Ludwig Lausanne Branch

Publications | Phd and Masters theses

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863 publications

... | 2021 | 2020 | 2019 | ...
2021
CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.
Forlani G., Michaux J., Pak H., Huber F., Marie Joseph E.L., Ramia E., Stevenson B.J., Linnebacher M., Accolla R.S., Bassani-Sternberg M., 2021. Molecular & cellular proteomics, 20 p. 100032. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_848F6AADEDBE]
 
Computer-Aided Drug Design for Cancer Therapy
Daina Antoine, Röhrig Ute F., Zoete Vincent, 2021. pp. 386-401 dans Systems Medicine, Elsevier.
[DOI][serval:BIB_7CB4A862858D]
Editorial: Memory T Cells in Chronic Infections and Tumors.
Hofmann M., Jandus C., Lee L.N., Utzschneider D.T., 2021. Frontiers in immunology, 12 p. 656010. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DED547C3EF90]
 
Efficacy of cancer vaccines in selected gynaecological breast and ovarian cancers: A 20-year systematic review and meta-analysis.
Dafni U., Martín-Lluesma S., Balint K., Tsourti Z., Vervita K., Chenal J., Coukos G., Zaman K., Sarivalasis A., Kandalaft L.E., 2021/01. European journal of cancer, 142 pp. 63-82. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D084831A838B]
Extensive tissue-specific expression variation and novel regulators underlying circadian behavior.
Litovchenko M., Meireles-Filho ACA, Frochaux M.V., Bevers RPJ, Prunotto A., Anduaga A.M., Hollis B., Gardeux V., Braman V.S., Russeil JMC et al., 2021/01. Science advances, 7 (5) pp. eabc3781. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DD598AB6CFE4]
Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society.
Lucas S., Tencerova M., von der Weid B., Andersen T.L., Attané C., Behler-Janbeck F., Cawthorn W.P., Ivaska K.K., Naveiras O., Podgorski I. et al., 2021. Frontiers in endocrinology, 12 p. 744527. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C15C8E462E06]
 
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.
Klionsky D.J., Abdel-Aziz A.K., Abdelfatah S., Abdellatif M., Abdoli A., Abel S., Abeliovich H., Abildgaard M.H., Abudu Y.P., Acevedo-Arozena A. et al., 2021/01. Autophagy, 17 (1) pp. 1-382. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_345DDF9FE897]
Immune Checkpoint and Telomerase Crosstalk Is Mediated by miRNA-138 in Bladder Cancer.
El Ahanidi H., El Azzouzi M., Hafidi Alaoui C., Tetou M., Bensaid M., Chaoui I., Benbacer L., Hassan I., Oukabli M., Michaud K. et al., 2021. Frontiers in oncology, 11 p. 795242. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3DD67FC130B6]
In Vivo Evaluation of Gallium-68-Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors.
Stroet MCM, de Blois E., Haeck J., Seimbille Y., Mezzanotte L., de Jong M., Löwik CWGM, Panth K.M., 2021. Contrast media & molecular imaging, 2021 p. 2853522. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_475468701436]
Sensitive Immunopeptidomics by Leveraging Available Large-Scale Multi-HLA Spectral Libraries, Data-Independent Acquisition, and MS/MS Prediction.
Pak H., Michaux J., Huber F., Chong C., Stevenson B.J., Müller M., Coukos G., Bassani-Sternberg M., 2021. Molecular & cellular proteomics, 20 p. 100080. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DCFCF966CE50]
SMARCA4-Deficient Carcinoma of Uterine Cervix Resembling SCCOHT-Case Report.
Sirák I., Laco J., Vošmiková H., Mell L.K., Herrera F.G., Šenkeříková M., Vošmik M., 2021. Pathology oncology research, 27 p. 1610003. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A02C55D57CF2]
Temozolomide: An Updated Overview of Resistance Mechanisms, Nanotechnology Advances and Clinical Applications.
Ortiz R., Perazzoli G., Cabeza L., Jiménez-Luna C., Luque R., Prados J., Melguizo C., 2021. Current neuropharmacology, 19 (4) pp. 513-537. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5731184354D4]
The Promise of Personalized TCR-Based Cellular Immunotherapy for Cancer Patients.
Arnaud M., Bobisse S., Chiffelle J., Harari A., 2021. Frontiers in immunology, 12 p. 701636. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_132C3057D946]
Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients.
Bibert S., Guex N., Lourenco J., Brahier T., Papadimitriou-Olivgeris M., Damonti L., Manuel O., Liechti R., Götz L., Tschopp J. et al., 2021. Frontiers in immunology, 12 p. 666163. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_91CEC9119F7E]
UCell: Robust and scalable single-cell gene signature scoring.
Andreatta M., Carmona S.J., 2021. Computational and structural biotechnology journal, 19 pp. 3796-3798. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ADC3FAC598DC]
Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery.
Baumgaertner P., Sankar M., Herrera F.G, Benedetti F., Barras D., Thierry A.C., Dangaj D., Kandalaft L.E., Coukos G., Xenarios I. et al., 2021. Frontiers in immunology, 12 p. 633910. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E707FFE34C52]
2020
 
Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer.
Ferrara R., Imbimbo M., Malouf R., Paget-Bailly S., Calais F., Marchal C., Westeel V., 2020/12/14. The Cochrane database of systematic reviews, 12 (12) pp. CD013257. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6A29A6569DE6]
 
Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment.
Gannon P.O., Harari A., Auger A., Murgues C., Zangiacomi V., Rubin O., Ellefsen Lavoie K., Guillemot L., Navarro Rodrigo B., Nguyen-Ngoc T. et al., 2020/12. Cytotherapy, 22 (12) pp. 780-791. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_30851676B0A7]
 
Disturbed mitochondrial dynamics in CD8<sup>+</sup> TILs reinforce T cell exhaustion.
Yu Y.R., Imrichova H., Wang H., Chao T., Xiao Z., Gao M., Rincon-Restrepo M., Franco F., Genolet R., Cheng W.C. et al., 2020/12. Nature immunology, 21 (12) pp. 1540-1551. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_89908ED24FA7]
Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging.
Zambito G., Gaspar N., Ridwan Y., Hall M.P., Shi C., Kirkland T.A., Encell L.P., Löwik C., Mezzanotte L., 2020/12. Molecular imaging and biology, 22 (6) pp. 1523-1531. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1FD4332877FF]
Genomic and transcriptomic landscape of conjunctival melanoma.
Cisarova K., Folcher M., El Zaoui I., Pescini-Gobert R., Peter V.G., Royer-Bertrand B., Zografos L., Schalenbourg A., Nicolas M., Rimoldi D. et al., 2020/12. PLoS genetics, 16 (12) pp. e1009201. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4F66F37907D8]
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes
Chong Chloe, Müller Markus, Pak HuiSong, Harnett Dermot, Huber Florian, Grun Delphine, Leleu Marion, Auger Aymeric, Arnaud Marion, Stevenson Brian J. et al., 2020/12. Nature Communications, 11 (1). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_03EA897A1141]
Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes.
Pesce S., Trabanelli S., Di Vito C., Greppi M., Obino V., Guolo F., Minetto P., Bozzo M., Calvi M., Zaghi E. et al., 2020/11/25. Cancers, 12 (12) pp. E3504. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_96E040FC6BB3]
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.
Pais Ferreira D., Silva J.G., Wyss T., Fuertes Marraco S.A., Scarpellino L., Charmoy M., Maas R., Siddiqui I., Tang L., Joyce J.A. et al., 2020/11/17. Immunity, 53 (5) pp. 985-1000.e11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A0FD9237651F]
Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Shang M., Cappellesso F., Amorim R., Serneels J., Virga F., Eelen G., Carobbio S., Rincon M.Y., Maechler P., De Bock K. et al., 2020/11. Nature, 587 (7835) pp. 626-631. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3434B6E6C298]
Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment.
Zoetemelk M., Ramzy G.M., Rausch M., Koessler T., van Beijnum J.R., Weiss A., Mieville V., Piersma S.R., de Haas R.R., Delucinge-Vivier C. et al., 2020/11. Molecular oncology, 14 (11) pp. 2894-2919. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6B1C1DF10DF7]
 
Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Devlin J.R., Alonso J.A., Ayres C.M., Keller GLJ, Bobisse S., Vander Kooi C.W., Coukos G., Gfeller D., Harari A., Baker B.M., 2020/11. Nature chemical biology, 16 (11) pp. 1269-1276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_186F0AD1C570]
Transgenic CD8αβ co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells.
Bajwa G., Lanz I., Cardenas M., Brenner M.K., Arber C., 2020/11. Journal for immunotherapy of cancer, 8 (2) pp. e001487. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FD8350547BA6]
 
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Wells D.K., van Buuren M.M., Dang K.K., Hubbard-Lucey V.M., Sheehan KCF, Campbell K.M., Lamb A., Ward J.P., Sidney J., Blazquez A.B. et al., 2020/10/29. Cell, 183 (3) pp. 818-834.e13. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F6095670EC38]
Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology.
Krebs F.S., Gérard C., Wicky A., Aedo-Lopez V., Missiaglia E., Bisig B., Trimech M., Michielin O., Homicsko K., Zoete V., 2020/10/28. International journal of molecular sciences, 21 (21) pp. E8021. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_44F221AEB60A]
 
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.
Valiente M., Van Swearingen AED, Anders C.K., Bairoch A., Boire A., Bos P.D., Cittelly D.M., Erez N., Ferraro G.B., Fukumura D. et al., 2020/10/15. Cancer Research, 80 (20) pp. 4314-4323. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_47CE3A073F78]
 
All systems go: converging synthetic biology and combinatorial treatment for CAR-T cell therapy.
Lanitis E., Coukos G., Irving M., 2020/10. Current opinion in biotechnology, 65 pp. 75-87. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_97CF39EFF89C]
 
Are dendritic cells the most appropriate therapeutic vaccine for patients with ovarian cancer?
Martin-Lluesma S., Graciotti M., Grimm A.J., Boudousquié C., Chiang C.L., Kandalaft L.E., 2020/10. Current opinion in biotechnology, 65 pp. 190-196. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4448266B5C3F]
 
Biotechnologies to tackle the challenge of neoantigen identification.
Arnaud M., Duchamp M., Bobisse S., Renaud P., Coukos G., Harari A., 2020/10. Current opinion in biotechnology, 65 pp. 52-59. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_78FA51F85D77]
 
Challenges and advantages of cell therapy manufacturing under Good Manufacturing Practices within the hospital setting.
Iancu E.M., Kandalaft L.E., 2020/10. Current opinion in biotechnology, 65 pp. 233-241. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B35118F36861]
 
Cryoablation and immunotherapy of cancer.
Yakkala C., Denys A., Kandalaft L., Duran R., 2020/10. Current opinion in biotechnology, 65 pp. 60-64. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FF3698E414D7]
 
Editorial overview: Pharmaceutical biotechnology: new frontiers in cancer immunotherapy.
Kandalaft L.E., Graciotti M., 2020/10. Current opinion in biotechnology, 65 pp. iii-v. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F4B29364362]
 
Electroporation as a method of choice to generate genetically modified dendritic cell cancer vaccines.
Ahmed R., Sayegh N., Graciotti M., Kandalaft L.E., 2020/10. Current opinion in biotechnology, 65 pp. 142-155. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3754407C879B]
High versus low dose irradiation for tumor immune reprogramming.
de Olza M.O., Bourhis J., Irving M., Coukos G., Herrera F.G., 2020/10. Current opinion in biotechnology, 65 pp. 268-283. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_330632946BBD]
In Vivo Evaluation of Indium-111-Labeled 800CW as a Necrosis-Avid Contrast Agent.
Stroet MCM, de Blois E., Stuurman D.C., de Ridder CMA, Haeck J., Seimbille Y., Mezzanotte L., de Jong M., Löwik CWGM, Panth K.M., 2020/10. Molecular imaging and biology, 22 (5) pp. 1333-1341. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CF4B3594ECD7]
 
Metabolic and epigenetic regulation of T-cell exhaustion.
Franco F., Jaccard A., Romero P., Yu Y.R., Ho P.C., 2020/10. Nature metabolism, 2 (10) pp. 1001-1012. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C6CC159592FD]
T-cell repertoire analysis and metrics of diversity and clonality.
Chiffelle J., Genolet R., Perez M.A., Coukos G., Zoete V., Harari A., 2020/10. Current opinion in biotechnology, 65 pp. 284-295. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_598F3EDCA20B]
 
Survival of the fetus: cervical cancer and pregnancy, a challenging combination.
Levy L., Meuwly J.Y., Sarivalasis A., Achtari C., Mathevet P., Herrera F.G., 2020/09/05. Lancet, 396 (10252) p. 725. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_16AC5A00A805]
Mineral and Amino Acid Profiling of Different Hematopoietic Populations from the Mouse Bone Marrow.
Girotra M., Monnard C., Konz T., Sizzano F., Goulet L., Godin J.P., Coukos G., Rezzi S., Vannini N., 2020/09/03. International journal of molecular sciences, 21 (17) p. 6444. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_477EEDC014A0]
pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology.
Pethő Z., Najder K., Carvalho T., McMorrow R., Todesca L.M., Rugi M., Bulk E., Chan A., Löwik CWGM, Reshkin S.J. et al., 2020/09/02. Cancers, 12 (9) pp. E2484. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_72DDC078615F]
 
Antitumour dendritic cell vaccination in a priming and boosting approach.
Harari A., Graciotti M., Bassani-Sternberg M., Kandalaft L.E., 2020/09. Nature reviews. Drug discovery, 19 (9) pp. 635-652. Peer-reviewed.
[DOI][Pmid][serval:BIB_14F09B31BAF0]
 
High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays.
Brandenberg N., Hoehnel S., Kuttler F., Homicsko K., Ceroni C., Ringel T., Gjorevski N., Schwank G., Coukos G., Turcatti G. et al., 2020/09. Nature biomedical engineering, 4 (9) pp. 863-874. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_71E34713FAA0]
Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222 by combinatorial peptide library screening.
Bovay A., Zoete V., Rizkallah P.J., Beck K., Delbreil P., Speiser D.E., Cole D.K., Fuertes Marraco S.A., 2020/09. Molecular immunology, 125 pp. 43-50. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_46FDF2862443]
 
The hidden side of PD-L1.
Jaccard A., Ho P.C., 2020/09. Nature cell biology, 22 (9) pp. 1031-1032. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CDDD22AA09ED]
 
Turning up the heat on non-immunoreactive tumours: opportunities for clinical development.
Ochoa de Olza M., Navarro Rodrigo B., Zimmermann S., Coukos G., 2020/09. The Lancet. Oncology, 21 (9) pp. e419-e430. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_208B57498352]
 
177Lu radiolabeling and preclinical theranostic study of 1C1m-Fc: an anti-TEM-1 scFv-Fc fusion protein in soft tissue sarcoma
Delage J.A., Faivre-Chauvet A., Fierle J.K., Gnesin S., Schaefer N., Coukos G., Dunn S.M., Viertl D., Prior J.O., 2020/08/17. EJNMMI research, 10 (1) p. 98. Peer-reviewed.
[DOI][Pmid][serval:BIB_4E04534CDA56]
NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform.
Gaspar N., Zambito G., Dautzenberg IJC, Cramer S.J., Hoeben R.C., Lowik C., Walker J.R., Kirkland T.A., Smith T.P., van Weerden W.M. et al., 2020/08/15. International journal of molecular sciences, 21 (16). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F4F6102BC551]
Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment.
Dumas A.A., Pomella N., Rosser G., Guglielmi L., Vinel C., Millner T.O., Rees J., Aley N., Sheer D., Wei J. et al., 2020/08/03. The EMBO journal, 39 (15) pp. e103790. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FFF9B15DBC96]
 
Correction to: Preclinical Evaluation and Dosimetry of [111In] CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1)
Cicone Francesco, Denoël Thibaut, Gnesin Silvano, Riggi Nicolo, Irving Melita, Jakka Gopinadh, Schaefer Niklaus, Viertl David, Coukos George, Prior John O., 2020/08. 1.
[DOI][WoS][Pmid][serval:BIB_81A7D3CC3803]
 
Distinct and shared gene expression for human innate versus adaptive helper lymphoid cells.
Ercolano G., Wyss T., Salomé B., Romero P., Trabanelli S., Jandus C., 2020/08. Journal of leukocyte biology, 108 (2) pp. 723-737. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4DA23DC9CF93]
Guillain-Barré syndrome after adoptive cell therapy with tumor-infiltrating lymphocytes.
Orcurto A., Hottinger A., Wolf B., Navarro Rodrigo B., Ochoa de Olza M., Auger A., Kuntzer T., Comte D., Zimmer V., Gannon P. et al., 2020/08. Journal for immunotherapy of cancer, 8 (2) pp. e001155. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C930B13A53AD]
Preclinical Evaluation and Dosimetry of [111In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1).
Cicone F., Denoël T., Gnesin S., Riggi N., Irving M., Jakka G., Schaefer N., Viertl D., Coukos G., Prior J.O., 2020/08. Molecular imaging and biology, 22 (4) pp. 979-991. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_813B48F40C5F]
 
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes.
Adams S.F., Grimm A.J., Chiang C.L., Mookerjee A., Flies D., Jean S., McCann G.A., Michaux J., Pak H., Huber F. et al., 2020/08. Journal for immunotherapy of cancer, 8 (2) pp. e000875. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7B7CF92C7BCB]
Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors.
Dosset M., Joseph E.L., Rivera Vargas T., Apetoh L., 2020/07/19. Cells, 9 (7). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED310CC0AADA]
 
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.
Akkari L., Bowman R.L., Tessier J., Klemm F., Handgraaf S.M., de Groot M., Quail D.F., Tillard L., Gadiot J., Huse J.T. et al., 2020/07/15. Science translational medicine, 12 (552) pp. eaaw7843. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1B0920FD434E]
A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts.
Krasny L., Bland P., Burns J., Lima N.C., Harrison P.T., Pacini L., Elms M.L., Ning J., Martinez V.G., Yu Y.R. et al., 2020/07/14. Disease models & mechanisms, 13 (7) pp. dmm044586. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AECF31D38959]
 
Pharmacological disruption of the Notch transcription factor complex.
Lehal R., Zaric J., Vigolo M., Urech C., Frismantas V., Zangger N., Cao L., Berger A., Chicote I., Loubéry S. et al., 2020/07/14. Proceedings of the National Academy of Sciences of the United States of America, 117 (28) pp. 16292-16301. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_53A51DDF8D0E]
 
Biological functions of lymphatic vessels.
Petrova T.V., Koh G.Y., 2020/07/10. Science, 369 (6500). Peer-reviewed.
[DOI][Pmid][serval:BIB_0975AC40A1DE]
 
Multielemental Analysis of Low-Volume Samples Reveals Cancer-Specific Profile in Serum and Sorted Immune Cells
Konz Tobias, Monnard Caroline, Restrepo Marcela Rincon, Laval Julie, Sizzano Federico, Girotra Mukul, Dammone Gabriele, Palini Alessio, Coukos George, Rezzi Serge et al., 2020/07/07. Analytical Chemistry, 92 (13) pp. 8750-8758.
[DOI][Pmid][serval:BIB_3A58DA889942]
Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4<sup>+</sup> T cells.
Rath J.A., Bajwa G., Carreres B., Hoyer E., Gruber I., Martínez-Paniagua M.A., Yu Y.R., Nouraee N., Sadeghi F., Wu M. et al., 2020/07. Science advances, 6 (27) pp. eaaz7809. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D26F38B87AE4]
 
Nanoparticles in Colorectal Cancer Therapy: Latest In Vivo Assays, Clinical Trials, and Patents.
Cabeza L., Perazzoli G., Mesas C., Jiménez-Luna C., Prados J., Rama A.R., Melguizo C., 2020/06/26. AAPS PharmSciTech, 21 (5) p. 178. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1654D1E8D688]
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells
Klemm F., Maas R.R., Bowman R.L., Kornete M., Soukup K., Nassiri S., Brouland J.P., Iacobuzio-Donahue C.A., Brennan C., Tabar V. et al., 2020/06/25. Cell, 181 (7) pp. 1643-1660.e17. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B25384BE18E8]
Projecting single-cell transcriptomics data onto a reference T cell atlas to interpret immune responses
Andreatta Massimo, Corria-Osorio Jesus, Müller Sören, Cubas Rafael, Coukos George, Carmona Santiago J., 2020/06/24..
[URN][DOI][serval:BIB_2A40AFE9A2C6]
 
Quantitative and qualitative impairments in dendritic cell subsets of patients with ovarian or prostate cancer.
Mastelic-Gavillet B., Sarivalasis A., Lozano L.E., Wyss T., Inoges S., de Vries IJM, Dartiguenave F., Jichlinski P., Derrè L., Coukos G. et al., 2020/06/23. European journal of cancer, 135 pp. 173-182. Peer-reviewed.
[DOI][Pmid][serval:BIB_2DED61B64BB4]
Innate Immune Cells and Their Contribution to T-Cell-Based Immunotherapy.
Ginefra P., Lorusso G., Vannini N., 2020/06/22. International journal of molecular sciences, 21 (12) p. 4441. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0AC8DC8B4A8A]
Engineering Strategies to Enhance TCR-Based Adoptive T Cell Therapy.
Rath J.A., Arber C., 2020/06/18. Cells, 9 (6) p. 1485. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_53031F025A7F]
Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation.
Norden P.R., Sabine A., Wang Y., Demir C.S., Liu T., Petrova T.V., Kume T., 2020/06/08. eLife, 9 pp. e53814. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_066C420F0AD8]
Deciphering the Mechanisms of Improved Immunogenicity of Hypochlorous Acid-Treated Antigens in Anti-Cancer Dendritic Cell-Based Vaccines.
Graciotti M., Marino F., Pak H., Baumgaertner P., Thierry A.C., Chiffelle J., Perez MAS, Zoete V., Harari A., Bassani-Sternberg M. et al., 2020/06/02. Vaccines, 8 (2). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_0A84027C58CB]
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Moschouri E., Vionnet J., Giostra E., Daccord C., Lazor R., Sciarra A., Letovanec I., Sempoux C., Gonzalez M., Unger S. et al., 2020/06. Liver transplantation, 26 (6) pp. 840-844. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_67847DD9BC0A]
Resolution of Corneal Fibrosis After Descemet's Stripping Automated Endothelial Keratoplasty: A Case Report.
Zola M., Kim J., Petrelli M., Schmutz L., Hashemi K., Kymionis G., 2020/06. Ophthalmology and therapy, 9 (2) pp. 349-354. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_19CAFA3B6063]
Mélanome localement avancé et métastatique : nouveautés [Locally advanced and metastatic melanoma : novelties]
Huber A., Latifyan S., Nikolopoulou A., Homicsko K., Berthod G., Michielin O., Özdemir B.C., 2020/05/27. Revue medicale suisse, 16 (695) pp. 1092-1097. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_E5DDB348D97F]
Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer treatment.
Gomez-Cadena A., Barreto A., Fioretino S., Jandus C., 2020/05/18. Cell stress, 4 (7) pp. 154-166. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1DAAFE3927F7]
 
Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma.
Dheilly E., Battistello E., Katanayeva N., Sungalee S., Michaux J., Duns G., Wehrle S., Sordet-Dessimoz J., Mina M., Racle J. et al., 2020/05/11. Cancer cell, 37 (5) pp. 674-689.e12. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C0FB07A8B571]
 
Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature.
Ansar M., Ebstein F., Özkoç H., Paracha S.A., Iwaszkiewicz J., Gesemann M., Zoete V., Ranza E., Santoni F.A., Sarwar M.T. et al., 2020/05/08. Human molecular genetics, 29 (7) pp. 1132-1143. Peer-reviewed.
[DOI][Pmid][serval:BIB_7528AD86E93D]
[99mTc]Tc-PSMA-I&S-SPECT/CT: experience in prostate cancer imaging in an outpatient center.
Werner P., Neumann C., Eiber M., Wester H.J., Schottelius M., 2020/05/07. EJNMMI research, 10 (1) p. 45. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5A12CBAF1DF6]
"Luke! Luke! Don't! It's a trap!"-spotlight on bias in animal experiments in nuclear oncology.
Nonnekens J., Schottelius M., 2020/05. European journal of nuclear medicine and molecular imaging, 47 (5) pp. 1024-1026. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7303AE979055]
 
Immune Therapy Opportunities in Ovarian Cancer.
Kandalaft L.E., Odunsi K., Coukos G., 2020/05. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 40 pp. 1-13. Peer-reviewed.
[DOI][Pmid][serval:BIB_71D55C2B15BF]
 
Metabolic adaptation orchestrates tissue context-dependent behavior in regulatory T cells.
Wang H., Lu C.H., Ho P.C., 2020/05. Immunological reviews, 295 (1) pp. 126-139. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_06F683976602]
 
Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients.
Rockinger G.A., Guillaume P., Cachot A., Saillard M., Speiser D.E., Coukos G., Harari A., Romero P.J., Schmidt J., Jandus C., 2020/05. Journal for immunotherapy of cancer, 8 (1) pp. e000435. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EBA81BA22D33]
 
L’hématologie au temps du COVID-19 [Hematology in the time of COVID-19]
Gavillet M., Rufer N., Grandoni F., Carr Klappert J., Zermatten M.G., Cairoli A., Canellini G., Alberio L., Duchosal M.A., Spertini O. et al., 2020/04/29. Revue medicale suisse, 16 (N° 691-2) pp. 823-826. Peer-reviewed.
[Pmid][serval:BIB_C2EE66B2AA4D]
 
Roadmap for the Emerging Field of Cancer Neuroscience.
Monje M., Borniger J.C., D'Silva N.J., Deneen B., Dirks P.B., Fattahi F., Frenette P.S., Garzia L., Gutmann D.H., Hanahan D. et al., 2020/04/16. Cell, 181 (2) pp. 219-222. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_ACACD095E306]
Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus.
Lande R., Palazzo R., Gestermann N., Jandus C., Falchi M., Spadaro F., Riccieri V., James E.A., Butera A., Boirivant M. et al., 2020/04/03. Scientific reports, 10 (1) p. 5851. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_BB3E78FC1719]
 
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.
Giordano-Attianese G., Gainza P., Gray-Gaillard E., Cribioli E., Shui S., Kim S., Kwak M.J., Vollers S., Corria Osorio A.J., Reichenbach P. et al., 2020/04. Nature biotechnology, 38 (4) pp. 426-432. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EBAD72E3D84D]
 
Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials.
Chalabi M., Cardona A., Nagarkar D.R., Dhawahir Scala A., Gandara D.R., Rittmeyer A., Albert M.L., Powles T., Kok M., Herrera F.G. et al., 2020/04. Annals of oncology, 31 (4) pp. 525-531. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BC73060F5887]
 
Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma.
Ercolano G., Garcia-Garijo A., Salomé B., Gomez-Cadena A., Vanoni G., Mastelic-Gavillet B., Ianaro A., Speiser D.E., Romero P., Trabanelli S. et al., 2020/04. Cancer immunology research, 8 (4) pp. 556-564. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_61DAEC10A322]
Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density.
Gilfillan C.B., Wang C., Mohsen M.O., Rufer N., Hebeisen M., Allard M., Verdeil G., Irvine D.J., Bachmann M.F., Speiser D.E., 2020/04. European journal of immunology, 50 (4) pp. 505-514. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5686BF1354AC]
 
Neoadjuvant immune-checkpoint blockade in resectable colon cancer.
Coukos G., 2020/04. Nature medicine, 26 (4) pp. 473-474. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EEF5ED613F7B]
miR-155 Overexpression in OT-1 CD8<sup>+</sup> T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen.
Monnot G.C., Martinez-Usatorre A., Lanitis E., Lopes S.F., Cheng W.C., Ho P.C., Irving M., Coukos G., Donda A., Romero P., 2020/03/27. Molecular therapy oncolytics, 16 pp. 111-123. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_39DC24C5C585]
ER Stress Responses: An Emerging Modulator for Innate Immunity.
Di Conza G., Ho P.C., 2020/03/12. Cells, 9 (3) p. 695. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A1E25DB37FD0]
 
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Ragusa S., Prat-Luri B., González-Loyola A., Nassiri S., Squadrito M.L., Guichard A., Cavin S., Gjorevski N., Barras D., Marra G. et al., 2020/03/02. The Journal of clinical investigation, 130 (3) pp. 1199-1216. Peer-reviewed.
[DOI][Pmid][serval:BIB_C704575BD9D9]
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Wang H., Franco F., Tsui Y.C., Xie X., Trefny M.P., Zappasodi R., Mohmood S.R., Fernández-García J., Tsai C.H., Schulze I. et al., 2020/03. Nature immunology, 21 (3) pp. 298-308. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B4EB98E7D705]
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Galluzzi L., Vitale I., Warren S., Adjemian S., Agostinis P., Martinez A.B., Chan T.A., Coukos G., Demaria S., Deutsch E. et al., 2020/03. Journal for immunotherapy of cancer, 8 (1) pp. e000337. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_56620B5927E2]
 
Image-Guided Surgery: Are We Getting the Most Out of Small-Molecule Prostate-Specific-Membrane-Antigen-Targeted Tracers?
Hensbergen A.W., van Willigen D.M., van Beurden F., van Leeuwen P.J., Buckle T., Schottelius M., Maurer T., Wester H.J., van Leeuwen FWB, 2020/02/19. Bioconjugate chemistry, 31 (2) pp. 375-395. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FA17BC2E52BF]
 
HAMAP as SPARQL rules-A portable annotation pipeline for genomes and proteomes.
Bolleman J., de Castro E., Baratin D., Gehant S., Cuche B.A., Auchincloss A.H., Coudert E., Hulo C., Masson P., Pedruzzi I. et al., 2020/02/01. GigaScience, 9 (2) pp. giaa003. Peer-reviewed.
[DOI][Pmid][serval:BIB_54723D6F9FEE]
 
Mass Spectrometry Based Immunopeptidomics Leads to Robust Predictions of Phosphorylated HLA Class I Ligands.
Solleder M., Guillaume P., Racle J., Michaux J., Pak H.S., Müller M., Coukos G., Bassani-Sternberg M., Gfeller D., 2020/02. Molecular & cellular proteomics, 19 (2) pp. 390-404. Peer-reviewed.
[DOI][Pmid][serval:BIB_0EBACC6764B1]
Targeting mitochondria to stimulate hematopoiesis.
Girotra M., Naveiras O., Vannini N., 2020/01/28. Aging, 12 (2) pp. 1042-1043. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_928D9FEE87C4]
Disulfide-Linked Peptides for Blocking BTLA/HVEM Binding.
Spodzieja M., Kuncewicz K., Sieradzan A., Karczyńska A., Iwaszkiewicz J., Cesson V., Węgrzyn K., Zhukov I., Maszota-Zieleniak M., Michielin O. et al., 2020/01/18. International journal of molecular sciences, 21 (2). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_A28A31EE871C]
Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized <sup>13</sup>C magnetic resonance.
Can E., Mishkovsky M., Yoshihara HAI, Kunz N., Couturier D.L., Petrausch U., Doucey M.A., Comment A., 2020/01/13. Scientific reports, 10 (1) p. 200. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_3D4D5F06B036]
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation.
Hämälistö S., Stahl J.L., Favaro E., Yang Q., Liu B., Christoffersen L., Loos B., Guasch Boldú C., Joyce J.A., Reinheckel T. et al., 2020/01/13. Nature communications, 11 (1) p. 229. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_61F53FCBFD55]
Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβ.
Germann M., Zangger N., Sauvain M.O., Sempoux C., Bowler A.D., Wirapati P., Kandalaft L.E., Delorenzi M., Tejpar S., Coukos G. et al., 2020/01/09. EMBO molecular medicine, 12 (1) pp. e10681. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F06A8D6CE8D2]
A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community).
Orengo C., Velankar S., Wodak S., Zoete V., Bonvin AMJJ, Elofsson A., Feenstra K.A., Gerloff D.L., Hamelryck T., Hancock J.M. et al., 2020. F1000Research, 9. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_7E6BA5C7154A]
 
A roadmap for the next decade in cancer research.
Bernards R., Jaffee E., Joyce J.A., Lowe S.W., Mardis E.R., Morrison S.J., Polyak K., Sears C.L., Vousden K.H., Zhang Z., 2020/01. Nature cancer, 1 (1) pp. 12-17. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CC9E6CB7205D]
 
Assessment of memory formation by metabolically engineered antigen-specific CD8 T cells.
Wenes M., Romero P., Zhang L., 2020. Methods in enzymology, 631 pp. 77-90. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_63A6DEA3E726]
Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference.
Marino F., Semilietof A., Michaux J., Pak H.S., Coukos G., Müller M., Bassani-Sternberg M., 2020. Frontiers in immunology, 11 p. 1981. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E06D274ABF64]
Cancer and HIV-1 Infection: Patterns of Chronic Antigen Exposure.
Vigano S., Bobisse S., Coukos G., Perreau M., Harari A., 2020. Frontiers in immunology, 11 p. 1350. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_19C82F6CB34E]
Charting the immune landscape in brain cancers
Soukup Klara, Joyce Johanna, 2020. TheScienceBreaker.
[URN][DOI][serval:BIB_BAB9056856AB]
 
Classifying dementia progression using microbial profiling of saliva.
Bathini P., Foucras S., Dupanloup I., Imeri H., Perna A., Berruex J.L., Doucey M.A., Annoni J.M., Auber Alberi L., 2020. Alzheimer's & dementia, 12 (1) pp. e12000. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D08E4B7845AF]
Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq
Carmona Santiago J., Siddiqui Imran, Bilous Mariia, Held Werner, Gfeller David, 2020/01/01. OncoImmunology, 9 (1) p. 1737369. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EDA6E7092CF7]
 
Detecting and analyzing murine innate lymphoid cells.
Gomez-Cadena A., Romero P., Trabanelli S., Jandus C., 2020. Methods in enzymology, 631 pp. 329-342. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_91629D320BEA]
Durable response to palbociclib and letrozole in ovarian cancer with CDKN2A loss.
Frisone D., Charrier M., Clement S., Christinat Y., Thouvenin L., Homicsko K., Michielin O., Bodmer A., Chappuis P.O., McKee T.A. et al., 2020. Cancer biology & therapy, 21 (3) pp. 197-202. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DDF548EFECDC]
Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells.
Martinez-Usatorre A., Carmona S.J., Godfroid C., Yacoub Maroun C., Labiano S., Romero P., 2020. Frontiers in immunology, 11 p. 340. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8D693EC9FE6D]
 
EPIC: A Tool to Estimate the Proportions of Different Cell Types from Bulk Gene Expression Data
Racle Julien, Gfeller David, 2020. pp. 233-248 dans Bioinformatics for Cancer Immunotherapy, Springer US.
[DOI][WoS][Pmid][serval:BIB_AF1B21C1943C]
 
High-throughput identification of human antigen-specific CD8<sup>+</sup> and CD4<sup>+</sup> T cells using soluble pMHC multimers.
Magnin M., Guillaume P., Coukos G., Harari A., Schmidt J., 2020. Methods in enzymology, 631 pp. 21-42. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FD66E29F7790]
 
Immunity, Hypoxia, and Metabolism-the Ménage à Trois of Cancer: Implications for Immunotherapy.
Riera-Domingo C., Audigé A., Granja S., Cheng W.C., Ho P.C., Baltazar F., Stockmann C., Mazzone M., 2020/01/01. Physiological reviews, 100 (1) pp. 1-102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6448AD630AF8]
LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures.
Gestermann N., Saugy D., Martignier C., Tillé L., Fuertes Marraco S.A., Zettl M., Tirapu I., Speiser D.E., Verdeil G., 2020. Oncoimmunology, 9 (1) p. 1736792. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FD23668D4829]
Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal.
Bianchi V., Harari A., Coukos G., 2020. Frontiers in immunology, 11 p. 1215. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B0551F2A3933]
 
Novel Strategies of Anti-Tumor Vaccines
Bassani Sternberg Michal, 2020., Frontiers Media SA.
[DOI][serval:BIB_B78B3712DBD3]
Off-the-Shelf Allogeneic T Cell Therapies for Cancer: Opportunities and Challenges Using Naturally Occurring "Universal" Donor T Cells.
Perez C., Gruber I., Arber C., 2020. Frontiers in immunology, 11 p. 583716. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_812C7CDE2860]
Predicting combinations of immunomodulators to enhance dendritic cell-based vaccination based on a hybrid experimental and computational platform.
Ahmed R., Crespo I., Tuyaerts S., Bekkar A., Graciotti M., Xenarios I., Kandalaft L.E., 2020. Computational and structural biotechnology journal, 18 pp. 2217-27. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2B3CB067B0E1]
Reporting Guidelines, Review of Methodological Standards, and Challenges Toward Harmonization in Bone Marrow Adiposity Research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society.
Tratwal J., Labella R., Bravenboer N., Kerckhofs G., Douni E., Scheller E.L., Badr S., Karampinos D.C., Beck-Cormier S., Palmisano B. et al., 2020. Frontiers in endocrinology, 11 p. 65. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8788C3545470]
2019
 
Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry.
Girotra M., Thierry A.C., Harari A., Coukos G., Naveiras O., Vannini N., 2019/12/26. Journal of visualized experiments 154. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DE9A27B5B4E4]
Microfluidic device performing on flow study of serial cell-cell interactions of two cell populations.
Duchamp M., Dahoun T., Vaillier C., Arnaud M., Bobisse S., Coukos G., Harari A., Renaud P., 2019/12/09. RSC advances, 9 (70) pp. 41066-41073. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2E280C4A083E]
 
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8<sup>+</sup> T-cell Responses.
Liu Y., Cuendet M.A., Goffin L., Šachl R., Cebecauer M., Cariolato L., Guillaume P., Reichenbach P., Irving M., Coukos G. et al., 2019/12/06. Journal of molecular biology, 431 (24) pp. 4941-4958. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7D824F910BFC]
 
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis.
Dafni U., Michielin O., Lluesma S.M., Tsourti Z., Polydoropoulou V., Karlis D., Besser M.J., Haanen J., Svane I.M., Ohashi P.S. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1902-1913. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DF9E566FB280]
 
Gender medicine and oncology: report and consensus of an ESMO workshop.
Wagner A.D., Oertelt-Prigione S., Adjei A., Buclin T., Cristina V., Csajka C., Coukos G., Dafni U., Dotto G.P., Ducreux M. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1914-1924. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C7C76EA90383]
Herpes simplex encephalitis in adult patients with MASP-2 deficiency.
Bibert S., Piret J., Quinodoz M., Collinet E., Zoete V., Michielin O., Menasria R., Meylan P., Bihl T., Erard V. et al., 2019/12. PLoS pathogens, 15 (12) pp. e1008168. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_568322E0BDD0]
 
The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies.
Jandus P., Boligan K.F., Smith D.F., de Graauw E., Grimbacher B., Jandus C., Abdelhafez M.M., Despont A., Bovin N., Simon D. et al., 2019/11/28. Blood, 134 (22) pp. 1941-1950. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_81D29BA86AAD]
 
Evaluating Magnetic Resonance Spectroscopy as a Tool for Monitoring Therapeutic Response of Whole Brain Radiotherapy in a Mouse Model for Breast-to-Brain Metastasis.
Chae W.H., Niesel K., Schulz M., Klemm F., Joyce J.A., Prümmer M., Brill B., Bergs J., Rödel F., Pilatus U. et al., 2019/11/27. Frontiers in oncology, 9 p. 1324. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_22B16FC3657F]
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma.
Sarivalasis A., Boudousquié C., Balint K., Stevenson B.J., Gannon P.O., Iancu E.M., Rossier L., Martin Lluesma S., Mathevet P., Sempoux C. et al., 2019/11/26. Journal of translational medicine, 17 (1) p. 391. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_313F7CD9FDBC]
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML.
Salomé B., Gomez-Cadena A., Loyon R., Suffiotti M., Salvestrini V., Wyss T., Vanoni G., Ruan D.F., Rossi M., Tozzo A. et al., 2019/11/26. Blood advances, 3 (22) pp. 3674-3687. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BC26C680B22]
Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment.
Newey A., Griffiths B., Michaux J., Pak H.S., Stevenson B.J., Woolston A., Semiannikova M., Spain G., Barber L.J., Matthews N. et al., 2019/11/18. Journal for immunotherapy of cancer, 7 (1) p. 309. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7418AE3DFDA7]
Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes.
Duong M.N., Erdes E., Hebeisen M., Rufer N., 2019/11/05. Journal for immunotherapy of cancer, 7 (1) p. 284. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F1677E168BF3]
 
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes.
Racle J., Michaux J., Rockinger G.A., Arnaud M., Bobisse S., Chong C., Guillaume P., Coukos G., Harari A., Jandus C. et al., 2019/11. Nature biotechnology, 37 (11) pp. 1283-1286. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D9A8D08A5BC6]
 
The Romand Network of Oncology: bridging the gap of personalised oncology
Michielin O., Tsantoulis P., Homicsko K., Christinat Y., De Leval L., Bisig B., Missiaglia E., Zoete V., Krebs F., Fortin A. et al., 2019/10/18. Swiss Medical Weekly.
[serval:BIB_2A3947B3BCE2]
 
Radiotherapy for pelvic nodal recurrences after radical prostatectomy: patient selection in clinical practice.
Panje C., Zilli T., Pra A.D., Arnold W., Brouwer K., Garcia Schüler H.I., Gomez S., Herrera F., Khanfir K., Papachristofilou A. et al., 2019/10/16. Radiation oncology, 14 (1) p. 177. Peer-reviewed.
[DOI][Pmid][serval:BIB_3425523584B2]
 
Tape-Stripping Electrochemical Detection of Melanoma.
Darvishi S., Pick H., Lin T.E., Zhu Y., Li X., Ho P.C., Girault H.H., Lesch A., 2019/10/15. Analytical chemistry, 91 (20) pp. 12900-12908. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4B5AE89097F4]
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8<sup>+</sup> T cells.
Mastelic-Gavillet B., Navarro Rodrigo B., Décombaz L., Wang H., Ercolano G., Ahmed R., Lozano L.E., Ianaro A., Derré L., Valerio M. et al., 2019/10/10. Journal for immunotherapy of cancer, 7 (1) p. 257. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CC3C085DEA43]
 
Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Röhrig U.F., Reynaud A., Majjigapu S.R., Vogel P., Pojer F., Zoete V., 2019/10/10. Journal of medicinal chemistry, 62 (19) pp. 8784-8795. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D8CCFFB94292]
 
Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis.
Duc D., Vigne S., Bernier-Latmani J., Yersin Y., Ruiz F., Gaïa N., Leo S., Lazarevic V., Schrenzel J., Petrova T.V. et al., 2019/10/08. Cell reports, 29 (2) pp. 378-390.e4. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6227A92C8D06]
 
Fifty Shades of α-Ketoglutarate on Cellular Programming.
Di Conza G., Tsai C.H., Ho P.C., 2019/10/03. Molecular cell, 76 (1) pp. 1-3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CB375784E0F9]
 
Immunotherapy in Ovarian Cancer: Are We There Yet?
Kandalaft L.E., Odunsi K., Coukos G., 2019/09/20. Journal of clinical oncology, 37 (27) pp. 2460-2471. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1583C45E6E7E]
Application of the SwissDrugDesign Online Resources in Virtual Screening.
Daina A., Zoete V., 2019/09/18. International journal of molecular sciences, 20 (18) p. 4612. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B934FE45EAA7]
Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery.
Fierle J.K., Abram-Saliba J., Brioschi M., deTiani M., Coukos G., Dunn S.M., 2019/09/06. Scientific reports, 9 (1) p. 12815. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FCB67A02E15F]
Peripheral Innate Lymphoid Cells Are Increased in First Line Metastatic Colorectal Carcinoma Patients: A Negative Correlation With Th1 Immune Responses
Loyon Romain, Jary Marine, Salomé Bérengère, Gomez-Cadena Alejandra, Galaine Jeanne, Kroemer Marie, Romero Pedro, Trabanelli Sara, Adotévi Olivier, Borg Christophe et al., 2019/09/06. Frontiers in Immunology, 10 p. 2121. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_3FC0B4BB29C7]
 
Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance.
Martins F., Sofiya L., Sykiotis G.P., Lamine F., Maillard M., Fraga M., Shabafrouz K., Ribi C., Cairoli A., Guex-Crosier Y. et al., 2019/09. Nature reviews. Clinical oncology, 16 (9) pp. 563-580. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7F8DDEE8DA1E]
 
Biomodulina T partially restores immunosenescent CD4 and CD8 T cell compartments in the elderly.
Saavedra D., Fuertes S.A., Suárez G.M., González A., Lorenzo-Luaces P., García B., Aznar E., Mazorra Z., Crombet T., Speiser D.E. et al., 2019/09. Experimental gerontology, 124 p. 110633. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6E061DCF6353]
 
Cancer Immunotherapy: A Simple Guide for Interventional Radiologists of New Therapeutic Approaches.
Digklia A., Duran R., Homicsko K., Kandalaft L.E., Hocquelet A., Orcurto A., Coukos G., Denys A., 2019/09. Cardiovascular and interventional radiology, 42 (9) pp. 1221-1229. Peer-reviewed.
[DOI][Pmid][serval:BIB_13E5E5B29D1D]
 
Firing Up Cold Tumors.
Cheng W.C., Ho P.C., 2019/09. Trends in cancer, 5 (9) pp. 528-530. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F50ED56DE9EB]
 
Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands".
Rolfs Z., Müller M., Shortreed M.R., Smith L.M., Bassani-Sternberg M., 2019/08/16. Science immunology, 4 (38). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0BB6D028A753]
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients
Bassani-Sternberg Michal, Digklia Antonia, Huber Florian, Wagner Dorothea, Sempoux Christine, Stevenson Brian J., Thierry Anne-Christine, Michaux Justine, Pak HuiSong, Racle Julien et al., 2019/08/08. Frontiers in Immunology, 10 p. 1832. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0144F5D289B5]
 
Challenges to curing primary brain tumours.
Aldape K., Brindle K.M., Chesler L., Chopra R., Gajjar A., Gilbert M.R., Gottardo N., Gutmann D.H., Hargrave D., Holland E.C. et al., 2019/08. Nature reviews. Clinical oncology, 16 (8) pp. 509-520. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BAF957625821]
 
F-18-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer.
Jreige M., Letovanec I., Chaba K., Renaud S., Rusakiewicz S., Cristina V., Peters S., Krueger T., de Leval L., Kandalaft L.E. et al., 2019/08. European journal of nuclear medicine and molecular imaging, 46 (9) pp. 1859-1868. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F575C6723CE]
Novel inverse planning optimization algorithm for robotic radiosurgery: First clinical implementation and dosimetric evaluation.
Zeverino M., Marguet M., Zulliger C., Durham A., Jumeau R., Herrera F.G., Schiappacasse L., Bourhis J., Bochud F.O., Moeckli R., 2019/08. Physica medica, 64 pp. 230-237. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B851A13DC5B2]
Rational combinations of immunotherapy with radiotherapy in ovarian cancer.
Herrera F.G., Irving M., Kandalaft L.E., Coukos G., 2019/08. The Lancet. Oncology, 20 (8) pp. e417-e433. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B919A825548B]
 
Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'.
Aldape K., Brindle K.M., Chesler L., Chopra R., Gajjar A., Gilbert M.R., Gottardo N., Gutmann D.H., Hargrave D., Holland E.C. et al., 2019/08. Nature reviews. Clinical oncology, 16 (8) pp. 522-523. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B957A30B68EB]
 
Sculpting tumor microenvironment with immune system: from immunometabolism to immunoediting.
Yu Y.R., Ho P.C., 2019/08. Clinical and experimental immunology, 197 (2) pp. 153-160. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F2A32ECC9A7]
 
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.
Costa-Nunes C., Cachot A., Bobisse S., Arnaud M., Genolet R., Baumgaertner P., Speiser D.E., Sousa Alves P.M., Sandoval F., Adotévi O. et al., 2019/07/15. Clinical cancer research, 25 (14) pp. 4320-4331. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_99ED3D648751]
 
Multi-Panel, On-Single-Chip Memristive Biosensing
Tzouvadaki Ioulia, Tuoheti Abuduwaili, Lorrain Severine, Quadroni Manfredo, Doucey Marie-Agnes, De Micheli Giovanni, Demarchi Danilo, Carrara Sandro, 2019/07/15. IEEE Sensors Journal, 19 (14) pp. 5769-5774.
[DOI][WoS][serval:BIB_112AD9DCB24E]
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.
Ayeni D., Miller B., Kuhlmann A., Ho P.C., Robles-Oteiza C., Gaefele M., Levy S., de Miguel F.J., Perry C., Guan T. et al., 2019/07/10. Journal for immunotherapy of cancer, 7 (1) p. 172. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_765E95D84B97]
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules.
Daina A., Michielin O., Zoete V., 2019/07/02. Nucleic acids research, 47 (W1) pp. W357-W364. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_37625953AF4B]
 
Navigating metabolic pathways to enhance antitumour immunity and immunotherapy.
Li X., Wenes M., Romero P., Huang S.C., Fendt S.M., Ho P.C., 2019/07. Nature reviews. Clinical oncology, 16 (7) pp. 425-441. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F7C5AE601718]
Mass spectrometry driven exploration reveals nuances of neoepitope-driven tumor rejection.
Ebrahimi-Nik H., Michaux J., Corwin W.L., Keller G.L., Shcheglova T., Pak H., Coukos G., Baker B.M., Mandoiu I.I., Bassani-Sternberg M. et al., 2019/06/20. JCI insight, 5. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_77410C339277]
Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice
Cicone F., Gnesin S., Denoël T., Stora T., van der Meulen N.P., Müller C., Vermeulen C., Benešová M., Köster U., Johnston K. et al., 2019/06/11. EJNMMI research, 9 (1) p. 53. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_22C26DF26A4B]
Therapeutic Regeneration of Lymphatic and Immune Cell Functions upon Lympho-organoid Transplantation.
Lenti E., Bianchessi S., Proulx S.T., Palano M.T., Genovese L., Raccosta L., Spinelli A., Drago D., Andolfo A., Alfano M. et al., 2019/06/11. Stem cell reports, 12 (6) pp. 1260-1268. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_51D0703A660E]
 
Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Dangaj D., Bruand M., Grimm A.J., Ronet C., Barras D., Duttagupta P.A., Lanitis E., Duraiswamy J., Tanyi J.L., Benencia F. et al., 2019/06/10. Cancer cell, 35 (6) pp. 885-900.e10. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_95C8776874F3]
 
Bi-allelic Variants in DYNC1I2 Cause Syndromic Microcephaly with Intellectual Disability, Cerebral Malformations, and Dysmorphic Facial Features.
Ansar M., Ullah F., Paracha S.A., Adams D.J., Lai A., Pais L., Iwaszkiewicz J., Millan F., Sarwar M.T., Agha Z. et al., 2019/06/06. American journal of human genetics, 104 (6) pp. 1073-1087. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_29D795794213]
 
Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis.
Saglietti C., La Rosa S., Sykiotis G.P., Letovanec I., Bulliard J.L., Piana S., Mermod M., Petrova T., Uccella S., Sessa F. et al., 2019/06. Endocrine pathology, 30 (2) pp. 138-145. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_564B70BCE78F]
 
MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma.
Martinez-Usatorre A., Sempere L.F., Carmona S.J., Carretero-Iglesia L., Monnot G., Speiser D.E., Rufer N., Donda A., Zehn D., Jandus C. et al., 2019/06. Cancer immunology research, 7 (6) pp. 1013-1024. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4CB1877985DB]
Re-education of macrophages as a therapeutic strategy in cancer.
Kowal J., Kornete M., Joyce J.A., 2019/06. Immunotherapy, 11 (8) pp. 677-689. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7E2B9DDA760A]
 
T-cell bispecific antibodies in node-positive breast cancer: novel therapeutic avenue for MHC class I loss variants.
Messaoudene M., Mourikis T.P., Michels J., Fu Y., Bonvalet M., Lacroix-Trikki M., Routy B., Fluckiger A., Rusakiewicz S., Roberti M.P. et al., 2019/06/01. Annals of oncology, 30 (6) pp. 934-944. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BF300CC80761]
 
Tumor Landscapes: β-Catenin Drives Immune Desertification.
Dangaj D., Barras D., Coukos G., 2019/05/15. Clinical cancer research, 25 (10) pp. 2943-2945. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7529A1E77088]
Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients.
Broggi MAS, Maillat L., Clement C.C., Bordry N., Corthésy P., Auger A., Matter M., Hamelin R., Potin L., Demurtas D. et al., 2019/05/06. The Journal of experimental medicine, 216 (5) pp. 1091-1107. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_83C31BFEAA5C]
 
MALDI Detection of Exosomes: A Potential Tool for Cancer Studies
Zhu Yingdi, Pick Horst, Gasilova Natalia, Li Xiaoyun, Lin Tzu-En, Laeubli Heinz Philipp, Zippelius Alfred, Ho Ping-Chih, Girault Hubert H., 2019/05. Chem, 5 (5) pp. 1318-1336.
[DOI][WoS][serval:BIB_05812E4472A3]
 
Correction: Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Westergaard MCW, Andersen R., Chong C., Kjeldsen J.W., Pedersen M., Friese C., Hasselager T., Lajer H., Coukos G., Bassani-Sternberg M. et al., 2019/04..
[DOI][WoS][Pmid][serval:BIB_5C827EDF3F51]
 
Going Beyond the Sequences: TCR Binding Patterns at the Service of Cancer Detection.
Zoete V., Coukos G., 2019/04/01. Cancer research, 79 (7) pp. 1299-1301. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B6A2460E1FCA]
 
Publisher Correction: Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/04..
[DOI][WoS][Pmid][serval:BIB_2453C5C48240]
Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer.
Lan Q., Peyvandi S., Duffey N., Huang Y.T., Barras D., Held W., Richard F., Delorenzi M., Sotiriou C., Desmedt C. et al., 2019/04. Oncogene, 38 (15) pp. 2814-2829. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_94A8CCA9EF90]
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret C., Miah SMS, Rota G., Fonta N.P., Wang H., Held W., Birchmeier W., Sexl V., Yang W., Vivier E. et al., 2019/03/29. Nature communications, 10 (1) p. 1444. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1D70F1981844]
 
Biallelic variants in FBXL3 cause intellectual disability, delayed motor development and short stature.
Ansar M., Paracha S.A., Serretti A., Sarwar M.T., Khan J., Ranza E., Falconnet E., Iwaszkiewicz J., Shah S.F., Qaisar A.A. et al., 2019/03/15. Human molecular genetics, 28 (6) pp. 972-979. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CC3DB25E32E9]
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Vannini N., Campos V., Girotra M., Trachsel V., Rojas-Sutterlin S., Tratwal J., Ragusa S., Stefanidis E., Ryu D., Rainer P.Y. et al., 2019/03/07. Cell stem cell, 24 (3) pp. 405-418.e7. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9C9755E6E69D]
Differential regulation of RNA polymerase III genes during liver regeneration.
Yeganeh M., Praz V., Carmeli C., Villeneuve D., Rib L., Guex N., Herr W., Delorenzi M., Hernandez N., CycliX consortium, 2019/02/28. Nucleic Acids Research, 47 (4) pp. 1786-1796. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_014840C5C9E3]
Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides.
Bargeton B., Iwaszkiewicz J., Bonifacio G., Roy S., Zoete V., Kellenberger S., 2019/02/22. Scientific reports, 9 (1) p. 2599. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3C115A0AD37A]
Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients.
Fässler M., Diem S., Mangana J., Hasan Ali O., Berner F., Bomze D., Ring S., Niederer R., Del Carmen Gil Cruz C., Pérez Shibayama C.I. et al., 2019/02/20. Journal for immunotherapy of cancer, 7 (1) p. 50. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_98F688A29D1B]
Cytotoxic CD8<sup>+</sup> T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons.
Coque E., Salsac C., Espinosa-Carrasco G., Varga B., Degauque N., Cadoux M., Crabé R., Virenque A., Soulard C., Fierle J.K. et al., 2019/02/05. Proceedings of the National Academy of Sciences of the United States of America, 116 (6) pp. 2312-2317. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C20819493CBC]
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.
Guay C., Kruit J.K., Rome S., Menoud V., Mulder N.L., Jurdzinski A., Mancarella F., Sebastiani G., Donda A., Gonzalez B.J. et al., 2019/02/05. Cell metabolism, 29 (2) pp. 348-361.e6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_32A6AD8B1141]
50-Gy Stereotactic Body Radiation Therapy to the Dominant Intraprostatic Nodule: Results From a Phase 1a/b Trial.
Herrera F.G., Valerio M., Berthold D., Tawadros T., Meuwly J.Y., Vallet V., Baumgartner P., Thierry A.C., De Bari B., Jichlinski P. et al., 2019/02/01. International journal of radiation oncology, biology, physics, 103 (2) pp. 320-334. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8A5A6B3310C5]
Safety and Tolerability of Adoptive Cell Therapy in Cancer.
Wolf B., Zimmermann S., Arber C., Irving M., Trueb L., Coukos G., 2019/02. Drug safety, 42 (2) pp. 315-334. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_944ED4AF4291]
 
The pro- and anti-tumor role of ILC2s.
Trabanelli S., Chevalier M.F., Derré L., Jandus C., 2019/02. Seminars in immunology, 41 p. 101276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_ECAD6DCB8107]
 
To be a tumor promoting or tumor suppressing ILC: That is the question.
Jandus C., 2019/02. Seminars in immunology, 41 p. 101283. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C30202868FA3]
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Westergaard MCW, Andersen R., Chong C., Kjeldsen J.W., Pedersen M., Friese C., Hasselager T., Lajer H., Coukos G., Bassani-Sternberg M. et al., 2019/02. British journal of cancer, 120 (4) pp. 424-434. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_031BC21D26AB]
 
Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle.
Cheng W.C., Tsui Y.C., Ragusa S., Koelzer V.H., Mina M., Franco F., Läubli H., Tschumi B., Speiser D., Romero P. et al., 2019/02. Nature immunology, 20 (2) pp. 206-217. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A10BFBC01F0D]
Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Hendrikx S., Coso S., Prat-Luri B., Wetterwald L., Sabine A., Franco C.A., Nassiri S., Zangger N., Gerhardt H., Delorenzi M. et al., 2019/01/29. Cell reports, 26 (5) pp. 1227-1241.e6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B316C6C93CB8]
Imaging endogenous macrophage iron deposits reveals a metabolic biomarker of polarized tumor macrophage infiltration and response to CSF1R breast cancer immunotherapy.
Leftin A., Ben-Chetrit N., Joyce J.A., Koutcher J.A., 2019/01/29. Scientific reports, 9 (1) p. 857. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_60BF21E76912]
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I., Schaeuble K., Chennupati V., Fuertes Marraco S.A., Calderon-Copete S., Pais Ferreira D., Carmona S.J., Scarpellino L., Gfeller D., Pradervand S. et al., 2019/01/15. Immunity, 50 (1) pp. 195-211.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8DBCBF3E53B5]
A structural model of the immune checkpoint CD160-HVEM complex derived from HDX-mass spectrometry and molecular modeling.
Kuncewicz K., Spodzieja M., Sieradzan A., Karczyńska A., Dąbrowska K., Dadlez M., Speiser D.E., Derre L., Rodziewicz-Motowidło S., 2019/01/11. Oncotarget, 10 (4) pp. 536-550. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F79CFFA532C9]
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