Lorenz Hirt

Publications | Mémoires et thèses

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112 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1994 | 1991 |
 
Neurologie: ce qui a changé en 2023 [Neurology: what's new in 2023]
Pizzarotti B., Buhler-Heintze A., Allali G., Rouaud O., Bally J., Michel P., Hirt L., Théaudin M., Pot Kreis C., Ryvlin P. et al., 2024/01/17. Revue medicale suisse, 20 (856-7) pp. 72-75. Peer-reviewed.
 
Influence of DNP Polarizing Agents on Biochemical Processes: TEMPOL in Transient Ischemic Stroke.
Lê T.P., Buscemi L., Lepore M., Mishkovsky M., Hyacinthe J.N., Hirt L., 2023/09/06. ACS chemical neuroscience, 14 (17) pp. 3013-3018. Peer-reviewed.
 
Neurologie : ce qui a changé en 2022 [Neurology: what's new in 2022]
Bouvy C., Caranzano L., Allali G., Bally J., Benninger D., Beuchat I., Castro Jimenez M., Di Virgilio G., Hirt L., Michel P. et al., 2023/01/18. Revue medicale suisse, 19 (809-10) pp. 42-45. Peer-reviewed.
Intima-Media Thickness and Pulsatility Index of Common Carotid Arteries in Acute Ischaemic Stroke Patients with Diabetes Mellitus.
Bill O., Mazya M.V., Michel P., Prazeres Moreira T., Lambrou D., Meyer I.A., Hirt L., 2022/12/29. Journal of clinical medicine, 12 (1) p. 246. Peer-reviewed.
Carotid plaque surface echogenicity predicts cerebrovascular events: An Echographic Multicentric Swiss Study.
Sztajzel R.F., Engelter S.T., Bonati L.H., Mono M.L., Slezak A., Kurmann R., Nedeltchev K., Gensicke H., Traenka C., Baumgartner R.W. et al., 2022/11. Journal of neuroimaging, 32 (6) pp. 1142-1152. Peer-reviewed.
Lactate Neuroprotection against Transient Ischemic Brain Injury in Mice Appears Independent of HCAR1 Activation.
Buscemi L., Price M., Castillo-González J., Chatton J.Y., Hirt L., 2022/05/21. Metabolites, 12 (5) p. 465. Peer-reviewed.
Neurologie [Neurology : what's new in 2021]
Vicino A., Allali G., Bally J., Castro Jimenez M., Chiabotti Salvioni P., Hirt L., Hottinger A., Michel P., Novy J., Pot Kreis C. et al., 2022/01/19. Revue medicale suisse, 18 (764-5) pp. 51-55. Peer-reviewed.
Preconditioning by Preceding Ischemic Cerebrovascular Events.
Correia P.N., Meyer I.A., Eskandari A., Amiguet M., Hirt L., Michel P., 2021/08/17. Journal of the American Heart Association, 10 (16) pp. e020129. Peer-reviewed.
Covid-19 et AVC: associés ou non ? [COVID-19 and stroke: associated or not ?]
Michel P., Hirt L., Strambo D., 2021/04/28. Revue medicale suisse, 17 (736) pp. 816-821. Peer-reviewed.
Neurologie [Recent Advances in Neurology]
Anichini A., Salvioni Chiabotti P., Bally J., Castro Jimenez M., Démonet J.F., Di Virgilio G., Hirt L., Hottinger A., Kuntzer T., Michel P. et al., 2021/01/27. Revue medicale suisse, 17 (723) pp. 196-200. Peer-reviewed.
Hydroxycarboxylic Acid Receptor 1 and Neuroprotection in a Mouse Model of Cerebral Ischemia-Reperfusion.
Buscemi L., Blochet C., Magistretti P.J., Hirt L., 2021. Frontiers in physiology, 12 p. 689239. Peer-reviewed.
Predictors of the pulsatility index in the middle cerebral artery of acute stroke patients
Bill Olivier, Lambrou Dimitris, Sotomayor Guillermo Toledo, Meyer Ivo, Michel Patrik, Moreira Tiago, Niederhauser Julien, Hirt Lorenz, 2020/12. Scientific Reports, 10 (1) p. 17110.
Evaluating the potential of hyperpolarised [1-13C] L-lactate as a neuroprotectant metabolic biosensor for stroke.
Hyacinthe J.N., Buscemi L., Lê T.P., Lepore M., Hirt L., Mishkovsky M., 2020/03/26. Scientific reports, 10 (1) p. 5507. Peer-reviewed.
Neurologie [Neurology 2019]
Perrenoud M., Pantazou V., Michel P., Hirt L., Ryvlin P., Theaudin M., Rouaud O., Benninger D., Novy J., Rossetti A.O. et al., 2020/01/15. Revue medicale suisse, 16 (676-7) pp. 68-71. Peer-reviewed.
Caveolin-1 Regulates Perivascular Aquaporin-4 Expression After Cerebral Ischemia.
Filchenko I., Blochet C., Buscemi L., Price M., Badaut J., Hirt L., 2020. Frontiers in cell and developmental biology, 8 p. 371. Peer-reviewed.
Extended preclinical investigation of lactate for neuroprotection after ischemic stroke
Buscemi Lara, Blochet Camille, Price Melanie, Magistretti Pierre J, Lei Hongxia, Hirt Lorenz, 2020/01/01. Clinical and Translational Neuroscience, 4 (1) pp. 2514183X2090457.
Involvement of caveolin-1 in neurovascular unit remodeling after stroke: Effects on neovascularization and astrogliosis.
Blochet C., Buscemi L., Clément T., Gehri S., Badaut J., Hirt L., 2020/01. Journal of cerebral blood flow and metabolism, 40 (1) pp. 163-176. Peer-reviewed.
 
Metabolic fingerprints discriminating severity of acute ischemia using in vivo high-field <sup>1</sup> H magnetic resonance spectroscopy.
Lepore M.G., Buscemi L., Hirt L., Lei H., 2020/01. Journal of neurochemistry, 152 (2) pp. 252-262. Peer-reviewed.
Spatio-temporal overview of neuroinflammation in an experimental mouse stroke model.
Buscemi L., Price M., Bezzi P., Hirt L., 2019/01/24. Scientific reports, 9 (1) p. 507. Peer-reviewed.
 
Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury.
Carteron L., Solari D., Patet C., Quintard H., Miroz J.P., Bloch J., Daniel R.T., Hirt L., Eckert P., Magistretti P.J. et al., 2018/10. Critical care medicine, 46 (10) pp. 1649-1655. Peer-reviewed.
 
Increase of aquaporin 9 expression in astrocytes participates in astrogliosis.
Hirt L., Price M., Mastour N., Brunet J.F., Barrière G., Friscourt F., Badaut J., 2018/02. Journal of neuroscience research, 96 (2) pp. 194-206. Peer-reviewed.
 
Neurologie [Neurology]
Chopard I., Benninger D., Demonet J.F., Du Pasquier R., Hirt L., Kuntzer T., Michel P., Nater B., Novy J., Rossetti A. et al., 2018/01/10. Revue medicale suisse, 14 (588-589) pp. 58-61. Peer-reviewed.
Aquaporins in neurological disorders
Hirt Lorenz, Price Melanie, Benakis Corinne, Badaut Jérôme, 2018/01. Clinical and Translational Neuroscience, 2 (1) pp. 2514183X1775290. Peer-reviewed.
 
Antiagrégation plaquettaire en prévention secondaire de l’AVC ischémique [Antiplatelet therapy in secondary stroke prevention]
Hirt L., Carrera E., 2017/04/26. Revue medicale suisse, 13 (560) pp. 907-910. Peer-reviewed.
 
Organisation de la prise en charge des accidents vasculaires cérébraux en Suisse romande
Carrera E., Hirt L., Sztajzel R., Michel P., Kleinschmidt A., Du Pasquier R., 2017/04/26. Revue medicale suisse, 13 (560) pp. 883-884. Peer-reviewed.
 
Prévention de l’AVC chez les patients avec une fibrillation auriculaire [Stroke prevention in patients with atrial fibrillation]
Sirimarco G., Hirt L., Sztajzel R., Perren F., 2017/04/26. Revue medicale suisse, 13 (560) pp. 911-915. Peer-reviewed.
 
Homer1 Scaffold Proteins Govern Ca2+ Dynamics in Normal and Reactive Astrocytes.
Buscemi L., Ginet V., Lopatar J., Montana V., Pucci L., Spagnuolo P., Zehnder T., Grubišic V., Truttman A., Sala C. et al., 2017/03/01. Cerebral cortex (New York, N.Y. : 1991), 27 (3) pp. 2365-2384. Peer-reviewed.
 
Neurologie [Neurology]
Maulucci F., Benninger D., Démonet J.F., Du Pasquier R.A., Hirt L., Hottinger A., Kuntzer T., Michel P., Nater B., Novy J. et al., 2017/01/11. Revue medicale suisse, 13 (544-545) pp. 79-83. Peer-reviewed.
 
Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice.
Hirt L., Fukuda A.M., Ambadipudi K., Rashid F., Binder D., Verkman A., Ashwal S., Obenaus A., Badaut J., 2017/01. Journal of cerebral blood flow and metabolism, 37 (1) pp. 277-290. Peer-reviewed.
 
Stroke management organization in French-speaking Switzerland,Organisation de la prise en charge des accidents vasculaires cérébraux en Suisse romande
Carrera Emmanuel, Hirt Lorenz, Sztajzel Roman, Michel Patrik, Kleinschmidt Andreas, Du Pasquier Renaud, 2017. Revue Medicale Suisse.
Sympathetic activity and early mobilization in patients in intensive and intermediate care with severe brain injuries: a preliminary prospective randomized study.
Rocca A., Pignat J.M., Berney L., Jöhr J., Van de Ville D., Daniel R.T., Levivier M., Hirt L., Luft A.R., Grouzmann E. et al., 2016/09/13. BMC neurology, 16 p. 169. Peer-reviewed.
Cell-specific modulation of monocarboxylate transporter expression contributes to the metabolic reprograming taking place following cerebral ischemia.
Rosafio K., Castillo X., Hirt L., Pellerin L., 2016/03/11. Neuroscience, 317 pp. 108-120. Peer-reviewed.
 
Predictors of Stroke, Myocardial Infarction or Death within 30 Days of Carotid Artery Stenting: Results from the International Carotid Stenting Study.
Doig D., Turner E.L., Dobson J., Featherstone R.L., Lo R.T., Gaines P.A., Macdonald S., Bonati L.H., Clifton A., Brown M.M. et al., 2016/03. European journal of vascular and endovascular surgery, 51 (3) pp. 327-334. Peer-reviewed.
 
Neurologie [Neurology].
Sokolov A.A., Rossetti A.O., Michel P., Benninger D., Nater B., Wider C., Hirt L., Kuntzer T., Démonet J.F., Du Pasquier R.A. et al., 2016. Revue Médicale Suisse, 12 (500) pp. 62, 64-62, 66.
A probable dual mode of action for both L- and D-lactate neuroprotection in cerebral ischemia.
Castillo X., Rosafio K., Wyss M.T., Drandarov K., Buck A., Pellerin L., Weber B., Hirt L., 2015/10. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35 (10) pp. 1561-1569. Peer-reviewed.
 
Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial.
Bonati L.H., Dobson J., Featherstone R.L., Ederle J., van der Worp H.B., de Borst G.J., Mali W.P., Beard J.D., Cleveland T., Engelter S.T. et al., 2015/02/07. Lancet, 385 (9967) pp. 529-538. Peer-reviewed.
 
Artérite de Horton: recommandations Lausannoises de prise en charge [Giant cell arteritis: guidelines of the University Hospital of Lausanne].
Tsetsou S., Michel P., Ribi C., Hirt L., Kawasaki A., Hugli O., De Leval L., Bart P.A., Waeber G., Meuli R. et al., 2015/02. Revue Médicale Suisse, 11 (461) pp. 411-417.
 
ESOC-1476: Ischaemic preconditioning by recent TIAs and strokes in 2,730 consecutive stroke patients.
Correia P., Meyer IA, Eskandari A., Amiguet M., Hirt L., Michel P., 2015. p. 203 dans International Journal of Stroke.
 
Neurologie [News in neuroloey 2014].
Tsetsou S., Rossetti A.O., Michel P., Hirt L., Wider C., Benninger D., Kuntzer T., Nater B., Démonet J.F., Schluep M. et al., 2015. Revue Médicale Suisse, 11 (456-457) pp. 91-96.
 
Strokes and TIAs during and after Carotid Artery Doppler: Cause or Coincidence?
Papavasileiou V., Milionis H., Hirt L., Michel P., 2015. Ultrasound in Medicine and Biology, 41 (2) pp. 418-422. Peer-reviewed.
Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia.
Berthet C., Xin L., Buscemi L., Benakis C., Gruetter R., Hirt L., Lei H., 2014/11. Journal of Cerebral Blood Flow and Metabolism, 34 (11) pp. 1848-1855. Peer-reviewed.
 
Periprocedural Hemodynamic Depression Is Associated With a Higher Number of New Ischemic Brain Lesions After Stenting in the International Carotid Stenting Study-MRI Substudy.
Altinbas A., Algra A., Bonati L.H., Brown M.M., Kappelle L.J., de Borst G.J., Hendrikse J., van der Tweel I., van der Worp H.B., ICSS Investigators, 2014. Stroke, 45 (1) pp. 146-151. Peer-reviewed.
 
Thromboxane prostaglandin receptor antagonist and carotid atherosclerosis progression in patients with cerebrovascular disease of ischemic origin: a randomized controlled trial.
Bots M.L., Ford I., Lloyd S.M., Laurent S., Touboul P.J., Hennerici M.G., Prevention of Cerebrovascular, Cardiovascular Events of Ischemic Origin With Terutroban in Patients With a History of Ischemic Stroke or Transient Ischemic Attack Vascular Ultrasound Study Investigators, 2014. Stroke, 45 (8) pp. 2348-2353. Peer-reviewed.
 
Effect of white-matter lesions on the risk of periprocedural stroke after carotid artery stenting versus endarterectomy in the International Carotid Stenting Study (ICSS): a prespecified analysis of data from a randomised trial.
Ederle J., Davagnanam I., van der Worp H.B., Venables G.S., Lyrer P.A., Featherstone R.L., Brown M.M., Jäger H.R., ICSS investigators, 2013. Lancet Neurology, 12 (9) pp. 866-872. Peer-reviewed.
Endogenous protease nexin-1 protects against cerebral ischemia.
Mirante O., Price M., Puentes W., Castillo X., Benakis C., Thevenet J., Monard D., Hirt L., 2013. International Journal of Molecular Sciences, 14 (8) pp. 16719-16731. Peer-reviewed.
 
Prise en charge des sténoses carotidiennes [Management of the carotid artery stenosis].
Déglise S., Dubuis C., Mosimann P., Saucy F., Engelberger S., Hirt L., Michel P., Corpataux J.M., 2013. Revue Médicale Suisse, 9 (391) pp. 1305-1311.
 
The effect of continuous positive airway pressure on total cerebral blood flow in healthy awake volunteers.
Yiallourou T.I., Odier C., Heinzer R., Hirt L., Martin B.A., Stergiopulos N., Haba-Rubio J., 2013. Sleep and Breathing = Schlaf and Atmung, 17 (1) pp. 289-296. Peer-reviewed.
 
Early mobilization out of bed after ischaemic stroke reduces severe complications but not cerebral blood flow: a randomized controlled pilot trial.
Diserens Karin, Moreira Tiago, Hirt Lorenz, Faouzi Mohamed, Grujic Jelena, Bieler Gilles, Vuadens Philippe, Michel Patrik, 2012. Clinical Rehabilitation, 26 (5) pp. 451-459. Peer-reviewed.
 
High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice.
Alf M.F., Lei H., Berthet C., Hirt L., Gruetter R., Mlynarik V., 2012. NMR in Biomedicine, 25 (2) pp. 247-254. Peer-reviewed.
 
Neurologie [Neurology].
Chabwine J.N., Rossetti A.R., Hirt L., Kuntzer T., Schluep M., Michel P., Démonet J.F., du Pasquier R.A., Vingerhoets F.G., 2012. Revue Médicale Suisse, 8 (323) pp. 46-50. Peer-reviewed.
Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion.
Benakis C., Vaslin A., Pasquali C., Hirt L., 2012. Journal of Neuroinflammation, 9 p. 76. Peer-reviewed.
 
New evidence of neuroprotection by lactate after transient focal cerebral ischaemia: extended benefit after intracerebroventricular injection and efficacy of intravenous administration.
Berthet C., Castillo X., Magistretti P.J., Hirt L., 2012. Cerebrovascular Diseases, 34 (5-6) pp. 329-335. Peer-reviewed.
 
Risk factor impact on blood flow velocities and clinical outcomes of stented cervical and intracranial stenoses: preliminary observations.
Moreira T., Michel P., Binaghi S., Hirt L., 2012. Clinical Neurology and Neurosurgery, 114 (7) pp. 922-929. Peer-reviewed.
 
Early predictive biomarkers for lesion after transient cerebral ischemia.
Berthet C., Lei H., Gruetter R., Hirt L., 2011/03. Stroke, 42 (3) pp. 799-805. Peer-reviewed.
An episode mimicking a versive seizure in acute bilateral pontine stroke.
Alvarez V., Morier J., Hirt L., 2011. Journal of Clinical Neuroscience, 18 (8) pp. 1141-2. Peer-reviewed.
 
Neurologie [Therapeutic advances in neurology].
Siclari F., Du Pasquier R.A., Schluep M., Michel P., Hirt L., Kuntzer T., Rossetti A.O., Ghika J., Nater B., Vingerhoets F.J., 2011. Revue Médicale Suisse, 7 (277) pp. 50-56. Peer-reviewed.
 
Prognostic in Vivo Biomarkers for Lesion Development after Cerebral Ischemia
Hirt L., Berthet C., Lei H., Gruetter R., 2011. p. 27 dans 20th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
Role of homer 1 proteins in the calcium signaling pathway(s) underlying exo-endocytosis processes of glutamatergic slmvs in astrocytes
Cali C., Marchaland J., Ginet L., Hirt L., Truttmann A.C., Puyal J., Bezzi P., 2011. pp. S127 dans 10th European Meeting on Glial Cells in Health and Disease, GLIA. Peer-reviewed.
 
Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial
Bousser Marie-Germaine, Amarenco Pierre, Chamorro Angel, Fisher Marc, Ford Ian, Fox Kim M, Hennerici Michael G, Mattle Heinrich P, Rothwell Peter M, de Cordoüe Agnès et al., 2011. The Lancet, 377 (9782) pp. 2013-2022. Peer-reviewed.
 
Activation of c-Jun in the nuclei of neurons of the CA-1 in thrombin preconditioning occurs via PAR-1.
Price Melanie, Badaut Jerome, Thevenet Jonathan, Hirt Lorenz, 2010. Journal of Neuroscience Research, 88 (6) pp. 1338-1347.
 
Asymptomatic high flow subclavian steal in a patient with hemodialysis access.
Bron C., Hirt L., Halabi G., Saucy F., Qanadli S.D., Haesler E., 2010. The journal of vascular access, 11 (1) pp. 63-65. Peer-reviewed.
 
c-Jun N-terminal kinase pathway inhibition in intracerebral hemorrhage.
Michel-Monigadon Delphine, Bonny Christophe, Hirt Lorenz, 2010. Cerebrovascular Diseases, 29 (6) pp. 564-570.
 
Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial.
International Carotid Stenting Study investigators, Ederle J., Ederle J., Dobson J., Featherstone R.L., Bonati L.H., van der Worp H.B., de Borst G.J., Lo T.H., Gaines P. et al., 2010. Lancet, 375 (9719) pp. 985-997. Peer-reviewed.
 
Coagulation Factor Xa Activates Thrombin and Signals Ischemic Neuronal Death Via Par-1 and JNK in Ischemic Neural Tissue
Thevenet J., Angelillo-Scherrer A., Badaut J., Price M., Hirt L., 2010. p. 315 dans 19th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
JNK inhibition and inflammation after cerebral ischemia.
Benakis Corinne, Bonny Christophe, Hirt Lorenz, 2010. Brain, Behavior, and Immunity, 24 (5) pp. 800-811.
 
14.1T magnetic resonance spectroscopic evaluation of metabolic changes in the mouse striatum following transient middle cerebral artery occlusion
Berthet C., Lei H., Gruetter R., Hirt L., 2009. p. 108 dans 18th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
Bilateral carotid thrombus formation after strenuous coughing.
Siclari F., Hirt L., Meuli R., Fellmann F., Gailloud P., Michel P., 2009. European Journal of Neurology, 16 (7) pp. e122-e123.
 
Coagulation factor Xa activates thrombin in ischemic neural tissue.
Thevenet J., Angelillo-Scherrer A., Price M., Hirt L., 2009. Journal of Neurochemistry, 111 (3) pp. 828-836.
 
Evolution of the neurochemical profile after transient focal cerebral ischemia in the mouse brain.
Lei H., Berthet C., Hirt L., Gruetter R., 2009. Journal of Cerebral Blood Flow and Metabolism, 29 (4) pp. 811-819. Peer-reviewed.
 
Identification of early metabolic markers of various degrees of ischemia in the mouse brain by localized H-1 magnetic resonance spectroscopy
Berthet C., Lei H., Gruetter R., Hirt L., 2009. pp. S239 dans 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, Journal of Cerebral Blood Flow and Metabolism. Peer-reviewed.
 
Neuroprotective role of lactate after cerebral ischemia.
Berthet C., Lei H., Thevenet J., Gruetter R., Magistretti P.J., Hirt L., 2009. Journal of Cerebral Blood Flow and Metabolism, 29 (11) pp. 1780-1789. Peer-reviewed.
 
Protective role of early aquaporin 4 induction against postischemic edema formation.
Hirt L., Ternon B., Price M., Mastour N., Brunet J.F., Badaut J., 2009. Journal of cerebral blood flow and metabolism, 29 (2) pp. 423-433. Peer-reviewed.
 
Rationale and design of a randomized, double-blind, parallel-group study of terutroban 30 mg/day versus aspirin 100 mg/day in stroke patients: the prevention of cerebrovascular and cardiovascular events of ischemic origin with terutroban in patients with a history of ischemic stroke or transient ischemic attack (PERFORM) study.
Bousser M.G., Amarenco P., Chamorro A., Fisher M., Ford I., Fox K., Hennerici M.G., Mattle H.P., Rothwell P.M., PERFORM Study Investigators, 2009. Cerebrovascular Diseases, 27 (5) pp. 509-518. Peer-reviewed.
 
The C-Jun N-Terminal Kinase Inhibition in Intracerebral Hemorrhage
Michel-Monigadon D., Mottier V., Bonny C., Hirt L., 2009. p. 109 dans 18th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
The role of C-Jun N-terminal kinase in a mouse model of intracerebral hemorrhage
Michel-Monigadon D., Mottier V., Bonny C., Hirt L., 2009. pp. 490-491 dans 24th International Symposium on Cerebral Blood Flow and Metabolism/9th International Conference on Quantification of Brain Function with PET, Journal of Cerebral Blood Flow and Metabolism. Peer-reviewed.
 
MELAS and other mitochondrial disorders
Hirt Lorenz, 2008. Uncommon Causes of Stroke pp. 149-154.
 
REDUCTION OF MIGRAINES AFTER TREATMENT OF HEREDITARYHEMORRHAGIC TELANGIECTASIA (HHT)
Morier J., Goncalves-Matoso V., Doenz F., Jeanrenaud X., Hirt L., Michel P., 2008. p. 109 dans 17th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator.
Wiegler K., Bonny C., Coquoz D., Hirt L., 2008. Cerebrovascular Diseases (basel, Switzerland), 26 (4) pp. 360-366. Peer-reviewed.
 
Asymptomatic high flow subclavian steal in a patient with hemodialysis access
Bron C., Hirt L., Qanadli S, Halabi G., Saucy F., Haesler E., 2007/11. dans USSG 2007 8ème Congrès de l'Union des Sociétés Suisses des Maladies Vasculaires (Un. Schweiz. Gesellsch. für Gefässkrankheiten).
 
Aquaporin expression after thrombin preconditioning in ischemic mouse brain
Hirt L., Price M., Wiegler K., Mastour N., Brunet J.F., Badaut J., 2007. pp. 22-23 dans 16th European Stroke Conference, Cerebrovascular Diseases. Peer-reviewed.
 
Cerebrospinal fluid antimicroglial antibodies in Alzheimer disease: a putative marker of an ongoing inflammatory process.
McRae A., Martins R.N., Fonte J., Kraftsik R., Hirt L., Miklossy J., 2007. Experimental gerontology, 42 (4) pp. 355-63. Peer-reviewed.
 
Thrombin-induced ischemic tolerance is prevented by inhibiting c-jun N-terminal kinase.
Granziera C., Thevenet J., Price M., Wiegler K., Magistretti P.J., Badaut J., Hirt L., 2007. Brain research, 1148 pp. 217-25. Peer-reviewed.
 
Time course of aquaporin expression after transient focal cerebral ischemia in mice
Ribeiro Mde C., Hirt L., Bogousslavsky J., Regli L., Badaut J., 2006/05. Journal of Neuroscience Research, 83 (7) pp. 1231-40. Peer-reviewed.
 
Thrombin in ischemic neuronal death
de Castro Ribeiro M., Badaut J., Price M., Meins M., Bogousslavsky J., Monard D., Hirt L., 2006/03. Experimental Neurology, 198 (1) pp. 199-203. Peer-reviewed.
 
Apoptose et ischemie cerebrale [Cerebral ischemia and apoptosis]
Hirt L., Price M., Bogousslavsky J., 2005/04. Revue Médicale Suisse, 1 (17) pp. 1149-52.
 
Hypoxia/hypoglycemia preconditioning prevents the loss of functional electrical activity in organotypic slice cultures.
Badaut J., Hirt L., Price M., de Castro Ribeiro M., Magistretti P.J., Regli L., 2005. Brain research, 1051 (1-2) pp. 117-22. Peer-reviewed.
 
D-JNKI1, a cell-penetrating c-Jun-N-terminal kinase inhibitor, protects against cell death in severe cerebral ischemia
Hirt L., Badaut J., Thevenet J., Granziera C., Regli L., Maurer F., Bonny C., Bogousslavsky J., 2004/07. Stroke, 35 (7) pp. 1738-43. Peer-reviewed.
 
Controlled contrast transcranial Doppler and arterial blood gas analysis to quantify shunt through patent foramen ovale.
Devuyst G., Piechowski-Józwiak B., Karapanayiotides T., Fitting J.W., Kémeny V., Hirt L., Urbano L.A., Arnold P., van Melle G., Despland P.A. et al., 2004. Stroke, 35 (4) pp. 859-863.
 
L'accident vasculaire cérébral, une cause de mort rapide des neurones
Hirt Lorenz, Bogousslavsky Julien, 2003/02/12. Schweizer Archiv für Neurologie und Psychiatrie, 154 (02) pp. 81-85.
 
Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus
Endres M., Fan G., Hirt L., Jaenisch R., 2003/02. Journal of Cerebral Blood Flow and Metabolism, 23 (2) pp. 150-3. Peer-reviewed.
 
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia.
Borsello T., Clarke P.G.H., Hirt L., Vercelli A., Repici M., Schorderet D.F., Bogousslavsky J., Bonny C., 2003. Nature Medicine, 9 (9) pp. 1180-1186. Peer-reviewed.
 
Biochemistry of ischemic stroke
Barber P. A., Demchuk A. M., Hirt L., Buchan A. M., 2003. Advances in Neurology, 92 pp. 151-64.
 
The HD mutation does not alter neuronal death in the striatum of Hdh(Q92) knock-in mice after mild focal ischemia
Namura S., Hirt L., Wheeler V. C., McGinnis K. M., Hilditch-Maguire P., Moskowitz M. A., MacDonald M. E., Persichetti F., 2002/10. Neurobiology of Disease, 11 (1) pp. 147-54. Peer-reviewed.
 
Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals
Bates B., Hirt L., Thomas S. S., Akbarian S., Le D., Amin-Hanjani S., Whalen M., Jaenisch R., Moskowitz M. A., 2002/02. Neurobiology of Disease, 9 (1) pp. 24-37. Peer-reviewed.
 
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death
Katchanov J., Harms C., Gertz K., Hauck L., Waeber C., Hirt L., Priller J., von Harsdorf R., Bruck W., Hortnagl H. et al., 2001/07. Journal of Neuroscience, 21 (14) pp. 5045-53. Peer-reviewed.
 
Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia
Ma J., Qiu J., Hirt L., Dalkara T., Moskowitz M. A., 2001/06. British Journal of Pharmacology, 133 (3) pp. 345-50. Peer-reviewed.
 
Astrocyte-specific expression of aquaporin-9 in mouse brain is increased after transient focal cerebral ischemia
Badaut J., Hirt L., Granziera C., Bogousslavsky J., Magistretti P. J., Regli L., 2001/05. Journal of Cerebral Blood Flow and Metabolism, 21 (5) pp. 477-82. Peer-reviewed.
 
Nitric oxide is involved in ischemia-induced apoptosis in brain: a study in neuronal nitric oxide synthase null mice
Elibol B., Soylemezoglu F., Unal I., Fujii M., Hirt L., Huang P. L., Moskowitz M. A., Dalkara T., 2001. Neuroscience, 105 (1) pp. 79-86. Peer-reviewed.
 
Ocular mitochondrial myopathy evolving late in life into a disabling proximal myopathy associated with the mitochondrial DNA 3243 A to G mutation.
Hirt L., Maréchal C., Ghika J.A., Magistretti P.J., Bogousslavsky J., 2001. Journal of neurology, 248 (4) pp. 332-3. Peer-reviewed.
 
Fas receptor and neuronal cell death after spinal cord ischemia
Matsushita K., Wu Y., Qiu J., Lang-Lazdunski L., Hirt L., Waeber C., Hyman B. T., Yuan J., Moskowitz M. A., 2000/09. Journal of Neuroscience, 20 (18) pp. 6879-87. Peer-reviewed.
 
Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression
Endres M., Fan G., Hirt L., Fujii M., Matsushita K., Liu X., Jaenisch R., Moskowitz M. A., 2000/01. Journal of Cerebral Blood Flow and Metabolism, 20 (1) pp. 139-44. Peer-reviewed.
 
Spinal cord ischemia. Development of a model in the mouse
Lang-Lazdunski L., Matsushita K., Hirt L., Waeber C., Vonsattel J. P., Moskowitz M. A., Dietrich W. D., 2000/01. Stroke, 31 (1) pp. 208-13. Peer-reviewed.
 
Sniff nasal pressure: a sensitive respiratory test to assess progression of amyotrophic lateral sclerosis
Fitting J. W., Paillex R., Hirt L., Aebischer P., Schluep M., 1999/12. Annals of Neurology, 46 (6) pp. 887-93. Peer-reviewed.
 
Myopathies mitochondriales oculaires: un eventail de presentations cliniques. [Ocular mitochondrial myopathies: a spectrum of clinical presentations]
Glutz von Blotzheim S., Borruat F. X., Hirt L., 1998/05. Klinische Monatsblatter fur Augenheilkunde, 212 (5) pp. 299-300.
 
Ragged-red fibers and complex I deficiency in a neonate with arthrogryposis congenita
Laubscher B., Janzer R. C., Krahenbuhl S., Hirt L., Deonna T., 1997/10. Pediatric Neurology, 17 (3) pp. 249-51. Peer-reviewed.
 
Atteintes nerf-muscle et accidents cerebrovasculaires. [Neuromuscular involvement and cerebrovascular accidents]
Kuntzer T., Hirt L., Bogousslavsky J., 1996/08. Revue Médicale de la Suisse Romande, 116 (8) pp. 605-9. Peer-reviewed.
 
Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF.
Aebischer P., Pochon N.A., Heyd B., Deglon N., Joseph J.M., Zurn A.D., Baetge E.E., Hammang J.P., Goddard M., Lysaght M. et al., 1996/05. Human Gene Therapy, 7 (7) pp. 851-860. Peer-reviewed.
 
Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients.
Aebischer P., Schluep M., Déglon N., Joseph J.M., Hirt L., Heyd B., Goddard M., Hammang J.P., Zurn A.D., Kato A.C. et al., 1996. Nature Medicine, 2 (6) pp. 696-699.
 
Large deletion (7.2 kb) of mitochondrial DNA with novel boundaries in a case of progressive external ophthalmoplegia.
Hirt L., Magistretti P.J., Bogousslavsky J., Boulat O., Borruat F.X., 1996. Journal of neurology, neurosurgery, and psychiatry, 61 (4) pp. 422-3. Peer-reviewed.
 
Mitochondrial DNA and neurologic diseases
Hirt Lorenz, Regli Franco, 1996. Schweizer Archiv fur Neurologie und Psychiatrie, 147 pp. 221-225.
 
Neuropathie optique alcoolo-tabagique: un piege diagnostique de la neuropathie optique de Leber. [Optic neuropathy caused by alcoholism and smoking: a diagnostic pitfall of Leber's optic neuropathy]
Borruat F. X., Hirt L., Regli F., 1994/11. Revue Neurologique, 150 (11) pp. 799-801. Peer-reviewed.
 
Nucleotide sequence of human papillomavirus (HPV) type 41: an unusual HPV type without a typical E2 binding site consensus sequence.
Hirt L., Hirsch-Behnam A., de Villiers E.M., 1991/03. Virus Research, 18 (2-3) pp. 179-189. Peer-reviewed.
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