Direction du Département de médecine de laboratoire et pathologie

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Publications | Mémoires et thèses

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62 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
 
Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide in People With HIV.
Damas J., Munting A., Fellay J., Haerry D., Marzolini C., Tarr P.E., Steffen A., Braun D.L., Stoeckle M., Bernasconi E. et al., 2024/10/15. Clinical infectious diseases, 79 (4) pp. 990-998. Peer-reviewed.
 
Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies.
Fernbach S., Mair N.K., Abela I.A., Groen K., Kuratli R., Lork M., Thorball C.W., Bernasconi E., Filippidis P., Leuzinger K. et al., 2024/09/02. The Journal of experimental medicine, 221 (9). Peer-reviewed.
Use of GLP1 receptor agonists in early pregnancy and reproductive safety: a multicentre, observational, prospective cohort study based on the databases of six Teratology Information Services.
Dao K., Shechtman S., Weber-Schoendorfer C., Diav-Citrin O., Murad R.H., Berlin M., Hazan A., Richardson J.L., Eleftheriou G., Rousson V. et al., 2024/04/24. BMJ open, 14 (4) pp. e083550. Peer-reviewed.
Drug- and Toxin-Induced Opsoclonus - a Systematized Review, including a Case Report on Amantadine-Induced Opsoclonus in Multiple System Atrophy.
Cannilla H., Messe M., Girardin F., Borruat F.X., Bally J.F., 2024. Tremor and other hyperkinetic movements, 14 p. 23. Peer-reviewed.
Pregnancy outcomes after GLP-1 agonist exposure in early pregnancy
Winterfeld Ursula, Dao Kim, Haefliger David, Diezi Léonore, Girardin François, 2023/11/23. Swissmedic Vigilance News. Peer-reviewed.
Cost-effectiveness of Hepatocellular Carcinoma Surveillance Strategies in Switzerland
Goossens Nicolas, Garay Osvaldo Ulises, Wolf Cyrill, Ambühl Louisa Elena, Kugler Vanessa, Girardin François, 2023/09/11., Annual Meeting of the Swiss Society of Gastroenterology (SGG-SSG), the Swiss Society of Visceral Surgery (SGVC-SSCV), the Swiss Association for the Study of the Liver (SASL) and the Swiss Society of Endoscopy Nurses and Associates (SVEP-ASPE), 14-15 September pp. 6S dans Swiss Medical Weekly.
Supplementum 272: Abstracts of the Annual meeting of the Swiss Society of Gastroenterology, the Swiss Society of Visceral Surgery, the Swiss Association for the Study of the Liver and the Swiss Society of Endoscopy Nurses and Associates
Juillerat Pascal, Tachet Jérémie, Mercier Thomas, Versace François, Guidi Monia, Buclin Thierry, Decosterd Laurent, Choong Eva, Girardin François, 2023/09/11., Annual meeting of the Swiss Society of Gastroenterology , the Swiss Society of Visceral Surgery, the Swiss Association for the Study of the Liver, the Swiss Society of Endoscopy Nurses and Associates pp. s3511 dans Swiss Medical Weekly, François. Peer-reviewed, SMW Supporting Association.
 
A Highly Sensitive HPLC-MS/MS MethodFor Multiplex Analysis Of Janus KinaseInhibitors In Plasma
Tachet J., Mercier T., André P., Guidi M., Buclin T., Decosterd L., Choong E., Girardin F., 2023/07. dans 19th World Congress of Basic and Clinical Pharmacology (WCP), Glasgow, July 2023.
Four cases of audio-vestibular disorders related to immunisation with SARS-CoV-2 mRNA vaccines.
Ekobena P., Rothuizen L.E., Bedussi F., Guilcher P., Meylan S., Ceschi A., Girardin F., Dao K., 2023/06. International journal of audiology, 62 (6) pp. 587-591. Peer-reviewed.
Ibrutinib and venetoclax associated with progressive multifocal leukoencephalopathy
Haefliger David, Girardin François, 2023/05/30. Swissmedic Vigilance News. Peer-reviewed.
JAK inhibitors: need for dosage individualisation?
Tachet Jérémie, Girardin François, 2023/05/30. Swissmedic Vigilance News . Peer-reviewed.
Combining European and U.S. risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study.
de La Harpe R., Thorball C.W., Redin C., Fournier S., Müller O., Strambo D., Michel P., Vollenweider P., Marques-Vidal P., Fellay J. et al., 2023/05/09. European journal of preventive cardiology, 30 (7) pp. 561-571. Peer-reviewed.
Associations of genetic and infectious risk factors with coronary heart disease.
Hodel F., Xu Z.M., Thorball C.W., de La Harpe R., Letang-Mathieu P., Brenner N., Butt J., Bender N., Waterboer T., Marques-Vidal P.M. et al., 2023. eLife, 12 pp. e79742. Peer-reviewed.
 
Variability of Primary Sjögren's Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.
Trutschel D., Bost P., Mariette X., Bondet V., Llibre A., Posseme C., Charbit B., Thorball C.W., Jonsson R., Lessard C.J. et al., 2022/12. Arthritis & rheumatology, 74 (12) pp. 1991-2002. Peer-reviewed.
Inhibiteurs des Janus kinases : nouvelles perspectives pour la médecine de précision ? [Janus kinase inhibitors : new perspectives for precision medicine ?]
Tachet J., Dumusc A., Conrad C., Grandoni F., Chalandon Y., Ribi C., Buclin T., Girardin F., 2022/10/19. Revue medicale suisse, 18 (800) pp. 1979-1983. Peer-reviewed.
Host genomics of SARS-CoV-2 infection.
Redin C., Thorball C.W., Fellay J., 2022/08. European journal of human genetics, 30 (8) pp. 908-914. Peer-reviewed.
Improving polygenic prediction with genetically inferred ancestry.
Naret O., Kutalik Z., Hodel F., Xu Z.M., Marques-Vidal P., Fellay J., 2022/07/14. HGG advances, 3 (3) p. 100109. Peer-reviewed.
BRAF Rearrangements and BRAF V600E Mutations Are Seen in a Subset of Pancreatic Carcinomas With Acinar Differentiation.
Ghosh T., Greipp P.T., Knutson D., Kloft-Nelson S., Jenkins S., Mounajjed T., Said S., La Rosa S., Vanoli A., Sessa F. et al., 2022/07/01. Archives of pathology & laboratory medicine, 146 (7) pp. 840-845. Peer-reviewed.
 
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Manry J., Bastard P., Gervais A., Le Voyer T., Rosain J., Philippot Q., Michailidis E., Hoffmann H.H., Eto S., Garcia-Prat M. et al., 2022/05/24. Proceedings of the National Academy of Sciences of the United States of America, 119 (21) pp. e2200413119. Peer-reviewed.
 
A highly virulent variant of HIV-1 circulating in the Netherlands.
Wymant C., Bezemer D., Blanquart F., Ferretti L., Gall A., Hall M., Golubchik T., Bakker M., Ong S.H., Zhao L. et al., 2022/02/04. Science, 375 (6580) pp. 540-545. Peer-reviewed.
A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection.
Andreakos E., Abel L., Vinh D.C., Kaja E., Drolet B.A., Zhang Q., O'Farrelly C., Novelli G., Rodríguez-Gallego C., Haerynck F. et al., 2022/02. Nature immunology, 23 (2) pp. 159-164. Peer-reviewed.
Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV.
Bick A.G., Popadin K., Thorball C.W., Uddin M.M., Zanni M.V., Yu B., Cavassini M., Rauch A., Tarr P., Schmid P. et al., 2022/01/12. Scientific reports, 12 (1) p. 577. Peer-reviewed.
Blood virosphere in febrile Tanzanian children.
Cordey S., Laubscher F., Hartley M.A., Junier T., Keitel K., Docquier M., Guex N., Iseli C., Vieille G., Le Mercier P. et al., 2021/12. Emerging microbes & infections, 10 (1) pp. 982-993. Peer-reviewed.
From Your Nose to Your Toes: A Review of Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic‒Associated Pernio.
Arkin L.M., Moon J.J., Tran J.M., Asgari S., O'Farrelly C., Casanova J.L., Cowen E.W., Mays J.W., Singh A.M., Drolet B.A. et al., 2021/12. The Journal of investigative dermatology, 141 (12) pp. 2791-2796. Peer-reviewed.
 
Impact of Delaying Antiretroviral Treatment During Primary Human Immunodeficiency Virus Infection on Telomere Length.
Raffenberg M., Engel T., Schoepf I.C., Kootstra N.A., Reiss P., Braun D.L., Thorball C.W., Fellay J., Kouyos R.D., Ledergerber B. et al., 2021/11/22. The Journal of infectious diseases, 224 (10) pp. 1775-1784. Peer-reviewed.
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.
Smith D.A., Fernandez-Antunez C., Magri A., Bowden R., Chaturvedi N., Fellay J., McLauchlan J., Foster G.R., Irving W.L., STOP-HCV Consortium et al., 2021/10/20. Nature communications, 12 (1) p. 6105. Peer-reviewed.
Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption.
Froelicher D., Troncoso-Pastoriza J.R., Raisaro J.L., Cuendet M.A., Sousa J.S., Cho H., Berger B., Fellay J., Hubaux J.P., 2021/10/11. Nature communications, 12 (1) p. 5910. Peer-reviewed.
 
Telomere Length, Traditional Risk Factors, Factors Related to Human Immunodeficiency Virus (HIV) and Coronary Artery Disease Events in Swiss Persons Living With HIV.
Engel T., Raffenberg M., Schoepf I.C., Kootstra N.A., Reiss P., Thorball C.W., Hasse B., Hirzel C., Wissel K., Roth J.A. et al., 2021/10/05. Clinical infectious diseases, 73 (7) pp. e2070-e2076. Peer-reviewed.
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.
Luo Y., Kanai M., Choi W., Li X., Sakaue S., Yamamoto K., Ogawa K., Gutierrez-Arcelus M., Gregersen P.K., Stuart P.E. et al., 2021/10. Nature genetics, 53 (10) pp. 1504-1516. Peer-reviewed.
 
Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores.
Dietrich L.G., Thorball C.W., Ryom L., Burkhalter F., Hasse B., Thurnheer M.C., Weisser M., Schmid P., Bernasconi E., Darling KEA et al., 2021/06/15. The Journal of infectious diseases, 223 (12) pp. 2145-2153. Peer-reviewed.
 
Author Correction: The influence of human genetic variation on Epstein-Barr virus sequence diversity.
Rüeger S., Hammer C., Loetscher A., McLaren P.J., Lawless D., Naret O., Khanna N., Bernasconi E., Cavassini M., Günthard H.F. et al., 2021/04/20..
Mortality and high risk of major adverse events in patients with COVID-19 and history of cardiovascular disease.
Tessitore E., Carballo D., Poncet A., Perrin N., Follonier C., Assouline B., Carballo S., Girardin F., Mach F., 2021/04. Open heart, 8 (1) pp. e001526. Peer-reviewed.
Pharmacovigilance [Pharmacovigilance update]
Ekobena P., Ivanyuk A., Livio F., 2021/01/13. Revue medicale suisse, 17 (720-1) pp. 80-84. Peer-reviewed.
Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles.
Benet S., Gálvez C., Drobniewski F., Kontsevaya I., Arias L., Monguió-Tortajada M., Erkizia I., Urrea V., Ong R.Y., Luquin M. et al., 2021/01. Journal of extracellular vesicles, 10 (3) pp. e12046. Peer-reviewed.
 
Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment.
Thorball C.W., Borghesi A., Bachmann N., Von Siebenthal C., Vongrad V., Turk T., Neumann K., Beerenwinkel N., Bogojeska J., Roth V. et al., 2020/12/01. Journal of acquired immune deficiency syndromes, 85 (4) pp. 517-524. Peer-reviewed.
2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0.
Ryom L., Cotter A., De Miguel R., Béguelin C., Podlekareva D., Arribas J.R., Marzolini C., Mallon P., Rauch A., Kirk O. et al., 2020/11. HIV medicine, 21 (10) pp. 617-624. Peer-reviewed.
 
Performance and Application of 16S rRNA Gene Cycle Sequencing for Routine Identification of Bacteria in the Clinical Microbiology Laboratory.
Church D.L., Cerutti L., Gürtler A., Griener T., Zelazny A., Emler S., 2020/09/16. Clinical microbiology reviews, 33 (4) pp. e00053-19. Peer-reviewed.
Evaluation of a New <sup>177</sup>Lu-Labeled Somatostatin Analog for the Treatment of Tumors Expressing Somatostatin Receptor Subtypes 2 and 5.
Mansi R., Nicolas G.P., Del Pozzo L., Abid K.A., Grouzmann E., Fani M., 2020/09/11. Molecules, 25 (18) p. 4155. Peer-reviewed.
La médecine de précision : au carrefour de la biologie moléculaire, des sciences de l’information et des humanités [Precision medicine : at the crossroad of molecular biology, information sciences and humanities]
Gosselin R.D., Redin C., Ristorcelli É., Raisaro J.L., Fellay J., 2020/09/02. Revue medicale suisse, 16 (704) pp. 1574-1578. Peer-reviewed.
 
Ongoing evolution of KRAB zinc finger protein-coding genes in modern humans
Christian Thorball, Evarist Planet, Jonas de Tribolet-Hardy, Alexandre Coudray, Jacques Fellay, Priscilla Turelli, Didier Trono, 2020/09/01..
 
Phenotype prediction from genome-wide genotyping data: a crowdsourcing experiment
Olivier Naret, David AA Baranger, Sharada Prasanna Mohanty, Bastian Greshake Tzovaras, Marcel Salathé, Jacques Fellay, 2020/08/25..
Assessing the impact of non-pharmaceutical interventions on SARS-CoV-2 transmission in Switzerland
Lemaitre Joseph C, Perez-Saez Javier, Azman Andrew S, Rinaldo Andrea, Fellay Jacques, 2020/05/30. Swiss Medical Weekly.
Data protection and ethics requirements for multisite research with health data: a comparative examination of legislative governance frameworks and the role of data protection technologies.
Scheibner J., Ienca M., Kechagia S., Troncoso-Pastoriza J.R., Raisaro J.L., Hubaux J.P., Fellay J., Vayena E., 2020. Journal of law and the biosciences, 7 (1) pp. lsaa010. Peer-reviewed.
 
Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation
Thomas Junier, Laurent Kaiser, Nimisha Chaturvedi, Jacques Fellay, 2019/12/02..
 
A global scientific strategy to cure hepatitis B.
Revill P.A., Chisari F.V., Block J.M., Dandri M., Gehring A.J., Guo H., Hu J., Kramvis A., Lampertico P., Janssen HLA et al., 2019/07. The lancet. Gastroenterology & hepatology, 4 (7) pp. 545-558. Peer-reviewed.
 
Increasing hepatitis C virus screening in people who inject drugs in Switzerland using rapid antibody saliva and dried blood spot testing: A cost-effectiveness analysis.
Girardin F., Hearmon N., Negro F., Eddowes L., Bruggmann P., Castro E., 2019/02. Journal of viral hepatitis, 26 (2) pp. 236-245. Peer-reviewed.
 
HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control
Jatin Arora, Paul McLaren, Nimisha Chaturvedi, Mary Carrington, Jacques Fellay, Tobias Lenz, 2019/01/15. Proceedings of the National Academy of Sciences.
 
Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis.
Maffucci P, Bigio B, Rapaport F, Cobat A, Borghesi A, Lopez M, Patin E, Bolze A, Shang L, Bendavid M et al., 2018/12. Proceedings of the National Academy of Sciences of the United States of America.
 
Pervasive Adaptation of Hepatitis C Virus to Interferon Lambda Polymorphism Across Multiple Genotypes
Nimisha Chaturvedi, Evguenia Svarovskaia, Hongmei Mo, Anu Osinusi, Diana Brainard, G Mani Subramanian, John McHutchison, Stefan Zeuzem, Jacques Fellay, 2018/11/30..
 
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM et al., 2018/04. The Journal of clinical investigation.
 
Are privacy-enhancing technologies for genomic data ready for the clinic? A survey of medical experts of the Swiss HIV Cohort Study.
Raisaro J.L., McLaren P.J., Fellay J., Cavassini M., Klersy C., Hubaux J.P., Swiss HIV Cohort Study, 2018/03. Journal of biomedical informatics, 79 pp. 1-6. Peer-reviewed.
 
Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives.
Abel L., Fellay J., Haas D.W., Schurr E., Srikrishna G., Urbanowski M., Chaturvedi N., Srinivasan S., Johnson D.H., Bishai W.R., 2018/03. The Lancet. Infectious diseases, 18 (3) pp. e64-e75. Peer-reviewed.
 
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.
Patin E, Hasan M, Bergstedt J, Rouilly V, Libri V, Urrutia A, Alanio C, Scepanovic P, Hammer C, Jönsson F et al., 2018/02. Nature immunology.
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.
Piasecka B., Duffy D., Urrutia A., Quach H., Patin E., Posseme C., Bergstedt J., Charbit B., Rouilly V., MacPherson C.R. et al., 2018/01/16. Proceedings of the National Academy of Sciences of the United States of America, 115 (3) pp. E488-E497. Peer-reviewed.
Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes.
Naret O., Chaturvedi N., Bartha I., Hammer C., Fellay J., Swiss HIV Cohort Study (SHCS), 2018. Frontiers in genetics, 9 p. 266. Peer-reviewed.
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver.
Wymant C, Blanquart F, Golubchik T, Gall A, Bakker M, Bezemer D, Croucher NJ, Hall M, Hillebregt M, Ong SH et al., 2018/01. Virus evolution.
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.
Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK et al., 2018/01. Science (New York, N.Y.).
 
Sequence Alignment Through the Looking Glass
Appuswamy R, Fellay J, Chaturvedi N, 2018/01..
HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.
Fellay Jacques, 2017/11. Journal of virology.
Evaluating the Impact of Functional Genetic Variation on HIV-1 Control
Paul J McLaren, Sara L Pulit, Deepti Gurdasani, Istvan Bartha, Patrick R Shea, Cristina Pomilla, Namrata Gupta, Effrossyni Gkrania-Klotsas, Elizabeth H Young, Norbert Bannert et al., 2017/09/09. The Journal of Infectious Diseases.
 
Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe
François Blanquart, Chris Wymant, Marion Cornelissen, Astrid Gall, Margreet Bakker, Daniela Bezemer, Matthew Hall, Mariska Hillebregt, Swee Hoe Ong, Jan Albert et al., 2017/06. PLOS Biology.
Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.
Ansari M.A., Pedergnana V., L C Ip C., Magri A., Von Delft A., Bonsall D., Chaturvedi N., Bartha I., Smith D., Nicholson G. et al., 2017/05. Nature genetics, 49 (5) pp. 666-673. Peer-reviewed.
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