University Centre of Legal Medicine

Laboratoire d'analyse du dopage (LAD) | Unité de génétique forensique (UGF) | Unité de médecine des violences (UMV) | Unité de médecine et psychologie du trafic (UMPT) | Unité de taphonomie forensique (SHIFT) | Unité de toxicologie et chimie forensique (UTCF) | Unité d'imagerie et anthropologie forensiques (UIAF) | Unité facultaire d'anatomie et de morphologie (UFAM) | Unité facultaire de toxicologie (UFT) | Unité romande de médecine forensique (URMF)
Publications | Phd and Masters theses

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44 publications

En préparation
SMYD3: a new regulator of the early steps of adipocyte differentiation
Gilardi Federica, Sajic Tatjana, Gasser Marie, Caputo Tiziana, Bararpour Nasim, Augsburger Marc, Walter Nadia, Hainard Alexander, Fracasso Tony, Thomas Aurelien.
[URN][DOI][serval:BIB_5680D6E6B9C7]
In press
 
Reference values for plasma and urine trace elements in a Swiss population-based cohort.
Perrais M., Trächsel B., Lenglet S., Pruijm M., Ponte B., Vogt B., Augsburger M., Rousson V., Bochud M., Thomas A. Clinical chemistry and laboratory medicine. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FF27C8C5A176]
2024
SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation.
Sajic T., Ferreira Gomes C.K., Gasser M., Caputo T., Bararpour N., Landaluce-Iturriria E., Augsburger M., Walter N., Hainard A., Lopez-Mejia I.C. et al., 2024/04. International journal of obesity, 48 (4) pp. 557-566. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_65FA0943DC42]
 
Effects of personal exposure to the oxidative potential of PM2.5 on oxidative stress biomarkers in pregnant women.
Marsal A., Sauvain J.J., Thomas A., Lyon-Caen S., Borlaza LJS, Philippat C., Jaffrezo J.L., Boudier A., Darfeuil S., Elazzouzi R. et al., 2024/02/10. The Science of the total environment, 911 p. 168475. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6AB0ACB53957]
 
Gonadotropin axis and semen quality in young Swiss men after cannabis consumption: Effect of chronicity and modulation by cannabidiol.
Zufferey F., Buitrago E., Rahban R., Senn A., Stettler E., Rudaz S., Nef S., Donzé N., Thomas A., Rossier M.F., 2024/01. Andrology, 12 (1) pp. 56-67. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7539EAD37016]
People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case-control study.
Frias M.A., Pagano S., Bararpour N., Sidibé J., Kamau F., Fétaud-Lapierre V., Hudson P., Thomas A., Lecour S., Strijdom H. et al., 2024. Frontiers in cardiovascular medicine, 11 p. 1343361. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3D1A08272D68]
2023
Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study.
de La Harpe R., Schoeler T., Thorball C.W., Thomas A., Kutalik Z., Vaucher J., 2023/12/13. BMC cardiovascular disorders, 23 (1) p. 611. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2C9E1FFFC502]
Arsenic induces metabolome remodeling in mature human adipocytes.
Gasser M., Lenglet S., Bararpour N., Sajic T., Vaucher J., Wiskott K., Augsburger M., Fracasso T., Gilardi F., Thomas A., 2023/12. Toxicology, 500 p. 153672. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_513BAB55CAFC]
Association of Trace Element Levels with Outcomes in Critically Ill COVID-19 Patients.
Wozniak H., Le Terrier C., Primmaz S., Suh N., Lenglet S., Thomas A., Vuilleumier N., Pagano S., de Watteville A., Stringhini S. et al., 2023/07/26. Nutrients, 15 (15) p. 3308. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FDCEE1759336]
Differentiating individuals through the chemical composition of their fingermarks.
Gorka M., Thomas A., Bécue A., 2023/05. Forensic science international, 346 p. 111645. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9BB5A84BACED]
 
Comparison of Dried Blood Spot and Microtube Techniques for Trace Element Quantification by ICP-MS.
Perrais M., Thomas A., Augsburger M., Lenglet S., 2023/03/21. Journal of analytical toxicology, 47 (2) pp. 175-181. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_987E10F0FE4C]
Blood proteome of acute intracranial hemorrhage in infant victims of abusive head trauma.
Wiskott K., Gilardi F., Hainard A., Sanchez J.C., Thomas A., Sajic T., Fracasso T., 2023/02. Proteomics, 23 (3-4) pp. e2200078. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_55A9C6918506]
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone.
Nunes C., Proença S., Ambrosini G., Pamies D., Thomas A., Kramer N.I., Zurich M.G., 2023. Frontiers in pharmacology, 14 p. 1248882. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5026E918AA69]
2022
Randomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods.
Joye T., Déglon J., Donzé N., Gilardi F., Sidibé J., Favrat B., Augsburger M., Thomas A., 2022/12/28. BMC public health, 22 (1) p. 2446. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C4890A2DF3E4]
Chemical composition of the fingermark residue: Assessment of the intravariability over one year using MALDI-MSI.
Gorka M., Thomas A., Bécue A., 2022/09. Forensic science international, 338 p. 111380. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_04910E6E854B]
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
Nunes C., Singh P., Mazidi Z., Murphy C., Bourguignon A., Wellens S., Chandrasekaran V., Ghosh S., Zana M., Pamies D. et al., 2022/06. Toxicology in vitro, 81 p. 105333. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FEAAC77037C3]
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots.
Magliocco G., Desmeules J., Samer C.F., Thomas A., Daali Y., 2022/06. Clinical and translational science, 15 (6) pp. 1482-1491. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9893853BA3FA]
 
Toxicity and Metabolomic Impact of Cobalt, Chromium, and Nickel Exposure on HepaRG Hepatocytes.
Bellouard M., Gasser M., Lenglet S., Gilardi F., Bararpour N., Augsburger M., Thomas A., Alvarez J.C., 2022/05/16. Chemical research in toxicology, 35 (5) pp. 807-816. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D07FD4606226]
 
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Sblano S., Cerchia C., Laghezza A., Piemontese L., Brunetti L., Leuci R., Gilardi F., Thomas A., Genovese M., Santi A. et al., 2022/05/05. European journal of medicinal chemistry, 235 p. 114240. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_174713AD57D2]
Creation of a Forensic Pathology Biobank in Switzerland: which issues and research opportunities?
Wiskott K., Gilardi F., Michaud K., Augsburger M., Castiglioni C., Carminati A., Grabherr S., Thomas A., Fracasso T., 2022/05. International journal of legal medicine, 136 (3) pp. 919-922. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E9953DCA1001]
Cadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes.
Gasser M., Lenglet S., Bararpour N., Sajic T., Wiskott K., Augsburger M., Fracasso T., Gilardi F., Thomas A., 2022/03/30. Toxicology, 470 p. 153153. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_39F3DD933D67]
Analyse systématique du GHB dans les échantillons biologiques : rapport de synthèse 2021
Augsburger M., Thomas A., Carron PN, 2022/01/01. 21, Unité de toxicologie et de chimie forensiques, Centre universitaire romand de médecine légale.
[URN][serval:BIB_6703A275EB24]
The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance.
Verouti S.N., Pujol-Giménez J., Bermudez-Lekerika P., Scherler L., Bhardwaj R., Thomas A., Lenglet S., Siegrist M., Hofstetter W., Fuster D.G. et al., 2022. Frontiers in physiology, 13 p. 912277. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F08CFA3A579C]
2021
Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity.
Magliocco G., Desmeules J., Matthey A., Quirós-Guerrero L.M., Bararpour N., Joye T., Marcourt L., Queiroz E.F., Wolfender J.L., Gloor Y. et al., 2021/12. British journal of pharmacology, 178 (23) pp. 4708-4725. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8116E84FC609]
Suspicion of driving under the influence of alcohol or drugs: Cross sectional analysis of drug prevalence in the context of the Swiss legislation.
Maurer J., Vergalito E., Prior A.F., Donzé N., Thomas A., Augsburger M., 2021/12. Forensic science international, 329 p. 111081. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DABAB3038547]
Metabolomic alteration induced by psychotropic drugs: Short-term metabolite profile as a predictor of weight gain evolution.
Lenski M., Sidibé J., Gholam M., Hennart B., Dubath C., Augsburger M., von Gunten A., Conus P., Allorge D., Thomas A. et al., 2021/11. Clinical and translational science, 14 (6) pp. 2544-2555. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B399E4FCFB6A]
Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice.
Schiffrin M., Winkler C., Quignodon L., Naldi A., Trötzmüller M., Köfeler H., Henry H., Parini P., Desvergne B., Gilardi F., 2021/09/15. International journal of molecular sciences, 22 (18) p. 9969. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_978B8840BE0C]
Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS.
Magliocco G., Le Bloc'h F., Thomas A., Desmeules J., Daali Y., 2021/09/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1181 p. 122938. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5CDFB8562D73]
Summary statistics for drugs and alcohol concentration recovered in post-mortem femoral blood in Western Switzerland.
Lefrancois E., Reymond N., Thomas A., Lardi C., Fracasso T., Augsburger M., 2021/08. Forensic science international, 325 p. 110883. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8C70B8F9DC3B]
Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects.
Nacher-Soler G., Lenglet S., Coelho M., Thomas A., Voruz F., Krause K.H., Senn P., Rousset F., 2021/07/31. Frontiers in cellular neuroscience, 15 p. 701783. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DDA30E86F8E4]
A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men.
Marin Bosch B., Bringard A., Logrieco M.G., Lauer E., Imobersteg N., Thomas A., Ferretti G., Schwartz S., Igloi K., 2021/07/13. Scientific reports, 11 (1) p. 14371. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E058F2816C67]
Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry.
Mueller F., Losacco G.L., Nicoli R., Guillarme D., Thomas A., Grata E., 2021/07/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1177 p. 122755. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7BB2CDC79102]
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Porcu E., Gilardi F., Darrous L., Yengo L., Bararpour N., Gasser M., Marques-Vidal P., Froguel P., Waeber G., Thomas A. et al., 2021/03/18. Scientific reports, 11 (1) p. 6197. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_31003871533C]
DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies.
Bararpour N., Gilardi F., Carmeli C., Sidibe J., Ivanisevic J., Caputo T., Augsburger M., Grabherr S., Desvergne B., Guex N. et al., 2021/03/11. Scientific reports, 11 (1) p. 5657. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C00E7D1EAE17]
Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland.
Mueller F., Bogdal C., Pfeiffer B., Andrello L., Ceschi A., Thomas A., Grata E., 2021/03. Forensic science international, 320 p. 110686. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5DA78D18783F]
The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker?
Magliocco G., Desmeules J., Bosilkovska M., Thomas A., Daali Y., 2021/02/20. Journal of personalized medicine, 11 (2) p. 150. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8186FF4285F1]
Three-Dimensional Quantification of Bone Mineral Density in the Distal Femur and Proximal Tibia Based on Computed Tomography: In Vitro Evaluation of an Extended Standardization Method.
Babel H., Omoumi P., Cosendey K., Cadas H., Jolles B.M., Favre J., 2021/01/05. Journal of clinical medicine, 10 (1) p. 160. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_71550A7DEB3F]
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Caputo T., Tran VDT, Bararpour N., Winkler C., Aguileta G., Trang KB, Giordano Attianese GMP, Wilson A., Thomas A., Pagni M. et al., 2021/01. Cellular and molecular life sciences, 78 (1) pp. 227-247. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_713DAFDC1C95]
Vascular-targeted micelles as a specific MRI contrast agent for molecular imaging of fibrin clots and cancer cells.
Vorobiev V., Adriouach S., Crowe L.A., Lenglet S., Thomas A., Chauvin A.S., Allémann E., 2021/01. European journal of pharmaceutics and biopharmaceutics, 158 pp. 347-358. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_612B428BDFF5]
2020
Identification of metabolomics biomarkers for type 2 diabetes: triangulating evidence from longitudinal and Mendelian randomization analyses
Porcu E., Gilardi F., Darrous L., Yengo L., Bararpour N., Gasser M., Vidal PM, Froguel P., Waeber G., Thomas A. et al., 2020/10/30..
[URN][DOI][serval:BIB_9A811092850F]
Effect of acute physical exercise on motor sequence memory.
Marin Bosch B., Bringard A., Logrieco MG, Lauer E., Imobersteg N., Thomas A., Ferretti G., Schwartz S., Igloi K., 2020/09/18. Scientific reports, 10 (1) p. 15322. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_83F91943D332]
Driving Under the Influence of Drugs: A Single Parallel Monitoring-Based Quantification Approach on Whole Blood.
Joye T., Rocher K., Déglon J., Sidibé J., Favrat B., Augsburger M., Thomas A., 2020/08/26. Frontiers in chemistry, 8 p. 626. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E914F0B587CB]
High-Throughput Qualitative and Quantitative Drug Checking by MALDI HRMS.
Joye T., Widmer C., Morger Mégevand R., Longère S., Augsburger M., Thomas A., 2020/08/25. Frontiers in chemistry, 8 p. 695. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1DEDED167AB9]
2017
 
Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling
Marin Bosch B, Bringard A, Logrieco MG, Lauer E, Imobersteg NM, Ferretti G, Thomas A, Schwartz S, Igloi K, 2017/10..
[DOI][serval:BIB_5A16836CADED]
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