Ludwig Lausanne Branch

Equipe principale
Publications | Mémoires et thèses

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812 publications

... | 2022 | 2021 | 2020 | ...
2022
 
Clinical relevance of tumour-associated macrophages.
Pittet M.J., Michielin O., Migliorini D., 2022/06. Nature reviews. Clinical oncology, 19 (6) pp. 402-421. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B8D7D43FF169]
Long-term benefit of lurbinectedin as palliative chemotherapy in progressive malignant pleural mesothelioma (MPM): final efficacy and translational data of the SAKK 17/16 study.
Mark M., Rusakiewicz S., Früh M., Hayoz S., Grosso F., Pless M., Zucali P., Ceresoli G.L., Maconi A., Schneider M. et al., 2022/06. ESMO open, 7 (3) p. 100446. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FA0FF9C4B3E9]
Deciphering the landscape of phosphorylated HLA-II ligands.
Solleder M., Racle J., Guillaume P., Coukos G., Bassani-Sternberg M., Gfeller D., 2022/05/20. iScience, 25 (5) p. 104215. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_54BD67DD87D2]
Proton Pump Inhibitor Use and Efficacy of Nivolumab and Ipilimumab in Advanced Melanoma.
Homicsko K., Dummer R., Hoeller C., Wolchok J.D., Hodi F.S., Larkin J., Ascierto P.A., Atkinson V., Robert C., Postow M.A. et al., 2022/05/05. Cancers, 14 (9) p. 2300. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4D579FC357B1]
Alterations in homologous recombination repair genes in prostate cancer brain metastases.
Rodriguez-Calero A., Gallon J., Akhoundova D., Maletti S., Ferguson A., Cyrta J., Amstutz U., Garofoli A., Paradiso V., Tomlins S.A. et al., 2022/05/03. Nature communications, 13 (1) p. 2400. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_067B8F2489FA]
 
The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis.
Prat-Luri B., Neal C., Passelli K., Ganga E., Amore J., Firmino-Cruz L., Petrova T.V., Müller A.J., Tacchini-Cottier F., 2022/05/03. Cell reports, 39 (5) p. 110777. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_793AA043940A]
The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function.
Wenes M., Jaccard A., Wyss T., Maldonado-Pérez N., Teoh S.T., Lepez A., Renaud F., Franco F., Waridel P., Yacoub Maroun C. et al., 2022/05/03. Cell metabolism, 34 (5) pp. 731-746.e9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17EB92736564]
 
Trabectedin and Durvalumab Combination Is Feasible and Active in Relapsing Ovarian Cancer.
Digklia A., Coukos G., Homicsko K., 2022/05/02. Clinical cancer research, 28 (9) pp. 1745-1747. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0CAC463D4200]
Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth.
Bernier-Latmani J., Cisarovsky C., Mahfoud S., Ragusa S., Dupanloup I., Barras D., Renevey F., Nassiri S., Anderle P., Squadrito M.L. et al., 2022/05. Nature cardiovascular research, 1 (5) pp. 476-490. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_998EFE1BCFC2]
Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
Arnaud M., Chiffelle J., Genolet R., Navarro Rodrigo B., Perez MAS, Huber F., Magnin M., Nguyen-Ngoc T., Guillaume P., Baumgaertner P. et al., 2022/05. Nature biotechnology, 40 (5) pp. 656-660. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_18BFBDDF727B]
 
The current clinical landscape of personalized cancer vaccines.
Fritah H., Rovelli R., Chiang C.L., Kandalaft L.E., 2022/05. Cancer treatment reviews, 106 p. 102383. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1B87E8078A63]
scGate: marker-based purification of cell types from heterogeneous single-cell RNA-seq datasets.
Andreatta M., Berenstein A.J., Carmona S.J., 2022/04/28. Bioinformatics, 38 (9) pp. 2642-2644. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_241F222A7909]
Loss of vascular endothelial notch signaling promotes spontaneous formation of tertiary lymphoid structures.
Fleig S., Kapanadze T., Bernier-Latmani J., Lill J.K., Wyss T., Gamrekelashvili J., Kijas D., Liu B., Hüsing A.M., Bovay E. et al., 2022/04/19. Nature communications, 13 (1) p. 2022. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_513AD0411BD1]
 
Sphingolipids control dermal fibroblast heterogeneity.
Capolupo L., Khven I., Lederer A.R., Mazzeo L., Glousker G., Ho S., Russo F., Montoya J.P., Bhandari D.R., Bowman A.P. et al., 2022/04/15. Science, 376 (6590) pp. eabh1623. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D703E8F69887]
A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
Omer B., Cardenas M.G., Pfeiffer T., Daum R., Huynh M., Sharma S., Nouraee N., Xie C., Tat C., Perconti S. et al., 2022/04/01. Cancer immunology research, 10 (4) pp. 512-524. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_78535A53B294]
 
A new workflow combining magnetic cell separation and impedance-based cell dispensing for gentle, simple and reliable cloning of specific CD8+ T cells.
Ben Khelil M., Aeberli L., Perchaud M., Genolet R., Abdeljaoued S., Borg C., Binda D., Harari A., Jandus C., Muller G. et al., 2022/04. SLAS technology, 27 (2) pp. 130-134. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_97892CDB341E]
Metabolic dynamics instruct CD8<sup>+</sup> T-cell differentiation and functions.
Bevilacqua A., Li Z., Ho P.C., 2022/04. European journal of immunology, 52 (4) pp. 541-549. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B5AE6597A0A]
Radiotherapy plus immune checkpoint blockade in PD(L)-1-resistant metastatic NSCLC.
Ochoa-de-Olza M., Bourhis J., Coukos G., Herrera F.G., 2022/04. The Lancet. Oncology, 23 (4) pp. e157. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BC56553604E1]
Stem-cell-like T cells have a specific entry gate to the tumor.
Held W., Luther S.A., Petrova T.V., 2022/03/14. Cancer cell, 40 (3) pp. 243-245. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_51451730613C]
 
Lighting up the tumor fire with low-dose irradiation.
Herrera F.G., Romero P., Coukos G., 2022/03. Trends in immunology, 43 (3) pp. 173-179. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_49751A0F49EB]
Metabolic programming in dendritic cells tailors immune responses and homeostasis.
Møller S.H., Wang L., Ho P.C., 2022/03. Cellular & molecular immunology, 19 (3) pp. 370-383. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_28FD58401C9C]
 
Metabolic programs tailor T cell immunity in viral infection, cancer, and aging.
Møller S.H., Hsueh P.C., Yu Y.R., Zhang L., Ho P.C., 2022/03/01. Cell metabolism, 34 (3) pp. 378-395. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3C4C3CF20FD3]
 
Navigating Critical Challenges Associated with Immunopeptidomics-Based Detection of Proteasomal Spliced Peptide Candidates.
Lichti C.F., Vigneron N., Clauser K.R., Van den Eynde B.J., Bassani-Sternberg M., 2022/03/01. Cancer immunology research, 10 (3) pp. 275-284. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_81D3B5D58DAB]
 
PERK is a critical metabolic hub for immunosuppressive function in macrophages.
Raines L.N., Zhao H., Wang Y., Chen H.Y., Gallart-Ayala H., Hsueh P.C., Cao W., Koh Y., Alamonte-Loya A., Liu P.S. et al., 2022/03. Nature immunology, 23 (3) pp. 431-445. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8642BC35A947]
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Pataskar A., Champagne J., Nagel R., Kenski J., Laos M., Michaux J., Pak H.S., Bleijerveld O.B., Mordente K., Navarro J.M. et al., 2022/03. Nature, 603 (7902) pp. 721-727. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED604B40AD79]
Safety and Efficacy of Ipilimumab plus Nivolumab and Sequential Selective Internal Radiation Therapy in Hepatic and Extrahepatic Metastatic Uveal Melanoma.
Aedo-Lopez V., Gérard C.L., Boughdad S., Gautron Moura B., Berthod G., Digklia A., Homicsko K., Schaefer N., Duran R., Cuendet M.A. et al., 2022/02/24. Cancers, 14 (5) p. 1162. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8F8308EFA619]
 
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function
Lötscher J., Martí I Líndez A.A., Kirchhammer N., Cribioli E., Giordano Attianese GMP, Trefny M.P., Lenz M., Rothschild S.I., Strati P., Künzli M. et al., 2022/02/17. Cell, 185 (4) pp. 585-602.e29. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88810074314B]
PARP inhibition in ovarian cancer: what is still missing?
Morotti M., Ghisoni E., 2022/02/15. European Journal of Gynaecological Oncology, 43 (1) pp. 143-145.
[URN][WoS][serval:BIB_66073FABE67C]
High levels of monocytic myeloid-derived suppressor cells are associated with favorable outcome in patients with pneumonia and sepsis with multi-organ failure.
Schrijver I.T., Karakike E., Théroude C., Baumgartner P., Harari A., Giamarellos-Bourboulis E.J., Calandra T., Roger T., 2022/02/11. Intensive care medicine experimental, 10 (1) p. 5. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_79AC142AD176]
Improved Multimodal Tumor Necrosis Imaging with IRDye800CW-DOTA Conjugated to an Albumin-Binding Domain.
Stroet MCM, de Blois E., de Jong M., Seimbille Y., Mezzanotte L., Löwik CWGM, Panth K.M., 2022/02/09. Cancers, 14 (4) p. 861. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4C46C34DC0F6]
 
Identification of tumor antigens with immunopeptidomics.
Chong C., Coukos G., Bassani-Sternberg M., 2022/02. Nature biotechnology, 40 (2) pp. 175-188. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0938B9EC9DC3]
 
Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.
Friess M.C., Kritikos I., Schineis P., Medina-Sanchez J.D., Gkountidi A.O., Vallone A., Sigmund E.C., Schwitter C., Vranova M., Matti C. et al., 2022/02/01. Cell reports, 38 (5) p. 110334. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A2343778C0A7]
 
Polymer Nanoparticle-Mediated Delivery of Oxidized Tumor Lysate-Based Cancer Vaccines.
Berti C., Graciotti M., Boarino A., Yakkala C., Kandalaft L.E., Klok H.A., 2022/02. Macromolecular bioscience, 22 (2) pp. e2100356. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_561527E3BDD3]
 
High-Throughput Single-Cell TCR-pMHC Dissociation Rate Measurements Performed by an Autonomous Microfluidic Cellular Processing Unit.
Jammes F., Schmidt J., Coukos G., Maerkl S.J., 2022/01/28. ACS sensors, 7 (1) pp. 159-165. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3E11871D7007]
Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes.
Rodriguez-Rivas J., Croce G., Muscat M., Weigt M., 2022/01/25. Proceedings of the National Academy of Sciences of the United States of America, 119 (4) pp. e2113118119. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_905A8698EB11]
A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors.
Fierle J.K., Abram-Saliba J., Atsaves V., Brioschi M., de Tiani M., Reichenbach P., Irving M., Coukos G., Dunn S.M., 2022/01/21. Scientific reports, 12 (1) p. 1136. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7D41964E1822]
The SwissSimilarity 2021 Web Tool: Novel Chemical Libraries and Additional Methods for an Enhanced Ligand-Based Virtual Screening Experience.
Bragina M.E., Daina A., Perez MAS, Michielin O., Zoete V., 2022/01/12. International journal of molecular sciences, 23 (2) p. 811. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9174E37AD078]
 
A roadmap for driving CAR T cells toward the oncogenic immunopeptidome.
Irving M., Zoete V., Bassani-Sternberg M., Coukos G., 2022/01/10. Cancer cell, 40 (1) pp. 20-22. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FF0839215AF4]
SPICA: Swiss portal for immune cell analysis.
Andreatta M., David FPA, Iseli C., Guex N., Carmona S.J., 2022/01/07. Nucleic acids research, 50 (D1) pp. D1109-D1114. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1425D341196A]
SwissBioisostere 2021: updated structural, bioactivity and physicochemical data delivered by a reshaped web interface.
Alessandro C., Antoine D., Marta A S P., Olivier M., Vincent Z., 2022/01/07. Nucleic acids research, 50 (D1) pp. D1382-D1390. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B45F1019EA9E]
Static Adhesion Assay for Human Peripheral Blood Mononuclear Cells.
Vanoni G., Jandus C., Trabanelli S., 2022/01/05. Bio-protocol, 12 (1) pp. e4276. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_09261D64C41B]
 
Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma.
Mohsen M.O., Speiser D.E., Michaux J., Pak H., Stevenson B.J., Vogel M., Inchakalody V.P., de Brot S., Dermime S., Coukos G. et al., 2022/01. Journal for immunotherapy of cancer, 10 (1) pp. e002927. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C41D094CADC7]
 
CAR T cells targeting the ganglioside NGcGM3 control ovarian tumors in the absence of toxicity against healthy tissues.
Cribioli E., Giordano Attianese GMP, Coukos G., Irving M., 2022. Frontiers in immunology, 13 p. 951143. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3BEC9380646B]
Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies.
Wild S.A., Cannell I.G., Nicholls A., Kania K., Bressan D., CRUK IMAXT Grand Challenge Team, Hannon G.J., Sawicka K., 2022. eLife, 11 pp. e80981. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_A9C8C5466322]
Development of a salivary autoantibody biomarker panel for diagnosis of oral cavity squamous cell carcinoma.
Hsueh P.C., Chang K.P., Liu H.P., Chiang W.F., Chan X.Y., Hung C.M., Chu L.J., Wu C.C., 2022. Frontiers in oncology, 12 p. 968570. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_65315BA37C76]
Development of Human ILCs and Impact of Unconventional Cytotoxic Subsets in the Pathophysiology of Inflammatory Diseases and Cancer.
Calvi M., Di Vito C., Frigo A., Trabanelli S., Jandus C., Mavilio D., 2022. Frontiers in immunology, 13 p. 914266. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E16F911609C3]
Editorial: Immunopeptidomic Approaches for the Identification of Tumor (neo)Antigens.
Lill J.R., Bassani-Sternberg M., 2022. Frontiers in immunology, 13 p. 923776. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8DA1622055E1]
Efficacy of Eribulin in Soft Tissue Sarcomas.
Phillips E., Jones R.L., Huang P., Digklia A., 2022. Frontiers in pharmacology, 13 p. 869754. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BAD5D07E845B]
 
Enforcing GLUT3 expression in CD8+ T cells improves fitness and tumor control by promoting glucose uptake and energy storage
Cribioli E., Giordano Attianese GMP, Ginefra P., Signorino-Gelo A., Vuillefroy de Silly R., Vannini N., Hess C., Irving M., Coukos G., 2022. Frontiers in immunology, 13 p. 976628. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3101020C948F]
 
Hallmarks of Cancer: New Dimensions.
Hanahan D., 2022/01. Cancer discovery, 12 (1) pp. 31-46. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EFF5CF54772B]
In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B., Reverte M., Ronet C., Prevel F., Morgenthaler F.D., Desponds C., Lye L.F., Owens K.L., Scarpellino L., Dubey L.K. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941860. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2B104E1E8C7E]
Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.
Herrera F.G., Ronet C., Ochoa de Olza M., Barras D., Crespo I., Andreatta M., Corria-Osorio J., Spill A., Benedetti F., Genolet R. et al., 2022/01. Cancer discovery, 12 (1) pp. 108-133. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D82928F3BB2B]
 
Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells.
Pfirschke C., Zilionis R., Engblom C., Messemaker M., Zou A.E., Rickelt S., Gort-Freitas N.A., Lin Y., Bill R., Siwicki M. et al., 2022/01. Cancer immunology research, 10 (1) pp. 40-55. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6C392024C141]
 
Overcoming Immune Resistance With Radiation Therapy in Prostate Cancer.
Mulvey A., Muggeo-Bertin E., Berthold D.R., Herrera F.G., 2022. Frontiers in immunology, 13 p. 859785. Peer-reviewed.
[DOI][Pmid][serval:BIB_DE34735C811E]
 
Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes.
Tratwal J., Falgayrac G., During A., Bertheaume N., Bataclan C., Tavakol D.N., Campos V., Duponchel L., Daley G.Q., Penel G. et al., 2022. Frontiers in endocrinology, 13 p. 1001210. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7D71BFC9E521]
Randomized double-blind clinical study in patients with COVID-19 to evaluate the safety and efficacy of a phytomedicine (P2Et).
Urueña C., Ballesteros-Ramírez R., Gomez-Cadena A., Barreto A., Prieto K., Quijano S., Aschner P., Martínez C., Zapata-Cardona M.I., El-Ahanidi H. et al., 2022. Frontiers in medicine, 9 p. 991873. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6A18DF559D6B]
Rapid Generation of TCR and CD8αβ Transgenic Virus Specific T Cells for Immunotherapy of Leukemia.
Bajwa G., Arber C., 2022. Frontiers in immunology, 13 p. 830021. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0C6CE3A6605F]
 
Structural Prediction of Peptide–MHC Binding Modes
Perez Marta A. S., Cuendet Michel A., Röhrig Ute F., Michielin Olivier, Zoete Vincent, 2022. pp. 245-282 dans Computational Peptide Science, Springer US.
[DOI][Pmid][serval:BIB_5B61FB9FCC6D]
TEM1-targeting PEGylated PLGA shikonin nanoformulation for immunomodulation and eradication of ovarian cancer.
Matthaiou E.I., Guo Y., Barar J., Sandaltzopoulos R., Kandalaft L.E., Li C., Coukos G., Omidi Y., 2022. BioImpacts, 12 (1) pp. 65-86. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7205BBE80A2D]
TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells
Hope H.C., Pickersgill G., Ginefra P., Vannini N., Cook G.P., Salmond R.J., 2022. Frontiers in immunology, 13 p. 913184. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1D68C4F5AEAF]
 
The Era of Cytotoxic CD4 T Cells.
Cenerenti M., Saillard M., Romero P., Jandus C., 2022. Frontiers in immunology, 13 p. 867189. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5284EC872B4E]
2021
Structure and Plasticity of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Röhrig U.F., Michielin O., Zoete V., 2021/12/23. Journal of medicinal chemistry, 64 (24) pp. 17690-17705. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_27218E957A69]
Ionic Regulation of T-Cell Function and Anti-Tumour Immunity.
Ginefra P., Carrasco Hope H., Spagna M., Zecchillo A., Vannini N., 2021/12/20. International journal of molecular sciences, 22 (24) p. 13668. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BCD9B8C1A1C9]
 
Reduction-Sensitive Protein Nanogels Enhance Uptake of Model and Tumor Lysate Antigens In Vitro by Mouse- and Human-Derived Dendritic Cells.
Berti C., Boarino A., Graciotti M., Bader LPE, Kandalaft L.E., Klok H.A., 2021/12/20. ACS applied bio materials, 4 (12) pp. 8291-8300. Peer-reviewed.
[DOI][Pmid][serval:BIB_0D82E169FC14]
 
Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2.
Antonarakis S.E., Holoubek A., Rapti M., Rademaker J., Meylan J., Iwaszkiewicz J., Zoete V., Wilson C., Taylor J., Ansar M. et al., 2021/12/17. Human molecular genetics, 31 (1) pp. 1-9. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67FE6F734917]
 
Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation.
Duraiswamy J., Turrini R., Minasyan A., Barras D., Crespo I., Grimm A.J., Casado J., Genolet R., Benedetti F., Wicky A. et al., 2021/12/13. Cancer cell, 39 (12) pp. 1623-1642.e20. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4A546D8AF05A]
 
Challenges and opportunities in 2021.
Akkari L., Finley S.D., Ho P.C., Jenkins M., Maier B.B., McGranahan N., Mutebi M., Perera R.M., Robles-Espinoza C.D., Vardhana S. et al., 2021/12. Nature cancer, 2 (12) pp. 1278-1283. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88181154656E]
 
Fueling T-cell Antitumor Immunity: Amino Acid Metabolism Revisited.
Han C., Ge M., Ho P.C., Zhang L., 2021/12. Cancer immunology research, 9 (12) pp. 1373-1382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A31A9CC09CD4]
Infirmière clinicienne de centre du cancer : l’expérience du Centre de la prostate du CHUV [Cancer center clinical nurse: The experience of the CHUV Prostate Cancer Center]
Codeluppi C., Ninane F., Jolliet L., Glemarec P., Orcurto A., Rakauskas A., Tawadros T., Bosshard P., Eicher M., Herrera F. et al., 2021/12/01. Revue medicale suisse, 17 (761) pp. 2082-2085. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B3EF72B4777A]
 
Turning tumors from cold to inflamed to improve immunotherapy response.
Gerard C.L., Delyon J., Wicky A., Homicsko K., Cuendet M.A., Michielin O., 2021/12. Cancer treatment reviews, 101 p. 102227. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4AB33FCA1873]
Copper-64-Labeled 1C1m-Fc, a New Tool for TEM-1 PET Imaging and Prediction of Lutetium-177-Labeled 1C1m-Fc Therapy Efficacy and Safety.
Delage J.A., Gnesin S., Prior J.O., Barbet J., Le Saëc P., Marionneau-Lambot S., Gouard S., Chérel M., Bourgeois M., Schaefer N. et al., 2021/11/25. Cancers, 13 (23) p. 5936. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1AE49D79BF32]
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Heino S., Fang S., Lähde M., Högström J., Nassiri S., Campbell A., Flanagan D., Raven A., Hodder M., Nasreddin N. et al., 2021/11/19. Science advances, 7 (47) pp. eabj0512. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4CC88CEB1BCE]
Vaccines as Priming Tools for T Cell Therapy for Epithelial Cancers.
Kandalaft L.E., Harari A., 2021/11/19. Cancers, 13 (22) p. 5819. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6B925EAAEE85]
A Personalized Neoantigen Vaccine in Combination with Platinum-Based Chemotherapy Induces a T-Cell Response Coinciding with a Complete Response in Endometrial Carcinoma.
Harari A., Sarivalasis A., de Jonge K., Thierry A.C., Huber F., Boudousquie C., Rossier L., Orcurto A., Imbimbo M., Baumgaertner P. et al., 2021/11/18. Cancers, 13 (22) p. 5801. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7A292F2251A7]
Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium.
Sáinz-Jaspeado M., Smith R.O., Plunde O., Pawelzik S.C., Jin Y., Nordling S., Ding Y., Aspenström P., Hedlund M., Bastianello G. et al., 2021/11/16. Circulation, 144 (20) pp. 1629-1645. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_12F7FC5B8E4A]
Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.
Ho W.W., Gomes-Santos I.L., Aoki S., Datta M., Kawaguchi K., Talele N.P., Roberge S., Ren J., Liu H., Chen I.X. et al., 2021/11/09. Proceedings of the National Academy of Sciences of the United States of America, 118 (45) pp. e2105323118. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E44392371B42]
Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope.
Ebrahimi-Nik H., Moussa M., Englander R.P., Singhaviranon S., Michaux J., Pak H., Miyadera H., Corwin W.L., Keller GLJ, Hagymasi A.T. et al., 2021/11/05. Nature communications, 12 (1) p. 6423. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_63F82E17F0C1]
Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells.
Kalousková B., Skořepa O., Cmunt D., Abreu C., Krejčová K., Bláha J., Sieglová I., Král V., Fábry M., Pola R. et al., 2021/11/02. Biomedicines, 9 (11) p. 1597. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F1D718EDAA50]
Cryogel-based Injectable 3D Microcarrier Co-culture for Support of Hematopoietic Progenitor Niches.
Tavakol D.N., Bonini F., Tratwal J., Genta M., Brefie-Guth J., Braschler T., Naveiras O., 2021/11. Current protocols, 1 (11) pp. e275. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_3CE5A09E5F62]
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G., Tsai C.H., Gallart-Ayala H., Yu Y.R., Franco F., Zaffalon L., Xie X., Li X., Xiao Z., Raines L.N. et al., 2021/11. Nature immunology, 22 (11) pp. 1403-1415. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_38FF542D6B24]
 
An Injectable Meta-Biomaterial: From Design and Simulation to In Vivo Shaping and Tissue Induction.
Béduer A., Bonini F., Verheyen C.A., Genta M., Martins M., Brefie-Guth J., Tratwal J., Filippova A., Burch P., Naveiras O. et al., 2021/10. Advanced materials, 33 (41) pp. e2102350. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5414A74D8E0A]
 
An integrated pipeline for comprehensive analysis of immune cells in human brain tumor clinical samples.
Maas R.R., Soukup K., Klemm F., Kornete M., Bowman R.L., Bedel R., Marie D.N., Álvarez-Prado Á.F., Labes D., Wilson A. et al., 2021/10. Nature protocols, 16 (10) pp. 4692-4721. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_56ABDAED12F3]
 
Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression.
Saghafinia S., Homicsko K., Di Domenico A., Wullschleger S., Perren A., Marinoni I., Ciriello G., Michael I.P., Hanahan D., 2021/10. Cancer discovery, 11 (10) pp. 2638-2657. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E3BABADE6621]
Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells.
Irving M., Lanitis E., Migliorini D., Ivics Z., Guedan S., 2021/10. Human gene therapy, 32 (19-20) pp. 1044-1058. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_24515EABFB7F]
 
Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis.
Klemm F., Möckl A., Salamero-Boix A., Alekseeva T., Schäffer A., Schulz M., Niesel K., Maas R.R., Groth M., Elie B.T. et al., 2021/10. Nature cancer, 2 (10) pp. 1086-1101. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E98C80E092F1]
 
FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma.
Cleary J.M., Raghavan S., Wu Q., Li Y.Y., Spurr L.F., Gupta H.V., Rubinson D.A., Fetter I.J., Hornick J.L., Nowak J.A. et al., 2021/10. Cancer discovery, 11 (10) pp. 2488-2505. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_794632510938]
 
Glutamine gluttony of efferocytes.
Jaccard A., Li X., Ho P.C., 2021/10. Nature metabolism, 3 (10) pp. 1280-1281. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0E25E488861C]
 
Versatile neutrophil functions in cancer.
Siwicki M., Pittet M.J., 2021/10. Seminars in immunology, 57 p. 101538. Peer-reviewed.
[DOI][Pmid][serval:BIB_F7012190BAC7]
A promising platform for predicting toxicity.
Ochoa de Olza M., 2021/09/24. eLife, 10 pp. e73191. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3B55CEFF0A5A]
A Locally Advanced Endometrioid Adenocarcinoma Arising from Vaginal Endometriosis: Management and Review of the Literature
Costanza M., Herrera F.G., Hastir D., Mathevet P., Sarivalasis A., 2021/09/17. Reports, 4 (3) p. 29. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_47314A3E8C85]
 
Specific Protein-Membrane Interactions Promote Packaging of Metallo-β-Lactamases into Outer Membrane Vesicles.
López C., Prunotto A., Bahr G., Bonomo R.A., González L.J., Dal Peraro M., Vila A.J., 2021/09/17. Antimicrobial agents and chemotherapy, 65 (10) pp. e0050721. Peer-reviewed.
[DOI][Pmid][serval:BIB_44A995F8E20C]
Integrating Cancer Vaccines in the Standard-of-Care of Ovarian Cancer: Translating Preclinical Models to Human.
Chiang C.L., Rovelli R., Sarivalasis A., Kandalaft L.E., 2021/09/10. Cancers, 13 (18) p. 4553. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0968A9F9CD4C]
Microfluidic Device for Droplet Pairing by Combining Droplet Railing and Floating Trap Arrays.
Duchamp M., Arnaud M., Bobisse S., Coukos G., Harari A., Renaud P., 2021/09/06. Micromachines, 12 (9) p. 1076. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_550F1A17928D]
A new method to visualize and to spare the ureters during SBRT for oligo metastatic patients.
Muggeo-Bertin E., Moeckli R., Vallet V., Berthold D., Godin S., Bourhis J., Herrera F.G., 2021/09. Technical innovations & patient support in radiation oncology, 19 pp. 7-10. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_5205796889DB]
 
The role of fluorescent and hybrid tracers in radioguided surgery in urogenital malignancies.
DE Vries H.M., Schottelius M., Brouwer O.R., Buckle T., 2021/09. The quarterly journal of nuclear medicine and molecular imaging, 65 (3) pp. 261-270. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5F5C6091280A]
 
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.
Di Pilato M., Kfuri-Rubens R., Pruessmann J.N., Ozga A.J., Messemaker M., Cadilha B.L., Sivakumar R., Cianciaruso C., Warner R.D., Marangoni F. et al., 2021/08/19. Cell, 184 (17) pp. 4512-4530.e22. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7D2B6681B840]
Soluble trivalent engagers redirect cytolytic T cell activity toward tumor endothelial marker 1.
Fierle J.K., Brioschi M., de Tiani M., Wetterwald L., Atsaves V., Abram-Saliba J., Petrova T.V., Coukos G., Dunn S.M., 2021/08/17. Cell reports. Medicine, 2 (8) p. 100362. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3930B2D62A38]
Imaging angiogenesis in atherosclerosis in large arteries with 68Ga-NODAGA-RGD PET/CT: relationship with clinical atherosclerotic cardiovascular disease.
Dietz M., Kamani C.H., Deshayes E., Dunet V., Mitsakis P., Coukos G., Nicod Lalonde M., Schaefer N., Prior J.O., 2021/08/14. EJNMMI research, 11 (1) p. 71. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BC418C20751B]
c-Met enforces proinflammatory and migratory features of human activated CD4<sup>+</sup> T cells.
Benkhoucha M., Tran N.L., Breville G., Senoner I., Jandus C., Lalive P., 2021/08. Cellular & molecular immunology, 18 (8) pp. 2051-2053. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D795C95B3C76]
DCision-making in tumors governs T cell anti-tumor immunity.
Alfei F., Ho P.C., Lo W.L., 2021/08. Oncogene, 40 (34) pp. 5253-5261. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A205E6D27239]
Ovarian cancer with high-level focal ERBB2 amplification responds to trastuzumab and pertuzumab.
Thouvenin L., Charrier M., Clement S., Christinat Y., Tille J.C., Frigeri M., Homicsko K., Michielin O., Bodmer A., Chappuis P.O. et al., 2021/08. Gynecologic oncology reports, 37 p. 100787. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AB2F51C1A9EA]
 
VEGFR-2 redirected CAR-T cells are functionally impaired by soluble VEGF-A competition for receptor binding.
Lanitis E., Kosti P., Ronet C., Cribioli E., Rota G., Spill A., Reichenbach P., Zoete V., Dangaj Laniti D., Coukos G. et al., 2021/08. Journal for immunotherapy of cancer, 9 (8) pp. e002151. Peer-reviewed.
[DOI][Pmid][serval:BIB_3B098C62EF15]
Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING.
Bruand M., Barras D., Mina M., Ghisoni E., Morotti M., Lanitis E., Fahr N., Desbuisson M., Grimm A., Zhang H. et al., 2021/07/20. Cell reports, 36 (3) p. 109412. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_745449157CA6]
 
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8<sup>+</sup> T cells in tumors.
Xu S., Chaudhary O., Rodríguez-Morales P., Sun X., Chen D., Zappasodi R., Xu Z., Pinto AFM, Williams A., Schulze I. et al., 2021/07/13. Immunity, 54 (7) pp. 1561-1577.e7. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7490E53D6718]
Active surveillance in males with low- to intermediate-risk localized prostate cancer: A modern prospective cohort study.
Rakauskas A., Tawadros T., Lucca I., Herrera F., Bourhis J., Burruni R., Gomes M.N., Codeluppi C., Jolliet L., La Rosa S. et al., 2021/07. Investigative and clinical urology, 62 (4) pp. 416-422. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_11DA8B398364]
 
Clonal fitness inferred from time-series modelling of single-cell cancer genomes.
Salehi S., Kabeer F., Ceglia N., Andronescu M., Williams M.J., Campbell K.R., Masud T., Wang B., Biele J., Brimhall J. et al., 2021/07. Nature, 595 (7868) pp. 585-590. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C1DD3A50D86F]
Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity.
Dumauthioz N., Tschumi B., Wenes M., Marti B., Wang H., Franco F., Li W., Lopez-Mejia I.C., Fajas L., Ho P.C. et al., 2021/07. Cellular & molecular immunology, 18 (7) pp. 1761-1771. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D554C59D6F3C]
FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure.
González-Loyola A., Bovay E., Kim J., Lozano T.W., Sabine A., Renevey F., Arroz-Madeira S., Rapin A., Wypych T.P., Rota G. et al., 2021/07. Science advances, 7 (29) pp. eabf4335. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3852082D8787]
 
Healthy and Patient Type 2 Innate Lymphoid Cells are Differently Affected by in vitro Culture Conditions
Falquet Maryline, Ercolano Giuseppe, Jandus Peter, Jandus Camilla, Trabanelli Sara, 2021/07. Journal of Asthma and Allergy, Volume 14 pp. 773-783.
[DOI][WoS][Pmid][serval:BIB_60631D35A55C]
 
Hypersensitivity to platinum salts according to BRCA status in ovarian cancer: A retrospective analysis of clinical outcomes and systematic review of literature.
Giannone G., Scotto G., Katsaros D., De Giorgi U., Farolfi A., Borella F., Cosma S., Ferrero A., Mangiacotti S., Villa M. et al., 2021/07. Gynecologic oncology, 162 (1) pp. 80-87. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BD3BE28C9923]
 
Macrophage depletion induces edema through release of matrix-degrading proteases and proteoglycan deposition.
Bissinger S., Hage C., Wagner V., Maser I.P., Brand V., Schmittnaegel M., Jegg A.M., Cannarile M., Watson C., Klaman I. et al., 2021/06/16. Science translational medicine, 13 (598) pp. eabd4550. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7A2ECCA71331]
Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels.
Hernández Vásquez M.N., Ulvmar M.H., González-Loyola A., Kritikos I., Sun Y., He L., Halin C., Petrova T.V., Mäkinen T., 2021/06/15. The EMBO journal, 40 (12) pp. e107192. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4679CF9489C7]
Rate of Freeze Impacts the Survival and Immune Responses Post Cryoablation of Melanoma.
Yakkala C., Dagher J., Sempoux C., Chiang C.L., Denys A., Kandalaft L.E., Koppolu B., Duran R., 2021/06/03. Frontiers in immunology, 12 p. 695150. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_016349425533]
 
Can tumor cells take it all away?
Kohl A., Kao K.C., Ho P.C., 2021/06/01. Cell metabolism, 33 (6) pp. 1071-1072. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C38ABD4E6369]
Constant regulation for stable CD8 T-cell functional avidity and its possible implications for cancer immunotherapy.
Gilfillan C.B., Hebeisen M., Rufer N., Speiser D.E., 2021/06. European journal of immunology, 51 (6) pp. 1348-1360. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DE9645D7CF3A]
Metabolic reprogramming of terminally exhausted CD8<sup>+</sup> T cells by IL-10 enhances anti-tumor immunity.
Guo Y., Xie Y.Q., Gao M., Zhao Y., Franco F., Wenes M., Siddiqui I., Bevilacqua A., Wang H., Yang H. et al., 2021/06. Nature immunology, 22 (6) pp. 746-756. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C5D0B4808515]
Nongenetic Evolution Drives Lung Adenocarcinoma Spatial Heterogeneity and Progression.
Tavernari D., Battistello E., Dheilly E., Petruzzella A.S., Mina M., Sordet-Dessimoz J., Peters S., Krueger T., Gfeller D., Riggi N. et al., 2021/06. Cancer discovery, 11 (6) pp. 1490-1507. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F6D4BAEDCE1E]
Rapid Noninvasive Skin Monitoring by Surface Mass Recording and Data Learning.
Zhu Y., Lesch A., Li X., Lin T.E., Gasilova N., Jović M., Pick H.M., Ho P.C., Girault H.H., 2021/05/24. JACS Au, 1 (5) pp. 598-611. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2FC489BC0711]
Interpretation of T cell states from single-cell transcriptomics data using reference atlases.
Andreatta M., Corria-Osorio J., Müller S., Cubas R., Coukos G., Carmona S.J., 2021/05/20. Nature communications, 12 (1) p. 2965. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BE1D257DF142]
Necrosis binding of Ac-Lys<sup>0</sup>(IRDye800CW)-Tyr<sup>3</sup>-octreotate: a consequence from cyanine-labeling of small molecules.
Stroet MCM, Dijkstra B.M., Dulfer S.E., Kruijff S., den Dunnen WFA, Kruyt FAE, Groen RJM, Seimbille Y., Panth K.M., Mezzanotte L. et al., 2021/05/10. EJNMMI research, 11 (1) p. 47. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3F91E411E24B]
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Ercolano G., Gomez-Cadena A., Dumauthioz N., Vanoni G., Kreutzfeldt M., Wyss T., Michalik L., Loyon R., Ianaro A., Ho P.C. et al., 2021/05/05. Nature communications, 12 (1) p. 2538. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_976017D4D887]
STACAS: Sub-Type Anchor Correction for Alignment in Seurat to integrate single-cell RNA-seq data.
Andreatta M., Carmona S.J., 2021/05/05. Bioinformatics, 37 (6) pp. 882-884. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D3F01C447F08]
Author Correction: Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer.
Tanyi J.L., Chiang C.L., Chiffelle J., Thierry A.C., Baumgartener P., Huber F., Goepfert C., Tarussio D., Tissot S., Torigian D.A. et al., 2021/05/04. NPJ vaccines, 6 (1) p. 68. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2126872FC2DC]
Impact of Immunotherapy on CD4 T Cell Phenotypes and Function in Cancer.
Saillard M., Cenerenti M., Romero P., Jandus C., 2021/05/04. Vaccines, 9 (5) p. 454. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A19532FDD59E]
 
At the Bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer.
Luker G.D., Yang J., Richmond A., Scala S., Festuccia C., Schottelius M., Wester H.J., Zimmermann J., 2021/05. Journal of leukocyte biology, 109 (5) pp. 969-989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_55863C1885F3]
Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.
Lancien M., Gueno L., Salle S., Merieau E., Beriou G., Nguyen T.H., Abidi A., Dilek N., Solomon P., Poschmann J. et al., 2021/05. Cancer science, 112 (5) pp. 1723-1734. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_145E54BFE34D]
 
Late-onset and long-lasting immune-related adverse events from immune checkpoint-inhibitors: An overlooked aspect in immunotherapy.
Ghisoni E., Wicky A., Bouchaab H., Imbimbo M., Delyon J., Gautron Moura B., Gérard C.L., Latifyan S., Özdemir B.C., Caikovski M. et al., 2021/05. European journal of cancer, 149 pp. 153-164. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4791AD7F437D]
 
Real-time fluorescence imaging in intraoperative decision making for cancer surgery.
Lauwerends L.J., van Driel PBAA, Baatenburg de Jong R.J., Hardillo JAU, Koljenovic S., Puppels G., Mezzanotte L., Löwik CWGM, Rosenthal E.L., Vahrmeijer A.L. et al., 2021/05. The Lancet. Oncology, 22 (5) pp. e186-e195. Peer-reviewed.
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VP2-2021: Effectiveness of PD-(L)1 inhibitors alone or in combination with platinum-doublet chemotherapy in first-line (1L) non-squamous non-small cell lung cancer (Nsq-NSCLC) with high PD-L1 expression using real-world data
Peters S., Dafni U., Perol M., Felip E., Polito L., Pal N., Ton T.G.N., Merritt D., Morris S., Stahel R.A., 2021/05. Annals of Oncology, 32 (5) pp. 687-688.
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Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer.
Xin G., Chen Y., Topchyan P., Kasmani M.Y., Burns R., Volberding P.J., Wu X., Cohn A., Chen Y., Lin C.W. et al., 2021/04. Cancer immunology research, 9 (4) pp. 454-469. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2606CDB8F028]
 
Therapeutic Targeting of the Tumor Microenvironment.
Bejarano L., Jordāo MJC, Joyce J.A., 2021/04. Cancer discovery, 11 (4) pp. 933-959. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F799CD903FA0]
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.
Georgopoulou D., Callari M., Rueda O.M., Shea A., Martin A., Giovannetti A., Qosaj F., Dariush A., Chin S.F., Carnevalli L.S. et al., 2021/03/31. Nature communications, 12 (1) p. 1998. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6CE9EEBF7E86]
Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma.
Schaller J., Hajjami H.M., Rusakiewicz S., Ioannidou K., Piazzon N., Miles A., Golshayan D., Gaide O., Hohl D., Speiser D.E. et al., 2021/03/30. Oncotarget, 12 (7) pp. 638-648. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_BF678E4FB907]
 
Novel Peptide-Based PET Probe for Non-invasive Imaging of C-X-C Chemokine Receptor Type 4 (CXCR4) in Tumors.
Trotta A.M., Aurilio M., D'Alterio C., Ieranò C., Di Martino D., Barbieri A., Luciano A., Gaballo P., Santagata S., Portella L. et al., 2021/03/25. Journal of medicinal chemistry, 64 (6) pp. 3449-3461. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0CCD89795847]
 
Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.
Merkle P.S., Trabjerg E., Hongjian S., Ferber M., Cuendet M.A., Jørgensen TJD, Luescher I., Irving M., Zoete V., Michielin O. et al., 2021/03/23. Biochemistry, 60 (11) pp. 859-872. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CF7649E47A67]
The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies.
Waman V.P., Sen N., Varadi M., Daina A., Wodak S.J., Zoete V., Velankar S., Orengo C., 2021/03/22. Briefings in bioinformatics, 22 (2) pp. 742-768. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C745D183BB85]
Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology.
Krebs F.S., Zoete V., Trottet M., Pouchon T., Bovigny C., Michielin O., 2021/03/18. NPJ precision oncology, 5 (1) p. 19. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A929D45E3DA0]
Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer.
Tanyi J.L., Chiang C.L., Chiffelle J., Thierry A.C., Baumgartener P., Huber F., Goepfert C., Tarussio D., Tissot S., Torigian D.A. et al., 2021/03/15. NPJ vaccines, 6 (1) p. 36. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8E270F9DEDE8]
 
Women in cancer research and oncology.
Joyce J., Wakelee H., Davis M.B., Teo S.H., Bell S., Rendo V., 2021/03/08. Cancer cell, 39 (3) pp. 285-287. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E120F0EF1E3]
Abscopal effect in a patient with malignant pleural mesothelioma treated with palliative radiotherapy and pembrolizumab.
Mampuya W.A., Bouchaab H., Schaefer N., Kinj R., La Rosa S., Letovanec I., Ozsahin M., Bourhis J., Coukos G., Peters S. et al., 2021/03. Clinical and translational radiation oncology, 27 pp. 85-88. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C82F89BA6EDB]
 
Acquired haemophilia A in the postpartum and risk of relapse in subsequent pregnancies: A systematic literature review.
Dewarrat N., Gavillet M., Angelillo-Scherrer A., Naveiras O., Grandoni F., Tsakiris D.A., Alberio L., Blum S., 2021/03. Haemophilia, 27 (2) pp. 199-210. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C7857B4FC41A]
CTLA-4 blockade drives loss of T<sub>reg</sub> stability in glycolysis-low tumours.
Zappasodi R., Serganova I., Cohen I.J., Maeda M., Shindo M., Senbabaoglu Y., Watson M.J., Leftin A., Maniyar R., Verma S. et al., 2021/03. Nature, 591 (7851) pp. 652-658. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_73853A7202A4]
 
Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.
Hong A., Piva M., Liu S., Hugo W., Lomeli S.H., Zoete V., Randolph C.E., Yang Z., Wang Y., Lee J.J. et al., 2021/03. Cancer discovery, 11 (3) pp. 714-735. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_642840149803]
 
Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice.
Gaspar N., Walker J.R., Zambito G., Marella-Panth K., Lowik C., Kirkland T.A., Mezzanotte L., 2021/03. Journal of photochemistry and photobiology. B, Biology, 216 p. 112128. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_66BBF8FB0FE3]
 
Lactate modulation of immune responses in inflammatory versus tumour microenvironments.
Certo M., Tsai C.H., Pucino V., Ho P.C., Mauro C., 2021/03. Nature reviews. Immunology, 21 (3) pp. 151-161. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EEC32C274BAF]
VEGFR Inhibitors for Uterine Metastatic Perivascular Epithelioid Tumors (PEComa) Resistant to mTOR Inhibitors. A Case Report and Review of Literature.
Liapi A., Mathevet P., Herrera F.G., Hastir D., Sarivalasis A., 2021/03. Frontiers in oncology, 11 p. 641376. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0F71532CFC6B]
Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Röhrig U.F., Majjigapu S.R., Reynaud A., Pojer F., Dilek N., Reichenbach P., Ascencao K., Irving M., Coukos G., Vogel P. et al., 2021/02/25. Journal of medicinal chemistry, 64 (4) pp. 2205-2227. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3FC8F8F2B6EC]
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting.
Schmidt J., Smith A.R., Magnin M., Racle J., Devlin J.R., Bobisse S., Cesbron J., Bonnet V., Carmona S.J., Huber F. et al., 2021/02/16. Cell reports. Medicine, 2 (2) p. 100194. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9AA90BD897A9]
Anti-Ly6G binding and trafficking mediate positive neutrophil selection to unleash the anti-tumor efficacy of radiation therapy.
Boivin G., Ancey P.B., Vuillefroy de Silly R., Kalambaden P., Contat C., Petit B., Ollivier J., Bourhis J., Meylan E., Vozenin M.C., 2021/02/08. Oncoimmunology, 10 (1) p. 1876597. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_62EF59F96B75]
Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients.
de Jonge K., Tillé L., Lourenco J., Maby-El Hajjami H., Nassiri S., Racle J., Gfeller D., Delorenzi M., Verdeil G., Baumgaertner P. et al., 2021/02/02. Oncoimmunology, 10 (1) p. 1873585. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A6249CF0D69F]
 
Development and aging of the lymphatic vascular system.
González-Loyola A., Petrova T.V., 2021/02. Advanced drug delivery reviews, 169 pp. 63-78. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_24BBE73AFB66]
 
Gain of HIF1 Activity and Loss of miRNA let-7d Promote Breast Cancer Metastasis to the Brain via the PDGF/PDGFR Axis.
Wyss C.B., Duffey N., Peyvandi S., Barras D., Martinez Usatorre A., Coquoz O., Romero P., Delorenzi M., Lorusso G., Rüegg C., 2021/02/01. Cancer research, 81 (3) pp. 594-605. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_96CE02E1BF45]
Neuregulin-1 alleviate oxidative stress and mitigate inflammation by suppressing NOX4 and NLRP3/caspase-1 in myocardial ischaemia-reperfusion injury.
Wang F., Wang H., Liu X., Yu H., Huang X., Huang W., Wang G., 2021/02. Journal of cellular and molecular medicine, 25 (3) pp. 1783-1795. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_85C88F4C85DE]
Optimized gene engineering of murine CAR-T cells reveals the beneficial effects of IL-15 coexpression.
Lanitis E., Rota G., Kosti P., Ronet C., Spill A., Seijo B., Romero P., Dangaj D., Coukos G., Irving M., 2021/02/01. The Journal of experimental medicine, 218 (2) pp. e20192203. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_75DE24FE756B]
Severe COVID-19 patients exhibit an ILC2 NKG2D<sup>+</sup> population in their impaired ILC compartment.
Gomez-Cadena A., Spehner L., Kroemer M., Khelil M.B., Bouiller K., Verdeil G., Trabanelli S., Borg C., Loyon R., Jandus C., 2021/02. Cellular & molecular immunology, 18 (2) pp. 484-486. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C1457954C261]
Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis.
Ma M., Ghosh S., Tavernari D., Katarkar A., Clocchiatti A., Mazzeo L., Samarkina A., Epiney J., Yu Y.R., Ho P.C. et al., 2021/02/01. The Journal of experimental medicine, 218 (2) pp. e20201137. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3B2A745CA757]
Tumor-Associated Microbiome: Where Do We Stand?
Oliva M., Mulet-Margalef N., Ochoa-De-Olza M., Napoli S., Mas J., Laquente B., Alemany L., Duell E.J., Nuciforo P., Moreno V., 2021/02/01. International journal of molecular sciences, 22 (3) p. 1446. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BC233AA8DB1]
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer.
Cachot A., Bilous M., Liu Y.C., Li X., Saillard M., Cenerenti M., Rockinger G.A., Wyss T., Guillaume P., Schmidt J. et al., 2021/02. Science advances, 7 (9) pp. eabe3348. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7FDE10B2A046]
 
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.
Alon S., Goodwin D.R., Sinha A., Wassie A.T., Chen F., Daugharthy E.R., Bando Y., Kajita A., Xue A.G., Marrett K. et al., 2021/01/29. Science, 371 (6528). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F042AC6C0E34]
 
Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging.
Zambito G., Hall M.P., Wood M.G., Gaspar N., Ridwan Y., Stellari F.F., Shi C., Kirkland T.A., Encell L.P., Löwik C. et al., 2021/01/22. iScience, 24 (1) p. 101986. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C5B445E71AF6]
 
The double life of TLR2.
Mahfoud S., Petrova T.V., 2021/01/19. Science signaling, 14 (666) pp. eabf4701. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B238141D630E]
Impact of DOTA Conjugation on Pharmacokinetics and Immunoreactivity of [177Lu]Lu-1C1m-Fc, an Anti TEM-1 Fusion Protein Antibody in a TEM-1 Positive Tumor Mouse Model.
Delage J.A., Faivre-Chauvet A., Barbet J., Fierle J.K., Schaefer N., Coukos G., Viertl D., Dunn S.M., Gnesin S., Prior J.O., 2021/01/13. Pharmaceutics, 13 (1) p. 96. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_28C0A40301A0]
 
Biological evaluation of new TEM1 targeting recombinant antibodies for radioimmunotherapy: In vitro, in vivo and in silico studies.
D'Onofrio A., Gano L., Melo R., Mendes F., Oliveira M.C., Denoël T., Schaefer N., Viertl D., Fierle J., Coukos G. et al., 2021/01. European journal of pharmaceutics and biopharmaceutics, 158 pp. 233-244. Peer-reviewed.
[DOI][Pmid][serval:BIB_95FD98ADDB6D]
Cell therapies in ovarian cancer.
Sarivalasis A., Morotti M., Mulvey A., Imbimbo M., Coukos G., 2021. Therapeutic advances in medical oncology, 13 p. 17588359211008399. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_10D5AD530F84]
CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.
Forlani G., Michaux J., Pak H., Huber F., Marie Joseph E.L., Ramia E., Stevenson B.J., Linnebacher M., Accolla R.S., Bassani-Sternberg M., 2021. Molecular & cellular proteomics, 20 p. 100032. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_848F6AADEDBE]
 
Computer-Aided Drug Design for Cancer Therapy
Daina Antoine, Röhrig Ute F., Zoete Vincent, 2021. pp. 386-401 dans Systems Medicine, Elsevier.
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Editorial: Memory T Cells in Chronic Infections and Tumors.
Hofmann M., Jandus C., Lee L.N., Utzschneider D.T., 2021. Frontiers in immunology, 12 p. 656010. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DED547C3EF90]
 
Efficacy of cancer vaccines in selected gynaecological breast and ovarian cancers: A 20-year systematic review and meta-analysis.
Dafni U., Martín-Lluesma S., Balint K., Tsourti Z., Vervita K., Chenal J., Coukos G., Zaman K., Sarivalasis A., Kandalaft L.E., 2021/01. European journal of cancer, 142 pp. 63-82. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D084831A838B]
 
Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.
Litovchenko M., Meireles-Filho ACA, Frochaux M.V., Bevers RPJ, Prunotto A., Anduaga A.M., Hollis B., Gardeux V., Braman V.S., Russeil JMC et al., 2021/01. Science advances, 7 (5) pp. eabc3781. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DD598AB6CFE4]
Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society.
Lucas S., Tencerova M., von der Weid B., Andersen T.L., Attané C., Behler-Janbeck F., Cawthorn W.P., Ivaska K.K., Naveiras O., Podgorski I. et al., 2021. Frontiers in endocrinology, 12 p. 744527. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C15C8E462E06]
 
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.
Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A. et al., 2021/01. Autophagy, 17 (1) pp. 1-382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_345DDF9FE897]
Immune Checkpoint and Telomerase Crosstalk Is Mediated by miRNA-138 in Bladder Cancer.
El Ahanidi H., El Azzouzi M., Hafidi Alaoui C., Tetou M., Bensaid M., Chaoui I., Benbacer L., Hassan I., Oukabli M., Michaud K. et al., 2021. Frontiers in oncology, 11 p. 795242. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3DD67FC130B6]
In Vivo Evaluation of Gallium-68-Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors.
Stroet MCM, de Blois E., Haeck J., Seimbille Y., Mezzanotte L., de Jong M., Löwik CWGM, Panth K.M., 2021. Contrast media & molecular imaging, 2021 p. 2853522. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_475468701436]
Sensitive Immunopeptidomics by Leveraging Available Large-Scale Multi-HLA Spectral Libraries, Data-Independent Acquisition, and MS/MS Prediction.
Pak H., Michaux J., Huber F., Chong C., Stevenson B.J., Müller M., Coukos G., Bassani-Sternberg M., 2021. Molecular & cellular proteomics, 20 p. 100080. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DCFCF966CE50]
SMARCA4-Deficient Carcinoma of Uterine Cervix Resembling SCCOHT-Case Report.
Sirák I., Laco J., Vošmiková H., Mell L.K., Herrera F.G., Šenkeříková M., Vošmik M., 2021. Pathology oncology research, 27 p. 1610003. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A02C55D57CF2]
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications.
Ortiz R., Perazzoli G., Cabeza L., Jiménez-Luna C., Luque R., Prados J., Melguizo C., 2021. Current neuropharmacology, 19 (4) pp. 513-537. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5731184354D4]
The Promise of Personalized TCR-Based Cellular Immunotherapy for Cancer Patients.
Arnaud M., Bobisse S., Chiffelle J., Harari A., 2021. Frontiers in immunology, 12 p. 701636. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_132C3057D946]
Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients.
Bibert S., Guex N., Lourenco J., Brahier T., Papadimitriou-Olivgeris M., Damonti L., Manuel O., Liechti R., Götz L., Tschopp J. et al., 2021. Frontiers in immunology, 12 p. 666163. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_91CEC9119F7E]
UCell: Robust and scalable single-cell gene signature scoring.
Andreatta M., Carmona S.J., 2021. Computational and structural biotechnology journal, 19 pp. 3796-3798. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ADC3FAC598DC]
Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery.
Baumgaertner P., Sankar M., Herrera F.G, Benedetti F., Barras D., Thierry A.C., Dangaj D., Kandalaft L.E., Coukos G., Xenarios I. et al., 2021. Frontiers in immunology, 12 p. 633910. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E707FFE34C52]
2020
 
Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment.
Gannon P.O., Harari A., Auger A., Murgues C., Zangiacomi V., Rubin O., Ellefsen Lavoie K., Guillemot L., Navarro Rodrigo B., Nguyen-Ngoc T. et al., 2020/12. Cytotherapy, 22 (12) pp. 780-791. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_30851676B0A7]
 
Disturbed mitochondrial dynamics in CD8<sup>+</sup> TILs reinforce T cell exhaustion.
Yu Y.R., Imrichova H., Wang H., Chao T., Xiao Z., Gao M., Rincon-Restrepo M., Franco F., Genolet R., Cheng W.C. et al., 2020/12. Nature immunology, 21 (12) pp. 1540-1551. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_89908ED24FA7]
Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging.
Zambito G., Gaspar N., Ridwan Y., Hall M.P., Shi C., Kirkland T.A., Encell L.P., Löwik C., Mezzanotte L., 2020/12. Molecular imaging and biology, 22 (6) pp. 1523-1531. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1FD4332877FF]
Genomic and transcriptomic landscape of conjunctival melanoma.
Cisarova K., Folcher M., El Zaoui I., Pescini-Gobert R., Peter V.G., Royer-Bertrand B., Zografos L., Schalenbourg A., Nicolas M., Rimoldi D. et al., 2020/12. PLoS genetics, 16 (12) pp. e1009201. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4F66F37907D8]
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes
Chong Chloe, Müller Markus, Pak HuiSong, Harnett Dermot, Huber Florian, Grun Delphine, Leleu Marion, Auger Aymeric, Arnaud Marion, Stevenson Brian J. et al., 2020/12. Nature Communications, 11 (1). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_03EA897A1141]
Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes.
Pesce S., Trabanelli S., Di Vito C., Greppi M., Obino V., Guolo F., Minetto P., Bozzo M., Calvi M., Zaghi E. et al., 2020/11/25. Cancers, 12 (12) pp. E3504. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_96E040FC6BB3]
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.
Pais Ferreira D., Silva J.G., Wyss T., Fuertes Marraco S.A., Scarpellino L., Charmoy M., Maas R., Siddiqui I., Tang L., Joyce J.A. et al., 2020/11/17. Immunity, 53 (5) pp. 985-1000.e11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A0FD9237651F]
Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Shang M., Cappellesso F., Amorim R., Serneels J., Virga F., Eelen G., Carobbio S., Rincon M.Y., Maechler P., De Bock K. et al., 2020/11. Nature, 587 (7835) pp. 626-631. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3434B6E6C298]
Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment.
Zoetemelk M., Ramzy G.M., Rausch M., Koessler T., van Beijnum J.R., Weiss A., Mieville V., Piersma S.R., de Haas R.R., Delucinge-Vivier C. et al., 2020/11. Molecular oncology, 14 (11) pp. 2894-2919. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6B1C1DF10DF7]
 
Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Devlin J.R., Alonso J.A., Ayres C.M., Keller GLJ, Bobisse S., Vander Kooi C.W., Coukos G., Gfeller D., Harari A., Baker B.M., 2020/11. Nature chemical biology, 16 (11) pp. 1269-1276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_186F0AD1C570]
Transgenic CD8αβ co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells.
Bajwa G., Lanz I., Cardenas M., Brenner M.K., Arber C., 2020/11. Journal for immunotherapy of cancer, 8 (2) pp. e001487. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FD8350547BA6]
 
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Wells D.K., van Buuren M.M., Dang K.K., Hubbard-Lucey V.M., Sheehan KCF, Campbell K.M., Lamb A., Ward J.P., Sidney J., Blazquez A.B. et al., 2020/10/29. Cell, 183 (3) pp. 818-834.e13. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F6095670EC38]
Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology.
Krebs F.S., Gérard C., Wicky A., Aedo-Lopez V., Missiaglia E., Bisig B., Trimech M., Michielin O., Homicsko K., Zoete V., 2020/10/28. International journal of molecular sciences, 21 (21) pp. E8021. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_44F221AEB60A]
 
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.
Valiente M., Van Swearingen AED, Anders C.K., Bairoch A., Boire A., Bos P.D., Cittelly D.M., Erez N., Ferraro G.B., Fukumura D. et al., 2020/10/15. Cancer Research, 80 (20) pp. 4314-4323. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_47CE3A073F78]
 
All systems go: converging synthetic biology and combinatorial treatment for CAR-T cell therapy.
Lanitis E., Coukos G., Irving M., 2020/10. Current opinion in biotechnology, 65 pp. 75-87. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_97CF39EFF89C]
 
Are dendritic cells the most appropriate therapeutic vaccine for patients with ovarian cancer?
Martin-Lluesma S., Graciotti M., Grimm A.J., Boudousquié C., Chiang C.L., Kandalaft L.E., 2020/10. Current opinion in biotechnology, 65 pp. 190-196. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4448266B5C3F]
 
Biotechnologies to tackle the challenge of neoantigen identification.
Arnaud M., Duchamp M., Bobisse S., Renaud P., Coukos G., Harari A., 2020/10. Current opinion in biotechnology, 65 pp. 52-59. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_78FA51F85D77]
 
Challenges and advantages of cell therapy manufacturing under Good Manufacturing Practices within the hospital setting.
Iancu E.M., Kandalaft L.E., 2020/10. Current opinion in biotechnology, 65 pp. 233-241. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B35118F36861]
 
Cryoablation and immunotherapy of cancer.
Yakkala C., Denys A., Kandalaft L., Duran R., 2020/10. Current opinion in biotechnology, 65 pp. 60-64. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FF3698E414D7]
 
Editorial overview: Pharmaceutical biotechnology: new frontiers in cancer immunotherapy.
Kandalaft L.E., Graciotti M., 2020/10. Current opinion in biotechnology, 65 pp. iii-v. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F4B29364362]
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