Centre intégratif de génomique

Equipe principale | CIG Services communs | Groupe Benton | Groupe Fajas | Groupe Fankhauser | Groupe Franken | Groupe Gambetta | Groupe Gatfield | Groupe Larsch | Groupe Michalik | Groupe Reymond | Groupe Roignant | Groupe van Leeuwen | Groupe Vastenhouw | Groupe Vjestica | Plateforme de biostatistique | Plateforme Genomics Technologies Facility (GTF) | Plateforme Protein Analysis Facility (PAF)
Publications | Mémoires et thèses

La recherche avancée est accessible via Serval

Les publications peuvent être gérées en accédant à Serval via MyUnil


1739 publications

... | 2017 | 2016 | ...
PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium.
Duszka K., Oresic M., Le May C., König J., Wahli W., 2017/11/28. International journal of molecular sciences, 18 (12) pp. E2559. Peer-reviewed.
 
WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.
Kannan M., Bayam E., Wagner C., Rinaldi B., Kretz P.F., Tilly P., Roos M., McGillewie L., Bär S., Minocha S. et al., 2017/10/31. Proceedings of the National Academy of Sciences of the United States of America, 114 (44) pp. E9308-E9317. Peer-reviewed.
A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.
Iroz A., Montagner A., Benhamed F., Levavasseur F., Polizzi A., Anthony E., Régnier M., Fouché E., Lukowicz C., Cauzac M. et al., 2017/10/10. Cell reports, 21 (2) pp. 403-416. Peer-reviewed.
Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation.
Holst S.C., Sousek A., Hefti K., Saberi-Moghadam S., Buck A., Ametamey S.M., Scheidegger M., Franken P., Henning A., Seifritz E. et al., 2017/10/05. eLife, 6 pp. eLife.28751. Peer-reviewed.
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.
Macé A., Tuke M.A., Deelen P., Kristiansson K., Mattsson H., Nõukas M., Sapkota Y., Schick U., Porcu E., Rüeger S. et al., 2017/09/29. Nature communications, 8 (1) p. 744. Peer-reviewed.
Plant Strategies for Enhancing Access to Sunlight.
Fiorucci A.S., Fankhauser C., 2017/09/11. Current biology, 27 (17) pp. R931-R940. Peer-reviewed.
The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway.
Khan AUH, Allende-Vega N., Gitenay D., Gerbal-Chaloin S., Gondeau C., Vo D.N., Belkahla S., Orecchioni S., Talarico G., Bertolini F. et al., 2017/09/06. Scientific reports, 7 (1) p. 10654. Peer-reviewed.
Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree
Boeckmann Brigitte, Dylus David, Moretti Sebastien, Altenhoff Adrian, Train Clement-Marie, Kriventseva Evgenia, Bougueleret Lydie, Xenarios Ioannis, Privman Eyal, Gabaldon Toni et al., 2017/09/05..
BLADE-ON-PETIOLE proteins act in an E3 ubiquitin ligase complex to regulate PHYTOCHROME INTERACTING FACTOR 4 abundance.
Zhang B., Holmlund M., Lorrain S., Norberg M., Bakó L., Fankhauser C., Nilsson O., 2017/08/22. eLife, 6 pp. e26759. Peer-reviewed.
Comparative Genomics of Two Sequential <i>Candida glabrata</i> Clinical Isolates.
Vale-Silva L., Beaudoing E., Tran VDT, Sanglard D., 2017/08/07. G3, 7 (8) pp. 2413-2426. Peer-reviewed.
 
MsViz: A Graphical Software Tool for In-Depth Manual Validation and Quantitation of Post-translational Modifications.
Martín-Campos T., Mylonas R., Masselot A., Waridel P., Petricevic T., Xenarios I., Quadroni M., 2017/08/04. Journal of proteome research, 16 (8) pp. 3092-3101. Peer-reviewed.
 
Multisensory neural integration of chemical and mechanical signals.
Sánchez-Alcañiz J.A., Benton R., 2017/08. BioEssays, 39 (8) p. 1700060. Peer-reviewed.
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
McDaid A.F., Joshi P.K., Porcu E., Komljenovic A., Li H., Sorrentino V., Litovchenko M., Bevers RPJ, Rüeger S., Reymond A. et al., 2017/07/27. Nature communications, 8 p. 15842. Peer-reviewed.
High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci.
Gloss B.S., Signal B., Cheetham S.W., Gruhl F., Kaczorowski D.C., Perkins A.C., Dinger M.E., 2017/07/27. Scientific reports, 7 (1) p. 6731. Peer-reviewed.
Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation.
Gouge J., Guthertz N., Kramm K., Dergai O., Abascal-Palacios G., Satia K., Cousin P., Hernandez N., Grohmann D., Vannini A., 2017/07/25. Nature communications, 8 (1) p. 130. Peer-reviewed.
Studies of global and local entanglements of individual protein chains using the concept of knotoids.
Goundaroulis D., Dorier J., Benedetti F., Stasiak A., 2017/07/24. Scientific reports, 7 (1) p. 6309. Peer-reviewed.
Local auxin production underlies a spatially restricted neighbor-detection response in <i>Arabidopsis</i>.
Michaud O., Fiorucci A.S., Xenarios I., Fankhauser C., 2017/07/11. Proceedings of the National Academy of Sciences of the United States of America, 114 (28) pp. 7444-7449. Peer-reviewed.
 
Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need.
Vassalli A., Franken P., 2017/07/03. Proceedings of the National Academy of Sciences of the United States of America, 114 (27) pp. E5464-E5473. Peer-reviewed.
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
Dayon L., Guiraud S.P., Corthésy J., Da Silva L., Migliavacca E., Tautvydaitė D., Oikonomidi A., Moullet B., Henry H., Métairon S. et al., 2017/06/17. Alzheimer's research & therapy, 9 (1) p. 43. Peer-reviewed.
Ionotropic Receptor-dependent moist and dry cells control hygrosensation in Drosophila.
Knecht Z.A., Silbering A.F., Cruz J., Yang L., Croset V., Benton R., Garrity P.A., 2017/06/16. eLife, 6 pp. e26654. Peer-reviewed.
Translational contributions to tissue specificity in rhythmic and constitutive gene expression.
Castelo-Szekely V., Arpat A.B., Janich P., Gatfield D., 2017/06/16. Genome biology, 18 (1) p. 116. Peer-reviewed.
 
Behavioural characterization of AnkyrinG deficient mice, a model for ANK3 related disorders.
van der Werf I.M., Van Dam D., Missault S., Yalcin B., De Deyn P.P., Vandeweyer G., Kooy R.F., 2017/06/15. Behavioural brain research, 328 pp. 218-226. Peer-reviewed.
Diurnal regulation of RNA polymerase III transcription is under the control of both the feeding-fasting response and the circadian clock.
Mange F., Praz V., Migliavacca E., Willis I.M., Schütz F., Hernandez N., CycliX Consortium, 2017/06. Genome research, 27 (6) pp. 973-984. Peer-reviewed.
 
Rare missense mutations in P2RY11 in narcolepsy with cataplexy.
Degn M., Dauvilliers Y., Dreisig K., Lopez R., Pfister C., Pradervand S., Rahbek Kornum B., Tafti M., 2017/06/01. Brain, 140 (6) pp. 1657-1668. Peer-reviewed.
Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats.
Rafie K., Raimi O., Ferenbach A.T., Borodkin V.S., Kapuria V., van Aalten DMF, 2017/06. Open biology, 7 (6) p. 170078. Peer-reviewed.
 
Tracking the Evolution of Non-Small-Cell Lung Cancer.
Jamal-Hanjani M., Wilson G.A., McGranahan N., Birkbak N.J., Watkins TBK, Veeriah S., Shafi S., Johnson D.H., Mitter R., Rosenthal R. et al., 2017/06/01. The New England journal of medicine, 376 (22) pp. 2109-2121. Peer-reviewed.
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
Abbosh Christopher, Birkbak Nicolai J., Wilson Gareth A., Jamal-Hanjani Mariam, Constantin Tudor, Salari Raheleh, Le Quesne John, Moore David A., Veeriah Selvaraju, Rosenthal Rachel et al., 2017/05/25. Nature, 545 (7655) pp. 446-451.
 
AoS28D, a proline-Xaa carboxypeptidase secreted by Aspergillus oryzae.
Salamin K., Eugster P.J., Jousson O., Waridel P., Grouzmann E., Monod M., 2017/05. Applied microbiology and biotechnology, 101 (10) pp. 4129-4137. Peer-reviewed.
 
Deletion of Xenotropic and Polytropic Retrovirus Receptor 1 in mouse nephron causes renal Fanconi syndrome and hypophosphatemic rickets [857.9]
Ansermet C., Moor M., Centeno G., Auberson M., Hu D., Barron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04/30., Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting pp. n.p. dans Faseb Journal.
β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.
Somm E., Henry H., Bruce S.J., Aeby S., Rosikiewicz M., Sykiotis G.P., Asrih M., Jornayvaz F.R., Denechaud P.D., Albrecht U. et al., 2017/04/20. JCI insight, 2 (8). Peer-reviewed.
 
Measurement of narcolepsy symptoms: The Narcolepsy Severity Scale.
Dauvilliers Y., Beziat S., Pesenti C., Lopez R., Barateau L., Carlander B., Luca G., Tafti M., Morin C.M., Billiard M. et al., 2017/04/04. Neurology, 88 (14) pp. 1358-1365. Peer-reviewed.
 
Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group.
Barazzoni R., Deutz NEP, Biolo G., Bischoff S., Boirie Y., Cederholm T., Cuerda C., Delzenne N., Leon Sanz M., Ljungqvist O. et al., 2017/04. Clinical nutrition, 36 (2) pp. 355-363. Peer-reviewed.
Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for <i>Elovl2</i> in glucose-induced insulin secretion.
Cruciani-Guglielmacci C., Bellini L., Denom J., Oshima M., Fernandez N., Normandie-Levi P., Berney X.P., Kassis N., Rouch C., Dairou J. et al., 2017/04. Molecular metabolism, 6 (4) pp. 340-351. Peer-reviewed.
Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron.
Ansermet C., Moor M.B., Centeno G., Auberson M., Hu D.Z., Baron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04. Journal of the American Society of Nephrology : JASN, 28 (4) pp. 1073-1078. Peer-reviewed.
Second-Generation Drosophila Chemical Tags: Sensitivity, Versatility, and Speed.
Sutcliffe B., Ng J., Auer T.O., Pasche M., Benton R., Jefferis G.S., Cachero S., 2017/04. Genetics, 205 (4) pp. 1399-1408. Peer-reviewed.
 
The neurobiology of gustation in insect disease vectors: progress and potential.
Benton R., 2017/04. Current opinion in insect science, 20 pp. 19-27. Peer-reviewed.
 
Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells.
Rodrigues A.R., Yakushiji-Kaminatsui N., Atsuta Y., Andrey G., Schorderet P., Duboule D., Tabin C.J., 2017/03/21. Proceedings of the National Academy of Sciences of the United States of America, 114 (12) pp. 3139-3144. Peer-reviewed.
Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.
Wigger L., Cruciani-Guglielmacci C., Nicolas A., Denom J., Fernandez N., Fumeron F., Marques-Vidal P., Ktorza A., Kramer W., Schulte A. et al., 2017/02/28. Cell reports, 18 (9) pp. 2269-2279. Peer-reviewed.
Climbing favours the tripod gait over alternative faster insect gaits.
Ramdya P., Thandiackal R., Cherney R., Asselborn T., Benton R., Ijspeert A.J., Floreano D., 2017/02/17. Nature communications, 8 p. 14494. Peer-reviewed.
 
Regulatory properties of statins and rho gtpases prenylation inhibitiors to stimulate melanoma immunogenicity and promote anti-melanoma immune response.
Sarrabayrouse G., Pich C., Teiti I., Tilkin-Mariame A.F., 2017/02/15. International journal of cancer, 140 (4) pp. 747-755. Peer-reviewed.
Diversity and regulatory impact of copy number variation in the primate Macaca fascicularis.
Gschwind A.R., Singh A., Certa U., Reymond A., Heckel T., 2017/02/10. BMC genomics, 18 (1) p. 144. Peer-reviewed.
 
Evolution of Acid-Sensing Olfactory Circuits in Drosophilids.
Prieto-Godino L.L., Rytz R., Cruchet S., Bargeton B., Abuin L., Silbering A.F., Ruta V., Dal Peraro M., Benton R., 2017/02/08. Neuron, 93 (3) pp. 661-676.e6. Peer-reviewed.
 
Sleep characteristics and cognitive impairment in the general population: The HypnoLaus study.
Haba-Rubio J., Marti-Soler H., Tobback N., Andries D., Marques-Vidal P., Waeber G., Vollenweider P., von Gunten A., Preisig M., Castelao E. et al., 2017/01/31. Neurology, 88 (5) pp. 463-469. Peer-reviewed.
A mechanosensory receptor required for food texture detection in Drosophila.
Sánchez-Alcañiz J.A., Zappia G., Marion-Poll F., Benton R., 2017/01/27. Nature communications, 8 p. 14192. Peer-reviewed.
ERK signaling pathway regulates sleep duration through activity-induced gene expression during wakefulness.
Mikhail C., Vaucher A., Jimenez S., Tafti M., 2017/01/24. Science signaling, 10 (463) p. 463. Peer-reviewed.
Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast.
Jeffares D.C., Jolly C., Hoti M., Speed D., Shaw L., Rallis C., Balloux F., Dessimoz C., Bähler J., Sedlazeck F.J., 2017/01/24. Nature communications, 8 p. 14061. Peer-reviewed.
UV-B Perceived by the UVR8 Photoreceptor Inhibits Plant Thermomorphogenesis.
Hayes S., Sharma A., Fraser D.P., Trevisan M., Cragg-Barber C.K., Tavridou E., Fankhauser C., Jenkins G.I., Franklin K.A., 2017/01/09. Current biology, 27 (1) pp. 120-127. Peer-reviewed.
A Gene Ontology Tutorial in Python.
Vesztrocy A.W., Dessimoz C., 2017. Methods in molecular biology, 1446 pp. 221-229. Peer-reviewed.
 
A New Split Hand/Foot Malformation with Long Bone Deficiency Familial Case.
Fusco C., Nittis P., Alfaiz A.A., Pellico M.T., Augello B., Malerba N., Zelante L., Reymond A., Merla G., 2017. Journal of Pediatric Genetics, 6 (2) pp. 98-102. Peer-reviewed.
A transcribed enhancer dictates mesendoderm specification in pluripotency.
Alexanian M., Maric D., Jenkinson S.P., Mina M., Friedman C.E., Ting C.C., Micheletti R., Plaisance I., Nemir M., Maison D. et al., 2017. Nature Communications, 8 (1) p. 1806. Peer-reviewed.
 
Alain Ktorza, PhD in Memoriam
Thorens B., Accili D., Ahrén B., Boitard C., Seino S., Cerasi E., 2017. Diabetes, Obesity & Metabolism, 19 (Suppl 1) p. 3. Peer-reviewed.
Caloric dose-responsive genes in blood cells differentiate the metabolic status of obese men.
Gille D., Zangger N., Soneson C., Bütikofer U., Delorenzi M., Schwander F., Kopf-Bolanz K.A., Chollet M., Walther B., Laederach K. et al., 2017. The Journal of Nutritional Biochemistry, 43 pp. 156-165. Peer-reviewed.
Cancer: Linking Powerhouses to Suicidal Bags.
Martinez-Carreres L., Nasrallah A., Fajas L., 2017. Frontiers in Oncology, 7 p. 204. Peer-reviewed.
 
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia I.C., Lagarrigue S., Giralt A., Martinez-Carreres L., Zanou N., Denechaud P.D., Castillo-Armengol J., Chavey C., Orpinell M., Delacuisine B. et al., 2017. Molecular Cell, 68 (2) pp. 336-349.e6. Peer-reviewed.
 
Centromere Destiny in Dicentric Chromosomes: New Insights from the Evolution of Human Chromosome 2 Ancestral Centromeric Region.
Chiatante G., Giannuzzi G., Calabrese F.M., Eichler E.E., Ventura M., 2017. Molecular Biology and Evolution, 34 (7) pp. 1669-1681. Peer-reviewed.
Chemical crosslinking and mass spectrometry to elucidate the topology of integral membrane proteins.
Debelyy M.O., Waridel P., Quadroni M., Schneiter R., Conzelmann A., 2017. PLoS One, 12 (10) pp. e0186840. Peer-reviewed.
Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes.
Loviglio M.N., Leleu M., Männik K., Passeggeri M., Giannuzzi G., van der Werf I., Waszak S.M., Zazhytska M., Roberts-Caldeira I., Gheldof N. et al., 2017. Molecular Psychiatry, 22 (6) pp. 836-849. Peer-reviewed.
 
Combined Experimental and Computational Approaches Reveal Distinct pH Dependence of Pectin Methylesterase Inhibitors.
Hocq L., Sénéchal F., Lefebvre V., Lehner A., Domon J.M., Mollet J.C., Dehors J., Pageau K., Marcelo P., Guérineau F. et al., 2017. Plant Physiology, 173 (2) pp. 1075-1093. Peer-reviewed.
Comparative genomics reveals contraction in olfactory receptor genes in bats.
Tsagkogeorga G., Müller S., Dessimoz C., Rossiter S.J., 2017. Scientific Reports, 7 (1) p. 259. Peer-reviewed.
Crucial roles of Pox neuro in the developing ellipsoid body and antennal lobes of the Drosophila brain.
Minocha S., Boll W., Noll M., 2017. PLoS One, 12 (4) pp. e0176002. Peer-reviewed.
Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome.
Gunbin K., Peshkin L., Popadin K., Annis S., Ackermann R.R., Khrapko K., 2017. Data in Brief, 13 pp. 536-544. Peer-reviewed.
 
Development of Circadian Sleep Regulation in the Rat: A Longitudinal Study Under Constant Conditions.
Frank M.G., Ruby N.F., Heller H.C., Franken P., 2017. Sleep, 40 (3) pp. PII zsw077. Peer-reviewed.
 
Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles.
Sinturel F., Gerber A., Mauvoisin D., Wang J., Gatfield D., Stubblefield J.J., Green C.B., Gachon F., Schibler U., 2017. Cell, 169 (4) pp. 651-663.e14. Peer-reviewed.
E2F1, a Novel Regulator of Metabolism.
Denechaud P.D., Fajas L., Giralt A., 2017. Frontiers in endocrinology, 8 p. 311. Peer-reviewed.
Editorial: Metabolic Adaptation to Cell Growth and Proliferation in Normal and Pathological Conditions.
Giralt A., Fajas L., 2017. Frontiers in Endocrinology, 8 p. 362. Peer-reviewed.
Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms
Presotto D., Erdes E., Duong M.N., Allard M., Regamey P.O., Quadroni M., Doucey M.A., Rufer N., Hebeisen M., 2017. Frontiers in Immunology, 8 p. 1564. Peer-reviewed.
FlyLimbTracker: An active contour based approach for leg segment tracking in unmarked, freely behaving Drosophila.
Uhlmann V., Ramdya P., Delgado-Gonzalo R., Benton R., Unser M., 2017. PLoS One, 12 (4) pp. e0173433. Peer-reviewed.
 
From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions.
Caputo T., Gilardi F., Desvergne B., 2017. FEBS Letters, 591 (19) pp. 3061-3088. Peer-reviewed.
Gene Ontology: Pitfalls, Biases, and Remedies.
Gaudet P., Dessimoz C., 2017. Methods in molecular biology, 1446 pp. 189-205. Peer-reviewed.
 
Genetics and Genomic basis of sleep in rodents
O'Hara Bruce F., Jiang Peng, Turek Fred W., Franken Paul, 2017/01/01. pp. 296-309 dans Principles and Practice of Sleep Medicine chap. 29, Elesevier-Saunders.
 
Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.
Morzyglod L., Caüzac M., Popineau L., Denechaud P.D., Fajas L., Ragazzon B., Fauveau V., Planchais J., Vasseur-Cognet M., Fartoux L. et al., 2017. Hepatology, 65 (4) pp. 1352-1368. Peer-reviewed.
Guidelines for Genome-Scale Analysis of Biological Rhythms.
Hughes M.E., Abruzzi K.C., Allada R., Anafi R., Arpat A.B., Asher G., Baldi P., de Bekker C., Bell-Pedersen D., Blau J. et al., 2017. Journal of Biological Rhythms, 32 (5) pp. 380-393. Peer-reviewed.
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.
Ferrari A., Longo R., Fiorino E., Silva R., Mitro N., Cermenati G., Gilardi F., Desvergne B., Andolfo A., Magagnotti C. et al., 2017. Nature Communications, 8 (1) p. 93. Peer-reviewed.
 
Hippo Reprograms the Transcriptional Response to Ras Signaling.
Pascual J., Jacobs J., Sansores-Garcia L., Natarajan M., Zeitlinger J., Aerts S., Halder G., Hamaratoglu F., 2017. Developmental Cell, 42 (6) pp. 667-680.e4. Peer-reviewed.
 
Hyperplectonemes: A Higher Order Compact and Dynamic DNA Self-Organization.
Japaridze A., Muskhelishvili G., Benedetti F., Gavriilidou A.F., Zenobi R., De Los Rios P., Longo G., Dietler G., 2017. Nano Letters, 17 (3) pp. 1938-1948. Peer-reviewed.
 
Inflammatory myopathy in a patient with Aicardi-Goutières syndrome.
Tumienė B., Voisin N., Preikšaitienė E., Petroška D., Grikinienė J., Samaitienė R., Utkus A., Reymond A., Kučinskas V., 2017. European Journal of Medical Genetics, 60 (3) pp. 154-158. Peer-reviewed.
 
Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis.
Gunbin K., Peshkin L., Popadin K., Annis S., Ackermann R.R., Khrapko K., 2017. Mitochondrion, 34 pp. 20-23. Peer-reviewed.
 
MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration.
San-Jose L.M., Ducrest A.L., Ducret V., Simon C., Richter H., Wakamatsu K., Roulin A., 2017/01. Molecular ecology, 26 (1) pp. 259-276. Peer-reviewed.
 
Molecular Dynamics Simulation of Supercoiled, Knotted, and Catenated DNA Molecules, Including Modeling of Action of DNA Gyrase.
Racko D., Benedetti F., Dorier J., Burnier Y., Stasiak A., 2017. Methods in Molecular Biology, 1624 pp. 339-372. Peer-reviewed.
Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.
Toffoli B., Gilardi F., Winkler C., Soderberg M., Kowalczuk L., Arsenijevic Y., Bamberg K., Bonny O., Desvergne B., 2017. PLoS One, 12 (2) pp. e0171474. Peer-reviewed.
Neuregulin 3 Mediates Cortical Plate Invasion and Laminar Allocation of GABAergic Interneurons
Bartolini G., Sánchez-Alcañiz J. A, Osório C., Valiente M., García-Frigola C, Marín O., 2017. Cell reports, 18 (5) pp. 1157-1170. Peer-reviewed.
Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.
Wang J., Mauvoisin D., Martin E., Atger F., Galindo A.N., Dayon L., Sizzano F., Palini A., Kussmann M., Waridel P. et al., 2017. Cell Metabolism, 25 (1) pp. 102-117. Peer-reviewed.
Open questions: Tackling Darwin's "instincts": the genetic basis of behavioral evolution.
Arguello J.R., Benton R., 2017. BMC Biology, 15 (1) p. 26. Peer-reviewed.
Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference
Train C.-M., Glover N.M., Gonnet G.H., Altenhoff A.M., Dessimoz C., 2017. Bioinformatics, 33 (14) pp. i75-i82.
 
Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.
Dror E., Dalmas E., Meier D.T., Wueest S., Thévenet J., Thienel C., Timper K., Nordmann T.M., Traub S., Schulze F. et al., 2017. Nature Immunology, 18 (3) pp. 283-292. Peer-reviewed.
Primer on the Gene Ontology.
Gaudet P., Škunca N., Hu J.C., Dessimoz C., 2017. Methods in molecular biology, 1446 pp. 25-37. Peer-reviewed.
Rai1 frees mice from the repression of active wake behaviors by light.
Diessler S., Kostic C., Arsenijevic Y., Kawasaki A., Franken P., 2017. eLife, 6 pp. e23292. Peer-reviewed.
 
Roles of Peroxisome Proliferator-Activated Receptor β/δ in skeletal muscle physiology.
Manickam R., Wahli W., 2017. Biochimie, 136 pp. 42-48. Peer-reviewed.
Segregated hepatocyte proliferation and metabolic states within the regenerating mouse liver.
Minocha S., Villeneuve D., Rib L., Moret C., Guex N., Herr W., 2017. Hepatology Communications, 1 (9) pp. 871-885. Peer-reviewed.
 
Survey of Global Genetic Diversity Within the Drosophila Immune System.
Early A.M., Arguello J.R., Cardoso-Moreira M., Gottipati S., Grenier J.K., Clark A.G., 2017. Genetics, 205 (1) pp. 353-366. Peer-reviewed.
 
Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome.
Tan C.K., Zhuang Y., Wahli W., 2017. Expert Opinion on Therapeutic Targets, 21 (3) pp. 333-348. Peer-reviewed.
The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes.
Djenoune L., Desban L., Gomez J., Sternberg J.R., Prendergast A., Langui D., Quan F.B., Marnas H., Auer T.O., Rio J.P. et al., 2017. Scientific Reports, 7 (1) p. 719. Peer-reviewed.
 
The Gene Ontology Handbook
Dessimoz Christophe, Škunca Nives (eds.)Dessimoz Christophe, 2017., Springer New York.
 
The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVs.
Loviglio M.N., Arbogast T., Jønch A.E., Collins S.C., Popadin K., Bonnet C.S., Giannuzzi G., Maillard A.M., Jacquemont S., 16p11.2 Consortium et al., 2017. American Journal of Human Genetics, 101 (4) pp. 564-577. Peer-reviewed.
 
The influence of greenhouse-integrated photovoltaics on crop production
Allardyce C.S., Fankhauser C., Zakeeruddin S.M., Grätzel M., Dyson P.J., 2017. Solar Energy, 155 pp. 517-522. Peer-reviewed.
The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and Caenorhabditis elegans.
Maia Chagas A., Prieto-Godino L.L., Arrenberg A.B., Baden T., 2017. PLoS Biology, 15 (7) pp. e2002702. Peer-reviewed.
Topological Models for Open-Knotted Protein Chains Using the Concepts of Knotoids and Bonded Knotoids
Goundaroulis D., Gügümcü N., Lambropoulou S., Dorier J., Stasiak A., Kauffman L., 2017. Polymers, 9 (9) p. 444. Peer-reviewed.
Transcription-induced supercoiling explains formation of self-interacting chromatin domains in S. pombe.
Benedetti F., Racko D., Dorier J., Burnier Y., Stasiak A., 2017. Nucleic Acids Research, 45 (17) pp. 9850-9859. Peer-reviewed.
Transcriptional interference by RNA polymerase III affects expression of the Polr3e gene.
Yeganeh M., Praz V., Cousin P., Hernandez N., 2017. Genes and Development, 31 (4) pp. 413-421. Peer-reviewed.
Transcriptional regulatory logic of the diurnal cycle in the mouse liver.
Sobel J.A., Krier I., Andersin T., Raghav S., Canella D., Gilardi F., Kalantzi A.S., Rey G., Weger B., Gachon F. et al., 2017. PLoS biology, 15 (4) pp. e2001069. Peer-reviewed.
tRNA biology in the omics era: Stress signalling dynamics and cancer progression.
Orioli A., 2017. BioEssays, 39 (3) p. 1. Peer-reviewed.
Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.
Ginster S., Bardet M., Unterreiner A., Malinverni C., Renner F., Lam S., Freuler F., Gerrits B., Voshol J., Calzascia T. et al., 2017. PLoS One, 12 (1) pp. e0169026. Peer-reviewed.
Integration of Phytochrome and Cryptochrome Signals Determines Plant Growth during Competition for Light.
de Wit M., Keuskamp D.H., Bongers F.J., Hornitschek P., Gommers CMM, Reinen E., Martínez-Cerón C., Fankhauser C., Pierik R., 2016/12/19. Current biology, 26 (24) pp. 3320-3326. Peer-reviewed.
Shade Promotes Phototropism through Phytochrome B-Controlled Auxin Production.
Goyal A., Karayekov E., Galvão V.C., Ren H., Casal J.J., Fankhauser C., 2016/12/19. Current biology, 26 (24) pp. 3280-3287. Peer-reviewed.
A molecular and neuronal basis for amino acid sensing in the Drosophila larva.
Croset V., Schleyer M., Arguello J.R., Gerber B., Benton R., 2016/12/16. Scientific reports, 6 p. 34871. Peer-reviewed.
 
LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans.
Tan S., Cardoso-Moreira M., Shi W., Zhang D., Huang J., Mao Y., Jia H., Zhang Y., Chen C., Shao Y. et al., 2016/12. Genome research, 26 (12) pp. 1663-1675. Peer-reviewed.
Neighbor Detection Induces Organ-Specific Transcriptomes, Revealing Patterns Underlying Hypocotyl-Specific Growth.
Kohnen M.V., Schmid-Siegert E., Trevisan M., Petrolati L.A., Sénéchal F., Müller-Moulé P., Maloof J., Xenarios I., Fankhauser C., 2016/12. The Plant cell, 28 (12) pp. 2889-2904. Peer-reviewed.
Oral transfer of chemical cues, growth proteins and hormones in social insects.
LeBoeuf A.C., Waridel P., Brent C.S., Gonçalves A.N., Menin L., Ortiz D., Riba-Grognuz O., Koto A., Soares Z.G., Privman E. et al., 2016/11/29. eLife, 5 pp. e20375. Peer-reviewed.
Homeostasis Meets Motivation in the Battle to Control Food Intake.
Ferrario C.R., Labouèbe G., Liu S., Nieh E.H., Routh V.H., Xu S., O'Connor E.C., 2016/11/09. The Journal of neuroscience, 36 (45) pp. 11469-11481. Peer-reviewed.
A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion.
Picard A., Soyer J., Berney X., Tarussio D., Quenneville S., Jan M., Grouzmann E., Burdet F., Ibberson M., Thorens B., 2016/11/08. Cell reports, 17 (7) pp. 1795-1806. Peer-reviewed.
Olfactory receptor pseudo-pseudogenes.
Prieto-Godino L.L., Rytz R., Bargeton B., Abuin L., Arguello J.R., Peraro M.D., Benton R., 2016/11/03. Nature, 539 (7627) pp. 93-97. Peer-reviewed.
 
New quality measure for SNP array based CNV detection.
Macé A., Tuke M.A., Beckmann J.S., Lin L., Jacquemont S., Weedon M.N., Reymond A., Kutalik Z., 2016/11/01. Bioinformatics (Oxford, England), 32 (21) pp. 3298-3305. Peer-reviewed.
REPRESSOR OF ULTRAVIOLET-B PHOTOMORPHOGENESIS function allows efficient phototropin mediated ultraviolet-B phototropism in etiolated seedlings.
Vanhaelewyn L., Schumacher P., Poelman D., Fankhauser C., Van Der Straeten D., Vandenbussche F., 2016/11. Plant science : an international journal of experimental plant biology, 252 pp. 215-221. Peer-reviewed.
 
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.
Fumagalli F., Noack J., Bergmann T.J., Cebollero E., Pisoni G.B., Fasana E., Fregno I., Galli C., Loi M., Soldà T. et al., 2016/11. Nature cell biology, 18 (11) pp. 1173-1184. Peer-reviewed.
 
High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine.
Tomas J., Mulet C., Saffarian A., Cavin J.B., Ducroc R., Regnault B., Kun Tan C., Duszka K., Burcelin R., Wahli W. et al., 2016/10/04. Proceedings of the National Academy of Sciences of the United States of America, 113 (40) pp. E5934-E5943. Peer-reviewed.
 
Contrôle de l’homéostasie glucido-lipidique par les facteurs du cycle cellulaire CDK4 et E2F1 [Cell cycle regulators CDK4 and E2F1 control glucose and lipid homeostasis]
Denechaud P.D., Lopez-Mejia I.C., Fajas L., 2016/10. Medecine sciences : M/S, 32 (10) pp. 815-818.
 
Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency.
Zarei M., Barroso E., Leiva R., Barniol-Xicota M., Pujol E., Escolano C., Vázquez S., Palomer X., Pardo V., González-Rodríguez Á. et al., 2016/10. Diabetes, 65 (10) pp. 3185-3199. Peer-reviewed.
Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition.
Nikolaeva S., Ansermet C., Centeno G., Pradervand S., Bize V., Mordasini D., Henry H., Koesters R., Maillard M., Bonny O. et al., 2016/10. Journal of the American Society of Nephrology : JASN, 27 (10) pp. 2997-3004. Peer-reviewed.
 
Sex-Specific Control of Fat Mass and Counterregulation by Hypothalamic Glucokinase.
Steinbusch L.K., Picard A., Bonnet M.S., Basco D., Labouèbe G., Thorens B., 2016/10. Diabetes, 65 (10) pp. 2920-2931. Peer-reviewed.
 
Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.
Tan N.S., Vázquez-Carrera M., Montagner A., Sng M.K., Guillou H., Wahli W., 2016/10. Progress in lipid research, 64 pp. 98-122.
Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila.
Knecht Z.A., Silbering A.F., Ni L., Klein M., Budelli G., Bell R., Abuin L., Ferrer A.J., Samuel A.D., Benton R. et al., 2016/09/22. eLife, 5 p. 17879. Peer-reviewed.
An expanded evaluation of protein function prediction methods shows an improvement in accuracy.
Jiang Y., Oron T.R., Clark W.T., Bankapur A.R., D'Andrea D., Lepore R., Funk C.S., Kahanda I., Verspoor K.M., Ben-Hur A. et al., 2016/09/07. Genome Biology, 17 (1) p. 184. Peer-reviewed.
 
GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability.
Lodder E.M., De Nittis P., Koopman C.D., Wiszniewski W., Moura de Souza C.F., Lahrouchi N., Guex N., Napolioni V., Tessadori F., Beekman L. et al., 2016/09/01. American journal of human genetics, 99 (3) pp. 704-710. Peer-reviewed.
 
Histomorphological Phenotyping of the Adult Mouse Brain.
Mikhaleva A., Kannan M., Wagner C., Yalcin B., 2016/09/01. Current protocols in mouse biology, 6 (3) pp. 307-332. Peer-reviewed.
 
An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model.
Atkins M., Potier D., Romanelli L., Jacobs J., Mach J., Hamaratoglu F., Aerts S., Halder G., 2016/08/22. Current biology, 26 (16) pp. 2101-2113. Peer-reviewed.
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A., Frera G., Lugrin J., Jamilloux Y., Hsu E.T., Tardivel A., De Gassart A., Zaffalon L., Bujisic B., Siegert S. et al., 2016/08/09. Proceedings of the National Academy of Sciences of the United States of America, 113 (32) pp. E4671-80. Peer-reviewed.
 
De novo PIK3R2 variant causes polymicrogyria, corpus callosum hyperplasia and focal cortical dysplasia.
Terrone G., Voisin N., Abdullah Alfaiz A., Cappuccio G., Vitiello G., Guex N., D'Amico A., James Barkovich A., Brunetti-Pierri N., Del Giudice E. et al., 2016/08. European journal of human genetics, 24 (9) pp. 1359-1362. Peer-reviewed.
Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web.
Robinson O., Dylus D., Dessimoz C., 2016/08. Molecular biology and evolution, 33 (8) pp. 2163-2166. Peer-reviewed.
Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span.
Gat-Yablonski G., Finka A., Pinto G., Quadroni M., Shtaif B., Goloubinoff P., 2016/08. Aging, 8 (8) pp. 1735-1758. Peer-reviewed.
 
Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice.
Sala-Rabanal M., Hirayama B.A., Ghezzi C., Liu J., Huang S.C., Kepe V., Koepsell H., Yu A., Powell D.R., Thorens B. et al., 2016/08/01. The Journal of physiology, 594 (15) pp. 4425-4438. Peer-reviewed.
Clade-level Spatial Modelling of HPAI H5N1 Dynamics in the Mekong Region Reveals New Patterns and Associations with Agro-Ecological Factors.
Artois J., Newman S.H., Dhingra M.S., Chaiban C., Linard C., Cattoli G., Monne I., Fusaro A., Xenarios I., Engler R. et al., 2016/07/25. Scientific reports, 6 p. 30316. Peer-reviewed.
The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition.
Hippolyte L., Maillard A.M., Rodriguez-Herreros B., Pain A., Martin-Brevet S., Ferrari C., Conus P., Macé A., Hadjikhani N., Metspalu A. et al., 2016/07/15. Biological psychiatry, 80 (2) pp. 129-139. Peer-reviewed.
 
West syndrome caused by homozygous variant in the evolutionary conserved gene encoding the mitochondrial elongation factor GUF1.
Alfaiz A.A., Müller V., Boutry-Kryza N., Ville D., Guex N., de Bellescize J., Rivier C., Labalme A., des Portes V., Edery P. et al., 2016/07. European journal of human genetics, 24 (7) pp. 1001-1008. Peer-reviewed.
 
Model of DNA topology simplification has come full (supercoiled) circle after two decades of research: Comment on "Disentangling DNA molecules" by Alexander Vologodskii.
Stasiak A., 2016/06/17. Physics of life reviews, 18 pp. 154-157.
How topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation.
Rawdon E.J., Dorier J., Racko D., Millett K.C., Stasiak A., 2016/06/02. Nucleic acids research, 44 (10) pp. 4528-4538. Peer-reviewed.
Clustering Genes of Common Evolutionary History.
Gori K., Suchan T., Alvarez N., Goldman N., Dessimoz C., 2016/06. Molecular biology and evolution, 33 (6) pp. 1590-1605. Peer-reviewed.
 
Sexual circuitry in Drosophila.
Auer T.O., Benton R., 2016/06. Current opinion in neurobiology, 38 pp. 18-26. Peer-reviewed.
Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.
Rodius S., Androsova G., Götz L., Liechti R., Crespo I., Merz S., Nazarov P.V., de Klein N., Jeanty C., González-Rosa J.M. et al., 2016/05/31. Scientific reports, 6 p. 26822. Peer-reviewed.
 
16p11.2 Locus modulates response to satiety before the onset of obesity.
Maillard A.M., Hippolyte L., Rodriguez-Herreros B., Chawner S.J., Dremmel D., Agüera Z., Fagundo A.B., Pain A., Martin-Brevet S., Hilbert A. et al., 2016/05. International journal of obesity, 40 (5) pp. 870-876. Peer-reviewed.
 
Light-Mediated Hormonal Regulation of Plant Growth and Development.
de Wit M., Galvão V.C., Fankhauser C., 2016/04/29. Annual review of plant biology, 67 pp. 513-537. Peer-reviewed.
The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila.
Ni L., Klein M., Svec K.V., Budelli G., Chang E.C., Ferrer A.J., Benton R., Samuel A.D., Garrity P.A., 2016/04/29. eLife, 5 pp. e13254. Peer-reviewed.
Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome.
Zimmer F., Harrison P.W., Dessimoz C., Mank J.E., 2016/04/25. Genome biology and evolution, 8 (4) pp. 1233-1242.
Hepatic Fasting-Induced PPARα Activity Does Not Depend on Essential Fatty Acids.
Polizzi A., Fouché E., Ducheix S., Lasserre F., Marmugi A.P., Mselli-Lakhal L., Loiseau N., Wahli W., Guillou H., Montagner A., 2016/04/24. International journal of molecular sciences, 17 (10) p. 1624. Peer-reviewed.
 
The Drosophila TNF Eiger Is an Adipokine that Acts on Insulin-Producing Cells to Mediate Nutrient Response.
Agrawal N., Delanoue R., Mauri A., Basco D., Pasco M., Thorens B., Léopold P., 2016/04/12. Cell metabolism, 23 (4) pp. 675-684.
Evidence for the fixation of gene duplications by positive selection in Drosophila.
Cardoso-Moreira M., Arguello J.R., Gottipati S., Harshman L.G., Grenier J.K., Clark A.G., 2016/04. Genome research, 26 (6) pp. 787-798. Peer-reviewed.
A photoreceptor's on-off switch.
Fankhauser C., Ulm R., 2016/03/21. Science (New York, N.Y.), 354 (6310) pp. 282-283. Peer-reviewed.
Bevacizumab specifically decreases elevated levels of circulating KIT+CD11b+ cells and IL-10 in metastatic breast cancer patients.
Cattin S., Fellay B., Pradervand S., Trojan A., Ruhstaller T., Rüegg C., Fürstenberger G., 2016/03/08. Oncotarget, 7 (10) pp. 11137-11150. Peer-reviewed.
Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest.
Orioli A., Praz V., Lhôte P., Hernandez N., 2016/03. Genome research, 26 (5) pp. 624-635. Peer-reviewed.
2C-Cas9: a versatile tool for clonal analysis of gene function.
Di Donato V., De Santis F., Auer T.O., Testa N., Sánchez-Iranzo H., Mercader N., Concordet J.P., Del Bene F., 2016. Genome Research, 26 (5) pp. 681-692.
A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism.
Gomez-Diaz C., Bargeton B., Abuin L., Bukar N., Reina J.H., Bartoi T., Graf M., Ong H., Ulbrich M.H., Masson J.F. et al., 2016. Nature Communications, 7 p. 11866.
 
A trilogy of glucocorticoid receptor actions.
Tan C.K., Wahli W., 2016. Proceedings of the National Academy of Sciences of the United States of America, 113 (5) pp. 1115-1117.
Alerting or Somnogenic Light: Pick Your Color.
Bourgin P., Hubbard J., 2016. PLoS Biology, 14 (8) pp. e2000111. Peer-reviewed.
Altered Sleep Homeostasis in Rev-erbα Knockout Mice.
Mang G.M., La Spada F., Emmenegger Y., Chappuis S., Ripperger J.A., Albrecht U., Franken P., 2016. Sleep, 39 (3) pp. 589-601. Peer-reviewed.
 
Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis.
Safdar A., Annis S., Kraytsberg Y., Laverack C., Saleem A., Popadin K., Woods D.C., Tilly J.L., Khrapko K., 2016. Current Opinion in Genetics and Development, 38 pp. 127-132. Peer-reviewed.
Analyzing the temporal regulation of translation efficiency in mouse liver.
Janich P., Arpat A.B., Castelo-Szekely V., Gatfield D., 2016. Genomics Data, 8 pp. 41-44. Peer-reviewed.
Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina.
Emery M., Nanchen N., Preitner F., Ibberson M., Roduit R., 2016. Plos One, 11 (2) pp. e0150266. Peer-reviewed.
 
Can Dissipative Properties of Single Molecules Be Extracted from a Force Spectroscopy Experiment?
Benedetti F., Gazizova Y., Kulik A.J., Marszalek P.E., Klinov D.V., Dietler G., Sekatskii S.K., 2016. Biophysical Journal, 111 (6) pp. 1163-1172.
Caspase-mediated cleavage of raptor participates in the inactivation of mTORC1 during cell death.
Martin R., Desponds C., Eren R.O., Quadroni M., Thome M., Fasel N., 2016. Cell Death Discovery, 2 p. 16024. Peer-reviewed.
Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways.
Crippa S., Nemir M., Ounzain S., Ibberson M., Berthonneche C., Sarre A., Boisset G., Maison D., Harshman K., Xenarios I. et al., 2016. Cardiovascular Research, 110 (1) pp. 73-84. Peer-reviewed.
Compensatory embryonic response to allele-specific inactivation of the murine X-linked gene Hcfc1.
Minocha S., Sung T.L., Villeneuve D., Lammers F., Herr W., 2016. Developmental Biology, 412 (1) pp. 1-17. Peer-reviewed.
Complete Genome Sequence of Mycoplasma mycoides subsp. mycoides T1/44, a Vaccine Strain against Contagious Bovine Pleuropneumonia.
Gourgues G., Barré A., Beaudoing E., Weber J., Magdelenat G., Barbe V., Schieck E., Jores J., Vashee S., Blanchard A. et al., 2016. Genome Announcements, 4 (2) pp. e00263-16. Peer-reviewed.
Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase
Cinesi Cinzia, Aeschbach Lorène, Yang Bin, Dion Vincent, 2016. Nature Communications, 7 p. 13272. Peer-reviewed.
Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities.
D'Angelo D., Lebon S., Chen Q., Martin-Brevet S., Snyder L.G., Hippolyte L., Hanson E., Maillard A.M., Faucett W.A., Macé A. et al., 2016. Jama Psychiatry, 73 (1) pp. 20-30. Peer-reviewed.
 
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
Denechaud P.D., Lopez-Mejia I.C., Giralt A., Lai Q., Blanchet E., Delacuisine B., Nicolay B.N., Dyson N.J., Bonner C., Pattou F. et al., 2016. Journal of Clinical Investigation, 126 (1) pp. 137-150.
Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility.
Nuttle X., Giannuzzi G., Duyzend M.H., Schraiber J.G., Narvaiza I., Sudmant P.H., Penn O., Chiatante G., Malig M., Huddleston J. et al., 2016. Nature, 536 (7615) pp. 205-209. Peer-reviewed.
Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification.
Minocha S., Bessonnard S., Sung T.L., Moret C., Constam D.B., Herr W., 2016. Developmental Biology, 91 (4) pp. 294-297. Peer-reviewed.
Erratum: Multimodal stimulus coding by a gustatory sensory neuron in Drosophila larvae.
van Giesen L., Hernandez-Nunez L., Delasoie-Baranek S., Colombo M., Renaud P., Bruggmann R., Benton R., Samuel A.D., Sprecher S.G., 2016. Nature Communications, 7 p. 11028. Peer-reviewed.
Every day I dream ...&quot; An interview with the Rwandan Health Minister.
Suter P.M., Wahli W., 2016. Swiss Medical Weekly, 146 pp. w14316.
Extension of human lncRNA transcripts by RACE coupled with long-read high-throughput sequencing (RACE-Seq).
Lagarde J., Uszczynska-Ratajczak B., Santoyo-Lopez J., Gonzalez J.M., Tapanari E., Mudge J.M., Steward C.A., Wilming L., Tanzer A., Howald C. et al., 2016. Nature Communications, 7 p. 12339. Peer-reviewed.
Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.
Arguello J.R., Cardoso-Moreira M., Grenier J.K., Gottipati S., Clark A.G., Benton R., 2016. Nature Communications, 7 pp. ncomms11855.
 
Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance.
Schieck E., Lartigue C., Frey J., Vozza N., Hegermann J., Miller R.A., Valguarnera E., Muriuki C., Meens J., Nene V. et al., 2016. Molecular Microbiology, 99 (1) pp. 55-70.
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.
Nicod J., Davies R.W., Cai N., Hassett C., Goodstadt L., Cosgrove C., Yee B.K., Lionikaite V., McIntyre R.E., Remme C.A. et al., 2016. Nature Genetics, 48 (8) pp. 912-918. Peer-reviewed.
Genomic insights into the Ixodes scapularis tick vector of Lyme disease.
Gulia-Nuss M., Nuss A.B., Meyer J.M., Sonenshine D.E., Roe R.M., Waterhouse R.M., Sattelle D.B., de la Fuente J., Ribeiro J.M., Megy K. et al., 2016. Nature Communications, 7 (10507) p. 10507. Peer-reviewed.
Global mapping of highly pathogenic avian influenza H5N1 and H5Nx clade 2.3.4.4 viruses with spatial cross-validation.
Dhingra M.S., Artois J., Robinson T.P., Linard C., Chaiban C., Xenarios I., Engler R., Liechti R., Kuznetsov D., Xiao X. et al., 2016. eLife, 5 pp. e19571. Peer-reviewed.
Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism.
Rando G., Tan C.K., Khaled N., Montagner A., Leuenberger N., Bertrand-Michel J., Paramalingam E., Guillou H., Wahli W., 2016. Elife, 5 pp. e28536. Peer-reviewed.
Glucose-responsive neurons of the paraventricular thalamus control sucrose-seeking behavior.
Labouèbe G., Boutrel B., Tarussio D., Thorens B., 2016. Nature Neuroscience, 19 (8) pp. 999-1002.
Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.
Lavoie S., Steullet P., Kulak A., Preitner F., Do K.Q., Magistretti P.J., 2016. Frontiers in Physiology, 7 p. 142. Peer-reviewed.
 
Homology-Independent Integration of Plasmid DNA into the Zebrafish Genome.
Auer T.O., Del Bene F., 2016. Methods in molecular biology, 1451 pp. 31-51. Peer-reviewed.
Identification and molecular characterisation of Lausanne Institutional Biobank participants with familial hypercholesterolaemia - a proof-of-concept study.
Maurer F., Pradervand S., Guilleret I., Nanchen D., Maghraoui A., Chapatte L., Bojkowska K., Bhuiyan Z.A., Jacquemont N., Harshman K. et al., 2016. Swiss medical weekly, 146 pp. w14326. Peer-reviewed.
Identification of a novel PPARβ/δ/miR-21-3p axis in UV-induced skin inflammation.
Degueurce G., D'Errico I., Pich C., Ibberson M., Schütz F., Montagner A., Sgandurra M., Mury L., Jafari P., Boda A. et al., 2016. EMBO Molecular Medicine, 8 (8) pp. 919-936. Peer-reviewed.
Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics.
Loviglio M.N., Beck C.R., White J.J., Leleu M., Harel T., Guex N., Niknejad A., Bi W., Chen E.S., Crespo I. et al., 2016. Genome medicine, 8 (1) p. 105. Peer-reviewed.
Identification of Antigenic Proteins from Lichtheimia corymbifera for Farmer's Lung Disease Diagnosis.
Rognon B., Barrera C., Monod M., Valot B., Roussel S., Quadroni M., Jouneau S., Court-Fortune I., Caillaud D., Fellrath J.M. et al., 2016. PLoS One, 11 (8) pp. e0160888. Peer-reviewed.
Identification, visualization and clonal analysis of intestinal stem cells in fish.
Aghaallaei N., Gruhl F., Schaefer C.Q., Wernet T., Weinhardt V., Centanin L., Loosli F., Baumbach T., Wittbrodt J., 2016. Development, 143 (19) pp. 3470-3480. Peer-reviewed.
In Search of Functional Advantages of Knots in Proteins.
Dabrowski-Tumanski P., Stasiak A., Sulkowska J.I., 2016. PLoS One, 11 (11) pp. e0165986. Peer-reviewed.
 
Inter-varietal structural variation in grapevine genomes.
Cardone M.F., D'Addabbo P., Alkan C., Bergamini C., Catacchio C.R., Anaclerio F., Chiatante G., Marra A., Giannuzzi G., Perniola R. et al., 2016. Plant Journal, 88 (4) pp. 648-661. Peer-reviewed.
Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction.
Duszka K., Picard A., Ellero-Simatos S., Chen J., Defernez M., Paramalingam E., Pigram A., Vanoaica L., Canlet C., Parini P. et al., 2016. Scientific Reports, 6 p. 36937. Peer-reviewed.
 
Ir40a neurons are not DEET detectors.
Silbering A.F., Bell R., Münch D., Cruchet S., Gomez-Diaz C., Laudes T., Galizia C.G., Benton R., 2016. Nature, 534 (7608) pp. E5-E7. Peer-reviewed.
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.
Montagner A., Polizzi A., Fouché E., Ducheix S., Lippi Y., Lasserre F., Barquissau V., Régnier M., Lukowicz C., Benhamed F. et al., 2016. Gut, 65 (7) pp. 1202-1214. Peer-reviewed.
Membrane Proteins Are Dramatically Less Conserved than Water-Soluble Proteins across the Tree of Life.
Sojo V., Dessimoz C., Pomiankowski A., Lane N., 2016. Molecular Biology and Evolution, 33 (11) pp. 2874-2884. Peer-reviewed.
 
Modulation of neural variability in premotor, motor, and posterior parietal cortex during change of motor intention.
Saberi-Moghadam S., Ferrari-Toniolo S., Ferraina S., Caminiti R., Battaglia-Mayer A., 2016. Journal of Neuroscience, 36 (16) pp. 4614-4623.
 
Multigenerational effects of the anticancer drug tamoxifen and its metabolite 4-hydroxy-tamoxifen on Daphnia pulex.
Borgatta M., Waridel P., Decosterd L.A., Buclin T., Chèvre N., 2016. Science of the Total Environment, 545-546 pp. 21-29.
Multimodal stimulus coding by a gustatory sensory neuron in Drosophila larvae.
van Giesen L., Hernandez-Nunez L., Delasoie-Baranek S., Colombo M., Renaud P., Bruggmann R., Benton R., Samuel A.D., Sprecher S.G., 2016. Nature Communications, 7 p. 10687. Peer-reviewed.
 
NANS-mediated synthesis of sialic acid is required for brain and skeletal development.
van Karnebeek C.D., Bonafé L., Wen X.Y., Tarailo-Graovac M., Balzano S., Royer-Bertrand B., Ashikov A., Garavelli L., Mammi I., Turolla L. et al., 2016. Nature Genetics, 48 (7) pp. 777-784. Peer-reviewed.
 
Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity.
Tafti M., Lammers G.J., Dauvilliers Y., Overeem S., Mayer G., Nowak J., Pfister C., Dubois V., Eliaou J.F., Eberhard H.P. et al., 2016. Sleep, 39 (3) pp. 581-587. Peer-reviewed.
 
New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach.
Zufferey A., Ibberson M., Reny J.L., Nolli S., Schvartz D., Docquier M., Xenarios I., Sanchez J.C., Fontana P., 2016. Human Genetics, 135 (4) pp. 403-414. Peer-reviewed.
 
Photomorphogenesis and Photoreceptors
de Wit M., Pierik R, 2016. pp. 171-186 dans Hikosaka K., Niinemets U., Anten N.P.R. (eds.) Canopy Photosynthesis: From Basics to Applications, Springer.
Prevalence and determinants of periodic limb movements in the general population.
Haba-Rubio J., Marti-Soler H., Marques-Vidal P., Tobback N., Andries D., Preisig M., Waeber G., Vollenweider P., Kutalik Z., Tafti M. et al., 2016. Annals of Neurology, 79 (3) pp. 464-474. Peer-reviewed.
Proteolysis of HCF-1 by Ser/Thr glycosylation-incompetent O-GlcNAc transferase:UDP-GlcNAc complexes.
Kapuria V., Röhrig U.F., Bhuiyan T., Borodkin V.S., van Aalten D.M., Zoete V., Herr W., 2016. Genes and Development, 30 (8) pp. 960-972. Peer-reviewed.
Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes.
Arbogast T., Ouagazzal A.M., Chevalier C., Kopanitsa M., Afinowi N., Migliavacca E., Cowling B.S., Birling M.C., Champy M.F., Reymond A. et al., 2016. PLoS Genetics, 12 (2) pp. e1005709. Peer-reviewed.
 
Reporting incidental findings of genomic disorder-associated copy number variants to unselected biobank participants
Leitsalu L., Alavere H., Jacquemont S., Kolk A., Maillard A.M., Reigo A., Noukas M., Reymond A., Mannik K., Ng P.C. et al., 2016. Personalized Medicine, 13 (4) pp. 303-314.
Partagez:
Unicentre - CH-1015 Lausanne
Suisse
Tél. +41 21 692 11 11
Swiss University