Service de pharmacologie clinique

Equipe principale
Publications | Mémoires et thèses

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630 publications

... | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | ...
Physiologically-Based Pharmacokinetic Modeling Combined with Swiss HIV Cohort Study Data Supports No Dose Adjustment of Bictegravir in Elderly Individuals Living With HIV.
Stader F., Courlet P., Decosterd L.A., Battegay M., Marzolini C., 2021/04. Clinical pharmacology and therapeutics, 109 (4) pp. 1025-1029. Peer-reviewed.
Vaccine Willingness and Impact of the COVID-19 Pandemic on Women's Perinatal Experiences and Practices-A Multinational, Cross-Sectional Study Covering the First Wave of the Pandemic.
Ceulemans M., Foulon V., Panchaud A., Winterfeld U., Pomar L., Lambelet V., Cleary B., O'Shaughnessy F., Passier A., Richardson J.L. et al., 2021/03/24. International journal of environmental research and public health, 18 (7) p. 3367. Peer-reviewed.
 
A Hyaluronic Acid Hydrogel Loaded with Gentamicin and Vancomycin Successfully Eradicates Chronic Methicillin-Resistant Staphylococcus aureus Orthopedic Infection in a Sheep Model.
Boot W., Schmid T., D'Este M., Guillaume O., Foster A., Decosterd L., Richards R.G., Eglin D., Zeiter S., Moriarty T.F., 2021/03/18. Antimicrobial agents and chemotherapy, 65 (4) pp. e01840-20. Peer-reviewed.
Pharmacokinetic/Pharmacodynamic Modelling to Describe the Cholesterol Lowering Effect of Rosuvastatin in People Living with HIV.
Courlet P., Guidi M., Alves Saldanha S., Stader F., Traytel A., Cavassini M., Stoeckle M., Buclin T., Marzolini C., Decosterd L.A. et al., 2021/03. Clinical pharmacokinetics, 60 (3) pp. 379-390. Peer-reviewed.
 
Pregnancy outcome following first-trimester exposure to fingolimod: A collaborative ENTIS study.
Pauliat E., Onken M., Weber-Schoendorfer C., Rousson V., Addor M.C., Baud D., Théaudin M., Diav-Citrin O., Cottin J., Agusti A. et al., 2021/03. Multiple sclerosis, 27 (3) pp. 475-478. Peer-reviewed.
 
Prescribing in COVID-19 patients: Should we take into account inflammation?
Marzolini C., Battegay M., Sendi P., Back D. J., 2021/03. Br J Clin Pharmacol, 87 (3) pp. 719-721. Peer-reviewed.
Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment
Marra F., Smolders E. J., El-Sherif O., Boyle A., Davidson K., Sommerville A. J., Marzolini C., Siccardi M., Burger D., Gibbons S. et al., 2021/03. Drugs R D, 21 (1) pp. 9-27. Peer-reviewed.
Stabilization of urinary biogenic amines measured in clinical chemistry laboratories.
Eugster P.J., Centeno C., Dunand M., Seghezzi C., Grouzmann E., 2021/03. Clinica chimica acta; international journal of clinical chemistry, 514 pp. 24-28. Peer-reviewed.
Valproate in pregnancy: authors' reply.
Spoendlin J., Blozik E., Graber S., Rauch M., Marxer C., Ruegg S., Meier C., Winterfeld U., Panchaud A., 2021/02/15. Swiss medical weekly, 151 pp. w20481. Peer-reviewed.
 
Analysis of inappropriate prescribing in elderly patients of the Swiss HIV Cohort Study reveals gender inequity.
Livio F., Deutschmann E., Moffa G., Rrustemi F., Stader F., Elzi L., Braun D.L., Calmy A., Hachfeld A., Cavassini M. et al., 2021/02/11. The Journal of antimicrobial chemotherapy, 76 (3) pp. 758-764. Peer-reviewed.
 
Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug-Drug Interaction Magnitudes in the Elderly.
Stader F., Courlet P., Kinvig H., Penny M.A., Decosterd L.A., Battegay M., Siccardi M., Marzolini C., 2021/02. Clinical pharmacology and therapeutics, 109 (2) pp. 471-484. Peer-reviewed.
 
Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation.
Stader F., Courlet P., Kinvig H., Battegay M., Decosterd L.A., Penny M.A., Siccardi M., Marzolini C., 2021/02. British journal of clinical pharmacology, 87 (2) pp. 458-470. Peer-reviewed.
 
Impact of obesity with or without hypertension on systemic haemodynamic and renal responses to lower body negative pressure.
Vakilzadeh N., Petrovic D., Maillard M., Favre L., Grouzmann E., Wuerzner G., 2021/02. Blood pressure, 30 (1) pp. 67-74. Peer-reviewed.
Liaisons dangereuses?
Buclin T., 2021/02/01..
Sex Differences in Lopinavir Concentrations and Occurrence of Marked QTc Prolongation Episodes in Patients with COVID-19
Marzolini C., Stader F., Leuppi-Taegtmeyer A., Stoeckle M., Battegay M., Sendi P., 2021/02. Drug Saf, 44 (2) pp. 255-257. Peer-reviewed.
Pharmacovigilance [Pharmacovigilance update]
Ekobena P., Ivanyuk A., Livio F., 2021/01/13. Revue medicale suisse, 17 (720-1) pp. 80-84. Peer-reviewed.
The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation.
Abid K., Popovic M.B., Bourloud K.B., Schoumans J., Grand-Guillaume J., Grouzmann E., Mühlethaler-Mottet A., 2021/01/05. Oncotarget, 12 (1) pp. 49-60. Peer-reviewed.
Cardiovascular adverse effects of lopinavir/ritonavir and hydroxychloroquine in COVID-19 patients: Cases from a single pharmacovigilance centre
Istampoulouoglou I., Zimmermanns B., Grandinetti T., Marzolini C., Harings-Kaim A., Koechlin-Lemke S., Scholz I., Bassetti S., Leuppi-Taegtmeyer A. B., 2021. Glob Cardiol Sci Pract, 2021 (2) pp. e202111. Peer-reviewed.
Case Report: Colchicine Toxicokinetic Analysis in a Poisoned Child Requiring Extracorporeal Life Support.
Pérez Marín M., Prod'hom S., de Villiers S.F., Ferry T., Amiet V., Natterer J., Perez M.H., Buclin T., Chtioui H., Longchamp D., 2021. Frontiers in pediatrics, 9 p. 658347. Peer-reviewed.
COVID-19 treatment in patients with comorbidities: Awareness of drug-drug interactions
Back D., Marzolini C., Hodge C., Marra F., Boyle A., Gibbons S., Burger D., Khoo S., 2021/01. Br J Clin Pharmacol, 87 (1) pp. 212-213. Peer-reviewed.
Elevated acute phase proteins affect pharmacokinetics in COVID-19 trials: Lessons from the CounterCOVID - imatinib study.
Bartelink I.H., Bet P.M., Widmer N., Guidi M., Duijvelaar E., Grob B., Honeywell R., Evelo A., Tielbeek IPE, Snape S.D. et al., 2021. CPT, 10 (12) pp. 1497-1511. Peer-reviewed.
Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance
Mari A., Roloff T., Stange M., Sogaard K. K., Asllanaj E., Tauriello G., Alexander L. T., Schweitzer M., Leuzinger K., Gensch A. et al., 2021. Microorganisms, 9 (5). Peer-reviewed.
Lactic acidosis and hyperlactatemia associated with lamivudine accumulation and sepsis in a kidney transplant recipient-a case report and review of the literature
Hollinger A., Cueni N., Marzolini C., Dickenmann M., Landmann E., Battegay M., Martinez A. E., Siegemund M., Leuppi-Taegtmeyer A., 2021. AIDS Res Ther, 18 (1) p. 56. Peer-reviewed.
No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent.
Biollaz J., Buclin T., Hildebrandt W., Décosterd L.A., Nussberger J., Swenson E.R., Bärtsch P., 2021/01/01. Journal of applied physiology, 130 (1) pp. 226-236. Peer-reviewed.
 
Optimizing oral targeted anticancer therapies study for patients with solid cancer: Protocol for a randomized controlled medication adherence program along with systematic collection and modeling of pharmacokinetic and pharmacodynamic data.
Bandiera C., Cardoso E., Locatelli I., Digklia A., Zaman K., Diciolla A., Cristina V., Stravodimou A., Lopez V.A., Dolcan A. et al., 2021. JMIR research protocols, 10 (6) pp. e30090. Peer-reviewed.
 
Recognition and management of clinically significant drug-drug interactions between antiretrovirals and co-medications in a cohort of people living with HIV in rural Tanzania: a prospective questionnaire-based study
Kuemmerle A., Sikalengo G., Vanobberghen F., Ndege R. C., Foe G., Schlaeppi C., Burri C., Battegay M., Paris D. H., Glass T. R. et al., 2021. J Antimicrob Chemother, 76 (10) pp. 2681-2689. Peer-reviewed.
Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data.
Spoendlin J., Blozik E., Graber S., Rauch M., Marxer C., Rüegg S., Meier C., Winterfeld U., Panchaud A., 2021/01/01. Swiss medical weekly, 151 pp. w20386. Peer-reviewed.
 
Pharmacokinetics of Anti-Infective Agents During CytoSorb Hemoadsorption: An Experimental Study
Antoine Schneider, Pascal André, Joerg Scheier, Monika Schmidt, Heiko Ziervogel, Thierry Buclin, Detlef Kindgen-Milles, 2020/12/30..
 
Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis.
Louis-Dit-Picard H., Kouranti I., Rafael C., Loisel-Ferreira I., Chavez-Canales M., Abdel-Khalek W., Argaiz E.R., Baron S., Vacle S., Migeon T. et al., 2020/12/01. The Journal of clinical investigation, 130 (12) pp. 6379-6394. Peer-reviewed.
Pharmacogénomique et aide à la prescription médicamenteuse [Pharmacogenomics : a toolbox to improve drug prescription]
Jaccard E., Redin C., Girardin F., Waeber G., Fellay J., Vollenweider P., 2020/11/25. Revue medicale suisse, 16 (716) pp. 2259-2263. Peer-reviewed.
Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial.
Smit M., Marinosci A., Nicoletti G.J., Perneger T., Ragozzino S., Andrey D.O., Stoeckle M., Jacquerioz F., Lebowitz D., Agoritsas T. et al., 2020/11/12. BMJ open, 10 (11) pp. e040110. Peer-reviewed.
Validation and clinical application of a multiplex high performance liquid chromatography - tandem mass spectrometry assay for the monitoring of plasma concentrations of 12 antibiotics in patients with severe bacterial infections.
Decosterd L.A., Mercier T., Ternon B., Cruchon S., Guignard N., Lahrichi S., Pesse B., Rochat B., Burger R., Lamoth F. et al., 2020/11/10. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1157 p. 122160. Peer-reviewed.
2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0.
Ryom L., Cotter A., De Miguel R., Béguelin C., Podlekareva D., Arribas J.R., Marzolini C., Mallon P., Rauch A., Kirk O. et al., 2020/11. HIV medicine, 21 (10) pp. 617-624. Peer-reviewed.
Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial.
Sculier D., Wandeler G., Yerly S., Marinosci A., Stoeckle M., Bernasconi E., Braun D.L., Vernazza P., Cavassini M., Buzzi M. et al., 2020/11. PLoS medicine, 17 (11) pp. e1003421. Peer-reviewed.
 
Emicizumab-Induced Seronegative Full-House Lupus Nephritis in a Child.
Chehade H., Cachat F., Beck-Popovic M., Rotman S., Diezi L., Albisetti M., Alberio L., Young G., Rizzi M., 2020/11. Pediatrics, 146 (5) pp. e20200123. Peer-reviewed.
Les étudiant·e·s en médecine mènent une recherche dans la communauté
Daeppen J.B., Gaume J., Bodenmann P., Buclin T., Fauvel A., Paroz S., Widmer D., Baumann M., 2020/10/21. Revue medicale suisse, 16 (711) p. 2007.
Drug-Drug Interactions with Antiretroviral Drugs in Pregnant Women Living with HIV: Are They Different from Non-Pregnant Individuals?
Bukkems V. E., Colbers A., Marzolini C., Molto J., Burger D. M., 2020/10. Clin Pharmacokinet, 59 (10) pp. 1217-1236. Peer-reviewed.
Hepatocellular type II fibrinogen inclusions in a patient with severe COVID-19 and hepatitis.
Fraga M., Moradpour D., Artru F., Romailler E., Tschopp J., Schneider A., Chtioui H., Neerman-Arbez M., Casini A., Alberio L. et al., 2020/10. Journal of hepatology, 73 (4) pp. 967-970. Peer-reviewed.
 
Management of erroneous subcutaneous injection of vincristine.
de Goycoechea D., Dewarrat N., Rothuizen L.E., Matter M., Nagy M., Locher G., Spertini O., Blum S., 2020/10. Leukemia & lymphoma, 61 (10) pp. 2530-2532. Peer-reviewed.
 
Potentially inappropriate medications in older adults living with HIV
Lopez-Centeno B., Badenes-Olmedo C., Mataix-Sanjuan A., Bellon J. M., Perez-Latorre L., Lopez J. C., Benedi J., Khoo S., Marzolini C., Calvo-Alcantara M. J. et al., 2020/09. HIV Med, 21 (8) pp. 541-546. Peer-reviewed.
 
Progressive multifocal leukoencephalopathy responsive to withdrawal of imatinib in a patient with FIP1L1-PDGFRA positive myeloid neoplasm.
Blum S., Dunet V., Comoli P., Tirefort Y., Chalandon Y., Opota O., Comte D., Spertini O., Livio F., Brouland J.P. et al., 2020/09. Leukemia & lymphoma, 61 (9) pp. 2226-2229. Peer-reviewed.
A new <sup>68</sup>Ga-labeled somatostatin analog containing two iodo-amino acids for dual somatostatin receptor subtype 2 and 5 targeting.
Mansi R., Abid K., Nicolas G.P., Del Pozzo L., Grouzmann E., Fani M., 2020/08/05. EJNMMI research, 10 (1) p. 90. Peer-reviewed.
 
A population pharmacokinetic model for escitalopram and its major metabolite in depressive patients during the perinatal period: Prediction of infant drug exposure through breast milk.
Weisskopf E., Guidi M., Fischer C.J., Bickle Graz M., Beaufils E., Nguyen K.A., Morisod Harari M., Rouiller S., Rothenburger S., Gaucherand P. et al., 2020/08. British journal of clinical pharmacology, 86 (8) pp. 1642-1653. Peer-reviewed.
 
Commentary on A Rare and Unusual Cause of Unilateral Ureteric Obstruction in a Child.
Grouzmann E., 2020/08/01. Clinical chemistry, 66 (8) pp. 1010-1011. Peer-reviewed.
Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV.
Courlet P., Decosterd L.A., Alves Saldanha S., Cavassini M., Stader F., Stoeckle M., Buclin T., Marzolini C., Csajka C., Guidi M. et al., 2020/08. Clinical pharmacokinetics, 59 (8) pp. 1037-1048. Peer-reviewed.
Optimization of a Py-GC/MS method for silicone-based lubricants analysis
Maurer Jonathan, Buffaz Kévin, Massonnet Geneviève, Roussel Christophe, Burnier Céline, 2020/08. Journal of Analytical and Applied Pyrolysis, 149 p. 104861.
 
Population Pharmacokinetics of Erlotinib in Patients With Non-small Cell Lung Cancer: Its Application for Individualized Dosing Regimens in Older Patients.
Cardoso E., Guidi M., Khoudour N., Boudou-Rouquette P., Fabre E., Tlemsani C., Arrondeau J., Goldwasser F., Vidal M., Schneider M.P. et al., 2020/07. Clinical therapeutics, 42 (7) pp. 1302-1316. Peer-reviewed.
 
Real-life management of drug-drug interactions between antiretrovirals and statins.
Courlet P., Livio F., Alves Saldanha S., Scherrer A., Battegay M., Cavassini M., Stoeckle M., Decosterd L.A., Marzolini C., Swiss HIV Cohort Study, 2020/07/01. The Journal of antimicrobial chemotherapy, 75 (7) pp. 1972-1980. Peer-reviewed.
Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.
Courlet P., Alves Saldanha S., Cavassini M., Marzolini C., Choong E., Csajka C., Günthard H.F., André P., Buclin T., Desfontaine V. et al., 2020/06. Journal of mass spectrometry, 55 (6) pp. e4506. Peer-reviewed.
An international registry for emergent pathogens and pregnancy.
Panchaud A., Favre G., Pomar L., Vouga M., Aebi-Popp K., Baud D., COVI-Preg group, 2020/05/09. Lancet, 395 (10235) pp. 1483-1484. Peer-reviewed.
 
Aging does not impact drug--drug interaction magnitudes with antiretrovirals.
Stader F., Decosterd L., Stoeckle M., Cavassini M., Battegay M., Saldanha S.A., Marzolini C., Courlet P., and the Swiss HIV Cohort Study, 2020/05/01. AIDS, 34 (6) pp. 949-952. Peer-reviewed.
Cobicistat: A case of mislabelled drug-drug interaction risk?
Burger D. M., Calmy A., Marzolini C., 2020/05. Br J Clin Pharmacol, 86 (5) pp. 834-836. Peer-reviewed.
 
New Drugs for NASH and HIV Infection: Great Expectations for a Great Need
Guaraldi G., Maurice J. B., Marzolini C., Monteith K., Milic J., Tsochatzis E., Bhagani S., Morse C. G., Price J. C., Ingiliz P. et al., 2020/05. Hepatology, 71 (5) pp. 1831-1844. Peer-reviewed.
Traitements aggravant une infection par le COVID-19 : vraiment ? [Drugs that aggravate the course of COVID-19 : really ?]
Rothuizen L.E., Livio F., Buclin T., 2020/04/29. Revue medicale suisse, 16 (N° 691-2) pp. 852-854. Peer-reviewed.
Population Pharmacokinetics/Pharmacodynamics of Dabrafenib Plus Trametinib in Patients with BRAF-Mutated Metastatic Melanoma.
Balakirouchenane D., Guégan S., Csajka C., Jouinot A., Heidelberger V., Puszkiel A., Zehou O., Khoudour N., Courlet P., Kramkimel N. et al., 2020/04/09. Cancers, 12 (4). Peer-reviewed.
Optimisation of vancomycin exposure in neonates based on the best level of evidence.
Dao K., Guidi M., André P., Giannoni E., Basterrechea S., Zhao W., Fuchs A., Pfister M., Buclin T., Csajka C., 2020/04. Pharmacological research, 154 p. 104278. Peer-reviewed.
Amisulpride: Real-World Evidence of Dose Adaptation and Effect on Prolactin Concentrations and Body Weight Gain by Pharmacokinetic/Pharmacodynamic Analyses.
Glatard A., Guidi M., Delacrétaz A., Dubath C., Grosu C., Laaboub N., von Gunten A., Conus P., Csajka C., Eap C.B., 2020/03. Clinical pharmacokinetics, 59 (3) pp. 371-382. Peer-reviewed.
 
Endocrine causes of secondary hypertension.
Grouzmann E., 2020/03. Best practice & research. Clinical endocrinology & metabolism, 34 (2) p. 101419. Peer-reviewed.
 
Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly
Stader F., Kinvig H., Penny M. A., Battegay M., Siccardi M., Marzolini C., 2020/03. Clin Pharmacokinet, 59 (3) pp. 383-401. Peer-reviewed.
 
Compassionate Use of Letermovir in a 2-Year-Old Immunocompromised Child With Resistant Cytomegalovirus Disease.
Pérez Marín M., Decosterd L.A., Andre P., Buclin T., Mercier T., Murray K., Rizzi M., Meylan P., Jaton-Ogay K., Opota O. et al., 2020/02/28. Journal of the Pediatric Infectious Diseases Society, 9 (1) pp. 96-99. Peer-reviewed.
 
Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate.
Dietrich L.G., Barceló C., Thorball C.W., Ryom L., Burkhalter F., Hasse B., Furrer H., Weisser M., Steffen A., Bernasconi E. et al., 2020/02/14. Clinical infectious diseases, 70 (5) pp. 890-897. Peer-reviewed.
Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers.
Dao K., Thoueille P., Decosterd L.A., Mercier T., Guidi M., Bardinet C., Lebon S., Choong E., Castang A., Guittet C. et al., 2020/02. Pharmacology research & perspectives, 8 (1) pp. e00558. Peer-reviewed.
The challenge of HIV treatment in an era of polypharmacy
Back D., Marzolini C., 2020/02. J Int AIDS Soc, 23 (2) pp. e25449. Peer-reviewed.
 
Quantification of Neuropeptide Y and Four of Its Metabolites in Human Plasma by Micro-UHPLC-MS/MS.
Vocat C., Dunand M., Hubers S.A., Bourdillon N., Millet G.P., Brown N.J., Wuerzner G., Grouzmann E., Eugster P.J., 2020/01/07. Analytical chemistry, 92 (1) pp. 859-866. Peer-reviewed.
Bevacizumab Induced Thrombotic Microangiopathy in a 71-Year Old Glioblastoma Patient
Chevallier Mathieu, Girardin Francois, Mirlesse Nicolas, Koessler Thibaud, 2020. Clinics of Oncology, 03 (01).
Drug interactions: a review of the unseen danger of experimental COVID-19 therapies
Hodge D., Marra F., Marzolini C., Boyle A., Gibbons S., Siccardi M., Burger D., Back D., Khoo S., 2020. J Antimicrob Chemother, 75 (12) pp. 3417-3424. Peer-reviewed.
Effect of Systemic Inflammatory Response to SARS-CoV-2 on Lopinavir and Hydroxychloroquine Plasma Concentrations
Marzolini C., Stader F., Stoeckle M., Franzeck F., Egli A., Bassetti S., Hollinger A., Osthoff M., Weisser M., Gebhard C. E. et al., 2020. Antimicrob Agents Chemother, 64 (9). Peer-reviewed.
 
Fetotoxic risk of AT1 blockers exceeds that of angiotensin-converting enzyme inhibitors: an observational study.
Weber-Schoendorfer C., Kayser A., Tissen-Diabaté T., Winterfeld U., Eleftheriou G., Te Winkel B., Diav-Citrin O., Greenall A., Hoeltzenbein M., Schaefer C., 2020/01. Journal of hypertension, 38 (1) pp. 133-141. Peer-reviewed.
Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy.
Barceló C., Guidi M., Thorball C.W., Hammer C., Chaouch A., Scherrer A.U., Hasse B., Cavassini M., Furrer H., Calmy A. et al., 2020/01. Open forum infectious diseases, 7 (1) pp. ofz464. Peer-reviewed.
 
Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging people living with HIV.
Courlet P., Stader F., Guidi M., Alves Saldanha S., Stoeckle M., Cavassini M., Battegay M., Buclin T., Decosterd L.A., Marzolini C. et al., 2020/01/01. AIDS, 34 (1) pp. 103-108. Peer-reviewed.
 
Polypharmacy and Drug-Drug Interactions in People Living With Human Immunodeficiency Virus in the Region of Madrid, Spain: A Population-Based Study
Lopez-Centeno B., Badenes-Olmedo C., Mataix-Sanjuan A., McAllister K., Bellon J. M., Gibbons S., Balsalobre P., Perez-Latorre L., Benedi J., Marzolini C. et al., 2020. Clin Infect Dis, 71 (2) pp. 353-362. Peer-reviewed.
Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study
Schlaeppi C., Vanobberghen F., Sikalengo G., Glass T. R., Ndege R. C., Foe G., Kuemmerle A., Paris D. H., Battegay M., Marzolini C. et al., 2020/01. HIV Med, 21 (1) pp. 53-63. Peer-reviewed.
Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect
Stader F., Khoo S., Stoeckle M., Back D., Hirsch H. H., Battegay M., Marzolini C., 2020. J Antimicrob Chemother, 75 (10) pp. 3084-3086. Peer-reviewed.
The steps to therapeutic drug monitoring: A structured approach illustrated with imatinib
Buclin T., Thoma Y., Widmer N., André P., Guidi M., Csajka C., Decosterd L..A., 2020. Frontiers in Pharmacology, 11 p. 177. Peer-reviewed.
Therapeutic Drug Monitoring of Newer Antiepileptic Drugs: A Randomized Trial for Dosage Adjustment.
Aícua-Rapún I., André P., Rossetti A.O., Ryvlin P., Hottinger A.F., Decosterd L.A., Buclin T., Novy J., 2020/01. Annals of neurology, 87 (1) pp. 22-29. Peer-reviewed.
 
Therapeutic drug monitoring of targeted anticancer protein kinase inhibitors in routine clinical use: A critical review.
Cardoso E., Guidi M., Blanchet B., Schneider M.P., Decosterd L.A., Buclin T., Csajka C., Widmer N., 2020. Therapeutic Drug Monitoring, 42 (1) pp. 33-44. Peer-reviewed.
Combined immune checkpoint inhibitor therapy with nivolumab and ipilimumab causing acute-onset type 1 diabetes mellitus following a single administration: two case reports.
Zezza M., Kosinski C., Mekoguem C., Marino L., Chtioui H., Pitteloud N., Lamine F., 2019/12/23. BMC endocrine disorders, 19 (1) p. 144. Peer-reviewed.
 
Clinical Pharmacodynamics, Pharmacokinetics, and Drug Interaction Profile of Doravirine
Boyle A., Moss C. E., Marzolini C., Khoo S., 2019/12. Clin Pharmacokinet, 58 (12) pp. 1553-1565. Peer-reviewed.
 
Gender medicine and oncology: report and consensus of an ESMO workshop.
Wagner A.D., Oertelt-Prigione S., Adjei A., Buclin T., Cristina V., Csajka C., Coukos G., Dafni U., Dotto G.P., Ducreux M. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1914-1924. Peer-reviewed.
Polypharmacy, Drug-Drug Interactions, and Inappropriate Drugs: New Challenges in the Aging Population With HIV.
Courlet P., Livio F., Guidi M., Cavassini M., Battegay M., Stoeckle M., Buclin T., Alves Saldanha S., Csajka C., Marzolini C. et al., 2019/12. Open forum infectious diseases, 6 (12) pp. ofz531. Peer-reviewed.
 
N-of-1 trials ou essais thérapeutiques individuels : un test probant pour diagnostiquer l’efficacité thérapeutique [N-of-1 trials or single-patient therapeutic tests: evidence-based tests to diagnose therapeutic efficacy]
Diezi L., Buclin T., 2019/11/06. Revue medicale suisse, 15 (670) pp. 2058-2061. Peer-reviewed.
 
Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics
Brockhaus L., Goldblum D., Eggenschwiler L., Zimmerli S., Marzolini C., 2019/11. Clin Microbiol Infect, 25 (11) pp. 1364-1369. Peer-reviewed.
 
Noninferiority of Simplified Dolutegravir Monotherapy Compared to Continued Combination Antiretroviral Therapy That Was Initiated During Primary Human Immunodeficiency Virus Infection: A Randomized, Controlled, Multisite, Open-label, Noninferiority Trial.
Braun D.L., Turk T., Tschumi F., Grube C., Hampel B., Depmeier C., Schreiber P.W., Brugger S.D., Greiner M., Steffens D. et al., 2019/10/15. Clinical infectious diseases, 69 (9) pp. 1489-1497. Peer-reviewed.
Dipeptidyl Peptidase 4 Inhibition Increases Postprandial Norepinephrine via Substance P (NK1 Receptor) During RAAS Inhibition.
Wilson J.R., Kerman S.J., Hubers S.A., Yu C., Nian H., Grouzmann E., Eugster P.J., Mayfield D.S., Brown N.J., 2019/10/01. Journal of the Endocrine Society, 3 (10) pp. 1784-1798. Peer-reviewed.
 
Gestion du traitement de l’asthme chez une femme enceinte
Levray Andréa, Berger Jérôme, Guignard Bertrand, Beney Johnny, Csajka Chantal, Panchaud Alice, 2019/10. pharmaJournal.
 
Risk-benefit balance assessment of SSRI antidepressant use during pregnancy and lactation based on best available evidence - an update.
Fischer Fumeaux C.J., Morisod Harari M., Weisskopf E., Eap C.B., Epiney M., Vial Y., Csajka C., Bickle Graz M., Panchaud A., 2019/10. Expert opinion on drug safety, 18 (10) pp. 949-963. Peer-reviewed.
 
Therapiemanagement von Asthma bei einer schwangeren Frau
Levray Andréa, Berger Jérôme, Guignard Bertrand, Beney Johnny, Csajka Chantal, Panchaud Alice, 2019/10. pharmaJournal.
 
Escitalopram population pharmacokinetics in people living with human immunodeficiency virus and in the psychiatric population: Drug-drug interactions and probability of target attainment.
Courlet P., Guidi M., Glatard A., Alves Saldanha S., Cavassini M., Buclin T., Marzolini C., Eap C.B., Decosterd L.A., Csajka C. et al., 2019/09. British journal of clinical pharmacology, 85 (9) pp. 2022-2032. Peer-reviewed.
 
Population pharmacokinetics of dolutegravir: influence of drug-drug interactions in a real-life setting.
Barcelo C., Aouri M., Courlet P., Guidi M., Braun D.L., Günthard H.F., Piso R.J., Cavassini M., Buclin T., Decosterd L.A. et al., 2019/09/01. The Journal of antimicrobial chemotherapy, 74 (9) pp. 2690-2697. Peer-reviewed.
 
Stabilizing cumulative incidence estimation of pregnancy outcome with delayed entries.
Rousson V., Allignol A., Aurousseau A., Winterfeld U., Beyersmann J., 2019/09. Biometrical journal. Biometrische Zeitschrift, 61 (5) pp. 1290-1302. Peer-reviewed.
 
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Courlet P., Spaggiari D., Desfontaine V., Cavassini M., Alves Saldanha S., Buclin T., Marzolini C., Csajka C., Decosterd L.A., 2019/09/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1125 p. 121733. Peer-reviewed.
 
Emtricitabine and lamivudine concentrations in saliva: a simple suitable test for treatment adherence.
Courlet P., Decosterd L.A., Brown J.A., Alves Saldanha S., Marzolini C., Cavassini M., Stoeckle M., Csajka C., Labhardt N.D., Calmy A. et al., 2019/08/01. The Journal of antimicrobial chemotherapy, 74 (8) pp. 2468-2470. Peer-reviewed.
Mortality from suicide among people living with HIV and the general Swiss population: 1988-2017.
Ruffieux Y., Lemsalu L., Aebi-Popp K., Calmy A., Cavassini M., Fux C.A., Günthard H.F., Marzolini C., Scherrer A., Vernazza P. et al., 2019/08. Journal of the International AIDS Society, 22 (8) pp. e25339. Peer-reviewed.
A Comprehensive Framework for Physiologically-Based Pharmacokinetic Modeling in Matlab
Stader F., Penny M. A., Siccardi M., Marzolini C., 2019/07. CPT Pharmacometrics Syst Pharmacol, 8 (7) pp. 444-459. Peer-reviewed.
 
High concentration of plasma methoxytyramine: dopamine-producing tumour or Parkinson's disease therapy?
Chtioui H., Sadowski S.M., Winzeler B., Tschopp O., Grouzmann E., Abid K., 2019/07. Annals of clinical biochemistry, 56 (4) pp. 466-471. Peer-reviewed.
Influence of body weight and UGT2B7 polymorphism on varenicline exposure in a cohort of smokers from the general population.
Glatard A., Guidi M., Dobrinas M., Cornuz J., Csajka C., Eap C.B., 2019/07. European journal of clinical pharmacology, 75 (7) pp. 939-949. Peer-reviewed.
 
Prescribing issues in elderly individuals living with HIV.
Marzolini C., Livio F., 2019/07. Expert review of clinical pharmacology, 12 (7) pp. 643-659. Peer-reviewed.
 
Severe rosuvastatin accumulation with rhabdomyolysis due to drug interactions and low cardiac output syndrome.
Previsdomini M., Graziano E., Decosterd L., Courlet P., Perren A., Ceschi A., 2019/07. British journal of clinical pharmacology, 85 (7) pp. 1616-1618. Peer-reviewed.
 
Isavuconazole brain penetration in cerebral aspergillosis.
Lamoth F., Mercier T., André P., Pagani J.L., Pantet O., Maduri R., Guery B., Decosterd L.A., 2019/06/01. The Journal of antimicrobial chemotherapy, 74 (6) pp. 1751-1753. Peer-reviewed.
 
Défis dans la prise en charge du diabète en hémodialyse chronique [Challenges in managing diabetes in chronic hemodialysis]
Lamine F., Chtioui H., Schwotzer N., Pruijm M., Nobre D., Phan O., Ammor N., Andrey M., Grangier-Bernard P., Zanchi A., 2019/05/29. Revue medicale suisse, 15 (653) pp. 1132-1139. Peer-reviewed.
Sofosbuvir add-on to ribavirin for chronic hepatitis E in a cirrhotic liver transplant recipient: a case report.
Fraga M., Gouttenoire J., Sahli R., Chtioui H., Marcu C., Pascual M., Moradpour D., Vionnet J., 2019/05/24. BMC gastroenterology, 19 (1) p. 76. Peer-reviewed.
 
Automédication et douleur
Buclin Thierry, Diezi Léonore, Monney Aurélia, 2019/05. La Gazette médicale.
 
Clindamycin clearance during Cytosorb hemoadsorption: A case report and pharmacokinetic study.
Poli E.C., Simoni C., André P., Buclin T., Longchamp D., Perez M.H., Ferry T., Schneider A.G., 2019/05. The International journal of artificial organs, 42 (5) pp. 258-262. Peer-reviewed.
Infections aiguës des voies respiratoires et urinaires au cabinet médical : quelques traitements en médecine complémentaire [Acute respiratory and urinary tract infections in medical practice : a selection of complementary medicines]
Dumitrascu A., Senn L., Rothuizen L.E., Rodondi P.Y., 2019/04/24. Revue medicale suisse, 15 (648) pp. 875-881. Peer-reviewed.
Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children.
Guidi M., Mercier T., Aouri M., Decosterd L.A., Csajka C., Ogutu B., Carn G., Kiechel J.R., 2019/04/18. Malaria journal, 18 (1) p. 139. Peer-reviewed.
Pharmacovigilance, hémovigilance, vaccinovigilance, tératovigilance… : quelles retombées imprévues pour les patients, les intervenants de santé et les systèmes de soins ?
Buclin Thierry, Foley Rose-Anna, Livio Françoise, 2019/04/11. Anthropologie & Santé.
Cardiac Implantable Electronic Device-Related Infection Due to Granulicatella adiacens.
Sendi P., Wustmann K., Büchi A.E., Noti F., Klaeser B., Sonderegger B., Auf der Maur C., Mercier T., Schwerzmann M., Ruppen C., 2019/04. Open forum infectious diseases, 6 (4) pp. ofz130. Peer-reviewed.
 
Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes
Stader F., Siccardi M., Battegay M., Kinvig H., Penny M. A., Marzolini C., 2019/04. Clin Pharmacokinet, 58 (4) pp. 483-501. Peer-reviewed.
Complementary medicine use during cancer treatment and potential herb-drug interactions from a cross-sectional study in an academic centre.
Jermini M., Dubois J., Rodondi P.Y., Zaman K., Buclin T., Csajka C., Orcurto A., Rothuizen L.E., 2019/03/25. Scientific reports, 9 (1) p. 5078. Peer-reviewed.
 
Sub-picomolar quantification of PTH 1-34 in plasma by UHPLC-MS/MS after subcutaneous injection of teriparatide and identification of PTH 1-33, its degradation product.
Eugster P.J., Chtioui H., Herren A., Dunand M., Cappelle D., Bourquin J., Buclin T., Grouzmann E., 2019/03/20. Journal of pharmaceutical and biomedical analysis, 166 pp. 205-212. Peer-reviewed.
 
Birth Defects After Exposure to Efavirenz-Based Antiretroviral Therapy at Conception/First Trimester of Pregnancy: A Multicohort Analysis.
Winterfeld Ursula, 2019/03/01. Journal of acquired immune deficiency syndromes (1999).
 
Reply to L. Pala et al.
Wagner A.D., Özdemir B., Csajka C., 2019/02/10. Journal of clinical oncology, 37 (5) pp. 439-440. Peer-reviewed.
 
Increasing hepatitis C virus screening in people who inject drugs in Switzerland using rapid antibody saliva and dried blood spot testing: A cost-effectiveness analysis.
Girardin F., Hearmon N., Negro F., Eddowes L., Bruggmann P., Castro E., 2019/02. Journal of viral hepatitis, 26 (2) pp. 236-245. Peer-reviewed.
 
Multicenter Population Pharmacokinetic Study of Colistimethate Sodium and Colistin Dosed as in Normal Renal Function in Patients on Continuous Renal Replacement Therapy.
Leuppi-Taegtmeyer A.B., Decosterd L., Osthoff M., Mueller N.J., Buclin T., Corti N., 2019/02. Antimicrobial agents and chemotherapy, 63 (2). Peer-reviewed.
 
What is the cost of endoscopic submucosal dissection (ESD)? A medico-economic study.
Dahan M., Pauliat E., Liva-Yonnet S., Brischoux S., Legros R., Tailleur A., Carrier P., Charissoux A., Valgueblasse V., Loustaud-Ratti V. et al., 2019/02. United European gastroenterology journal, 7 (1) pp. 138-145. Peer-reviewed.
 
Pharmacovigilance [Pharmacovigilance update]
Abo Loha C., Livio F., 2019/01/09. Revue medicale suisse, 15 (N° 632-633) pp. 92-95. Peer-reviewed.
Adherence to intermittent preventive treatment for malaria in Papua New Guinean infants: A pharmacological study alongside the randomized controlled trial.
Sottas O., Guidi M., Thieffry B., Schneider M., Décosterd L., Mueller I., Genton B., Csajka C., Senn N., 2019. PloS one, 14 (2) pp. e0210789. Peer-reviewed.
Closed-loop Neuropharmacology for Epilepsy: Distant Dream or Future Reality?
Aicua-Rapun I., André P., Novy J., 2019. Current neuropharmacology, 17 (5) pp. 447-458. Peer-reviewed.
 
Current Challenges and Solutions in Research and Clinical Care of Older Persons Living with HIV: Findings Presented at the 9th International Workshop on HIV and Aging
Sundermann E. E., Erlandson K. M., Pope C. N., Rubtsova A., Montoya J., Moore A. A., Marzolini C., O'Brien K. K., Pahwa S., Payne B. A. I. et al., 2019. AIDS Res Hum Retroviruses, 35 (11-12) pp. 985-998. Peer-reviewed.
Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma.
Spaggiari D., Desfontaine V., Cruchon S., Guinchard S., Vocat A., Blattes E., Pitteloud J., Ciullini L., Bardinet C., Ivanyuk A. et al., 2019. PloS one, 14 (5) pp. e0217139. Peer-reviewed.
 
Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH.
Blanc Mettral J., Faller N., Cruchon S., Sottas L., Buclin T., Schild L., Choong E., Nahimana A., Decosterd L.A., 2019. Drug metabolism letters, 13 (2) pp. 102-110. Peer-reviewed.
Intravenous brivaracetam in status epilepticus: Correlation between loading dose, plasma levels and clinical response.
Aicua-Rapun I., André P., Rossetti A.O., Decosterd L.A., Buclin T., Novy J., 2019/01. Epilepsy research, 149 pp. 88-91. Peer-reviewed.
 
Pharmacokinetics, Placental and Breast Milk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV
Hodel E. M., Marzolini C., Waitt C., Rakhmanina N., 2019. Curr Pharm Des, 25 (5) pp. 556-576. Peer-reviewed.
 
Precision dosing of imatinib: A model-based approach to optimize achievement of target exposure
Goutelle S., Widmer N., Buclin T., Csajka C., 2019., 23e Congrès de la Société Française de Pharmacologie et de Thérapeutique p. 35 dans Fundamental & Clinical Pharmacology. Peer-reviewed.
Prescribing issues in older adults living with HIV: thinking beyond drug-drug interactions with antiretroviral drugs.
Livio F., Marzolini C., 2019. Therapeutic advances in drug safety, 10 p. 2042098619880122. Peer-reviewed.
 
Therapeutic drug monitoring (TDM)
Pascal A., Widmer N., Buclin T., 2019. pp. 1-9 dans Swiss recommendations for adult cystic fibrosis care chap. 4.2.3, RMS Editions/Médecine et Hygiène.
 
Effect of renal clearance and continuous renal replacement therapy on appropriateness of recommended meropenem dosing regimens in critically ill patients with susceptible life-threatening infections.
Burger R., Guidi M., Calpini V., Lamoth F., Decosterd L., Robatel C., Buclin T., Csajka C., Marchetti O., 2018/12/01. The Journal of antimicrobial chemotherapy, 73 (12) pp. 3413-3422. Peer-reviewed.
 
Robustness analysis of personalised delivery rate computation for IV administered anesthetic
Simalatsar Alena, Guidi Monia, Roduit Pierre, Buclin Thierry, 2018/12. Smart Health, 9-10 pp. 101-114.
Levetiracetam circulating concentrations and response in status epilepticus.
Perrenoud M., André P., Buclin T., Decosterd L.A., Rossetti A.O., Novy J., 2018/11. Epilepsy & behavior, 88 pp. 61-65. Peer-reviewed.
 
Maternal-fetal transmission and adverse perinatal outcomes in pregnant women infected with Zika virus: prospective cohort study in French Guiana.
Pomar L., Vouga M., Lambert V., Pomar C., Hcini N., Jolivet A., Benoist G., Rousset D., Matheus S., Malinger G. et al., 2018/10/31. BMJ, 363 pp. k4431. Peer-reviewed.
 
High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure.
Tyagi R.K., Gleeson P.J., Arnold L., Tahar R., Prieur E., Decosterd L., Pérignon J.L., Olliaro P., Druilhe P., 2018/10/01. BMC medicine, 16 (1) p. 181. Peer-reviewed.
 
Myoglobinuria in two patients with Duchenne muscular dystrophy after treatment with zoledronate: a case-report and call for caution.
Ivanyuk A., García Segarra N., Buclin T., Klein A., Jacquier D., Newman C.J., Bloetzer C., 2018/10. Neuromuscular disorders, 28 (10) pp. 865-867. Peer-reviewed.
 
Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring.
Tenaglia E., Ferretti A., Decosterd L.A., Werner D., Mercier T., Widmer N., Buclin T., Guiducci C., 2018/09/10. Journal of Pharmaceutical and Biomedical Analysis, 159 pp. 341-347. Peer-reviewed.
 
DPP (Dipeptidyl Peptidase)-4 Inhibition Potentiates the Vasoconstrictor Response to NPY (Neuropeptide Y) in Humans During Renin-Angiotensin-Aldosterone System Inhibition.
Hubers S.A., Wilson J.R., Yu C., Nian H., Grouzmann E., Eugster P., Shibao C.A., Billings F.T., Jafarian Kerman S., Brown N.J., 2018/09. Hypertension, 72 (3) pp. 712-719. Peer-reviewed.
Efficacy and safety of continuous infusions with elastomeric pumps for outpatient parenteral antimicrobial therapy (OPAT): an observational study.
Voumard R., Gardiol C., André P., Arensdorff L., Cochet C., Boillat-Blanco N., Decosterd L., Buclin T., de Vallière S., 2018/09/01. The Journal of antimicrobial chemotherapy, 73 (9) pp. 2540-2545. Peer-reviewed.
 
Ethical approval for multicenter cohort studies on drug exposure during pregnancy: A survey among members of the European Network of Teratology Information Services (ENTIS).
Winterfeld U., Weber-Schöndorfer C., Schaefer C., von Elm E., Buclin T., 2018/09. Reproductive toxicology, 80 pp. 68-72. Peer-reviewed.
 
Population Pharmacokinetic Study of Amoxicillin-Treated Burn Patients Hospitalized at a Swiss Tertiary-Care Center.
Fournier A., Goutelle S., Que Y.A., Eggimann P., Pantet O., Sadeghipour F., Voirol P., Csajka C., 2018/09. Antimicrobial agents and chemotherapy, 62 (9) pp. e00505-18. Peer-reviewed.
 
Sensitive quantification of the somatostatin analog AP102 in plasma by ultra-high pressure liquid chromatography-tandem mass spectrometry and application to a pharmacokinetic study in rats.
Eugster P.J., Boyle C.N., Prod'hom S., Tarasco E., Buclin T., Lutz T.A., Harris A.G., Grouzmann E., 2018/09. Drug testing and analysis, 10 (9) pp. 1448-1457. Peer-reviewed.
 
Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method.
Grouzmann E., Centeno C., Eugster P.J., 2018/08/28. Clinical chemistry and laboratory medicine, 56 (9) pp. 1533-1541. Peer-reviewed.
 
Boosted darunavir, emtricitabine and tenofovir pharmacokinetics in sthe early and late postgastric bypass surgery periods.
Baettig V., Courlet P., Delko T., Battegay M., Marzolini C., 2018/08/24. AIDS, 32 (13) pp. 1903-1905. Peer-reviewed.
 
Antiepileptika in der Stillzeit : Wie beraten wir die Mütter? [Use of antiepileptic drugs during breastfeeding : What do we tell the mother?]
Crettenand M., Rossetti A.O., Buclin T., Winterfeld U., 2018/08. Der Nervenarzt, 89 (8) pp. 913-921. Peer-reviewed.
Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications
Stader F., Kinvig H., Battegay M., Khoo S., Owen A., Siccardi M., Marzolini C., 2018/07. Antimicrob Agents Chemother, 62 (7). Peer-reviewed.
 
Association of Patient Sex With Chemotherapy-Related Toxic Effects: A Retrospective Analysis of the PETACC-3 Trial Conducted by the EORTC Gastrointestinal Group.
Cristina V., Mahachie J., Mauer M., Buclin T., Van Cutsem E., Roth A., Wagner A.D., 2018/07/01. JAMA oncology, 4 (7) pp. 1003-1006. Peer-reviewed.
Stable HIV-1 reservoirs on dolutegravir maintenance monotherapy: the MONODO study.
Sculier D., Doco-Lecompte T., Yerly S., Metzner K.J., Decosterd L.A., Calmy A., 2018/06/22. HIV medicine, 19 (8) pp. 572-577. Peer-reviewed.
 
Fractures vertébrales multiples à l’arrêt du denosumab: comment les éviter? [Multiple Vertebral Fractures after Denosumab Discontinuation: How to Avoid Them?]
Lamy O., Gonzalez Rodriguez E., Stoll D., Aubry-Rozier B., Livio F., 2018/06. Praxis, 107 (12) pp. 649-654. Peer-reviewed.
 
The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction.
Khan A.I., Kapoor A., Chen J., Martin L., Rogazzo M., Mercier T., Decosterd L., Collino M., Thiemermann C., 2018/06. Shock, 49 (6) pp. 675-681. Peer-reviewed.
 
Zika virus, vaccines, and antiviral strategies.
Masmejan S., Baud D., Musso D., Panchaud A., 2018/06. Expert review of anti-infective therapy, 16 (6) pp. 471-483. Peer-reviewed.
 
LC-MS/MS method for the simultaneous analysis of seven antimalarials and two active metabolites in dried blood spots for applications in field trials: Analytical and clinical validation.
Gallay J., Prod'hom S., Mercier T., Bardinet C., Spaggiari D., Pothin E., Buclin T., Genton B., Decosterd L.A., 2018/05/30. Journal of pharmaceutical and biomedical analysis, 154 pp. 263-277. Peer-reviewed.
Appropriateness of malaria diagnosis and treatment for fever episodes according to patient history and anti-malarial blood measurement: a cross-sectional survey from Tanzania.
Gallay J., Mosha D., Lutahakana E., Mazuguni F., Zuakulu M., Decosterd L.A., Genton B., Pothin E., 2018/05/21. Malaria journal, 17 (1) p. 209. Peer-reviewed.
Highlights of the 2017 European AIDS Clinical Society (EACS) Guidelines for the treatment of adult HIV-positive persons version 9.0
Ryom L., Boesecke C., Bracchi M., Ambrosioni J., Pozniak A., Arribas J., Behrens G., Mallon P., Puoti M., Rauch A. et al., 2018/05. HIV Med, 19 (5) pp. 309-315. Peer-reviewed.
 
Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term Performance
Choong E., Uppugunduri C., Marino D., Kuntzinger M., Doffey Lazeyras F., Lo Piccolo R., Chalandon Y., Daali Y., Ansari M., 2018/05. dans 11ème Journée de la recherche clinique 2018, Hôpitaux Universitaires de Genève, Genève.
 
Quantification of the next-generation oral anti-tumor drugs dabrafenib, trametinib, vemurafenib, cobimetinib, pazopanib, regorafenib and two metabolites in human plasma by liquid chromatography-tandem mass spectrometry.
Cardoso E., Mercier T., Wagner A.D., Homicsko K., Michielin O., Ellefsen-Lavoie K., Cagnon L., Diezi M., Buclin T., Widmer N. et al., 2018/04/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1083 pp. 124-136. Peer-reviewed.
Cellular effects of AP102, a somatostatin analog with balanced affinities for the hSSTR2 and hSSTR5 receptors.
Streuli J., Harris A.G., Cottiny C., Allagnat F., Daly A.F., Grouzmann E., Abid K., 2018/04. Neuropeptides, 68 pp. 84-89. Peer-reviewed.
 
Infant Exposure to Methylphenidate and Duloxetine During Lactation.
Collin-Lévesque L., El-Ghaddaf Y., Genest M., Jutras M., Leclair G., Weisskopf E., Panchaud A., Ferreira E., 2018/04. Breastfeeding medicine, 13 (3) pp. 221-225. Peer-reviewed.
 
Pregnancy outcomes in women on metformin for diabetes or other indications among those seeking teratology information services.
Panchaud A., Rousson V., Vial T., Bernard N., Baud D., Amar E., De Santis M., Pistelli A., Dautriche A., Beau-Salinas F. et al., 2018/03. British journal of clinical pharmacology, 84 (3) pp. 568-578. Peer-reviewed.
N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis.
Conus P., Seidman L.J., Fournier M., Xin L., Cleusix M., Baumann P.S., Ferrari C., Cousins A., Alameda L., Gholam-Rezaee M. et al., 2018/02/15. Schizophrenia bulletin, 44 (2) pp. 317-327. Peer-reviewed.
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
 
Pharmacovigilance [Pharmacovigilance update]
Livio F., 2018/01/10. Revue medicale suisse, 14 (588-589) pp. 81-84. Peer-reviewed.
<i>In vitro</i> study of new combinations for local antibiotic therapy with calcium sulphate - Near constant release of ceftriaxone offers new treatment options.
Wahl P., Rönn K., Bohner M., Decosterd L.A., Meier C., Schläppi M., Festa S., Gautier E., 2018. Journal of bone and joint infection, 3 (4) pp. 212-221. Peer-reviewed.
 
Arrêt cardiaque suite à l’administration accidentelle d’amphotéricine B sous forme désoxycholate
Cuda Loredana, Mury Caroline, Pagani Jean-Luc, Revelly Jean-Pierre, Livio Françoise, Aubert John-David, Schaller Marie-Denise, Voirol Pierre, Eggimann Philippe, Que Yok-Ai, 2018. Forum Medical Suisse, 18 (50) pp. 1067-1071. Peer-reviewed.
 
HIV and Aging - Perhaps Not as Dramatic as We Feared?
Engel T., Raffenberg M., Marzolini C., Cavassini M., Kovari H., Hasse B., Tarr P.E., 2018. Gerontology, 64 (5) pp. 446-456. Peer-reviewed.
Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An <i>in Vivo</i> Study With an Experimental Model of Foreign-Body Infection.
Ruppen C., Mercier T., Grandgirard D., Leib S.L., El Haj C., Murillo O., Decosterd L., Sendi P., 2018. Frontiers in microbiology, 9 p. 919. Peer-reviewed.
 
Methods for Personalised Delivery Rate Computation for Propofol IV Administered Anesthetic
Simalatsar Alena, Guidi Monia, Roduit Pierre, Buclin Thierry, 2018. dans Automated Reasoning for System Biology and Medicine, Springer International Publishing.
Predictors of residual antimalarial drugs in the blood in community surveys in Tanzania.
Gallay J., Pothin E., Mosha D., Lutahakana E., Mazuguni F., Zuakulu M., Decosterd L.A., Genton B., 2018. PloS one, 13 (9) pp. e0202745. Peer-reviewed.
 
Prescribing issues in the Swiss HIV infected ageing population
Livio F., Rrustemi F., Moffa G., Elzi L., Stader F., Braun D., Calmy A., Hachfeld A., Cavassini M., Tarr P. et al., 2018., 18th International Society of Pharmacovigilance (ISoP) Annual Meeting, Geneva pp. 1252-1253 dans Drug Safety.
Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale.
Lupattelli A., Twigg M.J., Zagorodnikova K., Moretti M.E., Drozd M., Panchaud A., Rieutord A., Juraski R.G., Odalovic M., Kennedy D. et al., 2018. Clinical epidemiology, 10 pp. 655-669. Peer-reviewed.
 
Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study in 12 European countries using the Edinburgh Postnatal Depression Scale" has been accepted for publication in "Clinical Epidemiology
Lupattelli A., Twigg M.J., Zagorodnikova K., Moretti M.E., Drozd M., Panchaud A., Rieutord R., Gjergja Juraski R., Odalovic M., Kennedy D. et al., 2018. Clinical Epidemiology pp. xx. Peer-reviewed.
Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
Gayi E., Neff L.A., Massana Muñoz X., Ismail H.M., Sierra M., Mercier T., Décosterd L.A., Laporte J., Cowling B.S., Dorchies O.M. et al., 2018. Nature Communications, 9 (1) p. 4848. Peer-reviewed.
 
TDM of cancer therapy: An emerging field
Widmer N., 2018., German Congress of Laboratory Medicine: 15th Annual Congress of the DGKL (German Society of Clinical Chemistry and Laboratory Medicine) and the 3rd Symposium on Biomedical Analysis pp. eA11 dans Journal of Laboratory Medicine.
 
Trabecular bone score (TBS) is associated with sub-clinical vertebral fractures in HIV-infected patients.
Ciullini L., Pennica A., Argento G., Novarini D., Teti E., Pugliese G., Aceti A., Conti F.G., 2018/01. Journal of bone and mineral metabolism, 36 (1) pp. 111-118. Peer-reviewed.
 
Free and total plasma concentrations of elvitegravir/cobicistat during pregnancy and postpartum: a case report.
Marzolini C., Decosterd L., Winterfeld U., Tissot F., Francini K., Buclin T., Livio F., 2017/12. British journal of clinical pharmacology, 83 (12) pp. 2835-2838. Peer-reviewed.
 
OATP1B1 and DAA treatment for hepatitis C in patients with hepatocellular carcinoma.
Chtioui H., 2017/12. Hepatology, 66 (6) p. 2091. Peer-reviewed.
Health care provider communication training in rural Tanzania empowers HIV-infected patients on antiretroviral therapy to discuss adherence problems
Erb S., Letang E., Glass T. R., Natamatungiro A., Mnzava D., Mapesi H., Haschke M., Duthaler U., Berger B., Muri L. et al., 2017/10. HIV Med, 18 (9) pp. 623-634. Peer-reviewed.
Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps.
Arensdorff L., Boillat-Blanco N., Decosterd L., Buclin T., de Vallière S., 2017/09/01. The Journal of antimicrobial chemotherapy, 72 (9) pp. 2613-2615. Peer-reviewed.
 
Darunavir concentrations in CSF of HIV-infected individuals when boosted with cobicistat versus ritonavir.
Bartels H., Decosterd L., Battegay M., Marzolini C., 2017/09/01. The Journal of antimicrobial chemotherapy, 72 (9) pp. 2574-2577. Peer-reviewed.
 
Drug-induced hemolytic anemia: Pharmacological aspects.
Renard D., Rosselet A., 2017/09. Transfusion clinique et biologique, 24 (3) pp. 110-114. Peer-reviewed.
 
Lamotrigine serum levels: Ceiling effect in people with epilepsy in remission?
D'Anto J., Wnuk W., Rossetti A.O., Decosterd L.A., Buclin T., Novy J., 2017/09. Epilepsy & behavior, 74 pp. 41-44. Peer-reviewed.
 
Renal Drug Transporters and Drug Interactions.
Ivanyuk A., Livio F., Biollaz J., Buclin T., 2017/08. Clinical pharmacokinetics, 56 (8) pp. 825-892. Peer-reviewed.
 
Guidance to develop individual dose recommendations for patients on chronic hemodialysis.
Gotta V., Dao K., Rodieux F., Buclin T., Livio F., Pfister M., 2017/07. Expert review of clinical pharmacology, 10 (7) pp. 737-752. Peer-reviewed.
 
Simultaneous determination of selective serotonin reuptake inhibitors and their main metabolites in human breast milk by liquid chromatography-electrospray mass spectrometry.
Weisskopf E., Panchaud A., Nguyen K.A., Grosjean D., Hascoët J.M., Csajka C., Eap C.B., Ansermot N., collaborators of the SSRI-Breast Milk study, 2017/07/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1057 pp. 101-109. Peer-reviewed.
 
Nonparametric estimation of pregnancy outcome probabilities
Friedrich Sarah, Beyersmann Jan, Winterfeld Ursula, Schumacher Martin, Allignol Arthur, 2017/06/01. The Annals of Applied Statistics, 11 (2).
 
Prevalence of polypharmacy in the Swiss HIV Cohort Study (SHCS). Le futur c’est maintenant !
Courlet P., Cavassini M., Choong E., Csajka C., Marzolini C., Decosterd L., and the Swiss HIV Cohort Study, 2017/05/03. dans SSMIG SSPTC Spring Meeting, Lausanne EPFL.
Antibiotic stability related to temperature variations in elastomeric pumps used for outpatient parenteral antimicrobial therapy (OPAT).
Voumard R., Van Neyghem N., Cochet C., Gardiol C., Decosterd L., Buclin T., de Valliere S., 2017/05/01. The Journal of antimicrobial chemotherapy, 72 (5) pp. 1462-1465. Peer-reviewed.
 
N-acetyl-cysteine in a double-blind randomized placebo-controlled trial: Towards biomarker guided treatment in early psychosis
Conus P., Fournier M., Xin L., Baumann P., Ferrari C., Cousins A., Alameda L., Golay P., Jenni R., Kashavan M.S. et al., 2017/04. pp. S806 dans European Psychiatry, Elsevier BV.
 
Pharmacokinetics of Pomalidomide in a Patient Receiving Hemodialysis Using a High-Cutoff Filter.
Dao K., Chtioui H., Lu Y., Peer C.J., Figg W.D., Pruijm M., Buclin T., Kissling S., 2017/04. American journal of kidney diseases, 69 (4) pp. 553-554. Peer-reviewed.
 
Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes
Marzolini C., Rajoli R., Battegay M., Elzi L., Back D., Siccardi M., 2017/04. Clin Pharmacokinet, 56 (4) pp. 409-420. Peer-reviewed.
 
Population Pharmacokinetics and Pharmacogenetics Analysis of Rilpivirine in HIV-1-Infected Individuals.
Aouri M., Barcelo C., Guidi M., Rotger M., Cavassini M., Hizrel C., Buclin T., Decosterd L.A., Csajka C., Swiss HIV Cohort Study, 2017/04. Antimicrobial agents and chemotherapy, 61 (1) p. 10. Peer-reviewed.
 
Recurrent Asystole After Neostigmine in a Heart Transplant Recipient With End-Stage Renal Disease.
Cachemaille M., Olofsson M., Livio F., Pascale P., Zingg T., Boegli Y., 2017/04. Journal of cardiothoracic and vascular anesthesia, 31 (2) pp. 653-656. Peer-reviewed.
 
SA19. N-Acetyl-Cysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
Do Kim, Seidman Larry J., Fournier Margot, Xin Lijing, Cleusix Martine, Baumann Philipp S., Ferrari Carina, Cousins Ann, Alameda Luis, Gholam-Rezaee Mehdi et al., 2017/03/01. pp. S119-S120 dans Schizophrenia Bulletin, Oxford University Press (OUP).
 
Therapeutic Drug Monitoring in CML treatment - Experience from two reference centers
Choong E., Decosterd L., 2017/01/20. dans European Ponatinib Plasma Testing Workshop, Incyte, Lausanne, Switzerland .
 
Adverse drug reactions as a cause of admission to intensive care unit: a 4-months prospective cohort study
Berthaut V., Renard D., Schaller M.D., Manzon C., Voirol P., Buclin T., Livio F., 2017., 17th International Society of Pharmacovigilance (ISoP) Annual Meeting, Liverpool p. 944 dans Drug Safety.
 
Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies
Bondallaz P., Chtioui H., Favrat B., Fornari E., Giroud C., Maeder P., 2017. pp. 379-390 dans Handbook of Cannabis and Related Pathologies chap. 39, Elsevier BV.
Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection
Seden K., Gibbons S., Marzolini C., Schapiro J. M., Burger D. M., Back D. J., Khoo S. H., 2017. PLoS One, 12 (3) pp. e0173509. Peer-reviewed.
 
Direct oral anticoagulants: are they safer than vitamin K antagonists?
Baumberger M., Hugli O., Buclin T., Livio F., 2017., 17th International Society of Pharmacovigilance (ISoP) Annual Meeting, Liverpool pp. 943-944 dans Drug Safety.
 
Dolutegravir plasma levels after gastric bypass surgery
Piso R. J., Battegay M., Marzolini C., 2017. AIDS, 31 (7) pp. 1052-1054. Peer-reviewed.
Intravenous lacosamide in status epilepticus: Correlation between loading dose, serum levels, and clinical response.
Perrenoud M., André P., Alvarez V., Stähli C., Decosterd L.A., Rossetti A.O., Novy J., 2017. Epilepsy Research, 135 pp. 38-42. Peer-reviewed.
 
Pharmacokinetics of lenalidomide during high cut-off dialysis in a patient with multiple myeloma and renal failure.
Dao K., Lu Y., Peer C.J., Figg W.D., Stadelmann R., Burnier M., Buclin T., Kissling S., 2017/01. Cancer chemotherapy and pharmacology, 79 (1) pp. 215-218. Peer-reviewed.
 
The levels of vancomycin in the blood and the wound after the local treatment of bone and soft-tissue infection with antibiotic-loaded calcium sulphate as carrier material.
Wahl P., Guidi M., Benninger E., Rönn K., Gautier E., Buclin T., Magnin J.L., Livio F., 2017. The Bone & Joint Journal, 99-B (11) pp. 1537-1544. Peer-reviewed.
 
Use of Dipeptidyl-Peptidase IV Inhibitors and Bullous Pemphigoid.
Schaffer C., Buclin T., Jornayvaz F.R., Cazzaniga S., Borradori L., Gilliet M., Feldmeyer L., 2017. Dermatology, 233 (5) pp. 401-403. Peer-reviewed.
Population Genetic-Based Pharmacokinetic Modeling of Methadone and its Relationship with the QTc Interval in Opioid-Dependent Patients.
Csajka C., Crettol S., Guidi M., Eap C.B., 2016/12. Clinical pharmacokinetics, 55 (12) pp. 1521-1533. Peer-reviewed.
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