Department of Fundamental Oncology

Publications | Phd and Masters theses

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659 publications

... | 2017 | 2016 | 2015 | ...
2017
 
Intestinal lymphatic vasculature: structure, mechanisms and functions.
Bernier-Latmani J., Petrova T.V., 2017/09. Nature reviews. Gastroenterology & hepatology, 14 (9) pp. 510-526. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_50281243EFF5]
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.
Janouskova H., El Tekle G., Bellini E., Udeshi N.D., Rinaldi A., Ulbricht A., Bernasocchi T., Civenni G., Losa M., Svinkina T. et al., 2017/09. Nature medicine, 23 (9) pp. 1046-1054. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9533B4127F39]
 
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Liu P.S., Wang H., Li X., Chao T., Teav T., Christen S., Di Conza G., Cheng W.C., Chou C.H., Vavakova M. et al., 2017/09. Nature immunology, 18 (9) pp. 985-994. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CA3F4F3BEF1D]
 
A Case for a Human Immuno-Peptidome Project Consortium.
Caron E., Aebersold R., Banaei-Esfahani A., Chong C., Bassani-Sternberg M., 2017/08/15. Immunity, 47 (2) pp. 203-208. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F474823E2EBD]
 
Label-free identification of activated T lymphocytes through tridimensional microsensors on chip.
Rollo E., Tenaglia E., Genolet R., Bianchi E., Harari A., Coukos G., Guiducci C., 2017/08/15. Biosensors & bioelectronics, 94 pp. 193-199. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8DDCB6B9A58E]
Long-Term Engraftment of Primary Bone Marrow Stromal Cells Repairs Niche Damage and Improves Hematopoietic Stem Cell Transplantation.
Abbuehl J.P., Tatarova Z., Held W., Huelsken J., 2017/08/03. Cell stem cell, 21 (2) pp. 241-255.e6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_22612957789F]
 
Metabolic Regulation of Tregs in Cancer: Opportunities for Immunotherapy.
Wang H., Franco F., Ho P.C., 2017/08. Trends in cancer, 3 (8) pp. 583-592. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_49A26876BD66]
 
Microenvironmental regulation of tumour angiogenesis.
De Palma M., Biziato D., Petrova T.V., 2017/08. Nature reviews. Cancer, 17 (8) pp. 457-474. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA44FA8CECE2]
 
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF.
Quail D.F., Olson O.C., Bhardwaj P., Walsh L.A., Akkari L., Quick M.L., Chen I.C., Wendel N., Ben-Chetrit N., Walker J. et al., 2017/08. Nature cell biology, 19 (8) pp. 974-987. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FE7ACE5982F5]
TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.
Allard M., Couturaud B., Carretero-Iglesia L., Duong M.N., Schmidt J., Monnot G.C., Romero P., Speiser D.E., Hebeisen M., Rufer N., 2017/07/20. JCI insight, 2 (14) pp. e92570. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_336570E7506E]
The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes.
Jeevan-Raj B., Gehrig J., Charmoy M., Chennupati V., Grandclément C., Angelino P., Delorenzi M., Held W., 2017/07/18. Cell reports, 20 (3) pp. 613-626. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_87F6877665CF]
 
In silico and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.
Schmidt J., Guillaume P., Dojcinovic D., Karbach J., Coukos G., Luescher I., 2017/07/14. The Journal of biological chemistry, 292 (28) pp. 11840-11849. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5AC2BD6D841F]
 
Characterisation of multifocal breast cancer using the 70-gene signature in clinical low-risk patients enrolled in the EORTC 10041/BIG 03-04 MINDACT trial.
Aalders K.C., Kuijer A., Straver M.E., Slaets L., Litiere S., Viale G., Van't Veer L.J., Glas A.M., Delorenzi M., van Dalen T. et al., 2017/07. European journal of cancer, 79 pp. 98-105. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_076642AE6AC4]
 
Identification of innate lymphoid cells in single-cell RNA-Seq data.
Suffiotti M., Carmona S.J., Jandus C., Gfeller D., 2017/07. Immunogenetics, 69 (7) pp. 439-450. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_746D02A9A722]
Rapid and Continued T-Cell Differentiation into Long-term Effector and Memory Stem Cells in Vaccinated Melanoma Patients.
Gannon P.O., Baumgaertner P., Huber A., Iancu E.M., Cagnon L., Abed Maillard S., Maby-El Hajjami H., Speiser D.E., Rufer N., 2017/07/01. Clinical cancer research, 23 (13) pp. 3285-3296. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_714D67883897]
 
Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells.
Genini D., Brambilla L., Laurini E., Merulla J., Civenni G., Pandit S., D'Antuono R., Perez L., Levy D.E., Pricl S. et al., 2017/06/20. Proceedings of the National Academy of Sciences of the United States of America, 114 (25) pp. E4924-E4933. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A76A436E8778]
Characterization of perfluorocarbon relaxation times and their influence on the optimization of fluorine-19 MRI at 3 tesla.
Colotti R., Bastiaansen JAM, Wilson A., Flögel U., Gonzales C., Schwitter J., Stuber M., van Heeswijk R.B., 2017/06. Magnetic resonance in medicine, 77 (6) pp. 2263-2271. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8F0AA67F9966]
Immunoregulation of Dendritic Cell Subsets by Inhibitory Receptors in Urothelial Cancer.
Chevalier M.F., Bohner P., Pieraerts C., Lhermitte B., Gourmaud J., Nobile A., Rotman S., Cesson V., Martin V., Legris A.S. et al., 2017/06. European urology, 71 (6) pp. 854-857. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_001B02D71DD0]
 
Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries.
Ho P.C., Kaech S.M., 2017/06. Current opinion in immunology, 46 pp. 38-44. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38C4B8D3BCD4]
A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.
Pisignano G., Napoli S., Magistri M., Mapelli S.N., Pastori C., Di Marco S., Civenni G., Albino D., Enriquez C., Allegrini S. et al., 2017/05/30. Nature communications, 8 p. 15622. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1BADDEDD8870]
The ovarian cancer oncobiome.
Banerjee S., Tian T., Wei Z., Shih N., Feldman M.D., Alwine J.C., Coukos G., Robertson E.S., 2017/05/30. Oncotarget, 8 (22) pp. 36225-36245. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E109B279F39B]
 
The pathogen-related yeast protein Pry1, a member of the CAP protein superfamily, is a fatty acid-binding protein.
Darwiche R., Mène-Saffrané L., Gfeller D., Asojo O.A., Schneiter R., 2017/05/19. The Journal of biological chemistry, 292 (20) pp. 8304-8314. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9BD5446EEF7B]
TCF1(+) hepatitis C virus-specific CD8(+) T cells are maintained after cessation of chronic antigen stimulation.
Wieland D., Kemming J., Schuch A., Emmerich F., Knolle P., Neumann-Haefelin C., Held W., Zehn D., Hofmann M., Thimme R., 2017/05/03. Nature communications, 8 p. 15050. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BC4DAD6A8908]
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.
Dienstmann R., Mason M.J., Sinicrope F.A., Phipps A.I., Tejpar S., Nesbakken A., Danielsen S.A., Sveen A., Buchanan D.D., Clendenning M. et al., 2017/05/01. Annals of oncology, 28 (5) pp. 1023-1031. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8E7F51316719]
Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents.
Olson O.C., Kim H., Quail D.F., Foley E.A., Joyce J.A., 2017/04/04. Cell reports, 19 (1) pp. 101-113. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D85BBAB8A64B]
 
Broad and Conserved Immune Regulation by Genetically Heterogeneous Melanoma Cells.
Neubert N.J., Tillé L., Barras D., Soneson C., Baumgaertner P., Rimoldi D., Gfeller D., Delorenzi M., Fuertes Marraco S.A., Speiser D.E., 2017/04/01. Cancer research, 77 (7) pp. 1623-1636. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F63C0C97A59]
Integrative clinicopathological and molecular analyses of angioimmunoblastic T-cell lymphoma and other nodal lymphomas of follicular helper T-cell origin.
Dobay M.P., Lemonnier F., Missiaglia E., Bastard C., Vallois D., Jais J.P., Scourzic L., Dupuy A., Fataccioli V., Pujals A. et al., 2017/04. Haematologica, 102 (4) pp. e148-e151. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_55B41E65EEB9]
 
Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.
Frismantas V., Dobay M.P., Rinaldi A., Tchinda J., Dunn S.H., Kunz J., Richter-Pechanska P., Marovca B., Pail O., Jenni S. et al., 2017/03/16. Blood, 129 (11) pp. e26-e37. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FBE7D6D662B1]
Metabolic origins of spatial organization in the tumor microenvironment.
Carmona-Fontaine C., Deforet M., Akkari L., Thompson C.B., Joyce J.A., Xavier J.B., 2017/03/14. Proceedings of the National Academy of Sciences of the United States of America, 114 (11) pp. 2934-2939. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4F0B877B8084]
Heterogeneity assessment of functional T cell avidity.
Ioannidou K., Baumgaertner P., Gannon P.O., Speiser M.F., Allard M., Hebeisen M., Rufer N., Speiser D.E., 2017/03/13. Scientific reports, 7 p. 44320. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_39C885ED43A7]
 
The Microenvironmental Landscape of Brain Tumors.
Quail D.F., Joyce J.A., 2017/03/13. Cancer cell, 31 (3) pp. 326-341. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_66A33B0C2A3A]
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules.
Daina A., Michielin O., Zoete V., 2017/03/03. Scientific reports, 7 p. 42717. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8806AF61D608]
 
Indoleamine 2,3-dioxygenase in psoriasis: a defective mechanism.
Trabanelli S., 2017/03. The British journal of dermatology, 176 (3) pp. 570-572. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_82F602E35435]
Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types.
Carmona S.J., Teichmann S.A., Ferreira L., Macaulay I.C., Stubbington M.J., Cvejic A., Gfeller D., 2017/03. Genome research, 27 (3) pp. 451-461. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9293ADF6E6AC]
 
Molecular Pathways: Deciphering Mechanisms of Resistance to Macrophage-Targeted Therapies.
Quail D.F., Joyce J.A., 2017/02/15. Clinical cancer research, 23 (4) pp. 876-884. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A52BFAD7DA3C]
Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens.
MacLachlan B.J., Greenshields-Watson A., Mason G.H., Schauenburg A.J., Bianchi V., Rizkallah P.J., Sewell A.K., Fuller A., Cole D.K., 2017/02/06. Journal of visualized experiments 120 p. 0. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B37051F6DB1F]
 
Intravesical Bacillus Calmette Guerin Combined with a Cancer Vaccine Increases Local T-Cell Responses in Non-muscle-Invasive Bladder Cancer Patients.
Derré L., Cesson V., Lucca I., Cerantola Y., Valerio M., Fritschi U., Vlamopoulos Y., Burruni R., Legris A.S., Dartiguenave F. et al., 2017/02/01. Clinical cancer research, 23 (3) pp. 717-725. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7E871163C3ED]
 
Deciphering HLA motifs across HLA peptidomes correctly predicts neo-antigens and identifies allostery in HLA specificity
Michal Bassani-Sternberg, Chloe Chong, Philippe Guillaume, Marthe Solleder, HuiSong Pak, Philippe O Gannon, Lana E Kandalaft, George Coukos, David Gfeller, 2017/01/06..
[DOI][serval:BIB_3D78DB6DB74B]
 
T memory stem cells in health and disease.
Gattinoni L., Speiser D.E., Lichterfeld M., Bonini C., 2017/01/06. Nature medicine, 23 (1) pp. 18-27. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D7CE18B9CA28]
'Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization.
Müller M., Gfeller D., Coukos G., Bassani-Sternberg M., 2017. Frontiers in Immunology, 8 p. 1367. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A4DBE7C295A9]
A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors.
Turrini R., Merlo A., Martorelli D., Faè D.A., Sommaggio R., Montagner I.M., Barbieri V., Marin O., Zanovello P., Dolcetti R. et al., 2017. Oncoimmunology, 6 (4) pp. e1304338. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8CBC1FEC9495]
Alpha-Galactosylceramide/CD1d-Antibody Fusion Proteins Redirect Invariant Natural Killer T Cell Immunity to Solid Tumors and Promote Prolonged Therapeutic Responses.
Zhang L., Donda A., 2017. Frontiers in immunology, 8 p. 1417. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FC07385441DB]
 
ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells.
Lecciso M., Ocadlikova D., Sangaletti S., Trabanelli S., De Marchi E., Orioli E., Pegoraro A., Portararo P., Jandus C., Bontadini A. et al., 2017. Frontiers in immunology, 8 p. 1918. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_321E5982053C]
 
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia I.C., Lagarrigue S., Giralt A., Martinez-Carreres L., Zanou N., Denechaud P.D., Castillo-Armengol J., Chavey C., Orpinell M., Delacuisine B. et al., 2017. Molecular Cell, 68 (2) pp. 336-349.e6. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F02666506F7E]
 
Correlation between podoplanin expression and extracapsular spread in squamous cell carcinoma of the oral cavity using subjective immunoreactivity scores and semiquantitative image analysis.
Mermod M., Bongiovanni M., Petrova T.V., Dubikovskaya E.A., Simon C., Tolstonog G., Monnier Y., 2017/01. Head & neck, 39 (1) pp. 98-108. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8A5414AD1E48]
Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function.
Meens M.J., Kutkut I., Rochemont V., Dubrot J., Kaladji F.R., Sabine A., Lyons O., Hendrikx S., Bernier-Latmani J., Kiefer F. et al., 2017. PloS one, 12 (7) pp. e0181476. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C8459DCFE56A]
 
Cyclophosphamide treatment regulates the balance of functional/exhausted tumor-specific CD8(+) T cells.
Hanoteau A., Henin C., Svec D., Bisilliat Donnet C., Denanglaire S., Colau D., Romero P., Leo O., Van den Eynde B., Moser M., 2017. Oncoimmunology, 6 (8) pp. e1318234. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C347ED090FBF]
Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity.
Bassani-Sternberg M., Chong C., Guillaume P., Solleder M., Pak H., Gannon P.O., Kandalaft L.E., Coukos G., Gfeller D., 2017. PLoS Computational Biology, 13 (8) pp. e1005725. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0F969601F848]
Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses.
Spodzieja M., Lach S., Iwaszkiewicz J., Cesson V., Kalejta K., Olive D., Michielin O., Speiser D.E., Zoete V., Derré L. et al., 2017. PloS one, 12 (6) pp. e0179201.
[URN][DOI][WoS][Pmid][serval:BIB_8C02B51C71F2]
 
Dysregulated Innate Lymphocytes in Patients With Primary Antibody Deficiency Treated With Intravenous Immunoglobulin.
Vigano S., Trabanelli S., Indulsi F., Salomé B., Harari A., Romero P., Helbling A., Jandus C., Jandus P., 2017. Journal of investigational allergology & clinical immunology, 27 (6) pp. 394-396. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AFE710182D6B]
Editorial: Immunometabolic Regulations in Adaptive and Innate Immune Cells Shapes and Re-Directs Host Immunity.
Ho P.C., Hess C., 2017. Frontiers in immunology, 8 p. 852. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED9C27EAFE82]
Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.
Irving M., Vuillefroy de Silly R., Scholten K., Dilek N., Coukos G., 2017. Frontiers in immunology, 8 p. 267. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E326B4204C76]
Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms
Presotto D., Erdes E., Duong M.N., Allard M., Regamey P.O., Quadroni M., Doucey M.A., Rufer N., Hebeisen M., 2017. Frontiers in Immunology, 8 p. 1564. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_979725518892]
ILC2-modulated T cell-to-MDSC balance is associated with bladder cancer recurrence.
Chevalier M.F., Trabanelli S., Racle J., Salomé B., Cesson V., Gharbi D., Bohner P., Domingos-Pereira S., Dartiguenave F., Fritschi A.S. et al., 2017. The Journal of Clinical Investigation, 127 (8) pp. 2916-2929. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FA350D3E0400]
Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer.
Leftin A., Ben-Chetrit N., Klemm F., Joyce J.A., Koutcher J.A., 2017. PloS one, 12 (9) pp. e0184765. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5D3507371177]
Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy.
Facciabene A., De Sanctis F., Pierini S., Reis E.S., Balint K., Facciponte J., Rueter J., Kagabu M., Magotti P., Lanitis E. et al., 2017. Oncoimmunology, 6 (9) pp. e1326442. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_69B217E99597]
Mitochondrial Control and Guidance of Cellular Activities of T Cells.
Chao T., Wang H., Ho P.C., 2017. Frontiers in immunology, 8 p. 473. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_16BAFFED261C]
 
Mutations in JAK2 and Calreticulin genes are associated with specific alterations of the immune system in myelofibrosis.
Romano M., Sollazzo D., Trabanelli S., Barone M., Polverelli N., Perricone M., Forte D., Luatti S., Cavo M., Vianelli N. et al., 2017. Oncoimmunology, 6 (10) pp. e1345402. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DCB92201356B]
 
The Binding Mode of N-Hydroxyamidines to Indoleamine 2,3-Dioxygenase 1 (IDO1).
Röhrig U.F., Zoete V., Michielin O., 2017. Biochemistry, 56 (33) pp. 4323-4325. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B02CF9601B42]
 
The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β2-Microglobulin through Distinct Binding Sites.
Merkle P.S., Irving M., Hongjian S., Ferber M., Jørgensen TJD, Scholten K., Luescher I., Coukos G., Zoete V., Cuendet M.A. et al., 2017. Biochemistry, 56 (30) pp. 3945-3961. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7CF39E44F352]
 
The Vast Universe of T Cell Diversity: Subsets of Memory Cells and Their Differentiation.
Jandus C., Usatorre A.M., Viganò S., Zhang L., Romero P., 2017. Methods in molecular biology, 1514 pp. 1-17. Peer-reviewed.
[DOI][Pmid][serval:BIB_3B7AD728CB93]
TIE-2 expressing monocytes in human cancers.
Turrini R., Pabois A., Xenarios I., Coukos G., Delaloye J.F., Doucey M.A., 2017. Oncoimmunology, 6 (4) pp. e1303585. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7D0E518DFF81]
2016
 
Targeting transcriptional co-activators in advanced prostate cancer.
Groner A.C., Brown M., Theurillat J.P., 2016/12/16. Cell cycle, 15 (24) pp. 3333-3334. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7473DDE09801]
Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.
Coutaz M., Hurrell B.P., Auderset F., Wang H., Siegert S., Eberl G., Ho P.C., Radtke F., Tacchini-Cottier F., 2016/12/15. Scientific reports, 6 p. 39117. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6327A7D47779]
Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.
Revandkar A., Perciato M.L., Toso A., Alajati A., Chen J., Gerber H., Dimitrov M., Rinaldi A., Delaleu N., Pasquini E. et al., 2016/12/12. Nature communications, 7 p. 13719. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1FC6B49B76D3]
 
Combine and Conquer: Double CTLA-4 and PD-1 Blockade Combined with Whole Tumor Antigen Vaccine Cooperate to Eradicate Tumors.
Homicsko K., Duraiswamy J., Doucey M.A., Coukos G., 2016/12/01. Cancer research, 76 (23) pp. 6765-6767. Peer-reviewed.
[DOI][Pmid][serval:BIB_611A58A2720E]
 
MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression.
Dallavalle C., Albino D., Civenni G., Merulla J., Ostano P., Mello-Grand M., Rossi S., Losa M., D'Ambrosio G., Sessa F. et al., 2016/12/01. The Journal of clinical investigation, 126 (12) pp. 4585-4602. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CCE872B9EF32]
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies.
Bowman R.L., Klemm F., Akkari L., Pyonteck S.M., Sevenich L., Quail D.F., Dhara S., Simpson K., Gardner E.E., Iacobuzio-Donahue C.A. et al., 2016/11/22. Cell reports, 17 (9) pp. 2445-2459. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D0474EC65CDA]
The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment.
Albino D., Civenni G., Rossi S., Mitra A., Catapano C.V., Carbone G.M., 2016/11/22. Oncotarget, 7 (47) pp. 76756-76768. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5660C725915A]
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
Bassani-Sternberg M., Bräunlein E., Klar R., Engleitner T., Sinitcyn P., Audehm S., Straub M., Weber J., Slotta-Huspenina J., Specht K. et al., 2016/11/21. Nature communications, 7 p. 13404. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7CEBBFB3FC0C]
Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing.
Royer-Bertrand B., Torsello M., Rimoldi D., El Zaoui I., Cisarova K., Pescini-Gobert R., Raynaud F., Zografos L., Schalenbourg A., Speiser D. et al., 2016/11/03. American journal of human genetics, 99 (5) pp. 1190-1198. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_035A22A1A6AE]
 
Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
Reijneveld J.C., Taphoorn M.J., Coens C., Bromberg J.E., Mason W.P., Hoang-Xuan K., Ryan G., Hassel M.B., Enting R.H., Brandes A.A. et al., 2016/11. The Lancet. Oncology, 17 (11) pp. 1533-1542. Peer-reviewed.
[DOI][Pmid][serval:BIB_1893B983EDE5]
 
Magnetic nanoparticle-induced hyperthermia with appropriate payloads: Paul Ehrlich's "magic (nano)bullet" for cancer theranostics?
Datta N.R., Krishnan S., Speiser D.E., Neufeld E., Kuster N., Bodis S., Hofmann H., 2016/11. Cancer treatment reviews, 50 pp. 217-227. Peer-reviewed.
[DOI][Pmid][serval:BIB_B8DE105EED9A]
 
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.
Domingo E., Freeman-Mills L., Rayner E., Glaire M., Briggs S., Vermeulen L., Fessler E., Medema J.P., Boot A., Morreau H. et al., 2016/11. The lancet. Gastroenterology & hepatology, 1 (3) pp. 207-216. Peer-reviewed.
[DOI][Pmid][serval:BIB_ABD4B72A8778]
 
Tumor Regression and Delayed Onset Toxicity Following B7-H4 CAR T Cell Therapy.
Smith J.B., Lanitis E., Dangaj D., Buza E., Poussin M., Stashwick C., Scholler N., Powell D.J., 2016/11. Molecular therapy : the journal of the American Society of Gene Therapy, 24 (11) pp. 1987-1999. Peer-reviewed.
[DOI][Pmid][serval:BIB_EC7C7B783578]
A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire.
Oberle S.G., Hanna-El-Daher L., Chennupati V., Enouz S., Scherer S., Prlic M., Zehn D., 2016/10/11. Cell reports, 17 (3) pp. 627-635. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5BEF45DA9A4E]
 
Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope
Baumgaertner P., Costa Nunes C., Cachot A., Maby-El Hajjami H., Cagnon L., Braun M., Derré L., Rivals J.-P., Rimoldi D., Gnjatic S. et al., 2016/10/02. OncoImmunology, 5 (10) pp. e1216290.
[DOI][WoS][Pmid][serval:BIB_B9A2EC467477]
STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation.
Yan D., Wang H.W., Bowman R.L., Joyce J.A., 2016/09/13. Cell reports, 16 (11) pp. 2914-2927. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6B0AE4F9D236]
 
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).
Röhrig U.F., Majjigapu S.R., Caldelari D., Dilek N., Reichenbach P., Ascencao K., Irving M., Coukos G., Vogel P., Zoete V. et al., 2016/09/01. Bioorganic & medicinal chemistry letters, 26 (17) pp. 4330-4333. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9DF2682ECDFF]
 
Aphanin, a triterpenoid from Amoora rohituka inhibits K-Ras mutant activity and STAT3 in pancreatic carcinoma cells.
Rabi T., Catapano C.V., 2016/09. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 37 (9) pp. 12455-12464. Peer-reviewed.
[DOI][Pmid][serval:BIB_CDA68D029121]
 
Endothelial Cell Responses to Biomechanical Forces in Lymphatic Vessels.
Sabine A., Saygili Demir C., Petrova T.V., 2016/09/01. Antioxidants & redox signaling, 25 (7) pp. 451-465. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F058954BCABC]
 
Prediction of occult lymph node metastasis in squamous cell carcinoma of the oral cavity and the oropharynx using peritumoral Prospero homeobox protein 1 lymphatic nuclear quantification.
Mermod M., Bongiovanni M., Petrova T.V., Dubikovskaya E.A., Simon C., Tolstonog G., Monnier Y., 2016/09. Head & neck, 38 (9) pp. 1407-1415. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AC7C98A91446]
70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.
Cardoso F., van't Veer L.J., Bogaerts J., Slaets L., Viale G., Delaloge S., Pierga J.Y., Brain E., Causeret S., DeLorenzi M. et al., 2016/08/25. The New England journal of medicine, 375 (8) pp. 717-729. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D8474667A7D5]
High antigen levels induce an exhausted phenotype in a chronic infection without impairing T cell expansion and survival.
Utzschneider D.T., Alfei F., Roelli P., Barras D., Chennupati V., Darbre S., Delorenzi M., Pinschewer D.D., Zehn D., 2016/08/22. The Journal of experimental medicine, 213 (9) pp. 1819-1834. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B2EBEA9B2D32]
T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections.
Utzschneider D.T., Charmoy M., Chennupati V., Pousse L., Ferreira D.P., Calderon-Copete S., Danilo M., Alfei F., Hofmann M., Wieland D. et al., 2016/08/16. Immunity, 45 (2) pp. 415-427. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_26E58D22D474]
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A., Frera G., Lugrin J., Jamilloux Y., Hsu E.T., Tardivel A., De Gassart A., Zaffalon L., Bujisic B., Siegert S. et al., 2016/08/09. Proceedings of the National Academy of Sciences of the United States of America, 113 (32) pp. E4671-80. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_29BEBCA2CFB2]
TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.
Prudova A., Gocheva V., Auf dem Keller U., Eckhard U., Olson O.C., Akkari L., Butler G.S., Fortelny N., Lange P.F., Mark J.C. et al., 2016/08/09. Cell reports, 16 (6) pp. 1762-1773. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EFC4B030CCF3]
A Well-Controlled Experimental System to Study Interactions of Cytotoxic T Lymphocytes with Tumor Cells.
Neubert N.J., Soneson C., Barras D., Baumgaertner P., Rimoldi D., Delorenzi M., Fuertes Marraco S.A., Speiser D.E., 2016/08. Frontiers In Immunology, 7 p. 326. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BEB40E0CCE6B]
 
Mass spectrometry-based antigen discovery for cancer immunotherapy.
Bassani-Sternberg M., Coukos G., 2016/08. Current opinion in immunology, 41 pp. 9-17. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B7C4824CBB21]
 
Microenvironmental InterFereNce of metabolism regulates chemosensitivity.
Akkari L., Joyce J.A., 2016/08. Cell research, 26 (8) pp. 867-868. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F79936FDD183]
 
Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.
Chennupati V., Koch U., Coutaz M., Scarpellino L., Tacchini-Cottier F., Luther S.A., Radtke F., Zehn D., MacDonald H.R., 2016/08/01. Journal of immunology, 197 (3) pp. 771-782. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D6B2134FFAED]
 
CD69 Deficiency Enhances the Host Response to Vaccinia Virus Infection through Altered NK Cell Homeostasis.
Notario L., Alari-Pahissa E., de Molina A., Lauzurica P., 2016/07/15. Journal of virology, 90 (14) pp. 6464-6474. Peer-reviewed.
[DOI][Pmid][serval:BIB_C2CE7EC01BDD]
 
IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner.
Loyon R., Picard E., Mauvais O., Queiroz L., Mougey V., Pallandre J.R., Galaine J., Mercier-Letondal P., Kellerman G., Chaput N. et al., 2016/07/01. Journal of immunology, 197 (1) pp. 85-96. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8382F8338941]
 
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Albino D., Civenni G., Dallavalle C., Roos M., Jahns H., Curti L., Rossi S., Pinton S., D'Ambrosio G., Sessa F. et al., 2016/06/15. Cancer research, 76 (12) pp. 3629-3643. Peer-reviewed.
[DOI][Pmid][serval:BIB_BE66AF39ED9F]
 
Next-Generation Sequencing in Diffuse Large B-Cell Lymphoma Highlights Molecular Divergence and Therapeutic Opportunities: a LYSA Study.
Dubois S., Viailly P.J., Mareschal S., Bohers E., Bertrand P., Ruminy P., Maingonnat C., Jais J.P., Peyrouze P., Figeac M. et al., 2016/06/15. Clinical cancer research, 22 (12) pp. 2919-2928. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3974C4DCA3F8]
 
Traitement des cancers: n'oublions pas les enjeux humains et sociaux des progrès actuels et à venir!
Dietrich P.Y., Coukos G., Aapro M., 2016/05/18. Revue medicale suisse, 12 (519) pp. 963-964. Peer-reviewed.
[Pmid][serval:BIB_9ECEE908E0D8]
Cancer Vaccines in Ovarian Cancer: How Can We Improve?
Martin Lluesma S., Wolfer A., Harari A., Kandalaft L.E., 2016/05/03. Biomedicines, 4 (2) pp. NA. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_3E1510893037]
An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.
Knies D., Klobuch S., Xue S.A., Birtel M., Echchannaoui H., Yildiz O., Omokoko T., Guillaume P., Romero P., Stauss H. et al., 2016/04/19. Oncotarget, 7 (16) pp. 21199-21221. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_45D1E4A5393B]
 
TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.
Groner A.C., Cato L., de Tribolet-Hardy J., Bernasocchi T., Janouskova H., Melchers D., Houtman R., Cato A.C., Tschopp P., Gu L. et al., 2016/04/13. Cancer cell, 29 (6) pp. 846-858. Peer-reviewed.
[DOI][Pmid][serval:BIB_020FBFC9715D]
 
Opportunities in immunotherapy of ovarian cancer.
Coukos G., Tanyi J., Kandalaft L.E., 2016/04. Annals of oncology, 27 Suppl 1 pp. i11-i15. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_659109342A6F]
Phage Selection of Chemically Stabilized α-Helical Peptide Ligands.
Diderich P., Bertoldo D., Dessen P., Khan M.M., Pizzitola I., Held W., Huelsken J., Heinis C., 2016/03/20. ACS chemical biology, 11 (5) pp. 1422-1427. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_0A65DEA92978]
 
Identification of melanoma cells and lymphocyte subpopulations in lymph node metastases by FTIR imaging histopathology.
Wald N., Bordry N., Foukas P.G., Speiser D.E., Goormaghtigh E., 2016/02. Biochimica et biophysica acta, 1862 (2) pp. 202-212. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CC885309E0E0]
 
TCR-engineered T cells to treat tumors: Seeing but not touching?
Debets R., Donnadieu E., Chouaib S., Coukos G., 2016/02. Seminars in immunology, 28 (1) pp. 10-21. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D12442A44DA8]
 
A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome.
Schell M.J., Yang M., Missiaglia E., Delorenzi M., Soneson C., Yue B., Nebozhyn M.V., Loboda A., Bloom G., Yeatman T.J., 2016. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research, 22 (3) pp. 734-745. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EA19DDA38B3B]
 
A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.
Vecchione L., Gambino V., Raaijmakers J., Schlicker A., Fumagalli A., Russo M., Villanueva A., Beerling E., Bartolini A., Mollevi D.G. et al., 2016. Cell, 165 (2) pp. 317-330. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_482D42C5A0C1]
Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.
Vallois D., Dobay M.P., Morin R.D., Lemonnier F., Missiaglia E., Juilland M., Iwaszkiewicz J., Fataccioli V., Bisig B., Roberti A. et al., 2016. Blood, 128 (11) pp. 1490-1502. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A7AD3DD77F83]
Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition.
Alari-Pahissa E., Grandclément C., Jeevan-Raj B., Leclercq G., Veillette A., Held W., 2016. PLoS One, 11 (4) pp. e0153236. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6562347F8E45]
 
Anticancer Teamwork: Cross-Presenting Dendritic Cells Collaborate with Therapeutic Monoclonal Antibodies.
Robert-Tissot C., Speiser D.E., 2016. Cancer Discovery, 6 (1) pp. 17-19. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DF7D0310A078]
Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data.
Buhl I.K., Gerster S., Delorenzi M., Jensen T., Jensen P.B., Bosman F., Tejpar S., Roth A., Brunner N., Hansen A. et al., 2016. PloS one, 11 (5) pp. e0155123. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E521F016CAEB]
 
Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer.
Hasan Ali O., Diem S., Markert E., Jochum W., Kerl K., French L.E., Speiser D.E., Früh M., Flatz L., 2016. Oncoimmunology, 5 (11) pp. e1231292. Peer-reviewed.
[DOI][Pmid][serval:BIB_2E56945E5E7C]
 
Chromium-51 (51Cr) Release Assay to Assess Human T Cells for Functional Avidity and Tumor Cell Recognition
Baumgaertner Petra, Speiser Daniel E., Romero Pedro, Rufer Nathalie, Hebeisen Michael, 2016. Bio-protocol, 6 (16) pp. e1906.
[DOI][serval:BIB_67F9EDD3F2CB]
Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
Akkari L., Gocheva V., Quick M.L., Kester J.C., Spencer A.K., Garfall A.L., Bowman R.L., Joyce J.A., 2016. Genes and Development, 30 (2) pp. 220-232. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_34BF0625B509]
Comparison between direct and reverse electroporation of cells in situ: a simulation study.
Towhidi L., Khodadadi D., Maimari N., Pedrigi R.M., Ip H., Kis Z., Kwak B.R., Petrova T.W., Delorenzi M., Krams R., 2016. Physiological Reports, 4 (6) pp. e12673. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_139223D678E3]
 
Current tools for predicting cancer-specific T cell immunity.
Gfeller D., Bassani-Sternberg M., Schmidt J., Luescher I.F., 2016. Oncoimmunology, 5 (7) pp. e1177691. Peer-reviewed.
[DOI][Pmid][serval:BIB_D584F684242A]
 
Dielectric elastomer actuator for mechanical loading of 2D cell cultures.
Poulin A., Saygili Demir C., Rosset S., Petrova T.V., Shea H., 2016. Lab On A Chip, 16 (19) pp. 3788-3794. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F942E3146BE]
DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer.
Nygård S.B., Vainer B., Nielsen S.L., Bosman F., Tejpar S., Roth A., Delorenzi M., Brünner N., Budinska E., 2016. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research, 22 (7) pp. 1621-1631. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DB731FE14684]
Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient.
Siddiqui I., Erreni M., van Brakel M., Debets R., Allavena P., 2016. Journal For Immunotherapy of Cancer, 4 p. 21. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_0DF0F946B0B5]
 
Epitope located N-glycans impair the MHC-I epitope generation and presentation.
Chiritoiu G.N., Jandus C., Munteanu C.V., Ghenea S., Gannon P.O., Romero P., Petrescu S.M., 2016. Electrophoresis, 37 (11) pp. 1448-1460. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_46F3C01EE137]
 
From T cell “exhaustion” to anti-cancer immunity
Verdeil Grégory, Fuertes Marraco Silvia A., Murray Timothy, Speiser Daniel E., 2016/01. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1865 (1) pp. 49-57. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A25E5BACDB1A]
High-resolution 3D analysis of mouse small-intestinal stroma.
Bernier-Latmani J., Petrova T.V., 2016. Nature Protocols, 11 (9) pp. 1617-1629. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EB3B079FEAE6]
Identifying biological mechanisms for favorable cancer prognosis using non-hypothesis-driven iterative survival analysis.
Crespo I., Götz L., Liechti R., Coukos G., Doucey M.A., Xenarios I., 2016. NPJ systems biology and applications, 2 p. 16037. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_5114129C390E]
Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model.
Gomez-Cadena A., Urueña C., Prieto K., Martinez-Usatorre A., Donda A., Barreto A., Romero P., Fiorentino S., 2016. Cell Death and Disease, 7 (6) pp. e2243. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EBCCD2380B13]
Journal for immunotherapy of cancer reviewer acknowledgement 2015.
Romero P., 2016..
[URN][DOI][Pmid][serval:BIB_C9198B0D65AB]
 
MAF drives CD8(+) T-cell exhaustion.
Verdeil G., 2016. Oncoimmunology, 5 (2) pp. e1082707. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_ABC5C38C8BC5]
Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.
Zhang L., Tschumi B.O., Lopez-Mejia I.C., Oberle S.G., Meyer M., Samson G., Rüegg M.A., Hall M.N., Fajas L., Zehn D. et al., 2016. Cell Reports, 14 (5) pp. 1206-1217. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CB0706D22A19]
Metabolic communication in tumors: a new layer of immunoregulation for immune evasion.
Ho P.C., Liu P.S., 2016. Journal For Immunotherapy of Cancer, 4 p. 4. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_DD5E2FA95B5C]
 
Metabolic tug-of-war in tumors results in diminished T cell antitumor immunity.
Cheng W.C., Ho P.C., 2016. Oncoimmunology, 5 (4) pp. e1119355. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_054469C5F3CE]
Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells.
Scholz G., Jandus C., Zhang L., Grandclément C., Lopez-Mejia I.C., Soneson C., Delorenzi M., Fajas L., Held W., Dormond O. et al., 2016. Ebiomedicine, 4 pp. 50-61. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_5D18A226530B]
Mutation of the Traj18 gene segment using TALENs to generate Natural Killer T cell deficient mice.
Zhang J., Bedel R., Krovi S.H., Tuttle K.D., Zhang B., Gross J., Gapin L., Matsuda J.L., 2016. Scientific Reports, 6 p. 27375. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E4CC5332668F]
 
Neoantigen-based cancer immunotherapy.
Bobisse S., Foukas P.G., Coukos G., Harari A., 2016. Annals of Translational Medicine, 4 (14) p. 262. Peer-reviewed.
[DOI][Pmid][serval:BIB_F74C06B31066]
NK Cells Respond to Haptens by the Activation of Calcium Permeable Plasma Membrane Channels.
Grandclément C., Pick H., Vogel H., Held W., 2016. Plos One, 11 (3) pp. e0151031. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A63D15EF48B9]
NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions.
Ludigs K., Jandus C., Utzschneider D.T., Staehli F., Bessoles S., Dang A.T., Rota G., Castro W., Zehn D., Vivier E. et al., 2016. Nature Communications, 7 p. 10554. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8FDEF0BFED69]
 
NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling.
Zamoshnikova A., Groß C.J., Schuster S., Chen K.W., Wilson A., Tacchini-Cottier F., Schroder K., 2016. Immunobiology, 221 (2) pp. 341-346.
[DOI][WoS][Pmid][serval:BIB_F156CAAFEF5C]
Novel technologies and emerging biomarkers for personalized cancer immunotherapy.
Yuan J., Hegde P.S., Clynes R., Foukas P.G., Harari A., Kleen T.O., Kvistborg P., Maccalli C., Maecker H.T., Page D.B. et al., 2016. Journal For Immunotherapy of Cancer, 4 p. 3. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_EB4FE1C2D1D7]
 
Ovarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy.
Zsiros E., Dangaj D., June C.H., Kandalaft L.E., Coukos G., 2016. Oncoimmunology, 5 (5) pp. e1062210. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1852FDBECBFC]
 
Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?
Diem S., Keller F., Rüesch R., Maillard S.A., Speiser D.E., Dummer R., Siano M., Urner-Bloch U., Goldinger S.M., Flatz L., 2016. Journal of immunotherapy, 39 (9) pp. 379-382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F0FF08A6EC8D]
 
Personalized approaches to active immunotherapy in cancer
Ophir Eran, Bobisse Sara, Coukos George, Harari Alexandre, Kandalaft Lana E., 2016/01. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1865 (1) pp. 72-82. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_01C8158A4FDC]
 
Phage antibody display libraries: a powerful antibody discovery platform for immunotherapy.
Zhao A., Tohidkia M.R., Siegel D.L., Coukos G., Omidi Y., 2016. Critical Reviews In Biotechnology, 36 (2) pp. 276-289. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_025704A90C14]
Phage Selection of Peptide Macrocycles against β-Catenin To Interfere with Wnt Signaling.
Bertoldo D., Khan M.M., Dessen P., Held W., Huelsken J., Heinis C., 2016. Chemmedchem, 11 (8) pp. 834-839. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A9DB2F23A326]
 
Principes de la thérapie cellulaire par transfert adoptif à base de Tumor Infiltrating Lymphocytes [Principles of adoptive cell therapy based on "Tumor Infiltrating Lymphocytes"].
Martins F., Orcurto A., Michielin O., Coukos G., 2016. Revue Médicale Suisse, 12 (519) pp. 989-993. Peer-reviewed.
[Pmid][serval:BIB_4503E564FA67]
 
Regulatory circuits of T cell function in cancer.
Speiser D.E., Ho P.C., Verdeil G., 2016. Nature Reviews. Immunology, 16 (10) pp. 599-611. Peer-reviewed.
[DOI][Pmid][serval:BIB_8F2CE0F06A85]
Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.
Kerr B.A., West X.Z., Kim Y.W., Zhao Y., Tischenko M., Cull R.M., Phares T.W., Peng X.D., Bernier-Latmani J., Petrova T.V. et al., 2016. Nature Communications, 7 p. 10960. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AF9B9DA21B6D]
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.
Rota G., Ludigs K., Siegert S., Tardivel A., Morgado L., Reith W., De Gassart A., Guarda G., 2016. Journal of Immunology, 196 (7) pp. 2939-2946.
[URN][DOI][WoS][Pmid][serval:BIB_385A42D5B31A]
The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation.
Kivelä R., Salmela I., Nguyen Y.H., Petrova T.V., Koistinen H.A., Wiener Z., Alitalo K., 2016. Nature Communications, 7 p. 13124. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_216872926482]
 
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.
Quail D.F., Bowman R.L., Akkari L., Quick M.L., Schuhmacher A.J., Huse J.T., Holland E.C., Sutton J.C., Joyce J.A., 2016. Science, 352 (6288) pp. aad3018. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F2EFF73DAC5C]
TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer.
Bron S., Henry L., Faes-Van't Hull E., Turrini R., Vanhecke D., Guex N., Ifticene-Treboux A., Marina Iancu E., Semilietof A., Rufer N. et al., 2016. Oncoimmunology, 5 (2) pp. e1073882. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4C97ACD28497]
Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells.
Korniotis S., Gras C., Letscher H., Montandon R., Mégret J., Siegert S., Ezine S., Fallon P.G., Luther S.A., Fillatreau S. et al., 2016. Nature Communications, 7 p. 12134.
[URN][DOI][WoS][Pmid][serval:BIB_7B6062861BAB]
 
Unsupervised HLA Peptidome Deconvolution Improves Ligand Prediction Accuracy and Predicts Cooperative Effects in Peptide-HLA Interactions.
Bassani-Sternberg M., Gfeller D., 2016. Journal of Immunology (baltimore, Md. : 1950), 197 (6) pp. 2492-2499. Peer-reviewed.
[DOI][Pmid][serval:BIB_7C66F6F02EE5]
Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8(+) and CD4(+) T-cell responses with multiple specificities including a novel DR7-restricted epitope.
Baumgaertner P., Costa Nunes C., Cachot A., Maby-El Hajjami H., Cagnon L., Braun M., Derré L., Rivals J.P., Rimoldi D., Gnjatic S. et al., 2016. Oncoimmunology, 5 (10) pp. e1216290. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_A6A68301DF3E]
Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients.
Murray T., Fuertes Marraco S.A., Baumgaertner P., Bordry N., Cagnon L., Donda A., Romero P., Verdeil G., Speiser D.E., 2016. Frontiers in immunology, 7 p. 573. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_65B45F9B7588]
2015
 
Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Olesen R., Vigano S., Rasmussen T.A., Søgaard O.S., Ouyang Z., Buzon M., Bashirova A., Carrington M., Palmer S., Brinkmann C.R. et al., 2015/10. Journal of virology, 89 (20) pp. 10176-10189. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88943194E009]
 
Immuno-Oncology
Michielin Olivier, Coukos George, 2015/09/09. Progress in Tumor Research, 42, S. Karger AG.
[DOI][serval:BIB_3BABB0481053]
 
Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties.
Vigano S., Negron J., Ouyang Z., Rosenberg E.S., Walker B.D., Lichterfeld M., Yu X.G., 2015/08. Journal of virology, 89 (15) pp. 7829-7840. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_96BD94D591B4]
29 th Annual meeting of the Society for Immunotherapy of Cancer (SITC)
Hurwitz A.A., Lee S., Knox S., Kohrt H., Verdeil G., Romano E., Margolin K., Urba W.J., Speiser D.E., 2015. Journal For Immunotherapy of Cancer, 3 p. 0.
[URN][DOI][WoS][serval:BIB_A9D9EDBBD5B8]
 
A01: Associations of lymphangiogenesis with immune profiles of melanoma patients
Bordry N., Gannon P., Foukas P., Letovanec I., Meyer C., Legat A., Yan P., Romano E., Swartz M., Speiser D., 2015. pp. - dans AACR Special Conference on Cellular Heterogeneity in the Tumor Microenvironment, Cancer Research. Peer-reviewed.
[DOI][WoS][serval:BIB_65E43B4F02BD]
 
An infrared spectral signature of human lymphocyte subpopulations from peripheral blood.
Wald N., Legat A., Meyer C., Speiser D.E., Goormaghtigh E., 2015. Analyst, 140 (7) pp. 2257-2265. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4923CFD2F1E9]
 
An ultra-sensitive impedimetric immunosensor for detection of the serum oncomarker CA-125 in ovarian cancer patients.
Johari-Ahar M., Rashidi M.R., Barar J., Aghaie M., Mohammadnejad D., Ramazani A., Karami P., Coukos G., Omidi Y., 2015. Nanoscale, 7 (8) pp. 3768-3779. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A3D5DD2E8958]
BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.
Moor A.E., Anderle P., Cantù C., Rodriguez P., Wiedemann N., Baruthio F., Deka J., André S., Valenta T., Moor M.B. et al., 2015. Ebiomedicine, 2 (12) pp. 1932-1943. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CF71D7FE666E]
CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis.
Trabanelli S., Curti A., Lecciso M., Salomé B., Riether C., Ochsenbein A., Romero P., Jandus C., 2015. Haematologica, 100 (7) pp. e257-e260. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6540145553D7]
Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.
Liebl J., Zhang S., Moser M., Agalarov Y., Demir C.S., Hager B., Bibb J.A., Adams R.H., Kiefer F., Miura N. et al., 2015. Nature Communications, 6 p. 7274. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3B60F81231F4]
Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma.
Kurscheid S., Bady P., Sciuscio D., Samarzija I., Shay T., Vassallo I., Criekinge W.V., Daniel R.T., van den Bent M.J., Marosi C. et al., 2015. Genome Biology, 16 (1) p. 16. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B14A6FAA52B1]
 
Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group.
Hingorani P., Missiaglia E., Shipley J., Anderson J.R., Triche T.J., Delorenzi M., Gastier-Foster J., Wing M., Hawkins D.S., Skapek S.X., 2015. Clinical Cancer Research, 21 (20) pp. 4733-4739. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F32C8231A153]
Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?
Apetoh L., Ladoire S., Coukos G., Ghiringhelli F., 2015. Annals of Oncology, 26 (9) pp. 1813-1823. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B0FEEA6CE1BB]
 
Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.
Yan X., Hu Z., Feng Y., Hu X., Yuan J., Zhao S.D., Zhang Y., Yang L., Shan W., He Q. et al., 2015. Cancer Cell, 28 (4) pp. 529-540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C1048CB1FB57]
 
Consensus nomenclature for CD8 + T cell phenotypes in cancer
Apetoh L., Smyth M.J., Drake C.G., Abastado J.P., Apte R.N., Ayyoub M., Blay J.Y., Bonneville M., Butterfield L.H., Caignard A. et al., 2015. Oncoimmunology, 4 (4) pp. e998538. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D1DB47249851]
 
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response.
Olson O.C., Joyce J.A., 2015. Nature Reviews. Cancer, 15 (12) pp. 712-729. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CED987E8D926]
DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.
Bernier-Latmani J., Cisarovsky C., Demir C.S., Bruand M., Jaquet M., Davanture S., Ragusa S., Siegert S., Dormond O., Benedito R. et al., 2015. Journal of Clinical Investigation, 2015 pp. 4572-4586. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BA1CB6D590A9]
 
Erratum to: Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells.
Barar J., Kafil V., Majd M.H., Barzegari A., Khani S., Johari-Ahar M., Asgari D., Coukos G., Omidi Y., 2015..
[DOI][WoS][Pmid][serval:BIB_070748C72E26]
FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature.
Sabine A., Bovay E., Demir C.S., Kimura W., Jaquet M., Agalarov Y., Zangger N., Scallan J.P., Graber W., Gulpinar E. et al., 2015. Journal of Clinical Investigation, 125 (10) pp. 3861-3877. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EAA65C411B89]
Future perspectives in melanoma research: meeting report from the "Melanoma Bridge";: Napoli, December 3rd-6th 2014.
Ascierto P.A., Atkins M., Bifulco C., Botti G., Cochran A., Davies M., Demaria S., Dummer R., Ferrone S., Formenti S. et al., 2015. Journal of Translational Medicine, 13 p. 374. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D7403A104D4B]
GATA2 is required for lymphatic vessel valve development and maintenance.
Kazenwadel J., Betterman K.L., Chong C.E., Stokes P.H., Lee Y.K., Secker G.A., Agalarov Y., Demir C.S., Lawrence D.M., Sutton D.L. et al., 2015. Journal of Clinical Investigation, 125 (8) pp. 2979-2994. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7CE1E8B0E0BD]
Genome-wide RNA profiling of long-lasting stem cell-like memory CD8 T cells induced by Yellow Fever vaccination in humans.
Fuertes Marraco S.A., Soneson C., Delorenzi M., Speiser D.E., 2015. Genomics Data, 5 pp. 297-301. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C2352A0D8CCA]
 
High-throughput monitoring of human tumor-specific T-cell responses with large peptide pools.
Chevalier M.F., Bobisse S., Costa-Nunes C., Cesson V., Jichlinski P., Speiser D.E., Harari A., Coukos G., Romero P., Nardelli-Haefliger D. et al., 2015. Oncoimmunology, 4 (10) pp. e1029702. Peer-reviewed.
[DOI][Pmid][serval:BIB_FC441F50334F]
Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.
Hebeisen M., Schmidt J., Guillaume P., Baumgaertner P., Speiser D.E., Luescher I., Rufer N., 2015. Cancer Research, 75 (10) pp. 1983-1991. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_502682EFE89B]
Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens.
Hebeisen M., Allard M., Gannon P.O., Schmidt J., Speiser D.E., Rufer N., 2015. Frontiers in Immunology, 6 p. 582. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B225879082EC]
Inhibitory Receptors Beyond T Cell Exhaustion.
Fuertes Marraco S.A., Neubert N.J., Verdeil G., Speiser D.E., 2015. Frontiers in Immunology, 6 p. 310. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BC63AADBECC]
Introducing the clinical trials monitor: a new section of the journal for immunotherapy of cancer.
Emens L.A., Romero P., 2015. Journal for Immunotherapy of Cancer, 3 p. 49.
[URN][DOI][WoS][Pmid][serval:BIB_F893A483668A]
 
Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients.
Romano E., Kusio-Kobialka M., Foukas P.G., Baumgaertner P., Meyer C., Ballabeni P., Michielin O., Weide B., Romero P., Speiser D.E., 2015. Proceedings of the National Academy of Sciences of the United States of America, 112 (19) pp. 6140-6145.
[DOI][WoS][Pmid][serval:BIB_D1CB1536043B]
 
Isolation and Validation of Anti-B7-H4 scFvs from an Ovarian Cancer scFv Yeast-Display Library.
Dangaj D., Scholler N., 2015. Methods In Molecular Biology, 1319 pp. 37-49. Peer-reviewed.
[DOI][Pmid][serval:BIB_002FBB72C992]
JITC launches a new section: commentary and editorials.
Capitini C.M., Romero P., 2015. Journal For Immunotherapy of Cancer, 3 p. 28. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_9A199CEFB765]
Local Salmonella immunostimulation recruits vaccine-specific CD8 T cells and increases regression of bladder tumor.
Domingos-Pereira S., Hojeij R., Reggi E., Derré L., Chevalier M.F., Romero P., Jichlinski P., Nardelli-Haefliger D., 2015. Oncoimmunology, 4 (7) pp. e1016697. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4AEADA8DF103]
Long-lasting stem cell-like memory CD8+ T cells with a naïve-like profile upon yellow fever vaccination.
Fuertes Marraco S.A., Soneson C., Cagnon L., Gannon P.O., Allard M., Maillard S.A., Montandon N., Rufer N., Waldvogel S., Delorenzi M. et al., 2015. Science Translational Medicine, 7 (282) pp. 282ra48. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_44DEAD18C07E]
 
MAF drives CD8(+) T-cell exhaustion
Verdeil G., 2015. Oncoimmunology, 5 (2) pp. e1082707.
[DOI][WoS][Pmid][serval:BIB_AC22A2B8C845]
 
Meet me in the middle: dual origins of dermal lymphatic vasculature in mammals
Bernier-Latmani J., Sabine A., Petrova T.V., 2015. Circulation Research, 116 (10) pp. 1630-1632. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38244BE2172A]
 
Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.
Giordano M., Henin C., Maurizio J., Imbratta C., Bourdely P., Buferne M., Baitsch L., Vanhille L., Sieweke M.H., Speiser D.E. et al., 2015. EMBO Journal, 34 (15) pp. 2042-2058. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C3675CA7C520]
Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells.
Barar J., Kafil V., Majd M.H., Barzegari A., Khani S., Johari-Ahar M., Asgari D., Coukos G., Omidi Y., 2015. Journal of Nanobiotechnology, 13 (1) p. 26. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D3C3F085EE13]
Overexpression of GPC6 and TMEM132D in Early Stage Ovarian Cancer Correlates with CD8+ T-Lymphocyte Infiltration and Increased Patient Survival.
Karapetsas A., Giannakakis A., Dangaj D., Lanitis E., Kynigopoulos S., Lambropoulou M., Tanyi J.L., Galanis A., Kakolyris S., Trypsianis G. et al., 2015. Biomed Research International, 2015 p. 712438. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_082FCA6C4652]
 
Potential approaches for more successful dendritic cell-based immunotherapy.
Chiang C.L., Balint K., Coukos G., Kandalaft L.E., 2015. Expert Opinion On Biological Therapy, 15 (4) pp. 569-582. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_05E27D099B4D]
 
Pregnancy after breast cancer: Are young patients willing to participate in clinical studies?
Pagani O., Ruggeri M., Manunta S., Saunders C., Peccatori F., Cardoso F., Kaufman B., Paluch-Shimon S., Gewefel H., Gallerani E. et al., 2015. Breast, 24 (3) pp. 201-207. Peer-reviewed.
[DOI][Pmid][serval:BIB_530C97E722B3]
Prognosis of stage II and III colon cancer treated with adjuvant 5-fluorouracil or FOLFIRI in relation to microsatellite status: results of the PETACC-3 trial?.
Klingbiel D., Saridaki Z., Roth A.D., Bosman F.T., Delorenzi M., Tejpar S., 2015. Annals of Oncology, 26 (1) pp. 126-132. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_46137476568A]
 
Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence.
Gannon P.O., Wieckowski S., Baumgaertner P., Hebeisen M., Allard M., Speiser D.E., Rufer N., 2015. Journal of Immunology, 195 (1) pp. 356-366. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DE2F9C9EC3C3]
 
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.
Bowtell D.D., Böhm S., Ahmed A.A., Aspuria P.J., Bast R.C., Beral V., Berek J.S., Birrer M.J., Blagden S., Bookman M.A. et al., 2015. Nature Reviews. Cancer, 15 (11) pp. 668-679. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DD8901DF61B3]
 
Shear stress-induced atherosclerotic plaque composition in ApoE(-/-) mice is modulated by connexin37
Pfenniger A., Meens M.J., Pedrigi R.M., Foglia B., Sutter E., Pelli G., Rochemont V., Petrova T.V., Krams R., Kwak B.R., 2015. Atherosclerosis, 243 (1) pp. 1-10. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2AF1EC03E581]
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
Demaria O., De Gassart A., Coso S., Gestermann N., Di Domizio J., Flatz L., Gaide O., Michielin O., Hwu P., Petrova T.V. et al., 2015. Proceedings of the National Academy of Sciences of the United States of America, 112 (50) pp. 15408-15413.
[URN][DOI][WoS][Pmid][serval:BIB_572BDFE9D6A6]
T Cells Bearing a Chimeric Antigen Receptor against Prostate-Specific Membrane Antigen Mediate Vascular Disruption and Result in Tumor Regression.
Santoro S.P., Kim S., Motz G.T., Alatzoglou D., Li C., Irving M., Powell D.J., Coukos G., 2015. Cancer Immunology Research, 3 (1) pp. 68-84. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_00550F80C313]
 
Targeting Programmed Cell Death 1 in Ovarian Cancer.
Homicsko K., Coukos G., 2015. Journal of Clinical Oncology, 33 (34) pp. 3987-3989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A88FF3F32E5C]
Targeting the tumor vasculature to enhance T cell activity.
Lanitis E., Irving M., Coukos G., 2015. Current Opinion in Immunology, 33 pp. 55-63. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_266C11B75B8F]
Targeting the undruggable: immunotherapy meets personalized oncology in the genomic era.
Martin S.D., Coukos G., Holt R.A., Nelson B.H., 2015. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo, 26 (12) pp. 2367-2374. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_044E24F585FB]
The consensus molecular subtypes of colorectal cancer.
Guinney J., Dienstmann R., Wang X., de Reyniès A., Schlicker A., Soneson C., Marisa L., Roepman P., Nyamundanda G., Angelino P. et al., 2015. Nature Medicine, 21 (11) pp. 1350-1356. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6206DC2BFE0E]
The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy.
Zsiros E., Duttagupta P., Dangaj D., Li H., Frank R., Garrabrant T., Hagemann I.S., Levine B.L., June C.H., Zhang L. et al., 2015. Clinical Cancer Research, 21 (12) pp. 2840-2850. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_87A4CCCAC4DE]
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