Département d'immunobiologie

Equipe principale
Publications | Mémoires et thèses

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2189 publications

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MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.
Baens M., Bonsignore L., Somers R., Vanderheydt C., Weeks S.D., Gunnarsson J., Nilsson E., Roth R.G., Thome M., Marynen P., 2014. PLoS One, 9 (8) pp. e103774.
Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity.
Jaworski M., Marsland B.J., Gehrig J., Held W., Favre S., Luther S.A., Perroud M., Golshayan D., Gaide O., Thome M., 2014. EMBO Journal, 33 (23) pp. 2765-2781.
 
Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function.
Zhang L., Tschumi B.O., Corgnac S., Rüegg M.A., Hall M.N., Mach J.P., Romero P., Donda A., 2014. Journal of Immunology, 193 (4) pp. 1759-1765.
 
MHC Class II Transactivator Is an In Vivo Regulator of Osteoclast Differentiation and Bone Homeostasis Co-opted From Adaptive Immunity.
Benasciutti E., Mariani E., Oliva L., Scolari M., Perilli E., Barras E., Milan E., Orfanelli U., Fazzalari N.L., Campana L. et al., 2014. Journal of Bone and Mineral Research, 29 (2) pp. 290-303.
miR-34a/SIRT6 in squamous differentiation and cancer.
Dotto G.P., Karine L., 2014. Cell cycle, 13 (7) pp. 1055-1056. Peer-reviewed.
 
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
Allam R., Lawlor K.E., Yu E.C., Mildenhall A.L., Moujalled D.M., Lewis R.S., Ke F., Mason K.D., White M.J., Stacey K.J. et al., 2014. EMBO Reports, 15 (9) pp. 982-990.
 
Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.
Brooks Y.S., Ostano P., Jo S.H., Dai J., Getsios S., Dziunycz P., Hofbauer G.F., Cerveny K., Chiorino G., Lefort K. et al., 2014. Journal of Clinical Investigation, 124 (5) pp. 2260-2276.
 
Multifocal epithelial tumors and field cancerization: stroma as a primary determinant.
Dotto G.P., 2014. Journal of Clinical Investigation, 124 (4) pp. 1446-1453.
MyD88 and TLR9 dependent immune responses mediate resistance to Leishmania guyanensis infections, irrespective of Leishmania RNA virus burden.
Ives A., Masina S., Castiglioni P., Prével F., Revaz-Breton M., Hartley M.A., Launois P., Fasel N., Ronet C., 2014. PLoS One, 9 (5) pp. e96766.
NOTCH1 can initiate NF-κB activation via cytosolic interactions with components of the T cell Signalosome.
Shin H.M., Tilahun M.E., Cho O.H., Chandiran K., Kuksin C.A., Keerthivasan S., Fauq A.H., Golde T.E., Miele L., Thome M. et al., 2014. Frontiers in Immunology, 5 p. 249.
Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development.
Coxam B., Sabine A., Bower N.I., Smith K.A., Pichol-Thievend C., Skoczylas R., Astin J.W., Frampton E., Jaquet M., Crosier P.S. et al., 2014. Cell Reports, 7 (3) pp. 623-633.
Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains.
Balam S., Olugbile S., Servis C., Diakité M., D'Alessandro A., Frank G., Moret R., Nebie I., Tanner M., Felger I. et al., 2014. Malaria Journal, 13 p. 510.
Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.
Céspedes N., Habel C., Lopez-Perez M., Castellanos A., Kajava A.V., Servis C., Felger I., Moret R., Arévalo-Herrera M., Corradin G. et al., 2014. PLoS One, 9 (6) pp. e100440.
Prenatal therapy in developmental disorders: drug targeting via intra-amniotic injection to treat X-linked hypohidrotic ectodermal dysplasia
Hermes K., Schneider P., Krieg P., Dang A.T., Huttner K., Schneider H., 2014. Journal of Investigative Dermatology, 134 (12) pp. 2985-2987. Peer-reviewed.
 
Pressing the right buttons: signaling in lymphangiogenesis.
Coso S., Bovay E., Petrova T.V., 2014. Blood, 123 (17) pp. 2614-2624.
Priming of CD8 + T Cell Responses to Liver Stage Malaria Parasite Antigens
Corradin G., Levitskaya J., 2014. Frontiers In Immunology, 5 p. 527. Peer-reviewed.
Protein energy malnutrition increases arginase activity in monocytes and macrophages.
Corware K., Yardley V., Mack C., Schuster S., Al-Hassi H., Herath S., Bergin P., Modolell M., Munder M., Müller I. et al., 2014. Nutrition and Metabolism, 11 (1) p. 51.
PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnt(high) Metastatic Colon Cancer Cells.
Ragusa S., Cheng J., Ivanov K.I., Zangger N., Ceteci F., Bernier-Latmani J., Milatos S., Joseph J.M., Tercier S., Bouzourene H. et al., 2014. Cell Reports, 8 (6) pp. 1957-1973. Peer-reviewed.
 
Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing.
Scott C., Bonner J., Min D., Boughton P., Stokes R., Cha K.M., Walters S.N., Maslowski K., Sierro F., Grey S.T. et al., 2014. American Journal of Physiology. Cell Physiology, 307 (4) pp. C349-C357.
Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood.
Weinkopff T., de Oliveira C.I., de Carvalho A.M., Hauyon-La Torre Y., Muniz A.C., Miranda J.C., Barral A., Tacchini-Cottier F., 2014. PLoS Neglected Tropical Diseases, 8 (1) pp. e2627.
Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.
Zhu Z., Todorova K., Lee K.K., Wang J., Kwon E., Kehayov I., Kim H.G., Kolev V., Dotto G.P., Lee S.W. et al., 2014. Cancer Research, 74 (7) pp. 2082-2093. Peer-reviewed.
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses.
Fasnacht N., Huang H.Y., Koch U., Favre S., Auderset F., Chai Q., Onder L., Kallert S., Pinschewer D.D., MacDonald H.R. et al., 2014. Journal of Experimental Medicine, 211 (11) pp. 2265-2279.
Targeted nasal vaccination provides antibody-independent protection against Staphylococcus aureus.
Misstear K., McNeela E.A., Murphy A.G., Geoghegan J.A., O'Keeffe K.M., Fox J., Chan K., Heuking S., Collin N., Foster T.J. et al., 2014. Journal of Infectious Diseases, 209 (9) pp. 1479-1484. Peer-reviewed.
Targeting B-cell lymphomas with inhibitors of the MALT1 paracaspase.
Hailfinger S., Lenz G., Thome M., 2014. Current Opinion in Chemical Biology, 23C pp. 47-55. Peer-reviewed.
The BAFF/APRIL system in SLE pathogenesis.
Vincent F.B., Morand E.F., Schneider P., Mackay F., 2014. Nature Reviews. Rheumatology, 10 (6) pp. 365-373.
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Hartley M.A., Drexler S., Ronet C., Beverley S.M., Fasel N., 2014. Trends in Parasitology, 30 (8) pp. 412-422.
The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge.
Chen K.W., Groß C.J., Sotomayor F.V., Stacey K.J., Tschopp J., Sweet M.J., Schroder K., 2014. Cell Reports, 8 (2) pp. 570-582.
 
The Oncogene ATF3 Is Potentiated by Cyclosporine A and Ultraviolet Light A.
Dziunycz P.J., Lefort K., Wu X., Freiberger S.N., Neu J., Djerbi N., Iotzowa-Weiss G., French L.E., Dotto G.P., Hofbauer G.F., 2014. Journal of Investigative Dermatology, 134 (7) pp. 1998-2004.
 
The spectrum of opportunistic diseases complicating sarcoidosis.
Jamilloux Y., Valeyre D., Lortholary O., Bernard C., Kerever S., Lelievre L., Neel A., Broussolle C., Seve P., 2014. Autoimmunity Reviews, 14 (1) pp. 64-74.
Therapeutic Blockade of LIGHT Interaction With Herpesvirus Entry Mediator and Lymphotoxin β Receptor Attenuates In Vivo Cytotoxic Allogeneic Responses.
Del Rio M.L., Fernandez-Renedo C., Scheu S., Pfeffer K., Shintani Y., Kronenberg M., Chaloin O., Schneider P., Rodriguez-Barbosa J.I., 2014. Transplantation, 98 (11) pp. 1165-1174. Peer-reviewed.
 
Timing is everything: dendritic cell subsets in murine Leishmania infection.
Ashok D., Acha-Orbea H., 2014. Trends in Parasitology, 30 (10) pp. 499-507.
 
Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members.
Schneider P., Willen L., Smulski C.R., 2014. Methods in Enzymology, 545 pp. 103-125.
 
Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes.
Yang C.Y., Vogt T.K., Favre S., Scarpellino L., Huang H.Y., Tacchini-Cottier F., Luther S.A., 2014. Proceedings of the National Academy of Sciences of the United States of America, 111 (1) pp. E109-E118.
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.
Weber B., Schuster S., Zysset D., Rihs S., Dickgreber N., Schürch C., Riether C., Siegrist M., Schneider C., Pawelski H. et al., 2014. PLoS Pathogens, 10 (1) pp. e1003900.
 
SOX2 expression associates with stem cell state in human ovarian carcinoma.
Bareiss P.M., Paczulla A., Wang H., Schairer R., Wiehr S., Kohlhofer U., Rothfuss O.C., Fischer A., Perner S., Staebler A. et al., 2013/09/01. Cancer research, 73 (17) pp. 5544-5555. Peer-reviewed.
 
Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production.
Kolly L., Busso N., von Scheven-Gete A., Bagnoud N., Moix I., Holzinger D., Simon G., Ives A., Guarda G., So A. et al., 2013/06. The Journal of allergy and clinical immunology, 131 (6) pp. 1635-1643. Peer-reviewed.
GRSF1 regulates RNA processing in mitochondrial RNA granules.
Jourdain A.A., Koppen M., Wydro M., Rodley C.D., Lightowlers R.N., Chrzanowska-Lightowlers Z.M., Martinou J.C., 2013/03/05. Cell metabolism, 17 (3) pp. 399-410. Peer-reviewed.
 
A miR-34a-SIRT6 axis in the squamous cell differentiation network.
Lefort K., Brooks Y., Ostano P., Cario-André M., Calpini V., Guinea-Viniegra J., Albinger-Hegyi A., Hoetzenecker W., Kolfschoten I., Wagner E.F. et al., 2013. EMBO Journal, 32 (16) pp. 2248-2263.
Activin a inhibits antigen-induced allergy in murine epicutaneous sensitization.
Kypriotou M., Rivero D., Haller S., Mariotto A., Huber M., Acha-Orbea H., Werner S., Hohl D., 2013. Frontiers in Immunology, 4 (246) pp. 1-10.
Antigen sparing with adjuvanted inactivated polio vaccine based on Sabin strains.
Westdijk J., Koedam P., Barro M., Steil B.P., Collin N., Vedvick T.S., Bakker W.A., van der Ley P., Kersten G., 2013. Vaccine, 31 (9) pp. 1298-1304. Peer-reviewed.
 
Antigenicity and immunogenicity of a novel chimeric peptide antigen based on the P. vivax circumsporozoite protein.
Céspedes N., Arévalo-Herrera M., Felger I., Reed S., Kajava A.V., Corradin G., Herrera S., 2013. Vaccine, 31 (42) pp. 4923-4930.
Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia.
Abebe T., Takele Y., Weldegebreal T., Cloke T., Closs E., Corset C., Hailu A., Hailu W., Sisay Y., Corware K. et al., 2013. PLoS Neglected Tropical Diseases, 7 (3) pp. e2134.
Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.
Takele Y., Abebe T., Weldegebreal T., Hailu A., Hailu W., Hurissa Z., Ali J., Diro E., Sisay Y., Cloke T. et al., 2013. PLoS Neglected Tropical Diseases, 7 (1) pp. e1977.
 
Cancers du sein chez l'homme: quatre cas avec différenciation neuroendocrine.
Nobile A., Viguet-Carin S., Matter M., Zaman K., Bisig B., Fiche M., 2013. dans 36e Assises de Pathologie.
CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses.
Corgnac S., Perret R., Derré L., Zhang L., Stirnemann K., Zauderer M., Speiser D.E., Mach J.P., Romero P., Donda A., 2013. Cancer Immunology, Immunotherapy, 62 (4) pp. 747-760.
 
Complex roles of inflammasomes in carcinogenesis.
Drexler S.K., Yazdi A.S., 2013. Cancer Journal, 19 (6) pp. 468-472.
 
Crosstalk between neutrophils and dendritic cells: a context-dependent process.
Schuster S., Hurrell B., Tacchini-Cottier F., 2013. Journal of Leukocyte Biology, 94 (4) pp. 671-675.
 
Crystal structure of NLRC4 reveals its autoinhibition mechanism.
Hu Z., Yan C., Liu P., Huang Z., Ma R., Zhang C., Wang R., Zhang Y., Martinon F., Miao D. et al., 2013. Science, 341 (6142) pp. 172-175. Peer-reviewed.
Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly.
Smulski C.R., Beyrath J., Decossas M., Chekkat N., Wolff P., Estieu-Gionnet K., Guichard G., Speiser D., Schneider P., Fournel S., 2013. Journal of Biological Chemistry, 288 (15) pp. 10914-10922.
Detection of Leishmania RNA virus in Leishmania parasites.
Zangger H., Ronet C., Desponds C., Kuhlmann F.M., Robinson J., Hartley M.A., Prevel F., Castiglioni P., Pratlong F., Bastien P. et al., 2013. PLoS Neglected Tropical Diseases, 7 (1) pp. e2006.
 
Did cholera toxin finally get caught?
Martinon F., van der Goot F.G., 2013. Cell Host and Microbe, 13 (5) pp. 501-503.
 
DL4-mediated Notch signaling is required for the development of fetal αβ and γδ T cells.
Ferrero I., Koch U., Claudinot S., Favre S., Radtke F., Luther S.A., MacDonald H.R., 2013. European Journal of Immunology, 43 (11) pp. 2845-2853.
DNA structure-specific priming of ATR activation by DNA-PKcs.
Vidal-Eychenié S., Décaillet C., Basbous J., Constantinou A., 2013. Journal of Cell Biology, 202 (3) pp. 421-429.
 
Dynamin-SNARE interactions control trans-SNARE formation in intracellular membrane fusion.
Alpadi K., Kulkarni A., Namjoshi S., Srinivasan S., Sippel K.H., Ayscough K., Zieger M., Schmidt A., Mayer A., Evangelista M. et al., 2013. Nature Communications, 4 p. 1704.
Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials.
Tappy L., Egli L., Lecoultre V., Schneider P., 2013. Nutrition and Metabolism, 10 (1) p. 54.
 
Engineering, conjugation, and immunogenicity assessment of Escherichia coli O121 O antigen for its potential use as a typhoid vaccine component.
Wetter M., Kowarik M., Steffen M., Carranza P., Corradin G., Wacker M., 2013. Glycoconjugate Journal, 30 (5) pp. 511-522.
 
FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.
Lossaint G., Larroque M., Ribeyre C., Bec N., Larroque C., Décaillet C., Gari K., Constantinou A., 2013. Molecular Cell, 51 (5) pp. 678-690.
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro.
Heuking S., Rothen-Rutishauser B., Raemy D.O., Gehr P., Borchard G., 2013. Journal of Nanobiotechnology, 11 (1) p. 29.
 
Histones trigger sterile inflammation by activating the NLRP3 inflammasome.
Allam R., Darisipudi M.N., Tschopp J., Anders H.J., 2013. European Journal of Immunology, 43 (12) pp. 3336-3342.
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.
Smith W., Tomasec P., Aicheler R., Loewendorf A., Nemčovičová I., Wang E.C., Stanton R.J., Macauley M., Norris P., Willen L. et al., 2013. Cell Host and Microbe, 13 (3) pp. 324-335.
Identification of Genes Affecting Vacuole Membrane Fragmentation in Saccharomyces cerevisiae.
Michaillat L., Mayer A., 2013. PLoS One, 8 (2) pp. e54160.
IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity.
Zaiss M.M., Maslowski K.M., Mosconi I., Guenat N., Marsland B.J., Harris N.L., 2013. PLoS Pathogens, 9 (8) pp. e1003531.
Improving the chance of cure of follicular lymphoma by combining immunotherapy and radioimmunotherapy based on anti-CD20 antibodies?
Buchegger F., Mach J.P., Press O.W., Bischof Delaloye A., Larson S.M., Prior J.O., Ketterer N., 2013. Annals of Oncology, 24 (7) pp. 1948-1949.
 
Inducible gene expression in fetal thymic epithelium: A new BAC transgenic model.
Fiorini E., Ferrero I., Poisson C., Scarpellino L., Luther S.A., Macdonald H.R., 2013. Genesis, 51 (10) pp. 717-724.
Innate and adaptive effects of inflammasomes on T cell responses.
Dostert C., Ludigs K., Guarda G., 2013. Current Opinion in Immunology, 25 (3) pp. 359-365.
Innate receptors for adaptive immunity.
Michallet M.C., Rota G., Maslowski K., Guarda G., 2013. Current Opinion in Microbiology, 16 (3) pp. 296-302.
 
Innate signaling promotes formation of regulatory nitric oxide-producing dendritic cells limiting T-cell expansion in experimental autoimmune myocarditis.
Kania G., Siegert S., Behnke S., Prados-Rosales R., Casadevall A., Lüscher T.F., Luther S.A., Kopf M., Eriksson U., Blyszczuk P., 2013. Circulation, 127 (23) pp. 2285-2294.
 
Interstitial dendritic cell guidance by haptotactic chemokine gradients.
Weber M., Hauschild R., Schwarz J., Moussion C., de Vries I., Legler D.F., Luther S.A., Bollenbach T., Sixt M., 2013. Science, 339 (6117) pp. 328-332.
 
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai H., Wenzel S.S., Hailfinger S., Grau M., Kaergel E., Seitz V., Wollert-Wulf B., Pfeifer M., Wolf A., Frick M. et al., 2013. Blood, 122 (13) pp. 2242-2250.
 
LIGHT/HVEM/LTβR interaction as a target for the modulation of the allogeneic immune response in transplantation.
del Rio M.L., Schneider P., Fernandez-Renedo C., Perez-Simon J.A., Rodriguez-Barbosa J.I., 2013. American Journal of Transplantation, 13 (3) pp. 541-551.
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity.
Chai Q., Onder L., Scandella E., Gil-Cruz C., Perez-Shibayama C., Cupovic J., Danuser R., Sparwasser T., Luther S.A., Thiel V. et al., 2013. Immunity, 38 (5) pp. 1013-1024.
 
MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel S.S., Grau M., Mavis C., Hailfinger S., Wolf A., Madle H., Deeb G., Dörken B., Thome M., Lenz P. et al., 2013. Leukemia, 27 (6) pp. 1381-1390.
Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer.
Goruppi S., Dotto G.P., 2013. Trends in Cell Biology, 23 (12) pp. 593-602. Peer-reviewed.
 
Mitotic figure counts are significantly overestimated in resection specimens of invasive breast carcinomas.
Lehr H.A., Rochat C., Schaper C., Nobile A., Shanouda S., Vijgen S., Gauthier A., Obermann E., Leuba S., Schmidt M. et al., 2013. Modern Pathology, 26 (3) pp. 336-342.
 
Modern Vaccines/Adjuvants Formulation-Session 2 (Plenary II): May 15-17, 2013-Lausanne, Switzerland.
Collin N., 2013. Human Vaccines and Immunotherapeutics, 9 (9) pp. 2015-2016.
 
Molecular typing of mycobacteria isolated from extrapulmonary tuberculosis patients at Debre Birhan Referral Hospital, central Ethiopia.
Garedew L., Mihret A., Abebe T., Ameni G., 2013. Scandinavian Journal of Infectious Diseases, 45 (7) pp. 512-518.
Monoubiquitination and Activity of the Paracaspase MALT1 Requires Glutamate 549 in the Dimerization Interface.
Cabalzar K., Pelzer C., Wolf A., Lenz G., Iwaszkiewicz J., Zoete V., Hailfinger S., Thome M., 2013. PLoS One, 8 (8) pp. e72051.
NLRC5, at the Heart of Antigen Presentation.
Neerincx A., Castro W., Guarda G., Kufer T.A., 2013. Frontiers in Immunology, 4 p. 397. Peer-reviewed.
No Evidence That Soluble TACI Induces Signalling via Membrane-Expressed BAFF and APRIL in Myeloid Cells.
Nys J., Smulski C.R., Tardivel A., Willen L., Kowalczyk C., Donzé O., Huard B., Hess H., Schneider P., 2013. PLoS One, 8 (4) pp. e61350.
 
Notch signaling regulates follicular helper T cell differentiation.
Auderset F., Schuster S., Fasnacht N., Coutaz M., Charmoy M., Koch U., Favre S., Wilson A., Trottein F., Alexander J. et al., 2013. Journal of Immunology, 191 (5) pp. 2344-2350.
Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides.
Pellaton C., Perrin Y., Boudousquié C., Barbier N., Wassenberg J., Corradin G., Thierry A.C., Audran R., Reymond C., Spertini F., 2013. Clinical and Translational Allergy, 3 (1) p. 17.
 
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Yan Y., Jiang W., Spinetti T., Tardivel A., Castillo R., Bourquin C., Guarda G., Tian Z., Tschopp J., Zhou R., 2013. Immunity, 38 (6) pp. 1154-1163.
 
On the Rab again-the PATh to mTORC1 activation.
Gopaldass N., Rompf M., Mayer A., 2013. EMBO Reports, 14 (5) pp. 398-399.
 
Paracaspase
Hailfinger S., Thome M, 2013. pp. 2295-2300 dans Rawlings N.D., Salvesen G.S. (eds.) Handbook of proteolytic enzymes chap. 515, Academic Press.
Pathogenic role of basic calcium phosphate crystals in destructive arthropathies.
Ea H.K., Chobaz V., Nguyen C., Nasi S., van Lent P., Daudon M., Dessombz A., Bazin D., McCarthy G., Jolles-Haeberli B. et al., 2013. Plos One, 8 (2) pp. e57352.
 
Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells.
Ivanov K.I., Agalarov Y., Valmu L., Samuilova O., Liebl J., Houhou N., Maby-El Hajjami H., Norrmén C., Jaquet M., Miura N. et al., 2013. Molecular and Cellular Biology, 33 (19) pp. 3749-3761.
PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.
Thuille N., Wachowicz K., Hermann-Kleiter N., Kaminski S., Fresser F., Lutz-Nicoladoni C., Leitges M., Thome M., Massoumi R., Baier G., 2013. PLoS One, 8 (1) pp. e53709.
 
Progesterone/RANKL is a major regulatory axis in the human breast.
Tanos T., Sflomos G., Echeverria P.C., Ayyanan A., Gutierrez M., Delaloye J.F., Raffoul W., Fiche M., Dougall W., Schneider P. et al., 2013. Science Translational Medicine, 5 (182) pp. 182ra55. Peer-reviewed.
Radioimmunotherapy combined with maintenance anti-CD20 antibody may trigger long-term protective T cell immunity in follicular lymphoma patients.
Buchegger F., Larson S.M., Mach J.P., Chalandon Y., Dietrich P.Y., Cairoli A., Prior J.O., Romero P., Speiser D.E., 2013. Clinical and Developmental Immunology, 2013 p. 875343.
 
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia.
Schmiedel B.J., Scheible C.A., Nuebling T., Kopp H.G., Wirths S., Azuma M., Schneider P., Jung G., Grosse-Hovest L., Salih H.R., 2013. Cancer Research, 73 (2) pp. 683-694.
 
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance.
Schmiedel B.J., Nuebling T., Steinbacher J., Malinovska A., Wende C.M., Azuma M., Schneider P., Grosse-Hovest L., Salih H.R., 2013. Journal of Immunology, 190 (2) pp. 821-831.
Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes.
Jiang W., Wang X., Zeng B., Liu L., Tardivel A., Wei H., Han J., Macdonald H.R., Tschopp J., Tian Z. et al., 2013. Journal of Experimental Medicine, 210 (11) pp. 2465-2476.
 
Red blood cell-derived microparticles isolated from blood units initiate and propagate thrombin generation.
Rubin O., Delobel J., Prudent M., Lion N., Kohl K., Tucker E.I., Tissot J.D., Angelillo-Scherrer A., 2013. Transfusion, 53 (8) pp. 1744-1754.
 
Regulation of innate and adaptive immunity by Notch.
Radtke F., Macdonald H.R., Tacchini-Cottier F., 2013. Nature Reviews. Immunology, 13 (6) pp. 427-437.
 
Regulation of interleukin 1α secretion by inflammasomes.
Yazdi A.S., Drexler S.K., 2013. Annals of the Rheumatic Diseases, 72 Suppl 2 pp. ii96-ii99.
 
Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction.
Duraes F.V., Thelemann C., Sarter K., Acha-Orbea H., Hugues S., Reith W., 2013. Tissue Antigens, 82 (1) pp. 1-15.
 
Role of Toll-Like Receptor 9 Signaling in Experimental Leishmania braziliensis Infection.
Weinkopff T., Mariotto A., Simon G., Hauyon-La Torre Y., Auderset F., Schuster S., Zangger H., Fasel N., Barral A., Tacchini-Cottier F., 2013. Infection and Immunity, 81 (5) pp. 1575-1584.
 
Strain diversity of mycobacteria isolated from pulmonary tuberculosis patients at Debre Birhan Hospital, Ethiopia.
Garedew L., Mihret A., Mamo G., Abebe T., Firdessa R., Bekele Y., Ameni G., 2013. International Journal of Tuberculosis and Lung Disease, 17 (8) pp. 1076-1081.
Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
Pellegrini M., Willen L., Perroud M., Krushinskie D., Strauch K., Cuervo H., Day E.S., Schneider P., Zheng T.S., 2013. FEBS Journal, 280 (8) pp. 1818-1829.
 
Susceptibility of clinical isolates of Leishmania aethiopica to miltefosine, paromomycin, amphotericin B and sodium stibogluconate using amastigote-macrophage in vitro model.
Utaile M., Kassahun A., Abebe T., Hailu A., 2013. Experimental Parasitology, 134 (1) pp. 68-75.
 
Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia.
Ventura R., Brunner L., Heriyanto B., de Boer O., O'Hara M., Huynh C., Suhardono M., Collin N., 2013. Vaccine, 31 (12) pp. 1641-1645.
 
The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
Schweneker K., Gorka O., Schweneker M., Poeck H., Tschopp J., Peschel C., Ruland J., Gross O., 2013. Immunobiology, 218 (4) pp. 664-673.
The Nlrp3 inflammasome regulates acute graft-versus-host disease.
Jankovic D., Ganesan J., Bscheider M., Stickel N., Weber F.C., Guarda G., Follo M., Pfeifer D., Tardivel A., Ludigs K. et al., 2013. Journal of Experimental Medicine, 210 (10) pp. 1899-1910.
The Oncogene Metadherin Modulates the Apoptotic Pathway Based on the Tumor Necrosis Factor Superfamily Member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in Breast Cancer.
Zhang N., Wang X., Huo Q., Li X., Wang H., Schneider P., Hu G., Yang Q., 2013. Journal of Biological Chemistry, 288 (13) pp. 9396-9407.
 
The protease activity of the paracaspase MALT1 is controlled by monoubiquitination.
Pelzer C., Cabalzar K., Wolf A., Gonzalez M., Lenz G., Thome M., 2013. Nature Immunology, 14 (4) pp. 337-345.
The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1.
Dai J., Brooks Y., Lefort K., Getsios S., Dotto G.P., 2013. PLoS One, 8 (7) pp. e70392.
 
The therapeutic potential of immune cross-talk in leishmaniasis.
Hartley M.A., Kohl K., Ronet C., Fasel N., 2013. Clinical Microbiology and Infection, 19 (2) pp. 119-130.
Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4.
Kong M., Muñoz N., Valdivia A., Alvarez A., Herrera-Molina R., Cárdenas A., Schneider P., Burridge K., Quest A.F., Leyton L., 2013. Biochimica et Biophysica Acta. Molecular Cell Research, 1833 (6) pp. 1409-1420. Peer-reviewed.
 
Tumeurs de l'appareil locomoteur: de la simple "bosse" a la prise en charge multidisciplinaire [Tumors of the musculoskeletal system: from the "lumps" to multidisciplinary care].
Cherix S., Varelas N., Letovanec I., Becce F., Gay B., Matter M., Gonzalez M., Saucy F., Christen T., Rüdiger H.A., 2013. Revue Médicale Suisse, 9 (411) pp. 2385-2389. Peer-reviewed.
 
Guidelines for the use and interpretation of assays for monitoring autophagy.
Klionsky D.J., Abdalla F.C., Abeliovich H., Abraham R.T., Acevedo-Arozena A., Adeli K., Agholme L., Agnello M., Agostinis P., Aguirre-Ghiso J.A. et al., 2012/04. Autophagy, 8 (4) pp. 445-544. Peer-reviewed.
 
A novel Th cell epitope of Candida albicans mediates protection from fungal infection.
Bär E., Gladiator A., Bastidas S., Roschitzki B., Acha-Orbea H., Oxenius A., LeibundGut-Landmann S., 2012. Journal of Immunology, 188 (11) pp. 5636-5643.
 
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis.
Dorhoi A., Nouailles G., Jörg S., Hagens K., Heinemann E., Pradl L., Oberbeck-Müller D., Duque-Correa M.A., Reece S.T., Ruland J. et al., 2012. European Journal of Immunology, 42 (2) pp. 374-384.
Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1.
Herrera-Molina R., Frischknecht R., Maldonado H., Seidenbecher C.I., Gundelfinger E.D., Hetz C., Aylwin Mde L, Schneider P., Quest A.F., Leyton L., 2012. PLoS One, 7 (3) pp. e34295.
 
Backseat drivers: the hidden influence of microbial viruses on disease.
Hartley M.A., Ronet C., Fasel N., 2012. Current Opinion in Microbiology, 15 (4) pp. 538-545. Peer-reviewed.
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1.
Kulangara C., Luedin S., Dietz O., Rusch S., Frank G., Mueller D., Moser M., Kajava A.V., Corradin G., Beck H.P. et al., 2012. PLoS One, 7 (10) pp. e46112.
Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1.
Michaillat L., Baars T.L., Mayer A., 2012. Molecular Biology of the Cell, 23 (5) pp. 881-895.
 
Chitosan-based delivery systems for mucosal vaccination
Borchard G., Esmaeili F., Heuking S., 2012. pp. 211-224 dans Sarmento B., Das Neves J. (eds.) Chitosan-based systems for biopharmaceuticals: delivery, targeting and polymer therapeutics chap. 12, Wiley.
CSP-A Model for In Vivo Presentation of Plasmodium berghei Sporozoite Antigens by Hepatocytes.
Balam S., Romero J.F., Bongfen S.E., Guillaume P., Corradin G., 2012. PLoS One, 7 (12) pp. e51875.
 
Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome.
Martinon F., 2012. Immunity, 36 (3) pp. 313-315.
 
Differential peptide binding to CD40 evokes counteractive responses.
Khan S., Alonso L., Roduit C., Bandyopadhyay S., Singh S., Saha S., Tacchini-Cottier F., Roy S., Dietler G., Kasas S. et al., 2012. Human Immunology, 73 (5) pp. 465-469.
Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model.
Tacchini-Cottier F., Weinkopff T., Launois P., 2012. Frontiers in Immunology, 3 p. 32.
Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells.
Chevrier S., Genton C., Malissen B., Malissen M., Acha-Orbea H., 2012. Frontiers in Immunology, 3 p. 27.
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
Voutilainen M., Lindfors P.H., Lefebvre S., Ahtiainen L., Fliniaux I., Rysti E., Murtoniemi M., Schneider P., Schmidt-Ullrich R., Mikkola M.L., 2012. Proceedings of the National Academy of Sciences of the United States of America, 109 (15) pp. 5744-5749. Peer-reviewed.
 
Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants.
Mastelic B., Kamath A.T., Fontannaz P., Tougne C., Rochat A.F., Belnoue E., Combescure C., Auderset F., Lambert P.H., Tacchini-Cottier F. et al., 2012. Journal of Immunology, 189 (12) pp. 5764-5772.
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway.
Menu P., Mayor A., Zhou R., Tardivel A., Ichijo H., Mori K., Tschopp J., 2012. Cell Death and Disease, 3 pp. e261.
 
Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling.
Hafalla J.C., Burgold J., Dorhoi A., Gross O., Ruland J., Kaufmann S.H., Matuschewski K., 2012. Infection and Immunity, 80 (3) pp. 1274-1279.
 
Expression and function of interleukin-7 in secondary and tertiary lymphoid organs.
Huang H.Y., Luther S.A., 2012. Seminars in Immunology, 24 (3) pp. 175-189.
 
Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor.
Bernabeu M., Lopez F.J., Ferrer M., Martin-Jaular L., Razaname A., Corradin G., Maier A.G., Del Portillo H.A., Fernandez-Becerra C., 2012. Cellular Microbiology, 14 (3) pp. 386-400. Peer-reviewed.
 
Heterologous prime-boost regimen adenovector 35-circumsporozoite protein vaccine/recombinant Bacillus Calmette-Guérin expressing the Plasmodium falciparum circumsporozoite induces enhanced long-term memory immunity in BALB/c mice.
Arama C., Assefaw-Redda Y., Rodriguez A., Fernández C., Corradin G., Kaufmann S.H., Reece S.T., Troye-Blomberg M., 2012. Vaccine, 30 (27) pp. 4040-4045.
 
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.
Allam R., Scherbaum C.R., Darisipudi M.N., Mulay S.R., Hägele H., Lichtnekert J., Hagemann J.H., Rupanagudi K.V., Ryu M., Schwarzenberger C. et al., 2012. Journal of the American Society of Nephrology, 23 (8) pp. 1375-1388.
 
Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.
Lefebvre S., Fliniaux I., Schneider P., Mikkola M.L., 2012. Journal of Investigative Dermatology, 132 (4) pp. 1094-1102.
 
Impact of Sirtuin 2 knockout on innate immune responses
Ciarlo E., Lugrin J., dos Santos Pinheiro I., Le Roy D., Moulan N., Yamamoto H., Acha-Orbea H., Calandra T., Auwerx J., Roger T., 2012. p. 271 dans European Congress of Immunology, Immunology.
 
In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption.
Larbouret C., Gaborit N., Chardès T., Coelho M., Campigna E., Bascoul-Mollevi C., Mach J.P., Azria D., Robert B., Pèlegrin A., 2012. Neoplasia, 14 (2) pp. 121-130. Peer-reviewed.
 
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.
Gross O., Yazdi A.S., Thomas C.J., Masin M., Heinz L.X., Guarda G., Quadroni M., Drexler S.K., Tschopp J., 2012. Immunity, 36 (3) pp. 388-400.
 
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes.
Erener S., Pétrilli V., Kassner I., Minotti R., Castillo R., Santoro R., Hassa P.O., Tschopp J., Hottiger M.O., 2012. Molecular Cell, 46 (2) pp. 200-211.
 
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Vince J.E., Wong W.W., Gentle I., Lawlor K.E., Allam R., O'Reilly L., Mason K., Gross O., Ma S., Guarda G. et al., 2012. Immunity, 36 (2) pp. 215-227.
Introduction to monoclonal antibodies.
Mach J.P., 2012. Cancer Immunity, 12 p. 11.
Leishmania RNA virus: when the host pays the toll.
Hartley M.A., Ronet C., Zangger H., Beverley S.M., Fasel N., 2012. Frontiers in Cellular and Infection Microbiology, 2 p. 99.
Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in ethiopia.
Abebe T., Hailu A., Woldeyes M., Mekonen W., Bilcha K., Cloke T., Fry L., Seich Al Basatena N.K., Corware K., Modolell M. et al., 2012. PLoS Neglected Tropical Diseases, 6 (6) pp. e1684.
Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo.
Collin N., Assumpção T.C., Mizurini D.M., Gilmore D.C., Dutra-Oliveira A., Kotsyfakis M., Sá-Nunes A., Teixeira C., Ribeiro J.M., Monteiro R.Q. et al., 2012. Arteriosclerosis, Thrombosis, and Vascular Biology, 32 (9) pp. 2185-2198. Peer-reviewed.
 
Malaria vaccine development using synthetic peptides as a technical platform.
Corradin G., Céspedes N., Verdini A., Kajava A.V., Arévalo-Herrera M., Herrera S., 2012. Advances in Immunology, 114 pp. 107-149.
 
Measuring the inflammasome.
Gross O., 2012. Methods in Molecular Biology, 844 pp. 199-222.
 
Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.
Sabine A., Agalarov Y., Maby-El Hajjami H., Jaquet M., Hägerling R., Pollmann C., Bebber D., Pfenniger A., Miura N., Dormond O. et al., 2012. Developmental Cell, 22 (2) pp. 430-445.
 
Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases.
Macia L., Thorburn A.N., Binge L.C., Marino E., Rogers K.E., Maslowski K.M., Vieira A.T., Kranich J., Mackay C.R., 2012. Immunological Reviews, 245 (1) pp. 164-176.
Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.
Hu B., Castillo E., Harewood L., Ostano P., Reymond A., Dummer R., Raffoul W., Hoetzenecker W., Hofbauer G.F., Dotto G.P., 2012. Cell, 149 (6) pp. 1207-1220. Peer-reviewed.
Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome.
Ferone G., Thomason H.A., Antonini D., De Rosa L., Hu B., Gemei M., Zhou H., Ambrosio R., Rice D.P., Acampora D. et al., 2012. EMBO Molecular Medicine, 4 (3) pp. 192-205.
 
NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells.
Kupz A., Guarda G., Gebhardt T., Sander L.E., Short K.R., Diavatopoulos D.A., Wijburg O.L., Cao H., Waithman J.C., Chen W. et al., 2012. Nature Immunology, 13 (2) pp. 162-169.
 
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells.
Staehli F., Ludigs K., Heinz L.X., Seguín-Estévez Q., Ferrero I., Braun M., Schroder K., Rebsamen M., Tardivel A., Mattmann C. et al., 2012. Journal of Immunology, 188 (8) pp. 3820-3828.
 
NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesothelioma.
Chow M.T., Tschopp J., Möller A., Smyth M.J., 2012. Immunology and Cell Biology, 90 (10) pp. 983-986. Peer-reviewed.
 
NLRP3 Suppresses NK Cell-Mediated Responses to Carcinogen-Induced Tumors and Metastases.
Chow M.T., Sceneay J., Paget C., Wong C.S., Duret H., Tschopp J., Möller A., Smyth M.J., 2012. Cancer Research, 72 (22) pp. 5721-5732.
Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research.
Fuertes Marraco S.A., Grosjean F., Duval A., Rosa M., Lavanchy C., Ashok D., Haller S., Otten L.A., Steiner Q.G., Descombes P. et al., 2012. Frontiers in Immunology, 3 p. 331.
p21 as a transcriptional co-repressor of S-phase and mitotic control genes.
Ferrándiz N., Caraballo J.M., García-Gutierrez L., Devgan V., Rodriguez-Paredes M., Lafita M.C., Bretones G., Quintanilla A., Muñoz-Alonso M.J., Blanco R. et al., 2012. PLoS One, 7 (5) pp. e37759.
 
p63 and FGFR: when development meets proliferation.
Dotto G.P., 2012. EMBO Molecular Medicine, 4 (3) pp. 165-167. Peer-reviewed.
PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling.
Ando K., Kernan J.L., Liu P.H., Sanda T., Logette E., Tschopp J., Look A.T., Wang J., Bouchier-Hayes L., Sidi S., 2012. Molecular Cell, 47 (5) pp. 681-693.
Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes.
Siegert S., Luther S.A., 2012. Frontiers in Immunology, 3 (285) p. 285. Peer-reviewed.
 
Potential of T-regulatory cells to protect xenografts.
Muller Y.D., Ehirchiou D., Golshayan D., Buhler L.H., Seebach J.D., 2012. Current Opinion in Organ Transplantation, 17 (2) pp. 155-161. Peer-reviewed.
Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major.
Auderset F., Schuster S., Coutaz M., Koch U., Desgranges F., Merck E., MacDonald H.R., Radtke F., Tacchini-Cottier F., 2012. PLoS Pathogens, 8 (3) pp. e1002560.
Sequential analysis of trans-SNARE formation in intracellular membrane fusion.
Alpadi K., Kulkarni A., Comte V., Reinhardt M., Schmidt A., Namjoshi S., Mayer A., Peters C., 2012. PLoS Biology, 10 (1) pp. e1001243.
Simultaneous coexpression of memory-related and effector-related genes by individual human CD8 T cells depends on antigen specificity and differentiation.
Gupta B., Iancu E.M., Gannon P.O., Wieckowski S., Baitsch L., Speiser D.E., Rufer N., 2012. Journal of Immunotherapy, 35 (6) pp. 488-501.
 
Targeting endoplasmic reticulum signaling pathways in cancer.
Martinon F., 2012. Acta Oncologica, 51 (7) pp. 822-830.
 
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.
Heinz L.X., Rebsamen M., Rossi D.C., Staehli F., Schroder K., Quadroni M., Gross O., Schneider P., Tschopp J., 2012. Cell Death and Differentiation, 19 (4) pp. 722-731.
 
The design and characterization of receptor-selective APRIL variants.
Kimberley F.C., van der Sloot A.M., Guadagnoli M., Cameron K., Schneider P., Marquart J.A., Versloot M., Serrano L., Medema J.P., 2012. Journal of Biological Chemistry, 287 (44) pp. 37434-37446.
The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.
Martinon F., 2012. Microbes and Infection, 14 (14) pp. 1293-1300.
 
The interrelations of future global bioenergy potentials, food demand, and agricultural technology
Steinberger Julia, Erb Karl-Heinz, Mayer Andreas, Krausmann Fridolin, Lauk Christian, Plutzar Christoph, Haberl Helmut, 2012., Cambridge University Press.
 
The NF-κB signaling protein Bcl10 regulates actin dynamics by controlling AP1 and OCRL-bearing vesicles.
Marion S., Mazzolini J., Herit F., Bourdoncle P., Kambou-Pene N., Hailfinger S., Sachse M., Ruland J., Benmerah A., Echard A. et al., 2012. Developmental Cell, 23 (5) pp. 954-967.
 
The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes.
Perreau M., Welles H.C., Pellaton C., Gjoksi B., Potin L., Martin R., Harari A., Bett A., Casimiro D., Gall J. et al., 2012. Journal of Virology, 86 (11) pp. 6279-6285.
 
The role of Notch in the differentiation of CD4⁺ T helper cells.
Auderset F., Coutaz M., Tacchini-Cottier F., 2012. Current Topics in Microbiology and Immunology, 360 pp. 115-134.
 
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Drexler S.K., Bonsignore L., Masin M., Tardivel A., Jackstadt R., Hermeking H., Schneider P., Gross O., Tschopp J., Yazdi A.S., 2012. Proceedings of the National Academy of Sciences of the United States of America, 109 (45) pp. 18384-18389.
Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.
Ludigs K., Parfenov V., Du Pasquier R.A., Guarda G., 2012. Cellular and Molecular Life Sciences, 69 (20) pp. 3395-3418. Peer-reviewed.
Yeast vacuoles fragment in an asymmetrical two-phase process with distinct protein requirements.
Zieger M., Mayer A., 2012. Molecular Biology of the Cell, 23 (17) pp. 3438-3449. Peer-reviewed.
 
Preface
Tacchini-Cottier Fabienne, van Zandbergen Ger, 2011/09/19. p. 2 dans Neutrophils in Infectious Diseases, Bentham Science Publisher.
Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis.
Mühlethaler-Mottet A, Flahaut M, Bourloud KB, Nardou K, Coulon A, Liberman J, Thome M, Gross N, 2011/03. Cell death & disease. Peer-reviewed.
 
Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies.
Stubbs J., Olugbile S., Saidou B., Simpore J., Corradin G., Lanzavecchia A., 2011/03. Infection and immunity, 79 (3) pp. 1143-1152. Peer-reviewed.
 
A research agenda for malaria eradication: vaccines.
malERA Consultative Group on Vaccines, 2011. Plos Medicine, 8 (1) pp. e1000398.
 
A role for mitochondria in NLRP3 inflammasome activation.
Zhou R., Yazdi A.S., Menu P., Tschopp J., 2011. Nature, 469 (7329) pp. 221-225.
 
Acute gout: The inflammasome.
Guarda G., Yazdi A.S., D'Ombrain M.C., Drexler S.K., 2011. Current Rheumatology Reviews, 7 (2) pp. 132-140.
 
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity.
Flach T.L., Ng G., Hari A., Desrosiers M.D., Zhang P., Ward S.M., Seamone M.E., Vilaysane A., Mucsi A.D., Fong Y. et al., 2011. Nature Medicine, 17 (4) pp. 479-487.
 
Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection.
Uyttenhove C., Marillier R.G., Tacchini-Cottier F., Charmoy M., Caspi R.R., Damsker J.M., Goriely S., Su D., Van Damme J., Struyf S. et al., 2011. Journal of Leukocyte Biology, 89 (6) pp. 1001-1007.
 
An improved synthesis of dansylated α-galactosylceramide and its use as a fluorescent probe for the monitoring of glycolipid uptake by cells.
Cheng J.M., Chee S.H., Knight D.A., Acha-Orbea H., Hermans I.F., Timmer M.S., Stocker B.L., 2011. Carbohydrate Research, 346 (7) pp. 914-926.
 
Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein.
Arévalo-Herrera M., Soto L., Perlaza B.L., Céspedes N., Vera O., Lenis A.M., Bonelo A., Corradin G., Herrera S., 2011. American Journal of Tropical Medicine and Hygiene, 84 (2 Suppl) pp. 35-42.
Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia.
Loisel S., André P.A., Golay J., Buchegger F., Kadouche J., Cérutti M., Bologna L., Kosinski M., Viertl D., Delaloye A.B. et al., 2011. Molecular Cancer, 10 p. 42.
Are protozoan metacaspases potential parasite killers?
Meslin B., Zalila H., Fasel N., Picot S., Bienvenu A.L., 2011. Parasites and Vectors, 4 pp. 26-32.
Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans.
Link A., Hardie D.L., Favre S., Britschgi M.R., Adams D.H., Sixt M., Cyster J.G., Buckley C.D., Luther S.A., 2011. American Journal of Pathology, 178 (4) pp. 1662-1675.
Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome.
Menu P., Pellegrin M., Aubert J.F., Bouzourene K., Tardivel A., Mazzolai L., Tschopp J., 2011. Cell Death and Disease, 2 pp. e137.
ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation.
Henríquez M., Herrera-Molina R., Valdivia A., Alvarez A., Kong M., Muñoz N., Eisner V., Jaimovich E., Schneider P., Quest A.F. et al., 2011. Journal of Cell Science, 124 (Pt 9) pp. 1581-1588.
 
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Harris J., Hartman M., Roche C., Zeng S.G., O'Shea A., Sharp F.A., Lambe E.M., Creagh E.M., Golenbock D.T., Tschopp J. et al., 2011. Journal of Biological Chemistry, 286 (11) pp. 9587-9597.
 
Biological basis of therapeutic lymphangiogenesis.
Norrmén C., Tammela T., Petrova T.V., Alitalo K., 2011. Circulation, 123 (12) pp. 1335-1351.
 
Calcineurin signaling as a negative determinant of keratinocyte cancer stem cell potential and carcinogenesis.
Dotto G.P., 2011. Cancer Research, 71 (6) pp. 2029-2033.
 
Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.
Jevnikar Z., Obermajer N., Doljak B., Turk S., Gobec S., Svajger U., Hailfinger S., Thome M., Kos J., 2011. Journal of Leukocyte Biology, 90 (1) pp. 99-109.
 
Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity.
Sierro S.R., Donda A., Perret R., Guillaume P., Yagita H., Levy F., Romero P., 2011. European Journal of Immunology, 41 (8) pp. 2217-2228.
 
Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome.
Allam R., Darisipudi M.N., Rupanagudi K.V., Lichtnekert J., Tschopp J., Anders H.J., 2011. Journal of Immunology, 186 (5) pp. 2714-2718.
Destruction of lymphoid organ architecture and hepatitis caused by CD4 T cells.
Matter M.S., Hilmenyuk T., Claus C., Marone R., Schürch C., Tinguely M., Terracciano L., Luther S.A., Ochsenbein A.F., 2011. PLoS One, 6 (9) pp. e24772.
 
Development of an Fn14 agonistic antibody as an anti-tumor agent.
Michaelson J.S., Amatucci A., Kelly R., Su L., Garber E., Day E.S., Berquist L., Cho S., Li Y., Parr M. et al., 2011. mAbs, 3 (4) pp. 362-375.
 
Differential expression of NLRP3 among hematopoietic cells.
Guarda G., Zenger M., Yazdi A.S., Schroder K., Ferrero I., Menu P., Tardivel A., Mattmann C., Tschopp J., 2011. Journal of Immunology, 186 (4) pp. 2529-2534.
Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide.
Siegert S., Huang H.Y., Yang C.Y., Scarpellino L., Carrie L., Essex S., Nelson P.J., Heikenwalder M., Acha-Orbea H., Buckley C.D. et al., 2011. PLoS One, 6 (11) pp. e27618.
 
Guiding blind T cells and dendritic cells: A closer look at fibroblastic reticular cells found within lymph node T zones.
Luther S.A., Vogt T.K., Siegert S., 2011. Immunology Letters, 138 (1) pp. 9-11.
 
IKKα takes control of canonical NF-κB activation.
Pelzer C., Thome M., 2011. Nature Immunology, 12 (9) pp. 815-816.
 
IL-10 controls cystatin C synthesis and blood concentration in response to inflammation through regulation of IFN regulatory factor 8 expression.
Xu Y., Schnorrer P., Proietto A., Kowalski G., Febbraio M.A., Acha-Orbea H., Dickins R.A., Villadangos J.A., 2011. Journal of Immunology, 186 (6) pp. 3666-3673.
Increase of [(18)F]FLT tumor uptake in vivo mediated by FdUrd: toward improving cell proliferation positron emission tomography.
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