Centre intégratif de génomique

Equipe principale | CIG Services communs | Groupe Benton | Groupe Fajas | Groupe Fankhauser | Groupe Franken | Groupe Gambetta | Groupe Gatfield | Groupe Larsch | Groupe Michalik | Groupe Reymond | Groupe Roignant | Groupe van Leeuwen | Groupe Vastenhouw | Groupe Vjestica | Plateforme de biostatistique | Plateforme Genomics Technologies Facility (GTF) | Plateforme Protein Analysis Facility (PAF)
Publications | Mémoires et thèses

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1739 publications

... | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1997 | 1994 |
2006
EGASP: the human ENCODE Genome Annotation Assessment Project.
Guigó R., Flicek P., Abril J.F., Reymond A., Lagarde J., Denoeud F., Antonarakis S., Ashburner M., Bajic V.B., Birney E. et al., 2006. Genome Biology, 7 Suppl 1 pp. S2.1-S231. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9B8BEDF24C37]
 
Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding.
Bady I., Marty N., Dallaporta M., Emery M., Gyger J., Tarussio D., Foretz M., Thorens B., 2006. Diabetes, 55 (4) pp. 988-995. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_58B1E0A07305]
 
Evolutionary fate of retroposed gene copies in the human genome.
Vinckenbosch N., Dupanloup I., Kaessmann H., 2006. Proceedings of the National Academy of Sciences of the United States of America, 103 (9) pp. 3220-3225. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D954A7EBB2FF]
Evolutionary simulations to detect functional lineage-specific genes.
Dupanloup I., Kaessmann H., 2006. Bioinformatics, 22 (15) pp. 1815-1822. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_43D3835CBB98]
 
From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.
Feige J.N., Gelman L., Michalik L., Desvergne B., Wahli W., 2006. Progress in Lipid Research, 45 (2) pp. 120-159. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3E4720DEC9E3]
 
Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis.
Icre G., Wahli W., Michalik L., 2006. Journal of Investigative Dermatology, 11 (1) pp. 30-35. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E954323AA321]
GENCODE: producing a reference annotation for ENCODE.
Harrow J., Denoeud F., Frankish A., Reymond A., Chen C.K., Chrast J., Lagarde J., Gilbert J.G., Storey R., Swarbreck D. et al., 2006. Genome Biology, 7 Suppl 1 pp. S4.1-S4.9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F594806247A7]
 
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function.
Membrez M., Hummler E., Beermann F., Haefliger J.A., Savioz R., Pedrazzini T., Thorens B., 2006. Molecular and Cellular Biology, 26 (11) pp. 4268-4276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_762B2B505DC8]
 
Glycogen content in the cerebral cortex increases with sleep loss in C57BL/6J mice.
Franken P., Gip P., Hagiwara G., Ruby N.F., Heller H.C., 2006. Neuroscience Letters, 402 (1-2) pp. 176-179. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8BF0AEE24C5B]
Integrating nuclear receptor mobility in models of gene regulation.
Gelman L., Feige J.N., Tudor C., Engelborghs Y., Wahli W., Desvergne B., 2006. Nuclear Receptor Signaling, 4 pp. e010. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_D4A7B68B53C5]
 
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.
Michalik L., Auwerx J., Berger J.P., Chatterjee V.K., Glass C.K., Gonzalez F.J., Grimaldi P.A., Kadowaki T., Lazar M.A., O'Rahilly S. et al., 2006. Pharmacological Reviews, 58 (4) pp. 726-741. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DB7E15D7FA7D]
 
Involvement of PPAR nuclear receptors in tissue injury and wound repair.
Michalik L., Wahli W., 2006. Journal of Clinical Investigation, 116 (3) pp. 598-606. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2E99655B9A39]
 
L'axe entéro-insulaire: rôle de l'intestin et régulation glycémique
Thorens B., 2006. Journées annuelles de diabétologie de l'Hôtel-Dieu pp. 67-73.
[Pmid][serval:BIB_3B10E99E3EA0]
 
Let there be light in the nucleus!
Lorrain S., Genoud T., Fankhauser C., 2006. Current Opinion in Plant Biology, 9 (5) pp. 509-514.
[DOI][WoS][Pmid][serval:BIB_701939132B4D]
Maf1, a new player in the regulation of human RNA polymerase III transcription.
Reina J.H., Azzouz T.N., Hernandez N., 2006. PLoS ONE, 1 pp. e134. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FC2177747AE6]
 
Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells.
Tweedie E., Artner I., Crawford L., Poffenberger G., Thorens B., Stein R., Powers A.C., Gannon M., 2006. Diabetes, 55 (12) pp. 3264-3270. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_17F1B0E4FB6D]
 
Molecular genetics and treatment of narcolepsy.
Dauvilliers Y., Tafti M., 2006. Annals of Medicine, 38 (4) pp. 252-262. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B394BAC3B683]
mtDB: Human Mitochondrial Genome Database, a resource for population genetics and medical sciences
Ingman M., Gyllensten U., 2006. Nucleic Acids Research, 34 (Database issue) pp. D749-D751.
[URN][DOI][WoS][Pmid][serval:BIB_9D7629A62E8C]
 
NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions.
Franken P., Dudley C.A., Estill S.J., Barakat M., Thomason R., O'Hara B.F., McKnight S.L., 2006. Proceedings of the National Academy of Sciences of the United States of America, 103 (18) pp. 7118-7123.
[DOI][WoS][Pmid][serval:BIB_A6C0B2724814]
 
On the ORigin of smell: odorant receptors in insects.
Benton R., 2006. Cellular and Molecular Life Sciences, 63 (14) pp. 1579-1585. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_258D873241BF]
Patterns of evolution of host proteins involved in retroviral pathogenesis.
Ortiz M., Bleiber G., Martinez R., Kaessmann H., Telenti A., 2006. Retrovirology, 3 p. 11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4FD872F6B0FD]
 
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.
Knauf C., Rieusset J., Foretz M., Cani P.D., Uldry M., Hosokawa M., Martinez E., Bringart M., Waget A., Kersten S. et al., 2006. Endocrinology, 147 (9) pp. 4067-4078. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4BF6D6D4BC30]
 
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetes.
Schuler M., Ali F., Chambon C., Duteil D., Bornert J.M., Tardivel A., Desvergne B., Wahli W., Chambon P., Metzger D., 2006. Cell Metabolism, 4 (5) pp. 407-414. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1204C55A287D]
 
Physiological ligands of PPARs in inflammation and lipid homeostasis
Lathion C., Michalik L., Wahli W., 2006. Future Lipidology, 1 (2) pp. 191-201. Peer-reviewed.
[DOI][WoS][serval:BIB_D78B39FC9AC1]
 
PHYTOCHROME KINASE SUBSTRATE 1 is a phototropin 1 binding protein required for phototropism.
Lariguet P., Schepens I., Hodgson D., Pedmale U.V., Trevisan M., Kami C., de Carbonnel M., Alonso J.M., Ecker J.R., Liscum E. et al., 2006. Proceedings of the National Academy of Sciences of the United States of America, 103 (26) pp. 10134-10139. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_53642A057EBB]
PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway
Varnat F., Desvergne B., 2006. Gastroenterology, 131 (5) pp. 1658-1659. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_320E3E303DDD]
 
PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway.
Varnat F., Heggeler B.B., Grisel P., Boucard N., Corthésy-Theulaz I., Wahli W., Desvergne B., 2006. Gastroenterology, 131 (2) pp. 538-553. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A0BE8C5A5A8B]
 
PPARs and colon cancers : A curse or a cure ?
Michalik L., Wahli W., 2006. pp. 145-161 dans Bamba H., Ota S. (eds.) Recent Advances in Gastrointestinal Carcinogenesis, Transworld Research Network.
[serval:BIB_54E54C9A2F24]
 
PPARs in fetal and early postnatal development
Rotman N., Michalik L., Desvergne B., Wahli W., 2006. pp. 33-64 dans Tanejah R. (eds.) Nuclear receptors in development chap. 2, Elsevier.
[DOI][serval:BIB_8ADDDF0F2198]
 
PPARs: lipid sensors that regulate cell differentiation processes
Varnat F., Michalik L., Desvergne B., Wahli W., 2006. pp. 117-131 dans Brigelius-Flohé R., Joost H.G. (eds.) Nutritional genomics : impact on health and disease chap. 7, Wiley-VCH.
[DOI][serval:BIB_03A1DD7A70C4]
 
Quand les plantes sortent de l'ombre
Fankhauser C., Lorrain S., 2006. Pour la science 349 pp. 68-73.
[serval:BIB_5D241DCB6651]
Rapid accumulation of trihydroxy oxylipins and resistance to the bean rust pathogen Uromyces fabae following wounding in Vicia faba
Walters D.R., Cowley T., Weber H., 2006. Annals of Botany, 97 (5) pp. 779-784.
[URN][DOI][WoS][Pmid][serval:BIB_D2203E12863D]
 
Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.
Canaple L., Rambaud J., Dkhissi-Benyahya O., Rayet B., Tan N.S., Michalik L., Delaunay F., Wahli W., Laudet V., 2006. Molecular Endocrinology, 20 (8) pp. 1715-1727. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38FABE02C7C5]
 
Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts.
Ali F.Y., Egan K., FitzGerald G.A., Desvergne B., Wahli W., Bishop-Bailey D., Warner T.D., Mitchell J.A., 2006. American Journal of Respiratory Cell and Molecular Biology, 34 (2) pp. 242-246. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3564A8DE2B4E]
 
Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions.
Baumann C.R., Kilic E., Petit B., Werth E., Hermann D.M., Tafti M., Bassetti C.L., 2006. Sleep, 29 (10) pp. 1339-1344. Peer-reviewed.
[WoS][Pmid][serval:BIB_19BB826015A0]
 
Submicroscopic deletion in patients with Williams-Beuren syndrome influences expression levels of the nonhemizygous flanking genes.
Merla G., Howald C., Henrichsen C.N., Lyle R., Wyss C., Zabot M.T., Antonarakis S.E., Reymond A., 2006. American Journal of Human Genetics, 79 (2) pp. 332-341. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A78B3DE949B3]
 
Tandem chimerism as a means to increase protein complexity in the human genome.
Parra G., Reymond A., Dabbouseh N., Dermitzakis E.T., Castelo R., Thomson T.M., Antonarakis S.E., Guigó R., 2006. Genome Research, 16 (1) pp. 37-44.
[DOI][WoS][Pmid][serval:BIB_E801FA5E75F1]
 
Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation.
Mathe Z., Dupraz P., Rinsch C., Thorens B., Bosco D., Zbinden M., Morel P., Berney T., Pepper M.S., 2006. Cell Transplantation, 15 (7) pp. 621-636. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_76B961622F68]
 
The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity.
Mandard S., Zandbergen F., van Straten E., Wahli W., Kuipers F., Müller M., Kersten S., 2006. Journal of Biological Chemistry, 281 (2) pp. 934-944. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B7E703C1DB38]
The future is genome-wide.
Deutsch S., Reymond A., 2006. Genome Biology, 7 (8) p. 324.
[URN][DOI][WoS][Pmid][serval:BIB_4689B3FAB725]
 
Transcriptional regulation of metabolism.
Desvergne B., Michalik L., Wahli W., 2006. Physiological Reviews, 86 (2) pp. 465-514. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6C4B9B47E043]
 
Two high throughput technologies to detect segmental aneuploidies identify new Williams-Beuren syndrome patients with atypical deletions.
Howald C., Merla G., Digilio M.C., Amenta S., Lyle R., Deutsch S., Choudhury U., Bottani A., Antonarakis S.E., Fryssira H. et al., 2006. Journal of Medical Genetics, 43 (3) pp. 266-273. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AE9A3A0EBEFA]
2005
 
RACE: Remote Analysis Computation for gene Expression data
Psarros M., Heber S., Sick M., Thoppae G., Harshman K., Sick B., 2005/07. Nucleic Acids Research, 33 (Web Server issue) pp. W638-43.
[DOI][WoS][Pmid][serval:BIB_16958AE0783D]
 
A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein.
Wattenhofer M., Sahin-Calapoglu N., Andreasen D., Kalay E., Caylan R., Braillard B., Fowler-Jaeger N., Reymond A., Rossier B.C., Karaguzel A. et al., 2005. Human Genetics, 117 (6) pp. 528-535. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FFEE7EE86CAA]
 
Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1.
Kim Y.S., Kim J.M., Jung D.L., Kang J.E., Lee S., Kim J.S., Seol W., Shin H.C., Kwon H.S., Van Lint C. et al., 2005. Journal of Biological Chemistry, 280 (22) pp. 21545-21552. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A6392E665579]
 
bHLH class transcription factors take centre stage in phytochrome signalling.
Duek P.D., Fankhauser C., 2005. Trends in Plant Science, 10 (2) pp. 51-54. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C192FDCEEB0F]
Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes.
Castelo R., Reymond A., Wyss C., Câmara F., Parra G., Antonarakis S.E., Guigó R., Eyras E., 2005. Nucleic Acids Research, 33 (6) pp. 1935-1939.
[URN][DOI][WoS][Pmid][serval:BIB_969A35C25E60]
 
Conserved non-genic sequences - an unexpected feature of mammalian genomes.
Dermitzakis E.T., Reymond A., Antonarakis S.E., 2005. Nature Reviews. Genetics, 6 (2) pp. 151-157. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_25C9FD53BD1D]
 
Decreased expression of peroxisome proliferator-activated receptor alpha and liver fatty acid binding protein after partial hepatectomy of rats and mice.
Skrtic S., Carlsson L., Ljungberg A., Lindén D., Michalik L., Wahli W., Oscarsson J., 2005. Liver International, 25 (1) pp. 33-40. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_304DA45FAE9E]
 
Dosage-dependent effects of Akt1/protein kinase Balpha (PKBalpha) and Akt3/PKBgamma on thymus, skin, and cardiovascular and nervous system development in mice.
Yang Z.Z., Tschopp O., Di-Poï N., Bruder E., Baudry A., Dümmler B., Wahli W., Hemmings B.A., 2005. Molecular and Cellular Biology, 25 (23) pp. 10407-10418. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8DC81DF45098]
Emergence of young human genes after a burst of retroposition in primates.
Marques A.C., Dupanloup I., Vinckenbosch N., Reymond A., Kaessmann H., 2005. Plos Biology, 3 (11) pp. e357. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_42F38774BBD8]
 
EMPReSS: standardised phenotype screens for functional annotation of the mouse genome
Eumorphia_Consortium, Wahli W., Delgado MB., Desvergne B., Michalik L., Bedu E., 2005. Nature Genetics, 37 (11) p. 1155. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_344727663BB3]
 
Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.
Di-Poï N., Ng C.Y., Tan N.S., Yang Z., Hemmings B.A., Desvergne B., Michalik L., Wahli W., 2005. Molecular and Cellular Biology, 25 (5) pp. 1696-1712. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E17C3B93B35B]
Evolutionary comparison provides evidence for pathogenicity of RMRP mutations.
Bonafé L., Dermitzakis E.T., Unger S., Greenberg C.R., Campos-Xavier B.A., Zankl A., Ucla C., Antonarakis S.E., Superti-Furga A., Reymond A., 2005. Plos Genetics, 1 (4) pp. e47. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CC6ABC66BB92]
 
Fluorescence imaging reveals the nuclear behavior of peroxisome proliferator-activated receptor/retinoid X receptor heterodimers in the absence and presence of ligand.
Feige J.N., Gelman L., Tudor C., Engelborghs Y., Wahli W., Desvergne B., 2005. Journal of Biological Chemistry, 280 (18) pp. 17880-17890. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_312147D3381D]
 
Functional role of RXRs and PPARgamma in mature adipocytes.
Metzger D., Imai T., Jiang M., Takukawa R., Desvergne B., Wahli W., Chambon P., 2005. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 73 (1) pp. 51-58. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9AAC145A821E]
Gene finding in the chicken genome.
Eyras E., Reymond A., Castelo R., Bye J.M., Camara F., Flicek P., Huckle E.J., Parra G., Shteynberg D.D., Wyss C. et al., 2005. BMC Bioinformatics, 6 p. 131. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_35142]
 
Genes for normal sleep and sleep disorders.
Tafti M., Maret S., Dauvilliers Y., 2005. Annals of Medicine, 37 (8) pp. 580-589. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4E458DBA1640]
 
Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.
Tan N.S., Michalik L., Desvergne B., Wahli W., 2005. Journal of Biological Chemistry, 280 (18) pp. 18163-18170. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_09ECDADC8AB9]
Genetics of narcolepsy and other major sleep disorders.
Maret S., Tafti M., 2005. Swiss Medical Weekly, 135 (45-46) pp. 662-665.
[URN][WoS][Pmid][serval:BIB_48E586F6C6E1]
 
Genetics of normal and pathological sleep in humans.
Dauvilliers Y., Maret S., Tafti M., 2005. Sleep Medicine Reviews, 9 (2) pp. 91-100. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9E6BC9DD9162]
 
How pathogenic is the p.D104N/endostatin polymorphic allele of COL18A1 in Knobloch syndrome? Reply
Antonarakis SE, Reymond A, Menzel O, Bekkeheien RC, Fukai N, Boye E, Kosztolanyi G, Aftimos S, Deutsch S, Scott HS et al., 2005. Human Mutation, 25 (3) pp. 316-316.
[DOI][WoS][serval:BIB_35138]
 
Identification of cancer/testis-antigen genes by massively parallel signature sequencing.
Chen Y.T., Scanlan M.J., Venditti C.A., Chua R., Theiler G., Stevenson B.J., Iseli C., Gure A.O., Vasicek T., Strausberg R.L. et al., 2005. Proceedings of the National Academy of Sciences of the United States of America, 102 (22) pp. 7940-7945. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F162E516267A]
 
Interaction of sleep homeostasis and circadian rhythmicity : dependent or independent systems?
Dijk D.J., Franken P., 2005. pp. 418-434 dans Kryger M.H., Roth T, Dement W.C. (eds.) Interaction of Sleep Homeostasis and Circadian Rhythmicity: Dependent or Independent Systems? chap. 34, Saunders.
[serval:BIB_26B2B51F10FB]
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.
Rousseaux C., Lefebvre B., Dubuquoy L., Lefebvre P., Romano O., Auwerx J., Metzger D., Wahli W., Desvergne B., Naccari G.C. et al., 2005. Journal of Experimental Medicine, 201 (8) pp. 1205-1215. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A550C6096450]
 
Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.
Gelman L., Michalik L., Desvergne B., Wahli W., 2005. Current Opinion in Cell Biology, 17 (2) pp. 216-222. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B8BBADFB7D53]
 
Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice.
Xie X., Dumas T., Tang L., Brennan T., Reeder T., Thomas W., Klein R.D., Flores J., O'Hara B.F., Heller H.C. et al., 2005. Brain Research, 1052 (2) pp. 212-221. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D1788157402D]
 
Microsomal triglyceride transfer protein promotes the secretion of Xenopus laevis vitellogenin A1.
Sellers J.A., Hou L., Schoenberg D.R., Batistuzzo de Medeiros S.R., Wahli W., Shelness G.S., 2005. Journal of Biological Chemistry, 280 (14) pp. 13902-13905. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_855D61E25B07]
 
Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.
Tan N.S., Michalik L., Desvergne B., Wahli W., 2005. Journal of Steroid Biochemistry and Molecular Biology, 93 (2-5) pp. 99-105. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_14A08914D33D]
Mutational analysis of BTAF1-TBP interaction: BTAF1 can rescue DNA-binding defective TBP mutants.
Klejman M.P., Zhao X., van Schaik F.M., Herr W., Timmers H.T., 2005. Nucleic acids research, 33 (17) pp. 5426-5436. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_414353841D38]
 
Nuclear accumulation of the phytochrome A photoreceptor requires FHY1.
Hiltbrunner A., Viczián A., Bury E., Tscheuschler A., Kircher S., Tóth R., Honsberger A., Nagy F., Fankhauser C., Schäfer E., 2005. Current Biology, 15 (23) pp. 2125-2130. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6035803B4B0A]
 
Nutrigenomics and nutrigenetics: the emerging faces of nutrition.
Mutch D.M., Wahli W., Williamson G., 2005. FASEB journal, 19 (12) pp. 1602-1616. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DE84653D432A]
 
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.
Gremlich S., Nolan C., Roduit R., Burcelin R., Peyot M.L., Delghingaro-Augusto V., Desvergne B., Michalik L., Prentki M., Wahli W., 2005. Endocrinology, 146 (1) pp. 375-382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA00C2E702BB]
 
Peroxisome proliferator activated receptors
Genolet R., Michalik L., Wahli W., 2005. pp. 267-280 dans Dufour J.F., Clavien P.A., Trautwein C., Graf R. (eds.) Signaling pathways in liver diseases, Springer.
[serval:BIB_4496A38F14EF]
Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes.
Planavila A., Rodríguez-Calvo R., Jové M., Michalik L., Wahli W., Laguna J.C., Vázquez-Carrera M., 2005. Cardiovascular Research, 65 (4) pp. 832-841. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EBA9B8610022]
 
Peroxisome proliferator-activated receptor beta/delta as a therapeutic target for metabolic diseases.
Bedu E., Wahli W., Desvergne B., 2005. Expert Opinion On Therapeutic Targets, 9 (4) pp. 861-873. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67776232E1A7]
 
Peroxisome proliferator-activated receptor beta/delta exerts a strong protection from ischemic acute renal failure.
Letavernier E., Perez J., Joye E., Bellocq A., Fouqueray B., Haymann J.P., Heudes D., Wahli W., Desvergne B., Baud L., 2005. Journal of the American Society of Nephrology, 16 (8) pp. 2395-2402. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_46205B0D685E]
 
PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs.
Feige J.N., Sage D., Wahli W., Desvergne B., Gelman L., 2005. Microscopy Research and Technique, 68 (1) pp. 51-58. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DB90881204B8]
 
PPARs in diseases: control mechanisms of inflammation.
Kostadinova R., Wahli W., Michalik L., 2005. Current Medicinal Chemistry, 12 (25) pp. 2995-3009. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E19ECA41F0F]
 
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
Genolet R., Kersten S., Braissant O., Mandard S., Tan N.S., Bucher P., Desvergne B., Michalik L., Wahli W., 2005. Journal of Biological Chemistry, 280 (25) pp. 24143-24152. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_038A574254CF]
 
Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors.
Marty N., Dallaporta M., Foretz M., Emery M., Tarussio D., Bady I., Binnert C., Beermann F., Thorens B., 2005. Journal of Clinical Investigation, 115 (12) pp. 3545-3553. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_899311492768]
 
Retinoic acid signaling affects cortical synchrony during sleep.
Maret S., Franken P., Dauvilliers Y., Ghyselinck N.B., Chambon P., Tafti M., 2005. Science, 310 (5745) pp. 111-113.
[DOI][WoS][Pmid][serval:BIB_46F4E5D8BDCC]
 
Scaffold attachment factor B1 directly interacts with nuclear receptors in living cells and represses transcriptional activity.
Debril M.B., Dubuquoy L., Feige J.N., Wahli W., Desvergne B., Auwerx J., Gelman L., 2005. Journal of Molecular Endocrinology, 35 (3) pp. 503-517. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A9BFC6B17C5E]
 
Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.
Michalik L., Feige J.N., Gelman L., Pedrazzini T., Keller H., Desvergne B., Wahli W., 2005. Molecular Endocrinology, 19 (9) pp. 2335-2348. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8EEF173FBE2E]
 
Structure-function analysis of the human TFIIB-related factor II protein reveals an essential role for the C-terminal domain in RNA polymerase III transcription.
Saxena A., Ma B., Schramm L., Hernandez N., 2005. Molecular and Cellular Biology, 25 (21) pp. 9406-9418. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D8249FA738F2]
 
The average inter-crossing number of equilateral random walks and polygons
Diao Y., Dobay A., Stasiak A., 2005. Journal of Physics A: Mathematical and General, 38 (35) pp. 7601-7616.
[DOI][WoS][serval:BIB_31F454720298]
 
The effect of the light and gravity on hypocotyl growth orientation.
Lariguet P., Fankhauser C., 2005. pp. 277-284 dans Wada M., Shimazaki K., Iino M. (eds.) Light Sensing in Plants, Springer.
[DOI][serval:BIB_35118]
 
The G0/G1 switch gene 2 is a novel PPAR target gene.
Zandbergen F., Mandard S., Escher P., Tan N.S., Patsouris D., Jatkoe T., Rojas-Caro S., Madore S., Wahli W., Tafuri S. et al., 2005. Biochemical Journal, 392 (Pt 2) pp. 313-324. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C6EBFB10FA90]
 
Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.
Di-Poï N., Desvergne B., Michalik L., Wahli W., 2005. Journal of Biological Chemistry, 280 (46) pp. 38700-38710. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DCEEC5B9FD8A]
2004
 
Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action.
Rieusset J., Seydoux J., Anghel S.I., Escher P., Michalik L., Soon Tan N., Metzger D., Chambon P., Wahli W., Desvergne B., 2004. Molecular Endocrinology, 18 (10) pp. 2363-2377. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5C588D6B88D1]
 
Be fit or be sick: peroxisome proliferator-activated receptors are down the road.
Desvergne B., Michalik L., Wahli W., 2004. Molecular Endocrinology, 18 (6) pp. 1321-1332. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3B722A333ADA]
 
Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.
Burki F., Kaessmann H., 2004. Nature Genetics, 36 (10) pp. 1061-1063.
[DOI][WoS][Pmid][serval:BIB_51AB4869F8C0]
 
Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment.
Dermitzakis E.T., Kirkness E., Schwarz S., Birney E., Reymond A., Antonarakis S.E., 2004. Genome Research, 14 (5) pp. 852-859. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7C2FEB973B83]
 
Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing.
Tan N.S., Michalik L., Di-Poï N., Desvergne B., Wahli W., 2004. Biochemical Society Transactions, 32 (Pt 1) pp. 97-102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B7D39DF5C459]
 
Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.
Tan N.S., Michalik L., Di-Poï N., Ng C.Y., Mermod N., Roberts A.B., Desvergne B., Wahli W., 2004. EMBO Journal, 23 (21) pp. 4211-4221. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C76B9D75FB34]
 
Extensive gene traffic on the mammalian X chromosome.
Emerson J.J., Kaessmann H., Betrán E., Long M., 2004. Science, 303 (5657) pp. 537-540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7EF7D0855D09]
Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis.
Di-Poï N., Michalik L., Desvergne B., Wahli W., 2004. Lipids, 39 (11) pp. 1093-1099. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7746765F1642]
 
Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone.
Jové M., Salla J., Planavila A., Cabrero A., Michalik L., Wahli W., Laguna J.C., Vázquez-Carrera M., 2004. Journal of Lipid Research, 45 (1) pp. 113-123. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_48B12042AEDF]
 
In vivo activation of PPAR target genes by RXR homodimers.
Ijpenberg A., Tan N.S., Gelman L., Kersten S., Seydoux J., Xu J., Metzger D., Canaple L., Chambon P., Wahli W. et al., 2004. EMBO Journal, 23 (10) pp. 2083-2091. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A65D03A89DE0]
 
Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha.
Sanguino E., Ramón M., Michalik L., Wahli W., Alegret M., Sánchez R.M., Vázquez-Carrera M., Laguna J.C., 2004. Biochemical Pharmacology, 67 (1) pp. 157-166. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AAA10B68BD71]
 
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse.
Imai T., Takakuwa R., Marchand S., Dentz E., Bornert J.M., Messaddeq N., Wendling O., Mark M., Desvergne B., Wahli W. et al., 2004. Proceedings of the National Academy of Sciences of the United States of America, 101 (13) pp. 4543-4547. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D69D7518C323]
 
Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.
Tan N.S., Michalik L., Desvergne B., Wahli W., 2004. Expert Opinion on Therapeutic Targets, 8 (1) pp. 39-48. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_36565944F9B0]
 
Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation.
Mao-Qiang M., Fowler A.J., Schmuth M., Lau P., Chang S., Brown B.E., Moser A.H., Michalik L., Desvergne B., Wahli W. et al., 2004. Journal of Investigative Dermatology, 123 (2) pp. 305-312. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6BF7AB69B983]
 
Peroxisome-proliferator-activated receptors and cancers: complex stories.
Michalik L., Desvergne B., Wahli W., 2004. Nature Reviews. Cancer, 4 (1) pp. 61-70. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_76D9CE5EF974]
 
Phytochrome-mediated light signalling in Arabidopsis.
Schepens I., Duek P., Fankhauser C., 2004. Current Opinion in Plant Biology, 7 (5) pp. 564-569. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_801D9821BD83]
 
PPARalpha governs glycerol metabolism.
Patsouris D., Mandard S., Voshol P.J., Escher P., Tan N.S., Havekes L.M., Koenig W., März W., Tafuri S., Wahli W. et al., 2004. Journal of Clinical Investigation, 114 (1) pp. 94-103. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A4E93A04C9B4]
 
PPARs as drug targets to modulate inflammatory responses?
Genolet R., Wahli W., Michalik L., 2004. Current Drug Targets. Inflammation and Allergy, 3 (4) pp. 361-375. Peer-reviewed.
[Pmid][serval:BIB_31EA877D4824]
 
PPARs in health and disease : central roles in energy homeostasis and tissue repair.
Wahli W, Michalik L, Desvergne B, 2004. BIO, 11 pp. 26-31. Peer-reviewed.
[serval:BIB_32861]
 
Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta.
Wang D., Wang H., Shi Q., Katkuri S., Walhi W., Desvergne B., Das S.K., Dey S.K., DuBois R.N., 2004. Cancer Cell, 6 (3) pp. 285-295. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E4C9D3899591]
 
Regional variations in ABC transporter expression along the mouse intestinal tract.
Mutch D.M., Anderle P., Fiaux M., Mansourian R., Vidal K., Wahli W., Williamson G., Roberts M.A., 2004. Physiological Genomics, 17 (1) pp. 11-20. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7CBC6E5E85AA]
 
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution.
International Chicken Genome Sequencing Consortium, including Duplanloup I., Kaessmann H., Reymond A., 2004. Nature, 432 (7018) pp. 695-716.
[DOI][WoS][Pmid][serval:BIB_BE48F0F02A81]
 
Sex chromosomes and male functions: where do new genes go?
Betrán E., Emerson J.J., Kaessmann H., Long M., 2004. Cell Cycle, 3 (7) pp. 871-873.
[WoS][Pmid][serval:BIB_6C594C4BA7C0]
 
The degradation of HFR1, a putative bHLH class transcription factor involved in light signaling, is regulated by phosphorylation and requires COP1.
Duek P.D., Elmer M.V., van Oosten V.R., Fankhauser C., 2004. Current Biology, 14 (24) pp. 2296-2301. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1F398A440B22]
 
The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.
Mandard S., Zandbergen F., Tan N.S., Escher P., Patsouris D., Koenig W., Kleemann R., Bakker A., Veenman F., Wahli W. et al., 2004. Journal of Biological Chemistry, 279 (33) pp. 34411-34420. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DE95C5E5D38E]
 
The ENCODE (ENCyclopedia Of DNA Elements) Project.
ENCODE Project Consortium, Reymond Alexandre, 2004. Science, 306 (5696) pp. 636-640.
[DOI][WoS][Pmid][serval:BIB_33406]
The European dimension for the mouse genome mutagenesis program.
Auwerx J., Avner P., Baldock R., Ballabio A., Balling R., Barbacid M., Berns A., Bradley A., Brown S., Carmeliet P. et al., 2004. Nature genetics, 36 (9) pp. 925-927. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6D7C871DF5CA]
 
Understanding the coordinated effects of PPARs on lipid metabolism using microarrays.
Kersten S., Escher P., Tafuri S., Wahli W., 2004. pp. 249-263 dans Berger A., Roberts M.A. (eds.) Unraveling Lipid Metabolism with Microarrays chap. 11, CRC Press.
[serval:BIB_32863]
2003
 
Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member.
Michalik L., Desvergne B., Wahli W., 2003/04. Current opinion in lipidology, 14 (2) pp. 129-135. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2683817E543A]
 
A conserved oligomerization domain in drosophila Bazooka/PAR-3 is important for apical localization and epithelial polarity.
Benton R., St Johnston D., 2003. Current Biology, 13 (15) pp. 1330-1334.
[DOI][WoS][Pmid][serval:BIB_DBBE3A288F9D]
 
Drosophila PAR-1 and 14-3-3 inhibit Bazooka/PAR-3 to establish complementary cortical domains in polarized cells.
Benton R., St Johnston D., 2003. Cell, 115 (6) pp. 691-704.
[DOI][WoS][Pmid][serval:BIB_9863F40E17C9]
 
Human and chimpanzee nucleotide diversity.
Kaessmann H., 2003. dans Cooper D. N. (eds.) Encyclopedia of the human genome., Nature Publishing Group.
[serval:BIB_36FF379EA2CF]
 
Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?
Tan N.S., Michalik L., Desvergne B., Wahli W., 2003. American Journal of Clinical Dermatology, 4 (8) pp. 523-530.
[DOI][WoS][Pmid][serval:BIB_8E89E274F7A5]
 
PPARs: nuclear receptors involved in the control of inflammation
Michalik L., Tan N. S., Wahli W., Desvergne B., 2003. pp. 419-435 dans Duttaroy A.K., Spener F. (eds.) Cellular proteins and their fatty acids in health and disease chap. 24, Wiley VCH.
[serval:BIB_715416E9869F]
 
The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.
Di-Poï N., Michalik L., Tan N.S., Desvergne B., Wahli W., 2003. Journal of Steroid Biochemistry and Molecular Biology, 85 (2-5) pp. 257-265.
[DOI][WoS][Pmid][serval:BIB_BA2FFA6367EA]
 
The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium.
Doerflinger H., Benton R., Shulman J.M., St Johnston D., 2003. Development, 130 (17) pp. 3965-3975. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A6B188E22449]
2002
 
Cell polarity: posterior Par-1 prevents proteolysis.
Benton R., St Johnston D., 2002/07. Current Biology, 12 (14) pp. R479-R481.
[DOI][WoS][Pmid][serval:BIB_392233F0AE95]
 
Large Family With Maturity-Onset Diabetes of the Young and a Novel V121I Mutation in HNF4A
Monney C.T., Kaltenrieder V., Cousin P., Bonny C, Schorderet D.F., 2002/05. Human Mutation, 20 (3) p. 230.
[Pmid][serval:BIB_416EFB13A593]
 
Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation.
Benton R., Palacios I.M., St Johnston D., 2002. Developmental Cell, 3 (5) pp. 659-671.
[DOI][WoS][Pmid][serval:BIB_FD75FA9658E8]
2001
 
A novel highly informative polyA microsatellite on the telomeric side of the INK4a/ARF locus
Chaubert P., Burri N., Cousin P., Shaw P., 2001. Molecular and Cellular Probes, 15 (3) pp. 183-185.
[DOI][WoS][Pmid][serval:BIB_BDB1D4B729F8]
 
PAR-1 is required for the maintenance of oocyte fate in Drosophila.
Huynh J.R., Shulman J.M., Benton R., St Johnston D., 2001. Development, 128 (7) pp. 1201-1209.
[WoS][Pmid][serval:BIB_6612569EABF0]
2000
 
The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole.
Shulman J.M., Benton R., St Johnston D., 2000/05. Cell, 101 (4) pp. 377-388.
[DOI][WoS][Pmid][serval:BIB_E1B04AC40760]
 
Physical map of 17p13 and the genes adjacent to p53
Cousin P., Billotte J., Chaubert P., Shaw P., 2000. Genomics, 63 (1) pp. 60-68.
[DOI][WoS][Pmid][serval:BIB_B47DB5A03734]
1997
Enclosed Desires: a Study of the Wooing Group
Renevey D., 1997. pp. 39-62 dans Pollard W. F. , Boenig R. (eds.) Mysticism and Spirituality in Medieval England, D.S. Brewer.
[URN][serval:BIB_F0B5841F9CF9]
1994
 
Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells.
Thorens B., Roduit R., 1994/08. Biochemical Society Transactions, 22 (3) pp. 684-687.
[WoS][Pmid][serval:BIB_19429CB88950]
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