and rheumatism, 63 (2) pp. 422-433. Peer-reviewed.
 
Basic calcium phosphate crystals induce monocyte/macrophage IL-1(beta) secretion through the NLRP3 inflammasome in vitro.
Pazár B., Ea H.K., Narayan S., Kolly L., Bagnoud N., Chobaz V., Roger T., Lioté F., So A., Busso N., 2011. Journal of Immunology, 186 (4) pp. 2495-2502.
 
Basic calcium phosphate crystals induce NLRP3 inflammasome activation: The in vitro and in vivo face to face.
Ea H.K., So A., Lioté F., Busso N., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (50) pp. E1361.
 
Increased interleukin-10 production by ASC-deficient CD4(+) T cells impairs bystander T-cell proliferation.
Narayan S., Kolly L., So A., Busso N., 2011. Immunology, 134 (1) pp. 33-40.
 
Interleukin-1β activation during acute joint inflammation: A limited role for the NLRP3 inflammasome in vivo.
Joosten L.A., Ea H.K., Netea M.G., Busso N., 2011. Joint, Bone, Spine : Revue du Rhumatisme, 78 (2) pp. 107-110.
 
Osteoarthritis: Crystal-gazing into the pathogenesis of osteoarthritis.
So A., Busso N., 2011. Nature Reviews. Rheumatology, 7 (12) pp. 688-689.
 
PAR2 Promotes Vaccine-Induced Protection Against Helicobacter Infection in Mice.
Velin D., Narayan S., Bernasconi E., Busso N., Ramelli G., Maillard M.H., Bachmann D., Pythoud C., Bouzourene H., Michetti P. et al., 2011. Gastroenterology, 141 (4) pp. 1273-1282.e1.
 
Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints.
Schmitt F., Lagopoulos L., Käuper P., Rossi N., Busso N., Barge J., Wagnières G., Laue C., Wandrey C., Juillerat-Jeanneret L., 2010/06/01. Journal of controlled release, 144 (2) pp. 242-250. Peer-reviewed.
 
Basic calcium phosphate crystals induce IL-1B secretion in vitro through activation of the Nalp3 inflammasome
Pazar B., Busso N., Kolly L., Narayan S., Bagnoud N., Chobaz V., Ea H.O., Lioté F., Yazdi A., Tschopp J. et al., 2010. p. 326 dans EULAR 2010, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Kyste synovial de l'épaule traité par aspiration et infiltration sous échographie : rapport de 3 cas avec pathologies différentes
Pazar B., Faucherre M., Buss G., Rappoport G., Revaz S., Aubry-Rozier B., So A., Zufferey P., 2010. dans SFR 2010, 23e Congrès de la Société Française de Rhumatologie.
Mechanisms of inflammation in gout.
Busso N., So A., 2010. Arthritis Research and Therapy, 12 (2) p. 206.
 
Octacalcium phosphate (OCP) crystals induce IL-1A and IL-1B dependent inflammation in mice
Pazar B., Narayan S., Kolly L., Bagnoud N., Chobaz V., Tschopp J., Ea H.-K., Lioté F., Holzinger D., So A. et al., 2010. p. 667 dans EULAR 2010, Annual European Congress of Rheumatology, Annals of the Rheumatic diseases. Peer-reviewed.
 
Octacalcium Phosphate (OCP) Crystals Induce Synovial Inflammation and Cartilage
Busso N., Chobaz V., Bagnoud N., Van Lent P., Nguyen C., Liote F., So A., 2010. p. 2151 dans American College of Rheumatology/Association of Rheumatology Health Professionals Annual Scientific Meeting, Arthritis and Rheumatism. Peer-reviewed.
 
Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo.
Ramelli G., Fuertes S., Narayan S., Busso N., Acha-Orbea H., So A., 2010. Immunology, 129 (1) pp. 20-27. Peer-reviewed.
 
Role of Protease-activated receptor in vaccine-induced protection against Helicobacter infection
Velin Dominique, Narayan Sharma, Bernasconi Eric, Busso Nathalie, Ramelli Giancarlo, Maillard Michel H., Bachmann Daniel, Pythoud Catherine, Bouzourene Hanifa, Michetti Pierre et al., 2010. pp. 12S dans Annual meeting of the Swiss Society of Gastroenterology, Swiss Society for Visceral, Surgery Swiss Association for the Study of the Liver, Swiss Association of Clinical Nutrition, Swiss Medical Weekly. Peer-reviewed.
 
A magic bullet for gout?
So A., Busso N., 2009. Annals of the Rheumatic Diseases, 68 (10) pp. 1517-1519.
 
Expression and function of the NALP3 inflammasome in rheumatoid synovium.
Kolly L, Busso N, Palmer G, Talabot-Ayer D, Chobaz V, So A, 2009. Immunology, 129 (2) p. 50.
 
Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.
Kolly L., Karababa M., Joosten L.A., Narayan S., Salvi R., Pétrilli V., Tschopp J., van den Berg W.B., So A.K., Busso N., 2009. Journal of Immunology, 183 (6) pp. 4003-4012.
 
Thrombin-sensitive photodynamic agents: a novel strategy for selective synovectomy in rheumatoid arthritis.
Gabriel D., Busso N., So A., van den Bergh H., Gurny R., Lange N., 2009. Journal of Controlled Release, 138 (3) pp. 225-234.
Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation.
Busso N., Chobaz-Péclat V., Hamilton J., Spee P., Wagtmann N., So A., 2008. Arthritis research & Therapy, 10 (2) pp. R42.
 
Implication of dipeptidylpeptidase IV activity in human bronchial inflammation and in bronchoconstriction evaluated in anesthetized rabbits.
Landis B.N., Grouzmann E., Monod M., Busso N., Petak F., Spiliopoulos A., Robert J.H., Szalay-Quinodoz I., Morel D.R., Lacroix J.S., 2008. Respiration, 75 (1) pp. 89-97. Peer-reviewed.
Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD.
Busso Nathalie, Karababa Mahir, Nobile Massimo, Rolaz Aline, Van Gool Frederic, Galli Mara, Leo Oberdan, So Alexander, De Smedt Thibaut, 2008. PloS One, 3 (5) p. 2267. Peer-reviewed.
 
Synovial inflammasome expression in rheumatoid arthritis and osteoarthritis
Kolly L., Chobaz V., So A., Busso N., 2008. p. 595 dans EULAR 2008, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Visfatin/nicotinamide phosphoribosyltransferase (Nampt): Is a novel target for the treatment of inflammatory arthritis
Busso Nathalie, Karababa Mahir, Chobaz Veronique, Nobile Massimo, Rolaz Aline, So Alex, Leo Oberdan, De Smedt Thibaut, 2008. pp. S260-S260 dans 72nd Annual Scientific Meeting of the American College of Rheumatology/43rd Annual Scientific Meeting of the Association of Rheumatology Health-Professionals, Arthritis and Rheumatism. Peer-reviewed.
Expression and function of junctional adhesion molecule-C in human and experimental arthritis
Palmer G., Busso N., Aurrand-Lions M., Talabot-Ayer D., Chobaz-Peclat V., Zimmerli C., Hammel P., Imhof B. A., Gabay C., 2007/07. Arthritis Research and Therapy, 9 (4) pp. R65.
 
Evaluation of protease-activated receptor 2 in murine models of arthritis
Busso N., Frasnelli M., Feifel R., Cenni B., Steinhoff M., Hamilton J., So A., 2007/01. Arthritis and Rheumatism, 56 (1) pp. 101-7.
 
Evaluation of the inflammasome components in murine models of arthritis: critical role of ASC, but not of NALP3
Karababa M., Tschopp J., So A., Busso N., 2007. p. 143 dans EULAR 2007, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/db mice
Palmer G., Aurrand-Lions M., Contassot E., Talabot-Ayer D., Ducrest-Gay D., Vesin C., Chobaz-Peclat V., Busso N., Gabay C., 2006/09. Journal of Immunology, 177 (5) pp. 2899-907.
 
Antibodies against junctional adhesion molecule (JAM)-C decrease the severity of murine antigen-induced arthritis.
Palmer G., Busso N., Talabot-Ayer D., Chobaz-Peclat V., Aurrand-Lions M, Hammel P., Imhof B.A., Gabay C., 2006. p. 136 dans EULAR 2006, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion.
Cavadas C., Céfai D., Rosmaninho-Salgado J., Vieira-Coelho M.A., Moura E., Busso N., Pedrazzini T., Grand D., Rotman S., Waeber B. et al., 2006. Proceedings of the National Academy of Sciences of the United States of America, 103 (27) pp. 10497-10502. Peer-reviewed.
 
Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance
Auge A. P., Longui C. A., Almeida Prado R. A., Rocha M. N., Hirota A., Busso N. E., Monte O., Aldrighi J. M., 2005/07. Gynecological Endocrinology, 21 (1) pp. 7-11.
 
Circulating CD26 is negatively associated with inflammation in human and experimental arthritis
Busso N., Wagtmann N., Herling C., Chobaz-Peclat V., Bischof-Delaloye A., So A., Grouzmann E., 2005/02. American Journal of Pathology, 166 (2) pp. 433-442.
TLR2 modulates inflammation in zymosan-induced arthritis in mice
Frasnelli M. E., Tarussio D., Chobaz-Peclat V., Busso N., So A., 2005. Arthritis Research and Therapy, 7 (2) pp. R370-9.
 
Up-modulation of tissue factor procoagulant activity in culture medium of inflammatory monocytes and endothelial cells and its relevance for rheumatoid arthritis
Mociran M, Busso N., Chobaz-Péclat V., So A., 2005. p. 133 dans EULAR 2005, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Assessment of the efficacy of different statins in murine collagen-induced arthritis
Palmer G., Chobaz V., Talabot-Ayer D., Taylor S., So A., Gabay C., Busso N., 2004/12. Arthritis and Rheumatism, 50 (12) pp. 4051-9.
 
Role of the tissue factor pathway in synovial inflammation
Busso N., Morard C., Salvi R., Peclat V., So A., 2003/03. Arthritis and Rheumatism, 48 (3) pp. 651-9.
 
Arthritis is linked to local and systemic activation of coagulation and fibrinolysis pathways.
So A.K., Varisco P.A., Kemkes-Matthes B., Herkenne-Morard C., Chobaz-Péclat V., Gerster J.C., Busso N., 2003. Journal of thrombosis and haemostasis : JTH, 1 (12) pp. 2510-5. Peer-reviewed.
 
Circulating CD26 is negatively associated with inflammation in rheumatoid arthritis
Busso N, Wagtmann N., Herkenne-Morard C., Cobaz V., Grouzman E., So A., 2003. p. 137 dans EULAR 2003, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Zymosan induced arthritis in mice is biphasic and acts through the TLR2 pathway
Le Roy D., So A., Busso N., Tarussio D., Chobaz V., 2003. p. 138 dans EULAR 2003, Annual European Congress of Rheumatology, Annals of the Rheumatic Diseases. Peer-reviewed.
 
Extravascular coagulation and the plasminogen activator/plasmin system in rheumatoid arthritis
Busso N., Hamilton J. A., 2002/09. Arthritis and Rheumatism, 46 (9) pp. 2268-79.
PPARgamma expression in normal human placenta, hydatidiform mole and choriocarcinoma
Capparuccia L., Marzioni D., Giordano A., Fazioli F., De Nictolis M., Busso N., Todros T., Castellucci M., 2002/06. Molecular Human Reproduction, 8 (6) pp. 574-9.
 
Protoporphyrin IX photodynamic therapy for synovitis
Kirdaite G., Lange N., Busso N., Van Den Bergh H., Kucera P., So A., 2002/05. Arthritis and Rheumatism, 46 (5) pp. 1371-8.
 
Plasminogen activator inhibitor type-1 deficiency attenuates murine antigen-induced arthritis
Van Ness K., Chobaz-Peclat V., Castellucci M., So A., Busso N., 2002/02. Rheumatology, 41 (2) pp. 136-41.
 
Coagulation and fibrinolysis in rheumatic diseases : link with inflammation
Varisco P.A., Morard C., Gerster J.C., Chobaz V., So A., Busso N., 2002. dans Annual Congress of the Swiss Society of Rheumatology.
 
Expression of protease-activated receptors in arthritic synovial tissues
So A.K., Chobas-Péclat C., Morard A., Busso N., 2002. p. 40 dans 22nd European Workshop for Rheumatology Research, Arthritis Research and Therapy. Peer-reviewed.
 
Increased plasma markers of fibrin formation and dissolution in rheumatoid arthritis
Varisco P.A., Morard C., Gerster J.C., Chobaz V., So A.K., Busso N., 2002. dans Annual Congress of the Swiss Society of Rheumatology.
 
Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis
Busso N., So A., Chobaz-Peclat V., Morard C., Martinez-Soria E., Talabot-Ayer D., Gabay C., 2002/01. Journal of Immunology, 168 (2) pp. 875-82.
 
Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice
Robson M. G., Cook H. T., Botto M., Taylor P. R., Busso N., Salvi R., Pusey C. D., Walport M. J., Davies K. A., 2001/06. Journal of Immunology, 166 (11) pp. 6820-8.
 
Amelioration of collagen-induced arthritis by thrombin inhibition
Marty I., Peclat V., Kirdaite G., Salvi R., So A., Busso N., 2001/03. Journal of Clinical Investigation, 107 (5) pp. 631-40.
 
Plasma apolipoprotein(a) co-deposits with fibrin in inflammatory arthritic joints.
Busso N., Dudler J., Salvi R., Péclat V., Lenain V., Marcovina S., Darioli R., Nicod P., So A.K., Mooser V., 2001. American Journal of Pathology, 159 (4) pp. 1445-1453. Peer-reviewed.
 
Effect of thrombin inhibition on synovial inflammation in antigen induced arthritis
Varisco P. A., Peclat V., van Ness K., Bischof-Delaloye A., So A., Busso N., 2000/10. Annals of the Rheumatic Diseases, 59 (10) pp. 781-7.
 
Effect of interleukin 17 on proteoglycan degradation in murine knee joints
Dudler J., Renggli-Zulliger N., Busso N., Lotz M., So A., 2000/07. Annals of the Rheumatic Diseases, 59 (7) pp. 529-32.
 
Enhanced expression of genes involved in coagulation and fibrinolysis in murine arthritis
Salvi R., Peclat V., So A., Busso N., 2000. Arthritis Research, 2 (6) pp. 504-12.
 
Exacerbation of antigen-induced arthritis in urokinase-deficient mice
Busso N., Peclat V., Van Ness K., Kolodziesczyk E., Degen J., Bugge T., So A., 1998/07. Journal of Clinical Investigation, 102 (1) pp. 41-50.
 
Fibrin deposition in the synovium of patients with rheumatoid arthritis, reactive arthritis and osteoarthritis
Busso N., Peclat V., Bos R., Tak P.P., Kolodziesczyk E., So A., 1998. pp. S320 dans 62nd National Scientific Meeting of the American College of Rheumatology, 33rd National Scientific Meeting of the Association of Rheumatology Health Professionals, Arthritis and Rheumatism. Peer-reviewed.
 
Urokinase in rheumatoid arthritis: causal or coincidental?
Busso N., So A., 1997/12. Annals of the Rheumatic Diseases, 56 (12) pp. 705-6.
 
Plasminogen activation in synovial tissues: differences between normal, osteoarthritis, and rheumatoid arthritis joints
Busso N., Peclat V., So A., Sappino A. P., 1997/09. Annals of the Rheumatic Diseases, 56 (9) pp. 550-7.
 
Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells
Busso N., Masur S. K., Lazega D., Waxman S., Ossowski L., 1994/07. Journal of Cell Biology, 126 (1) pp. 259-70.
 
Urokinase and type I plasminogen activator inhibitor production by normal human hepatocytes: modulation by inflammatory agents
Busso N., Nicodeme E., Chesne C., Guillouzo A., Belin D., Hyafil F., 1994/07. Hepatology, 20 (1 Pt 1) pp. 186-90.
 
Down-regulation of retinoic acid receptor activity associated with decreased alpha and gamma isoforms expression in F9 embryonal carcinoma cells differentiated by retinoic acid
Lazega D., Schenker E., Busso N., Zelent A., Chen A., Waxman S., 1993/10. Journal of Cellular Physiology, 157 (1) pp. 90-6.
 
Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: binding, internalization, degradation, and biological effects
Bikfalvi A., Sauzeau C., Moukadiri H., Maclouf J., Busso N., Bryckaert M., Plouet J., Tobelem G., 1991/10. Journal of Cellular Physiology, 149 (1) pp. 50-9.
 
Refractory period phenomenon in the induction of tissue factor expression on endothelial cells
Busso N., Huet S., Nicodeme E., Hiernaux J., Hyafil F., 1991/10. Blood, 78 (8) pp. 2027-35.
 
mRNA for tissue-type plasminogen activator is present in lesional epidermis from patients with psoriasis, pemphigus, or bullous pemphigoid, but is not detected in normal epidermis
Baird J., Lazarus G. S., Belin D., Vassalli J. D., Busso N., Gubler P., Jensen P. J., 1990/11. Journal of Investigative Dermatology, 95 (5) pp. 548-52.
 
Tissue plasminogen activator in psoriasis
Jensen P. J., Baird J., Belin D., Vassalli J. D., Busso N., Gubler P., Lazarus G. S., 1990/11. Journal of Investigative Dermatology, 95 (5) pp. 13S-14S.
 
Transforming growth-factor-beta (TGF-beta) inhibits albumin synthesis in normal human hepatocytes and in hepatoma HepG2 cells
Busso N., Chesne C., Delers F., Morel F., Guillouzo A., 1990/09. Biochemical and Biophysical Research Communications, 171 (2) pp. 647-54.
 
Plasminogen activators in the mouse mammary gland. Decreased expression during lactation.
Busso N., Huarte J., Vassalli J.D., Sappino A.P., Belin D., 1989/05. Journal of Biological Chemistry, 264 (13) pp. 7455-7457. Peer-reviewed.
 
Antagonist effect of RU 486 on transcription of glucocorticoid-regulated genes
Busso N., Collart M., Vassalli J. D., Belin D., 1987/12. Experimental Cell Research, 173 (2) pp. 425-30.
 
Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas
Sappino A. P., Busso N., Belin D., Vassalli J. D., 1987/08. Cancer Research, 47 (15) pp. 4043-6.
 
Glucocorticoid modulation of plasminogen activators and of one of their inhibitors in the human mammary carcinoma cell line MDA-MB-231
Busso N., Belin D., Failly-Crepin C., Vassalli J. D., 1987/01. Cancer Research, 47 (2) pp. 364-70.
 
Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids.
Busso N., Belin D., Failly-Crépin C., Vassalli J.D., 1986/07. Journal of Biological Chemistry, 261 (20) pp. 9309-9315. Peer-reviewed.
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