Department of Fundamental Oncology

Publications | Phd and Masters theses

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659 publications

... | 2020 | 2019 | 2018 | 2017 | ...
2020
Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells.
Martinez-Usatorre A., Carmona S.J., Godfroid C., Yacoub Maroun C., Labiano S., Romero P., 2020. Frontiers in immunology, 11 p. 340. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8D693EC9FE6D]
 
Generation of affinity ranged antigen-expressing tumor cell lines.
Martinez-Usatorre A., Romero P., 2020. Methods in enzymology, 632 pp. 503-519. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F109492FE826]
 
High-throughput identification of human antigen-specific CD8<sup>+</sup> and CD4<sup>+</sup> T cells using soluble pMHC multimers.
Magnin M., Guillaume P., Coukos G., Harari A., Schmidt J., 2020. Methods in enzymology, 631 pp. 21-42. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FD66E29F7790]
 
Immunity, Hypoxia, and Metabolism-the Ménage à Trois of Cancer: Implications for Immunotherapy.
Riera-Domingo C., Audigé A., Granja S., Cheng W.C., Ho P.C., Baltazar F., Stockmann C., Mazzone M., 2020/01/01. Physiological reviews, 100 (1) pp. 1-102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6448AD630AF8]
LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures.
Gestermann N., Saugy D., Martignier C., Tillé L., Fuertes Marraco S.A., Zettl M., Tirapu I., Speiser D.E., Verdeil G., 2020. Oncoimmunology, 9 (1) p. 1736792. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FD23668D4829]
Moving cancer immunotherapy forward through the Journal for ImmunoTherapy of Cancer (JITC).
Romero P., 2020/01. Journal for immunotherapy of cancer, 8 (1) pp. :e000001. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FCC3B078539C]
Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal.
Bianchi V., Harari A., Coukos G., 2020. Frontiers in immunology, 11 p. 1215. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B0551F2A3933]
 
Novel Strategies of Anti-Tumor Vaccines
Bassani Sternberg Michal, 2020., Frontiers Media SA.
[DOI][serval:BIB_B78B3712DBD3]
 
Recombinant fusion proteins for targeting dendritic cell subsets in therapeutic cancer vaccine.
Corgnac S., Botelho N.K., Donda A., Romero P., 2020. Methods in enzymology, 632 pp. 521-543. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67289CA04690]
Virus-like particles for vaccination against cancer.
Mohsen M.O., Speiser D.E., Knuth A., Bachmann M.F., 2020/01. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 12 (1) pp. e1579. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FA959DAE62AF]
2019
 
Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry.
Girotra M., Thierry A.C., Harari A., Coukos G., Naveiras O., Vannini N., 2019/12/26. Journal of visualized experiments 154. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DE9A27B5B4E4]
Microfluidic device performing on flow study of serial cell-cell interactions of two cell populations.
Duchamp M., Dahoun T., Vaillier C., Arnaud M., Bobisse S., Coukos G., Harari A., Renaud P., 2019/12/09. RSC advances, 9 (70) pp. 41066-41073. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2E280C4A083E]
 
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8<sup>+</sup> T-cell Responses.
Liu Y., Cuendet M.A., Goffin L., Šachl R., Cebecauer M., Cariolato L., Guillaume P., Reichenbach P., Irving M., Coukos G. et al., 2019/12/06. Journal of molecular biology, 431 (24) pp. 4941-4958. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7D824F910BFC]
 
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis.
Dafni U., Michielin O., Lluesma S.M., Tsourti Z., Polydoropoulou V., Karlis D., Besser M.J., Haanen J., Svane I.M., Ohashi P.S. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1902-1913. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DF9E566FB280]
Enhancement of Antiviral CD8+ T-Cell Responses and Complete Remission of Metastatic Melanoma in an HIV-1-Infected Subject Treated with Pembrolizumab.
Blanch-Lombarte O., Gálvez C., Revollo B., Jiménez-Moyano E., Llibre J.M., Manzano J.L., Boada A., Dalmau J., Speiser D.E., Clotet B. et al., 2019/12/01. Journal of clinical medicine, 8 (12). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F7B5C0ED21BA]
 
Gender medicine and oncology: report and consensus of an ESMO workshop.
Wagner A.D., Oertelt-Prigione S., Adjei A., Buclin T., Cristina V., Csajka C., Coukos G., Dafni U., Dotto G.P., Ducreux M. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1914-1924. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C7C76EA90383]
Herpes simplex encephalitis in adult patients with MASP-2 deficiency.
Bibert S., Piret J., Quinodoz M., Collinet E., Zoete V., Michielin O., Menasria R., Meylan P., Bihl T., Erard V. et al., 2019/12. PLoS pathogens, 15 (12) pp. e1008168. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_568322E0BDD0]
Systemic and central nervous system metabolic alterations in Alzheimer's disease
van der Velpen Vera, Teav Tony, Gallart-Ayala Héctor, Mehl Florence, Konz Ioana, Clark Christopher, Oikonomidi Aikaterini, Peyratout Gwendoline, Henry Hugues, Delorenzi Mauro et al., 2019/12. Alzheimer's Research & Therapy, 11 (1). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_901648E242CF]
 
The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies.
Jandus P., Boligan K.F., Smith D.F., de Graauw E., Grimbacher B., Jandus C., Abdelhafez M.M., Despont A., Bovin N., Simon D. et al., 2019/11/28. Blood, 134 (22) pp. 1941-1950. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_81D29BA86AAD]
 
Evaluating Magnetic Resonance Spectroscopy as a Tool for Monitoring Therapeutic Response of Whole Brain Radiotherapy in a Mouse Model for Breast-to-Brain Metastasis.
Chae W.H., Niesel K., Schulz M., Klemm F., Joyce J.A., Prümmer M., Brill B., Bergs J., Rödel F., Pilatus U. et al., 2019/11/27. Frontiers in oncology, 9 p. 1324. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_22B16FC3657F]
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma.
Sarivalasis A., Boudousquié C., Balint K., Stevenson B.J., Gannon P.O., Iancu E.M., Rossier L., Martin Lluesma S., Mathevet P., Sempoux C. et al., 2019/11/26. Journal of translational medicine, 17 (1) p. 391. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_313F7CD9FDBC]
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.
Salomé B., Gomez-Cadena A., Loyon R., Suffiotti M., Salvestrini V., Wyss T., Vanoni G., Ruan D.F., Rossi M., Tozzo A. et al., 2019/11/26. Blood advances, 3 (22) pp. 3674-3687. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BC26C680B22]
Towards Quantification of Inflammation in Atherosclerotic Plaque in the Clinic - Characterization and Optimization of Fluorine-19 MRI in Mice at 3 T.
Darçot E., Colotti R., Pellegrin M., Wilson A., Siegert S., Bouzourene K., Yerly J., Mazzolai L., Stuber M., van Heeswijk R.B., 2019/11/25. Scientific reports, 9 (1) p. 17488. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_40394E9CBB35]
Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy.
Verdeil G., Lawrence T., Schmitt-Verhulst A.M., Auphan-Anezin N., 2019/11/21. Cancers, 11 (12). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_34CE8413C2A8]
Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma.
Tsantoulis P., Delorenzi M., Bièche I., Vacher S., Mariani P., Cassoux N., Houy A., Stern M.H., Roman-Roman S., Dietrich P.Y. et al., 2019/11/20. Scientific reports, 9 (1) p. 17178. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B2ADA6C4E5AE]
Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment.
Newey A., Griffiths B., Michaux J., Pak H.S., Stevenson B.J., Woolston A., Semiannikova M., Spain G., Barber L.J., Matthews N. et al., 2019/11/18. Journal for immunotherapy of cancer, 7 (1) p. 309. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7418AE3DFDA7]
Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes.
Duong M.N., Erdes E., Hebeisen M., Rufer N., 2019/11/05. Journal for immunotherapy of cancer, 7 (1) p. 284. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F1677E168BF3]
Defining 'T cell exhaustion'.
Blank C.U., Haining W.N., Held W., Hogan P.G., Kallies A., Lugli E., Lynn R.C., Philip M., Rao A., Restifo N.P. et al., 2019/11. Nature reviews. Immunology, 19 (11) pp. 665-674. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_46B67C7C36BE]
 
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.
Racle J., Michaux J., Rockinger G.A., Arnaud M., Bobisse S., Chong C., Guillaume P., Coukos G., Harari A., Jandus C. et al., 2019/11. Nature biotechnology, 37 (11) pp. 1283-1286. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D9A8D08A5BC6]
Intratumoral CD8<sup>+</sup> T cells with stem cell-like properties: Implications for cancer immunotherapy.
Held W., Siddiqui I., Schaeuble K., Speiser D.E., 2019/10/23. Science translational medicine, 11 (515) pp. eaay6863. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_2890415E8A72]
 
The Romand Network of Oncology: bridging the gap of personalised oncology
Michielin O., Tsantoulis P., Homicsko K., Christinat Y., De Leval L., Bisig B., Missiaglia E., Zoete V., Krebs F., Fortin A. et al., 2019/10/18. Swiss Medical Weekly.
[serval:BIB_2A3947B3BCE2]
 
CDK4 Regulates Lysosomal Function and mTORC1 Activation to Promote Cancer Cell Survival.
Martínez-Carreres L., Puyal J., Leal-Esteban L.C., Orpinell M., Castillo-Armengol J., Giralt A., Dergai O., Moret C., Barquissau V., Nasrallah A. et al., 2019/10/15. Cancer research, 79 (20) pp. 5245-5259. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A55F9416C381]
 
Tape-Stripping Electrochemical Detection of Melanoma.
Darvishi S., Pick H., Lin T.E., Zhu Y., Li X., Ho P.C., Girault H.H., Lesch A., 2019/10/15. Analytical chemistry, 91 (20) pp. 12900-12908. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4B5AE89097F4]
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8<sup>+</sup> T cells.
Mastelic-Gavillet B., Navarro Rodrigo B., Décombaz L., Wang H., Ercolano G., Ahmed R., Lozano L.E., Ianaro A., Derré L., Valerio M. et al., 2019/10/10. Journal for immunotherapy of cancer, 7 (1) p. 257. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CC3C085DEA43]
 
Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Röhrig U.F., Reynaud A., Majjigapu S.R., Vogel P., Pojer F., Zoete V., 2019/10/10. Journal of medicinal chemistry, 62 (19) pp. 8784-8795. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D8CCFFB94292]
 
Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis.
Duc D., Vigne S., Bernier-Latmani J., Yersin Y., Ruiz F., Gaïa N., Leo S., Lazarevic V., Schrenzel J., Petrova T.V. et al., 2019/10/08. Cell reports, 29 (2) pp. 378-390.e4. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6227A92C8D06]
 
Fifty Shades of α-Ketoglutarate on Cellular Programming.
Di Conza G., Tsai C.H., Ho P.C., 2019/10/03. Molecular cell, 76 (1) pp. 1-3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CB375784E0F9]
 
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Cossarizza A., Chang H.D., Radbruch A., Acs A., Adam D., Adam-Klages S., Agace W.W., Aghaeepour N., Akdis M., Allez M. et al., 2019/10. European journal of immunology, 49 (10) pp. 1457-1973. Peer-reviewed.
[DOI][Pmid][serval:BIB_84601DD1FB58]
Application of the SwissDrugDesign Online Resources in Virtual Screening.
Daina A., Zoete V., 2019/09/18. International journal of molecular sciences, 20 (18) p. 4612. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B934FE45EAA7]
Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery.
Fierle J.K., Abram-Saliba J., Brioschi M., deTiani M., Coukos G., Dunn S.M., 2019/09/06. Scientific reports, 9 (1) p. 12815. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FCB67A02E15F]
Peripheral Innate Lymphoid Cells Are Increased in First Line Metastatic Colorectal Carcinoma Patients: A Negative Correlation With Th1 Immune Responses
Loyon Romain, Jary Marine, Salomé Bérengère, Gomez-Cadena Alejandra, Galaine Jeanne, Kroemer Marie, Romero Pedro, Trabanelli Sara, Adotévi Olivier, Borg Christophe et al., 2019/09/06. Frontiers in Immunology, 10 p. 2121. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_3FC0B4BB29C7]
 
Biomodulina T partially restores immunosenescent CD4 and CD8 T cell compartments in the elderly.
Saavedra D., Fuertes S.A., Suárez G.M., González A., Lorenzo-Luaces P., García B., Aznar E., Mazorra Z., Crombet T., Speiser D.E. et al., 2019/09. Experimental gerontology, 124 p. 110633. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6E061DCF6353]
 
Cancer Immunotherapy: A Simple Guide for Interventional Radiologists of New Therapeutic Approaches.
Digklia A., Duran R., Homicsko K., Kandalaft L.E., Hocquelet A., Orcurto A., Coukos G., Denys A., 2019/09. Cardiovascular and interventional radiology, 42 (9) pp. 1221-1229. Peer-reviewed.
[DOI][Pmid][serval:BIB_13E5E5B29D1D]
 
Firing Up Cold Tumors.
Cheng W.C., Ho P.C., 2019/09. Trends in cancer, 5 (9) pp. 528-530. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F50ED56DE9EB]
 
Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands".
Rolfs Z., Müller M., Shortreed M.R., Smith L.M., Bassani-Sternberg M., 2019/08/16. Science immunology, 4 (38). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0BB6D028A753]
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients
Bassani-Sternberg Michal, Digklia Antonia, Huber Florian, Wagner Dorothea, Sempoux Christine, Stevenson Brian J., Thierry Anne-Christine, Michaux Justine, Pak HuiSong, Racle Julien et al., 2019/08/08. Frontiers in Immunology, 10 p. 1832. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0144F5D289B5]
 
Challenges to curing primary brain tumours.
Aldape K., Brindle K.M., Chesler L., Chopra R., Gajjar A., Gilbert M.R., Gottardo N., Gutmann D.H., Hargrave D., Holland E.C. et al., 2019/08. Nature reviews. Clinical oncology, 16 (8) pp. 509-520. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BAF957625821]
 
F-18-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer.
Jreige M., Letovanec I., Chaba K., Renaud S., Rusakiewicz S., Cristina V., Peters S., Krueger T., de Leval L., Kandalaft L.E. et al., 2019/08. European journal of nuclear medicine and molecular imaging, 46 (9) pp. 1859-1868. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F575C6723CE]
 
Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study.
Khoja L., Atenafu E.G., Suciu S., Leyvraz S., Sato T., Marshall E., Keilholz U., Zimmer L., Patel S.P., Piperno-Neumann S. et al., 2019/08/01. Annals of oncology, 30 (8) pp. 1370-1380. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BD137DAA9150]
Rational combinations of immunotherapy with radiotherapy in ovarian cancer.
Herrera F.G., Irving M., Kandalaft L.E., Coukos G., 2019/08. The Lancet. Oncology, 20 (8) pp. e417-e433. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B919A825548B]
 
Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'.
Aldape K., Brindle K.M., Chesler L., Chopra R., Gajjar A., Gilbert M.R., Gottardo N., Gutmann D.H., Hargrave D., Holland E.C. et al., 2019/08. Nature reviews. Clinical oncology, 16 (8) pp. 522-523. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B957A30B68EB]
 
Sculpting tumor microenvironment with immune system: from immunometabolism to immunoediting.
Yu Y.R., Ho P.C., 2019/08. Clinical and experimental immunology, 197 (2) pp. 153-160. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F2A32ECC9A7]
 
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.
Costa-Nunes C., Cachot A., Bobisse S., Arnaud M., Genolet R., Baumgaertner P., Speiser D.E., Sousa Alves P.M., Sandoval F., Adotévi O. et al., 2019/07/15. Clinical cancer research, 25 (14) pp. 4320-4331. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_99ED3D648751]
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.
Ayeni D., Miller B., Kuhlmann A., Ho P.C., Robles-Oteiza C., Gaefele M., Levy S., de Miguel F.J., Perry C., Guan T. et al., 2019/07/10. Journal for immunotherapy of cancer, 7 (1) p. 172. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_765E95D84B97]
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules.
Daina A., Michielin O., Zoete V., 2019/07/02. Nucleic acids research, 47 (W1) pp. W357-W364. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_37625953AF4B]
 
Association of Checkpoint Inhibitor–Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non–Small Cell Lung Cancer
Berner Fiamma, Bomze David, Diem Stefan, Ali Omar Hasan, Fässler Mirjam, Ring Sandra, Niederer Rebekka, Ackermann Christoph J., Baumgaertner Petra, Pikor Natalia et al., 2019/07/01. JAMA Oncology, 5 (7) p. 1043.
[DOI][WoS][Pmid][serval:BIB_9952A126F24F]
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.
Schaeuble K., Cannelle H., Favre S., Huang H.Y., Oberle S.G., Speiser D.E., Zehn D., Luther S.A., 2019/07. PLoS biology, 17 (7) pp. e3000072. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6C21F8646A14]
 
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy.
Li X., Wenes M., Romero P., Huang S.C., Fendt S.M., Ho P.C., 2019/07. Nature reviews. Clinical oncology, 16 (7) pp. 425-441. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F7C5AE601718]
 
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Alfei F., Kanev K., Hofmann M., Wu M., Ghoneim H.E., Roelli P., Utzschneider D.T., von Hoesslin M., Cullen J.G., Fan Y. et al., 2019/07. Nature, 571 (7764) pp. 265-269. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_00D136C4113F]
 
RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Gbenedio O.M., Bonnans C., Grun D., Wang C.Y., Hatch A.J., Mahoney M.R., Barras D., Matli M., Miao Y., Garcia K.C. et al., 2019/06/25. JCI insight, 5 pp. e127552. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3AFCE6869632]
Mass spectrometry driven exploration reveals nuances of neoepitope-driven tumor rejection.
Ebrahimi-Nik H., Michaux J., Corwin W.L., Keller G.L., Shcheglova T., Pak H., Coukos G., Baker B.M., Mandoiu I.I., Bassani-Sternberg M. et al., 2019/06/20. JCI insight, 5. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_77410C339277]
Internal radiation dosimetry of a <sup>152</sup>Tb-labeled antibody in tumor-bearing mice.
Cicone F., Gnesin S., Denoël T., Stora T., van der Meulen N.P., Müller C., Vermeulen C., Benešová M., Köster U., Johnston K. et al., 2019/06/11. EJNMMI research, 9 (1) p. 53. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_22C26DF26A4B]
Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation.
Lenti E., Bianchessi S., Proulx S.T., Palano M.T., Genovese L., Raccosta L., Spinelli A., Drago D., Andolfo A., Alfano M. et al., 2019/06/11. Stem cell reports, 12 (6) pp. 1260-1268. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_51D0703A660E]
 
Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Dangaj D., Bruand M., Grimm A.J., Ronet C., Barras D., Duttagupta P.A., Lanitis E., Duraiswamy J., Tanyi J.L., Benencia F. et al., 2019/06/10. Cancer cell, 35 (6) pp. 885-900.e10. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_95C8776874F3]
 
Bi-allelic Variants in DYNC1I2 Cause Syndromic Microcephaly with Intellectual Disability, Cerebral Malformations, and Dysmorphic Facial Features.
Ansar M., Ullah F., Paracha S.A., Adams D.J., Lai A., Pais L., Iwaszkiewicz J., Millan F., Sarwar M.T., Agha Z. et al., 2019/06/06. American journal of human genetics, 104 (6) pp. 1073-1087. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_29D795794213]
 
Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis.
Saglietti C., La Rosa S., Sykiotis G.P., Letovanec I., Bulliard J.L., Piana S., Mermod M., Petrova T., Uccella S., Sessa F. et al., 2019/06. Endocrine pathology, 30 (2) pp. 138-145. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_564B70BCE78F]
 
MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma.
Martinez-Usatorre A., Sempere L.F., Carmona S.J., Carretero-Iglesia L., Monnot G., Speiser D.E., Rufer N., Donda A., Zehn D., Jandus C. et al., 2019/06. Cancer immunology research, 7 (6) pp. 1013-1024. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4CB1877985DB]
Re-education of macrophages as a therapeutic strategy in cancer.
Kowal J., Kornete M., Joyce J.A., 2019/06. Immunotherapy, 11 (8) pp. 677-689. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7E2B9DDA760A]
 
Correction to: Vaccination with nanoparticles combined with micro-adjuvants protects against cancer.
Mohsen M.O., Heath M.D., Cabral-Miranda G., Lipp C., Zeltins A., Sande M., Stein J.V., Riether C., Roesti E., Zha L. et al., 2019/05/23..
[DOI][WoS][Pmid][serval:BIB_F6CF25B028EC]
 
Tumor Landscapes: β-Catenin Drives Immune Desertification.
Dangaj D., Barras D., Coukos G., 2019/05/15. Clinical cancer research, 25 (10) pp. 2943-2945. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7529A1E77088]
Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients.
Broggi MAS, Maillat L., Clement C.C., Bordry N., Corthésy P., Auger A., Matter M., Hamelin R., Potin L., Demurtas D. et al., 2019/05/06. The Journal of experimental medicine, 216 (5) pp. 1091-1107. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_83C31BFEAA5C]
 
Siglec-9 Regulates an Effector Memory CD8<sup>+</sup> T-cell Subset That Congregates in the Melanoma Tumor Microenvironment.
Haas Q., Boligan K.F., Jandus C., Schneider C., Simillion C., Stanczak M.A., Haubitz M., Seyed Jafari S.M., Zippelius A., Baerlocher G.M. et al., 2019/05. Cancer immunology research, 7 (5) pp. 707-718. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AA99A510B25F]
Vaccination with nanoparticles combined with micro-adjuvants protects against cancer.
Mohsen M.O., Heath M.D., Cabral-Miranda G., Lipp C., Zeltins A., Sande M., Stein J.V., Riether C., Roesti E., Zha L. et al., 2019/04/26. Journal for immunotherapy of cancer, 7 (1) p. 114. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_D5AD3DB36450]
The clinical application of cancer immunotherapy based on naturally circulating dendritic cells.
Bol K.F., Schreibelt G., Rabold K., Wculek S.K., Schwarze J.K., Dzionek A., Teijeira A., Kandalaft L.E., Romero P., Coukos G. et al., 2019/04/18. Journal for immunotherapy of cancer, 7 (1) p. 109. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5E54765B4162]
Maf deficiency in T cells dysregulates T<sub>reg</sub> - T<sub>H</sub>17 balance leading to spontaneous colitis.
Imbratta C., Leblond M.M., Bouzourène H., Speiser D.E., Velin D., Verdeil G., 2019/04/16. Scientific reports, 9 (1) p. 6135. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B94E063539E7]
γ-Catenin-Dependent Signals Maintain BCR-ABL1<sup>+</sup> B Cell Acute Lymphoblastic Leukemia.
Luong-Gardiol N., Siddiqui I., Pizzitola I., Jeevan-Raj B., Charmoy M., Huang Y., Irmisch A., Curtet S., Angelov G.S., Danilo M. et al., 2019/04/15. Cancer cell, 35 (4) pp. 649-663.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B56A0F7637FF]
 
Correction: Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Westergaard MCW, Andersen R., Chong C., Kjeldsen J.W., Pedersen M., Friese C., Hasselager T., Lajer H., Coukos G., Bassani-Sternberg M. et al., 2019/04..
[DOI][WoS][Pmid][serval:BIB_5C827EDF3F51]
 
Going Beyond the Sequences: TCR Binding Patterns at the Service of Cancer Detection.
Zoete V., Coukos G., 2019/04/01. Cancer research, 79 (7) pp. 1299-1301. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B6A2460E1FCA]
 
Publisher Correction: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/04..
[DOI][WoS][Pmid][serval:BIB_2453C5C48240]
Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer.
Lan Q., Peyvandi S., Duffey N., Huang Y.T., Barras D., Held W., Richard F., Delorenzi M., Sotiriou C., Desmedt C. et al., 2019/04. Oncogene, 38 (15) pp. 2814-2829. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_94A8CCA9EF90]
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret C., Miah SMS, Rota G., Fonta N.P., Wang H., Held W., Birchmeier W., Sexl V., Yang W., Vivier E. et al., 2019/03/29. Nature communications, 10 (1) p. 1444. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1D70F1981844]
 
Biallelic variants in FBXL3 cause intellectual disability, delayed motor development and short stature.
Ansar M., Paracha S.A., Serretti A., Sarwar M.T., Khan J., Ranza E., Falconnet E., Iwaszkiewicz J., Shah S.F., Qaisar A.A. et al., 2019/03/15. Human molecular genetics, 28 (6) pp. 972-979. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CC3DB25E32E9]
Circulating CD56<sup>bright</sup> NK cells inversely correlate with survival of melanoma patients.
de Jonge K., Ebering A., Nassiri S., Maby-El Hajjami H., Ouertatani-Sakouhi H., Baumgaertner P., Speiser D.E., 2019/03/14. Scientific reports, 9 (1) p. 4487. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_07410EEFFC5B]
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Vannini N., Campos V., Girotra M., Trachsel V., Rojas-Sutterlin S., Tratwal J., Ragusa S., Stefanidis E., Ryu D., Rainer P.Y. et al., 2019/03/07. Cell stem cell, 24 (3) pp. 405-418.e7. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9C9755E6E69D]
CD73 expression in normal and pathological human hepatobiliopancreatic tissues.
Sciarra A., Monteiro I., Ménétrier-Caux C., Caux C., Gilbert B., Halkic N., La Rosa S., Romero P., Sempoux C., de Leval L., 2019/03. Cancer immunology, immunotherapy, 68 (3) pp. 467-478. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_97044E671671]
 
Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Sciarra Amedeo, Monteiro Inês, Ménétrier-Caux Christine, Caux Christophe, Gilbert Benoit, Halkic Nermin, La Rosa Stefano, Romero Pedro, Sempoux Christine, de Leval Laurence, 2019/03. 1.
[DOI][WoS][Pmid][serval:BIB_7C8F554D8B37]
Differential regulation of RNA polymerase III genes during liver regeneration.
Yeganeh M., Praz V., Carmeli C., Villeneuve D., Rib L., Guex N., Herr W., Delorenzi M., Hernandez N., CycliX consortium, 2019/02/28. Nucleic Acids Research, 47 (4) pp. 1786-1796. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_014840C5C9E3]
Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides.
Bargeton B., Iwaszkiewicz J., Bonifacio G., Roy S., Zoete V., Kellenberger S., 2019/02/22. Scientific reports, 9 (1) p. 2599. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3C115A0AD37A]
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.
Guay C., Kruit J.K., Rome S., Menoud V., Mulder N.L., Jurdzinski A., Mancarella F., Sebastiani G., Donda A., Gonzalez B.J. et al., 2019/02/05. Cell metabolism, 29 (2) pp. 348-361.e6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_32A6AD8B1141]
50-Gy Stereotactic Body Radiation Therapy to the Dominant Intraprostatic Nodule: Results From a Phase 1a/b Trial.
Herrera F.G., Valerio M., Berthold D., Tawadros T., Meuwly J.Y., Vallet V., Baumgartner P., Thierry A.C., De Bari B., Jichlinski P. et al., 2019/02/01. International journal of radiation oncology, biology, physics, 103 (2) pp. 320-334. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8A5A6B3310C5]
NK cells specifically TCR-dressed to kill cancer cells.
Mensali N., Dillard P., Hebeisen M., Lorenz S., Theodossiou T., Myhre M.R., Fåne A., Gaudernack G., Kvalheim G., Myklebust J.H. et al., 2019/02. EBioMedicine, 40 pp. 106-117. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C96D4A7DAD14]
 
Prediction of Occult Lymph Node Metastasis in Head and Neck Cancer with CD31 Vessel Quantification.
Mermod M., Bongiovanni M., Petrova T., Goun E., Simon C., Tolstonog G., Monnier Y., 2019/02. Otolaryngology: head and neck surgery, 160 (2) pp. 277-283. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9BFA9A270953]
Safety and Tolerability of Adoptive Cell Therapy in Cancer.
Wolf B., Zimmermann S., Arber C., Irving M., Trueb L., Coukos G., 2019/02. Drug safety, 42 (2) pp. 315-334. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_944ED4AF4291]
 
The pro- and anti-tumor role of ILC2s.
Trabanelli S., Chevalier M.F., Derré L., Jandus C., 2019/02. Seminars in immunology, 41 p. 101276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_ECAD6DCB8107]
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Westergaard MCW, Andersen R., Chong C., Kjeldsen J.W., Pedersen M., Friese C., Hasselager T., Lajer H., Coukos G., Bassani-Sternberg M. et al., 2019/02. British journal of cancer, 120 (4) pp. 424-434. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_031BC21D26AB]
 
Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/02. Nature immunology, 20 (2) pp. 206-217. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A10BFBC01F0D]
Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Hendrikx S., Coso S., Prat-Luri B., Wetterwald L., Sabine A., Franco C.A., Nassiri S., Zangger N., Gerhardt H., Delorenzi M. et al., 2019/01/29. Cell reports, 26 (5) pp. 1227-1241.e6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B316C6C93CB8]
Imaging endogenous macrophage iron deposits reveals a metabolic biomarker of polarized tumor macrophage infiltration and response to CSF1R breast cancer immunotherapy.
Leftin A., Ben-Chetrit N., Joyce J.A., Koutcher J.A., 2019/01/29. Scientific reports, 9 (1) p. 857. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_60BF21E76912]
 
Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.
Ben-David M., Huang H., Sun MGF, Corbi-Verge C., Petsalaki E., Liu K., Gfeller D., Garg P., Tempel W., Sochirca I. et al., 2019/01/18. Journal of molecular biology, 431 (2) pp. 336-350. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A87AEE8073C3]
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I., Schaeuble K., Chennupati V., Fuertes Marraco S.A., Calderon-Copete S., Pais Ferreira D., Carmona S.J., Scarpellino L., Gfeller D., Pradervand S. et al., 2019/01/15. Immunity, 50 (1) pp. 195-211.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8DBCBF3E53B5]
A structural model of the immune checkpoint CD160-HVEM complex derived from HDX-mass spectrometry and molecular modeling.
Kuncewicz K., Spodzieja M., Sieradzan A., Karczyńska A., Dąbrowska K., Dadlez M., Speiser D.E., Derre L., Rodziewicz-Motowidło S., 2019/01/11. Oncotarget, 10 (4) pp. 536-550. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F79CFFA532C9]
 
Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Connexin 43.
Trincot C.E., Xu W., Zhang H., Kulikauskas M.R., Caranasos T.G., Jensen B.C., Sabine A., Petrova T.V., Caron K.M., 2019/01/04. Circulation research, 124 (1) pp. 101-113. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9192022309DA]
IL-15 and a Two-Step Maturation Process Improve Bone Marrow-Derived Dendritic Cell Cancer Vaccine
Mookerjee Ananda, Graciotti Michele, Kandalaft Lana E., 2019/01/04. Cancers, 11 (1) p. 40.
[URN][DOI][Pmid][serval:BIB_3AE465562649]
 
Active Nano-targeting of Macrophages.
Gaspar N., Zambito G., Löwik CMWG, Mezzanotte L., 2019. Current pharmaceutical design, 25 (17) pp. 1951-1961. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9A17D79A11D6]
 
Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy.
Maio M., Coukos G., Ferrone S., Fox B.A., Fridman W.H., Garcia P.L., Lahn M., Provendier O., Russo V., Rüttinger D. et al., 2019/01. Cancer immunology, immunotherapy, 68 (1) pp. 1-9. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C44CE339457D]
Analysis of Secondary Structure Biases in Naturally Presented HLA-I Ligands.
Perez MAS, Bassani-Sternberg M., Coukos G., Gfeller D., Zoete V., 2019. Frontiers in immunology, 10 p. 2731. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BA3DEC8F83B0]
Combination of Synthetic Long Peptides and XCL1 Fusion Proteins Results in Superior Tumor Control.
Botelho N.K., Tschumi B.O., Hubbell J.A., Swartz M.A., Donda A., Romero P., 2019. Frontiers in immunology, 10 p. 294. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6975012892E2]
Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival.
Pyke R.M., Genolet R., Harari A., Coukos G., Gfeller D., Carter H., 2019. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 24 pp. 148-159. Peer-reviewed.
[URN][Pmid][serval:BIB_D49E37F7812C]
 
Determining Macrophage Polarization upon Metabolic Perturbation.
Liu P.S., Ho P.C., 2019. Methods in molecular biology, 1862 pp. 173-186. Peer-reviewed.
[DOI][Pmid][serval:BIB_5B2518331659]
Editorial: Novel Strategies for Anti-Tumor Vaccines.
Accolla R.S., Buonaguro L., Melief C., Rammensee H.G., Bassani-Sternberg M., 2019. Frontiers in immunology, 10 p. 3117. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_174539D18793]
High Peptide Dose Vaccination Promotes the Early Selection of Tumor Antigen-Specific CD8 T-Cells of Enhanced Functional Competence.
Carretero-Iglesia L., Couturaud B., Baumgaertner P., Schmidt J., Maby-El Hajjami H., Speiser D.E., Hebeisen M., Rufer N., 2019. Frontiers in immunology, 10 p. 3016. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_7933896A736E]
ILC2s: New Actors in Tumor Immunity.
Ercolano G., Falquet M., Vanoni G., Trabanelli S., Jandus C., 2019. Frontiers in immunology, 10 p. 2801. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_24E7A73B150C]
 
Immunophenotyping of Human Innate Lymphoid Cells.
Trabanelli S., Gomez-Cadena A., Jandus C., 2019. Methods in molecular biology, 2032 pp. 179-192. Peer-reviewed.
[DOI][Pmid][serval:BIB_C2BF71943F11]
 
La médecine personnalisée en oncologie dans: Médecine Personnalisée
Colomer-Lahiguera S., Coukos G., Peters S., Kandalaft L., Michielin O., Eicher M., 2019. dans Médecine Personnalisée, Académie Suisse de Sciences Médicales.
[serval:BIB_B2FAEFC8A271]
Low Avidity T Cells Do Not Hinder High Avidity T Cell Responses Against Melanoma
Ioannidou K., Randin O., Semilietof A., Maby-El Hajjami H., Baumgaertner P., Vanhecke D., Speiser D. E., 2019. Front Immunol, 10 p. 2115.
[URN][DOI][serval:BIB_98667AD85B65]
 
Nanowire Sensors in Cancer.
Doucey M.A., Carrara S., 2019/01. Trends in biotechnology, 37 (1) pp. 86-99. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88B5EE02323E]
New therapeutic perspectives to manage refractory immune checkpoint-related toxicities.
Martins F., Sykiotis G.P., Maillard M., Fraga M., Ribi C., Kuntzer T., Michielin O., Peters S., Coukos G., Spertini F. et al., 2019/01. The Lancet. Oncology, 20 (1) pp. e54-e64. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_42DB9145A8A7]
Targeting Adenosine in Cancer Immunotherapy to Enhance T-Cell Function.
Vigano S., Alatzoglou D., Irving M., Ménétrier-Caux C., Caux C., Romero P., Coukos G., 2019. Frontiers in immunology, 10 p. 925. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E661607B7DC8]
Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine.
Mohsen M.O., Vogel M., Riether C., Muller J., Salatino S., Ternette N., Gomes A.C., Cabral-Miranda G., El-Turabi A., Ruedl C. et al., 2019. Frontiers in immunology, 10 p. 1015. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_90783492E7F6]
2018
 
Rational Design, Synthesis, and Pharmacological Characterization of Novel Ghrelin Receptor Inverse Agonists as Potential Treatment against Obesity-Related Metabolic Diseases.
Daina A., Giuliano C., Pietra C., Wang J., Chi Y., Zou Z., Li F., Yan Z., Zhou Y., Guainazzi A. et al., 2018/12/27. Journal of medicinal chemistry, 61 (24) pp. 11039-11060. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_99AA6CB8899E]
 
Sparks Fly in PGE2-Modulated Macrophage Polarization.
Franco F., Wenes M., Ho P.C., 2018/12/18. Immunity, 49 (6) pp. 987-989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_843A58D94237]
 
The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands.
Gfeller D., Guillaume P., Michaux J., Pak H.S., Daniel R.T., Racle J., Coukos G., Bassani-Sternberg M., 2018/12/15. Journal of immunology, 201 (12) pp. 3705-3716. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7CB706F40FEB]
 
Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease.
Nisa L., Barras D., Medová M., Aebersold D.M., Medo M., Poliaková M., Koch J., Bojaxhiu B., Eliçin O., Dettmer M.S. et al., 2018/12. Molecular cancer research, 16 (12) pp. 1912-1926. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_13A592D7547E]
Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome.
Mylonas R., Beer I., Iseli C., Chong C., Pak H.S., Gfeller D., Coukos G., Xenarios I., Müller M., Bassani-Sternberg M., 2018/12. Molecular & cellular proteomics, 17 (12) pp. 2347-2357. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A79DB078A6D8]
 
Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor.
Soler M., Li X., John-Herpin A., Schmidt J., Coukos G., Altug H., 2018/11/26. ACS sensors, 3 (11) pp. 2286-2295. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_03777D375057]
The conserved threonine-rich region of the HCF-1<sub>PRO</sub> repeat activates promiscuous OGT:UDP-GlcNAc glycosylation and proteolysis activities.
Kapuria V., Röhrig U.F., Waridel P., Lammers F., Borodkin V.S., van Aalten DMF, Zoete V., Herr W., 2018/11/16. The Journal of biological chemistry, 293 (46) pp. 17754-17768. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2C5B11AB86FD]
 
Induction of Paracrine Signaling in Metastatic Melanoma Cells by PPARγ Agonist Rosiglitazone Activates Stromal Cells and Enhances Tumor Growth.
Pich C., Meylan P., Mastelic-Gavillet B., Nguyen T.N., Loyon R., Trang B.K., Moser H., Moret C., Goepfert C., Hafner J. et al., 2018/11/15. Cancer research, 78 (22) pp. 6447-6461. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_80BF8E0173C8]
 
Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.
Stanczak M.A., Siddiqui S.S., Trefny M.P., Thommen D.S., Boligan K.F., von Gunten S., Tzankov A., Tietze L., Lardinois D., Heinzelmann-Schwarz V. et al., 2018/11/01. The Journal of clinical investigation, 128 (11) pp. 4912-4923. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BD376501B5A1]
 
Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts.
Koval A., Pieme C.A., Queiroz E.F., Ragusa S., Ahmed K., Blagodatski A., Wolfender J.L., Petrova T.V., Katanaev V.L., 2018/10/28. Cancer letters, 435 pp. 110-120. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DC69DC6196DF]
Transcriptional regulation of murine natural killer cell development, differentiation and maturation.
Held W., Jeevan-Raj B., Charmoy M., 2018/09. Cellular and molecular life sciences, 75 (18) pp. 3371-3379. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1E93DC8609A6]
 
Clinical and pharmacogenetic determinants of 5-fluorouracyl/leucovorin/irinotecan toxicity: Results of the PETACC-3 trial.
Tejpar S., Yan P., Piessevaux H., Dietrich D., Brauchli P., Klingbiel D., Fiocca R., Delorenzi M., Bosman F., Roth A.D., 2018/08. European journal of cancer, 99 pp. 66-77. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BEFEC6CAADF3]
Consensus guidelines for the use and interpretation of angiogenesis assays.
Nowak-Sliwinska P., Alitalo K., Allen E., Anisimov A., Aplin A.C., Auerbach R., Augustin H.G., Bates D.O., van Beijnum J.R., Bender RHF et al., 2018/08. Angiogenesis, 21 (3) pp. 425-532. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0B60945B0B6F]
 
Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome*
Roman Mylonas, Ilan Beer, Christian Iseli, Chloe Chong, Hui-Song Pak, David Gfeller, George Coukos, Ioannis Xenarios, Markus Müller, Michal Bassani-Sternberg, 2018/08. Molecular & Cellular Proteomics.
[DOI][serval:BIB_350667B275DE]
 
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Castro W., Chelbi S.T., Niogret C., Ramon-Barros C., Welten SPM, Osterheld K., Wang H., Rota G., Morgado L., Vivier E. et al., 2018/08. Nature immunology, 19 (8) pp. 809-820. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A76D5C40117C]
 
PD-1 Blockade Unleashes Effector Potential of Both High- and Low-Affinity Tumor-Infiltrating T Cells.
Martínez-Usatorre A., Donda A., Zehn D., Romero P., 2018/07/15. Journal of immunology, 201 (2) pp. 792-803. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_80FA2317E7F7]
CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos George, Romero P. et al., 2018/07/13. Journal for immunotherapy of cancer, 6 (1) p. 71. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_799B70627D11]
TCR signal strength controls thymic differentiation of iNKT cell subsets.
Tuttle K.D., Krovi S.H., Zhang J., Bedel R., Harmacek L., Peterson L.K., Dragone L.L., Lefferts A., Halluszczak C., Riemondy K. et al., 2018/07/09. Nature communications, 9 (1) p. 2650. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EED9B5A0E3A7]
 
Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways.
Young M., Dahoun T., Sokrat B., Arber C., Chen K.M., Bouvier M., Barth P., 2018/07/03. Proceedings of the National Academy of Sciences of the United States of America, 115 (27) pp. 7051-7056. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8C56DD9E0F4C]
Autocrine Adenosine Regulates Tumor Polyfunctional CD73<sup>+</sup>CD4<sup>+</sup> Effector T Cells Devoid of Immune Checkpoints.
Gourdin N., Bossennec M., Rodriguez C., Vigano S., Machon C., Jandus C., Bauché D., Faget J., Durand I., Chopin N. et al., 2018/07/01. Cancer research, 78 (13) pp. 3604-3618. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_028E2FB272C5]
 
Mitochondria: A master regulator in macrophage and T cell immunity.
Liu P.S., Ho P.C., 2018/07. Mitochondrion, 41 pp. 45-50. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F5461A5E94DF]
PROX1 is a transcriptional regulator of MMP14.
Gramolelli S., Cheng J., Martinez-Corral I., Vähä-Koskela M., Elbasani E., Kaivanto E., Rantanen V., Tuohinto K., Hautaniemi S., Bower M. et al., 2018/06/22. Scientific reports, 8 (1) p. 9531. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_52BE6D877F2E]
CD73 expression and clinical significance in human metastatic melanoma.
Monteiro I., Vigano S., Faouzi M., Treilleux I., Michielin O., Ménétrier-Caux C., Caux C., Romero P., de Leval L., 2018/06/01. Oncotarget, 9 (42) pp. 26659-26669. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_11E2460193C6]
 
Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness.
Costa Del Amo P., Lahoz-Beneytez J., Boelen L., Ahmed R., Miners K.L., Zhang Y., Roger L., Jones R.E., Marraco SAF, Speiser D.E. et al., 2018/06. PLoS biology, 16 (6) pp. e2005523. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D04E45903CAD]
 
Label-Free Optofluidic Nanobiosensor Enables Real-Time Analysis of Single-Cell Cytokine Secretion.
Li X., Soler M., Szydzik C., Khoshmanesh K., Schmidt J., Coukos G., Mitchell A., Altug H., 2018/06. Small, 14 (26) pp. e1800698. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_40E1FE30E6D5]
Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE).
Lill J.R., van Veelen P.A., Tenzer S., Admon A., Caron E., Elias J.E., Heck AJR, Marcilla M., Marino F., Müller M. et al., 2018/06. Proteomics, 18 (12) pp. e1800110. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_62FB4A93752F]
 
Overview of Genetically Engineered Mouse Models of Prostate Cancer and Their Applications in Drug Discovery.
Civenni G., Carbone G.M., Catapano C.V., 2018/06. Current protocols in pharmacology, 81 (1) pp. e39. Peer-reviewed.
[DOI][Pmid][serval:BIB_9384CE54E90F]
 
Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma.
Battistello E., Katanayeva N., Dheilly E., Tavernari D., Donaldson M.C., Bonsignore L., Thome M., Christie A.L., Murakami M.A., Michielin O. et al., 2018/05/24. Blood, 131 (21) pp. 2345-2356. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_628039C698E5]
The C-terminal extension landscape of naturally presented HLA-I ligands.
Guillaume P., Picaud S., Baumgaertner P., Montandon N., Schmidt J., Speiser D.E., Coukos G., Bassani-Sternberg M., Filippakopoulos P., Gfeller D., 2018/05/15. Proceedings of the National Academy of Sciences of the United States of America, 115 (20) pp. 5083-5088. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9B915FD9A9BB]
 
Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.
Fukumura D., Kloepper J., Amoozgar Z., Duda D.G., Jain R.K., 2018/05. Nature reviews. Clinical oncology, 15 (5) pp. 325-340. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4DAFF0202FDC]
Human innate lymphoid cells (ILCs): Toward a uniform immune-phenotyping.
Trabanelli S., Gomez-Cadena A., Salomé B., Michaud K., Mavilio D., Landis B.N., Jandus P., Jandus C., 2018/05. Cytometry. Part B, Clinical cytometry, 94 (3) pp. 392-399. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A2FB75F5FD09]
 
The challenges of modeling hormone receptor-positive breast cancer in mice.
Özdemir B.C., Sflomos G., Brisken C., 2018/05. Endocrine-related cancer, 25 (5) pp. R319-R330. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_17DA2E56C0C6]
 
Quantification of the next-generation oral anti-tumor drugs dabrafenib, trametinib, vemurafenib, cobimetinib, pazopanib, regorafenib and two metabolites in human plasma by liquid chromatography-tandem mass spectrometry.
Cardoso E., Mercier T., Wagner A.D., Homicsko K., Michielin O., Ellefsen-Lavoie K., Cagnon L., Diezi M., Buclin T., Widmer N. et al., 2018/04/15. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1083 pp. 124-136. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E8B0234B5672]
 
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer
Tanyi Janos L., Bobisse Sara, Ophir Eran, Tuyaerts Sandra, Roberti Annalisa, Genolet Raphael, Baumgartner Petra, Stevenson Brian J., Iseli Christian, Dangaj Denarda et al., 2018/04/11. Science Translational Medicine, 10 (436) pp. eaao5931.
[DOI][WoS][Pmid][serval:BIB_641968BB356B]
 
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.
Tanyi J.L., Bobisse S., Ophir E., Tuyaerts S., Roberti A., Genolet R., Baumgartner P., Stevenson B.J., Iseli C., Dangaj D. et al., 2018/04/11. Science translational medicine, 10 (436) pp. NA. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CBC10D090AEF]
 
T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.
Neubert N.J., Schmittnaegel M., Bordry N., Nassiri S., Wald N., Martignier C., Tillé L., Homicsko K., Damsky W., Maby-El Hajjami H. et al., 2018/04/11. Science translational medicine, 10 (436). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FE6933D4F057]
 
Immune-related adverse events of immune checkpoint inhibitors and the impact of sex-what we know and what we need to learn.
Özdemir B.C., Coukos G., Wagner A.D., 2018/04/01. Annals of oncology, 29 (4) p. 1067. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_888420F74085]
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Rius C., Attaf M., Tungatt K., Bianchi V., Legut M., Bovay A., Donia M., Thor Straten P., Peakman M., Svane I.M. et al., 2018/04/01. Journal of immunology, 200 (7) pp. 2263-2279. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5D3F0C23532F]
The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
Bady P., Kurscheid S., Delorenzi M., Gorlia T., van den Bent M.J., Hoang-Xuan K., Vauléon É., Gijtenbeek A., Enting R., Thiessen B. et al., 2018/04. Acta neuropathologica, 135 (4) pp. 601-615. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_424F6D3B26FB]
 
Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8<sup>+</sup> T Cells.
Bantug G.R., Fischer M., Grählert J., Balmer M.L., Unterstab G., Develioglu L., Steiner R., Zhang L., Costa ASH, Gubser P.M. et al., 2018/03/20. Immunity, 48 (3) pp. 542-555.e6. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_860F1556AA95]
Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.
Bobisse S., Genolet R., Roberti A., Tanyi J.L., Racle J., Stevenson B.J., Iseli C., Michel A., Le Bitoux M.A., Guillaume P. et al., 2018/03/15. Nature communications, 9 (1) p. 1092. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_10AE95ADCEE8]
High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome.
Chong C., Marino F., Pak H., Racle J., Daniel R.T., Müller M., Gfeller D., Coukos G., Bassani-Sternberg M., 2018/03. Molecular & cellular proteomics, 17 (3) pp. 533-548. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A056F0253744]
 
Innate lymphoid cells in antitumor immunity.
Salomé B., Jandus C., 2018/03. Journal of leukocyte biology, 103 (3) pp. 479-483. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F4D2A841BA31]
Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation.
Danilo M., Chennupati V., Silva J.G., Siegert S., Held W., 2018/02/20. Cell reports, 22 (8) pp. 2107-2117. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C287A133B463]
 
Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.
Yuan X., Yang M., Chen X., Zhang X., Sukhadia S., Musolino N., Bao H., Chen T., Xu C., Wang Q. et al., 2018/02. Cancer immunology, immunotherapy, 67 (2) pp. 329-339. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EF0FC7F11707]
 
Educational Tools to Introduce Computer-Aided Drug Design to Students and to the Public at Large.
Daina A., Blatter M.C., Gerritsen V.B., Zoete V., 2018/02/01. Chimia, 72 (1) pp. 55-61. Peer-reviewed.
[DOI][Pmid][serval:BIB_EB3DE0B6C325]
 
Metabolic adaptation of macrophages in chronic diseases.
Di Conza G., Ho P.C., 2018/02/01. Cancer letters, 414 pp. 250-256. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_886BEAF4AAA4]
 
Rationale for immunological approaches to breast cancer therapy.
Monnot G.C., Romero P., 2018/02. Breast, 37 pp. 187-195. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A20CA73FEEF5]
T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus.
Bovay A., Zoete V., Dolton G., Bulek A.M., Cole D.K., Rizkallah P.J., Fuller A., Beck K., Michielin O., Speiser D.E. et al., 2018/02. European journal of immunology, 48 (2) pp. 258-272. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_47E01B2BD815]
 
Tumour endothelial marker 1/endosialin-mediated targeting of human sarcoma.
Guo Y., Hu J., Wang Y., Peng X., Min J., Wang J., Matthaiou E., Cheng Y., Sun K., Tong X. et al., 2018/02. European journal of cancer, 90 pp. 111-121. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7E091004637B]
 
A Long-Distance Relay-tionship between Tumor and Bone.
Soukup K., Joyce J.A., 2018/01/16. Immunity, 48 (1) pp. 13-16. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8F1963FC24AF]
Organ-specific lymphatic vasculature: From development to pathophysiology.
Petrova T.V., Koh G.Y., 2018/01/02. The Journal of experimental medicine, 215 (1) pp. 35-49. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_41205D392493]
 
Characterization of Mouse Mesenteric Lymphatic Valve Structure and Function.
Sabine A., Davis M.J., Bovay E., Petrova T.V., 2018. Methods in molecular biology, 1846 pp. 97-129. Peer-reviewed.
[DOI][Pmid][serval:BIB_B2BA9D31B889]
Correction to: CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos G., Romero P. et al., 2018. Journal for Immunotherapy of Cancer, 6 (1) p. 92. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AE20F9B96389]
Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab.
Kowalczyk-Quintas C., Chevalley D., Willen L., Jandus C., Vigolo M., Schneider P., 2018. Frontiers in immunology, 9 p. 2698. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CF7EAEC93BBA]
Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice.
Wilson A., Fu H., Schiffrin M., Winkler C., Koufany M., Jouzeau J.Y., Bonnet N., Gilardi F., Renevey F., Luther S.A. et al., 2018. Frontiers in immunology, 9 p. 2573. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1326C9CC8F2A]
Lymphatic vessel density is associated with CD8<sup>+</sup> T cell infiltration and immunosuppressive factors in human melanoma.
Bordry N., Broggi MAS, de Jonge K., Schaeuble K., Gannon P.O., Foukas P.G., Danenberg E., Romano E., Baumgaertner P., Fankhauser M. et al., 2018. Oncoimmunology, 7 (8) pp. e1462878. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AD8EABFF0764]
 
Mass Spectrometry Based Immunopeptidomics for the Discovery of Cancer Neoantigens.
Bassani-Sternberg M., 2018. Methods in molecular biology, 1719 pp. 209-221. Peer-reviewed.
[DOI][Pmid][serval:BIB_CED5BE78B134]
 
Metabolic Control of CD8<sup>+</sup> T Cell Fate Decisions and Antitumor Immunity.
Zhang L., Romero P., 2018/01. Trends in molecular medicine, 24 (1) pp. 30-48. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FA3C9C58E397]
 
Modulation of the peripheral blood transcriptome by the ingestion of probiotic yoghurt and acidified milk in healthy, young men.
Burton K.J., Pimentel G., Zangger N., Vionnet N., Drai J., McTernan P.G., Pralong F.P., Delorenzi M., Vergères G., 2018. PloS one, 13 (2) pp. e0192947. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5A639D1DDB1C]
Multiple roles of lymphatic vessels in peripheral lymph node development.
Bovay E., Sabine A., Prat-Luri B., Kim S., Son K., Willrodt A.H., Olsson C., Halin C., Kiefer F., Betsholtz C. et al., 2018. The Journal of Experimental Medicine, 215 (11) pp. 2760-2777. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E43336AE208C]
Predicting Antigen Presentation-What Could We Learn From a Million Peptides?
Gfeller D., Bassani-Sternberg M., 2018. Frontiers in immunology, 9 p. 1716. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DD4188679B4B]
Prophylactic vs. Therapeutic Treatment With P2Et Polyphenol-Rich Extract Has Opposite Effects on Tumor Growth.
Lasso P., Gomez-Cadena A., Urueña C., Donda A., Martinez-Usatorre A., Barreto A., Romero P., Fiorentino S., 2018. Frontiers in oncology, 8 p. 356. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F7C41B0E6390]
 
Tumor infiltrating lymphocytes in lymph node metastases of stage III melanoma correspond to response and survival in nine patients treated with ipilimumab at the time of stage IV disease.
Diem S., Hasan Ali O., Ackermann C.J., Bomze D., Koelzer V.H., Jochum W., Speiser D.E., Mertz K.D., Flatz L., 2018/01. Cancer immunology, immunotherapy, 67 (1) pp. 39-45. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E3DB1269164A]
Tumor Resident Memory T Cells: New Players in Immune Surveillance and Therapy.
Dumauthioz N., Labiano S., Romero P., 2018. Frontiers in immunology, 9 p. 2076. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A1AD953828BB]
2017
Feeling Exhausted? Tuning Irf4 Energizes Dysfunctional T Cells.
Chennupati V., Held W., 2017/12/19. Immunity, 47 (6) pp. 1009-1011. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F6047C7A6B9F]
Natural antisense transcripts drive a regulatory cascade controlling c-MYC transcription.
Napoli S., Piccinelli V., Mapelli S.N., Pisignano G., Catapano C.V., 2017/12/02. RNA biology, 14 (12) pp. 1742-1755. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3E1D90E64A12]
 
Cancer immunotherapy full speed ahead.
Melero I., Navarro B., Teijeira A., Coukos G., 2017/12/01. Annals of oncology, 28 (suppl_12) pp. xii1-xii2. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DA57E8E33449]
 
Mechanisms regulating T-cell infiltration and activity in solid tumors.
Lanitis E., Dangaj D., Irving M., Coukos G., 2017/12/01. Annals of oncology, 28 (suppl_12) pp. xii18-xii32. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FE2398AAD635]
 
Obesity and the tumor microenvironment.
Olson O.C., Quail D.F., Joyce J.A., 2017/12/01. Science, 358 (6367) pp. 1130-1131. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_99607CEF07CC]
 
A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux.
Jena P.V., Roxbury D., Galassi T.V., Akkari L., Horoszko C.P., Iaea D.B., Budhathoki-Uprety J., Pipalia N., Haka A.S., Harvey J.D. et al., 2017/11/28. ACS nano, 11 (11) pp. 10689-10703. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1B6139F6FBC4]
 
Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression.
Bakst R.L., Xiong H., Chen C.H., Deborde S., Lyubchik A., Zhou Y., He S., McNamara W., Lee S.Y., Olson O.C. et al., 2017/11/15. Cancer research, 77 (22) pp. 6400-6414. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1F176978670A]
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data.
Racle J., de Jonge K., Baumgaertner P., Speiser D.E., Gfeller D., 2017/11/13. eLife, 6 pp. 1-25. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D4CC1AFA4588]
Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.
Yan D., Kowal J., Akkari L., Schuhmacher A.J., Huse J.T., West B.L., Joyce J.A., 2017/10/26. Oncogene, 36 (43) pp. 6049-6058. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_07614DBA0E81]
 
Peripheral Deletion of CD8 T Cells Requires p38 MAPK in Cross-Presenting Dendritic Cells.
Smith T., Lin X., Mello M., Marquardt K., Cheung J., Lu B., Sherman L.A., Verdeil G., 2017/10/15. Journal of immunology, 199 (8) pp. 2713-2720. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_53F45409F322]
All TIEd up: mechanisms of Schlemm's canal maintenance.
Bernier-Latmani J., Petrova T.V., 2017/10/02. The Journal of clinical investigation, 127 (10) pp. 3594-3597. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1B5F5B7FCAD4]
 
More T Cells versus Better T Cells in Patients with Breast Cancer.
Speiser D.E., Verdeil G., 2017/10. Cancer discovery, 7 (10) pp. 1062-1064. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3675736551F9]
RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation.
Kopparam J., Chiffelle J., Angelino P., Piersigilli A., Zangger N., Delorenzi M., Meylan E., 2017/10. Cell death and differentiation, 24 (10) pp. 1761-1771. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9C34911CB2F4]
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.
Trabanelli S., Chevalier M.F., Martinez-Usatorre A., Gomez-Cadena A., Salomé B., Lecciso M., Salvestrini V., Verdeil G., Racle J., Papayannidis C. et al., 2017/09/19. Nature communications, 8 (1) p. 593. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_40D92F523196]
 
Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.
Fankhauser M., Broggi MAS, Potin L., Bordry N., Jeanbart L., Lund A.W., Da Costa E., Hauert S., Rincon-Restrepo M., Tremblay C. et al., 2017/09/13. Science translational medicine, 9 (407) pp. 1-13. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C55698C8F509]
Curtailed T-cell activation curbs effector differentiation and generates CD8<sup>+</sup> T cells with a naturally-occurring memory stem cell phenotype.
Zanon V., Pilipow K., Scamardella E., De Paoli F., De Simone G., Price D.A., Martinez Usatorre A., Romero P., Mavilio D., Roberto A. et al., 2017/09. European journal of immunology, 47 (9) pp. 1468-1476. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_13B86EE92733]
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