Advanced Age Psychiatry - Center

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617 publications

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Therapeutic Drug Monitoring of Olanzapine: Effects of Clinical Factors on Plasma Concentrations in Psychiatric Patients.
Ansermot N., Vathanarasa H., Ranjbar S., Gholam M., Crettol S., Vandenberghe F., Gamma F., Plessen K.J., von Gunten A., Conus P. et al. Therapeutic drug monitoring. Peer-reviewed.
 
Successful Treatment of Both Refractory Neuroleptic Malignant Syndrome and Subsequent Catatonia With Electroconvulsive Therapy in a Patient With Suspected Kufs Disease.
Celik S., de Gennaro V., C-P-Silva J., Swierkosz-Lenart K., von Gunten A. The journal of ECT. Peer-reviewed.
 
Benzodiazepine-receptor agonist prescription in a population of hospitalised patients in four psychogeriatric units in Switzerland.
Dalmau I Ribas M., Sauser J., Gillès de Pélichy E., Méndez Rubio M., Schuster J.P., Von Gunten A., Haba-Rubio J. Journal of sleep research. Peer-reviewed.
 
Neuropsychiatric symptoms in cognitive decline and Alzheimer's disease: biomarker discovery using plasma proteomics.
Rabl M., Clark C., Dayon L., Popp J., Alzheimer's Disease Neuroimaging Initiative Journal of neurology, neurosurgery, and psychiatry. Peer-reviewed.
 
Mortality among older people with late-onset and non-late-onset schizophrenia: A 5-year prospective multicenter study.
Rezaei K., Sánchez-Rico M., Garcés-González M.S., Vandel P., Schuster J.P., Blanco C., Limosin F., Hoertel N., CSA Study Group Schizophrenia research. Peer-reviewed.
 
Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort.
Piras M., Lin J., Sadler M.C., Ranjbar S., Grosu C., Laaboub N., Preisig M., Gamma F., Plessen K.J., von Gunten A. et al., 2024/11/15. Translational psychiatry, 14 (1) p. 471. Peer-reviewed.
Prediction of electroconvulsive therapy response and remission in late-life depression: a review
Pozuelo Moyano Beatriz, Swierkosz Lenart Kevin, Rosselet Amoussou Joëlle, Von Gunten Armin, Schuster Jean-Pierre, 2024/11/05. Swiss Medical Weekly, 154 (11) p. 3684. Peer-reviewed.
Prescribing pattern insights from a longitudinal study of older adult inpatients with polypharmacy and chronic non-cancer pain.
Goetschi A.N., Verloo H., Wernli B., Wertli M.M., Meyer-Massetti C., 2024/11. European journal of pain, 28 (10) pp. 1645-1655. Peer-reviewed.
 
Using Existing Clinical Data to Measure Older Adult Inpatients' Frailty at Admission and Discharge: Hospital Patient Register Study.
Wernli B., Verloo H., von Gunten A., Pereira F., 2024/10/28. JMIR aging, 7 pp. e54839. Peer-reviewed.
Early-life adversity predicting the incidence of multisite chronic pain in the general population.
Rouch I., Strippoli M.F., Dorey J.M., Laurent B., Ranjbar S., Marques-Vidal P.M., Berna C., Suter M., Vaucher J., von Gunten A. et al., 2024/10/08. European psychiatry, 67 (1) pp. e67. Peer-reviewed.
 
Measuring Nurses' Knowledge and Awareness of Climate Change and Climate-Associated Diseases: Systematic Review of Existing Instruments.
Portela Dos Santos O., Perruchoud É., Pereira F., Alves P., Verloo H., 2024/10/08. Nursing reports, 14 (4) pp. 2850-2876. Peer-reviewed.
 
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study.
Smith R.G., Pishva E., Kouhsar M., Imm J., Dobricic V., Johannsen P., Wittig M., Franke A., Vandenberghe R., Schaeverbeke J. et al., 2024/10. Alzheimer's & dementia, 20 (10) pp. 6722-6739. Peer-reviewed.
Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Koetsier J., Cavill R., Reijnders R., Harvey J., Homann J., Kouhsar M., Deckers K., Köhler S., Eijssen LMT, van den Hove DLA et al., 2024/10. Alzheimer's & dementia, 20 (10) pp. 6682-6698. Peer-reviewed.
Dietary patterns, inflammatory biomarkers and cognition in older adults: An analysis of three population-based cohorts.
Ortega N., Schütte L., de Crom TOE, Voortman T., Okereke O.I., Vinceti M., von Gunten A., Marques-Vidal P., Rodondi N., Chiolero A. et al., 2024/10. Clinical nutrition, 43 (10) pp. 2336-2343. Peer-reviewed.
 
Age-related changes in sleep spindle characteristics in individuals over 75 years of age: a retrospective and comparative study.
Poirson B., Vandel P., Bourdin H., Galli S., 2024/09/20. BMC geriatrics, 24 (1) p. 778. Peer-reviewed.
 
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease.
Delvenne A., Gobom J., Schindler S.E., Kate M.T., Reus L.M., Dobricic V., Tijms B.M., Benzinger TLS, Cruchaga C., Teunissen C.E. et al., 2024/09. Alzheimer's & dementia, 20 (9) pp. 6205-6220. Peer-reviewed.
Aripiprazole dose associations with metabolic adverse effect: Results from a longitudinal study.
Piras M., Popovic I., Ranjbar S., Grosu C., Laaboub N., Sentissi O., Lakhal M.H., Gamma F., Plessen K.J., von Gunten A. et al., 2024/08. Schizophrenia research, 270 pp. 403-409. Peer-reviewed.
 
Plasma neurofilament light, glial fibrillary acid protein, and phosphorylated tau 181 as biomarkers for neuropsychiatric symptoms and related clinical disease progression.
Rabl M., Zullo L., Lewczuk P., Kornhuber J., Karikari T.K., Blennow K., Zetterberg H., Bavato F., Quednow B.B., Seifritz E. et al., 2024/07/25. Alzheimer's research & therapy, 16 (1) p. 165. Peer-reviewed.
 
Increased sexual function after intake of clomethiazole.
Dalmau I Ribas M., Mendez Rubio M., von Gunten A., 2024/07/23. BMJ case reports, 17 (7). Peer-reviewed.
 
Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies.
Delvenne A., Vandendriessche C., Gobom J., Burgelman M., Dujardin P., De Nolf C., Tijms B.M., Teunissen C.E., Schindler S.E., Verhey F. et al., 2024/07/18. Fluids and barriers of the CNS, 21 (1) p. 58. Peer-reviewed.
Mental health among centenarians living in Switzerland.
Uittenhove K., Rohner S.L., Falciola J., Gomes da Rocha C., Röcke C., Cavalli S., Herrmann F., Jopp D.S., von Gunten A., 2024/07. Psychogeriatrics, 24 (4) pp. 887-896. Peer-reviewed.
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.
Gómez-Pascual A., Naccache T., Xu J., Hooshmand K., Wretlind A., Gabrielli M., Lombardo M.T., Shi L., Buckley N.J., Tijms B.M. et al., 2024/06. Computers in biology and medicine, 176 p. 108588. Peer-reviewed.
 
Using AI-Based Technologies to Help Nurses Detect Behavioral Disorders: Narrative Literature Review.
Fernandes S., von Gunten A., Verloo H., 2024/05/28. JMIR nursing, 7 pp. e54496. Peer-reviewed.
 
Profiles of centenarians' functioning: linking functional and cognitive capacity with depressive symptoms.
Uittenhove K., Lampraki C., da Rocha C.G., Rott C., von Gunten A., Jopp D.S., 2024/05/23. BMC geriatrics, 24 (1) p. 451. Peer-reviewed.
 
Associations of Valproate Doses With Weight Gain in Adult Psychiatric Patients: A 1-Year Prospective Cohort Study.
Grosu C., Hatoum W., Piras M., Laaboub N., Ranjbar S., Gamma F., Plessen K.J., von Gunten A., Preisig M., Conus P. et al., 2024/03/27. The Journal of clinical psychiatry, 85 (2). Peer-reviewed.
Plasma neurofilament light, glial fibrillary acid protein, and phosphorylated tau 181 as biomarkers for neuropsychiatric symptoms and related clinical disease progression.
Rabl M., Zullo L., Lewczuk P., Kornhuber J., Karikari T.K., Blennow K., Zetterberg H., Bavato F., Quednow B.B., Seifritz E. et al., 2024/03/22..
DNA methylation may partly explain psychotropic drug-induced metabolic side effects: results from a prospective 1-month observational study.
Dubath C., Porcu E., Delacrétaz A., Grosu C., Laaboub N., Piras M., von Gunten A., Conus P., Plessen K.J., Kutalik Z. et al., 2024/02/28. Clinical epigenetics, 16 (1) p. 36. Peer-reviewed.
Cholesterol-metabolism, plant sterols, and long-term cognitive decline in older people - Effects of sex and APOEe4.
Spinedi M., Clark C., Zullo L., Kerksiek A., Pistis G., Castelao E., von Gunten A., Preisig M., Lütjohann D., Popp J., 2024/02/16. iScience, 27 (2) p. 109013. Peer-reviewed.
 
[Recommendations for the diagnostic and therapy of behavioural and psychological symptoms of dementia (BPSD)].
Savaskan E., Georgescu D., Becker S., Benkert B., Blessing A., Bürge M., Felbecker A., Hatzinger M., Hemmeter U.M., Hirsbrunner T. et al., 2024/02. Praxis, 113 (2) pp. 34-43. Peer-reviewed.
Effect of dairy consumption on cognition in older adults: A population-based cohort study.
Ortega N., Carmeli C., Efthimiou O., Beer J.H., Gunten A.V., Preisig M., Zullo L., Vaucher J., Vollenweider P., Marques-Vidal P. et al., 2024/02. The journal of nutrition, health & aging, 28 (2) p. 100031. Peer-reviewed.
Obstructive sleep apnea and cognitive functioning in the older general population: The moderating effect of age, sex, ApoE4, and obesity.
Marchi N.A., Berger M., Solelhac G., Bayon V., Haba-Rubio J., Legault J., Thompson C., Gosselin N., Vollenweider P., Marques-Vidal P. et al., 2024/02. Journal of sleep research, 33 (1) pp. e13938. Peer-reviewed.
 
Psychiatrie : ce qui a changé en 2023 [Psychiatry: what's new in 2023]
Conus P., Kolypczuk P., Dukes R., Pozuelo Moyano B., Swierkosz-Lenart K., Schuster J.P., Clerc M.T., Von Gunten A., Vandel P., 2024/01/31. Revue medicale suisse, 20 (859) pp. 269-272. Peer-reviewed.
Metabolic disturbances are risk factors for readmission to psychiatric hospitals in non-smokers but not in smokers: results from a Swiss psychiatric cohort and in first-episode psychosis patients.
Laaboub N., Locatelli I., Grosu C., Piras M., Ngoc T.H., Ranjbar S., Preisig M., Elowe J., von Gunten A., Conus P. et al., 2024. Frontiers in psychiatry, 15 p. 1256416. Peer-reviewed.
Prediction of antipsychotics efficacy based on a polygenic risk score: a real-world cohort study.
De Pieri M., Ferrari M., Pistis G., Gamma F., Marino F., Von Gunten A., Conus P., Cosentino M., Eap C.B., 2024. Frontiers in pharmacology, 15 p. 1274442. Peer-reviewed.
 
Relationship between Depression and Falls among Nursing Home Residents: an Integrative Review (Preprint)
Matos Queirós Alcina, von Gunten Armin, Rosselet Amoussou Joëlle, Lima Andreia, Martins Maria Manuela, Verloo Henk, 2024..
Antidepressants and the risk of bleeding in the era of anti-amyloid drugs.
Pozuelo Moyano B., Salvioni P., Zullo L., Rouaud O., von Gunten A., Girardin F.R., Allali G., 2023/12. Alzheimer's & dementia, 19 (12) pp. 5847-5848. Peer-reviewed.
 
Corrigendum to "Periodic leg movements during sleep and cognitive functioning in the older general population" [Sleep Med 109 (2023) 197-201].
Marchi N.A., Peci A., Haba-Rubio J., Solelhac G., Bayon V., Berger M., Vollenweider P., Marques-Vidal P., von Gunten A., Strippoli M.F. et al., 2023/11. Sleep medicine, 111 p. 207. Peer-reviewed.
Measuring Nurses' Knowledge and Awareness of Climate Change and Climate-Associated Diseases: Protocol for a Systematic Review of Existing Instruments.
Portela Dos Santos O., Melly P., Joost S., Verloo H., 2023/10/23. International journal of environmental research and public health, 20 (20) p. 6963. Peer-reviewed.
Relationship Between Depression and Falls Among Nursing Home Residents: Protocol for an Integrative Review.
Matos Queirós A., von Gunten A., Rosselet Amoussou J., Martins M.M., Verloo H., 2023/10/19. JMIR research protocols, 12 pp. e46995. Peer-reviewed.
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann A., Ohlei O., Küçükali F., Bos I.J., Timsina J., Vos S., Prokopenko D., Tijms B.M., Andreasson U., Blennow K. et al., 2023/10/04. Genome medicine, 15 (1) p. 79. Peer-reviewed.
 
La douleur chronique, un langage malhabile du corps [Chronic pain, a clumsy body language]
Rouch I., Dorey J.M., Saint-Martin H., Von Gunten A., Preisig M., Laurent B., 2023/09/20. Revue medicale suisse, 19 (842) pp. 1690-1692. Peer-reviewed.
Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes.
Le Guen Y., Luo G., Ambati A., Damotte V., Jansen I., Yu E., Nicolas A., de Rojas I., Peixoto Leal T., Miyashita A. et al., 2023/09/05. Proceedings of the National Academy of Sciences of the United States of America, 120 (36) pp. e2302720120. Peer-reviewed.
Development of a patient-centred medication management model for polymedicated home-dwelling older adults after hospital discharge: results of a mixed methods study
Pereira Filipa, Meyer-Massetti Carla, del Río Carral María, von Gunten Armin, Wernli Boris, Verloo Henk, 2023/09. BMJ Open, 13 (9) pp. e072738. Peer-reviewed.
Periodic leg movements during sleep and cognitive functioning in the older general population.
Marchi N.A., Peci A., Haba-Rubio J., Solelhac G., Bayon V., Berger M., Vollenweider P., Marques-Vidal P., von Gunten A., Strippoli M.F. et al., 2023/09. Sleep medicine, 109 pp. 197-201. Peer-reviewed.
 
Psychiatric disorders, personality traits, and childhood traumatic events predicting incidence and persistence of chronic pain: results from the CoLaus|PsyCoLaus study.
Rouch I., Strippoli M.F., Dorey J.M., Ranjbar S., Laurent B., von Gunten A., Preisig M., 2023/09/01. Pain, 164 (9) pp. 2084-2092. Peer-reviewed.
Barriers to nurses performing physical assessments in rehabilitation care units: An observational study.
Da Veiga Gonçalves L., Latanioti M., Latif S., Verloo H., Pereira F., 2023/08. Journal of advanced nursing, 79 (8) pp. 3057-3068. Peer-reviewed.
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Shi L., Xu J., Green R., Wretlind A., Homann J., Buckley N.J., Tijms B.M., Vos SJB, Lill C.M., Kate M.T. et al., 2023/08. Alzheimer's & dementia, 19 (8) pp. 3350-3364. Peer-reviewed.
Is Clozapine-induced Weight Gain Dose-dependent? Results From a Prospective Cohort Study.
Piras M., Chahma J., Ranjbar S., Laaboub N., Grosu C., Plessen K.J., von Gunten A., Conus P., Eap C.B., 2023/07/04. Schizophrenia bulletin, 49 (4) pp. 944-952. Peer-reviewed.
 
Stability of the Subtypes of Major Depressive Disorder in Older Adults and the Influence of Mild Cognitive Impairment on the Stability.
Moyano B.P., Strippoli M.F., Ranjbar S., Vandeleur C.L., Vaucher J., Preisig M., von Gunten A., 2023/07. The American journal of geriatric psychiatry, 31 (7) pp. 503-513. Peer-reviewed.
Plant sterols and cholesterol metabolism are associated with five-year cognitive decline in the elderly population.
Clark C., Gholam M., Zullo L., Kerksiek A., Castelao E., von Gunten A., Preisig M., Lütjohann D., Popp J., 2023/06/16. iScience, 26 (6) p. 106740. Peer-reviewed.
Identification of four novel loci associated with psychotropic drug-induced weight gain in a Swiss psychiatric longitudinal study: A GWAS analysis.
Sjaarda J., Delacrétaz A., Dubath C., Laaboub N., Piras M., Grosu C., Vandenberghe F., Crettol S., Ansermot N., Gamma F. et al., 2023/06. Molecular psychiatry, 28 (6) pp. 2320-2327. Peer-reviewed.
Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits.
Küçükali F., Neumann A., Van Dongen J., De Pooter T., Joris G., De Rijk P., Ohlei O., Dobricic V., Bos I., Vos SJB et al., 2023/06. Alzheimer's & dementia, 19 (6) pp. 2317-2331. Peer-reviewed.
Do Adult Attachment Style or Personality Mediate the Relationship Between Childhood Maltreatment and Late-Life Depression in Poor Communities?
Gomes Jardim G.B., Gomes I., Mehdi G., Ranjbar S., Engroff P., Santos M.A., Neto A.C., von Gunten A., 2023/05. Journal of geriatric psychiatry and neurology, 36 (3) pp. 246-253. Peer-reviewed.
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease.
European Alzheimer's & Dementia Biobank Mendelian Randomization (EADB-MR) Collaboration, Luo J., Thomassen J.Q., Bellenguez C., Grenier-Boley B., de Rojas I., Castillo A., Parveen K., Küçükali F., Nicolas A. et al., 2023/05/01. JAMA network open, 6 (5) pp. e2313734. Peer-reviewed.
Music and autobiographical memory: A new experimental protocol.
Centomo F., Wyttenbach I.M., Bencivenni A., Raglio A., 2023/05. Psychogeriatrics, 23 (3) pp. 547-549. Peer-reviewed.
Climate Change, Environmental Health, and Challenges for Nursing Discipline.
Portela Dos Santos O., Melly P., Joost S., Verloo H., 2023/04/28. International journal of environmental research and public health, 20 (9) p. 5682. Peer-reviewed.
Obstructive sleep apnoea and 5-year cognitive decline in the elderly.
Marchi N.A., Solelhac G., Berger M., Haba-Rubio J., Gosselin N., Vollenweider P., Marques-Vidal P., Popp J., von Gunten A., Preisig M. et al., 2023/04. The European respiratory journal, 61 (4) p. 2201621. Peer-reviewed.
Standards de qualité en psychiatrie de la personne âgée [Qualitätsstandards in der Alterspsychiatrie]
Klöppel S., von Gunten A., Georgescu D., 2023/04. Praxis, 112 (5-6) pp. 1-7. Peer-reviewed.
Personnes âgées victimes de violence communautaire : étude descriptive et rétrospective de victimes ayant consulté à l'Unité de médecine des violences du CHUV, Suisse
Rybisar Van Dyke M., De Puy J., von Gunten A., Romain-Glassey N., 2023/03. La Revue de Médecine Légale, 14 (1) p. 100374.
Polysémie de l’agitation chez le sujet dément [Polysemy of agitation in dementia]
Schuster J.P., Santos Z., Von Gunten A., 2023/03/01. Revue medicale suisse, 19 (816) pp. 426-429.
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas I., Moreno-Grau S., Tesi N., Grenier-Boley B., Andrade V., Jansen I.E., Pedersen N.L., Stringa N., Zettergren A., Hernández I. et al., 2023/02/09. Nature communications, 14 (1) p. 716. Peer-reviewed.
An Intervention Program to Reduce Medication-Related Problems Among Polymedicated Home-Dwelling Older Adults (OptiMed): Protocol for a Pre-Post, Multisite, Pilot, and Feasibility Study.
Pereira F., Dixe MDA, Gonçalves Pereira S., Meyer-Massetti C., Verloo H., 2023/01/25. JMIR research protocols, 12 pp. e39130. Peer-reviewed.
Patterns of Medication Management and Associated Medical and Clinical Features among Home-Dwelling Older Adults: A Cross-Sectional Study in Central Portugal.
Dixe MDA, Pinho J., Pereira F., Verloo H., Meyer-Massetti C., Pereira S.G., 2023/01/17. International journal of environmental research and public health, 20 (3) p. 1701. Peer-reviewed.
Evolutions of Metabolic Parameters Following Switches of Psychotropic Drugs: A Longitudinal Cohort Study.
Piras M., Ranjbar S., Laaboub N., Grosu C., Gamma F., Plessen K.J., von Gunten A., Conus P., Eap C.B., 2023/01/03. Schizophrenia bulletin, 49 (1) pp. 24-33. Peer-reviewed.
 
Blood plasma protein profiles of neuropsychiatric symptoms and related cognitive decline in older people.
Rabl M., Clark C., Dayon L., Bowman G.L., Popp J., 2023/01. Journal of neurochemistry, 164 (2) pp. 242-254. Peer-reviewed.
Network analysis of the associations between personality traits, cognitive functioning, and inflammatory markers in elderly individuals without dementia.
Bastelica T., Lespine L.F., Rouch I., Tadri M., Dorey J.M., Strippoli M.F., d'Amato T., von Gunten A., Preisig M., Rey R., 2023. Frontiers in aging neuroscience, 15 p. 1093323. Peer-reviewed.
Persisting neuropsychiatric symptoms, Alzheimer's disease, and cerebrospinal fluid cortisol and dehydroepiandrosterone sulfate.
Ouanes S., Rabl M., Clark C., Kirschbaum C., Popp J., 2022/12/19. Alzheimer's research & therapy, 14 (1) p. 190. Peer-reviewed.
Biomarqueurs des pathologies neurodégénératives dans le diagnostic des troubles cognitifs - Revue et recommandations de Swiss Memory Clinics [Biomarkers for the diagnosis of cognitive impairment - Recommendations from the Swiss Memory Clinics]
Popp J., Georgescu D., Bürge M., Mundwiler-Pachlatko E., Bernasconi L., Felbecker A., 2022/12/14. Revue medicale suisse, 18 (808) pp. 2400-2405. Peer-reviewed.
Wish to Die Among Residents of Swiss Long-Term Care Facilities: A Multisite Cross-Sectional Study.
Rubli Truchard E., Monod S., Bula C.J., Dürst A.V., Levorato A., Mazzocato C., Münzer T., Pasquier J., Quadri P., Rochat E. et al., 2022/12. Journal of the American Medical Directors Association, 23 (12) pp. 1935-1941. Peer-reviewed.
Effectiveness of Educational Interventions to Increase Skills in Evidence-Based Practice among Nurses: The EDITcare Systematic Review.
Portela Dos Santos O., Melly P., Hilfiker R., Giacomino K., Perruchoud E., Verloo H., Pereira F., 2022/11/02. Healthcare, 10 (11). Peer-reviewed.
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
Jansen I.E., van der Lee S.J., Gomez-Fonseca D., de Rojas I., Dalmasso M.C., Grenier-Boley B., Zettergren A., Mishra A., Ali M., Andrade V. et al., 2022/11. Acta neuropathologica, 144 (5) pp. 821-842. Peer-reviewed.
Characteristics of subjective cognitive decline associated with amyloid positivity.
Janssen O., Jansen W.J., Vos SJB, Boada M., Parnetti L., Gabryelewicz T., Fladby T., Molinuevo J.L., Villeneuve S., Hort J. et al., 2022/10. Alzheimer's & dementia, 18 (10) pp. 1832-1845. Peer-reviewed.
Recommandations pour la prévention, le diagnostic et la thérapie des addictions à l’âge avancé [Recommendations for the prevention, diagnosis, and therapy of addiction in the elderly]
Popp J., Fuchs A., Hemmeter U., Ibach P.B., Indermaur E., Klöppel S., Laimbacher S., Latanioti M., Leyhe T., Lötscher C. et al., 2022/09/28. Revue medicale suisse, 18 (797) pp. 1817-1824. Peer-reviewed.
Consequences of Nurse Presenteeism in Switzerland and Portugal and Strategies to Minimize It: A Qualitative Study.
Pereira F., Querido A., Verloo H., Bieri M., Laranjeira C., 2022/09/25. Healthcare, 10 (10) p. 1871. Peer-reviewed.
A social network analysis to explore collaborative practice in home care: research protocol.
Schorderet C., Bastiaenen CHG, Verloo H., de Bie R.A., Allet L., 2022/09/19. BMC health services research, 22 (1) p. 1174. Peer-reviewed.
 
Qualitätsstandards in der Alterspsychiatrie [Quality Standards in Old Age Psychiatry]
Klöppel S., Gunten A.V., Georgescu D., 2022/09. Praxis, 111 (12) pp. 660-666. Peer-reviewed.
Utilisation de la kétamine en psychiatrie : mise à jour [Use of ketamine in psychiatry: an update]
Clerc M.T., Rosenhagen-Lapoirie M., Von Gunten A., 2022/08/31. Revue medicale suisse, 18 (793) pp. 1626-1629. Peer-reviewed.
Home-Dwelling Older Adults' Day-to-Day Community Interactions: A Qualitative Study.
Perruchoud E., von Gunten A., Ferreira T., Queirós A.M., Verloo H., 2022/08/12. Geriatrics, 7 (4) p. 82. Peer-reviewed.
Cohort Profile: The Lausanne cohort 65+ (Lc65+).
Henchoz Y., Blanco J.M., Fustinoni S., Nanchen D., Büla C., Seematter-Bagnoud L., von Gunten A., Santos-Eggimann B., 2022/08/10. International journal of epidemiology, 51 (4) pp. e156-e166. Peer-reviewed.
Contributing Factors of Presenteeism among Portuguese and Swiss Nurses: A Qualitative Study Using Focus Groups.
Laranjeira C., Pereira F., Querido A., Bieri M., Verloo H., 2022/07/21. International journal of environmental research and public health, 19 (14) p. 8844. Peer-reviewed.
 
Association between Big Five personality factors and medication adherence in the elderly.
Linkievicz N.M., Sgnaolin V., Engroff P., Behr Gomes Jardim G., Cataldo A., 2022/07/08. Trends in psychiatry and psychotherapy, 44 pp. e20200143. Peer-reviewed.
 
Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.
Le Guen Y., Belloy M.E., Grenier-Boley B., de Rojas I., Castillo-Morales A., Jansen I., Nicolas A., Bellenguez C., Dalmasso C., Küçükali F. et al., 2022/07/01. JAMA neurology, 79 (7) pp. 652-663. Peer-reviewed.
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology.
Delvenne A., Gobom J., Tijms B., Bos I., Reus L.M., Dobricic V., Kate M.T., Verhey F., Ramakers I., Scheltens P. et al., 2022/06/14. Alzheimer's & dementia, 19 (3) pp. 807-820. Peer-reviewed.
 
Effects of psychotropic switches on weight change: a prospective cohort study
Piras M., Ranjbar S., Dubath C., Laaboub N., Grosu C., Gamma F., Von Plessen K., Von Gunten A., Conus P., Eap C., 2022/06. pp. S731-S731 dans European Psychiatry.
Systemic and central nervous system neuroinflammatory signatures of neuropsychiatric symptoms and related cognitive decline in older people.
Clark C., Richiardi J., Maréchal B., Bowman G.L., Dayon L., Popp J., 2022/05/28. Journal of neuroinflammation, 19 (1) p. 127. Peer-reviewed.
Insomnia disorders are associated with increased cardiometabolic disturbances and death risks from cardiovascular diseases in psychiatric patients treated with weight-gain-inducing psychotropic drugs: results from a Swiss cohort.
Laaboub N., Dubath C., Ranjbar S., Sibailly G., Grosu C., Piras M., Délessert D., Richard-Lepouriel H., Ansermot N., Crettol S. et al., 2022/05/17. BMC psychiatry, 22 (1) p. 342. Peer-reviewed.
Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Visser P.J., Reus L.M., Gobom J., Jansen I., Dicks E., van der Lee S.J., Tsolaki M., Verhey FRJ, Popp J., Martinez-Lage P. et al., 2022/05/13. Molecular neurodegeneration, 17 (1) p. 37. Peer-reviewed.
Social Isolation and Loneliness among Near-Centenarians and Centenarians: Results from the Fordham Centenarian Study.
Zaccaria D., Cavalli S., Masotti B., Gomes Da Rocha C., von Gunten A., Jopp D.S., 2022/05/13. International journal of environmental research and public health, 19 (10) p. 5940. Peer-reviewed.
Daily Dose Effects of Risperidone on Weight and Other Metabolic Parameters: A Prospective Cohort Study.
Piras M., Dubath C., Gholam M., Laaboub N., Grosu C., Gamma F., Solida A., Plessen K.J., von Gunten A., Conus P. et al., 2022/05/09. The Journal of clinical psychiatry, 83 (4) pp. 21m14110. Peer-reviewed.
 
Healthcare use for major depressive disorders among middle-aged and older adults in the community.
Schuster J.P., Strippoli M.F., Hoertel N., Marques-Vidal P., Vandeleur C.L., Limosin F., Preisig M., von Gunten A., 2022/05. Social psychiatry and psychiatric epidemiology, 57 (5) pp. 953-961. Peer-reviewed.
 
Long-term stability and age-dependence of six regulatory serum proteins.
Menne F., Schipke C.G., Clark C., Popp J., 2022/05. Biomarkers in medicine, 16 (7) pp. 511-521. Peer-reviewed.
New insights into the genetic etiology of Alzheimer's disease and related dementias.
Bellenguez C., Küçükali F., Jansen I.E., Kleineidam L., Moreno-Grau S., Amin N., Naj A.C., Campos-Martin R., Grenier-Boley B., Andrade V. et al., 2022/04. Nature genetics, 54 (4) pp. 412-436. Peer-reviewed.
Olanzapine-associated dose-dependent alterations for weight and metabolic parameters in a prospective cohort.
Schoretsanitis G., Dubath C., Grosu C., Piras M., Laaboub N., Ranjbar S., Ansermot N., Crettol S., Vandenberghe F., Gamma F. et al., 2022/04. Basic & clinical pharmacology & toxicology, 130 (4) pp. 531-541. Peer-reviewed.
Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation.
Neumann A., Küçükali F., Bos I., Vos SJB, Engelborghs S., De Pooter T., Joris G., De Rijk P., De Roeck E., Tsolaki M. et al., 2022/04. Molecular psychiatry, 27 (4) pp. 1990-1999. Peer-reviewed.
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Visser P.J., Reus L.M., Gobom J., Jansen I., Dicks E., van der Lee S.J., Tsolaki M., Verhey FRJ, Popp J., Martinez-Lage P. et al., 2022/03/28. Molecular neurodegeneration, 17 (1) p. 27. Peer-reviewed.
Cerebrospinal Fluid Proteome Alterations Associated with Neuropsychiatric Symptoms in Cognitive Decline and Alzheimer's Disease.
Mroczek M., Clark C., Dayon L., Bowman G.L., Popp J., 2022/03/18. Cells, 11 (6) p. 1030. Peer-reviewed.
Unplanned nursing home admission among discharged polymedicated older inpatients: a single-centre, registry-based study in Switzerland.
Pereira F., Verloo H., von Gunten A., Del Río Carral M., Meyer-Massetti C., Martins M.M., Wernli B., 2022/03/04. BMJ open, 12 (3) pp. e057444. Peer-reviewed.
 
Le psychiatre comme « gatekeeper » : une étude qualitative sur le rôle du psychiatre dans les demandes de suicide assisté
Serra A.L., Stiefel F., Bourquin C., 2022/03/01. Geriatrie et psychologie neuropsychiatrie du vieillissement, 20 (1) pp. 111-120. Peer-reviewed.
 
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
Jansen W.J., Janssen O., Tijms B.M., Vos SJB, Ossenkoppele R., Visser P.J., Amyloid Biomarker Study Group, Aarsland D., Alcolea D., Altomare D. et al., 2022/03/01. JAMA neurology, 79 (3) pp. 228-243. Peer-reviewed.
 
Contributing factors to heterogeneity in the timing of the onset of major depressive episode: Results from a national study.
Rep C., Peyre H., Sánchez-Rico M., Blanco C., Dosquet M., Schuster J.P., Limosin F., Hoertel N., 2022/02/15. Journal of affective disorders, 299 pp. 585-595. Peer-reviewed.
 
Biomarker in der Diagnostik kognitiver Störungen – Empfehlungen der Swiss Memory Clinics [Biomarkers for the diagnosis of cognitive impairment - Recommendations from the Swiss Memory Clinics]
Popp J., Georgescu D., Bürge M., Mundwiler-Pachlatko E., Bernasconi L., Felbecker A., 2022. Praxis, 111 (13) pp. 738-744. Peer-reviewed.
Cerebrospinal Fluid Cortisol and Dehydroepiandrosterone Sulfate, Alzheimer's Disease Pathology, and Cognitive Decline.
Ouanes S., Clark C., Richiardi J., Maréchal B., Lewczuk P., Kornhuber J., Kirschbaum C., Popp J., 2022. Frontiers in aging neuroscience, 14 p. 892754. Peer-reviewed.
Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition.
Wesenhagen KEJ, Gobom J., Bos I., Vos SJB, Martinez-Lage P., Popp J., Tsolaki M., Vandenberghe R., Freund-Levi Y., Verhey F. et al., 2022. Alzheimer's & dementia, 14 (1) pp. e12286. Peer-reviewed.
Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset.
Homann J., Osburg T., Ohlei O., Dobricic V., Deecke L., Bos I., Vandenberghe R., Gabel S., Scheltens P., Teunissen C.E. et al., 2022. Frontiers in aging neuroscience, 14 p. 840651. Peer-reviewed.
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks.
Zhang Y., Ghose U., Buckley N.J., Engelborghs S., Sleegers K., Frisoni G.B., Wallin A., Lleó A., Popp J., Martinez-Lage P. et al., 2022. Frontiers in aging neuroscience, 14 p. 1040001. Peer-reviewed.
The promise of multi-omics approaches to discover biological alterations with clinical relevance in Alzheimer's disease.
Clark C., Rabl M., Dayon L., Popp J., 2022. Frontiers in aging neuroscience, 14 p. 1065904. Peer-reviewed.
The Impact of Nursing Staffs' Working Conditions on the Quality of Care Received by Older Adults in Long-Term Residential Care Facilities: A Systematic Review of Interventional and Observational Studies.
Perruchoud E., Weissbrodt R., Verloo H., Fournier C.A., Genolet A., Rosselet Amoussou J., Hannart S., 2021/12/28. Geriatrics, 7 (1) p. 6. Peer-reviewed.
Sex-Specific Metabolic Pathways Were Associated with Alzheimer's Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort.
Xu J., Green R., Kim M., Lord J., Ebshiana A., Westwood S., Baird A.L., Nevado-Holgado A.J., Shi L., Hye A. et al., 2021/11/03. Biomedicines, 9 (11) p. 1610. Peer-reviewed.
Effect of Quetiapine, from Low to High Dose, on Weight and Metabolic Traits: Results from a Prospective Cohort Study.
Dubath C., Piras M., Gholam M., Laaboub N., Grosu C., Sentissi O., Gamma F., Solida A., von Gunten A., Conus P. et al., 2021/11. Pharmacopsychiatry, 54 (6) pp. 279-286. Peer-reviewed.
Metabolomic alteration induced by psychotropic drugs: Short-term metabolite profile as a predictor of weight gain evolution.
Lenski M., Sidibé J., Gholam M., Hennart B., Dubath C., Augsburger M., von Gunten A., Conus P., Allorge D., Thomas A. et al., 2021/11. Clinical and translational science, 14 (6) pp. 2544-2555. Peer-reviewed.
Correction: Socio-economic position as a moderator of cardiometabolic outcomes in patients receiving psychotropic treatment associated with weight gain: results from a prospective 12-month inception cohort study and a large population-based cohort.
Dubath C., Gholam-Rezaee M., Sjaarda J., Levier A., Saigi-Morgui N., Delacrétaz A., Glatard A., Panczak R., Correll C.U., Solida A. et al., 2021/10/07..
 
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels.
Hong S., Dobricic V., Ohlei O., Bos I., Vos SJB, Prokopenko D., Tijms B.M., Andreasson U., Blennow K., Vandenberghe R. et al., 2021/10. Alzheimer's & dementia, 17 (10) pp. 1628-1640. Peer-reviewed.
Functional Status among Polymedicated Geriatric Inpatients at Discharge: A Population-Based Hospital Register Analysis.
Pereira F., Wernli B., von Gunten A., Carral MDR, Martins M.M., Verloo H., 2021/09/03. Geriatrics, 6 (3) p. 86. Peer-reviewed.
 
Replication study of plasma proteins relating to Alzheimer's pathology.
Shi L., Winchester L.M., Westwood S., Baird A.L., Anand S.N., Buckley N.J., Hye A., Ashton N.J., Bos I., Vos SJB et al., 2021/09. Alzheimer's & dementia, 17 (9) pp. 1452-1464. Peer-reviewed.
Using Living Labs to Explore Needs and Solutions for Older Adults With Dementia: Scoping Review.
Verloo H., Lorette A., Rosselet Amoussou J., Gillès de Pélichy E., Matos Queirós A., von Gunten A., Perruchoud E., 2021/08/19. JMIR aging, 4 (3) pp. e29031. Peer-reviewed.
CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals.
Tijms B.M., Gobom J., Teunissen C., Dobricic V., Tsolaki M., Verhey F., Popp J., Martinez-Lage P., Vandenberghe R., Lleó A. et al., 2021/08/02. Proteomes, 9 (3) p. 36. Peer-reviewed.
Does Cognitive Functioning Predict Chronic Pain in Older Adult? Results From the CoLaus|PsyCoLaus Longitudinal Study.
Rouch I., Dorey J.M., Strippoli M.F., Gholam M., Marques-Vidal P., Laurent B., von Gunten A., Preisig M., 2021/08. The journal of pain, 22 (8) pp. 905-913. Peer-reviewed.
 
Factors associated with subjective cognitive decline in dementia-free older adults-A population-based study.
Zullo L., Clark C., Gholam M., Castelao E., von Gunten A., Preisig M., Popp J., 2021/08. International journal of geriatric psychiatry, 36 (8) pp. 1188-1196. Peer-reviewed.
 
Late-onset and nonlate-onset schizophrenia: A comparison of clinical characteristics in a multicenter study.
Abou Kassm S., Limosin F., Naja W., Vandel P., Sánchez-Rico M., Alvarado J.M., von Gunten A., Hoertel N., CSA Study group, 2021/08. International journal of geriatric psychiatry, 36 (8) pp. 1204-1215. Peer-reviewed.
Risk of 30-day hospital readmission associated with medical conditions and drug regimens of polymedicated, older inpatients discharged home: a registry-based cohort study.
Pereira F., Verloo H., Zhivko T., Di Giovanni S., Meyer-Massetti C., von Gunten A., Martins M.M., Wernli B., 2021/07/14. BMJ open, 11 (7) pp. e052755. Peer-reviewed.
Valproate is associated with early decrease of high-density lipoprotein cholesterol levels in the psychiatric population.
Delacrétaz A., Glatard A., Dubath C., Gholam M., Gamma F., von Gunten A., Conus P., Eap C.B., 2021/07. Basic and clinical pharmacology and toxicology, 129 (1) pp. 26-35. Peer-reviewed.
Socio-economic position as a moderator of cardiometabolic outcomes in patients receiving psychotropic treatment associated with weight gain: results from a prospective 12-month inception cohort study and a large population-based cohort.
Dubath C., Gholam-Rezaee M., Sjaarda J., Levier A., Saigi-Morgui N., Delacrétaz A., Glatard A., Panczak R., Correll C.U., Solida A. et al., 2021/06/26. Translational psychiatry, 11 (1) p. 360. Peer-reviewed.
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas I., Moreno-Grau S., Tesi N., Grenier-Boley B., Andrade V., Jansen I.E., Pedersen N.L., Stringa N., Zettergren A., Hernández I. et al., 2021/06/07. Nature communications, 12 (1) p. 3417. Peer-reviewed.
 
The power of personality in successful ageing: a comprehensive review of larger quantitative studies.
Pocnet C., Popp J., Jopp D., 2021/06. European Journal of Ageing, 18 (2) pp. 269-285. Peer-reviewed.
Temporal trajectory of brain tissue property changes induced by electroconvulsive therapy.
Gyger L., Ramponi C., Mall J.F., Swierkosz-Lenart K., Stoyanov D., Lutti A., von Gunten A., Kherif F., Draganski B., 2021/05/15. NeuroImage, 232 p. 117895. Peer-reviewed.
Presenteeism Among Nurses in Switzerland and Portugal and Its Impact on Patient Safety and Quality of Care: Protocol for a Qualitative Study.
Pereira F., Querido A.I., Bieri M., Verloo H., Laranjeira C.A., 2021/05/13. JMIR research protocols, 10 (5) pp. e27963. Peer-reviewed.
Transforming a Patient Registry Into a Customized Data Set for the Advanced Statistical Analysis of Health Risk Factors and for Medication-Related Hospitalization Research: Retrospective Hospital Patient Registry Study.
Taushanov Z., Verloo H., Wernli B., Di Giovanni S., von Gunten A., Pereira F., 2021/05/11. JMIR medical informatics, 9 (5) pp. e24205. Peer-reviewed.
 
Why Centenarians' Depressive Symptoms Must Become a Priority for Nurses.
Gomes da Rocha C., von Gunten A., Jopp D., Ribeiro O., Verloo H., 2021/05. Journal of the American Medical Directors Association, 22 (5) pp. 1118-1119. Peer-reviewed.
An integrative multi-omics approach reveals new central nervous system pathway alterations in Alzheimer's disease.
Clark C., Dayon L., Masoodi M., Bowman G.L., Popp J., 2021/04/01. Alzheimer's research & therapy, 13 (1) p. 71. Peer-reviewed.
Gradient of electro-convulsive therapy's antidepressant effects along the longitudinal hippocampal axis.
Gyger L., Regen F., Ramponi C., Marquis R., Mall J.F., Swierkosz-Lenart K., von Gunten A., Toni N., Kherif F., Heuser I. et al., 2021/03/29. Translational psychiatry, 11 (1) p. 191. Peer-reviewed.
Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer's disease pathology and clinical disease progression.
Clark C., Lewczuk P., Kornhuber J., Richiardi J., Maréchal B., Karikari T.K., Blennow K., Zetterberg H., Popp J., 2021/03/25. Alzheimer's research & therapy, 13 (1) p. 65. Peer-reviewed.
 
Facilitators and barriers in implementing clinical nursing assessment in mental health care for older people: A multimethod approach.
Berthoud L., Turcotte M., Dzemaili S., Ducraux D., Zumstein-Shaha M., Ortoleva Bucher C., 2021/03. Nursing & health sciences, 23 (1) pp. 208-218. Peer-reviewed.
 
Generalizability of pharmacologic and psychotherapy trial results for late-life unipolar depression.
Hoertel N., Rotenberg L., Schuster J.P., Blanco C., Lavaud P., Hanon C., Hozer F., Teruel E., Manetti A., Costemale-Lacoste J.F. et al., 2021/02. Aging & mental health, 25 (2) pp. 367-377. Peer-reviewed.
Psychiatrie [Psychiatry]
Khazaal Y., Elowe J., Kloucek P., Preisig M., Tadri M., Vandeleur C., Vandenberghe F., Verloo H., Ros T., Von Gunten A., 2021/01/13. Revue medicale suisse, 17 (720-1) pp. 85-89.
Assessment of cognitive screening tests as predictors of driving cessation: A prospective cohort study of a median 4-year follow-up.
Kokkinakis I., Vaucher P., Cardoso I., Favrat B., 2021. PloS one, 16 (8) pp. e0256527. Peer-reviewed.
Associations Between High Plasma Methylxanthine Levels, Sleep Disorders and Polygenic Risk Scores of Caffeine Consumption or Sleep Duration in a Swiss Psychiatric Cohort.
Laaboub N., Gholam M., Sibailly G., Sjaarda J., Delacrétaz A., Dubath C., Grosu C., Piras M., Ansermot N., Crettol S. et al., 2021. Frontiers in psychiatry, 12 p. 756403. Peer-reviewed.
 
Cholesterol metabolites and plant sterols in cerebrospinal fluid are associated with Alzheimer's cerebral pathology and clinical disease progression.
Jahn T., Clark C., Kerksiek A., Lewczuk P., Lütjohann D., Popp J., 2021/01. The Journal of steroid biochemistry and molecular biology, 205 p. 105785. Peer-reviewed.
Empfehlungen für die Diagnostik und Therapie psychotischer Erkrankungen im Alter [Recommendations for the Diagnosis and Therapy of Psychotic Disorders in the Elderly]
Klöppel S., Savaskan E., Annoni J.M., Berruex J.L., Bohli L., Eder M., Hemmeter U., Hirsbrunner T., Leyhe T., Neyenhuys A. et al., 2021. Praxis, 110 (14) pp. 816-825. Peer-reviewed.
 
Older People's Health-Related Behaviors: Evidence from Three Cohorts of the Lc65+ Study.
Seematter-Bagnoud L., Santos-Eggimann B., Nanchen D., Blanco J.M., Büla C., von Gunten A., Démonet J.F., Henchoz Y., 2021. Behavioral medicine, 47 (3) pp. 246-250. Peer-reviewed.
Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies.
Shi L., Buckley N.J., Bos I., Engelborghs S., Sleegers K., Frisoni G.B., Wallin A., Lléo A., Popp J., Martinez-Lage P. et al., 2021. Frontiers in aging neuroscience, 13 p. 712545. Peer-reviewed.
Psychiatrie [Psychiatry]
Khazaal Yasser, Elowe Julien, Kloucek Petr, Preisig Martin, Tadri Myriam, Vandeleur Caroline, Vandenberghe Frederik, Verloo Henk, Ros Tomas, Von Guntenb Armin, 2021. Revue Médicale Suisse, 17 (720-21) pp. 85-89. Peer-reviewed.
The Forgotten Psychopathology of Depressed Long-Term Care Facility Residents: A Call for Evidence-Based Practice.
Matos Queirós A., von Gunten A., Martins M., Wellens NIH, Verloo H., 2021. Dementia and geriatric cognitive disorders extra, 11 (1) pp. 38-44. Peer-reviewed.
The geometric approach to human stress based on stress-related surrogate measures.
Kloucek P., von Gunten A., 2021. PloS one, 16 (1) pp. e0219414. Peer-reviewed.
 
Determinants of subjective cognitive decline in dementia‐free older adults: A population‐based study : Neuropsychology/Early detection of cognitive decline with neuropsychological tests
Zullo Leonardo, Clark Christopher, Popp Julius, 2020/12. Alzheimer's & Dementia, 16 (S6).
Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics.
Tijms B.M., Gobom J., Reus L., Jansen I., Hong S., Dobricic V., Kilpert F., Ten Kate M., Barkhof F., Tsolaki M. et al., 2020/12/01. Brain, 143 (12) pp. 3776-3792. Peer-reviewed.
Conference report: dementia research and care and its impact in Switzerland.
Leyhe T., Jucker M., Nef T., Sollberger M., Riese F., Haba-Rubio J., Verloo H., Lüthi R., Becker S., Popp J., 2020/11/30. Swiss medical weekly, 150 pp. w20376. Peer-reviewed.
Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset.
Hong S., Prokopenko D., Dobricic V., Kilpert F., Bos I., Vos SJB, Tijms B.M., Andreasson U., Blennow K., Vandenberghe R. et al., 2020/11/22. Translational psychiatry, 10 (1) p. 403. Peer-reviewed.
 
Cerebrospinal fluid total tau levels indicate aberrant neuronal plasticity in Alzheimer's disease.
Visser P.J., Reus L.M., Gobom J., Jansen I., Dicks E., Tsolaki M., Verhey FRJ, Popp J., Martinez-Lage P., Vandenberghe R. et al., 2020/11/03..
Réponses aux urgences psychiatriques auprès des patients âgés en crise vivant à domicile ou en EMS - Une expérience vaudoise
Gillès De Pélichy E., Ebbing K., Matos Queiros A., Von Gunten A., Cornu L., Verloo H., 2020/10/14. Revue medicale suisse, 16 (710) pp. 1945-1948. Peer-reviewed.
Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery-A Prospective, Observational Cohort Study.
Guenther U., Hoffmann F., Dewald O., Malek R., Brimmers K., Theuerkauf N., Putensen C., Popp J., 2020/10/03. Geriatrics, 5 (4) pp. E69. Peer-reviewed.
 
Salivary cortisol and five-year change in cognitive performance in non-demented elderly subjects: a population-based study.
Ouanes S., Castelao E., von Gunten A., Kuehner C., Preisig M., Popp J., 2020/10. Neurobiology of aging, 94 pp. 34-37. Peer-reviewed.
Perceptions About Technologies That Help Community-Dwelling Older Adults Remain at Home: Qualitative Study.
Verloo H., Kampel T., Vidal N., Pereira F., 2020/06/04. Journal of medical Internet research, 22 (6) pp. e17930. Peer-reviewed.
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.
Kleineidam L., Chouraki V., Próchnicki T., van der Lee S.J., Madrid-Márquez L., Wagner-Thelen H., Karaca I., Weinhold L., Wolfsgruber S., Boland A. et al., 2020/06. Acta neuropathologica, 139 (6) pp. 1025-1044. Peer-reviewed.
APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease.
Konijnenberg E., Tijms B.M., Gobom J., Dobricic V., Bos I., Vos S., Tsolaki M., Verhey F., Popp J., Martinez-Lage P. et al., 2020/05/27. Alzheimer's research & therapy, 12 (1) p. 65. Peer-reviewed.
Key role of MIF-related neuroinflammation in neurodegeneration and cognitive impairment in Alzheimer's disease.
Nasiri E., Sankowski R., Dietrich H., Oikonomidi A., Huerta P.T., Popp J., Al-Abed Y., Bacher M., 2020/04/17. Molecular medicine, 26 (1) p. 34. Peer-reviewed.
Contributing Factors to Heterogeneity in the Timing of the Onset of Nonfatal Suicidal Behavior: Results From a Nationally Representative Study.
Hoertel N., Sabatier J., Blanco C., Olfson M., Schuster J.P., Airagnes G., Peyre H., Limosin F., 2020/04/07. The Journal of clinical psychiatry, 81 (3) pp. 19m13017. Peer-reviewed.
 
Benzodiazepine use among older adults with schizophrenia spectrum disorder: prevalence and associated factors in a multicenter study
Schuster Jean-Pierre, Hoertel Nicolas, von Gunten Armin, Seigneurie Anne-Sophie, Limosin Frédéric, 2020/04. International Psychogeriatrics, 32 (4) pp. 441-451. Peer-reviewed.
Recognizing images: The role of motivational significance, complexity, social content, age, and gender.
Gomez P., von Gunten A., Danuser B., 2020/04. Scandinavian journal of psychology, 61 (2) pp. 183-194. Peer-reviewed.
Evaluation of Cardiometabolic Risk in a Large Psychiatric Cohort and Comparison With a Population-Based Sample in Switzerland.
Dubath C., Delacrétaz A., Glatard A., Vollenweider P., Preisig M., Richard-Lepouriel H., Hasler R., Gamma F., Solida A., Thonney J. et al., 2020/03/31. The Journal of clinical psychiatry, 81 (3) pp. 19m12796. Peer-reviewed.
A Comprehensive Scoping Review Protocol of Using Living Labs to Explore Needs and Solutions for Older Adults with Dementia
Verloo Henk, Lorette Adrien, Gomes da Rocha Carla, Amoussou Joëlle Rosselet, Gillès de Pélichy Estelle, Matos Queiros Alcina, Mendez Rubio Montserrat, von Gunten Armin, 2020/03. Smart Homecare Technology and TeleHealth, Volume 7 pp. 19-27. Peer-reviewed.
Amisulpride: Real-World Evidence of Dose Adaptation and Effect on Prolactin Concentrations and Body Weight Gain by Pharmacokinetic/Pharmacodynamic Analyses.
Glatard A., Guidi M., Delacrétaz A., Dubath C., Grosu C., Laaboub N., von Gunten A., Conus P., Csajka C., Eap C.B., 2020/03. Clinical pharmacokinetics, 59 (3) pp. 371-382. Peer-reviewed.
Epidemiology of at-risk alcohol use and associated comorbidities of interest among community-dwelling older adults: a protocol for a systematic review.
Latanioti M., Schuster J.P., Rosselet Amoussou J., Strippoli M.F., von Gunten A., Ebbing K., Verloo H., 2020/01/09. BMJ open, 10 (1) pp. e035481. Peer-reviewed.
Developing an Evidence-Based Nursing Handover Standard for a Multi-Site Public Hospital in Switzerland: Protocol for a Web-Based, Modified Delphi Study.
Tacchini-Jacquier N., de Waele E., Urben P., Turini P., Verloo H., 2020/01/08. JMIR research protocols, 9 (1) pp. e15910. Peer-reviewed.
 
Comité d’animation en Ehpad, importance fonctionnelle et enjeux [Entertainment committee in accommodation facilities for dependent elderly, functional importance and psychic stakes]
Pellerin J., Schuster J.P., 2020. Soins. Gerontologie, 25 (146) pp. 40-45. Peer-reviewed.
Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology.
Shi L., Winchester L.M., Liu B.Y., Killick R., Ribe E.M., Westwood S., Baird A.L., Buckley N.J., Hong S., Dobricic V. et al., 2020. Journal of Alzheimer's disease, 77 (3) pp. 1353-1368. Peer-reviewed.
 
Early-Stage Alzheimer's Disease Does Not Alter Pupil Responses to Colored Light Stimuli.
Kawasaki A., Ouanes S., Crippa S.V., Popp J., 2020. Journal of Alzheimer's disease, 75 (4) pp. 1273-1282. Peer-reviewed.
 
Neuroticism-Withdrawal and Neuroticism-Volatility Differently Influence the Risk of Neuropsychiatric Symptoms in Alzheimer's Disease.
Dorey J.M., Rouch I., Padovan C., Boublay N., Pongan E., Laurent B., PACO Group, von Gunten A., Krolak-Salmon P., 2020. Journal of Alzheimer's disease, 74 (1) pp. 79-89. Peer-reviewed.
 
Pharmacologie du sujet âgé
Eap Chin Bin, Sibailly Guibet, 2020. pp. 155-164 dans Clerc Marie-Thérèse, Mall Jean-Frédéric, von Gunten Armin (eds.) Vademecum de psychiatrie gériatrique chap. 1, RMS éditions, Médecine & Hygiène.
Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort.
Westwood S., Baird A.L., Anand S.N., Nevado-Holgado A.J., Kormilitzin A., Shi L., Hye A., Ashton N.J., Morgan A.R., Bos I. et al., 2020. Journal of Alzheimer's disease, 74 (1) pp. 213-225. Peer-reviewed.
Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients.
Delacrétaz A., Glatard A., Dubath C., Gholam-Rezaee M., Sanchez-Mut J.V., Gräff J., von Gunten A., Conus P., Eap C.B., 2019/12/26. Clinical epigenetics, 11 (1) p. 198. Peer-reviewed.
Relationship between childhood maltreatment and geriatric depression: the mediator effect of personality traits.
Gomes Jardim G.B., von Gunten A., da Silva Filho I.G., Ziegelmann P.K., Bumaguin D.B., Nogueira E.L., Engroff P., Neto A.C., 2019/12. International psychogeriatrics, 31 (12) pp. 1759-1767. Peer-reviewed.
Systemic and central nervous system metabolic alterations in Alzheimer's disease
van der Velpen Vera, Teav Tony, Gallart-Ayala Héctor, Mehl Florence, Konz Ioana, Clark Christopher, Oikonomidi Aikaterini, Peyratout Gwendoline, Henry Hugues, Delorenzi Mauro et al., 2019/12. Alzheimer's Research & Therapy, 11 (1). Peer-reviewed.
 
Systemic and central nervous system metabolic alterations in Alzheimer's disease.
van der Velpen V., Teav T., Gallart-Ayala H., Mehl F., Konz I., Clark C., Oikonomidi A., Peyratout G., Henry H., Delorenzi M. et al., 2019/11/28. Alzheimer's research & therapy, 11 (1) p. 93. Peer-reviewed.
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
Shi L., Westwood S., Baird A.L., Winchester L., Dobricic V., Kilpert F., Hong S., Franke A., Hye A., Ashton N.J. et al., 2019/11. Alzheimer's & dementia, 15 (11) pp. 1478-1488. Peer-reviewed.
Optimising medication management for polymedicated home-dwelling older adults with multiple chronic conditions: a mixed-methods study protocol.
Pereira F., Roux P., Santiago-Delefosse M., von Gunten A., Wernli B., Martins M.M., Verloo H., 2019/10/28. BMJ open, 9 (10) pp. e030030. Peer-reviewed.
Interventional psychiatry in the management of behavioural and psychological symptoms of dementia: a qualitative review.
Swierkosz-Lenart K., Mall J.F., von Gunten A., 2019/10/21. Swiss medical weekly, 149 pp. w20140. Peer-reviewed.
Eye gaze behavior during affective picture viewing: Effects of motivational significance, gender, age, and repeated exposure.
Gomez P., von Gunten A., Danuser B., 2019/09. Biological psychology, 146 p. 107713. Peer-reviewed.
Phenomenological contribution to understanding of vocally disruptive behaviour: A clinical case study in a patient with dementia.
Tible O., Mendez M., von Gunten A., 2019/09. International journal of geriatric psychiatry, 34 (9) pp. 1294-1300. Peer-reviewed.
Using a Triple Aim Approach to Implement "Less-is-More Together" and Smarter Medicine Strategies in an Interprofessional Outpatient Setting: Protocol for an Observational Study.
Lehky Hagen M., Julen R., Buchs P.A., Kaufmann A.L., Gaspoz J.M., Verloo H., 2019/07/18. JMIR research protocols, 8 (7) pp. e13896. Peer-reviewed.
Inflammatory biomarkers in Alzheimer's disease plasma.
Morgan A.R., Touchard S., Leckey C., O'Hagan C., Nevado-Holgado A.J., NIMA Consortium, Barkhof F., Bertram L., Blin O., Bos I. et al., 2019/06. Alzheimer's & dementia, 15 (6) pp. 776-787. Peer-reviewed.
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort.
Kim M., Snowden S., Suvitaival T., Ali A., Merkler D.J., Ahmad T., Westwood S., Baird A., Proitsi P., Nevado-Holgado A. et al., 2019/06. Alzheimer's & dementia, 15 (6) pp. 817-827. Peer-reviewed.
Medication Management Models for Polymedicated Home-Dwelling Older Adults With Multiple Chronic Conditions: Protocol of a Systematic Review.
Pereira F., Roux P., Rosselet Amoussou J., Martins M.M., von Gunten A., Verloo H., 2019/05/28. JMIR research protocols, 8 (5) pp. e13582. Peer-reviewed.
 
Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum.
Bos I., Vos S., Verhey F., Scheltens P., Teunissen C., Engelborghs S., Sleegers K., Frisoni G., Blin O., Richardson J.C. et al., 2019/05. Alzheimer's & dementia, 15 (5) pp. 644-654. Peer-reviewed.
 
Proteomes of Paired Human Cerebrospinal Fluid and Plasma: Relation to Blood-Brain Barrier Permeability in Older Adults.
Dayon L., Cominetti O., Wojcik J., Galindo A.N., Oikonomidi A., Henry H., Migliavacca E., Kussmann M., Bowman G.L., Popp J., 2019/03/01. Journal of proteome research, 18 (3) pp. 1162-1174. Peer-reviewed.
Do baby boomers feel healthier than earlier cohorts after retirement age? The Lausanne cohort Lc65+ study.
Henchoz Y., von Gunten A., Büla C., Seematter-Bagnoud L., Nanchen D., Démonet J.F., Blanco J.M., Santos-Eggimann B., 2019/02/19. BMJ open, 9 (2) pp. e025175. Peer-reviewed.
 
La relation aidant – aidé : la soutenir, toujours la soutenir
Schuster J.-P., Pellerin J., 2019/02. NPG Neurologie - Psychiatrie - Gériatrie, 19 (109) pp. 11-15.
A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort.
Stamate D., Kim M., Proitsi P., Westwood S., Baird A., Nevado-Holgado A., Hye A., Bos I., Vos SJB, Vandenberghe R. et al., 2019. Alzheimer's & dementia, 5 pp. 933-938. Peer-reviewed.
Associations between Frailty and Delirium among Older Patients Admitted to an Emergency Department.
Choutko-Joaquim S., Tacchini-Jacquier N., Pralong D'Alessio G., Verloo H., 2019. Dementia and geriatric cognitive disorders extra, 9 (2) pp. 236-249. Peer-reviewed.
Childhood adversity: A gateway to multimorbidity in older age?
Henchoz Y., Seematter-Bagnoud L., Nanchen D., Büla C., von Gunten A., Démonet J.F., Santos-Eggimann B., 2019. Archives of gerontology and geriatrics, 80 pp. 31-37. Peer-reviewed.
 
Délires et hallucinations
Pancrazi Marie-Pierre, Schuster Jean-Pierre, 2019. pp. 592-604 dans Belmin J., Chassagne P., Friocourt P. (eds.) Gériatrie pour le praticien chap. 66, Elsevier Masson.
Early Secure Attachment as a Protective Factor Against Later Cognitive Decline and Dementia.
Walsh E., Blake Y., Donati A., Stoop R., von Gunten A., 2019. Frontiers in aging neuroscience, 11 p. 161. Peer-reviewed.
High Cortisol and the Risk of Dementia and Alzheimer's Disease: A Review of the Literature.
Ouanes S., Popp J., 2019. Frontiers in aging neuroscience, 11 p. 43. Peer-reviewed.
 
Neurocognitive Disorders in Old Age: Alzheimer's Disease, Frontotemporal Dementia, Dementia with Lewy Bodies, and Prion and Infectious Diseases
von Gunten Armin, Nogueira Eduardo, Parmentier Henk, Gomes Irênio, 2019. pp. 251-298 dans Primary Care Mental Health in Older People chap. 21, Springer International Publishing.
Polypharmacy Among Home-Dwelling Older Adults: The Urgent Need for an Evidence-Based Medication Management Model.
Pereira F., von Gunten A., Rosselet Amoussou J., De Giorgi Salamun I., Martins M.M., Verloo H., 2019. Patient preference and adherence, 13 pp. 2137-2143. Peer-reviewed.
 
Preoperative Depression and Plasma Cortisol Levels as Predictors of Delirium after Cardiac Surgery
Eshmawey Mohamed, Arlt Sönke, Ledschbor-Frahnert Christine, Guenther Ulf, Popp Julius, 2019. Dementia and Geriatric Cognitive Disorders, 48 (3-4) pp. 207-214.
 
Structures médicosociales et sociales (institutionnalisation)
Schuster Jean-Pierre, Guillaumot Philippe, Pellerin Jérôme, 2019. pp. 544-554 dans Clément Jean-Pierre, Calvet Benjamin (eds.) Psychiatrie de la personne âgée chap. 49, Lavoisier.
Translation and Brazilian adaptation of the Relationship Scales Questionnaire (RSQ).
de Assis E.N., Loureiro F.S., Menta C., Nogueira E.L., da Silva Filho I.G., von Gunten A., Cataldo Neto A., 2019. Trends in psychiatry and psychotherapy, 41 (1) pp. 69-77. Peer-reviewed.
 
A global HILIC-MS approach to measure polar human cerebrospinal fluid metabolome: Exploring gender-associated variation in a cohort of elderly cognitively healthy subjects.
Gallart-Ayala H., Konz I., Mehl F., Teav T., Oikonomidi A., Peyratout G., van der Velpen V., Popp J., Ivanisevic J., 2018/12/11. Analytica chimica acta, 1037 pp. 327-337. Peer-reviewed.
 
Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults.
Bowman G.L., Dayon L., Kirkland R., Wojcik J., Peyratout G., Severin I.C., Henry H., Oikonomidi A., Migliavacca E., Bacher M. et al., 2018/12. Alzheimer's & dementia, 14 (12) pp. 1640-1650. Peer-reviewed.
LC-HRMS data as a result of untargeted metabolomic profiling of human cerebrospinal fluid.
Mehl F., Gallart-Ayala H., Konz I., Teav T., Oikonomidi A., Peyratout G., van der Velpen V., Popp J., Ivanisevic J., 2018/12. Data in brief, 21 pp. 1358-1362. Peer-reviewed.
The Effects of Hand Massage on Stress and Agitation Among People with Dementia in a Hospital Setting: A Pilot Study.
Schaub C., Von Gunten A., Morin D., Wild P., Gomez P., Popp J., 2018/12. Applied psychophysiology and biofeedback, 43 (4) pp. 319-332. Peer-reviewed.
Association Between Plasma Caffeine and Other Methylxanthines and Metabolic Parameters in a Psychiatric Population Treated With Psychotropic Drugs Inducing Metabolic Disturbances
Delacrétaz Aurélie, Vandenberghe Frederik, Glatard Anaïs, Levier Axel, Dubath Céline, Ansermot Nicolas, Crettol Séverine, Gholam-Rezaee Mehdi, Guessous Idris, Bochud Murielle et al., 2018/11/09. Frontiers in Psychiatry, 9.
Oxytocin receptor polymorphisms and attachment style in patients with cognitive impairment and affective symptoms
Tible Olivier , von Gunten Armin , 2018/11/09. Journal of behavioral neuroscience, 2 (1) pp. 1-6.
 
Effects of Psychiatric Disorders on Suicide Attempt: Similarities and Differences Between Older and Younger Adults in a National Cohort Study.
Pascal de Raykeer R., Hoertel N., Blanco C., Olfson M., Wall M., Seigneurie A.S., Schuster J.P., Lemogne C., von Gunten A., Limosin F., 2018/10/09. The Journal of clinical psychiatry, 79 (6) pp. NA. Peer-reviewed.
MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study.
Ten Kate M., Redolfi A., Peira E., Bos I., Vos S.J., Vandenberghe R., Gabel S., Schaeverbeke J., Scheltens P., Blin O. et al., 2018/09/27. Alzheimer's research & therapy, 10 (1) p. 100. Peer-reviewed.
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